Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	ligase activity, forming carbon-oxygen bonds	MARS1 WARS2 YARS1 PARS2 QARS1	4.50e-05	42	188	5	GO:0016875
GeneOntologyMolecularFunction	aminoacyl-tRNA ligase activity	MARS1 WARS2 YARS1 PARS2 QARS1	4.50e-05	42	188	5	GO:0004812
GeneOntologyMolecularFunction	MAP-kinase scaffold activity	MAPK8IP1 AKAP13 MAPK8IP2	2.19e-04	13	188	3	GO:0005078
GeneOntologyMolecularFunction	nucleoside-triphosphatase regulator activity	GBF1 IPO7 ECT2L CHN1 CHN2 BCR TBC1D9 ARHGEF10L TBC1D24 DLC1 TBC1D1 KIAA1755 AKAP13 ARHGEF26	3.31e-04	507	188	14	GO:0060589
GeneOntologyMolecularFunction	GTPase regulator activity	GBF1 IPO7 ECT2L CHN1 CHN2 BCR TBC1D9 ARHGEF10L TBC1D24 DLC1 TBC1D1 KIAA1755 AKAP13 ARHGEF26	3.31e-04	507	188	14	GO:0030695
GeneOntologyBiologicalProcess	amino acid activation	MARS1 AASDH WARS2 YARS1 PARS2 QARS1	3.66e-06	46	188	6	GO:0043038
GeneOntologyBiologicalProcess	negative regulation of glucocorticoid receptor signaling pathway	PER1 CLOCK CRY2	1.46e-05	6	188	3	GO:2000323
GeneOntologyBiologicalProcess	negative regulation of intracellular steroid hormone receptor signaling pathway	VPS18 PER1 CLOCK CRY2 NCOR2	3.03e-05	40	188	5	GO:0033144
GeneOntologyBiologicalProcess	tRNA aminoacylation for protein translation	MARS1 WARS2 YARS1 PARS2 QARS1	3.86e-05	42	188	5	GO:0006418
GeneOntologyBiologicalProcess	tRNA aminoacylation	MARS1 WARS2 YARS1 PARS2 QARS1	5.42e-05	45	188	5	GO:0043039
Domain	aa-tRNA-synth_I_CS	MARS1 WARS2 YARS1 QARS1	2.56e-05	18	185	4	IPR001412
Domain	AA_TRNA_LIGASE_I	MARS1 WARS2 YARS1 QARS1	3.22e-05	19	185	4	PS00178
Domain	ARM-type_fold	USP34 GBF1 IPO8 IPO7 USP24 CKAP5 ZYG11B ARMC9 PPP4R4 RANBP17 MROH8 CEBPZ TNPO3	3.48e-05	339	185	13	IPR016024
Domain	Rossmann-like_a/b/a_fold	MARS1 WARS2 YARS1 CRY2 QARS1	6.41e-05	43	185	5	IPR014729
Domain	-	MARS1 WARS2 YARS1 CRY2 QARS1	6.41e-05	43	185	5	3.40.50.620
Domain	CHN1/CHN2	CHN1 CHN2	9.76e-05	2	185	2	IPR017356
Domain	RICIN	MRC1 GALNT7 PLA2R1 MRC2	1.58e-04	28	185	4	SM00458
Domain	RICIN_B_LECTIN	MRC1 GALNT7 PLA2R1 MRC2	1.58e-04	28	185	4	PS50231
Domain	Ricin_B_lectin	MRC1 GALNT7 PLA2R1 MRC2	2.09e-04	30	185	4	IPR000772
Domain	-	MRC1 PLA2R1 MRC2	2.54e-04	13	185	3	2.10.10.10
Domain	Cse1	IPO8 IPO7	2.91e-04	3	185	2	PF08506
Domain	Cse1	IPO8 IPO7	2.91e-04	3	185	2	IPR013713
Domain	Lactamase_B_6	INTS9 CPSF2	2.91e-04	3	185	2	PF16661
Domain	FN_type2_col-bd	MRC1 PLA2R1 MRC2	3.21e-04	14	185	3	IPR000562
Domain	FN2_2	MRC1 PLA2R1 MRC2	3.21e-04	14	185	3	PS51092
Domain	FN2_1	MRC1 PLA2R1 MRC2	3.21e-04	14	185	3	PS00023
Domain	fn2	MRC1 PLA2R1 MRC2	3.21e-04	14	185	3	PF00040
Domain	FN2	MRC1 PLA2R1 MRC2	3.21e-04	14	185	3	SM00059
Domain	Neurexin-like	CADM4 CADM2 NRXN2	3.21e-04	14	185	3	IPR003585
Domain	4.1m	CADM4 CADM2 NRXN2	3.21e-04	14	185	3	SM00294
Domain	PH_dom-like	MAPK8IP1 EPS8 FRS2 ECT2L BCR CERT1 ARHGEF10L EXOC8 JAK3 TBC1D1 AKAP13 ARHGEF26 MAPK8IP2	3.37e-04	426	185	13	IPR011993
Domain	IBN_N	IPO8 IPO7 RANBP17	3.99e-04	15	185	3	PF03810
Domain	DH_1	ECT2L BCR ARHGEF10L AKAP13 ARHGEF26	3.99e-04	63	185	5	PS00741
Domain	IBN_N	IPO8 IPO7 RANBP17	4.87e-04	16	185	3	SM00913
Domain	-	MAPK8IP1 EPS8 FRS2 ECT2L BCR CERT1 ARHGEF10L EXOC8 TBC1D1 AKAP13 ARHGEF26 MAPK8IP2	5.42e-04	391	185	12	2.30.29.30
Domain	RhoGEF	ECT2L BCR ARHGEF10L AKAP13 ARHGEF26	5.68e-04	68	185	5	SM00325
Domain	aa-tRNA-synth_Ic	WARS2 YARS1	5.78e-04	4	185	2	IPR002305
Domain	Beta-Casp	INTS9 CPSF2	5.78e-04	4	185	2	SM01027
Domain	Beta-Casp	INTS9 CPSF2	5.78e-04	4	185	2	PF10996
Domain	tRNA-synt_1b	WARS2 YARS1	5.78e-04	4	185	2	PF00579
Domain	Beta_Casp	INTS9 CPSF2	5.78e-04	4	185	2	IPR022712
Domain	Importin-beta_N	IPO8 IPO7 RANBP17	5.87e-04	17	185	3	IPR001494
Domain	PTB	MAPK8IP1 EPS8 TBC1D1 MAPK8IP2	6.45e-04	40	185	4	SM00462
Domain	RhoGEF	ECT2L BCR ARHGEF10L AKAP13 ARHGEF26	6.49e-04	70	185	5	PF00621
Domain	DH_2	ECT2L BCR ARHGEF10L AKAP13 ARHGEF26	6.49e-04	70	185	5	PS50010
Domain	-	ECT2L BCR ARHGEF10L AKAP13 ARHGEF26	6.93e-04	71	185	5	1.20.900.10
Domain	DH-domain	ECT2L BCR ARHGEF10L AKAP13 ARHGEF26	6.93e-04	71	185	5	IPR000219
Domain	PTB/PI_dom	MAPK8IP1 EPS8 TBC1D1 MAPK8IP2	7.09e-04	41	185	4	IPR006020
Domain	PX	SNX4 PXK SNX14 SNX5	9.28e-04	44	185	4	SM00312
Domain	PX	SNX4 PXK SNX14 SNX5	1.39e-03	49	185	4	PF00787
Domain	PX	SNX4 PXK SNX14 SNX5	1.50e-03	50	185	4	PS50195
Domain	-	SNX4 PXK SNX14 SNX5	1.62e-03	51	185	4	3.30.1520.10
Domain	-	IPO8 IPO7 CKAP5 ZYG11B ARMC9 PPP4R4 RANBP17 TNPO3	1.70e-03	222	185	8	1.25.10.10
Domain	Phox	SNX4 PXK SNX14 SNX5	1.74e-03	52	185	4	IPR001683
Pathway	BIOCARTA_CIRCADIAN_PATHWAY	PER1 CLOCK CRY2	2.08e-05	6	145	3	M22067
Pathway	BIOCARTA_CIRCADIAN_PATHWAY	PER1 CLOCK CRY2	3.62e-05	7	145	3	MM1578
Pathway	KEGG_AMINOACYL_TRNA_BIOSYNTHESIS	MARS1 WARS2 YARS1 PARS2 QARS1	5.98e-05	41	145	5	M14691
Pathway	REACTOME_TRNA_AMINOACYLATION	MARS1 WARS2 YARS1 PARS2 QARS1	6.73e-05	42	145	5	M456
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	SLC12A6 MAPK8IP1 EPS8 VPS18 RPLP1 MAP4K3 MARS1 NPEPPS CKAP5 POR SRP72 YTHDC2 CHD3 WDR37 BCR CADM2 YARS1 TBC1D24 TUBB3 HSPA12A FBXL16 NRXN2 PTPRZ1 IGHG1 DLG2 SLC4A4 DNAH6 MAPK8IP2 EXOC4	1.06e-09	1431	189	29	37142655
Pubmed	The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.	ZNF597 USP34 GBF1 IPO8 IPO7 DSC1 MARS1 CADM4 CKAP5 POR LAMP1 ZNF407 GALNT7 TBL3 TBC1D24 EXOC8 NCOR2 NKD1 CEBPZ MRC2 QARS1 TNPO3 EXOC4	1.87e-07	1203	189	23	29180619
Pubmed	The E3 ubiquitin ligase and RNA-binding protein ZNF598 orchestrates ribosome quality control of premature polyadenylated mRNAs.	IPO8 IPO7 DSC1 MARS1 STK38 CKAP5 POR LAMP1 IGHG1 QARS1 STK38L TNPO3	2.13e-07	320	189	12	28685749
Pubmed	The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cells.	USP34 EPS8 IPO7 USP24 SRP72 CHD3 CLOCK TUBB3 C1QBP INTS9 TNPO3	4.69e-07	282	189	11	23667531
Pubmed	∆F508 CFTR interactome remodelling promotes rescue of cystic fibrosis.	A2M IPO8 IPO7 DSC1 RPLP1 ERAP1 MARS1 NPEPPS LAMP1 ZYG11B EXOC8 TUBB3 C1QBP QARS1 TNPO3 EXOC4	5.79e-07	647	189	16	26618866
Pubmed	A role for the circadian clock protein Per1 in the regulation of aldosterone levels and renal Na+ retention.	PER1 CLOCK CRY2	6.29e-07	4	189	3	24154698
Pubmed	Characterization of the EGFR interactome reveals associated protein complex networks and intracellular receptor dynamics.	GBF1 IPO8 IPO7 MARS1 EXOC8 TUBB3 IGHG1 TNPO3 EXOC4	7.87e-07	183	189	9	23956138
Pubmed	Mutation of ARHGAP9 in patients with coronary spastic angina.	CHN2 BCR ARHGEF10L DLC1 AKAP13	1.95e-06	38	189	5	19911011
Pubmed	Phosphorylation of clock protein PER1 regulates its circadian degradation in normal human fibroblasts.	PER1 CLOCK CRY2	3.12e-06	6	189	3	14750904
Pubmed	Interacting molecular loops in the mammalian circadian clock.	PER1 CLOCK CRY2	3.12e-06	6	189	3	10807566
