Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	regulation of protein tyrosine kinase activity	RELN CBLC CBL ITGB3 DLG3	4.00e-05	69	114	5	GO:0061097
GeneOntologyBiologicalProcess	positive regulation of synaptic vesicle fusion to presynaptic active zone membrane	DOC2A ERC1 DOC2B	4.52e-05	13	114	3	GO:0031632
GeneOntologyBiologicalProcess	positive regulation of synaptic vesicle membrane organization	DOC2A ERC1 DOC2B	4.52e-05	13	114	3	GO:1901634
GeneOntologyBiologicalProcess	calcium-dependent activation of synaptic vesicle fusion	DOC2A ERC1 DOC2B	4.52e-05	13	114	3	GO:0099502
GeneOntologyBiologicalProcess	regionalization	RELN CDX4 DYNC2H1 RFX4 ZEB2 RNF220 HOXB5 NEUROD1 LRP6 DLX2 IRX2	6.94e-05	478	114	11	GO:0003002
GeneOntologyBiologicalProcess	telencephalon development	RELN RFX4 ZEB2 NEUROD1 LMX1A LRP6 DLX2 MDGA1 TNR	9.59e-05	332	114	9	GO:0021537
GeneOntologyBiologicalProcess	positive regulation of DNA-binding transcription factor activity	RELN HDAC4 ERC1 IRAK2 RNF220 NEUROD1 NEUROD2 LRP6	1.02e-04	261	114	8	GO:0051091
GeneOntologyBiologicalProcess	receptor-mediated endocytosis	ABCA2 RAB31 MYO6 CBL ITGB3 RNF220 MTMR2 LRP1 LRP6	1.07e-04	337	114	9	GO:0006898
GeneOntologyBiologicalProcess	pattern specification process	RELN CDX4 DYNC2H1 RFX4 ZEB2 RNF220 HOXB5 NEUROD1 LRP6 DLX2 IRX2	1.61e-04	526	114	11	GO:0007389
GeneOntologyBiologicalProcess	regulation of synaptic vesicle fusion to presynaptic active zone membrane	DOC2A ERC1 DOC2B	1.75e-04	20	114	3	GO:0031630
GeneOntologyBiologicalProcess	regulation of synaptic vesicle membrane organization	DOC2A ERC1 DOC2B	1.75e-04	20	114	3	GO:1901632
GeneOntologyBiologicalProcess	positive regulation of vesicle fusion	DOC2A ERC1 DOC2B	1.75e-04	20	114	3	GO:0031340
GeneOntologyBiologicalProcess	regulation of axon extension involved in regeneration	LRP1 TNR	1.80e-04	4	114	2	GO:0048690
GeneOntologyBiologicalProcess	postsynaptic endocytosis	MYO6 ITGB3 RNF220 LRP1	1.81e-04	51	114	4	GO:0140239
GeneOntologyBiologicalProcess	postsynaptic neurotransmitter receptor internalization	MYO6 ITGB3 RNF220 LRP1	1.81e-04	51	114	4	GO:0098884
GeneOntologyBiologicalProcess	regulation of receptor-mediated endocytosis	ABCA2 CBL ITGB3 RNF220 MTMR2 LRP1	2.31e-04	156	114	6	GO:0048259
GeneOntologyBiologicalProcess	pallium development	RELN ZEB2 NEUROD1 LMX1A LRP6 DLX2 MDGA1	2.36e-04	222	114	7	GO:0021543
GeneOntologyBiologicalProcess	neurotransmitter receptor internalization	MYO6 ITGB3 RNF220 LRP1	2.98e-04	58	114	4	GO:0099590
GeneOntologyBiologicalProcess	axon extension involved in regeneration	LRP1 TNR	3.00e-04	5	114	2	GO:0048677
GeneOntologyBiologicalProcess	regulation of sprouting of injured axon	LRP1 TNR	3.00e-04	5	114	2	GO:0048686
GeneOntologyBiologicalProcess	hippocampus development	RELN ZEB2 NEUROD1 LMX1A DLX2	3.35e-04	108	114	5	GO:0021766
GeneOntologyBiologicalProcess	forebrain development	RELN DYNC2H1 RFX4 ZEB2 NEUROD1 LMX1A LRP6 DLX2 MDGA1 TNR	3.86e-04	489	114	10	GO:0030900
GeneOntologyCellularComponent	vacuole	DOC2A ABCA2 WIPI1 MYO6 HLA-DOA NAGA PSMD1 MEAK7 MFSD12 GLB1 MTMR2 LRP1 CHID1 WDFY3 TECPR1	1.32e-04	913	114	15	GO:0005773
GeneOntologyCellularComponent	cytoplasmic vesicle membrane	DOC2A ABCA2 WIPI1 RAB31 LZTR1 MYO6 HLA-DOA IRAK2 ITGB3 MFSD12 NBEAL2 SEC24B MTMR2 LRP1 LRP6 PLIN3 DSE DOC2B	2.47e-04	1307	114	18	GO:0030659
GeneOntologyCellularComponent	vesicle membrane	DOC2A ABCA2 WIPI1 RAB31 LZTR1 MYO6 HLA-DOA IRAK2 ITGB3 MFSD12 NBEAL2 SEC24B MTMR2 LRP1 LRP6 PLIN3 DSE DOC2B	2.91e-04	1325	114	18	GO:0012506
GeneOntologyCellularComponent	vacuolar membrane	ABCA2 WIPI1 MYO6 HLA-DOA MEAK7 MFSD12 MTMR2 LRP1 WDFY3 TECPR1	4.61e-04	507	114	10	GO:0005774
Domain	Doc2	DOC2A DOC2B	3.63e-05	2	113	2	IPR014638
Domain	Adaptor_Cbl_EF_hand-like	CBLC CBL	1.08e-04	3	113	2	IPR014741
Domain	Adaptor_Cbl_SH2-like	CBLC CBL	1.08e-04	3	113	2	IPR014742
Domain	Adaptor_Cbl	CBLC CBL	1.08e-04	3	113	2	IPR024162
Domain	Cbl_PTB	CBLC CBL	1.08e-04	3	113	2	IPR024159
Domain	Cbl_N2	CBLC CBL	1.08e-04	3	113	2	PF02761
Domain	Cbl_N3	CBLC CBL	1.08e-04	3	113	2	PF02762
Domain	Cbl_N	CBLC CBL	1.08e-04	3	113	2	PF02262
Domain	Adaptor_Cbl_N_hlx	CBLC CBL	1.08e-04	3	113	2	IPR003153
Domain	CBL_PTB	CBLC CBL	1.08e-04	3	113	2	PS51506
Domain	-	CBLC CBL	1.08e-04	3	113	2	1.20.930.20
Domain	Neurogenic_DUF	NEUROD1 NEUROD2	2.16e-04	4	113	2	IPR022575
Domain	Neuro_bHLH	NEUROD1 NEUROD2	2.16e-04	4	113	2	PF12533
Domain	TF_bHLH_NeuroD	NEUROD1 NEUROD2	2.16e-04	4	113	2	IPR016637
Domain	DUF4704	NBEAL2 WDFY3	3.59e-04	5	113	2	IPR031570
Domain	DUF4704	NBEAL2 WDFY3	3.59e-04	5	113	2	PF15787
Domain	PH_BEACH	NBEAL2 WDFY3	5.36e-04	6	113	2	PF14844
Domain	HOMEOBOX_1	CDX4 EVX1 ZEB2 HOXB5 LMX1A DLX2 IRX2	5.84e-04	236	113	7	PS00027
Domain	HOX	CDX4 EVX1 ZEB2 HOXB5 LMX1A DLX2 IRX2	5.99e-04	237	113	7	SM00389
Domain	HOMEOBOX_2	CDX4 EVX1 ZEB2 HOXB5 LMX1A DLX2 IRX2	6.29e-04	239	113	7	PS50071
Domain	Homeobox_dom	CDX4 EVX1 ZEB2 HOXB5 LMX1A DLX2 IRX2	6.29e-04	239	113	7	IPR001356
Domain	EGF_1	RELN ZAN ITGB3 MMRN1 LRP1 LRP6 TNR	9.21e-04	255	113	7	PS00022
Domain	Homeobox_CS	CDX4 EVX1 HOXB5 LMX1A DLX2 IRX2	9.42e-04	186	113	6	IPR017970
Domain	PH-BEACH_dom	NBEAL2 WDFY3	9.92e-04	8	113	2	IPR023362
Domain	-	NBEAL2 WDFY3	9.92e-04	8	113	2	2.30.29.40
Domain	PH_BEACH	NBEAL2 WDFY3	9.92e-04	8	113	2	PS51783
Domain	EGF	ZAN ITGB3 MMRN1 LRP1 LRP6	1.01e-03	126	113	5	PF00008
Domain	EGF-like_CS	RELN ZAN ITGB3 MMRN1 LRP1 LRP6 TNR	1.05e-03	261	113	7	IPR013032
Domain	EGF_2	RELN ZAN ITGB3 MMRN1 LRP1 LRP6 TNR	1.15e-03	265	113	7	PS01186
Domain	BEACH	NBEAL2 WDFY3	1.27e-03	9	113	2	PS50197
Domain	Beach	NBEAL2 WDFY3	1.27e-03	9	113	2	PF02138
Domain	-	NBEAL2 WDFY3	1.27e-03	9	113	2	1.10.1540.10
Domain	Beach	NBEAL2 WDFY3	1.27e-03	9	113	2	SM01026
Domain	BEACH_dom	NBEAL2 WDFY3	1.27e-03	9	113	2	IPR000409
Domain	-	CDX4 EVX1 ZEB2 HOXB5 LMX1A DLX2 IRX2	1.68e-03	283	113	7	1.10.10.60
Domain	-	DOC2A HECW1 CPNE5 SNRNP200 DOC2B	2.06e-03	148	113	5	2.60.40.150
