Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionunmethylated CpG binding

KDM2B CXXC1 MBD1

3.28e-0710293GO:0045322
GeneOntologyMolecularFunctionco-receptor binding

DKK4 DKK3 WNT9B

7.80e-0713293GO:0039706
GeneOntologyMolecularFunctionzinc ion binding

APIP CXXC5 KDM2B ADAMTS20 ZSWIM8 PRKCG ADAM8 CXXC1 MBD1

3.01e-06891299GO:0008270
GeneOntologyMolecularFunctionreceptor antagonist activity

PXDN DKK4 DKK3

1.33e-0532293GO:0048019
GeneOntologyMolecularFunctiontransition metal ion binding

APIP CXXC5 KDM2B ADAMTS20 ZSWIM8 PRKCG ADAM8 CXXC1 MBD1

3.09e-051189299GO:0046914
GeneOntologyMolecularFunctionsignaling receptor inhibitor activity

PXDN DKK4 DKK3

4.01e-0546293GO:0030547
GeneOntologyMolecularFunctionmethyl-CpG binding

CXXC5 MBD1

9.23e-0431292GO:0008327
GeneOntologyMolecularFunctiongrowth factor binding

PXDN TEK ITGB4

1.47e-03156293GO:0019838
Domainzf-CXXC

CXXC5 KDM2B CXXC1 MBD1

1.77e-0911304PF02008
DomainZnf_CXXC

CXXC5 KDM2B CXXC1 MBD1

1.77e-0911304IPR002857
DomainZF_CXXC

CXXC5 KDM2B CXXC1 MBD1

1.77e-0911304PS51058
DomainVWC

KCP PXDN CRIM1

1.19e-0528303PF00093
DomainDickkopf_N

DKK4 DKK3

1.49e-054302IPR006796
DomainDickkopf_N

DKK4 DKK3

1.49e-054302PF04706
DomainVWFC_1

KCP PXDN CRIM1

2.58e-0536303PS01208
DomainVWC

KCP PXDN CRIM1

3.04e-0538303SM00214
DomainVWFC_2

KCP PXDN CRIM1

3.04e-0538303PS50184
DomainVWF_dom

KCP PXDN CRIM1

4.12e-0542303IPR001007
DomainEGF_extracell

TEK ADAM8 ITGB4

1.20e-0460303IPR013111
DomainEGF_2

TEK ADAM8 ITGB4

1.20e-0460303PF07974
DomainVWC_out

KCP CRIM1

4.19e-0419302SM00215
DomainEGF_1

LAMB4 TEK ADAM8 ITGB4

7.03e-04255304PS00022
DomainEGF-like_CS

LAMB4 TEK ADAM8 ITGB4

7.67e-04261304IPR013032
DomainEGF_2

LAMB4 TEK ADAM8 ITGB4

8.12e-04265304PS01186
DomainPeptidase_M12B_N

ADAMTS20 ADAM8

1.78e-0339302IPR002870
DomainPep_M12B_propep

ADAMTS20 ADAM8

1.78e-0339302PF01562
DomainDISINTEGRIN_1

ADAMTS20 ADAM8

1.87e-0340302PS00427
DomainADAM_MEPRO

ADAMTS20 ADAM8

1.87e-0340302PS50215
DomainDISINTEGRIN_2

ADAMTS20 ADAM8

1.87e-0340302PS50214
DomainReprolysin

ADAMTS20 ADAM8

1.87e-0340302PF01421
DomainPeptidase_M12B

ADAMTS20 ADAM8

1.87e-0340302IPR001590
DomainDisintegrin_dom

ADAMTS20 ADAM8

1.97e-0341302IPR001762
DomainZnf_PHD-finger

KDM2B CXXC1

7.12e-0379302IPR019787
DomainMetalloPept_cat_dom

ADAMTS20 ADAM8

7.47e-0381302IPR024079
Domain-

ADAMTS20 ADAM8

7.47e-03813023.40.390.10
DomainPHD

KDM2B CXXC1

8.96e-0389302SM00249
DomainZnf_PHD

KDM2B CXXC1

9.35e-0391302IPR001965
DomainZF_PHD_2

KDM2B CXXC1

1.02e-0295302PS50016
DomainZF_PHD_1

KDM2B CXXC1

1.04e-0296302PS01359
DomainZINC_PROTEASE

ADAMTS20 ADAM8

1.08e-0298302PS00142
PathwayKEGG_MEDICUS_REFERENCE_TGFA_EGFR_PLCG_PKC_SIGNALING_PATHWAY

PRKCG PLCG2

8.40e-058252M47479
PathwayKEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_EGFR_TO_PLCG_ERK_SIGNALING_PATHWAY

