Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcessactin filament fragmentation

CFL1 CFL2

1.58e-054342GO:0030043
GeneOntologyBiologicalProcesspositive regulation of protein-containing complex disassembly

IGF1R CFL1 CFL2

4.18e-0541343GO:0043243
GeneOntologyBiologicalProcessestablishment of Sertoli cell barrier

ARID4B ARID4A

7.34e-058342GO:0097368
GeneOntologyBiologicalProcessregulation of protein-containing complex disassembly

IGF1R CAMSAP2 CFL1 CFL2

8.98e-05144344GO:0043244
GeneOntologyCellularComponentnuclear matrix

CENPF PRPF40A CFL1 CFL2

7.65e-05140344GO:0016363
GeneOntologyCellularComponentnuclear periphery

CENPF PRPF40A CFL1 CFL2

1.66e-04171344GO:0034399
GeneOntologyCellularComponentSin3-type complex

ARID4B ARID4A

5.81e-0422342GO:0070822
GeneOntologyCellularComponentmicrotubule organizing center

CIR1 CENPF CAMSAP2 USO1 DYNC1H1 PPP1R12A DDX11

5.89e-04919347GO:0005815
DomainRBB1NT

ARID4B ARID4A

3.03e-062332IPR012603
DomainRBB1NT

ARID4B ARID4A

3.03e-062332PF08169
DomainADF/Cofilin

CFL1 CFL2

9.07e-063332IPR017904
DomainTudor-knot

ARID4B ARID4A

4.52e-056332IPR025995
DomainTudor-knot

ARID4B ARID4A

4.52e-056332PF11717
DomainADF

CFL1 CFL2

1.35e-0410332SM00102
DomainCofilin_ADF

CFL1 CFL2

1.35e-0410332PF00241
DomainADF-H

CFL1 CFL2

1.35e-0410332IPR002108
DomainADF_H

CFL1 CFL2

1.35e-0410332PS51263
Domain-

ARID4B ARID4A

3.13e-04153321.10.150.60
DomainARID

ARID4B ARID4A

3.13e-0415332PF01388
DomainBRIGHT

ARID4B ARID4A

3.13e-0415332SM00501
DomainARID_dom

ARID4B ARID4A

3.13e-0415332IPR001606
DomainARID

ARID4B ARID4A

3.13e-0415332PS51011
DomainBRCT

RFC1 TP53BP1

5.08e-0419332PF00533
DomainBRCT

RFC1 TP53BP1

6.84e-0422332SM00292
Domain-

RFC1 TP53BP1

7.48e-04233323.40.50.10190
Domain-

CFL1 CFL2

8.15e-04243323.40.20.10
DomainADF-H/Gelsolin-like_dom

CFL1 CFL2

8.15e-0424332IPR029006
DomainBRCT

RFC1 TP53BP1

9.58e-0426332PS50172
DomainTUDOR

ARID4B ARID4A

1.03e-0327332SM00333
DomainBRCT_dom

RFC1 TP53BP1

1.11e-0328332IPR001357
DomainTudor

ARID4B ARID4A

1.28e-0330332IPR002999
DomainChromodomain-like

ARID4B ARID4A

1.45e-0332332IPR016197
DomainCHROMO

ARID4B ARID4A

1.54e-0333332SM00298
DomainChromo/shadow_dom

ARID4B ARID4A

1.54e-0333332IPR000953
PathwayREACTOME_CELL_CYCLE

RFC1 CENPF USO1 DYNC1H1 PPP1R12A PSMA3 TP53BP1 HSP90AB1

3.19e-05694278M543
PathwayREACTOME_MITOTIC_G2_G2_M_PHASES

CENPF DYNC1H1 PPP1R12A PSMA3 HSP90AB1

3.42e-05200275M864
PathwayREACTOME_CELL_CYCLE_MITOTIC

RFC1 CENPF USO1 DYNC1H1 PPP1R12A PSMA3 HSP90AB1

6.75e-05561277M5336
PathwayREACTOME_CELL_CYCLE

RFC1 CENPF DYNC1H1 PPP1R12A PSMA3 TP53BP1 HSP90AB1

1.06e-04603277MM14635
PathwayREACTOME_MITOTIC_G2_G2_M_PHASES

DYNC1H1 PPP1R12A PSMA3 HSP90AB1

3.90e-04184274MM15145
PathwayREACTOME_SEMA3A_PAK_DEPENDENT_AXON_REPULSION

CFL1 HSP90AB1

4.17e-0416272M16498
Pubmed

Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.

EIF5B SRSF11 IGF1R RFC1 CAMSAP2 USO1 LMO7 PRPF40A CFL1 DYNC1H1 CUX1 PPP1R12A HSP90AB1

1.08e-101247351327684187
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

EIF5B SRSF11 CFAP210 CENPF FAM133A CAMSAP2 LMO7 CFL1 CFL2 CUX1 PPP1R12A HSP90AB1 DDX11

6.38e-101442351335575683
Pubmed

A comprehensive resource of interacting protein regions for refining human transcription factor networks.

EIF5B SRSF11 IGF1R ARID4B CAMSAP2 PPP1R12A TP53BP1

7.97e-1019135720195357
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

EIF5B SRSF11 RFC1 ARID4B ARID4A PRPF40A CFL1 CFL2 CUX1 TP53BP1 HSP90AB1

1.43e-09954351136373674
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

EIF5B RFC1 ARID4B ARID4A LMO7 USP16 PRPF40A PSMA3 TP53BP1 HSP90AB1

3.12e-09774351015302935
Pubmed

Tumor suppressor BAP1 nuclear import is governed by transportin-1.

EIF5B RFC1 USO1 LMO7 PRPF40A CFL1 CFL2 DYNC1H1 PPP1R12A PSMA3 HSP90AB1

9.83e-091149351135446349
Pubmed

PINK1 Content in Mitochondria is Regulated by ER-Associated Degradation.

EIF5B LMO7 PRPF40A CFL1 DYNC1H1 CUX1 PPP1R12A HSP90AB1

2.01e-0847735831300519
Pubmed

A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

EIF5B RFC1 CENPF LMO7 CFL1 PSMA3 TP53BP1 HSP90AB1

3.03e-0850335816964243
Pubmed

Nuclear actin interactome analysis links actin to KAT14 histone acetyl transferase and mRNA splicing.

SRSF11 CENPF LMO7 PRPF40A CFL1 CFL2 DYNC1H1 TP53BP1

3.17e-0850635830890647
Pubmed

ADF/cofilin-mediated actin retrograde flow directs neurite formation in the developing brain.

CFL1 CFL2 CUX1

1.11e-071035323259946
Pubmed

Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.

SRSF11 RFC1 POLR1A CBLB LMO7 PRPF40A CFL1 CUX1 PPP1R12A

1.16e-0784735935850772
Pubmed

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.

EIF5B ARID4B ARID4A USO1 DYNC1H1 CUX1 PPP1R12A TP53BP1 HSP90AB1

1.28e-0785735925609649
Pubmed

Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization.

IGF1R LMO7 PRPF40A DYNC1H1 PPP1R12A HSP90AB1

1.99e-0725535615324660
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

EIF5B RFC1 CAMSAP2 USP16 PRPF40A CFL1 PPP1R12A TP53BP1 HSP90AB1

2.64e-0793435933916271
Pubmed

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.

EIF5B RFC1 CENPF LMO7 USP16 CFL1 CFL2 DYNC1H1 PPP1R12A HSP90AB1

2.95e-071257351036526897
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

EIF5B SRSF11 POLR1A CENPF LMO7 PRPF40A CFL1 DYNC1H1 HSP90AB1

5.69e-07102435924711643
Pubmed

A bead-based approach for large-scale identification of in vitro kinase substrates.

EIF5B SRSF11 PRPF40A PSMA3 HSP90AB1

6.16e-0716335522113938
Pubmed

HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.

SRSF11 RFC1 FAM133A USO1 LMO7 PRPF40A CFL1 DYNC1H1 PSMA3 HSP90AB1

6.54e-071371351036244648
Pubmed

Functional specialization of beta-arrestin interactions revealed by proteomic analysis.

POLR1A CENPF CFL1 DYNC1H1 PPP1R12A HSP90AB1

7.11e-0731735617620599
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

EIF5B RFC1 POLR1A CENPF USO1 PRPF40A CFL1 DYNC1H1 PSMA3 HSP90AB1

9.29e-071425351030948266
Pubmed

Malignant progressive tumor cell clone exhibits significant up-regulation of cofilin-2 and 27-kDa modified form of cofilin-1 compared to regressive clone.

CFL1 CFL2

9.84e-07235224023293
Pubmed

Differential expression of up-regulated cofilin-1 and down-regulated cofilin-2 characteristic of pancreatic cancer tissues.

CFL1 CFL2

9.84e-07235221894436
Pubmed

Mapping of human non-muscle type cofilin (CFL1) to chromosome 11q13 and muscle-type cofilin (CFL2) to chromosome 14.

CFL1 CFL2

9.84e-0723528800436
Pubmed

Cofilin hyperactivation in HIV infection and targeting the cofilin pathway using an anti-α4β7 integrin antibody.

CFL1 CFL2

9.84e-07235230662943
Pubmed

Identification of chromatin remodeling genes Arid4a and Arid4b as leukemia suppressor genes.

ARID4B ARID4A

9.84e-07235218728284
Pubmed

The ADF/cofilin proteins: stimulus-responsive modulators of actin dynamics.

CFL1 CFL2

9.84e-0723528589446
Pubmed

The ADF/cofilin family: actin-remodeling proteins.

CFL1 CFL2

9.84e-07235212049672
Pubmed

Characterization of a novel cofilin isoform that is predominantly expressed in mammalian skeletal muscle.

CFL1 CFL2

9.84e-0723528195165
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

LMO7 PRPF40A CFL1 DYNC1H1 CUX1 PPP1R12A TP53BP1

1.08e-0654935738280479
Pubmed

Faciogenital Dysplasia 5 supports cancer stem cell traits in basal-like breast cancer by enhancing EGFR stability.