Pubmed	The role of polymorphisms in circadian pathway genes in breast tumorigenesis.	PER1 CLOCK CRY2	3.12e-06	6	189	3	20978934
Pubmed	Molecular assembly of the period-cryptochrome circadian transcriptional repressor complex.	PER1 CLOCK CRY2	3.12e-06	6	189	3	25127877
Pubmed	Rhythmic PER abundance defines a critical nodal point for negative feedback within the circadian clock mechanism.	PER1 CLOCK CRY2	3.12e-06	6	189	3	19917250
Pubmed	Analysis of the molecular pathophysiology of sleep disorders relevant to a disturbed biological clock.	PER1 CLOCK CRY2	5.44e-06	7	189	3	23546644
Pubmed	Differential maturation of circadian rhythms in clock gene proteins in the suprachiasmatic nucleus and the pars tuberalis during mouse ontogeny.	PER1 CLOCK CRY2	5.44e-06	7	189	3	19222558
Pubmed	α2-chimaerin controls neuronal migration and functioning of the cerebral cortex through CRMP-2.	CHN1 CHN2 TUBB3	5.44e-06	7	189	3	22138645
Pubmed	The polycomb group protein EZH2 is required for mammalian circadian clock function.	PER1 CLOCK CRY2	5.44e-06	7	189	3	16717091
Pubmed	Transcriptional architecture and chromatin landscape of the core circadian clock in mammals.	PER1 CLOCK CRY2	5.44e-06	7	189	3	22936566
Pubmed	Clock gene expression in gravid uterus and extra-embryonic tissues during late gestation in the mouse.	PER1 CLOCK CRY2	5.44e-06	7	189	3	20450826
Pubmed	Nuclear receptor HNF4A transrepresses CLOCK:BMAL1 and modulates tissue-specific circadian networks.	PER1 CLOCK CRY2	5.44e-06	7	189	3	30530698
Pubmed	Dec1 and Dec2 are regulators of the mammalian molecular clock.	PER1 CLOCK CRY2	5.44e-06	7	189	3	12397359
Pubmed	BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.	IPO7 MARS1 USP24 STK38 CKAP5 FRS2 SRP72 YTHDC2 FAM171A1 BUB1B C1QBP QARS1 ARHGEF26 EPHA3 EXOC4	8.54e-06	708	189	15	39231216
Pubmed	Machine learning helps identify CHRONO as a circadian clock component.	PER1 CLOCK CRY2	8.67e-06	8	189	3	24737000
Pubmed	Expression of the gene for Dec2, a basic helix-loop-helix transcription factor, is regulated by a molecular clock system.	PER1 CLOCK CRY2	8.67e-06	8	189	3	15147242
Pubmed	Involvement of posttranscriptional regulation of Clock in the emergence of circadian clock oscillation during mouse development.	PER1 CLOCK CRY2	8.67e-06	8	189	3	28827343
Pubmed	Kelch Domain of Gigaxonin Interacts with Intermediate Filament Proteins Affected in Giant Axonal Neuropathy.	DNHD1 MAP4K3 ZNF618 STK38 TUBB3 CEBPZ SYNE2 DNAH6	9.12e-06	187	189	8	26460568
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	USP34 GBF1 SPEG PER1 BCR RYR1 TBC1D9 ARHGEF10L TBC1D24 JAK3 NCOR2 BTBD7 RAB43 NADK AKAP13 ATG9A TNPO3 MED13 IQCE	1.05e-05	1105	189	19	35748872
Pubmed	SPATA2 Links CYLD to LUBAC, Activates CYLD, and Controls LUBAC Signaling.	IPO8 DSC1 RPLP1 MARS1 ACO1 STK38 E2F7 TUBB3 IGHG1 KRT77 C1QBP QARS1 STK38L	1.29e-05	558	189	13	27591049
Pubmed	Direct association between mouse PERIOD and CKIepsilon is critical for a functioning circadian clock.	PER1 CLOCK CRY2	1.30e-05	9	189	3	14701732
Pubmed	A directed protein interaction network for investigating intracellular signal transduction.	A2M EPS8 RPLP1 MARS1 CADM4 POR TSEN54 CHD3 CHN1 ADAMTS10 TUBB3 FBXL16 NRXN2 CEBPZ SYNE2 ATG9A QARS1 MAPK8IP2 SNX5	1.33e-05	1124	189	19	21900206
Pubmed	The variant rs1867277 in FOXE1 gene confers thyroid cancer susceptibility through the recruitment of USF1/USF2 transcription factors.	ACHE TSHR NCOR2 PLA2R1 DIO1 MED13	1.75e-05	99	189	6	19730683
Pubmed	Suggestive evidence for association of the circadian genes PERIOD3 and ARNTL with bipolar disorder.	PER1 CLOCK CRY2	1.84e-05	10	189	3	16528748
Pubmed	Testing the circadian gene hypothesis in prostate cancer: a population-based case-control study.	PER1 CLOCK CRY2	1.84e-05	10	189	3	19934327
Pubmed	A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.	SLC12A6 NRIP1 COL12A1 IPO7 ACO1 SRP72 ZNF407 NEB RYR1 SYNE2 MED13 SNX5	1.97e-05	497	189	12	23414517
Pubmed	Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	NTNG1 WDR37 NRXN2 SYNE2 TMEM131L STK38L	2.08e-05	102	189	6	10231032
Pubmed	Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	ZNF407 ZYG11B DLC1 KIAA1755 DNAH6 EXOC4	2.08e-05	102	189	6	11214970
Pubmed	A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.	SLC12A6 EPS8 MAP4K3 CADM4 FRS2 WDR37 TBC1D24 FAM171A1 HSPA12A EPHA3 EXOC4	2.14e-05	421	189	11	36976175
Pubmed	Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci.	MSH5 PXK TNPO3	2.52e-05	11	189	3	18204446
Pubmed	Oligomerization of the macrophage mannose receptor enhances gp120-mediated binding of HIV-1.	MRC1 MRC2	2.94e-05	2	189	2	19224860
Pubmed	NDR functions as a physiological YAP1 kinase in the intestinal epithelium.	STK38 STK38L	2.94e-05	2	189	2	25601544
Pubmed	Chlamydia trachomatis co-opts GBF1 and CERT to acquire host sphingomyelin for distinct roles during intracellular development.	GBF1 CERT1	2.94e-05	2	189	2	21909260
Pubmed	Mannose receptor regulation of macrophage cell migration.	MRC1 MRC2	2.94e-05	2	189	2	17596337
Pubmed	Rare variants in methionyl- and tyrosyl-tRNA synthetase genes in late-onset autosomal dominant Charcot-Marie-Tooth neuropathy.	MARS1 YARS1	2.94e-05	2	189	2	24354524
Pubmed	Engagement of the mannose receptor by tumoral mucins activates an immune suppressive phenotype in human tumor-associated macrophages.	MRC1 MUC16	2.94e-05	2	189	2	21331365
Pubmed	EphA3 promotes the proliferation of NPC cells through negatively regulating the ability of FOG2.	ZFPM2 EPHA3	2.94e-05	2	189	2	32633364
Pubmed	Male-biased aganglionic megacolon in the TashT mouse model of Hirschsprung disease involves upregulation of p53 protein activity and Ddx3y gene expression.	ACHE TUBB3	2.94e-05	2	189	2	32898154
Pubmed	Opposing actions of Per1 and Cry2 in the regulation of Per1 target gene expression in the liver and kidney.	PER1 CRY2	2.94e-05	2	189	2	23824961
Pubmed	Association of human mannose receptor in sexual transmission of human immunodeficiency virus in serodiscordant couples.	MRC1 MRC2	2.94e-05	2	189	2	23148569
Pubmed	CD4-independent infection of astrocytes by human immunodeficiency virus type 1: requirement for the human mannose receptor.	MRC1 MRC2	2.94e-05	2	189	2	15047828
Pubmed	Clock-dependent and independent transcriptional control of the two isoforms from the mouse Rorgamma gene.	CLOCK RORC	2.94e-05	2	189	2	19076641
Pubmed	No circadian rhythms in testis: Period1 expression is clock independent and developmentally regulated in the mouse.	PER1 CLOCK	2.94e-05	2	189	2	12511614
Pubmed	Discovery of Novel Agents on Spindle Assembly Checkpoint to Sensitize Vinorelbine-Induced Mitotic Cell Death Against Human Non-Small Cell Lung Cancers.	BUB1B PDE5A	2.94e-05	2	189	2	32764382