PRKCG PLCG2

2.71e-0414252M47383
PathwayKEGG_MEDICUS_VARIANT_EML4_ALK_FUSION_KINASE_TO_PLCG_ERK_SIGNALING_PATHWAY

PRKCG PLCG2

2.71e-0414252M47384
PathwayKEGG_MEDICUS_REFERENCE_EGF_EGFR_PLCG_ERK_SIGNALING_PATHWAY

PRKCG PLCG2

3.13e-0415252M47382
PathwayWP_HAIR_FOLLICLE_DEVELOPMENT_CYTODIFFERENTIATION_STAGE_3_OF_3

ADAMTS20 DKK4 DKK3

4.73e-0487253M39465
PathwayKEGG_MEDICUS_REFERENCE_CXCL12_CXCR4_PKC_ERK_SIGNALING_PATHAWAY

PRKCG PLCG2

5.07e-0419252M47596
Pubmed

DNA Sequence Recognition of Human CXXC Domains and Their Structural Determinants.

CXXC5 KDM2B MBD1

6.92e-081030329276034
Pubmed

Cloning and characterization of the gene encoding the mouse homologue of CpG binding protein.

CXXC1 MBD1

7.19e-07230212242013
Pubmed

Discovery of novel protein partners of the transcription factor FOXL2 provides insights into its physiopathological roles.

CXXC5 PAN2 ZSWIM8

1.67e-062730322544055
Pubmed

Kremen2 modulates Dickkopf2 activity during Wnt/LRP6 signaling.

DKK4 DKK3

2.16e-06330212527209
Pubmed

Expression of all Wnt genes and their secreted antagonists during mouse blastocyst and postimplantation development.

DKK4 DKK3 WNT9B

2.31e-063030315880404
Pubmed

Transcriptional analysis of cleft palate in TGFβ3 mutant mice.

KCP ITGB4 WNT9B

3.72e-063530332913205
Pubmed

Comprehensive expression analysis of all Wnt genes and their major secreted antagonists during mouse limb development and cartilage differentiation.

DKK4 DKK3 WNT9B

3.72e-063530319185060
Pubmed

Transcriptional silencing of Dickkopf gene family by CpG island hypermethylation in human gastrointestinal cancer.

DKK4 DKK3

4.31e-06430218461655
Pubmed

Functional and structural diversity of the human Dickkopf gene family.

DKK4 DKK3

7.18e-06530210570958
Pubmed

Stromal R-spondin orchestrates gastric epithelial stem cells and gland homeostasis.

DKK4 DKK3 WNT9B

9.15e-064730328813421
Pubmed

Members of the WNT signaling pathways are widely expressed in mouse ovaries, oocytes, and cleavage stage embryos.

DKK4 DKK3 WNT9B

9.15e-064730318351675
Pubmed

Wnt antagonist gene polymorphisms and renal cancer.

DKK4 DKK3

1.08e-05630219562778
Pubmed

Characterisation of the Wnt antagonists and their response to conditionally activated Wnt signalling in the developing mouse forebrain.

DKK4 DKK3

1.08e-05630215527894
Pubmed

A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.

ZSWIM8 PRKCG ITGB4 CXXC1 DKK3 MBD1

1.16e-0560830616713569
Pubmed

Ventricular Netrin-1 deficiency leads to defective pyramidal decussation and mirror movement in mice.

PRKCG DKK3

2.01e-05830238760361
Pubmed

Dkk3-Cre BAC transgenic mouse line: a tool for highly efficient gene deletion in retinal progenitor cells.

PRKCG DKK3

3.94e-051130217661397
Pubmed

Heightened activation of embryonic megakaryocytes causes aneurysms in the developing brain of mice lacking podoplanin.

PLCG2 TEK

6.50e-051430233619517
Pubmed

AP-2α and AP-2β cooperatively function in the craniofacial surface ectoderm to regulate chromatin and gene expression dynamics during facial development.

DKK4 WNT9B

7.50e-051530235333176
Pubmed

Signal peptide prediction based on analysis of experimentally verified cleavage sites.

CRIM1 TEK DKK4 DKK3

7.61e-0526430415340161
Pubmed

Regional Control of Hairless versus Hair-Bearing Skin by Dkk2.

DKK4 DKK3

8.57e-051630230509557
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

CXXC5 PPP4R1 ZSWIM8 CRIM1 DKK3 MBD1 SPRYD7

8.92e-05128530735914814
Pubmed

Wnt signaling in the murine diastema.

DKK4 DKK3

9.70e-051730221531785
Pubmed

Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism.

PPP4R1 ZSWIM8 ADAM8 ITGB4 MBD1 SPRYD7

1.20e-0492530628986522
Pubmed

The molecular anatomy of mammalian upper lip and primary palate fusion at single cell resolution.

DKK4 WNT9B

1.35e-042030231118233
Pubmed

Expressed sequence tag analysis of human RPE/choroid for the NEIBank Project: over 6000 non-redundant transcripts, novel genes and splice variants.

