Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
DomainCys-rich_flank_reg_C

ADGRA2 LRRC4C

1.01e-0390102IPR000483
DomainLRRCT

ADGRA2 LRRC4C

1.01e-0390102SM00082
DomainIg_sub

NCAN ADGRA2 LRRC4C

1.21e-03421103IPR003599
DomainIG

NCAN ADGRA2 LRRC4C

1.21e-03421103SM00409
DomainIG_LIKE

NCAN ADGRA2 LRRC4C

1.89e-03491103PS50835
DomainIg-like_dom

NCAN ADGRA2 LRRC4C

2.02e-03503103IPR007110
DomainLRR_8

ADGRA2 LRRC4C

3.57e-03171102PF13855
DomainLeu-rich_rpt_typical-subtyp

ADGRA2 LRRC4C

3.82e-03177102IPR003591
DomainLRR_TYP

ADGRA2 LRRC4C

3.82e-03177102SM00369
Domain-

NCAN ADGRA2 LRRC4C

4.43e-036631032.60.40.10
DomainIg_V-set

NCAN LRRC4C

4.80e-03199102IPR013106
DomainLRR

ADGRA2 LRRC4C

4.90e-03201102PS51450
DomainIg-like_fold

NCAN ADGRA2 LRRC4C

5.29e-03706103IPR013783
DomainLRR_1

ADGRA2 LRRC4C

5.79e-03219102PF00560
DomainLeu-rich_rpt

ADGRA2 LRRC4C

8.74e-03271102IPR001611
Domain-

ADGRA2 LRRC4C

1.21e-023211023.80.10.10
DomainL_dom-like

ADGRA2 LRRC4C

1.26e-02328102IPR032675
Pubmed

Expression pattern of LRR and Ig domain-containing protein (LRRIG protein) in the early mouse embryo.

ADGRA2 LRRC4C

4.15e-053410218848646
CoexpressionGSE21546_WT_VS_SAP1A_KO_AND_ELK1_KO_DP_THYMOCYTES_DN

ANKRD6 ADGRA2 LRRC4C

5.05e-05200103M7518
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_2-AT1_Progenitor|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CXCL17 NCAN

4.56e-04145102186b8bd8ac2d5c66cc29fdc2dd6751eddce3e8b8
ToppCellfacs-Pancreas-Exocrine-24m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANKRD6 ADGRA2

5.83e-04164102b895674ed2df87db8fbfb30b7e31620945588491
ToppCellwk_15-18-Epithelial-Airway_epithelial_progenitor-epi-prox-progenitor_intermediate_|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

CXCL17 ANKRD6

5.90e-04165102f6887c64af0f26e33316bc5587487e24d76ece2a
ToppCellE16.5-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CXCL17 ANKRD6

6.04e-0416710226cd8ee5e826e71eaf58d10a906543a6932fb3f9
ToppCellE16.5-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CXCL17 ANKRD6

6.04e-04167102fcd583b1efd0ac883379982ea8e6c54f2c0be268
ToppCellE16.5-Endothelial-Endothelial_lymphatic-Lymphatic_EC|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CXCL17 ANKRD6

6.04e-04167102f6bc63138b7239211fa5f27a8dc799b6e022c0f8
ToppCellE16.5-Endothelial-Endothelial_lymphatic|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CXCL17 ANKRD6

6.04e-04167102b93103a868fba63a8910bffb690a6242b9252833
ToppCellfacs-Heart-LV-18m-Mesenchymal-valve_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADGRA2 LRRC4C

6.48e-04173102d78397e65e997ddb995111a810f0e2a4f67d0765
ToppCelldroplet-Heart-HEART-1m-Endothelial-leukocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CXCL17 ANKRD6

6.48e-041731029dc7746a84f0e268a7c061e1bbcd5e31903034dc
ToppCellfacs-Heart-LV-18m-Mesenchymal-valve_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADGRA2 LRRC4C