Pubmed	Requirement of JIP scaffold proteins for NMDA-mediated signal transduction.	MAPK8IP1 MAPK8IP2	2.94e-05	2	189	2	17875667
Pubmed	Signal transduction cross talk mediated by Jun N-terminal kinase-interacting protein and insulin receptor substrate scaffold protein complexes.	MAPK8IP1 MAPK8IP2	2.94e-05	2	189	2	19564410
Pubmed	Low CLOCK and CRY2 in 2nd trimester human maternal blood and risk of preterm birth: a nested case-control study†.	CLOCK CRY2	2.94e-05	2	189	2	34142702
Pubmed	Noninfectious entry of HIV-1 into peripheral and brain macrophages mediated by the mannose receptor.	MRC1 MRC2	2.94e-05	2	189	2	17360361
Pubmed	Clock controls circadian period in isolated suprachiasmatic nucleus neurons.	PER1 CLOCK	2.94e-05	2	189	2	10196587
Pubmed	Mitochondrial Protein Synthesis Is Essential for Terminal Differentiation of CD45- TER119-Erythroid and Lymphoid Progenitors.	C1QBP COMMD10	2.94e-05	2	189	2	33103089
Pubmed	The phosphatidylinositol 3-phosphate-binding protein SNX4 controls ATG9A recycling and autophagy.	SNX4 ATG9A	2.94e-05	2	189	2	33468622
Pubmed	Microcurrent stimulation activates the circadian machinery in mice.	PER1 CLOCK	2.94e-05	2	189	2	30944082
Pubmed	uPARAP/endo180 directs lysosomal delivery and degradation of collagen IV.	LAMP1 MRC2	2.94e-05	2	189	2	14729061
Pubmed	HIV-1 Tat represses transcription from the mannose receptor promoter.	MRC1 MRC2	2.94e-05	2	189	2	11120831
Pubmed	Mitochondrial Reactive Oxygen Species Are Essential for the Development of Psoriatic Inflammation.	C1QBP COMMD10	2.94e-05	2	189	2	34421919
Pubmed	The mannose receptor on murine liver sinusoidal endothelial cells is the main denatured collagen clearance receptor.	MRC1 MRC2	2.94e-05	2	189	2	17518370
Pubmed	Prognostic significance of serum chemerin levels in patients with non-small cell lung cancer.	CHN1 CHN2	2.94e-05	2	189	2	28160556
Pubmed	Structural basis of homodimerization of the JNK scaffold protein JIP2 and its heterodimerization with JIP1.	MAPK8IP1 MAPK8IP2	2.94e-05	2	189	2	39013462
Pubmed	Identification of new human cadherin genes using a combination of protein motif search and gene finding methods.	DCHS2 FAT4	2.94e-05	2	189	2	15003449
Pubmed	Polymorphisms in the novel serotonin receptor subunit gene HTR3C show different risks for acute chemotherapy-induced vomiting after anthracycline chemotherapy.	HTR3C HTR3B	2.94e-05	2	189	2	18389280
Pubmed	BubR1 Insufficiency Impairs Liver Regeneration in Aged Mice after Hepatectomy through Intercalated Disc Abnormality.	DSC1 BUB1B	2.94e-05	2	189	2	27561386
Pubmed	Differential roles of JIP scaffold proteins in the modulation of amyloid precursor protein metabolism.	MAPK8IP1 MAPK8IP2	2.94e-05	2	189	2	12023290
Pubmed	Lethal multiple pterygium syndrome, large cystic hygroma, and cleft palate: Rare and severe fetal presentations of RYR1- and NEB-related congenital myopathies.	NEB RYR1	2.94e-05	2	189	2	38520674
Pubmed	Regulation of NDR2 protein kinase by multi-site phosphorylation and the S100B calcium-binding protein.	STK38 STK38L	2.94e-05	2	189	2	15037617
Pubmed	Histone acetyltransferase-dependent chromatin remodeling and the vascular clock.	PER1 CLOCK CRY2	3.35e-05	12	189	3	14645221
Pubmed	Proteomic identification of common SCF ubiquitin ligase FBXO6-interacting glycoproteins in three kinds of cells.	A2M IPO7 MARS1 NPEPPS STK38 CKAP5 LAMP1 TUBB3 MRC2 C1QBP TMEM131L STK38L TCTN2	3.42e-05	613	189	13	22268729
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	USP34 GBF1 HDAC5 ERAP1 NRXN2 TBC1D1 SYNE2 STK38L	3.45e-05	225	189	8	12168954
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	USP34 WDR37 BCR CLOCK ARHGEF10L TBC1D24 NRXN2 MRC2 TMEM131L CPSF2 MED13 IQCE	3.61e-05	529	189	12	14621295
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	EPS8 GBF1 HDAC5 FBXL16 ACAD11 TBC1D1 C1QBP NADK QARS1 STK38L SNX5	3.63e-05	446	189	11	24255178
Pubmed	Clock genes may influence bipolar disorder susceptibility and dysfunctional circadian rhythm.	PER1 CLOCK CRY2	4.34e-05	13	189	3	18228528
Pubmed	A molecular mechanism for circadian clock negative feedback.	PER1 CLOCK CRY2	4.34e-05	13	189	3	21680841
Pubmed	Hepatitis B Virus HBx Protein Mediates the Degradation of Host Restriction Factors through the Cullin 4 DDB1 E3 Ubiquitin Ligase Complex.	GBF1 DSC1 ERAP1 MARS1 CKAP5 SRP72 PPP4R4 FCSK EXOC4	4.69e-05	304	189	9	32235678
Pubmed	Deubiquitinating enzyme PSMD14 promotes tumor metastasis through stabilizing SNAIL in human esophageal squamous cell carcinoma.	IPO8 IPO7 RPLP1 NPEPPS STK38 E2F7 YARS1 TUBB3 C1QBP STK38L	5.13e-05	383	189	10	29331416
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	NRIP1 FAT4 IPO7 HBEGF USP24 MUC16 NEB TBL3 RYR1 PPP4R4 NCOR2 ACAD11 SYNE2	5.14e-05	638	189	13	31182584
Pubmed	MET Inhibitors Promote Liver Tumor Evasion of the Immune Response by Stabilizing PDL1.	IPO7 ERAP1 MARS1 NPEPPS SRP72 YARS1 QARS1	6.57e-05	182	189	7	30711629
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	SLC12A6 NRIP1 MARS1 NPEPPS CHD3 MSH5 GALNT7 WDR37 BCR CERT1 PPP4R4 RANBP17 NCOR2 GUCY1A1 TBC1D1 AKAP13 STK38L ARHGEF26 DOP1A EXOC4 KLHL26	6.59e-05	1489	189	21	28611215
Pubmed	Dynamic circadian protein-protein interaction networks predict temporal organization of cellular functions.	PER1 CLOCK CRY2 RORC	6.62e-05	40	189	4	23555304
Pubmed	Prokineticin 2 transmits the behavioural circadian rhythm of the suprachiasmatic nucleus.	PER1 CLOCK CRY2	6.85e-05	15	189	3	12024206
Pubmed	SARS-CoV-2 Nsp6 damages Drosophila heart and mouse cardiomyocytes through MGA/MAX complex-mediated increased glycolysis.	GBF1 IPO8 IPO7 MARS1 CKAP5 YARS1 TBC1D9 EXOC8 ATG9A QARS1 STK38L TNPO3 EXOC4	6.91e-05	657	189	13	36180527
Pubmed	Integrative analysis of kinase networks in TRAIL-induced apoptosis provides a source of potential targets for combination therapy.	IPO7 RPLP1 MAP4K3 STK38 PXK JAK3 BUB1B C1QBP STK38L ARHGEF26	7.51e-05	401	189	10	25852190
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	GBF1 CKAP5 BCR PPP4R4 FAM171A1 DLC1 TBC1D1 KRT77 SYNE2 BUB1B NADK AKAP13 TNPO3 DOP1A EXOC4	8.02e-05	861	189	15	36931259
Pubmed	PER2 variantion is associated with depression vulnerability.	PER1 CLOCK CRY2	8.40e-05	16	189	3	19693801
Pubmed	Genetic associations and functional characterization of M1 aminopeptidases and immune-mediated diseases.	ERAP1 NPEPPS	8.78e-05	3	189	2	25142031
Pubmed	Human NDR kinases control G(1)/S cell cycle transition by directly regulating p21 stability.	STK38 STK38L	8.78e-05	3	189	2	21262772
Pubmed	SH3BP1, an exocyst-associated RhoGAP, inactivates Rac1 at the front to drive cell motility.	EXOC8 EXOC4	8.78e-05	3	189	2	21658605