ZSWIM8 TEK ITGB4

1.41e-0411730312107410
Pubmed

Coronary development is regulated by ATP-dependent SWI/SNF chromatin remodeling component BAF180.

TEK WNT9B

1.50e-042130218508041
Pubmed

Patterns of Wnt pathway activity in the mouse incisor indicate absence of Wnt/beta-catenin signaling in the epithelial stem cells.

DKK4 DKK3

1.50e-042130219806668
Pubmed

Cbx4 maintains the epithelial lineage identity and cell proliferation in the developing stratified epithelium.

KDM2B ITGB4

1.64e-042230226711500
Pubmed

Stabilization of VEGFR2 signaling by cerebral cavernous malformation 3 is critical for vascular development.

PLCG2 TEK

1.96e-042430220371769
Pubmed

Release of calcium from inositol 1,4,5-trisphosphate receptor-regulated stores by HIV-1 Tat regulates TNF-alpha production in human macrophages.

PRKCG PLCG2

1.96e-042430210843712
Pubmed

Bhlhb5 regulates the postmitotic acquisition of area identities in layers II-V of the developing neocortex.

PRKCG CRIM1

2.31e-042630218957218
Pubmed

Mechanism of HIV-1-TAT induction of interleukin-1beta from human monocytes: Involvement of the phospholipase C/protein kinase C signaling cascade.

PRKCG PLCG2

2.49e-042730220336759
Pubmed

Conditionals by inversion provide a universal method for the generation of conditional alleles.

TEK DKK4

2.49e-042730223918385
Pubmed

DLK1 is a novel regulator of bone mass that mediates estrogen deficiency-induced bone loss in mice.

PLCG2 ADAM8 DKK3

2.65e-0414530321308776
Pubmed

Crim1 has cell-autonomous and paracrine roles during embryonic heart development.

CRIM1 TEK

3.29e-043130226821812
Pubmed

Multiplexed barcoded CRISPR-Cas9 screening enabled by CombiGEM.

KDM2B MBD1

3.74e-043330226864203
Pubmed

Endothelial Cyp26b1 restrains murine heart valve growth during development.

TEK ITGB4 WNT9B

3.74e-0416330335364055
Pubmed

Links between alpha-catenin, NF-kappaB, and squamous cell carcinoma in skin.

ADAM8 ITGB4

4.20e-043530216452166
Pubmed

Tracing the origin of hair follicle stem cells.

ADAMTS20 DKK4

4.20e-043530234108685
Pubmed

Expression patterns of Wnts, Frizzleds, sFRPs, and misexpression in transgenic mice suggesting a role for Wnts in pancreas and foregut pattern formation.

DKK3 WNT9B

4.45e-043630212412008
Pubmed

Signaling pathways triggered by HIV-1 Tat in human monocytes to induce TNF-alpha.

PRKCG PLCG2

4.96e-043830212482669
Pubmed

Epidermal Wnt controls hair follicle induction by orchestrating dynamic signaling crosstalk between the epidermis and dermis.

DKK4 WNT9B

4.96e-043830223190887
Pubmed

PCGF homologs, CBX proteins, and RYBP define functionally distinct PRC1 family complexes.

KDM2B MGA

5.78e-044130222325352
Pubmed

The European renal genome project: an integrated approach towards understanding the genetics of kidney development and disease.

MGA SLCO6A1 EBF4

8.03e-0421230319521566
Pubmed

Wnt antagonist SFRP3 inhibits the differentiation of mouse hepatic progenitor cells.

DKK3 WNT9B

8.25e-044930219562671
Pubmed

Epigenetic-focused CRISPR/Cas9 screen identifies (absent, small, or homeotic)2-like protein (ASH2L) as a regulator of glioblastoma cell survival.

CXXC1 SPRYD7

8.59e-045030237974198
GeneFamilyZinc fingers CXXC-type

CXXC5 KDM2B CXXC1 MBD1

6.62e-1012214136
GeneFamilyPHD finger proteins

KDM2B CXXC1

4.84e-039021288
GeneFamilyADAM metallopeptidase domain containing|CD molecules

TEK ADAM8 ITGB4

1.02e-02394213471
GeneFamilyFibronectin type III domain containing

TEK ITGB4

1.46e-02160212555
CoexpressionNABA_ECM_GLYCOPROTEINS

KCP LAMB4 PXDN CRIM1

7.14e-05196304M3008
CoexpressionGSE22886_NAIVE_CD8_TCELL_VS_NKCELL_DN

ADAMTS20 PLCG2 CRIM1 ADAM8

7.28e-05197304M4421
CoexpressionGSE3982_EFF_MEMORY_CD4_TCELL_VS_TH2_UP

PAN2 DEFB126 ITGB4 MBD1

7.42e-05198304M5580
CoexpressionGSE22886_NAIVE_TCELL_VS_NKCELL_DN

ZSWIM8 PLCG2 CRIM1 ADAM8

7.42e-05198304M4415
CoexpressionNABA_MATRISOME

KCP ADAMTS20 LAMB4 PXDN CRIM1 ADAM8 WNT9B

1.27e-041026307M5889
CoexpressionWONG_ADULT_TISSUE_STEM_MODULE

KCNMA1 CXXC5 PXDN CRIM1 TEK DKK3

1.43e-04721306M1999
CoexpressionTIEN_INTESTINE_PROBIOTICS_2HR_DN

PPP4R1 CRIM1 DKK3

1.44e-0489303M8916
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_vein-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