Domain	ConA-like_dom	ZAN CMYA5 MMRN1 NBEAL2 WDFY3 MDGA1	2.16e-03	219	113	6	IPR013320
Domain	Homeobox_metazoa	CDX4 EVX1 HOXB5 DLX2	2.18e-03	90	113	4	IPR020479
Domain	Homeobox	CDX4 EVX1 HOXB5 LMX1A DLX2 IRX2	3.01e-03	234	113	6	PF00046
Domain	EGF	RELN ZAN MMRN1 LRP1 LRP6 TNR	3.07e-03	235	113	6	SM00181
Domain	EGF_3	RELN ZAN MMRN1 LRP1 LRP6 TNR	3.07e-03	235	113	6	PS50026
Domain	Ldl_recept_b	LRP1 LRP6	3.15e-03	14	113	2	PF00058
Domain	LDLRB	LRP1 LRP6	3.15e-03	14	113	2	PS51120
Domain	C2_dom	DOC2A HECW1 CPNE5 SNRNP200 DOC2B	3.22e-03	164	113	5	IPR000008
Domain	WHTH_DNA-bd_dom	FOXE1 FLI1 ADAR RFX4 SNRNP200 FOXI1	3.55e-03	242	113	6	IPR011991
Domain	Sialyl_trans	ST3GAL2 ST8SIA5	3.62e-03	15	113	2	IPR012163
Domain	LY	LRP1 LRP6	3.62e-03	15	113	2	SM00135
Domain	Pept_M10A_Zn_BS	MMP8 MMP10	3.62e-03	15	113	2	IPR021158
Domain	LDLR_classB_rpt	LRP1 LRP6	3.62e-03	15	113	2	IPR000033
Domain	WW_dom	HECW1 GALNT9 PLEKHA5	3.84e-03	52	113	3	IPR001202
Domain	Glycoside_hydrolase_SF	NAGA GLB1 CHID1	4.05e-03	53	113	3	IPR017853
Domain	Homeodomain-like	CDX4 EVX1 ZEB2 HOXB5 LMX1A DLX2 IRX2	4.08e-03	332	113	7	IPR009057
Domain	EGF-like_dom	RELN ZAN MMRN1 LRP1 LRP6 TNR	4.08e-03	249	113	6	IPR000742
Domain	MAM_1	ZAN MDGA1	4.12e-03	16	113	2	PS00740
Domain	Hemopexin_CS	MMP8 MMP10	4.65e-03	17	113	2	IPR018486
Domain	MAM	ZAN MDGA1	4.65e-03	17	113	2	SM00137
Domain	MAM	ZAN MDGA1	5.21e-03	18	113	2	PF00629
Domain	MAM_dom	ZAN MDGA1	5.21e-03	18	113	2	IPR000998
Domain	Pept_M10A_stromelysin-type	MMP8 MMP10	5.21e-03	18	113	2	IPR016293
Domain	MAM_2	ZAN MDGA1	5.21e-03	18	113	2	PS50060
Domain	EGF_extracell	RELN ITGB3 TNR	5.74e-03	60	113	3	IPR013111
Domain	EGF_2	RELN ITGB3 TNR	5.74e-03	60	113	3	PF07974
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	TET2 NRIP1 DCHS2 RELN ABCA2 WARS1 MYO6 FOLH1 ERC1 PSMD1 CCDC6 CMYA5 CPNE5 ZEB2 USP2 RNF220 NEUROD2 MTMR2 LRP1 WDFY3 SNRNP200	1.15e-09	1285	114	21	35914814
Pubmed	A census of human transcription factors: function, expression and evolution.	FOXE1 FLI1 CDX4 EVX1 RUNX3 RFX4 ZEB2 HOXB5 KMT2D NEUROD1 NEUROD2 LMX1A NFIL3 DLX2 SLC30A9 IRX2 FOXI1	7.30e-09	908	114	17	19274049
Pubmed	Impact of cytosine methylation on DNA binding specificities of human transcription factors.	FOXE1 FLI1 CDX4 EVX1 RUNX3 RFX4 HOXB5 NEUROD1 NEUROD2 LMX1A DLX2 FOXI1	2.47e-07	544	114	12	28473536
Pubmed	A family of human RNA-binding proteins related to the Drosophila Bruno translational regulator.	CELF6 CELF5 CELF3	6.81e-07	6	114	3	10893231
Pubmed	Presenilin 1 in migration and morphogenesis in the central nervous system.	RELN NEUROD1 LMX1A DLX2	1.31e-06	25	114	4	15163631
Pubmed	Long noncoding RNAs in mouse embryonic stem cell pluripotency and differentiation.	EVX1 HOXB5 DLX2	1.90e-06	8	114	3	18562676
Pubmed	Genome-wide association study of selenium concentrations.	DYNC2H1 CMYA5 CSMD1 IRX2	5.30e-06	35	114	4	25343990
Pubmed	A forward genetic screen in mice identifies mutants with abnormal cortical patterning.	RELN SEC24B LRP6	5.55e-06	11	114	3	23968836
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	TET2 NRIP1 ERC1 PSMD1 ZEB2 KMT2D MID1IP1 LRP1 PLEKHA5	1.02e-05	418	114	9	34709266
Pubmed	The proneural genes NEUROD1 and NEUROD2 are expressed during human trophoblast invasion.	NEUROD1 NEUROD2	1.07e-05	2	114	2	11900979
Pubmed	CBL mutations in myeloproliferative neoplasms are also found in the gene's proline-rich domain and in patients with the V617FJAK2.	CBLC CBL	1.07e-05	2	114	2	22315494
Pubmed	Doc2b synchronizes secretion from chromaffin cells by stimulating fast and inhibiting sustained release.	DOC2A DOC2B	1.07e-05	2	114	2	24133251
Pubmed	The bivariate NRIP1/ZEB2 RNA marker permits non-invasive presymptomatic screening of pre-eclampsia.	NRIP1 ZEB2	1.07e-05	2	114	2	33318568
Pubmed	Doc2: a novel brain protein having two repeated C2-like domains.	DOC2A DOC2B	1.07e-05	2	114	2	7826360
Pubmed	DOC2A and DOC2B are sensors for neuronal activity with unique calcium-dependent and kinetic properties.	DOC2A DOC2B	1.07e-05	2	114	2	16515538
Pubmed	Mutations of an E3 ubiquitin ligase c-Cbl but not TET2 mutations are pathogenic in juvenile myelomonocytic leukemia.	TET2 CBL	1.07e-05	2	114	2	20008299
Pubmed	Matrix metalloproteinases, tumor necrosis factor and multiple sclerosis: an overview.	MMP8 MMP10	1.07e-05	2	114	2	9042108
Pubmed	Low density lipoprotein receptor related protein 1 and 6 gene variants and ischaemic stroke risk.	LRP1 LRP6	1.07e-05	2	114	2	26031789
Pubmed	ADAR1-mediated regulation of melanoma invasion.	ADAR ITGB3	1.07e-05	2	114	2	29855470
Pubmed	DOC2 isoforms play dual roles in insulin secretion and insulin-stimulated glucose uptake.	DOC2A DOC2B	1.07e-05	2	114	2	25005332
Pubmed	Molecular cloning of an isoform of Doc2 having two C2-like domains.	DOC2A DOC2B	1.07e-05	2	114	2	8554557
Pubmed	Doc2b Ca2+ binding site mutants enhance synaptic release at rest at the expense of sustained synaptic strength.	DOC2A DOC2B	1.07e-05	2	114	2	31594980
Pubmed	Mutations of the TET2 and CBL genes: novel molecular markers in myeloid malignancies.	TET2 CBL	1.07e-05	2	114	2	20195608
Pubmed	Doc2b is a high-affinity Ca2+ sensor for spontaneous neurotransmitter release.	DOC2A DOC2B	1.07e-05	2	114	2	20150444
Pubmed	TET2 and CSMD1 genes affect SBP response to hydrochlorothiazide in never-treated essential hypertensives.	TET2 CSMD1	1.07e-05	2	114	2	25695618
Pubmed	NeuroD2 controls inhibitory circuit formation in the molecular layer of the cerebellum.	NEUROD1 NEUROD2	1.07e-05	2	114	2	30723302
Pubmed	The roles of MMP8/MMP10 polymorphisms in ischemic stroke susceptibility.	MMP8 MMP10	1.07e-05	2	114	2	36282475
Pubmed	Somatic mutations in KMT2D and TET2 associated with worse prognosis in Epstein-Barr virus-associated T or natural killer-cell lymphoproliferative disorders.	TET2 KMT2D	1.07e-05	2	114	2	31311407
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	TET2 FLI1 WARS1 NEK6 HDAC4 PABPC4 TM9SF3 ADAR ZEB2 KMT2D NFIL3 HNRNPA0 SNRNP200 PLIN3	1.57e-05	1103	114	14	34189442