IGF1R LMO7 DYNC1H1 PPP1R12A HSP90AB1

1.35e-0619135533762435
Pubmed

Folate receptor α increases chemotherapy resistance through stabilizing MDM2 in cooperation with PHB2 that is overcome by MORAb-202 in gastric cancer.

SRSF11 FAM133A PRPF40A CFL1 HSP90AB1

1.95e-0620635534185411
Pubmed

Molecular Characterization of the Oncogene BTF3 and Its Targets in Colorectal Cancer.

RFC1 LMO7 CFL1 DYNC1H1 CUX1 PPP1R12A HSP90AB1

2.57e-0662635733644029
Pubmed

Dephosphorylation of serine 3 regulates nuclear translocation of cofilin.

CFL1 CFL2

2.95e-0633528824278
Pubmed

Downregulation of ARID4A and ARID4B promote tumor progression and directly regulated by microRNA-30d in patient with prostate cancer.

ARID4B ARID4A

2.95e-06335229797600
Pubmed

Nuclear IGF1R interacts with NuMA and regulates 53BP1‑dependent DNA double‑strand break repair in colorectal cancer.

IGF1R TP53BP1

2.95e-06335234165167
Pubmed

The Warsaw breakage syndrome-related protein DDX11 is required for ribosomal RNA synthesis and embryonic development.

POLR1A DDX11

2.95e-06335226089203
Pubmed

TIRF microscopy analysis of human Cof1, Cof2, and ADF effects on actin filament severing and turnover.

CFL1 CFL2

2.95e-06335226996939
Pubmed

Biophysics of actin filament severing by cofilin.

CFL1 CFL2

2.95e-06335223395798
Pubmed

How to engage Cofilin.

CFL1 CFL2

2.95e-06335218808680
Pubmed

The three mouse actin-depolymerizing factor/cofilins evolved to fulfill cell-type-specific requirements for actin dynamics.

CFL1 CFL2

2.95e-06335211809832
Pubmed

HIV-1 Nef interferes with host cell motility by deregulation of Cofilin.

CFL1 CFL2

2.95e-06335219683683
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

EIF5B RFC1 POLR1A CENPF PRPF40A DYNC1H1 TP53BP1

3.39e-0665335722586326
Pubmed

SMYD3 Impedes Small Cell Lung Cancer Sensitivity to Alkylation Damage through RNF113A Methylation-Phosphorylation Cross-talk.

CIR1 EIF5B SRSF11 RFC1 PRPF40A CFL1 HSP90AB1

3.46e-0665535735819319
Pubmed

TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.

EIF5B POLR1A LMO7 PRPF40A CFL1 DYNC1H1 PPP1R12A HSP90AB1

3.65e-0694935836574265
Pubmed

Large-scale mapping of human protein-protein interactions by mass spectrometry.

SRSF11 IGF1R USO1 PRPF40A BARHL1 CFL1 DYNC1H1 PPP1R12A PSMA3

3.67e-06128435917353931
Pubmed

Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.

CIR1 EIF5B SRSF11 RFC1 CFL1 DYNC1H1 PPP1R12A TP53BP1 HSP90AB1

3.99e-06129735933545068
Pubmed

Charting the landscape of tandem BRCT domain-mediated protein interactions.

EIF5B PRPF40A CFL1 DYNC1H1 CUX1 PPP1R12A TP53BP1

4.01e-0667035722990118
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

CENPF CAMSAP2 CFL1 DYNC1H1 CUX1 PPP1R12A TP53BP1 HSP90AB1

4.07e-0696335828671696
Pubmed

BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.

EIF5B SRSF11 RFC1 POLR1A USP16 PRPF40A CFL1 DYNC1H1 HSP90AB1

4.54e-06131835930463901
Pubmed

SLFN11 promotes CDT1 degradation by CUL4 in response to replicative DNA damage, while its absence leads to synthetic lethality with ATR/CHK1 inhibitors.

EIF5B RFC1 POLR1A CENPF TP53BP1

5.02e-0625035533536335
Pubmed

ATG5 is required for B cell polarization and presentation of particulate antigens.

CIR1 IKZF3 POLR1A FAM133A PPP1R12A PSMA3 HSP90AB1

5.40e-0670135730196744
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

EIF5B RFC1 POLR1A USP16 CFL1 DYNC1H1 PSMA3 TP53BP1 HSP90AB1

5.62e-06135335929467282
Pubmed

ARID4A and ARID4B regulate male fertility, a functional link to the AR and RB pathways.

ARID4B ARID4A

5.90e-06435223487765
Pubmed

Cofilin weakly interacts with 14-3-3 and therefore can only indirectly participate in regulation of cell motility by small heat shock protein HspB6 (Hsp20).

CFL1 CFL2

5.90e-06435222450169
Pubmed

Deficiency of Rbbp1/Arid4a and Rbbp1l1/Arid4b alters epigenetic modifications and suppresses an imprinting defect in the PWS/AS domain.

ARID4B ARID4A

5.90e-06435217043311
Pubmed

Expression of cofilin isoforms during development of mouse striated muscles.

CFL1 CFL2

5.90e-06435210813634
Pubmed

Control of growth cone motility and morphology by LIM kinase and Slingshot via phosphorylation and dephosphorylation of cofilin.

CFL1 CFL2

5.90e-06435212684437
Pubmed

ADF/Cofilin-Mediated Actin Turnover Promotes Axon Regeneration in the Adult CNS.

CFL1 CFL2

5.90e-06435231400829
Pubmed

Golgin tethers define subpopulations of COPI vesicles.

USO1 CUX1

5.90e-06435215718469
Pubmed

Matrix-screening reveals a vast potential for direct protein-protein interactions among RNA binding proteins.

EIF5B SRSF11 USO1 PRPF40A CFL1 HSP90AB1 DDX11

6.60e-0672335734133714
Pubmed

Interactome and Ubiquitinome Analyses Identify Functional Targets of Herpes Simplex Virus 1 Infected Cell Protein 0.

LMO7 CFL1 PPP1R12A PSMA3

7.40e-0612435435516420
Pubmed

Human transcription factor protein interaction networks.

IKZF3 RFC1 ARID4B ARID4A PRPF40A DYNC1H1 CUX1 PSMA3 TP53BP1

8.73e-06142935935140242
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

CAMSAP2 USO1 LMO7 PRPF40A CFL1 CFL2 DYNC1H1 PPP1R12A HSP90AB1

8.83e-06143135937142655
Pubmed

The ferroxidase ceruloplasmin influences Reelin processing, cofilin phosphorylation and neuronal organization in the developing brain.

CFL1 CUX1

9.82e-06535230077770
Pubmed

Landscape of the SOX2 protein-protein interactome.

RFC1 CFL1 PPP1R12A HSP90AB1

1.07e-0513635421280222
Pubmed

Wnt regulation: exploring Axin-Disheveled interactions and defining mechanisms by which the SCF E3 ubiquitin ligase is recruited to the destruction complex.

EIF5B RFC1 PRPF40A CFL1 DYNC1H1 PPP1R12A HSP90AB1

1.37e-0580935732129710
Pubmed

Next-generation sequencing to generate interactome datasets.

SRSF11 ZKSCAN7 IKZF3 CBLB PRPF40A CFL1 CFL2 PSMA3

1.45e-05114735821516116
Pubmed

Cofilin phosphorylation by LIM-kinase 1 and its role in Rac-mediated actin reorganization.

CFL1 CFL2

1.47e-0563529655398
Pubmed

Opposing roles for 53BP1 during homologous recombination.

CENPF TP53BP1

1.47e-05635223969417
Pubmed

Systematic identification of factors for provirus silencing in embryonic stem cells.

RFC1 USO1 PPP1R12A TP53BP1

1.70e-0515335426365490
Pubmed

Two-Dimensional Fractionation Method for Proteome-Wide Cross-Linking Mass Spectrometry Analysis.

POLR1A PRPF40A CFL1 CFL2 DYNC1H1 PSMA3 HSP90AB1

1.84e-0584735735235311
Pubmed

Proteome-wide analysis of USP14 substrates revealed its role in hepatosteatosis via stabilization of FASN.

EIF5B CFL1 CFL2 DYNC1H1 PSMA3

2.03e-0533435530425250
Pubmed

Homozygous ARHGEF2 mutation causes intellectual disability and midbrain-hindbrain malformation.

BARHL1 CUX1

2.06e-05735228453519
Pubmed

LukS-PV inhibits hepatocellular carcinoma cells migration by downregulating HDAC6 expression.

EIF5B LMO7 CFL1 DYNC1H1 PPP1R12A HSP90AB1

2.26e-0558035635676659
Pubmed

Telencephalic embryonic subtractive sequences: a unique collection of neurodevelopmental genes.

IGF1R ARID4B CENPF TP53BP1

2.28e-0516535416107646
Pubmed

Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.

SRSF11 USO1 LMO7 PRPF40A DYNC1H1 HSP90AB1

2.30e-0558235620467437
Pubmed

The Tumor Suppressor CIC Directly Regulates MAPK Pathway Genes via Histone Deacetylation.

RFC1 ARID4B ARID4A CUX1 TP53BP1 HSP90AB1

2.32e-0558335629844126
Pubmed

DNA damage response in microcephaly development of MCPH1 mouse model.

CUX1 TP53BP1

2.74e-05835223683352
Pubmed

Identification and characterization of three new components of the mSin3A corepressor complex.

ARID4B ARID4A

2.74e-05835212724404
Pubmed

Filamin-A regulates actin-dependent clustering of HIV receptors.

CFL1 CFL2

2.74e-05835217572668
Pubmed

N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.

SRSF11 USO1 LMO7 DYNC1H1 TP53BP1

2.91e-0536035533111431
Pubmed

ALS/FTD-causing mutation in cyclin F causes the dysregulation of SFPQ.