CRIM1 TEK ITGB4 WNT9B

4.65e-06167304d7fe24cdc4b55a9555ce9e20699f5036b88148e9
ToppCelldroplet-Liver-LIVER_NPC-30m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATP11A CRIM1 TEK MGA

6.12e-06179304025d414ec88d5680d99c8173e70ee3bb0b694f74
ToppCellEndothelial-E|World / shred on cell class and cell subclass (v4)

CRIM1 TEK ITGB4 WNT9B

6.83e-06184304b4c561924c508536fd2112e91e32176b95fdf63a
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_vein|Children_(3_yrs) / Lineage, Cell type, age group and donor

CRIM1 TEK ITGB4 WNT9B

7.28e-06187304e35716f8b482be3bf5ab79f087a9caf67a9d197a
ToppCellCOVID-19-Endothelial_cells-Pulmonary_venous_endothelial_cells|COVID-19 / group, cell type (main and fine annotations)

CRIM1 TEK ITGB4 WNT9B

7.28e-061873042d20193a6cacdfa4877457c97b0077408942186c
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CRIM1 TEK ITGB4 WNT9B

7.75e-061903049b0ad888eb20acc011904d8593bc32bdef18d050
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CRIM1 TEK ITGB4 WNT9B

8.08e-06192304c157981b9a179925edcaabc0cb3b8805f0929004
ToppCellPND03-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CRIM1 TEK ITGB4 WNT9B

8.08e-06192304cd4c9b9ab17a779c154264f7459020f51e528ba5
ToppCelldistal-Endothelial-Vein-1|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CRIM1 TEK ITGB4 DKK3

8.94e-061973043d71c93da4b88ebbd58e68ed3dbf610d4bcfc4f5
ToppCellBronchus_Control_(B.)-Epithelial-TX-Basal_1|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

KCNMA1 PXDN PLAC8L1 ITGB4

9.12e-06198304f632342e1e8911dd82b5df171776a84c7dc3f931
ToppCelldistal-1-Endothelial-Vein|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CRIM1 TEK ITGB4 DKK3

9.12e-06198304eee6cb4fe0e1caf460869d5a0a57c9d259573f10
ToppCellBronchial-NucSeq-Endothelial-Endothelia_vascular-VE_pulmonary_venous|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CRIM1 TEK ITGB4 WNT9B

9.30e-061993043a4deea6e11a0555d27497b7c9983350797aac69
ToppCelldistal-Endothelial-Vein-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CRIM1 TEK ITGB4 DKK3

9.30e-06199304f9fc0482d7ab11f2165b30cce3564b4ff87d61a6
ToppCellBronchial-10x5prime-Endothelial-Endothelia_vascular-VE_pulmonary_venous|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CRIM1 TEK ITGB4 WNT9B

9.49e-0620030484e145619a500530f42ed0fe72468ae95f4cbf1e
ToppCelldistal-3-Endothelial-Vein|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CRIM1 TEK ITGB4 DKK3

9.49e-062003043a5c85bad2e7a9ecf55d90acb04178a343b3f5fd
ToppCellAdult-Endothelial-endothelial_cell_of_vein-D122|Adult / Lineage, Cell type, age group and donor

TEK ITGB4 WNT9B

1.67e-041603030cfe130606af433b2aa90e0a20b6c44659dd6fd4
ToppCell368C-Fibroblasts-Fibroblast-B_(Myofibroblast)|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

NRN1L ADAM8 DKK3

1.80e-04164303dd29decc6c41a580cfdf03962827ec18d432935f
ToppCell368C-Fibroblasts-Fibroblast-B_(Myofibroblast)-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

NRN1L ADAM8 DKK3

1.80e-04164303dcd3c3ee73900180451fad9b4de0efedbd375e1c
ToppCellEndothelial-endothelial_cell_of_bronchial_vessel|World / Lineage, Cell type, age group and donor

LAMB4 TEK ITGB4

1.83e-0416530384e553d699ac56df89a77248f7308b9133e1b683
ToppCellPND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-Chondrocyte-Chondrocyte_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KDM2B DKK3 EBF4

1.86e-0416630337794a84601a2a949d579663d4a4bb8bc8fb5923
ToppCellPND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-Chondrocyte|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KDM2B DKK3 EBF4