Pubmed	BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.	MYO6 ERC1 PABPC4 TM9SF3 PSMD1 KIDINS220 SEC24B LRP6 PLEKHA5 SNRNP200 PLIN3	2.22e-05	708	114	11	39231216
Pubmed	A stream of cells migrating from the caudal telencephalon reveals a link between the amygdala and neocortex.	RELN NEUROD1 NEUROD2	2.26e-05	17	114	3	17694053
Pubmed	N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.	RELN ERC1 CCDC6 ITGB3 MMRN1 SEC24B PLEKHA5 PLIN3	2.59e-05	360	114	8	33111431
Pubmed	Combinatorial transcriptional control in blood stem/progenitor cells: genome-wide analysis of ten major transcriptional regulators.	TET2 FLI1 ITGB3	2.70e-05	18	114	3	20887958
Pubmed	[Replicative association analysis of genetic markers of cognitive traits with Alzheimer's disease in a Russian population].	NRIP1 CSMD1	3.19e-05	3	114	2	25845235
Pubmed	Excitatory and Inhibitory Neurons Utilize Different Ca2+ Sensors and Sources to Regulate Spontaneous Release.	DOC2A DOC2B	3.19e-05	3	114	2	29754754
Pubmed	C-Cbl binds the CSF-1 receptor at tyrosine 973, a novel phosphorylation site in the receptor's carboxy-terminus.	CBLC CBL	3.19e-05	3	114	2	11850825
Pubmed	Inactivation of c-Cbl or Cbl-b differentially affects signaling from the high affinity IgE receptor.	CBLC CBL	3.19e-05	3	114	2	15265912
Pubmed	Structure analyses reveal a regulated oligomerization mechanism of the PlexinD1/GIPC/myosin VI complex.	MYO6 PLXND1	3.19e-05	3	114	2	28537552
Pubmed	Doc2 is a Ca2+ sensor required for asynchronous neurotransmitter release.	DOC2A DOC2B	3.19e-05	3	114	2	22036572
Pubmed	Methylation of TET2, CBL and CEBPA in Ph-negative myeloproliferative neoplasms.	TET2 CBL	3.19e-05	3	114	2	20671051
Pubmed	DOC2 proteins in rat brain: complementary distribution and proposed function as vesicular adapter proteins in early stages of secretion.	DOC2A DOC2B	3.19e-05	3	114	2	9115738
Pubmed	Induction of pancreatic islet cell differentiation by the neurogenin-neuroD cascade.	NEUROD1 NEUROD2	3.19e-05	3	114	2	17924961
Pubmed	Loss of function Cbl-c mutations in solid tumors.	CBLC CBL	3.19e-05	3	114	2	31260484
Pubmed	Disease-linked mutations in Munc18-1 deplete synaptic Doc2.	DOC2A DOC2B	3.19e-05	3	114	2	38242640
Pubmed	Low density lipoprotein receptor-related protein 1 (LRP1) controls endocytosis and c-CBL-mediated ubiquitination of the platelet-derived growth factor receptor beta (PDGFR beta).	CBL LRP1	3.19e-05	3	114	2	15753096
Pubmed	RFX4 is an intrinsic factor for neuronal differentiation through induction of proneural genes POU3F2 and NEUROD1.	RFX4 NEUROD1	3.19e-05	3	114	2	38386071
Pubmed	Identification of a common viral integration region in Cas-Br-E murine leukemia virus-induced non-T-, non-B-cell lymphomas.	FLI1 CBL	3.19e-05	3	114	2	1845910
Pubmed	Doc2 Proteins Are Not Required for the Increased Spontaneous Release Rate in Synaptotagmin-1-Deficient Neurons.	DOC2A DOC2B	3.19e-05	3	114	2	32098902
Pubmed	Lhx9 and Lhx9alpha LIM-homeodomain factors: genomic structure, expression patterns, chromosomal localization, and phylogenetic analysis.	LMX1A DLX2	3.19e-05	3	114	2	10756098
Pubmed	Physical and functional interactions of Doc2 and Munc13 in Ca2+-dependent exocytotic machinery.	DOC2A DOC2B	3.19e-05	3	114	2	9195900
Pubmed	The mutational landscape of cutaneous T cell lymphoma and Sézary syndrome.	TET2 KMT2D	3.19e-05	3	114	2	26551667
Pubmed	NeuroD1 is an upstream regulator of NSCL1.	NEUROD1 NEUROD2	3.19e-05	3	114	2	22310718
Pubmed	Interaction of Doc2 with tctex-1, a light chain of cytoplasmic dynein. Implication in dynein-dependent vesicle transport.	DOC2A DOC2B	3.19e-05	3	114	2	9804756
Pubmed	NeuroD2 and neuroD3: distinct expression patterns and transcriptional activation potentials within the neuroD gene family.	NEUROD1 NEUROD2	3.19e-05	3	114	2	8816493
Pubmed	Interaction between two ubiquitin-protein isopeptide ligases of different classes, CBLC and AIP4/ITCH.	CBLC CBL	3.19e-05	3	114	2	12226085
Pubmed	A mouse model for hereditary thyroid dysgenesis and cleft palate.	FOXE1 TG	3.19e-05	3	114	2	9697704
Pubmed	An atlas of combinatorial transcriptional regulation in mouse and man.	FLI1 NRIP1 CDX4 LZTR1 HDAC4 RUNX3 RFX4 ZEB2 HOXB5 NEUROD1 LMX1A DLX2	3.22e-05	877	114	12	20211142
Pubmed	The AERO system: a 3D-like approach for recording gene expression patterns in the whole mouse embryo.	FLI1 HOXB5 LMX1A NFIL3 DLX2 IRX2	4.14e-05	191	114	6	24146773
Pubmed	Severe defects in dorsal thalamic development in low-density lipoprotein receptor-related protein-6 mutants.	RELN LRP6 DLX2	5.05e-05	22	114	3	15342729
Pubmed	Neuronal death resulting from targeted disruption of the Snf2 protein ATRX is mediated by p53.	RELN NEUROD1 NEUROD2	5.05e-05	22	114	3	19020049
Pubmed	Fezl regulates the differentiation and axon targeting of layer 5 subcortical projection neurons in cerebral cortex.	RELN PLXND1 NEUROD1 DLX2 DOC2B	6.17e-05	126	114	5	16284245
Pubmed	PAX8, TITF1, and FOXE1 gene expression patterns during human development: new insights into human thyroid development and thyroid dysgenesis-associated malformations.	FOXE1 TG	6.36e-05	4	114	2	15494458
Pubmed	Age-related loss of chromosome Y is associated with levels of sex hormone binding globulin and clonal hematopoiesis defined by TET2, TP53, and CBL mutations.	TET2 CBL	6.36e-05	4	114	2	37083525
Pubmed	Genetic variations in matrix metalloproteinases may be associated with increased risk of ulcerative colitis.	MMP8 MMP10	6.36e-05	4	114	2	21925226
Pubmed	The low density lipoprotein receptor-1, LRP1, interacts with the human frizzled-1 (HFz1) and down-regulates the canonical Wnt signaling pathway.	LRP1 LRP6	6.36e-05	4	114	2	14739301
Pubmed	Phosphorylation of synaptotagmin-1 controls a post-priming step in PKC-dependent presynaptic plasticity.	DOC2A DOC2B	6.36e-05	4	114	2	27091977