Pubmed	Chaperone stress 70 protein (STCH) binds and regulates two acid/base transporters NBCe1-B and NHE1.	SLC9A1 SLC4A4	8.78e-05	3	189	2	23303189
Pubmed	Cyclin D1 promotes cell cycle progression through enhancing NDR1/2 kinase activity independent of cyclin-dependent kinase 4.	STK38 STK38L	8.78e-05	3	189	2	23897809
Pubmed	Distribution of murine mannose receptor expression from early embryogenesis through to adulthood.	MRC1 MRC2	8.78e-05	3	189	2	9560474
Pubmed	Antisense-Induced Downregulation of Clock Genes in the Shell Region of the Nucleus Accumbens Reduces Binge Drinking in Mice.	PER1 CLOCK	8.78e-05	3	189	2	33606281
Pubmed	Disruption of clock gene expression in human colorectal liver metastases.	PER1 CLOCK	8.78e-05	3	189	2	27492458
Pubmed	Roles of CLOCK phosphorylation in suppression of E-box-dependent transcription.	CLOCK CRY2	8.78e-05	3	189	2	19414601
Pubmed	Prominent expression of FRS2beta protein in neural cells and its association with intracellular vesicles.	FRS2 TUBB3	8.78e-05	3	189	2	19187780
GeneFamily	Aminoacyl tRNA synthetases, Class I	MARS1 WARS2 YARS1 QARS1	9.38e-06	19	131	4	131
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	ECT2L BCR ARHGEF10L AKAP13 ARHGEF26	1.16e-04	66	131	5	722
GeneFamily	Armadillo repeat containing\|Importins	IPO8 IPO7 TNPO3	2.80e-04	18	131	3	596
GeneFamily	5-hydroxytryptamine receptors, ionotropic	HTR3C HTR3B	5.14e-04	5	131	2	172
GeneFamily	Sorting nexins\|PX-BAR domain containing	SNX4 SNX14 SNX5	1.18e-03	29	131	3	754
GeneFamily	Exocyst complex	EXOC8 EXOC4	1.81e-03	9	131	2	1055
GeneFamily	G protein-coupled receptors, Class A orphans	GPR20 MAS1 GPR132 GPR176	2.48e-03	78	131	4	262
GeneFamily	Sorting nexins\|PX-BAR domain containing	SNX4 SNX5	3.28e-03	12	131	2	1290
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HGABA	SPEG STK32B NTNG1 ZYG11B CHD3 GRIK3 NEB CHN1 CPNE5 CHN2 CERT1 PXK CADM2 TBC1D9 ZFPM2 TBC1D24 TUBB3 HSPA12A FBXL16 NRXN2 GUCY1A1 DLG2 GPR176 MAPK8IP2 DOP1A EPHA3	1.06e-07	1106	188	26	M39071
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	USP34 EPS8 NRIP1 SNX4 GBF1 IPO7 NPEPPS USP24 CKAP5 WDR37 CLOCK FAM171A1 NCOR2 DLC1 SYNE2 BUB1B TMEM131L AKAP13 MED13	1.40e-05	856	188	19	M4500
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	A2M COL12A1 GPR20 SPEG ZFPM2 DLC1 NKD1 GUCY1A1 MRC2 TMEM131L KIAA1755 PDE5A	3.38e-11	190	188	12	70c86dd454afb21d4a85db56c5f369d4b342bc97
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	A2M EPS8 FAT4 COL12A1 ZFPM2 DLC1 PTPRZ1 MRC2 GPR176 EPHA3	4.24e-09	176	188	10	9bc87cd5cda2372e1bce94c9dfd408eb1dfd8d0c
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	A2M EPS8 FAT4 COL12A1 ZFPM2 DLC1 PTPRZ1 MRC2 GPR176 EPHA3	4.24e-09	176	188	10	3f8274a7ab67f9f8a8923193763a5543cfe4defa
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	A2M EPS8 COL12A1 GPR20 SPEG ZFPM2 DLC1 NKD1 TMEM131L PDE5A	1.19e-08	196	188	10	b8759e6231e0254797d6c30930407b79440c57bb
ToppCell	droplet-Kidney-nan-18m-Epithelial-Pecam____kidney_capillary_endothelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT4 PCDHGA11 SPEG PLA2R1 GUCY1A1 MRC2 MSS51 ARHGEF26 EPHA3	4.50e-08	169	188	9	87116c33c5ca8cb1862e103e5607b1df4d264569
ToppCell	RA-13._Vascular_Smooth_Muscle\|RA / Chamber and Cluster_Paper	A2M GPR20 SPEG DLC1 NKD1 GUCY1A1 TBC1D1 PDE5A GPR176	8.91e-08	183	188	9	818fd886e0188091310825f9145fa53328f2c979
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	A2M FAT4 COL12A1 ABCA12 GRIK3 NEB CADM2 NRK SLC4A4	9.34e-08	184	188	9	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	A2M FAT4 COL12A1 ABCA12 GRIK3 NEB CADM2 NRK SLC4A4	9.34e-08	184	188	9	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	A2M FAT4 COL12A1 ABCA12 GRIK3 NEB CADM2 NRK SLC4A4	9.34e-08	184	188	9	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	A2M GPR20 SPEG ZFPM2 DLC1 NKD1 TBC1D1 TMEM131L PDE5A	1.47e-07	194	188	9	5c3b2b05d1e4f146551fe4c920263d8e6ca34de3
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	A2M GPR20 SPEG ZFPM2 DLC1 NKD1 TBC1D1 TMEM131L PDE5A	1.47e-07	194	188	9	ab9cad697f9209d2889bc02b43b502dfeb2ebfef
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	A2M COL12A1 GPR20 SPEG ZFPM2 DLC1 NKD1 TMEM131L PDE5A	1.47e-07	194	188	9	ebb038f94f49f5c655578d1b018676e10c6b7e3c
ToppCell	droplet-Limb_Muscle-MUSCLE-1m-Mesenchymal-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR20 SPEG CHN1 BCR CRY2 NKD1 GUCY1A1 PDE5A STK38L	1.53e-07	195	188	9	0bdf845939bc4b8cc94f2808aea60f818425b076
ToppCell	Sepsis-ICU-NoSEP-Lymphocyte-T/NK-Treg\|ICU-NoSEP / Disease, condition lineage and cell class	MAPK8IP1 CACNA1D CHN1 HELB JAK3 FBXL16 SYNE2 ILDR1 MSS51	1.74e-07	198	188	9	1ed4dfe5565328cb0f7ef31e6b2f67dfbdf3e2ac
ToppCell	Pericytes-SSc-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	DCHS2 FTCD CHN1 ZFPM2 HSPA12A NKD1 PDE5A GPR176	1.06e-06	181	188	8	35c470988a93381eefa300831aabb813fa1b90bd
ToppCell	RA-13._Vascular_Smooth_Muscle\|World / Chamber and Cluster_Paper	A2M GPR20 DLC1 NKD1 TBC1D1 PDE5A STK38L GPR176	1.15e-06	183	188	8	cae2ee08f985a6f005b4b8e959e465350315156a
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	A2M GPR20 SPEG DLC1 NKD1 TBC1D1 TMEM131L PDE5A	1.46e-06	189	188	8	7fbe855bfdb47d35e040b04a80fe4b729a3764e8
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	A2M GPR20 SPEG DLC1 NKD1 TBC1D1 TMEM131L PDE5A	1.46e-06	189	188	8	06b35abecd29f902cf251fcc1f6ad33db7ab08a2
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	GPR20 SPEG ZFPM2 DLC1 NKD1 TBC1D1 TMEM131L PDE5A	1.46e-06	189	188	8	127ad2ba3e794df8cce2eee3e4171bccb5aad51b
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	GPR20 SPEG ZFPM2 DLC1 NKD1 TBC1D1 TMEM131L PDE5A	1.46e-06	189	188	8	2cfb4d12f75678d1619f4743838a0e954bd57761
ToppCell	facs-Tongue-nan-3m-Epithelial-suprabasal\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DSC1 ABCA12 ARHGEF10L TUBB3 DLC1 DLG2 AKAP13 ADGRF4	1.52e-06	190	188	8	719a5cecc3e8001ca9c38165258b5ff9c800713a
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL12A1 ZFPM2 DLC1 NKD1 MRC2 KIAA1755 PDE5A EPHA3	1.58e-06	191	188	8	107113b930d9ad171f1b2aa20df4567c94fae7d8
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	A2M EPS8 COL12A1 GPR20 SPEG DLC1 GPR176 EPHA3	1.58e-06	191	188	8	04c4d454b57e29a8d1dcdeb4678ce71bdc29b77b
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL12A1 ZFPM2 DLC1 NKD1 MRC2 KIAA1755 PDE5A EPHA3	1.58e-06	191	188	8	bc353a79a1d11ca52bba5e3874a80d432e1a7715
ToppCell	COVID-19-Fibroblasts-Other_FB\|COVID-19 / group, cell type (main and fine annotations)	A2M CACNA1D FAT4 COL12A1 CHN1 ZFPM2 DLC1 DLG2	1.71e-06	193	188	8	e6b75be08e33c1de079fb5c02f0b4468128b369c