1.86e-0416630381c546c6d847e49e662b81e71992ca0f7a99e890
ToppCellFetal_29-31_weeks-Endothelial-endothelial_cell_of_vein-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CRIM1 TEK WNT9B

1.86e-04166303f7926ee266dcbf10df375cd921f1db5a2fa604f8
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6_IT-L6_IT_VISp_Col23a1_Adamts2|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PXDN CRIM1 ADAM8

1.93e-041683033fe432267656aff81b6d92c18d1b6fc0cde73d6a
ToppCellEndothelial-B-Donor_05|World / lung cells shred on cell class, cell subclass, sample id

TEK PLAC8L1 DKK3

1.93e-041683034977c3837fbb1f36c89fddd5764e37290ac25ad8
ToppCellfacs-Lung-nan-3m-Endothelial-vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRIM1 TEK ITGB4

2.00e-0417030367d7e1da3ebd2d14cb2e67799e94d655027ed5c4
ToppCellfacs-Lung-nan-3m-Endothelial-Vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRIM1 TEK ITGB4

2.00e-041703038e1f757ed62218c0fb6525f49d142dd2cd29acf9
ToppCellE16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TEK ITGB4 WNT9B

2.00e-04170303af8b56555cbd5a1016ab9ec2ce88225c58c89648
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_artery-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

PLCG2 TEK ITGB4

2.03e-041713031597459c971d6befa991d59dc66b41b6a522f797
ToppCellAT1-AT2_cells-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

PXDN ITGB4 DKK3

2.07e-041723030be41df5d35d818deb7316ac21c9366eb4b7bfd1
ToppCellE16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TEK ITGB4 WNT9B

2.07e-041723039a1743abcd5fbd38253ea84d88ad716cfb71de36
ToppCellE15.5-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_artery|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

PLCG2 TEK ITGB4

2.10e-04173303b0ff9808e38cb64a734ced498cd0546728746cd5
ToppCellAdult-Endothelial-endothelial_cell_of_lymph_vessel-D122|Adult / Lineage, Cell type, age group and donor

CRIM1 TEK DKK3

2.10e-04173303dba09ba9748871e38a16449d500ae4d7b405c42f
ToppCellPND07-Immune-Immune_Myeloid-DC-cDC1-cDC1_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KDM2B PRKCG ADAM8

2.10e-0417330328c98a9a54aa2cfa67464db4f628c9357ad185b9
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B-B_cell|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

CXXC5 PPP4R1 PLCG2

2.10e-04173303d56e337eae727a29cd53cfd628e1b3c0a98e1f51
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KCNMA1 DKK3 EBF4

2.14e-04174303c529f3674b784f872f4387ffdeb46aecb619976b
ToppCellE18.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TEK ITGB4 WNT9B

2.17e-041753032e54961846c65b185d9bd6e305dd81205579d890
ToppCellE18.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TEK ITGB4 WNT9B

2.17e-04175303efa6a05f7417d46141b6e635f258c126b7a03aa1
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell_prolif|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NRN1L TEK DKK3

2.17e-0417530390302e8a44858ef3b2a165b88284d4788d591a99
ToppCellAdult-Endothelial-endothelial_cell_of_vein|Adult / Lineage, Cell type, age group and donor

TEK ITGB4 WNT9B

2.21e-04176303043683c61c5d1a7f8a4666a612310246bd3d83a2
ToppCell356C-Endothelial_cells-Endothelial-D|356C / Donor, Lineage, Cell class and subclass (all cells)

PXDN CRIM1 TEK

2.25e-04177303a0b172f40e0df97a288a5549ae7066697ad469b3
ToppCelldroplet-Lung-nan-3m-Mesenchymal-pericyte_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNMA1 KCP EBF4

2.25e-0417730365709bd546cb1ec6aa2ddd8b2adb46e174eb9a9a
ToppCell3'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.3.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LAMB4 DKK4 DKK3

2.25e-041773039e65b39fd797b6ce204b6480415810d1923acee5
ToppCell356C-Endothelial_cells-Endothelial-D-|356C / Donor, Lineage, Cell class and subclass (all cells)

PXDN CRIM1 TEK

2.25e-04177303ab8f09e118e4df696b0b4d33f013da020bdbd351
ToppCell367C-Myeloid-Dendritic-cDC_activated|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

KDM2B ADAM8 EBF4

2.25e-04177303a0ff337f11bdb11959ac71805ff94be6b4ec1083
ToppCelldroplet-Lung-nan-3m-Mesenchymal-Pericyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNMA1 KCP EBF4

2.25e-041773038684d47a547e2a06496f15e8da0200ecddc431e0
ToppCellCOPD-Epithelial-Basal|Epithelial / Disease state, Lineage and Cell class

KCNMA1 ITGB4 DKK3

2.29e-04178303441d1dba720141891b11f404744c59834d80e6c5
ToppCellfacs-Lung-Endomucin-3m-Endothelial-Vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRIM1 ITGB4 WNT9B