Pubmed	Platelet alpha IIb-beta 3 integrin engagement induces the tyrosine phosphorylation of Cbl and its association with phosphoinositide 3-kinase and Syk.	CBL ITGB3	6.36e-05	4	114	2	11042121
Pubmed	Overexpression of RUNX3 Represses RUNX1 to Drive Transformation of Myelodysplastic Syndrome.	TET2 RUNX3	6.36e-05	4	114	2	32341038
Pubmed	A cross-species genetic analysis identifies candidate genes for mouse anxiety and human bipolar disorder.	CMYA5 TNR	6.36e-05	4	114	2	26190982
Pubmed	Srsf2P95H/+ co-operates with loss of TET2 to promote myeloid bias and initiate a chronic myelomonocytic leukemia-like disease in mice.	TET2 CBL	6.36e-05	4	114	2	36271153
Pubmed	NeuroD factors regulate cell fate and neurite stratification in the developing retina.	NEUROD1 NEUROD2	6.36e-05	4	114	2	21593321
Pubmed	CXCL12-mediated HOXB5 overexpression facilitates Colorectal Cancer metastasis through transactivating CXCR4 and ITGB3.	ITGB3 HOXB5	6.36e-05	4	114	2	33456563
Pubmed	Characterization and expression of the mouse Hsc70 gene.	FLI1 CBL	6.36e-05	4	114	2	10095055
Pubmed	Enigma prevents Cbl-c-mediated ubiquitination and degradation of RETMEN2A.	CBLC CBL	6.36e-05	4	114	2	24466333
Pubmed	Activation of the precursor of human stromelysin 2 and its interactions with other matrix metalloproteinases.	MMP8 MMP10	6.36e-05	4	114	2	9578462
Pubmed	The Growth arrest specific 1 (Gas1) gene is transcriptionally regulated by NeuroD1 via two distal E-boxes.	NEUROD1 NEUROD2	6.36e-05	4	114	2	29395133
Pubmed	Regulation of neuroD2 expression in mouse brain.	NEUROD1 NEUROD2	6.36e-05	4	114	2	14697366
Pubmed	Single nucleotide polymorphism array lesions, TET2, DNMT3A, ASXL1 and CBL mutations are present in systemic mastocytosis.	TET2 CBL	6.36e-05	4	114	2	22905207
Pubmed	Non-EST-based prediction of novel alternatively spliced cassette exons with cell signaling function in Caenorhabditis elegans and human.	RUNX3 LRP1 WDFY3	6.60e-05	24	114	3	17452356
Pubmed	Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.	TET2 ABCA2 HDAC4 PLXND1 SNRNP200	7.16e-05	130	114	5	12421765
Pubmed	Patterning the dorsal telencephalon: a role for sonic hedgehog?	RELN LMX1A DLX2	7.48e-05	25	114	3	17959802
Pubmed	Dentate gyrus morphogenesis is regulated by β-catenin function in hem-derived fimbrial glia.	RELN NEUROD1 LMX1A	7.48e-05	25	114	3	36196585
Pubmed	A novel mode of tangential migration of cortical projection neurons.	RELN ZEB2	1.06e-04	5	114	2	16901480
Pubmed	Phagocytosis in macrophages lacking Cbl reveals an unsuspected role for Fc gamma receptor signaling and actin assembly in target binding.	CBLC CBL	1.06e-04	5	114	2	19380812
Pubmed	Molecular cloning of a highly conserved mouse and human integral membrane protein (Itm1) and genetic mapping to mouse chromosome 9.	FLI1 CBL	1.06e-04	5	114	2	8838310
Pubmed	Functional cooperation between c-Cbl and Src-like adaptor protein 2 in the negative regulation of T-cell receptor signaling.	CBLC CBL	1.06e-04	5	114	2	12024036
Pubmed	Cloning and chromosomal mapping of a gene isolated from thymic stromal cells encoding a new mouse type II membrane serine protease, epithin, containing four LDL receptor modules and two CUB domains.	FLI1 CBL	1.06e-04	5	114	2	10199918
Pubmed	Regulation of ubiquitin protein ligase activity in c-Cbl by phosphorylation-induced conformational change and constitutive activation by tyrosine to glutamate point mutations.	CBLC CBL	1.06e-04	5	114	2	15117950
Pubmed	Peroxisomal localization and circadian regulation of ubiquitin-specific protease 2.	USP2 NFIL3	1.06e-04	5	114	2	23133608
Pubmed	Doc2 supports spontaneous synaptic transmission by a Ca(2+)-independent mechanism.	DOC2A DOC2B	1.06e-04	5	114	2	21521611
Pubmed	Ablation of cDC2 development by triple mutations within the Zeb2 enhancer.	ZEB2 NFIL3	1.06e-04	5	114	2	35732734
Pubmed	TET2, ASXL1, IDH1, IDH2, and c-CBL genes in JAK2- and MPL-negative myeloproliferative neoplasms.	TET2 CBL	1.06e-04	5	114	2	21904853
Pubmed	Genetic deletion of sonic hedgehog causes hemiagenesis and ectopic development of the thyroid in mouse.	FOXE1 TG	1.06e-04	5	114	2	15111333
Pubmed	c-Cbl and Cbl-b act redundantly to protect osteoclasts from apoptosis and to displace HDAC6 from beta-tubulin, stabilizing microtubules and podosomes.	CBLC CBL	1.06e-04	5	114	2	19641021
Pubmed	Doc2B acts as a calcium sensor for vesicle priming requiring synaptotagmin-1, Munc13-2 and SNAREs.	DOC2A DOC2B	1.06e-04	5	114	2	29274147
Pubmed	Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function.	TET2 HDAC4 LRP1	1.31e-04	30	114	3	21946350
Pubmed	The transcriptional repressor RP58 is crucial for cell-division patterning and neuronal survival in the developing cortex.	RELN NEUROD1 DLX2	1.31e-04	30	114	3	19409883
Pubmed	The CELF family of RNA binding proteins is implicated in cell-specific and developmentally regulated alternative splicing.	CELF5 CELF3	1.58e-04	6	114	2	11158314
Pubmed	An Mtb-Human Protein-Protein Interaction Map Identifies a Switch between Host Antiviral and Antibacterial Responses.	CBLC CBL	1.58e-04	6	114	2	30118682
Pubmed	Mice deficient for RNA-binding protein brunol1 show reduction of spermatogenesis but are fertile.	CELF6 CELF3	1.58e-04	6	114	2	17393433
GeneFamily	WD repeat domain containing\|BEACH domain containing	NBEAL2 WDFY3	7.52e-04	9	84	2	1230
GeneFamily	Synaptotagmin like tandem C2 proteins	DOC2A DOC2B	9.37e-04	10	84	2	822
GeneFamily	Low density lipoprotein receptors	LRP1 LRP6	1.61e-03	13	84	2	634
GeneFamily	HOXL subclass homeoboxes	CDX4 EVX1 HOXB5	1.81e-03	52	84	3	518
Coexpression	BENPORATH_EED_TARGETS	FOXE1 TET2 FLI1 DCHS2 RELN EVX1 PLXND1 PTGER4 ZEB2 NEUROD1 NEUROD2 DLX2 ST8SIA5 CSMD1 MDGA1 EPHX3	1.12e-05	1059	112	16	M7617
Coexpression	GSE15930_NAIVE_VS_48H_IN_VITRO_STIM_IFNAB_CD8_TCELL_UP	NRIP1 HLA-DOA NAGA ITGB3 CLDN6 USP2 PLEKHA5	2.34e-05	198	112	7	M3601
Coexpression	GSE29949_CD8_NEG_DC_SPLEEN_VS_CD8_POS_DC_SPLEEN_UP	RELN PLXND1 NEUROD2 NFIL3 LRP1 TNR PLIN3	2.42e-05	199	112	7	M8390