LMO7 PRPF40A CFL1 PPP1R12A PSMA3 HSP90AB1

3.39e-0562435633729478
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

SRSF11 RFC1 ARID4B ARID4A CENPF LMO7 PRPF40A CUX1

3.45e-05129435830804502
Pubmed

HIV envelope-CXCR4 signaling activates cofilin to overcome cortical actin restriction in resting CD4 T cells.

CFL1 CFL2

3.53e-05935218775311
Pubmed

Spatiotemporal Gradient of Cortical Neuron Death Contributes to Microcephaly in Knock-In Mouse Model of Ligase 4 Syndrome.

CUX1 TP53BP1

3.53e-05935231541646
Pubmed

Family with sequence similarity 60A (FAM60A) protein is a cell cycle-fluctuating regulator of the SIN3-HDAC1 histone deacetylase complex.

ARID4B ARID4A DYNC1H1

3.73e-056435322865885
Pubmed

Comprehensive proteomic analysis of interphase and mitotic 14-3-3-binding proteins.

RFC1 LMO7 CFL1 DYNC1H1

3.96e-0519035415161933
Pubmed

Hsp90 cochaperone Aha1 downregulation rescues misfolding of CFTR in cystic fibrosis.

LMO7 CFL1 CFL2 HSP90AB1

4.38e-0519535417110338
Pubmed

Nomenclature of the ARID family of DNA-binding proteins.

ARID4B ARID4A

4.40e-051035215922553
Pubmed

BAG-2 acts as an inhibitor of the chaperone-associated ubiquitin ligase CHIP.

PSMA3 HSP90AB1

4.40e-051035216207813
Pubmed

ZZW-115-dependent inhibition of NUPR1 nuclear translocation sensitizes cancer cells to genotoxic agents.

EIF5B SRSF11 POLR1A PRPF40A CFL2 PPP1R12A

4.64e-0566035632780723
Pubmed

The ubiquitin-dependent ATPase p97 removes cytotoxic trapped PARP1 from chromatin.

POLR1A USO1 LMO7 PRPF40A TP53BP1

4.80e-0540035535013556
Pubmed

MYC multimers shield stalled replication forks from RNA polymerase.

SRSF11 RFC1 CENPF PRPF40A CFL1 TP53BP1 HSP90AB1

4.93e-0598935736424410
Pubmed

Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.

EIF5B RFC1 USO1 PRPF40A CFL1 PSMA3 TP53BP1 HSP90AB1

5.09e-05136735832687490
Pubmed

Targeting SKA3 suppresses the proliferation and chemoresistance of laryngeal squamous cell carcinoma via impairing PLK1-AKT axis-mediated glycolysis.

RFC1 PRPF40A TP53BP1

5.31e-057235333106477
Pubmed

Androgen Receptor Coactivator ARID4B Is Required for the Function of Sertoli Cells in Spermatogenesis.

ARID4B ARID4A

5.38e-051135226258622
Pubmed

N-terminal Slit2 inhibits HIV-1 replication by regulating the actin cytoskeleton.

CFL1 CFL2

5.38e-051135223294842
Pubmed

Suppression of DNA Double-Strand Break Formation by DNA Polymerase β in Active DNA Demethylation Is Required for Development of Hippocampal Pyramidal Neurons.

CUX1 TP53BP1

5.38e-051135233087478
Pubmed

Loss of TRIM31 promotes breast cancer progression through regulating K48- and K63-linked ubiquitination of p53.

EIF5B USO1 PRPF40A CFL1 HSP90AB1

6.11e-0542135534650049
Pubmed

CAMSAP1 breaks the homeostatic microtubule network to instruct neuronal polarity.