2.29e-041783035cc182e6faa7ba5b88378d2c953be29bbbb95a7e
ToppCellfacs-Lung-18m-Endothelial-venous_endothelial-vein_endothelial_cell-vein_endothelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CRIM1 TEK ITGB4

2.29e-04178303ccd37575b60102f5e647c01546e8ff8fec638bd7
ToppCellPCW_13-14-Endothelial-Endothelial_mature-endo_arterial_(9)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

PLCG2 TEK ITGB4

2.29e-04178303c227da59dc7beb73f84405bf13356bdeb59d9338
ToppCellfacs-Lung-Endomucin-3m-Endothelial-vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRIM1 ITGB4 WNT9B

2.29e-04178303f9a16bc3f09c35c7d30e3809da024bc2dcf746ed
ToppCellfacs-Lung-18m-Endothelial-venous_endothelial|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CRIM1 TEK ITGB4

2.29e-0417830387b04753650e45f12299c8456fb980d6c0d5961c
ToppCellfacs-Lung-18m-Endothelial-venous_endothelial-vein_endothelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CRIM1 TEK ITGB4

2.29e-04178303ebfae386a518ea33911ba3ff40464c94d18ef695
ToppCelldroplet-Liver-LIVER_HEP|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRIM1 TEK DKK3

2.36e-04180303423454e3390080ae03bb3cbb267255ebfe4df080
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_vein-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

CRIM1 TEK ITGB4

2.36e-0418030327e8bbee388e64dd79d70b160b76d45b1f398006
ToppCellAT1_cells-Donor_05|World / lung cells shred on cell class, cell subclass, sample id

PXDN DKK3 SPRYD7

2.36e-04180303ff4728782c3ec814ba071cc22b7894abdd9da837
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_B-B_plasma-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

KCNMA1 CXXC5 PLCG2

2.36e-041803038e96f8646c002768b272359af485dc0ab57e0ccd
ToppCelldroplet-Liver-LIVER_HEP-30m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRIM1 TEK DKK3

2.36e-04180303dd1b10c7f5a0fbc63163844ca1882884a24a84d3
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-collecting_duct_principal_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS20 ITGB4 WNT9B

2.40e-041813037af469f5bcb9b1ab3f35b2758bf2afb87e8eba57
ToppCellfacs-Lung-3m-Endothelial-venous_endothelial-vein_endothelial_cell-vein_endothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CRIM1 TEK ITGB4

2.40e-0418130372c28baf4fd417ff4a7068603830d55074960144
ToppCellCOVID-19-Endothelial_cells-Endothelial_cells_(other)|COVID-19 / group, cell type (main and fine annotations)

PXDN CRIM1 TEK

2.40e-0418130326eb4ee57a70dbf54e096b73129fda9dfda1f6ec
ToppCellfacs-Lung-3m-Endothelial-venous_endothelial-vein_endothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CRIM1 TEK ITGB4

2.40e-041813032ac4d3e8987d5a009d7908d8787e18165826202a
ToppCelldroplet-Liver-nan-3m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATP11A CRIM1 TEK

2.40e-04181303fcc94f04dae98b817ec06b282d2e887804d37ae5
ToppCellfacs-Lung-3m-Endothelial-venous_endothelial|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CRIM1 TEK ITGB4

2.40e-041813032628c7ac345eaaeecf8e34617e81948925962cb9
ToppCellBasal|World / shred by cell class for mouse tongue

CRIM1 ITGB4 DKK3

2.48e-04183303c6729a207526ff4aa48176207b9353176f631fea
ToppCelldroplet-Heart-4Chambers-18m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRIM1 TEK ITGB4

2.48e-041833036c4a09c02e30e1f24dde39f8cb8c5b453826ee2e
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KCP CRIM1 DKK3

2.48e-041833038a799807fbf24456a9811e0c64068187940a2f71
ToppCellPCW_10-12-Endothelial-Endothelial_mature-endo_arterial_(9)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

PLCG2 TEK ITGB4

2.52e-04184303a809b0fa52df8a159f60f87eefcef61220af5e34
ToppCellPND07-28-samps-Mesenchymal-Myofibroblast-myofibroblast_-_mature_-_C|PND07-28-samps / Age Group, Lineage, Cell class and subclass

KCNMA1 PXDN DKK3

2.56e-04185303427176ad9ab8d9511200fb0a132cfd1e835fe35c
ToppCell(00)_Basal-(4)_1wkpi|(00)_Basal / shred by cell type and Timepoint

CRIM1 ITGB4 DKK3

2.56e-04185303bf82ba905e5eee1c39a2731702071d3de10a78b8
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_artery-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

CRIM1 TEK ITGB4

2.56e-04185303a7ae76058b2082020cadec49d63b9f4e24d21734
ToppCellCOVID-19-kidney-FLT1+PLVAP+EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