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2\|Adult / Lineage, Cell type, age group and donor	EPS8 SLC34A2 ARMC9 PPP4R4 DLC1 DLG2 SLC4A4 LRRC36	1.71e-06	193	188	8	738f4f0a9ddde2432b429ab46838e353b1790589
ToppCell	droplet-Limb_Muscle-MUSCLE-1m-Mesenchymal-smooth_muscle_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR20 SPEG CHN1 BCR NKD1 GUCY1A1 PDE5A STK38L	1.78e-06	194	188	8	b8a130ffae68ffe550bf335460a1ec1035cf8d8d
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	A2M COL12A1 ZFPM2 DLC1 NKD1 MRC2 ARHGEF26 EPHA3	1.84e-06	195	188	8	dd281a249854800f737dc22e0f375f66dfb5cf5f
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	A2M COL12A1 ZFPM2 DLC1 NKD1 MRC2 TMEM131L PDE5A	1.84e-06	195	188	8	edd4cd8402af81737b2074f9dce71cc6ab09be7e
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	A2M COL12A1 ZFPM2 DLC1 NKD1 MRC2 ARHGEF26 EPHA3	1.84e-06	195	188	8	49c99553629cdd83ee56a2e508d5bc8d34b8507b
ToppCell	COVID-19-lung-Pericytes/_Smooth_Muscle\|COVID-19 / Disease (COVID-19 only), tissue and cell type	A2M EPS8 GPR20 CHN1 DLC1 NKD1 GUCY1A1 PDE5A	1.92e-06	196	188	8	754a3613340932563cd8424d775e18b93c3a1aaa
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	A2M EPS8 FAT4 ZFPM2 DLC1 MRC2 KIAA1755 GPR176	1.99e-06	197	188	8	85a8f1d18e0dd1d31341f5131eecd217553bf042
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	A2M EPS8 FAT4 COL12A1 ZFPM2 DLC1 MRC2 GPR176	1.99e-06	197	188	8	9b480f9c799a244bfee64487abd8a1bf07c9a3a2
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	A2M EPS8 FAT4 ZFPM2 DLC1 MRC2 KIAA1755 GPR176	1.99e-06	197	188	8	e8e3ba791dfaa0fab35e0329a5e34376f9ee6143
ToppCell	PCW_13-14-Mesenchymal\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	CACNA1D FAT4 NTNG1 ZFPM2 GUCY1A1 MRC2 PDE5A SLC4A4	1.99e-06	197	188	8	73a2085d2682d636726a5432d572ae2a3fbe1c3f
ToppCell	TCGA-Kidney-Solid_Tissue_Normal-Kidney-Kidney_normal_tissue-5\|TCGA-Kidney / Sample_Type by Project: Shred V9	NTNG1 ASB15 PLA2R1 NKD1 HPD DIO1 MUC6	4.98e-06	158	188	7	34b284a62cc3fb90429ce579fd8cb8a60178091b
ToppCell	ICU-NoSEP-Lymphocyte-T_NK-Treg\|ICU-NoSEP / Disease, Lineage and Cell Type	MAPK8IP1 CHN1 JAK3 FBXL16 SYNE2 ILDR1 MSS51	5.19e-06	159	188	7	d065ec02a4f3672ba53d4fea66029f1ce68f367f
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TEX50 FPR1 TSHR CPNE5 RYR1 DTHD1 CCDC180	5.19e-06	159	188	7	00a157d033627d0e65c3fbd38d652c4cf56b47f6
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Neural-neural_cell-Schwann_Cell_/_Neural\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	GRIK3 CADM2 DLC1 PTPRZ1 KIAA1755 PDE5A ARHGEF26	5.41e-06	160	188	7	14dfa519e68bab4bce890ddb66fa7763f18d9f19
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Neural-neural_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	GRIK3 CADM2 DLC1 PTPRZ1 KIAA1755 PDE5A ARHGEF26	5.41e-06	160	188	7	839bbdfd4e4c7b48260c8bfb7670378634405e1d
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Neural\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	GRIK3 CADM2 DLC1 PTPRZ1 KIAA1755 PDE5A ARHGEF26	5.41e-06	160	188	7	5b7789d4668ed7732babedc32d812233b430e0bd
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Neural-neural_cell-Schwann_Cell_/_Neural-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	GRIK3 CADM2 DLC1 PTPRZ1 KIAA1755 PDE5A ARHGEF26	5.41e-06	160	188	7	bba1486faaad5299e10f4fe17c6d149c28dc2560
ToppCell	10x5'-blood-Lymphocytic_T_CD4-T_CD4/CD8\|blood / Manually curated celltypes from each tissue	USP34 SPEG HELB JAK3 SYNE2 TMEM131L EXOC4	5.87e-06	162	188	7	b4535bcb3f469bc139e73f1122f4070013e5a1de
ToppCell	droplet-Liver-Hepatocytes-21m-Epithelial-Hepatocyte_(Pericentral,_Midlobular,_Periportal)\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FTCD PRODH2 ACAD11 HPD DIO1 RORC SLC4A4	6.36e-06	164	188	7	90afae3cca108ebfb44ff2ec4adcbb8c68a0bdf2
ToppCell	LV-16._Neuronal\|World / Chamber and Cluster_Paper	GRIK3 CADM2 HSPA12A DLC1 PTPRZ1 ARHGEF26 MAPK8IP2	6.62e-06	165	188	7	6ed52cb756d21addf46c7f6c457458b01339fe04
ToppCell	facs-Skin-Anagen-24m-Epithelial-epidermal_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RARRES1 ABCA12 ACHE CPNE5 KRT77 DLG2 ADGRF4	7.17e-06	167	188	7	02c89069dcd0e87f7502e32b14e7cbd3cab81a09
ToppCell	E18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_prolif\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MAP4K3 ACHE HBEGF CHN1 GUCY1A1 TBC1D1 PDE5A	7.17e-06	167	188	7	b0eb7a40491dd2432f5282f578ce569df86d21a7
ToppCell	tumor_Lymph_Node_/_Brain-T/NK_cells-CD8+/CD4+_Mixed_Th\|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass	PER1 NEB CHN1 PARS2 TRAT1 TMEM131L GPR132	7.17e-06	167	188	7	c0c944eae0514dc8e00d0c2892a0792e157695ec
ToppCell	COVID-19-Heart-Neuronal\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CADM4 GRIK3 CADM2 HSPA12A DLC1 PTPRZ1 ARHGEF26	7.45e-06	168	188	7	88c2c574f428c2502b5fe099bd73b0758f668ef6
ToppCell	NS-critical-d_0-4-Epithelial-Secretory\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	RARRES1 ABCA12 SLC34A2 PARS2 ILDR1 ADGRF4 SLC4A4	7.75e-06	169	188	7	aec97583b23112060437b619cb429dc32f29285f
ToppCell	LV-16._Neuronal\|LV / Chamber and Cluster_Paper	GRIK3 CADM2 HSPA12A DLC1 PTPRZ1 ARHGEF26 MAPK8IP2	7.75e-06	169	188	7	a8fc8ab0f0757e939e213efb61c03cfe390bf7d2
ToppCell	facs-Skin-Skin_Anagen-18m-Epithelial-epidermal_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RARRES1 ACHE HBEGF CPNE5 HSPA12A KRT77 ADGRF4	9.02e-06	173	188	7	0f9c1d3298e59e6d22bb3306f0f445f490be8bbd
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ACO1 POR FTCD HHLA2 PRODH2 DIO1 SLC4A4	9.02e-06	173	188	7	8888434641ea554a9b62c436e87920378eef29cd
ToppCell	PND10-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2-AT1/AT2_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	HBEGF SLC34A2 TEX15 RANBP17 MRC2 CATSPER4 DLG2	9.73e-06	175	188	7	35fb7735dd3355476fe60404833cb60bd066bcf1
ToppCell	PND10-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	HBEGF SLC34A2 TEX15 RANBP17 MRC2 CATSPER4 DLG2	9.73e-06	175	188	7	442f261a3b2c4d2523f7d4089178f8c79cac2f0f
ToppCell	LPS-IL1RA+antiTNF\|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNA1D ZNF618 TMEM131L DLG2 AKAP13 ARHGEF26 EXOC4	1.05e-05	177	188	7	b7fee75de7e96924af488a5baa2334711889ae7c
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Neuronal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TEX50 FPR1 CPNE5 RYR1 HSPA12A FBXL16 MAPK8IP2	1.13e-05	179	188	7	a3922476f33d2e4137a12dbda21a1703dff79684
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CACNA1D MAP4K3 USP24 TBC1D9 FAM171A1 NRK TRPV6	1.13e-05	179	188	7	666072c0e8448dbaec1683d18368ec2502453f90