6.48e-041731023c852ffe22f4a5b632463086b08c669310684e80
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CXCL17 ADGRA2

6.56e-041741023d4c05ea5719ca65e85d1f15198453034791087c
ToppCell(03)_Secretory-(4)_1wkpi|(03)_Secretory / shred by cell type and Timepoint

CXCL17 PER1

6.63e-0417510206b52f85baa31b55bb31477244892b6da79fe2c9
ToppCellfacs-Heart-LA-24m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CXCL17 ANKRD6

6.78e-041771021b153fbfe1323dc589de4af73a52149ea5ce6763
ToppCellfacs-Heart-LA-24m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CXCL17 ANKRD6

6.78e-0417710232fecefba1a55e1f418c9a055236fa11175c692d
ToppCelldroplet-Heart-nan-3m-Neuronal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HPS3 LRRC4C

7.01e-041801025b146a94708b3c3610542a4d0925f3f7a2b19185
ToppCelldroplet-Heart-nan-3m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HPS3 LRRC4C

7.01e-04180102da723df348d7b8449bb1124f23fe6fa706412adb
ToppCelldroplet-Heart-nan-3m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HPS3 LRRC4C

7.01e-0418010250758b1e7be2e43f83c10ab106900c067e61f5f7
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Macroglial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NCAN LRRC4C

7.09e-041811021037051eb82313c13346617b33f3c4c648181c4d
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NCAN LRRC4C

7.17e-04182102812ff2a50a510b18d865e89465dba1754a08ef61
ToppCelldroplet-Heart-4Chambers-18m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CXCL17 ADGRA2

7.25e-041831026c4a09c02e30e1f24dde39f8cb8c5b453826ee2e
ToppCellfacs-Thymus-Flowthrough-3m-Lymphocytic-DN_to_DP_transition_(most_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANKRD6 CLK3

7.41e-04185102dc59b8dc459a3c444c9634a0d438cbef54c40036
ToppCell15-Trachea-Epithelial-Secretory_progenitor|Trachea / Age, Tissue, Lineage and Cell class

CXCL17 LRRC4C

7.56e-04187102be9fce9e74b2f170a2067f1b31d802912a578329
ToppCell3'_v3-lymph-node_spleen-Hematopoietic_progenitors-Cycling_pre-Myeloid-2|lymph-node_spleen / Manually curated celltypes from each tissue

ZNF672 ADGRA2

7.56e-041871023c10b8501226c69d71bcd99dc1c064a3c2154f87
ToppCellILEUM-inflamed-(3)_MNP-(3)_moDC|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

PER1 LRRC4C

7.56e-041871020099def970fbc828756fbf853eca2ce77b8cd342
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Macroglial-Oligodendrocyte_progenitor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NCAN LRRC4C

7.65e-04188102d0e6fb4a3b3d79d3512b5500062ea285495ae526
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Macroglial-oligodendrocyte_precursor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NCAN LRRC4C

7.65e-04188102006db2c2c44971ca9241c582bc89f258c785f5ed
ToppCellfacs-Mammary_Gland-Mammary_Gland-18m|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PER1 HPS3

7.65e-041881025e13725136114e42d3b59647cf25e0f3c53abb54
ToppCellfacs-Thymus-Flowthrough-3m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANKRD6 CLK3

7.65e-0418810259b71462338a7efbacf46577cb07e9db3363afee
ToppCellfacs-Mammary_Gland-Mammary_Gland-18m-Epithelial|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PER1 HPS3

7.81e-0419010292456f6f7eced6e4c4371f495254a65d061c8d0b
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Macroglial-oligodendrocyte_precursor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NCAN LRRC4C

7.89e-04191102ece87127f85939e61b1048d968ed96f0e87c3a79
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Macroglial-Oligodendrocyte_progenitor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NCAN LRRC4C

7.89e-04191102478e8341ee03b05501e2233e02cef5f97492c95d
ToppCellIPF-Epithelial-Club|Epithelial / Disease state, Lineage and Cell class