Coexpression	GSE19888_ADENOSINE_A3R_INH_VS_ACT_WITH_INHIBITOR_PRETREATMENT_IN_MAST_CELL_DN	HDAC4 TMEM151B PABPC4 PLPP7 ZEB2 TSFM MDGA1	2.50e-05	200	112	7	M7323
Coexpression	GSE7460_TREG_VS_TCONV_ACT_WITH_TGFB_DN	HDAC4 HLA-DOA PGGT1B ST8SIA5 CHID1 PLIN3 TECPR1	2.50e-05	200	112	7	M5693
Coexpression	MIKKELSEN_MEF_HCP_WITH_H3K27ME3	DOC2A RELN CBLC RFX4 CLDN6 NEUROD1 NEUROD2 LMX1A CSMD1 EPHX3 DOC2B	4.69e-05	591	112	11	M2019
Coexpression	ZHONG_PFC_C3_MICROGLIA	CELF5 ABCA2 TMEM151B RNF220 CELF3 LRP6 DLG3 DLX2 CSMD1 MDGA1	4.74e-05	488	112	10	M39104
Coexpression	MIKKELSEN_MEF_HCP_WITH_H3K27ME3	DOC2A RELN CBLC RFX4 CLDN6 NEUROD1 NEUROD2 LMX1A CSMD1 EPHX3 DOC2B	5.45e-05	601	112	11	MM866
CoexpressionAtlas	ratio_EmbryoidBody_vs_StemCell_top-relative-expression-ranked_500	FLI1 RELN SLC39A2 RFX4 ITGB3 ZEB2 MMRN1 HOXB5 LMX1A CELF3 DLX2 MDGA1	1.06e-05	498	110	12	PCBC_ratio_EB_vs_SC_500
ToppCell	COVID-19_Mild\|World / Disease condition and Cell class	TET2 NRIP1 WARS1 RUNX3 ADAR ZEB2 LRP1 DSE	4.51e-08	198	114	8	61ceb2245b6cb58e308b999a61d218c89dbc615e
ToppCell	Neuroendocrine-neuroendo-1\|World / Class top	CELF6 CLDN6 TG HOXB5 CELF3 ST8SIA5 DOC2B	4.19e-07	180	114	7	50fdd182a083380899b5943cb5f55ffd77e2a7d4
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN ZAN HECW1 MYO7B FOLH1 GMNC CSMD1	4.86e-07	184	114	7	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN ZAN HECW1 MYO7B FOLH1 GMNC CSMD1	4.86e-07	184	114	7	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN ZAN HECW1 MYO7B FOLH1 GMNC CSMD1	4.86e-07	184	114	7	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	COPD-Myeloid-Macrophage\|World / Disease state, Lineage and Cell class	TET2 RAB31 HLA-DOA PABPC4 IRAK2 ZEB2 CSMD1	6.93e-07	194	114	7	7d682408e9a6239a4e47befc9376e760cc3d133a
ToppCell	severe-HLA-DR+_CD83+_Monocyte\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	TET2 RAB31 PLXND1 ZEB2 LRP1 WDFY3 DSE	7.95e-07	198	114	7	d5e525d2f2226d06a3fb985ce3a33555ff4b2e7b
ToppCell	severe-HLA-DR-_S100A+_Monocyte\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	NRIP1 RAB31 OTUD1 NFIL3 LRP1 PLIN3 DSE	8.50e-07	200	114	7	db7046741706376682d164c385c4701aebefc2e6
ToppCell	mild-Classical_Monocyte\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	TET2 RAB31 WARS1 ZEB2 NFIL3 LRP1 DSE	8.50e-07	200	114	7	c8b80d4e7f70c66cbbdd0665821bcd5db69c7d35
ToppCell	severe-Classical_Monocyte\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	RAB31 OTUD1 ZEB2 NFIL3 LRP1 PLIN3 DSE	8.50e-07	200	114	7	f46689940fdea500ce2457eec412dd2c46705819
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW09-Neuronal-Neurons\|GW09 / Sample Type, Dataset, Time_group, and Cell type.	CELF5 MYO6 ZEB2 NEUROD1 NEUROD2 KIDINS220 CELF3	8.50e-07	200	114	7	ddac952ad1d46021c2d17d816de9bc31730a0941
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-2m-Neuronal-Neuron\|2m / Sample Type, Dataset, Time_group, and Cell type.	MYO6 HOXB5 NEUROD1 NEUROD2 CELF3 HNRNPA0 ST8SIA5	8.50e-07	200	114	7	a581f1704a87b0390e1e2ff85053367d85247755
ToppCell	LPS-IL1RA+antiTNF-Endothelial-Epi-like-Gen_Cap\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	HECW1 ST3GAL2 TG MMRN1 LRP1 CHID1	1.79e-06	142	114	6	d52da766e031f7409eb5a7a9fa88f48e14a79d8b
ToppCell	LPS-IL1RA+antiTNF-Endothelial-Epi-like\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	HECW1 ST3GAL2 TG MMRN1 LRP1 CHID1	1.79e-06	142	114	6	a05b320cf182b2aaf18df7c40045dc65b659bf20
ToppCell	facs-Brain_Non-Myeloid-Hippocampus_-18m-Neuronal-neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HECW1 SLC35F4 NEUROD2 SLC12A1 GALNT9 DOC2B	4.58e-06	167	114	6	3dfec2fcc36caa6e394efae5e540a6fa28759977
ToppCell	facs-Brain_Non-Myeloid-Hippocampus_-18m-Neuronal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HECW1 SLC35F4 NEUROD2 SLC12A1 GALNT9 DOC2B	4.58e-06	167	114	6	95b3b5ba3414729f0460a26a0deca48de0cbe33e
ToppCell	facs-Brain_Non-Myeloid-Hippocampus_-18m-Neuronal-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HECW1 SLC35F4 NEUROD2 SLC12A1 GALNT9 DOC2B	4.58e-06	167	114	6	9480739587d51e67a281778b9bddd7b5ffc3ad92
ToppCell	5'-GW_trimst-2-SmallIntestine-Hematopoietic-Myeloid-Megakaryocyte\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LANCL3 CPA3 CPNE5 ITGB3 MMRN1 NBEAL2	5.99e-06	175	114	6	b85279b9efd72d7074c4226d50ce139a38c0e1c1
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-Mono-Mono_anti-infl-B\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	PLXND1 NFIL3 LRP1 MMP8 LILRB5 DSE	6.39e-06	177	114	6	382f0d6bbff01e84b0c7840e74ac865864e6da89
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal-neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HECW1 TMEM151B NEUROD2 LMX1A ST8SIA5 MDGA1	7.03e-06	180	114	6	3d54cc767e25d91ed2203d8a03e5bf5e15f21699
ToppCell	10x_3'_v2v3-Neoplastic-Stem-like-NPC-like-NPC-like_neural-A\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CELF5 CLDN6 SLC35F4 CELF3 DLX2 ST8SIA5	7.73e-06	183	114	6	af14da45267261e775dd6dab7a4c359b181e46f1
ToppCell	3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage-Monocyte-derived_macrophage_L.1.2.5.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TET2 OTUD1 ZEB2 NFIL3 LILRB5 DSE	7.97e-06	184	114	6	d1ea2b60fb1ca1a0b809d131310c43903a9e84ce
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Neuronal-nan\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DOC2A RELN ITGB3 MMRN1 GJC3 CSMD1	7.97e-06	184	114	6	e33bb572af9dfd11127105f1ac99bc958a7cafbb
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal-interneuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN NEUROD1 NEUROD2 GALNT9 ST8SIA5 IRX2	8.74e-06	187	114	6	1b2fdbfb1ce3f19795dfc4b1da5a94f4b057ec41
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Neuronal-neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM151B NEUROD1 NEUROD2 LMX1A ST8SIA5 MDGA1	9.01e-06	188	114	6	1efbc99bcd6542e5d9fa91edb7c4295167914786