CAMSAP2 CUX1

6.45e-051235232839317
InteractionENO1 interactions

EIF5B IKZF3 POLR1A CENPF CFL1 DYNC1H1 PPP1R12A PSMA3 TP53BP1 HSP90AB1

1.09e-077013310int:ENO1
InteractionSMC5 interactions

EIF5B SRSF11 RFC1 ARID4B ARID4A PRPF40A CFL1 CFL2 CUX1 TP53BP1 HSP90AB1

3.00e-0710003311int:SMC5
InteractionBAP1 interactions

EIF5B IGF1R RFC1 USO1 LMO7 PRPF40A CFL1 CFL2 DYNC1H1 PPP1R12A PSMA3 HSP90AB1

5.51e-0713143312int:BAP1
InteractionCAP2 interactions

PRPF40A CFL1 CFL2 HSP90AB1

4.00e-0666334int:CAP2
InteractionDBN1 interactions

EIF5B FAM133A LMO7 CFL1 CFL2 PPP1R12A HSP90AB1

4.14e-06417337int:DBN1
InteractionARRB2 interactions

IGF1R POLR1A CENPF CFL1 DYNC1H1 PPP1R12A HSP90AB1

7.23e-06454337int:ARRB2
InteractionYWHAQ interactions

IGF1R RFC1 CAMSAP2 USO1 LMO7 CFL1 DYNC1H1 PPP1R12A PSMA3 HSP90AB1

7.60e-0611183310int:YWHAQ
InteractionECT2 interactions

CIR1 EIF5B LMO7 CFL1 CFL2 DYNC1H1 CUX1 PPP1R12A HSP90AB1

8.84e-06887339int:ECT2
InteractionPPIA interactions

CACNA1D IKZF3 RFC1 CENPF USP16 CFL1 CUX1 PPP1R12A TP53BP1

8.92e-06888339int:PPIA
InteractionOBSL1 interactions

EIF5B SRSF11 RFC1 POLR1A CBLB CENPF PRPF40A DYNC1H1 HSP90AB1

1.01e-05902339int:OBSL1
InteractionPINK1 interactions

EIF5B LMO7 PRPF40A CFL1 DYNC1H1 CUX1 PPP1R12A HSP90AB1

1.05e-05679338int:PINK1
InteractionCEBPB interactions

EIF5B SRSF11 RFC1 USO1 PRPF40A CFL1 DYNC1H1 CUX1 PSMA3 TP53BP1 HSP90AB1

1.08e-0514433311int:CEBPB
InteractionCIT interactions

EIF5B POLR1A CENPF LMO7 PRPF40A CFL1 CFL2 DYNC1H1 CUX1 PPP1R12A HSP90AB1

1.13e-0514503311int:CIT
InteractionSPOP interactions

EIF5B USO1 TSHZ2 PRPF40A DYNC1H1 PPP1R12A TP53BP1

1.20e-05491337int:SPOP
InteractionACTC1 interactions

SRSF11 CENPF LMO7 PRPF40A CFL1 CFL2 DYNC1H1 TP53BP1

1.23e-05694338int:ACTC1
InteractionMAD2L2 interactions

IKZF3 RFC1 POLR1A CFL2 DYNC1H1 TP53BP1

1.29e-05325336int:MAD2L2
InteractionPRC1 interactions

EIF5B CENPF LMO7 PRPF40A CFL1 CFL2 DYNC1H1 PPP1R12A HSP90AB1

1.85e-05973339int:PRC1
InteractionNAA40 interactions

EIF5B RFC1 CAMSAP2 USP16 PRPF40A CFL1 PPP1R12A TP53BP1 HSP90AB1

1.93e-05978339int:NAA40
InteractionFGD5 interactions

IGF1R LMO7 DYNC1H1 PPP1R12A HSP90AB1

2.05e-05207335int:FGD5
InteractionSMARCC2 interactions

ARID4B PRPF40A PPP1R12A PSMA3 TP53BP1 HSP90AB1

2.06e-05353336int:SMARCC2
InteractionNFIC interactions

ZKSCAN7 ARID4B CAMSAP2 CUX1 TP53BP1

2.19e-05210335int:NFIC
InteractionCRK interactions

ZKSCAN7 IKZF3 IGF1R CBLB PPP1R12A HSP90AB1

2.68e-05370336int:CRK
InteractionFOXK2 interactions

EIF5B ARID4B ARID4A CUX1 TP53BP1

3.05e-05225335int:FOXK2
InteractionDDX39B interactions

LMO7 PRPF40A CFL1 DYNC1H1 PPP1R12A TP53BP1 HSP90AB1

3.14e-05570337int:DDX39B
InteractionPARP1 interactions

IKZF3 RFC1 POLR1A ARID4B USO1 LMO7 PRPF40A CUX1 TP53BP1 HSP90AB1

3.15e-0513163310int:PARP1
InteractionFOLR1 interactions

SRSF11 FAM133A PRPF40A CFL1 HSP90AB1

3.18e-05227335int:FOLR1
InteractionRUVBL1 interactions

SRSF11 IKZF3 IGF1R POLR1A PPP1R12A PSMA3 TP53BP1

3.32e-05575337int:RUVBL1
InteractionBIRC3 interactions

EIF5B RFC1 POLR1A CENPF USO1 PRPF40A CFL1 DYNC1H1 PSMA3 HSP90AB1

3.54e-0513343310int:BIRC3
InteractionDOT1L interactions

SRSF11 RFC1 POLR1A LMO7 PRPF40A CFL1 CUX1 PPP1R12A

3.64e-05807338int:DOT1L
InteractionCDK1 interactions

IGF1R ARID4A CENPF USP16 CUX1 PPP1R12A TP53BP1

3.92e-05590337int:CDK1
InteractionHDAC1 interactions

IKZF3 RFC1 ARID4B ARID4A CENPF USO1 LMO7 CUX1 HSP90AB1

5.16e-051108339int:HDAC1
InteractionMYO19 interactions

LMO7 CFL1 CFL2 PPP1R12A HSP90AB1

5.24e-05252335int:MYO19
InteractionNR2C2 interactions

EIF5B SRSF11 RFC1 POLR1A USP16 PRPF40A CFL1 DYNC1H1 TP53BP1 HSP90AB1

5.45e-0514033310int:NR2C2
InteractionHDLBP interactions

SRSF11 RFC1 USO1 LMO7 USP16 PRPF40A CFL1 DYNC1H1

5.48e-05855338int:HDLBP
InteractionERLEC1 interactions

IGF1R LMO7 PRPF40A PPP1R12A

5.51e-05128334int:ERLEC1
InteractionHDAC2 interactions

CIR1 IKZF3 ARID4B ARID4A DYNC1H1 PPP1R12A PSMA3 HSP90AB1

5.95e-05865338int:HDAC2
InteractionCUL1 interactions

RFC1 POLR1A PRPF40A CFL1 CUX1 PPP1R12A PSMA3 HSP90AB1

6.50e-05876338int:CUL1
InteractionEED interactions

EIF5B IGF1R ARID4B CBLB USO1 PRPF40A CFL1 DYNC1H1 TP53BP1 HSP90AB1

6.99e-0514453310int:EED
InteractionFLNA interactions

SRSF11 CFL1 CFL2 DYNC1H1 PPP1R12A TP53BP1 HSP90AB1

7.09e-05648337int:FLNA
InteractionWIF1 interactions

RFC1 USO1 PRPF40A PPP1R12A

8.94e-05145334int:WIF1
InteractionGAPDH interactions

IKZF3 RFC1 PRPF40A CFL1 PPP1R12A PSMA3 HSP90AB1

1.01e-04686337int:GAPDH
InteractionCDK4 interactions

IKZF3 IGF1R RFC1 ARID4A HSP90AB1

1.05e-04292335int:CDK4
InteractionRNF113A interactions

CIR1 EIF5B SRSF11 RFC1 PRPF40A CFL1 HSP90AB1

1.07e-04692337int:RNF113A
InteractionCSNK2A1 interactions

EIF5B SRSF11 POLR1A ARID4B FAM133A PRPF40A PSMA3 HSP90AB1

1.20e-04956338int:CSNK2A1
InteractionYWHAG interactions

SRSF11 IGF1R CAMSAP2 LMO7 PRPF40A CFL1 DYNC1H1 PPP1R12A HSP90AB1

1.29e-041248339int:YWHAG
InteractionBRCA1 interactions

EIF5B RFC1 POLR1A CENPF FAM133A USO1 DYNC1H1 TP53BP1 HSP90AB1

1.30e-041249339int:BRCA1
InteractionISG15 interactions

LMO7 CFL1 DYNC1H1 PPP1R12A PSMA3 HSP90AB1

1.33e-04494336int:ISG15
InteractionCSNK2A2 interactions

POLR1A ARID4B FAM133A CAMSAP2 PRPF40A TP53BP1 HSP90AB1

1.35e-04718337int:CSNK2A2
InteractionLRRK2 interactions

CBLB CFL1 DYNC1H1 PPP1R12A PSMA3 HSP90AB1

1.36e-04496336int:LRRK2
InteractionPOLR1C interactions

IKZF3 POLR1A CFL1 TP53BP1 HSP90AB1

1.41e-04311335int:POLR1C
InteractionHERC2 interactions

EIF5B SRSF11 USP16 PRPF40A CUX1 TP53BP1

1.47e-04503336int:HERC2
InteractionMAPRE1 interactions

EIF5B CAMSAP2 LMO7 DYNC1H1 PPP1R12A HSP90AB1

1.65e-04514336int:MAPRE1
InteractionCHAF1A interactions

RFC1 ARID4B USO1 PPP1R12A TP53BP1

1.66e-04322335int:CHAF1A
InteractionHDAC4 interactions

EIF5B IKZF3 ARID4B CAMSAP2 LMO7 TP53BP1 HSP90AB1

1.68e-04744337int:HDAC4
InteractionSIRT7 interactions

EIF5B RFC1 POLR1A CENPF PRPF40A DYNC1H1 TP53BP1

1.68e-04744337int:SIRT7
InteractionCTNNB1 interactions

IGF1R USO1 LMO7 CFL1 DYNC1H1 CUX1 PPP1R12A HSP90AB1

1.74e-041009338int:CTNNB1
InteractionTES interactions

IGF1R LMO7 CFL1 DYNC1H1 HSP90AB1

1.91e-04332335int:TES
InteractionPHLPP1 interactions

EIF5B SRSF11 CENPF LMO7 DYNC1H1

1.94e-04333335int:PHLPP1
InteractionKIF23 interactions

EIF5B RFC1 PRPF40A CFL1 CFL2 DYNC1H1 PPP1R12A HSP90AB1

2.02e-041031338int:KIF23
InteractionSAP130 interactions

ARID4B ARID4A CFL2 TP53BP1

2.10e-04181334int:SAP130
InteractionFBXO22 interactions

IGF1R POLR1A CENPF LMO7 PPP1R12A TP53BP1

2.15e-04540336int:FBXO22
InteractionB3GNT2 interactions

EIF5B IGF1R PRPF40A CFL1 PSMA3 HSP90AB1

2.20e-04542336int:B3GNT2
InteractionCAPZB interactions

POLR1A LMO7 CFL1 CFL2 DYNC1H1 PPP1R12A TP53BP1 HSP90AB1

2.27e-041049338int:CAPZB
InteractionCDK2 interactions

RFC1 ARID4A LMO7 CFL1 DYNC1H1 PPP1R12A HSP90AB1

2.30e-04783337int:CDK2
InteractionSND1 interactions

EIF5B IGF1R RFC1 PRPF40A HSP90AB1

2.35e-04347335int:SND1
InteractionBTF3 interactions

RFC1 LMO7 CFL1 DYNC1H1 CUX1 PPP1R12A HSP90AB1

2.60e-04799337int:BTF3
InteractionTUBB4B interactions

IKZF3 CAMSAP2 DYNC1H1 PPP1R12A PSMA3 HSP90AB1

2.62e-04560336int:TUBB4B
InteractionSYNPO interactions

LMO7 CFL1 CFL2 PPP1R12A

2.63e-04192334int:SYNPO
InteractionDCTN2 interactions

USO1 DYNC1H1 PPP1R12A PSMA3 HSP90AB1

2.64e-04356335int:DCTN2
InteractionTSHZ1 interactions

TSHZ2 HSP90AB1

2.69e-0415332int:TSHZ1
InteractionSFPQ interactions

IKZF3 LMO7 PRPF40A DYNC1H1 PSMA3 TP53BP1

2.70e-04563336int:SFPQ
InteractionTOLLIP interactions

CIR1 SRSF11 DYNC1H1 PPP1R12A TP53BP1

2.71e-04358335int:TOLLIP
InteractionSKA3 interactions

RFC1 CAMSAP2 PRPF40A TP53BP1

2.74e-04194334int:SKA3
InteractionSSH1 interactions

IGF1R CFL1 CFL2

2.91e-0479333int:SSH1
InteractionKCTD13 interactions

CAMSAP2 USO1 LMO7 PRPF40A CFL1 CFL2 DYNC1H1 PPP1R12A HSP90AB1

2.98e-041394339int:KCTD13
InteractionPAX6 interactions

SRSF11 IKZF3 ARID4B USP16 CUX1