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SLC12A6 FTCD PRODH2 SYNE2 DIO1 DLG2 SLC4A4	1.17e-05	180	188	7	f8bdfd7bf7b3d52c659a29d8f5f80858e79da83e
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Neuronal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL12A1 CADM4 NTNG1 GRIK3 CADM2 TUBB3 PTPRZ1	1.17e-05	180	188	7	dad458398683ff80a6e207bdc08e257d1bb757d6
ToppCell	3'-GW_trimst-2-SmallIntestine-Neuronal-Glial_immature-Glia_1_(DHH+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HBEGF CADM4 GRIK3 CADM2 TUBB3 HSPA12A PTPRZ1	1.17e-05	180	188	7	38490017dd590e3fcfa7e88d8d15235d55f90cf1
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L3_RORB_CARTPT\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	NTNG1 PPP4R4 FFAR4 PLA2R1 TMEM131L SLC4A4 EPHA3	1.17e-05	180	188	7	5e78b29fa1cbdcf502fee3577e5b45766b90d1dc
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL12A1 CADM4 NTNG1 GRIK3 CADM2 TUBB3 PTPRZ1	1.17e-05	180	188	7	d9c9399df3e2d9f23dbbfffb6cbe8404bf01e2b7
ToppCell	Control-Epithelial_cells-AT2\|Control / group, cell type (main and fine annotations)	EPS8 SLC34A2 PPP4R4 DLC1 DLG2 SLC4A4 LRRC36	1.17e-05	180	188	7	198b19e7910b4a8cc7e820c525ab357c7f99f578
ToppCell	facs-Large_Intestine-Distal-3m-Epithelial-nan\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR20 SLC34A2 FFAR4 HPD RORC TPSG1 STK38L	1.17e-05	180	188	7	a0faed4cf23f6d5e6e8f6b0284cea8a5bd0680a0
ToppCell	RA-16._Neuronal\|RA / Chamber and Cluster_Paper	CADM4 GRIK3 CADM2 HSPA12A DLC1 PTPRZ1 ARHGEF26	1.17e-05	180	188	7	5842febfdabac61ce970254fb0ef17a628f1b8c0
ToppCell	RA-16._Neuronal\|World / Chamber and Cluster_Paper	CADM4 GRIK3 CADM2 HSPA12A DLC1 PTPRZ1 ARHGEF26	1.21e-05	181	188	7	7d22a43f887e0747f0cb87ba364ff27905ee6eec
ToppCell	facs-Heart-LV-3m-Mesenchymal-valve_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPS8 ACHE CHN1 PLA2R1 HSPA12A GUCY1A1 TBC1D1	1.21e-05	181	188	7	06174ce9240c9261c0f51a1b0d875335d60722e5
ToppCell	facs-Heart-LV-3m-Mesenchymal-valve_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPS8 ACHE CHN1 PLA2R1 HSPA12A GUCY1A1 TBC1D1	1.21e-05	181	188	7	1db1eb7d330a7e5090994007ae287e11f0a74450
ToppCell	droplet-Lung-LUNG-1m-Mesenchymal-Pericyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAPK8IP1 HBEGF ASB15 CHN1 BCR GUCY1A1 PDE5A	1.25e-05	182	188	7	aba4c06d5d7618ac21b2695bca8e7a1346a91090
ToppCell	droplet-Lung-LUNG-1m-Mesenchymal-pericyte_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAPK8IP1 HBEGF ASB15 CHN1 BCR GUCY1A1 PDE5A	1.25e-05	182	188	7	9edaccf1154cec92ca9a28e9b1f9075cfd422bfd
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL12A1 GUCY1A1 MRC2 NRK KIAA1755 DLG2 EPHA3	1.25e-05	182	188	7	3dfa9187e9d2bab1d199079d29209c4648220ada
ToppCell	facs-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l25-31\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CADM4 STK32B NTNG1 GRIK3 CADM2 TUBB3 PTPRZ1	1.25e-05	182	188	7	a1c0e4090a9e7aa4941a40c817d178de144888b6
ToppCell	droplet-Liver-Npc-21m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MRC1 ACHE ZFPM2 FAM171A1 PLA2R1 NKD1 NRXN2	1.25e-05	182	188	7	b1ec2015aad1181eac1bbf8d48ad6f2f7ed24a01
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	EPS8 SLC34A2 DLC1 GUCY1A1 DLG2 SLC4A4 LRRC36	1.30e-05	183	188	7	6847c1252d6bb105524f812658112517fd351eab
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	EPS8 COL12A1 SPEG ZFPM2 DLC1 NKD1 EPHA3	1.30e-05	183	188	7	667717366cb181b8a04a347e64f0f5a4dfc6ee7f
ToppCell	facs-Skin-Telogen-3m-Epithelial-epidermal_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RARRES1 ABCA12 ACHE GALNT7 KRT77 DLG2 ADGRF4	1.30e-05	183	188	7	ed1e0b07475f9951728682ed70b85367cf2a744d
ToppCell	facs-Lung-EPCAM-24m-Mesenchymal-Pericyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HBEGF CHN1 FCSK TUBB3 GUCY1A1 PTPRZ1 PDE5A	1.30e-05	183	188	7	0e8fb371d8eac777451c76f41d53577f5dfb740d
ToppCell	facs-Lung-EPCAM-24m-Mesenchymal-pericyte_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HBEGF CHN1 FCSK TUBB3 GUCY1A1 PTPRZ1 PDE5A	1.30e-05	183	188	7	cbc3b00faa7e4e0dbbbc8ee105467c65241c7470
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL12A1 CADM4 NTNG1 GRIK3 CADM2 PTPRZ1 MSS51	1.30e-05	183	188	7	8330c39184ce076e1f95fd3725b68af551d89db0
ToppCell	droplet-Lung-1m-Mesenchymal-myofibroblast-pericyte_cell-pericyte\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MAPK8IP1 ACHE HBEGF ASB15 CHN1 GUCY1A1 PDE5A	1.35e-05	184	188	7	4cb5f299dd7413e0be1ad7af817ee614b23a18ae
ToppCell	wk_20-22-Epithelial-PNS-intermediate_Schwann\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	CADM4 GRIK3 CADM2 HSPA12A KIAA1755 ARHGEF26 MED13	1.35e-05	184	188	7	4e3ba64692868563a579902aa9c6f88cab5bce26
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CPNE5 CHN2 TMEM244 GUCY1A1 TRPV6 DNAH6 EPHA3	1.35e-05	184	188	7	ca35a3d2b536c8b2bf5c4d635605e5a3ae94a428
ToppCell	droplet-Lung-1m-Mesenchymal-myofibroblast-pericyte_cell\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MAPK8IP1 ACHE HBEGF ASB15 CHN1 GUCY1A1 PDE5A	1.35e-05	184	188	7	39bb0eb55bdc2cea46e41c7f21d8c5883f14e6bd
ToppCell	droplet-Kidney-KIDNEY-1m-Epithelial-Pecam____kidney_capillary_endothelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RARRES1 SPEG PLA2R1 GUCY1A1 MRC2 ARHGEF26 EPHA3	1.35e-05	184	188	7	1c857126c0ea0671f0d60b048efca288d348d653
ToppCell	COVID-19-Fibroblasts-Adventitial_FB\|COVID-19 / group, cell type (main and fine annotations)	A2M RARRES1 ZFPM2 DLC1 KIAA1755 DLG2 EPHA3	1.39e-05	185	188	7	a5aebf2b9b05b550d021272731d68af9a6b1229d
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	A2M EPS8 COL12A1 GPR20 DLC1 GUCY1A1 TMEM131L	1.39e-05	185	188	7	51dfe6ac7df8b330343b37e3bee71e5c65267189
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	A2M EPS8 COL12A1 GPR20 DLC1 GUCY1A1 TMEM131L	1.39e-05	185	188	7	a8c02cec3c414f3a0da9f2d6d28ce563b0030705
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MAP4K3 CPNE5 TBC1D9 ARHGEF10L FAM171A1 TRPV6 GPR132	1.44e-05	186	188	7	d65fa6d8e8a195ea10cfde1499d096d6acf7a634
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6-Exc_L6_THEMIS_EGR3\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CPNE5 CHN2 TMEM244 GUCY1A1 TRPV6 DNAH6 EPHA3	1.44e-05	186	188	7	77b09af860183606a1775eba921e2071e4a7dd4e
ToppCell	droplet-Limb_Muscle-nan-21m-Mesenchymal-smooth_muscle_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR20 CHN1 BCR NKD1 GUCY1A1 PDE5A STK38L	1.50e-05	187	188	7	accb8a78b885703a27d4b560f0053f03d82ff3af
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	GPR20 SPEG ZFPM2 DLC1 NKD1 TMEM131L PDE5A	1.55e-05	188	188	7	b2d68a32314e9b099ed74d974079ad96359d1ae3