ToppCell	control-Myeloid-CD14_Monocytes_2\|control / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	WARS1 OTUD1 NAGA ZEB2 LRP1 DSE	9.57e-06	190	114	6	47513757e0059e8370e49672a577f25ca842e98c
ToppCell	10x5'-GI_small-bowel-Myeloid_Dendritic-migDC\|GI_small-bowel / Manually curated celltypes from each tissue	RAB31 WARS1 NEK6 HLA-DOA CBLC NPFFR1	9.57e-06	190	114	6	e9b2c201d07f0cb87fa60005251c9e1663e246ed
ToppCell	PCW_10-12-Endothelial-Endothelial_mature-endo_venous_(13)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	FLI1 PLXND1 CPNE5 MMRN1 MMP10 DOC2B	1.08e-05	194	114	6	efd5efed060edb7f24d59600981bb60ec28ac2ef
ToppCell	Control-Myeloid-Macrophage\|World / Disease state, Lineage and Cell class	TET2 RAB31 OTUD1 IRAK2 ZEB2 DSE	1.08e-05	194	114	6	c35bf04d5e7450cb6679a036fcabb1b28f409f29
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FLI1 RAB31 PLXND1 ZEB2 LRP1 LILRB5	1.08e-05	194	114	6	1dce6d4b6ac41f80677e3e4c335a4f383bd76f85
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_anti-infl-E\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	TET2 OTUD1 PLXND1 MFSD12 NFIL3 DSE	1.08e-05	194	114	6	449ce4167d64c170d914e0250f739eabedcf915d
ToppCell	saliva-Severe-critical_progression_d28-40-Myeloid-Macrophage-macrophage,_alveolar\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	NRIP1 WARS1 OTUD1 PABPC4 PLXND1 LRP1	1.14e-05	196	114	6	7ce416e1809bfbb39553c28c20125790100a938d
ToppCell	saliva-Severe-critical_progression_d28-40-Myeloid-Macrophage\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	NRIP1 WARS1 OTUD1 PABPC4 PLXND1 LRP1	1.14e-05	196	114	6	292da8a0c052917a2f68afee9068b5b8e1544b13
ToppCell	10x_3'_v2v3-Neoplastic-Stem-like-NPC-like-NPC-like_neural-F\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CELF5 EVX1 NEUROD1 NEUROD2 CELF3 DLX2	1.18e-05	197	114	6	b4554353c56e220bae31ee3c8aa222674dd0b18c
ToppCell	control-Myeloid-Non-resident_Macrophage\|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	TET2 RAB31 NAGA NFIL3 LRP1 DSE	1.18e-05	197	114	6	df2fe36cb96e2565a9d21c24cb4e451e8befd4be
ToppCell	3'-GW_trimst-1-SmallIntestine-Neuronal-neurons_B\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CELF5 TMEM151B HOXB5 CELF3 DLX2 DOC2B	1.18e-05	197	114	6	8951787ed1f7ac1772a6ef0ba2dd44c51fd3c47b
ToppCell	saliva-Severe-critical_progression_d12-22_no-steroids\|saliva / Compartment, severity and other cell annotations on 10x 3' data (130k)	NEK6 PLXND1 PTGER4 ZEB2 LRP1 DSE	1.18e-05	197	114	6	c747d05bb032abf8dad46ff6f4d1951bbe64b3b4
ToppCell	3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-lung_macrophage-Interstitial_macrophage_perivascular\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	RAB31 OTUD1 ZEB2 NFIL3 LILRB5 DSE	1.21e-05	198	114	6	5cd5cc67d7bb294582b5e9115cbddfd88aeb5220
ToppCell	3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-lung_macrophage\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	RAB31 OTUD1 ZEB2 NFIL3 LILRB5 DSE	1.21e-05	198	114	6	311d3ef860d0d883130326fd4601ee9ad89029ff
ToppCell	severe-HLA-DR+_CD83+_Monocyte\|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	TET2 PLXND1 ZEB2 LRP1 WDFY3 DSE	1.21e-05	198	114	6	a77f3440d7fb6a50066abc7e9ad59e83798ef13d
ToppCell	3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-lung_macrophage-Interstitial_macrophage_perivascular-Interstitial_macrophage_perivascular_L.1.2.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	RAB31 OTUD1 ZEB2 NFIL3 LILRB5 DSE	1.21e-05	198	114	6	fa06b60e7ec58754bb622fd439613d63afd2205f
ToppCell	facs-Brain_Non-Myeloid-Striatum-3m-Macroglial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA2 RAB31 MYO6 ZEB2 MID1IP1 GJC3	1.21e-05	198	114	6	27f0654fb0857e93f030e1a4b1c307b31576bbcd
ToppCell	mild-HLA-DR-_S100A+_Monocyte\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	RAB31 OTUD1 NFIL3 LRP1 WDFY3 DSE	1.25e-05	199	114	6	d0d286eafe935f9b3aaba5b783e8911251121b4a
ToppCell	COPD-Myeloid-Macrophage\|Myeloid / Disease state, Lineage and Cell class	TET2 RAB31 PABPC4 IRAK2 CSMD1 LILRB5	1.25e-05	199	114	6	1cf1b2d6debf9e3389f1829dcaa2857e9533a080
ToppCell	Tracheal-NucSeq-Immune_Myeloid-Macrophage_other-Macrophage_intermediate\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FLI1 RAB31 OTUD1 PLXND1 ZEB2 LILRB5	1.25e-05	199	114	6	54167894a16e975d0541cbe3e515bcfa183044f6
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	HECW1 CMYA5 LRP1 LRP6 CSMD1 TNR	1.25e-05	199	114	6	19a97e27a4758e794ce7246d295e112b47931a48
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW09-Neuronal\|GW09 / Sample Type, Dataset, Time_group, and Cell type.	CELF5 ZEB2 NEUROD1 NEUROD2 KIDINS220 CELF3	1.28e-05	200	114	6	e9eb348a66011d8aace4331f84690ae27cb0d061
ToppCell	Influenza\|World / Disease, condition lineage and cell class	RAB31 OTUD1 ZEB2 NFIL3 NBEAL2 PLIN3	1.28e-05	200	114	6	df996c35907a1c9194b9e2ca30e81f520ca067f0
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW09-Neuronal\|GW09 / Sample Type, Dataset, Time_group, and Cell type.	CELF5 MYO6 ZEB2 NEUROD1 NEUROD2 KIDINS220	1.28e-05	200	114	6	09fd3cb31bcc02444f1045f01fe39bce09359d35
ToppCell	Severe-Myeloid-Macrophages-FCN1-SPP1+\|Severe / Condition, Lineage, Cell class and cell subclass	RAB31 HLA-DOA PLXND1 MFSD12 LRP1 LILRB5	1.28e-05	200	114	6	b8cd209b810312793465b28bb2a6cbe5d94da91f
ToppCell	severe-CD163+_Monocytes_(Sample_ID1_d7)\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	RAB31 OTUD1 LRP1 WDFY3 PLIN3 DSE	1.28e-05	200	114	6	a3f22826f3d8f917ff0594bdadd93b60763bcaa2
ToppCell	COVID_non-vent\|World / Disease condition, Lineage, Cell class and subclass	RAB31 WARS1 OTUD1 ADAR NFIL3 LRP1	1.28e-05	200	114	6	accef1050963dc91e189ac3d38228f15bf57e06e
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Myeloid-Monocytic-Nonclassical_Monocyte-Mono_c4-CD14-CD16\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	RAB31 IRAK2 CLDN6 USP2 WDFY3	3.96e-05	148	114	5	fd0d8386b94adb1bdc993fbb44d2d87852bfd7f0