3.00e-04366335int:PAX6
InteractionGATA2 interactions

IKZF3 ARID4B CUX1 PSMA3

3.02e-04199334int:GATA2
InteractionLDHA interactions

IKZF3 CFL1 CFL2 PSMA3 HSP90AB1

3.36e-04375335int:LDHA
InteractionZNF451 interactions

USO1 PRPF40A TP53BP1

3.36e-0483333int:ZNF451
InteractionSLFN11 interactions

EIF5B RFC1 POLR1A CENPF TP53BP1

3.40e-04376335int:SLFN11
InteractionTENT5A interactions

POLR1A DYNC1H1 DDX11

3.48e-0484333int:TENT5A
InteractionIQGAP1 interactions

LMO7 CFL1 CFL2 DYNC1H1 PPP1R12A HSP90AB1

3.50e-04591336int:IQGAP1
InteractionSMARCC1 interactions

IKZF3 ARID4B PRPF40A PPP1R12A TP53BP1

3.74e-04384335int:SMARCC1
InteractionKCNA3 interactions

EIF5B CCDC73 USO1 PRPF40A CFL1 DYNC1H1 HSP90AB1

4.38e-04871337int:KCNA3
InteractionH2BC3 interactions

RFC1 POLR1A USP16 CUX1 TP53BP1

4.83e-04406335int:H2BC3
InteractionDDX46 interactions

SRSF11 PRPF40A TP53BP1 HSP90AB1

4.96e-04227334int:DDX46
InteractionTESK2 interactions

CAMSAP2 CFL1 HSP90AB1

5.31e-0497333int:TESK2
InteractionCBX3 interactions

EIF5B IKZF3 RFC1 CUX1 PPP1R12A TP53BP1

5.61e-04646336int:CBX3
InteractionNPM1 interactions

SRSF11 IKZF3 RFC1 CENPF CFL1 PPP1R12A PSMA3 HSP90AB1

5.66e-041201338int:NPM1
InteractionWWTR1 interactions

LMO7 PRPF40A CUX1 PPP1R12A TP53BP1

5.75e-04422335int:WWTR1
InteractionHSP90B1 interactions

IGF1R POLR1A USO1 PPP1R12A PSMA3 HSP90AB1

5.79e-04650336int:HSP90B1
InteractionSIRPA interactions

EIF5B IGF1R HSP90AB1

5.80e-04100333int:SIRPA
InteractionHEXIM1 interactions

SRSF11 CFL1 CFL2 DYNC1H1 PSMA3 TP53BP1 HSP90AB1

5.81e-04913337int:HEXIM1
InteractionPOT1 interactions

CFL1 CFL2 TP53BP1 HSP90AB1

5.84e-04237334int:POT1
InteractionU2AF2 interactions

SRSF11 PRPF40A CFL1 DYNC1H1 TP53BP1 HSP90AB1

5.84e-04651336int:U2AF2
InteractionUBE2I interactions

IKZF3 CAMSAP2 TSHZ2 PRPF40A CFL2 TP53BP1

5.98e-04654336int:UBE2I
InteractionTNIP1 interactions

EIF5B POLR1A LMO7 PRPF40A CFL1 DYNC1H1 PPP1R12A HSP90AB1

6.18e-041217338int:TNIP1
InteractionMDM2 interactions

SRSF11 IGF1R USO1 LMO7 PSMA3 HSP90AB1

6.18e-04658336int:MDM2
InteractionPOLQ interactions

PRPF40A TP53BP1

6.44e-0423332int:POLQ
InteractionUNC5CL interactions

AXDND1 IGF1R

6.44e-0423332int:UNC5CL
Cytoband2q31.1

CIR1 CFAP210

1.89e-03843522q31.1
CytobandEnsembl 112 genes in cytogenetic band chr14q23

ARID4A PSMA3

4.45e-03130352chr14q23
CytobandEnsembl 112 genes in cytogenetic band chr2q31

CIR1 CFAP210

8.18e-03178352chr2q31
GeneFamilyAT-rich interaction domain containing

ARID4B ARID4A

1.47e-0415222418
CoexpressionMILI_PSEUDOPODIA_HAPTOTAXIS_UP

EIF5B SRSF11 FAM133A CAMSAP2 USP16 PRPF40A CFL2 PPP1R12A

4.09e-07534358MM1054
CoexpressionMILI_PSEUDOPODIA_HAPTOTAXIS_UP

EIF5B SRSF11 CAMSAP2 USP16 PRPF40A CFL2 PPP1R12A

5.01e-06523357M12707
CoexpressionGSE22886_IGM_MEMORY_BCELL_VS_BM_PLASMA_CELL_UP

ZKSCAN7 IKZF3 CFL1 PPP1R12A HSP90AB1

6.63e-06200355M4456
CoexpressionZHENG_CORD_BLOOD_C9_GRANULOCYTE_MACROPHAGE_PROGENITOR

ARID4A CENPF PRPF40A CFL1

9.54e-06100354M39218
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

IGF1R CBLB ARID4A CENPF CAMSAP2 CUX1 PPP1R12A TP53BP1

1.35e-05856358M4500
CoexpressionIKEDA_MIR30_TARGETS_UP

ARID4B ARID4A CFL2 PPP1R12A

1.72e-05116354M2379
CoexpressionIKEDA_MIR30_TARGETS_UP

ARID4B ARID4A CFL2 PPP1R12A

1.77e-05117354MM931
CoexpressionRODRIGUES_THYROID_CARCINOMA_POORLY_DIFFERENTIATED_UP

EIF5B RFC1 CENPF USP16 PRPF40A CFL2 PSMA3

1.93e-05644357M10501
CoexpressionFAN_OVARY_CL11_MURAL_GRANULOSA_CELL

SRSF11 IGF1R USO1 TSHZ2 PSMA3 HSP90AB1

2.44e-05444356M41713
CoexpressionERWIN_COHEN_BLOOD_LIVE_VACCINE_TC_83_AGE_23_48YO_VACCINATED_VS_CONTROL_14DY_UP

SRSF11 ARID4B CBLB USO1 USP16 PRPF40A PSMA3

2.92e-05687357M41022
CoexpressionFOURNIER_ACINAR_DEVELOPMENT_LATE_2

EIF5B SRSF11 CAMSAP2 PRPF40A DDX11

3.41e-05281355M4077
CoexpressionRODRIGUES_THYROID_CARCINOMA_ANAPLASTIC_UP

EIF5B RFC1 CENPF USO1 USP16 PRPF40A PSMA3

3.98e-05721357M10237
CoexpressionDEURIG_T_CELL_PROLYMPHOCYTIC_LEUKEMIA_DN

CIR1 IKZF3 ARID4B USP16 PPP1R12A

6.60e-05323355M12570
CoexpressionGSE4590_SMALL_VS_VPREB_POS_LARGE_PRE_BCELL_UP

IGF1R ARID4A CAMSAP2 CUX1

7.30e-05168354M6874
CoexpressionKIM_ALL_DISORDERS_CALB1_CORR_UP

CAMSAP2 USO1 DYNC1H1 PPP1R12A PSMA3 HSP90AB1

7.80e-05547356M2110
CoexpressionBUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_UP

CIR1 SRSF11 IGF1R ARID4B CBLB CUX1 HSP90AB1

9.08e-05822357M6782
CoexpressionNAKAYA_PBMC_FLUARIX_FLUVIRIN_AGE_18_50YO_CORRELATED_WITH_HAI_28DY_RESPONSE_AT_3DY_NEGATIVE

CIR1 SRSF11 CBLB LMO7 USP16

1.14e-04363355M41103
CoexpressionGSE21380_NON_TFH_VS_GERMINAL_CENTER_TFH_CD4_TCELL_DN

EIF5B SRSF11 ARID4A PPP1R12A

1.43e-04200354M7505
CoexpressionTABULA_MURIS_SENIS_MARROW_ERYTHROBLAST_AGEING

EIF5B SRSF11 CENPF HSP90AB1

1.52e-04203354MM3795
CoexpressionFAN_OVARY_CL15_SMALL_ANTRAL_FOLLICLE_GRANULOSA_CELL

ARID4B ARID4A USP16 PRPF40A PSMA3 HSP90AB1

1.90e-04644356M41717
CoexpressionLAKE_ADULT_KIDNEY_C5_PROXIMAL_TUBULE_EPITHELIAL_CELLS_STRESS_INFLAM

EIF5B CACNA1D SRSF11 ARID4A CUX1

2.18e-04417355M39224
CoexpressionSCHLOSSER_SERUM_RESPONSE_DN

CIR1 SRSF11 ARID4A USO1 PPP1R12A PSMA3

3.09e-04705356M1410
CoexpressionEIF4E_DN

ARID4B LMO7 TP53BP1

3.23e-04100353M2790
CoexpressionBUSSLINGER_GASTRIC_ISTHMUS_CELLS

EIF5B CENPF LMO7 CFL1 HSP90AB1

3.36e-04458355M40010
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN

CBLB CENPF CAMSAP2 CUX1 PPP1R12A

3.63e-04466355M13522
CoexpressionAtlasfacebase_RNAseq_e10.5_Emin_LatNas_2500_K3

EIF5B SRSF11 RFC1 ARID4B ARID4A CENPF USP16 PRPF40A CUX1 TP53BP1 HSP90AB1

2.42e-0612573411facebase_RNAseq_e10.5_Emin_LatNas_2500_K3
CoexpressionAtlasfacebase_RNAseq_e10.5_Emin_LatNas_2500

EIF5B SRSF11 RFC1 ARID4B ARID4A CENPF USP16 PRPF40A CUX1 TP53BP1 HSP90AB1

1.02e-0514593411facebase_RNAseq_e10.5_Emin_LatNas_2500
CoexpressionAtlasDevelopingKidney_e15.5_Pelvic Mesenchyme_emap-8241_k-means-cluster#3_top-relative-expression-ranked_500

CAMSAP2 CFL2 CUX1 PPP1R12A

3.45e-05116344gudmap_developingKidney_e15.5_Pelvic Mesenchyme_500_k3
CoexpressionAtlasDevelopingKidney_e15.5_Ureteral Smooth Musc_emap-28812_k-means-cluster#4_top-relative-expression-ranked_200

CFL2 CUX1 PPP1R12A

3.56e-0540343gudmap_developingKidney_e15.5_Ureteral Smooth Musc_200_k4
CoexpressionAtlasFacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_2500_k-means-cluster#5

CIR1 SRSF11 ARID4B ARID4A CENPF PRPF40A PPP1R12A

5.19e-05629347Facebase_RNAseq_e10.5_Maxillary Arch_2500_K5
CoexpressionAtlasFacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_1000_k-means-cluster#3

CIR1 SRSF11 ARID4B ARID4A PRPF40A PPP1R12A

5.68e-05432346Facebase_RNAseq_e10.5_Maxillary Arch_1000_K3
CoexpressionAtlasDevelopingKidney_e15.5_cortic collect duct_emap-28132_k-means-cluster#4_top-relative-expression-ranked_500

CAMSAP2 CFL2 CUX1 PPP1R12A

1.30e-04163344gudmap_developingKidney_e15.5_cortic collect duct_500_k4
CoexpressionAtlasDevelopingKidney_e15.5_ureter tip_flank cortic collct_emap-27752_k-means-cluster#5_top-relative-expression-ranked_1000

RFC1 CENPF CAMSAP2 PRPF40A CUX1

1.92e-04339345gudmap_developingKidney_e15.5_ureter tip_flank cortic collct_1000_k5
CoexpressionAtlasDevelopingKidney_e15.5_Pelvic Mesenchyme_emap-8241_k-means-cluster#5_top-relative-expression-ranked_1000

CAMSAP2 CFL2 CUX1 PPP1R12A

2.89e-04201344gudmap_developingKidney_e15.5_Pelvic Mesenchyme_1000_k5
CoexpressionAtlasDevelopingKidney_e15.5_Ureteral Smooth Musc_emap-28812_k-means-cluster#5_top-relative-expression-ranked_1000

CAMSAP2 CFL2 CUX1 PPP1R12A

3.00e-04203344gudmap_developingKidney_e15.5_Ureteral Smooth Musc_1000_k5
CoexpressionAtlasDevelopingKidney_e15.5_cortic collect duct_emap-28132_k-means-cluster#4_top-relative-expression-ranked_1000

CBLB CAMSAP2 CFL2 CUX1 PPP1R12A

3.05e-04375345gudmap_developingKidney_e15.5_cortic collect duct_1000_k4
CoexpressionAtlasDevelopingKidney_e15.5_Ureteral Smooth Musc_emap-28812_k-means-cluster#4_top-relative-expression-ranked_100