CXCL17 ADGRA2

7.97e-04192102356e7a820b744a0ac87352a8d0e6e8d9fa9ed7d2
ToppCellAT2_cells-Donor_06|World / lung cells shred on cell class, cell subclass, sample id

CXCL17 LRRC4C

8.22e-04195102b0cea3f4e59635913d243612f2e8cf4c7b34e726
ToppCellCOPD-Epithelial-Club|Epithelial / Disease state, Lineage and Cell class

CXCL17 ADGRA2

8.30e-04196102af96fb94886e9395f3e2cd0a293af29229d017fe
ToppCellParenchymal-10x3prime_v2-Immune_Myeloid-Myeloid|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

PER1 ZNF672

8.64e-04200102cc8368665bc6bb7c4f39632ccff07ceaa98a7b65
ToppCellParenchymal-10x3prime_v2-Immune_Myeloid-Myeloid-Megakaryocyte|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

PER1 ZNF672

8.64e-042001020d76b006d8e8b32174e65e400acd0674354b962c
DrugDB04742

PER1 ADGRA2

3.63e-0521102CID005288990
DrugCefuroxime-d3

PER1 ADGRA2

5.61e-0526102CID000002658
Drugcm y

PER1 ADGRA2

6.06e-0527102CID016058609
DrugSulfamethazine sodium salt [1981-58-4]; Up 200; 13.4uM; PC3; HT_HG-U133A

ANKRD6 PER1 ADGRA2

6.89e-051931034322_UP
DrugRoxarsone [121-19-7]; Up 200; 15.2uM; MCF7; HT_HG-U133A

PER1 NCAN ADGRA2

7.10e-051951033511_UP
DrugTamoxifen citrate [54965-24-1]; Down 200; 7uM; HL60; HG-U133A

PER1 ADGRA2 ASH1L

7.10e-051951031366_DN
DrugSulfaguanidine [57-67-0]; Up 200; 18.6uM; MCF7; HT_HG-U133A

NCAN ADGRA2 ASH1L

7.43e-051981034839_UP
DrugAC1L1J28

PER1 ADGRA2

9.10e-0533102CID000004834
DrugAC1L1E3B

PER1 ADGRA2

1.63e-0444102CID000002622
DrugMerrem

PER1 ADGRA2

2.10e-0450102CID000060706
Drugazthreonam

PER1 ADGRA2

2.10e-0450102CID000002274
DrugCAS 64485-93-4

PER1 ADGRA2

2.10e-0450102CID000002631
DrugAC1L1E65

PER1 ADGRA2

2.28e-0452102CID000002656
Drugsodium sulbactam

PER1 ADGRA2

2.64e-0456102CID000005316
DrugCTK3D1047

PER1 ADGRA2

2.83e-0458102CID013293130
Diseaseaxial length measurement

ADGRA2 LRRC4C

2.39e-047792EFO_0005318
Diseasebipolar disorder

ANKRD6 NCAN

1.25e-0257792MONDO_0004985

Protein segments in the cluster

PeptideGeneStartEntry
HKHRHRHKHREHRSS

ASH1L

1481

Q9NR48
RHPNNVHHGRRAHKS

ADGRA2

1171

Q96PE1
RGPYRTRKHAHHCHK

CLK3

246

P49761
TRKHAHHCHKRRTRS

CLK3

251

P49761
HAHNHPKKRNRHRCS

ANKRD6

366

Q9Y2G4
RRHHCRSKAKRSRHH

PER1

831

O15534
RKQHHRQNHHAPTRT

LRRC4C

551

Q9HCJ2
KTRHQRHHRKPNKHS

CXCL17

86

Q6UXB2
RHHRKPNKHSRACQQ

CXCL17

91

Q6UXB2
VHHHPHKTNNRIRRT

HPS3

221

Q969F9
CTKPRRSHRMRRHHH

NCAN

1271

O14594
VHRRNHAGHKPHKCP

ZNF672

356

Q499Z4