ToppCell	-Unknown-Endothelial-Myofibroblast\| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SNX4 USP24 CLOCK ZFPM2 SNX14 INTS9 EPHA3	1.55e-05	188	188	7	6468fa95ad0395395301115286f2d8c0df5d3882
ToppCell	-Unknown-Endothelial\| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SNX4 USP24 CLOCK ZFPM2 SNX14 INTS9 EPHA3	1.55e-05	188	188	7	7a81ac5c79c3eb26639b52d2b9fd5e7ef9798fd6
ToppCell	-Unknown\| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SNX4 USP24 CLOCK ZFPM2 SNX14 INTS9 EPHA3	1.55e-05	188	188	7	9cb718bfe1358c6fd842f096e228eb0abb9aefc6
ToppCell	COVID-19-Heart-Fib_1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	EPS8 COL12A1 RARRES1 ZFPM2 MRC2 KIAA1755 EPHA3	1.55e-05	188	188	7	fe361215f4ba841aa5e1e581fb56f2f4d3ccd201
ToppCell	facs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l39\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GPR20 SPEG CHN1 BCR GUCY1A1 PDE5A GPR176	1.55e-05	188	188	7	a5e7a363fbd5ae4d9312cf6f9941413d6a5c0b4d
ToppCell	droplet-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l32-30\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CADM4 GRIK3 CHN2 CADM2 TUBB3 TDRD6 ARHGEF26	1.55e-05	188	188	7	502045a39ffb1e92bd9499848368e8fa971edb88
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	USP34 NPEPPS USP24 ZNF407 SYNE2 TMEM131L MED13	1.55e-05	188	188	7	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	Mesenchymal-myofibroblast_cell\|World / Lineage, Cell type, age group and donor	FAT4 COL12A1 RARRES1 CHN1 ZFPM2 NKD1 SLC4A4	1.60e-05	189	188	7	44e37f88137bb249933eb615235b2cf2ae7f3925
Disease	Sarcomatoid Renal Cell Carcinoma	DNHD1 ACHE PIDD1 ASB15 RYR1 SYNE2 AKAP13	1.64e-05	128	184	7	C1266043
Disease	Chromophobe Renal Cell Carcinoma	DNHD1 ACHE PIDD1 ASB15 RYR1 SYNE2 AKAP13	1.64e-05	128	184	7	C1266042
Disease	Collecting Duct Carcinoma of the Kidney	DNHD1 ACHE PIDD1 ASB15 RYR1 SYNE2 AKAP13	1.64e-05	128	184	7	C1266044
Disease	Papillary Renal Cell Carcinoma	DNHD1 ACHE PIDD1 ASB15 RYR1 SYNE2 AKAP13	1.64e-05	128	184	7	C1306837
Disease	Renal Cell Carcinoma	DNHD1 ACHE PIDD1 ASB15 RYR1 SYNE2 AKAP13	1.64e-05	128	184	7	C0007134
Disease	Conventional (Clear Cell) Renal Cell Carcinoma	DNHD1 ACHE PIDD1 ASB15 RYR1 SYNE2 AKAP13	4.17e-05	148	184	7	C0279702
Disease	waist-hip ratio	IPO8 PHTF2 ZNF407 YTHDC2 ASB15 CLOCK WARS2 CADM2 FFAR4 ADAMTS10 DLC1 RAB43 SYNE2 DLG2 PDE5A MINDY4 RMC1 ARHGEF26 LRRC36 EPHA3	8.73e-05	1226	184	20	EFO_0004343
Disease	Corneal Opacity	WDR37 SLC4A4	2.30e-04	4	184	2	C0010038
Disease	Myopathy, Centronuclear, Autosomal Recessive	SPEG RYR1	2.30e-04	4	184	2	C0410204
Disease	MULTIPLE PTERYGIUM SYNDROME, LETHAL TYPE	NEB RYR1	5.71e-04	6	184	2	C1854678
Disease	Myeloid Leukemia, Chronic	PER1 BCR CRY2	7.74e-04	29	184	3	C0023473
Disease	lysosomal protective protein measurement	ZFPM2 TMEM131L	7.96e-04	7	184	2	EFO_0008215
Disease	Abnormality of the eye	WDR37 MED13	7.96e-04	7	184	2	C4316870
Disease	level of Sphingomyelin (d38:1) in blood serum	USP24 SYNE2 SLC4A4	8.56e-04	30	184	3	OBA_2045180
Disease	male homosexuality	FMR1NB TSHR	1.06e-03	8	184	2	EFO_0008486
Disease	chronic obstructive pulmonary disease	EFCAB5 CACNA1D DCHS2 SPEG FPR1 FRS2 TSEN54 PPP4R4 DLC1 MRC2 DLG2 DTHD1	1.35e-03	688	184	12	EFO_0000341
Disease	Colorectal Carcinoma	VPS18 ABCA12 PER1 NTNG1 HTR3C GRIK3 ARHGEF10L DLC1 BUB1B ATP11C EPHA3 EXOC4	1.59e-03	702	184	12	C0009402
Disease	Mastocytosis	MSH5 FTCD TRPV6	1.85e-03	39	184	3	EFO_0009001
Disease	Pancreatic Ductal Adenocarcinoma	ABCA12 EPHA3	2.05e-03	11	184	2	C1335302
Disease	Intellectual Disability	TSEN54 CHD3 ARMC9 WDR37 CERT1 FCSK SNX14 NRXN2 MED13	2.06e-03	447	184	9	C3714756
Disease	very low density lipoprotein cholesterol measurement, phospholipids:total lipids ratio	NPEPPS USP24 TSEN54 CERT1 FFAR4 PMPCA SYNE2	2.42e-03	291	184	7	EFO_0008317, EFO_0020946
Disease	C-C motif chemokine 17 measurement	ZFPM2 ACKR2	2.45e-03	12	184	2	EFO_0008045
Disease	Congenital myopathy (disorder)	NEB RYR1	2.45e-03	12	184	2	C0270960
Disease	resting heart rate	CACNA1D ACHE SPEG CPNE5 KIAA1755	2.48e-03	149	184	5	EFO_0004351
Disease	facial morphology measurement	DCHS2 FAT4 BCR WARS2 FAM171A1 TMEM244 COMMD10 DLG2 EPHA3	2.73e-03	466	184	9	EFO_0007841
Disease	very low density lipoprotein cholesterol measurement, cholesterol:total lipids ratio	USP24 TSEN54 CERT1 FFAR4 PMPCA SYNE2	2.77e-03	222	184	6	EFO_0008317, EFO_0020943
Disease	Thyroid Diseases	TSHR DIO1	2.88e-03	13	184	2	C0040128
Disease	heart rate	CACNA1D ACHE CPNE5 TMEM244 TBC1D1 KIAA1755	2.96e-03	225	184	6	EFO_0004326
Disease	triglycerides:total lipids ratio, very low density lipoprotein cholesterol measurement	NPEPPS USP24 TSEN54 CERT1 FFAR4 PMPCA	2.96e-03	225	184	6	EFO_0008317, EFO_0020947
Disease	Bipolar Disorder	SLC12A6 CACNA1D HDAC5 NTNG1 BCR CLOCK CRY2 DLG2 HTR3B	3.18e-03	477	184	9	C0005586
Disease	Liver Cirrhosis, Experimental	A2M COL12A1 RARRES1 ERAP1 ACHE FTCD BCR TBC1D9 NCOR2 PRODH2 DIO1 SLC4A4	3.53e-03	774	184	12	C0023893
Disease	spontaneous preterm birth	DLC1 GUCY1A1 DLG2 INTS9	3.73e-03	101	184	4	EFO_0006917
Disease	Schizophrenia	NRIP1 ACHE NTNG1 GRIK3 CLOCK PRODH2 HSPA12A NRXN2 PTPRZ1 DLG2 ADGRF4 HTR3B MSS51	3.75e-03	883	184	13	C0036341
Disease	Autosomal Recessive Centronuclear Myopathy	SPEG RYR1	3.85e-03	15	184	2	C3645536
Disease	urate measurement	USP34 SNX4 HDAC5 CHD3 NRXN2 DLG2 AKAP13 ILDR1 RORC MINDY4 QARS1 ARHGEF26 IQCE	4.20e-03	895	184	13	EFO_0004531
Disease	cardioembolic stroke	USP34 PHTF2 NCOR2 SYNE2 KIAA1755	4.35e-03	170	184	5	EFO_1001976
Disease	dual specificity mitogen-activated protein kinase kinase 2 measurement	LAMP1 PPP4R4	4.38e-03	16	184	2	EFO_0008112
Disease	coffee consumption, cups of coffee per day measurement	EFCAB5 POR	4.38e-03	16	184	2	EFO_0004330, EFO_0006782
Disease	Seasonal Affective Disorder	CLOCK CRY2	4.38e-03	16	184	2	C0085159
Disease	Cannabis use	IPO8 CADM2	4.38e-03	16	184	2	EFO_0007585
Disease	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma	ECT2L BCR JAK3	4.44e-03	53	184	3	C1961099
Disease	nose morphology measurement	DCHS2 C3orf38 NTNG1 ZNF407 ADAMTS10 DLC1 TBC1D1	4.74e-03	329	184	7	EFO_0007843
Disease	vitamin D measurement	NRIP1 SNX4 POR CADM2 RORC SLC4A4 EXOC4	5.31e-03	336	184	7	EFO_0004631
Disease	Mental Depression	A2M HDAC5 GRIK3 CLOCK CRY2 HTR3B	5.34e-03	254	184	6	C0011570
Disease	heart rate response to recovery post exercise	ACHE CPNE5 KIAA1755	5.45e-03	57	184	3	EFO_0009185
Disease	food allergy measurement, parental genotype effect measurement	DCHS2 IQCE	5.54e-03	18	184	2	EFO_0005939, EFO_0007016
Disease	obsessive-compulsive disorder, autism spectrum disorder	TUBB3 DLC1	6.17e-03	19	184	2	EFO_0003756, EFO_0004242

Protein segments in the cluster

Peptide	Gene	Start	Entry
VSQHLDYALQVTESI	ACKR2	286	O00590