CUX1 PPP1R12A

3.33e-0417342gudmap_developingKidney_e15.5_Ureteral Smooth Musc_100_k4
CoexpressionAtlasDevelopingKidney_e15.5_Ureteral Smooth Musc_emap-28812_k-means-cluster#4_top-relative-expression-ranked_500

CAMSAP2 CFL2 CUX1

4.55e-0494343gudmap_developingKidney_e15.5_Ureteral Smooth Musc_500_k4
CoexpressionAtlasDevelopingKidney_e15.5_Pelvic Mesenchyme_emap-8241_top-relative-expression-ranked_500

CACNA1D CAMSAP2 CFL2 CUX1 PPP1R12A

4.70e-04412345gudmap_developingKidney_e15.5_Pelvic Mesenchyme_500
CoexpressionAtlasDevelopingKidney_e15.5_stage III -IV renal corpusc_emap-27945_k-means-cluster#4_top-relative-expression-ranked_500

CBLB CAMSAP2 CUX1

6.46e-04106343gudmap_developingKidney_e15.5_stage III -IV renal corpusc_500_k4
CoexpressionAtlasDevelopingKidney_e15.5_Endothelial cells_emap-29977_k-means-cluster#3_top-relative-expression-ranked_500

CAMSAP2 CUX1

7.30e-0425342DevelopingKidney_e15.5_Endothelial cells_emap-29977_k3_500
CoexpressionAtlasDevelopingGonad_e12.5_epididymis_emap-29139_k-means-cluster#1_top-relative-expression-ranked_1000

EIF5B RFC1 POLR1A HSP90AB1

7.74e-04261344gudmap_developingGonad_e12.5_epididymis_k1_1000
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_1000

EIF5B SRSF11 CFAP210 CENPF PRPF40A CUX1 HSP90AB1

8.00e-04983347Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_1000
CoexpressionAtlasFacebaseRNAseq_e9.5_Mandibular Arch_top-relative-expression-ranked_1000

CIR1 SRSF11 ARID4A CFL1 PPP1R12A PSMA3 TP53BP1

8.00e-04983347Facebase_RNAseq_e9.5_Mandibular Arch_1000
CoexpressionAtlasFacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_1000

CIR1 SRSF11 ARID4B ARID4A CENPF PRPF40A PPP1R12A

8.30e-04989347Facebase_RNAseq_e10.5_Maxillary Arch_1000
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000

SRSF11 CFAP210 ARID4B ARID4A CENPF CUX1 HSP90AB1

8.30e-04989347Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000
CoexpressionAtlasFacebaseRNAseq_e8.5_Floor Plate_top-relative-expression-ranked_2500_k-means-cluster#1

CIR1 EIF5B ARID4A CENPF PRPF40A

8.44e-04469345Facebase_RNAseq_e8.5_Floor Plate_2500_K1
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

IKZF3 ARID4B CBLB DYNC1H1 TP53BP1

3.54e-07188355ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCellH1299-infected-SARSCoV2|infected / Cell line, Condition and Strain

CIR1 EIF5B SRSF11 ARID4A PRPF40A

4.46e-071973550fa3e4cf93e77d78b1f97b906c5b13ca741ae17e
ToppCell(10)_Ciliated-(2)_GFP_FOXI1|(10)_Ciliated / shred by cell type by condition

EIF5B CFAP210 ARID4B USP16 PRPF40A

4.69e-0719935561b1ed2db71b96157b92b7535d1955a4033098da
ToppCell(00)_Basal-(2)_GFP_FOXI1|(00)_Basal / shred by cell type by condition

EIF5B RFC1 ARID4A USP16 PRPF40A

4.69e-0719935519674e1eaeb51e4196d847cb62aa437c852951d3
ToppCell(04)_Interm._basal>secr.-(2)_GFP_FOXI1|(04)_Interm._basal>secr. / shred by cell type by condition

EIF5B ARID4B LMO7 USP16 PRPF40A

4.69e-0719935553ca3861f9e00dab3f3fbefb0837857ee39ab084
ToppCell(09)_Interm._secr.>cil.-(2)_GFP_FOXI1|(09)_Interm._secr.>cil. / shred by cell type by condition

EIF5B ARID4B LMO7 USP16 PRPF40A

4.69e-07199355fc680f85ebd3bab4c72876a19a461b0afb5f51ce
ToppCell(01)_IL1RL1+-(2)_GFP_FOXI1|(01)_IL1RL1+ / shred by cell type by condition

EIF5B RFC1 ARID4A LMO7 USP16

4.69e-07199355a2f7d0cabf35b80fe239fae34a77bf9344d5d743
ToppCellCOPD-Lymphoid-T_Regulatory|World / Disease state, Lineage and Cell class

IKZF3 ARID4B CBLB TSHZ2

1.18e-0518035451a12fbad5fa7bb12e6d616a02ff9b5141e2b063
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1|TCGA-Pancreas / Sample_Type by Project: Shred V9

ARID4B ARID4A PRPF40A PPP1R12A

1.34e-0518635403db813598b67b1e08f759758a1c2023396921fa
ToppCelldroplet-Bladder-nan|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EIF5B ARID4B PRPF40A HSP90AB1

1.37e-05187354663991a8afe652e92363b64bcbd68c14d0307f0e
ToppCelldroplet-Tongue-nan|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EIF5B SRSF11 ARID4B PRPF40A

1.40e-05188354d62cc37e86b7b186e53aeb7f421c4e5ee28f23bd
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25|PBMC_fresh-frozen / Compartment, severity and other cell annotations on 10x 3' data (130k)

CIR1 SRSF11 CFAP210 ARID4B

1.49e-051913541ecd9849d14d5ebf3daf610e83fb50820cafd3ed
ToppCell10x5'-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8|lymph-node_spleen / Manually curated celltypes from each tissue

SRSF11 ARID4B CBLB TSHZ2

1.52e-0519235447646d7e4990be85072987f92bf18d52f8da752e
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CACNA1D IGF1R LMO7 CUX1

1.55e-051933543866667dd221612589ae50f5c52f73a183a49ce6
ToppCellCOVID-19_Mild-PLT_4|World / Disease Group and Platelet Clusters

CIR1 ARID4B ARID4A PPP1R12A

1.55e-0519335498a52523aa1efd5d14a2878ed106828a80a33aa2
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c01-LEF1|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

IGF1R TSHZ2 LMO7 HSP90AB1

1.55e-051933544e78ddc96d8e403a21c4a303b1f26512d2ac91e8
ToppCellCOVID-19_Severe-PLT_4|World / Disease Group and Platelet Clusters

CIR1 ARID4B ARID4A PPP1R12A

1.65e-05196354ad43efdd4d73b6615f65f06a315b33576e317473
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

IKZF3 CBLB CFL2 HSP90AB1

1.65e-05196354c225c8eb2fe9a10f0cf574c7d8b6206887aac2df
ToppCellCOVID_non-vent-Lymphocytic-T_cell-CD4+_Naive_T_cell|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

SRSF11 IGF1R TSHZ2 HSP90AB1

1.68e-05197354836dd8110d5689f944ad1d301def38c32278b5b5
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-myeloid-myeloid_monocytic-leukocyte|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

IKZF3 CENPF TSHZ2 PPP1R12A

1.68e-05197354d968d7d5608b175bb567ea3a315bf473ec3be459
ToppCellCOVID-19_Severe-PLT_4|COVID-19_Severe / Disease Group and Platelet Clusters

CIR1 ARID4B ARID4A PPP1R12A

1.71e-05198354abfddbee99ef8c7719e6e6f62571e9be030e4acf
ToppCellCOVID-19_Mild-PLT_4|COVID-19_Mild / Disease Group and Platelet Clusters

CIR1 ARID4B ARID4A PPP1R12A

1.71e-051983543d8c33dba759df0974aeb2b9a6b5167ae7a18e1f
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Parietal_and_Temporal-6|World / Primary Cells by Cluster

ARID4A LMO7 CFL1 HSP90AB1

1.75e-051993541b1bccf4293f11048709d15a3c892c0edf3da3d2
ToppCellCOVID_vent-Lymphocytic-T_cell-CD4+_Naive_T_cell|COVID_vent / Disease condition, Lineage, Cell class and subclass

IGF1R TSHZ2 LMO7 HSP90AB1

1.75e-05199354885bc902b6e2af0b61e452c4154160cd3f1cf98e
ToppCell(03)_KRT6B+-(2)_GFP_FOXI1|(03)_KRT6B+ / shred by cell type by condition

EIF5B RFC1 LMO7 USP16

1.75e-05199354c425e7975f492ed5cfcca022248adb627e1d27d4
ToppCell(05)_Secretory-(2)_GFP_FOXI1|(05)_Secretory / shred by cell type by condition

EIF5B LMO7 USP16 PRPF40A

1.75e-05199354d72d87e1e530ed894c0ad5e7b5b2b1d6b59fa098
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Parietal_and_Temporal|World / Primary Cells by Cluster

ARID4A LMO7 CFL1 HSP90AB1

1.75e-051993544bee94c116c0da5eba951cb4cea7cc9dcdd6e30f
ToppCellmegakaryocytic-CD34+_Megakaryoblast|megakaryocytic / Lineage and Cell class

EIF5B SRSF11 PRPF40A HSP90AB1

1.75e-0519935499a65887d3c8a2cde26693dd74404b101bba9d58
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CACNA1D FAM133A TSHZ2

2.20e-041503537a9d6a7ff8000e9a061e1b586e4c258cc91a2a09
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CACNA1D FAM133A TSHZ2

2.20e-04150353e5b843cb2bc847f6cab4cbec0a2a6a72fac50fee
ToppCellLPS-antiTNF-Epithelial_alveolar-Mes-Like-AT2_Progenitor|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

AXDND1 CENPF FAM133A

2.24e-04151353c06a54afe918b14f885d6a85fbcf81e80f33afae
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c12-FOXP3|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CCDC73 CENPF CAMSAP2

3.12e-04169353c8691c4f707d46b2865fe46eabe24ea4d03c7b43
ToppCell3'_v3-Lung-Lymphocytic_T_CD4/8-lo|Lung / Manually curated celltypes from each tissue

IKZF3 CBLB CENPF

3.23e-04171353dfd4a15ab68ef5a9a1954b1b1540ae04017885a6
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-immature_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IKZF3 KCNU1 CFL1

3.34e-04173353e944ea3a0a368f856efacbda4600605cf751dd9c
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-immature_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IKZF3 KCNU1 CFL1

3.34e-0417335385fa5918e9c1f6bb4757e3350cfc71ee75c55640
ToppCellfacs-Tongue-nan-24m-Epithelial-basal_cell_of_epidermis|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CENPF CFL1 HSP90AB1

3.45e-04175353758a1796b823118ce52f989ef5e1076f8c8ac4c5
ToppCelldroplet-Limb_Muscle-MUSCLE-30m|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARID4B LMO7 HSP90AB1

3.63e-0417835301dafd19de04eff459253eaa9a35debf8f3deedf
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-4M-Neuronal-ventral_progenitors_and_neurons_2|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.