ToppCell	Thalamus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)\|Thalamus / BrainAtlas - Mouse McCarroll V32	LANCL3 CPNE5 SLC35F4 DLX2 DOC2B	3.96e-05	148	114	5	afebb64365c94b9476494bffe7c364677f19c8cf
ToppCell	Thalamus-Neuronal-Inhibitory\|Thalamus / BrainAtlas - Mouse McCarroll V32	LANCL3 CPNE5 SLC35F4 DLX2 DOC2B	3.96e-05	148	114	5	5f82e5ecacfd223020b8ee975c17d68c1fe6db38
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-DC-cDC2-B\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	TET2 PTGER4 NPFFR1 TG NFIL3	5.09e-05	156	114	5	0f54d62c0fc08bbdd5ac743b2d5d748c3d1e6ef9
ToppCell	Thalamus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)\|Thalamus / BrainAtlas - Mouse McCarroll V32	CELF6 NEUROD1 NEUROD2 MDGA1 IRX2	5.91e-05	161	114	5	0605134a342d74ae81f33700d6ddfcd6e03aeb7b
ToppCell	5'-Adult-SmallIntestine-Epithelial-neuro-epithelial-EECs\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NEUROD1 NEUROD2 CELF3 ST8SIA5 MMP10	6.09e-05	162	114	5	478cf560ef33c5c324142c76417447d4a571a2c9
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_119\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CELF6 SLC35F4 LRP1 MDGA1 TNR	6.64e-05	165	114	5	cca3ba9d7d30404e3e683b8cfd500c348a4974b9
ToppCell	severe-unassigned\|severe / disease stage, cell group and cell class	ST3GAL2 TSFM SEPSECS PLEKHA5 WDFY3	6.64e-05	165	114	5	f9ddd547992fec065d539a1d0305acba8fc7d79c
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Neuronal-Granular_Neuron_CB_Gabra6\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM151B NEUROD1 NEUROD2 LMX1A MDGA1	6.83e-05	166	114	5	ec7bd549bda5f18aca8aebce5ba479a81abbbeda
ToppCell	Posterior_cortex-Neuronal-Inhibitory\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	CELF6 LANCL3 RELN ZEB2 DLX2	7.03e-05	167	114	5	9a84f45345c75f2c8ff38a04245aadee2a26a240
ToppCell	droplet-Fat-Bat-18m\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CCNJL PLPP7 CCDC6 CSMD1 EPHX3	7.64e-05	170	114	5	c720d81bc29a8fd1f1249c6af408471d561f1d5d
ToppCell	droplet-Fat-Bat\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CCNJL PLPP7 CCDC6 CSMD1 EPHX3	7.64e-05	170	114	5	c4ecdfc2b4710da0a5fbb20e9df02536023badb1
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM151B NEUROD1 NEUROD2 GALNT9 ST8SIA5	7.86e-05	171	114	5	99176a932569fa1c7e1c01009684f5a65244b96e
ToppCell	COVID-19-Heart-T_cell\|COVID-19 / Disease (COVID-19 only), tissue and cell type	RELN RUNX3 RFX4 CSMD1 TNR	7.86e-05	171	114	5	b2e753e811a7639956994609f73efcdb62d04f82
ToppCell	facs-BAT-Fat-3m-Myeloid-nan\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RAB31 ZEB2 NFIL3 GALNT9 LRP1	8.08e-05	172	114	5	5f18c3f8eb8b7928901eede44c9b84b3c5efa1a9
ToppCell	E18.5-Epithelial-Epithelial_Airway-Neurosecretory-PNEC-PNEC_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CELF6 SLC35F4 CELF3 DLX2 DOC2B	8.53e-05	174	114	5	742c73c9e090848b464323cb17579b86658c6792
ToppCell	E18.5-Epithelial-Epithelial_Airway-Neurosecretory-PNEC\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CELF6 SLC35F4 CELF3 DLX2 DOC2B	8.53e-05	174	114	5	7fed9722e64c60843092f2ba71256e3043011ef6
ToppCell	facs-Marrow-Granulocytes-3m-Myeloid-monocyte_+_promonocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLXND1 ZEB2 GALNT9 LRP1 DSE	8.76e-05	175	114	5	69b59ec58e64644deb7e07f31ef495ef4a6f6276
ToppCell	facs-Marrow-Granulocytes-3m-Myeloid-promonocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLXND1 ZEB2 GALNT9 LRP1 DSE	8.76e-05	175	114	5	4f7498b5a0ed52c348a5f94bcd41d830ba7954ea
ToppCell	Thalamus-Neuronal-Excitatory\|Thalamus / BrainAtlas - Mouse McCarroll V32	CELF5 HECW1 NEUROD1 CELF3 TECPR1	9.00e-05	176	114	5	d2bbf13d21fb7582d7e5f90cd61a4ebe1cfccd66
ToppCell	PND14-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet-Megakaryocyte/Platelet_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TMEM151B CBL ITGB3 MMRN1 NBEAL2	9.49e-05	178	114	5	63f5880a5b514e20ef2c07a6a9cb8df34e6cede5
ToppCell	PND14-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TMEM151B CBL ITGB3 MMRN1 NBEAL2	9.49e-05	178	114	5	82c84f8b8a7e6a3d3be3351b348a37143279c100
ToppCell	Adult-Endothelial-endothelial_cell_of_lymph_vessel-D231\|Adult / Lineage, Cell type, age group and donor	DCHS2 RELN CPNE5 MMRN1 DOC2B	9.49e-05	178	114	5	c80ca7a2d3f976089a5e71d0cd9ba9a1c0bd2815
ToppCell	PND14-Immune-Immune_Myeloid-Megakaryocyte/Platelet\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TMEM151B CBL ITGB3 MMRN1 NBEAL2	9.49e-05	178	114	5	cb91558469ae0748106fb0b6d702edb0ff21a884
ToppCell	droplet-Lung-18m-Hematologic-myeloid-classical_monocyte\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ZEB2 NFIL3 GALNT9 LRP1 MMP8	9.75e-05	179	114	5	66afd54428e6dcadc3e341faecfde42be4fb5905
ToppCell	5'-GW_trimst-2-LargeIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	EVX1 NEUROD1 LMX1A CELF3 ST8SIA5	9.75e-05	179	114	5	d70791d2a0db35a6b013fa7ed2f9f39364581eff
ToppCell	LPS_only-Myeloid-Neutrophils\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	RAB31 IRAK2 ZEB2 MID1IP1 MMP8	9.75e-05	179	114	5	d0a03e498afcfeb657037889685ecd77bed07e6c
ToppCell	droplet-Lung-18m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l2\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ZEB2 NFIL3 GALNT9 LRP1 MMP8	9.75e-05	179	114	5	fa58fa0901eadb170e3d2facb2a3d8c5e624329a
ToppCell	LPS_only-Myeloid-Neutrophils-Neutrophils\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	RAB31 IRAK2 ZEB2 MID1IP1 MMP8	9.75e-05	179	114	5	d034651a5a355a58f5e15db627869f4feebdfe35
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal-Granular_Neuron_CB_Gabra6\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM151B NEUROD1 NEUROD2 LMX1A MDGA1	1.00e-04	180	114	5	d76349ecef7c5878bf215e946f032264161eb61b
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN HLA-DOA RUNX3 NEUROD1 NEUROD2	1.00e-04	180	114	5	6ac62bf1251978c8c12e715f7b73144fca619794
ToppCell	Fetal_29-31_weeks-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	FLI1 WARS1 IRAK2 PLXND1 DOC2B	1.00e-04	180	114	5	d8ef44710a77ad0fc03243428e5e1dc4d41200cb