ATP11A PLCG2 TEK

2.56e-04185303673308ca0514a4d3629d61fe91e9d8fb31b72166
ToppCellControl-Endothelial-Endothelial-Vein|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TEK ITGB4 WNT9B

2.60e-0418630392092f11ecce22c14f244e42c499af0822977e6f
ToppCelldroplet-Lung-1m-Endothelial-arterial_endothelial|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CRIM1 TEK ITGB4

2.60e-04186303ffbc78058be8f0dc2e0335cc4c3195a636d17721
ToppCelldroplet-Lung-LUNG-30m-Endothelial-Vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRIM1 TEK ITGB4

2.60e-0418630341f1674afc17661eccaa779cdeb663db5e45685d
ToppCelldroplet-Lung-1m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CRIM1 TEK ITGB4

2.60e-04186303ed924852cd7132c8f6703522037dc22bd2c83193
ToppCell3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADAMTS20 PLCG2 CRIM1

2.60e-0418630320340a5b5cc7f07386498a4ef937d6fbc9e347c4
ToppCelldroplet-Lung-LUNG-30m-Endothelial-vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRIM1 TEK ITGB4

2.60e-04186303aa006650cf21a2c51dfe1091681f67fdad939107
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

KCNMA1 ADAMTS20 LAMB4

2.60e-0418630323b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCell367C-Endothelial_cells-Endothelial-D|367C / Donor, Lineage, Cell class and subclass (all cells)

PLCG2 TEK ITGB4

2.64e-041873031342bc614bc4045263c2eb0a535a1dd6c64e7abe
ToppCellLV-10._Endothelium_II|World / Chamber and Cluster_Paper

TEK ITGB4 WNT9B

2.64e-041873037876dcb4800c2e54874df3d933efb79307a64a97
ToppCell367C-Endothelial_cells-Endothelial-D-|367C / Donor, Lineage, Cell class and subclass (all cells)

PLCG2 TEK ITGB4

2.64e-041873037aa206262b14b9f2aaa99e59da38b96c3594d2c9
ToppCellP03-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_artery|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CXXC5 PLCG2 TEK

2.64e-0418730366ebe1788d51b3e17bec6cdb219f709756b4e530
ToppCellP03-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_vein|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

TEK ITGB4 WNT9B

2.68e-041883035eb107122064f0a99dfd445cc87d3766f7257216
ToppCelldroplet-Liver-LIVER_NPC-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRIM1 TEK DKK3

2.68e-041883030aa8747c2931b0c91f6d78bb2db8fd8ede6dd559
ToppCellP28-Endothelial-large_vessel_endothelial_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CRIM1 TEK ITGB4

2.68e-04188303263169029293e005bcffd87db20221fdd2d3917e
ToppCellCOVID-19-lung-Vein_EC|lung / Disease (COVID-19 only), tissue and cell type

CRIM1 TEK ITGB4

2.68e-04188303d582b76fc2faac526c9bf97503041129e1a6a211
ToppCellEndothelial-endothelial_cell_of_artery|World / Lineage, Cell type, age group and donor

PLCG2 TEK ITGB4

2.72e-04189303fdd89c71113ac99b7c800c6def8888e512ff1128
ToppCellCOVID-19-Heart-EC_(POSTN)|COVID-19 / Disease (COVID-19 only), tissue and cell type

CRIM1 TEK ITGB4

2.72e-041893037346c1112e2e155dbd71b6dbc80e680fd262a691
ToppCell3'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LAMB4 ITGB4 DKK4

2.72e-04189303c80610395d016acc855cfa451e47ea6cecb0556c
ToppCellHippocampus-Neuronal-Excitatory|Hippocampus / BrainAtlas - Mouse McCarroll V32

PRKCG PXDN DKK3

2.72e-041893034b90d181eb0a42814eeb23bc82e52fd3a12392a7
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KCNMA1 CRIM1 DKK3

2.72e-041893037ab1cfc1657277858339f7258a0c4ae9cb42fdf8
ToppCelldroplet-Liver-LIVER_NPC-30m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRIM1 TEK DKK3

2.77e-0419030325525fee1da8a808034d9c916159fd0b6b26bce8
ToppCelldroplet-Liver-LIVER_NPC-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRIM1 TEK DKK3

2.77e-04190303a08c5929b05a4969852e351a93c4e4deb4c8d5b6
ToppCellP07-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_vein|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

TEK ITGB4 WNT9B

2.77e-04190303e1b721bb74561fe51c53328a0394c9954e489049
ToppCellCOVID-19-lung-Vein_EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

CRIM1 TEK ITGB4

2.77e-041903031caeaef78326734c1e31a0c4739190d5c5a77b9e
ToppCellPBMC-Severe-Myeloid-Neutrophil-Neutrophil-Neu_4|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