KCNU1 CENPF CFL1

3.69e-04179353d95367d689732ab2653e8d70d8d8e5eb15ae6eef
ToppCellfacs-Large_Intestine-Proximal-18m-Epithelial-epithelial_cell_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EIF5B CENPF HSP90AB1

3.81e-041813539fce5eee75684a7ecac6996e26e9215bc95098b2
ToppCellfacs-Large_Intestine-Proximal-18m-Epithelial-Lgr5-_amplifying_undifferentiated_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EIF5B CENPF HSP90AB1

3.81e-04181353ad97e802e934738ddece675232a72308db2da256
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c01-LEF1|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

IGF1R TSHZ2 CFL2

4.00e-041843535350b58aa9979631228835d11eb45ddf81d08bff
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature3_(17)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

CACNA1D CBLB TSHZ2

4.19e-04187353a9316e2818217ec5feae9cf8816f7249803caee6
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Stem-like-OPC-like-OPC-like_Prolif-E|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

EIF5B KCNU1 CENPF

4.26e-041883530476d7ee3e0ce78c3c5b111e9ade01098f9ea7ec
ToppCell3'_v3-Lung-Lymphocytic_T_CD4-Trm_Th1/Th17|Lung / Manually curated celltypes from each tissue

IKZF3 ARID4B HSP90AB1

4.33e-04189353f43960506ed3e699e910ec7711c1113e2e9b80d1
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_T_CD4/8-lo|lymph-node_spleen / Manually curated celltypes from each tissue

IKZF3 CBLB CENPF

4.39e-041903534225bfa10a6fb909a3ba8ac26f3541c390b46737
ToppCellPCW_13-14|World / Celltypes from embryonic and fetal-stage human lung

CACNA1D IGF1R CBLB

4.39e-0419035362a3ec1ae0829602b0569cc051210551644f1d46
ToppCellSevere-Lymphoid-T-NK|Severe / Condition, Lineage, Cell class and cell subclass

IKZF3 CBLB CENPF

4.39e-0419035360642de433f84fa2cecd796c3a1a4aab9219d3db
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

IGF1R TSHZ2 CFL2

4.46e-04191353d9a6f61fcda4f5352488f7f55cb9b57aeacc717f
ToppCellCOVID-19-T_cells|COVID-19 / group, cell type (main and fine annotations)

IKZF3 CBLB CENPF

4.46e-041913537f64add931b64b8d35836fa6bee9ebab593844d3
ToppCell3'_v3-Lung-Lymphocytic_T_CD4|Lung / Manually curated celltypes from each tissue

IKZF3 ARID4B TSHZ2

4.53e-04192353fd19cd0b5330448bef8debd753285adbc8b958a2
ToppCelldroplet-Thymus-nan-3m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CENPF CFL1 CUX1

4.53e-04192353041124dd5c24c1eb188d2560ba606422c0b215c5
ToppCelldroplet-Thymus-nan-3m|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CENPF CFL1 CUX1

4.53e-04192353d9e61b2722aa81e4f6e11865a04f2f1e75b794ab
ToppCellAT1_cells-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

ARID4A LMO7 CFL2

4.53e-041923530444f9e9cef7403e220e862b5a787443d3f5c9ac
ToppCellH1299-infected|H1299 / Cell line, Condition and Strain

EIF5B SRSF11 CENPF

4.53e-041923539cf8049bdc3e0f81ce69042beac72b08d8f38b4e
ToppCellILEUM-inflamed-(1)_Th17_Trm|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

ARID4B CBLB CFL1

4.60e-041933530663c57e1b8b8dd70d617d029fc7bdbbda8c1208
ToppCellCOVID-19_Convalescent-CD4+_T_naive|COVID-19_Convalescent / Disease condition and Cell class

IGF1R TSHZ2 LMO7

4.60e-04193353346caaf288217acaf232060629ce964a07f63432
ToppCelldroplet-Tongue-nan-3m|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SRSF11 PRPF40A CFL1

4.60e-04193353cba070019db30604ebddb610eedf92e48221ac58
ToppCellCF-Lymphoid|CF / Disease state, Lineage and Cell class

EIF5B IKZF3 CBLB

4.60e-0419335311de07d13a7da223990b56fa89ba7fc1c3dd0122
ToppCellHealthy/Control-CD4+_T_naive|Healthy/Control / Disease group and Cell class

IGF1R TSHZ2 LMO7

4.60e-04193353f5face746df3517c86d72e31ba8f1b78c4c6b481
ToppCelldroplet-Tongue-nan-3m-Epithelial|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SRSF11 PRPF40A CFL1

4.60e-0419335307ddb9525b686c31fa7df4286557d1e58f7ead52
ToppCellHealthy/Control-CD4+_T_naive|World / Disease group and Cell class

IGF1R TSHZ2 LMO7

4.60e-041933536218e6cbe44d92bb98d42ef2f5e18ab7a683b100
ToppCellCOVID-19_Convalescent-PLT_4|COVID-19_Convalescent / Disease Group and Platelet Clusters

CIR1 ARID4B PPP1R12A

4.67e-04194353ce1fad4e76a87f0c35e430ed1f2262395df882fd
ToppCelldroplet-Limb_Muscle-MUSCLE|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARID4B LMO7 PPP1R12A

4.67e-04194353e3d63874111d1e8da3977329426e4dcf68d6de87
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

CACNA1D CBLB TSHZ2

4.67e-04194353b1bb0f846d2865efdd9bc8842b16b9d069785882
ToppCellsevere_COVID-19-CD4+_T_naive|severe_COVID-19 / disease group, cell group and cell class (v2)

TSHZ2 LMO7 HSP90AB1

4.67e-041943534b86f3cc173ea779399d5b3598b45b25f60a4395
ToppCell(1)_T_cells-(1)_T_CD8_activated|(1)_T_cells / Spleen cell shreds - cell class (v1) and cell subclass (v1)

IKZF3 CBLB CFL1

4.67e-04194353e3f288b58525c1f34db4459d3e83e0df695adfc7
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia/MHC-E|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CIR1 EIF5B RFC1

4.67e-041943538985095f291c1b54e45f4edece49aa26e8c8b732
ToppCell10x_3'_v3-blood_(10x_3'_v3)-lymphocytic-T_lymphocytic-naive_thymus-derived_CD4-positive,_alpha-beta_T_cell|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

TSHZ2 LMO7 HSP90AB1

4.74e-041953534e114f6399863406bd87220dea7fb7dfd08824bd
ToppCellmild-dn_T|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

IKZF3 CBLB CENPF

4.74e-04195353158f0f229bad71cc9b06b7399168982bbbbd1d47
ToppCell(1)_T_cells-(1)_T_CD4_naive|(1)_T_cells / Spleen cell shreds - cell class (v1) and cell subclass (v1)

IGF1R TSHZ2 LMO7

4.74e-04195353d3fa551bc6f5ee5890af1040415e61ecd5d46201
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature3_(17)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

CACNA1D CBLB TSHZ2

4.74e-041953531cdf5f296029ae424d9dba42e86a6d111e4896e6
ToppCell10x_5'_v1-Non-neoplastic-Lymphoid-CD4/CD8-Stress_sig-F_2|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

IKZF3 ARID4B HSP90AB1

4.81e-04196353ea8eceacc5d5e1a22b77c31e7c45985dc7bb15de
ToppCellSevere-Lymphoid-T-Treg|Severe / Condition, Lineage, Cell class and cell subclass

IKZF3 CBLB TSHZ2

4.81e-0419635329d4db6816fead2ad9136ef824e0775463b02159
ToppCellCOVID-19-Epithelial_cells-Cycling_epithelial|COVID-19 / group, cell type (main and fine annotations)

IKZF3 CENPF CFL1

4.81e-04196353ac55fff652bad06eab502645bf64126625763ab3
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

IGF1R CBLB TSHZ2

4.81e-04196353c4e7133c609bcbc48c4947ea0aa1a7d9d7251b04
ToppCellControl-B_naive-8|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)

ARID4B CBLB CFL1

4.81e-0419635354074da84000e4749ade8acc542f05a275bf829f
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c03-GZMK|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

IKZF3 CBLB CFL1

4.81e-0419635317f17edadafdad9f24e88d708d7e1c765503131c
ToppCellILEUM-non-inflamed-(8)_Fibroblast-(8)_Smooth_muscle_cells|(8)_Fibroblast / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

TSHZ2 CFL1 CFL2

4.88e-041973534e0c3ea4f4a04a41532806edf3bccf7845c86fa5
ToppCellCOVID-19_Severe-Lymphoid_T/NK-CD4+_T_naive|COVID-19_Severe / Disease group, lineage and cell class

IGF1R TSHZ2 HSP90AB1

4.88e-0419735307f74bdadfd28e1d55b3f4a3bf87d5dd65a2e9c5
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature3_(17)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