DLLQHSEYITHEITV	BUB1B	846	O60566
VSDLAAEAVVLHYTD	ACHE	401	P22303
YVLLNLGDSVTTDHI	ACO1	666	P21399
VEQITLLISTLHGTY	ARHGEF10L	666	Q9HCE6
HYELFSTIDDIVLTI	CATSPER4	121	Q7RTX7
LVELSTALEHQEYIT	C1QBP	256	Q07021
TVDATSETHIYQVRL	CPSF2	596	Q9P2I0
ILASEETYLSHLEAL	BCR	506	P11274
TEIAASLLYHDNVIS	ABCA12	481	Q86UK0
ATTVYLDLFVHAILD	HTR3B	56	O95264
HTEALLVLCYSIVEN	ACRBP	321	Q8NEB7
LVVYHVAVTLSSLNS	GPR20	276	Q99678
LSSSVILTVYVHDVN	FAT4	976	Q6V0I7
YSEVANHILDTAAIS	ADGRF4	186	Q8IZF3
VVQSVVHLYELLSAL	AKAP13	2521	Q12802
HLTSYDIQLSIQESI	ASB15	11	Q8WXK1
VSLLETVFITYLLHV	HTR3C	321	Q8WXA8
SVYSVHALTLLSEVL	DOP1A	2031	Q5JWR5
VVSVVYEHSVTLESL	ECT2L	311	Q008S8
LEIILSSSILEIYNH	AASDH	611	Q4L235
SSSILEIYNHILQTV	AASDH	616	Q4L235
EVISSEHSYLLSLEI	ARHGEF26	446	Q96DR7
NLCTSILRLVHEDTY	DNHD1	456	Q96M86
SNTLHQELLSYVDVT	CCDC180	1001	Q9P1Z9
VANHDTAVLITRYDI	ADAMTS10	336	Q9H324
YVATVETLAQLHSLN	ACAD11	146	Q709F0
SRTEVSSNHVLIYLD	A2M	1406	P01023
AQHVRLLVDAEYTSL	PRODH2	306	Q9UF12
VTREDITSLLHTIYE	NKD1	151	Q969G9
ITSLLHTIYEVVDSS	NKD1	156	Q969G9
THLYIGTDLTQRIEA	RANBP17	16	Q9H2T7
VSLAEAQSLAEHYDI	RAB43	141	Q86YS6
IDLSTVDVILISNYH	INTS9	91	Q9NV88
HIFSVEDASTQVLLY	JAK3	86	P52333
YEEVHRLQTLLASSE	IQCE	256	Q6IPM2
LQTYSHEVSLIADSQ	PCDHGA11	751	Q9Y5H2
VETLADNAIIIYQTH	CERT1	481	Q9Y5P4
EQLYLELSQLTHSIT	MUC16	13876	Q8WXI7
HSETSLVAVVYLSRQ	MUC6	446	Q6W4X9
TLAQHISEVITQDYT	NCOR2	2131	Q9Y618
EGIYTLNLNELHETS	MAP4K3	581	Q8IVH8
IDSNHTEFIITLISV	OR10X1	206	Q8NGY0
QDITTYHTVFLLAIL	FAM171A1	296	Q5VUB5
FTVYITHLSIADISL	MAS1	66	P04201
SIRQYELVVHTDIDA	POR	241	P16435
TISIPYASQREAELH	GPR176	251	Q14439
VYSHQELVSSLQILV	MSS51	386	Q4VC12
YTLVVDEHAQLELVS	MAPK8IP1	381	Q9UQF2
AATALYSLVDEQLHV	KIAA1755	811	Q5JYT7
YSLVDEQLHVLVTAS	KIAA1755	816	Q5JYT7
VLQLLHSTSDVVRQY	ARMC9	376	Q7Z3E5
DYISGSLVIHNTDIE	ZFPM2	991	Q8WW38
YTLVVDEHTQLELVS	MAPK8IP2	511	Q13387
ELEYIVSVNTLVLGH	ARNTL2	461	Q8WYA1
VLETISFILEQAVYH	COMMD10	71	Q9Y6G5
VHYDLLIHANLTTLT	ERAP1	61	Q9NZ08
LELVVTDSIHQDYTT	FCAR	211	P24071
LTVSLAYSESHQIRV	FFAR4	241	Q5NUL3
LSNVDVYLDGHLITT	NADK	296	O95544
TLEELEHITSEYTLQ	PER1	201	O15534
LLHNYVTVDTDTLLS	IPO7	696	O95373
ILHESQRSLVVTNEY	LRRC36	676	Q1X8D7
HISELVLIYVVSFNI	OR5B3	191	Q8NH48
ELHTELEYSVLSQET	KATNAL2	446	Q8IYT4
VTLEVLSYHASAAEE	PDE5A	521	O76074
SDEYTLLTIHTVHVE	HHLA2	321	Q9UM44
VTVQHTERYVTLFAS	ILDR1	26	Q86SU0
LHYLVTISVDGILTT	NRXN2	396	Q9P2S2
ELGSDVHQDSIVLTY	NRIP1	6	P48552
ADLLSITEIHEQTYI	MRC2	271	Q9UBG0
LVIVINIYSSEHDNV	HSPA12A	596	O43301
QYVFIHDTLVEAILS	PTPRZ1	1981	P23471
FVTIADLSYQDVHLL	MROH8	156	Q9H579
YSALILHDDEVTVTE	RPLP1	11	P05386
SLVEIILVAVQHVDY	EXOC8	646	Q8IYI6
VLVADSNEDYLHSVV	MGAT4D	171	A6NG13
YELLIQISDSVHYTE	DCHS2	2416	Q6V1P9
IADFLVIYIEEAHAS	DIO1	146	P49895
LITASYVASILHATI	OR5T1	156	Q8NG75
ESIHDLVTDGLITLY	CHN2	121	P52757
YSIHLVEVDTQGLSL	FCSK	1056	Q8N0W3
EFVSLLLYDHTLVTE	EFCAB5	1346	A4FU69
LIVQHYTELTTAIRT	EXOC4	61	Q96A65
LFTLLSEEEYHLTEN	CKAP5	1271	Q14008
TTTEYVHSLLFLDEI	DNAH6	726	Q9C0G6
ILLDFVYTETVHVTV	KLHL12	86	Q53G59
HIIDFAYSAEVTLDL	KLHL26	116	Q53HC5
IYDIVNVLESLHLVS	E2F7	186	Q96AV8
VEVVTENSHTLYDLD	CRY2	141	Q49AN0
YAVTVQAVLHDLTSE	COL12A1	1541	Q99715
HVLLTSYELITIDQA	CHD3	856	Q12873
LLVAEEQVHTYVNTT	FRS2	186	Q8WU20
HYDENLLTSSVVIVF	GALNT7	201	Q86SF2
IYDEDVLAVEHVLTT	ATG9A	396	Q7Z3C6
AVHAILAYSQSAEEL	C3orf38	46	Q5JPI3
SAEYVLIVHDVPNTL	CADM2	306	Q8N3J6
LYTEDTHHQIATLTV	CADM4	106	Q8NFZ8
TIQSGLVSVELYEHL	DTHD1	461	Q6ZMT9
VTDLLAHTNYTFEID	EPHA3	396	P29320
HLLTAIQSDYLQASE	BTBD7	446	Q9P203
ILEDGSIYTTHDLIL	DSC1	71	Q08554
SYHTVSLQVSQDLLD	GBF1	1486	Q92538
VTVTLHDATIQAYLS	LAMP1	166	P11279
YSLEEVTHEEAVAIL	DLG2	251	Q15700
STYRVVSVLTVLHQD	IGHG1	181	P01857
VSSVSDISQYRVEHL	EPS8	56	Q12929
DISQYRVEHLTTFVL	EPS8	61	Q12929
TYDHTTILAVVAVVL	HBEGF	156	Q99075
TLDEIQTVHSEYHTL	HDAC5	736	Q9UQL6
ESIHDLVTDGLITLY	CHN1	111	P15882
SSLDIVLHDTYYVVA	MT-CO1	361	P00395
TDAALLYDAVHIVSV	GRIK3	321	Q13003
VAHLELATYELAATE	FMR1NB	21	Q8N0W7
SDVLGSLNHEYVLVD	SLC12A6	466	Q9UHW9
SLNHEYVLVDITTSF	SLC12A6	471	Q9UHW9
DDIILVSVSSERYLH	RYR1	166	P21817
ILSTLLSHTDFYEEI	NPEPPS	661	P55786
VLVFLNTLTISSEHY	CACNA1D	531	Q01668
TYVEVNDLTLTLSNH	HELB	311	Q8NG08
FVQVLETLSHDTLVT	CEBPZ	346	Q03701
LALTAVGEIIQHYDS	CPNE5	361	Q9HCH3
TNLLDFEVTALHTVY	FTCD	236	O95954
DITAQVVLELTHLYA	PIDD1	566	Q9HB75
LLHNYVTIDTDTLLS	IPO8	696	O15397
LTHLVNIDQDTYSVL	MSH5	216	O43196
NAELLSITEIHEQTY	MRC1	251	P22897
SITEIHEQTYLTGLT	MRC1	256	P22897
IIYVLATDHSRQEVS	GPR132	306	Q9UNW8
LSQHTVLEIICTEEY	NTNG1	196	Q9Y2I2
HFSVLQHEETTYIAI	NRK	1316	Q7Z2Y5
AELSLQAYHVTDTAL	FBXL16	271	Q8N461
QVHTEYSSLRSIVVA	HPD	216	P32754
IHTEPQLSAALEYVR	QARS1	81	P47897
ASELIGQLYDHITEA	PARS2	386	Q7L3T8
YDSVLYSIVDLHSIT	WARS2	66	Q9UGM6
DLTDLPTYEHIQTAL	PMPCA	496	Q10713
YSDELQSVISHLLRV	SNX4	226	O95219
EQLTAHSASELYVIA	PHTF2	526	Q8N3S3
FYIAETVLAIDSIHQ	STK38	191	Q15208
SSDYQVHLGELEITL	TPSG1	86	Q9NRR2
LDVYRLSSVVTQHDS	YARS1	131	P54577
QFYISETVLAIDAIH	STK38L	191	Q9Y2H1
YVQLIEDEAEISHLS	TDRD6	1321	O60522
FLTILQDESVSIHAY	PPP4R4	116	Q6NUP7
SIQEAYQLLLTDHTV	TSEN54	136	Q7Z6J9
LDHLSIVYVATDESE	TMEM131L	281	A2VDJ0
ISTHLQELTNIYEEL	SYNE2	2891	Q8WXH0
HTSAVRESYEELLQL	RNF165	231	Q6ZSG1
THTVTTISYLNLAVA	FPR1	56	P21462
YVVVTIDEHTAIILQ	SHOC1	911	Q5VXU9
EQILSDGTSVLHYDV	SI	1441	P14410
VYLLSEEHITLAQQS	MED13	186	Q9UHV7
PEAHSLYVNLILSES	MED13	1066	Q9UHV7
IHTLAQLISAYSLVD	SRP72	481	O76094
QFLSLEASTETLVHV	DLC1	96	Q96QB1
SITDQYHQSFLTVVL	PLA2R1	1151	Q13018
IIYVSESVTSLLEHL	CLOCK	131	O15516
YSLLEQHINIDTLTS	ATP11C	926	Q8NB49
VATHYLEIITQLIVE	SLC34A2	236	O95436
AVVALLLHYSIDEAE	TBC1D24	136	Q9ULP9
DYAISVTILHVAITS	TMEM244	91	Q5VVB8
HISSLLHSVEVEVSY	ZYG11B	586	Q9C0D3
SLYSSQTHEEILAEL	USPL1	961	Q5W0Q7
SVTDSLLLVHERYEQ	ZNF618	696	Q5T7W0
HFSEDEIALYTALVL	RORC	411	P51449
ETLTLHSLTCYEDLV	MINDY4	536	Q4G0A6
DEVLLTESSHVSFVY	SPEG	1521	Q15772
EAYEHVLSLLENVFT	SNX14	441	Q9Y5W7
TQAVLDQSDVYTHVL	RMC1	451	Q96DM3
VVLTATADHNLLLYE	TBL3	306	Q12788
HLLIALSSTEVLYVN	VPS18	111	Q9P253
YHVLQEELIDSSPLS	TBC1D1	1061	Q86TI0
EQELYHATAAVTSLL	TBC1D9	1046	Q6ZT07
TSELYEGQTALHIAV	TRPV6	151	Q9H1D0
ASQSLQSHTEYIIRV	PXK	26	Q7Z7A4
GESLLNDAVTVVLYH	SLC9A1	261	P19634
TLSIHQLVENTDETY	TUBB3	186	Q13509
ALVISLIFNISHYVE	TRAT1	21	Q6PIZ9
DQTLHRVATTASVIY	TEX50	131	A0A1B0GTY4
HDTLIETTDYAGLII	SNX5	76	Q9Y5X3
ETVHTAVRYTSIELV	TNPO3	471	Q9Y5L0
NLYDVETSELVHSLT	WDR37	306	Q9Y2I8
LILTENVSVDYRHSE	YTHDC2	491	Q9H6S0
QALEEHLTILSDAYA	USP24	571	Q9UPU5
YVAATVISIAHIDSL	SLC4A4	841	Q9Y6R1
VSSLHDIQSVPYLAD	STK32B	271	Q9NY57
VTIENHTPLVELSEY	ZNF597	121	Q96LX8
YSHTVLETADSQELL	ZNF407	2186	Q9C0G0
LEPSVHTEQTLYLAS	USP34	451	Q70CQ2
IDTVISSYNIETAHD	TEX15	396	Q9BXT5
SIDSNISLVHYIVAS	TMEM147	136	Q9BVK8
IDFDYTVLLHELSTQ	RARRES1	231	P49788
AEDNYTLVSHLIATE	MARS1	571	P56192
TLVSHLIATEYLNYE	MARS1	576	P56192
HLLIQVEIYANSSLT	TCTN2	136	Q96GX1
IYVSIDVTLQQLESH	TSHR	81	P16473
AAAHVLYETEVEVSL	GUCY1A1	221	Q02108
YLFLTELSQVQTHIS	KRT77	301	Q7Z794
YTLTETPLLHTAQEA	NEB	4191	P20929