PAN2 ZSWIM8 ADAM8

2.77e-041903033f0c7d130f66faea778fe567604edf1b4cdf85b3
ToppCell5'-Adult-LymphNode-Endothelial-lymphatic_endothelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TEK DKK3 WNT9B

2.77e-041903036b704deeb44e1ffa10e604d0e5612b022f6cd9a6
ToppCellP15-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_vein|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CRIM1 ITGB4 WNT9B

2.77e-04190303d072bb285bd34d518b958e7c9ad44739c60b359c
ToppCellLPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KCNMA1 KCP DKK3

2.81e-041913037853ac7dff649150e6ff27cd4c8cf7c1fc034ed4
ToppCellControl-Endothelial-VE_Venous|Control / Disease state, Lineage and Cell class

CRIM1 TEK DKK3

2.81e-04191303617546cf4883dedf3323e03a53ba5adec334cf8e
DrugAtractyloside potassium salt [102130-43-8]; Up 200; 5uM; MCF7; HT_HG-U133A

ZSWIM8 LAMB4 ATP11A ITGB4 MBD1

5.37e-061963053435_UP
Diseaseresponse to perphenazine

PXDN DKK3

3.20e-0426302GO_0097334
DiseaseMental deterioration

TEK SLCO6A1

3.99e-0429302HP_0001268
Diseasecoffee consumption

LAMB4 CXXC1

4.86e-0432302EFO_0004330
Diseasepancreatic ductal carcinoma (is_marker_for)

KDM2B ADAM8

1.76e-0361302DOID:3587 (is_marker_for)
Diseaseserum metabolite measurement

LAMB4 PLCG2 CRIM1 TEK SLCO6A1

2.44e-03945305EFO_0005653
Diseasesusceptibility to mumps measurement

KCNMA1 EBF4

2.65e-0375302EFO_0008404
Diseasesystemic scleroderma

KCP PXDN

3.39e-0385302EFO_0000717
Diseasecentral corneal thickness

ADAMTS20 CRIM1 CXXC1

3.75e-03309303EFO_0005213
DiseaseAdenoid Cystic Carcinoma

MGA ITGB4

4.65e-03100302C0010606
DiseaseBell's palsy

KCNMA1 MGA

4.83e-03102302EFO_0007167

Protein segments in the cluster

PeptideGeneStartEntry
CRCQERFEAGRCIMA

ADAM8

351

P78325
EMCDQSTRPCSQRRC

ADAMTS20

1511

P59510
LFSCEMENCSLCRCG

PAN2

656

Q504Q3
MENCSLCRCGSETVR

PAN2

661

Q504Q3
MRRACCFDCGRSERD

KCNMA1

706

Q12791
CRRPDCMFGCTCLKR

MGA

1071

Q8IWI9
RKCGACAACLRRMDC

MBD1

336

Q9UIS9
CAACLRRMDCGRCDF

MBD1

341

Q9UIS9
RRMDCGRCDFCCDKP

MBD1

346

Q9UIS9
CSCCEMNVHRRCVRS

PRKCG

131

P05129
IRCLRMGCRCIELDC

PLCG2

346

P16885
CNDRGRCSMGQCVCE

ITGB4

551

P16144
KRCGMCAPCRRRINC

CXXC5

261

Q7LFL8
ARMCGECEACRRTED

CXXC1

166

Q9P0U4
TRCRKCEACLRTECG

KDM2B

611

Q8NHM5
CRGLRRRCQRDAMCC

DKK4

66

Q9UBT3
RRCQRDAMCCPGTLC

DKK4

71

Q9UBT3
MCSRCCDRKSCGNRN

EBF4

161

Q9BQW3
CRECYCLNGREMCAL

CRIM1

626

Q9NZV1
MCRCREGVSGQRCDR

LAMB4

1146

A4D0S4
MCGKQRDCCVPADRR

DEFB126

51

Q9BYW3
CRGQRMLCTRDSECC

DKK3

171

Q9UBP4
MLCTRDSECCGDQLC

DKK3

176

Q9UBP4
MSGCDAREGDCCSRR

APIP

1

Q96GX9
MMRCCRRRCCCRQPP

NRN1L

1

Q496H8
RLILPRFCEMCCDCR

PPP4R1

211

Q8TF05
RDRRICFCGLFCPMC

PLAC8L1

81

A1L4L8
CLQCTCLRSRVRCMA

KCP

216

Q6ZWJ8
STCCECCNNIRCFMI

SLCO6A1

96

Q86UG4
MATSVLCCLRCCRDG

SPRYD7

1

Q5W111
EICRSCSAVLCCRMA

ATP11A

786

P98196
CPSRCLCFRTTVRCM

PXDN

36

Q92626
CKLRCSCNNGEMCDR

TEK

311

Q02763
VMFDRCRVTSCSCTC

ZSWIM8

176

A7E2V4
LARACSAGRMERCTC

WNT9B

131

O14905