CACNA1D CBLB TSHZ2

4.88e-0419735331a1852911bda38543916585fda34255fd62a134
ToppCellCOVID-19_Mild|World / Disease group, lineage and cell class

CIR1 ARID4B USP16

4.88e-041973535c33454b10023decd2f5ccda9229b6512659711e
ToppCellsevere-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

SRSF11 ARID4B TSHZ2

4.88e-0419735357ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCellPBMC-Severe-Lymphocyte-T/NK-CD4+_T-CD4+_T_naive-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IGF1R TSHZ2 HSP90AB1

4.88e-04197353258dfe69b5faeaee709422f873b144ca5e4a6452
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

IKZF3 CBLB TSHZ2

4.88e-04197353268ca646f4a7466709c2c8b6ca56cf1344f3ef3e
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

IKZF3 CBLB TSHZ2

4.88e-0419735359b1fb93a39dcf8c994d2b7dc2906dae74c57527
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature1_(0)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

CACNA1D CBLB TSHZ2

4.88e-041973530034bae02ee7fcfea520d453ca3c842ab6963b12
ToppCellPBMC-Severe-Lymphocyte-T/NK-CD4+_T-CD4+_T_naive|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IGF1R TSHZ2 HSP90AB1

4.88e-041973539f0d91bb7aec4f2442259eca1ddf7905f8d40e9b
ToppCellILEUM-inflamed-(3)_MNP-(3)_DC1|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

EIF5B CENPF CFL1

4.88e-041973539a3d0b7f4788487d024d56bc776a2fd1149f50d5
ToppCellBL-critical-LOC-Lymphoid-CTL|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

IKZF3 RFC1 CBLB

4.88e-04197353fb70918867fbd111bb192a797dcafed5f39ea299
ToppCellPBMC-Severe-Lymphocyte-T/NK-CD4+_T-CD4+_T_naive|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

IGF1R TSHZ2 HSP90AB1

4.88e-04197353bf80e39cd68fd5bb85c8726d4f82648391de74ad
ToppCellPBMC-Severe-Lymphocyte-T/NK-CD4+_T-CD4+_T_naive-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

IGF1R TSHZ2 HSP90AB1

4.88e-04197353296b27348ca7e9acf746f752cf810e4e5baea76c
ToppCellCOVID-19_Severe-CD4+_T_naive|COVID-19_Severe / Disease condition and Cell class

IGF1R TSHZ2 HSP90AB1

4.88e-04197353ac26672bd2cb3bc9a11206d8da203bafec3931f6
ToppCellhealthy_donor-Lymphocytic-T_cell-CD4+_Naive_T_cell|healthy_donor / Disease condition, Lineage, Cell class and subclass

IGF1R TSHZ2 LMO7

4.88e-04197353cf72160f03105876641fa6fdc7405e339eb084c7
ToppCellmild-dn_T|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

IKZF3 CBLB CENPF

4.88e-0419735307a1f59c83b748825e0708cd1cc7b63a2cb856cc
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature1_(0)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

CACNA1D CBLB TSHZ2

4.88e-0419735311a4c417f035e554431a8f03be13b5eefa3530c0
ToppCellControl-B_naive-8|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

ARID4B CBLB CFL1

4.88e-04197353925bf0d38e4ce279fa45f455546ebd199282c0df
ToppCellBL-critical-LOC-Lymphoid|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

IKZF3 RFC1 CBLB

4.95e-041983531c0227e58a64c0bf509bfb9578fb91277316b120
ToppCellSigmoid-T_cell-Treg|T_cell / Region, Cell class and subclass

IKZF3 CENPF TSHZ2

4.95e-04198353e2d2f9f209f77d0c48cfe3e9902c0ae0795511b2
ToppCellCaecum-T_cell-Tcm|T_cell / Region, Cell class and subclass

IGF1R TSHZ2 LMO7

4.95e-04198353f889ee80c641540fd8db9eaefcd16aa51ddb2c01
ToppCell(11)_FOXN4+-(2)_GFP_FOXI1|(11)_FOXN4+ / shred by cell type by condition

CENPF USP16 PRPF40A

4.95e-0419835376d40b8c2f8399725b3a62ee2ae0896559cf91eb
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

IKZF3 CBLB DYNC1H1

1.48e-0449233GAVISH_3CA_METAPROGRAM_CD8_T_CELLS_CHROMATIN
DrugAir Pollutants

CIR1 CACNA1D RFC1 ARID4B ARID4A CENPF LMO7 PRPF40A TP53BP1

5.67e-06917349ctd:D000393
Drugirinotecan HCl; Down 200; 100uM; MCF7; HT_HG-U133A

IGF1R ARID4B CBLB CENPF PPP1R12A

5.72e-061743457530_DN
DrugLovastatin

IGF1R CENPF CFL1 PSMA3 HSP90AB1

1.46e-05211345ctd:D008148
DrugNSC226080

EIF5B IGF1R ARID4B ARID4A PRPF40A CUX1 PSMA3 HSP90AB1

1.53e-05782348CID000005040
Diseaseattention deficit hyperactivity disorder, substance abuse, antisocial behaviour measurement

CACNA1D IGF1R KCNU1 CCDC73 ARID4A TSHZ2 CUX1

1.97e-05801327EFO_0003888, EFO_0007052, MONDO_0002491
Diseasemuscular atrophy (biomarker_via_orthology)

CFL1 HSP90AB1

4.54e-0429322DOID:767 (biomarker_via_orthology)
Diseaseresponse to angiotensin receptor blocker

CACNA1D POLR1A

4.86e-0430322EFO_0010735
DiseaseDuchenne muscular dystrophy (implicated_via_orthology)

CACNA1D KCNU1

7.01e-0436322DOID:11723 (implicated_via_orthology)
DiseaseMalignant neoplasm of breast

IGF1R CENPF CFL1 CFL2 CUX1 TP53BP1

9.22e-041074326C0006142
Diseaseinsulin resistance

CACNA1D KCNU1

1.88e-0359322EFO_0002614
Diseasealcohol consumption measurement

EIF5B CACNA1D RFC1 ARID4A TSHZ2 CUX1

1.94e-031242326EFO_0007878
DiseaseMammary Carcinoma, Human

IGF1R CENPF CFL1 TP53BP1

2.40e-03525324C4704874
DiseaseMammary Neoplasms, Human

IGF1R CENPF CFL1 TP53BP1

2.40e-03525324C1257931
DiseaseMicrocephaly

CENPF DYNC1H1

2.41e-0367322C0025958
DiseaseJT interval

CACNA1D IGF1R CUX1

2.43e-03248323EFO_0007885
DiseaseMammary Neoplasms

IGF1R CENPF CFL1 TP53BP1

2.43e-03527324C1458155
DiseaseBreast Carcinoma

IGF1R CENPF CFL1 TP53BP1

2.62e-03538324C0678222
DiseaseAlzheimer's disease (is_marker_for)

IGF1R BARHL1 DYNC1H1

2.69e-03257323DOID:10652 (is_marker_for)
DiseaseEndometrial Carcinoma

IGF1R CUX1

2.78e-0372322C0476089
Diseaseserum gamma-glutamyl transferase measurement

IKZF3 IGF1R CBLB USP16 TP53BP1

2.83e-03914325EFO_0004532
Diseasepsychotic symptoms

ARID4B TSHZ2

2.93e-0374322EFO_0005940

Protein segments in the cluster

PeptideGeneStartEntry
EDTDYEEDEVTKKRK

ARID4B

791

Q4LE39
DATYETKESKKEDLV

CFL1

86

P23528
KDVDDDYETAEKKEN

ARID4A

501

P29374
DSEYKVKEEGDREIS

BARHL1

151

Q9BZE3
YLEKEREKEISDDEA

HSP90AB1

216

P08238
SESDYEEDVQAKKKR

FAM133A

196

Q8N9E0
KTKYDEETTAKADEI

CUX1

226

Q13948
EKTRDPVEEDDDEYK

CBLB

696

Q13191
DATYETKESKKEDLV

CFL2

86

Q9Y281
EAEKQAEKEEAEYRK

IGF1R

706

P08069
SYTSDLQKKKEEREE

LMO7

751

Q8WWI1
AKENERKTSDEVYDE

KCNU1

1126

A8MYU2
EYESDEEKKVASRVD

DDX11

201

Q96FC9
VQTEKEEKEEARSKY

PRPF40A

446

O75400
EEKEEARSKYKEAKE

PRPF40A

451

O75400
LKETLEEKTKEADEY

CENPF

2846

P49454
SFKEDEEESKEDRKL

AXDND1

846

Q5T1B0
SDTEYREKEEKKEGS

CCDC73

436

Q6ZRK6
DEDDLAYAETEKKTR

DYNC1H1

4351

Q14204
KDEYSERDENVLKSE

IKZF3

61

Q9UKT9
EEEKRSSDSDYEQAK

BMP2KL

51

Q5H9B9
NKVTIDDYREEDEDK

CACNA1D

801

Q01668
DEKVYTDRAKEKESQ

CAMSAP2

821

Q08AD1
KAIYKSSEEDKKEEE

USO1

626

O60763
KRKEKQEEEVDYESE

POLR1A

1416

O95602
KKKRIIYDSDSESEE

RFC1

61

P35251
DDDRTKEERAYDKAK

EIF5B

596

O60841
EEEEERRKKYEEKDA

CFAP210

226

Q0VFZ6
ENKEKEETEGETEYK

CIR1

81

Q86X95
EEEKDNDSYIKERSD

USP16

416

Q9Y5T5
DEEEQGYDSEKEKKE

SRSF11

426

Q05519
AEKYAKESLKEEDES

PSMA3

236

P25788
RLDTKEEKSVEYEGD

TP53BP1

801

Q12888
ETSKDEKVVKSEDYE

TSHZ2

471

Q9NRE2
ITDEDKKKSTKDRYD

ZKSCAN7

341

Q9P0L1
EEKKESETSREDEYK

PPP1R12A

741

O14974