ToppCell	5'-Adult-Appendix-Endothelial-lymphatic_endothelial-LEC6_(ADAMTS4+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RELN WARS1 IRAK2 ITGB3 MMRN1	1.05e-04	182	114	5	fd786c88826ad3d5cc5c3d80f8e392d6be1b5267
ToppCell	LPS_only-Myeloid\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	RAB31 IRAK2 ZEB2 MID1IP1 MMP8	1.05e-04	182	114	5	666ac86ee5f6fa9241ae8d80340743707e54b278
ToppCell	5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(nasal)-Club_(nasal)_L.0.2.3.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	WARS1 CCDC6 CMYA5 ZBED6 DOC2B	1.08e-04	183	114	5	2dde2fb48e7d31271c2f6b1dd74b2ab0b2cb520c
ToppCell	3'-GW_trimst-1-LargeIntestine-Neuronal-Glial_immature-Glia_1_(DHH+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RELN ZEB2 DLX2 ST8SIA5 GJC3	1.08e-04	183	114	5	547b1fb9f9940cfc8d6e351d96acc0da44def57e
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW23-Neuronal\|GW23 / Sample Type, Dataset, Time_group, and Cell type.	ZEB2 NEUROD1 KIDINS220 DLX2	1.09e-04	96	114	4	56e993d37b7958abe56682422536045550e29b41
ToppCell	COPD-Myeloid-cMonocyte\|World / Disease state, Lineage and Cell class	TET2 RAB31 WARS1 ZEB2 CSMD1	1.11e-04	184	114	5	ceec41ed5636032aaf7716d1203816ea58bd39bd
ToppCell	5'-Adult-Appendix-Endothelial-lymphatic_endothelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RELN WARS1 IRAK2 ITGB3 MMRN1	1.11e-04	184	114	5	453295362888c9a59d0e73c7a5b15914c50ff591
ToppCell	3'-GW_trimst-2-LargeIntestine-Endothelial-lymphatic_endothelial-LEC4_(STAB2+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FLI1 RELN WARS1 PLXND1 MMRN1	1.11e-04	184	114	5	3b0389c3a5a16697de860e98ebc48ed39ede646f
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM151B NEUROD1 NEUROD2 LMX1A ST8SIA5	1.11e-04	184	114	5	7d9bcdaff8cbea4c50ab7db0f8e01f6bbd0ef593
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_hypoxia/MES-E\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	NRIP1 ITGB3 MFSD12 NFIL3 DSE	1.11e-04	184	114	5	e343dd7777a29048e3f12a939f7f782b8b7b4fea
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM151B NEUROD1 NEUROD2 LMX1A MDGA1	1.14e-04	185	114	5	cdd75abdaa1ecedfd2e636203b83a6ac1782f0c3
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Neuronal-neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM151B NEUROD1 NEUROD2 LMX1A MDGA1	1.14e-04	185	114	5	70de48988c1f8e0809afc8092b663aa439d8e528
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Myeloid-Dendritic\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	RAB31 WARS1 CCDC6 PTGER4 DSE	1.14e-04	185	114	5	405bd4ba7ca7f7b625c49f1313ff946509e17c13
ToppCell	facs-Brain_Non-Myeloid-Cerebellum\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM151B NEUROD1 NEUROD2 LMX1A MDGA1	1.14e-04	185	114	5	c083a4974590b9ed3ecafedd3e9cdebc5047fe39
ToppCell	PBMC-Mild-cDC_8\|Mild / Compartment, Disease Groups and Clusters	OTUD1 CPNE5 PTGER4 MID1IP1 HNRNPA0	1.14e-04	185	114	5	891b39c20fe9858fbba90d9ef7a253f1a0870211
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Myeloid-Dendritic-conventional_dendritic_cell\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	RAB31 WARS1 CCDC6 PTGER4 DSE	1.14e-04	185	114	5	2aa5e9f6f167d27317a01d22392b59512333fa64
Disease	Papillary thyroid carcinoma	FOXE1 WARS1 ERC1 CCDC6 ZEB2	1.88e-05	86	111	5	C0238463
Disease	Noonan syndrome (implicated_via_orthology)	LZTR1 CBL	8.37e-05	4	111	2	DOID:3490 (implicated_via_orthology)
Disease	aortic aneurysm (is_marker_for)	HDAC4 PTGER4	8.37e-05	4	111	2	DOID:3627 (is_marker_for)
Disease	joint damage measurement	CCNJL TG SEPSECS CSMD1	1.28e-04	68	111	4	EFO_0005413
Disease	blood platelet disease (is_implicated_in)	FLI1 ITGB3	1.39e-04	5	111	2	DOID:2218 (is_implicated_in)
Disease	corpus callosum mid-anterior volume measurement	TG GMNC SEPSECS	1.42e-04	27	111	3	EFO_0010297
Disease	Contact Dermatitis	HDAC4 GLB1 MMP8 MMP10	1.52e-04	71	111	4	C0011616
Disease	Contact hypersensitivity	HDAC4 GLB1 MMP8 MMP10	1.52e-04	71	111	4	C0162351
Disease	stomach cancer (is_marker_for)	TET2 LZTR1 RUNX3 ADAR KMT2D	2.05e-04	142	111	5	DOID:10534 (is_marker_for)
Disease	stromelysin-2 measurement	MMP8 MMP10	2.08e-04	6	111	2	EFO_0802095
Disease	matrix metalloproteinase 10 measurement	MMP8 MMP10	2.91e-04	7	111	2	EFO_0010589
Disease	heart rate variability measurement	CPNE5 RNF220 HNRNPA0	3.67e-04	37	111	3	EFO_0008003
Disease	multiple sclerosis	TET2 FLI1 RUNX3 TSFM TG SEPSECS GARIN3 GLB1 CSMD1	4.18e-04	594	111	9	MONDO_0005301
Disease	Unipolar Depression	RELN CMYA5 TG LRP1 DLG3 MMP8	4.53e-04	259	111	6	C0041696
Disease	eosinophil count	TET2 FLI1 NRIP1 NEK6 HLA-DOA IRAK2 CBLC CPA3 RUNX3 ITGB3 TG SEPSECS GLB1 NFIL3 SNRNP200	4.62e-04	1488	111	15	EFO_0004842
Disease	Schizophrenia	NRIP1 RELN HDAC4 FOLH1 CMYA5 ITGB3 LMX1A LRP1 DLG3 CSMD1 MDGA1	5.05e-04	883	111	11	C0036341
Disease	autoimmune disease	NEK6 HLA-DOA ITGB3 TG PLIN3	5.08e-04	173	111	5	EFO_0005140
Disease	Vitiligo	FLI1 NEK6 TG PLIN3	5.85e-04	101	111	4	EFO_0004208
Disease	glucose measurement	TET2 WIPI1 WARS1 ZAN FOLH1 NEUROD1 GALNT9	6.00e-04	380	111	7	EFO_0004468
Disease	thyroid gland papillary carcinoma (is_implicated_in)	FOXE1 KMT2D	6.19e-04	10	111	2	DOID:3969 (is_implicated_in)
Disease	WNT1-inducible-signaling pathway protein 1 measurement	TG SEPSECS	6.19e-04	10	111	2	EFO_0008321
Disease	Ankylosing spondylitis	RUNX3 PTGER4	7.54e-04	11	111	2	C0038013
Disease	dodecanedioate measurement	PGGT1B MDGA1	9.03e-04	12	111	2	EFO_0021054
Disease	sleep apnea measurement	HDAC4 HECW1 LMX1A OR10AD1	9.82e-04	116	111	4	EFO_0007817
Disease	cortical thickness	CELF5 PRR23A RELN CPA3 PLXND1 RFX4 TG GMNC SEPSECS LMX1A MTMR2 LRP1	9.97e-04	1113	111	12	EFO_0004840
Disease	matrix metalloproteinase measurement	DYNC2H1 LILRB5	1.06e-03	13	111	2	EFO_0004744
Disease	Congenital Hypothyroidism	FOXE1 TG	1.06e-03	13	111	2	C0010308
Disease	triacylglycerol 52:2 measurement	TG SEPSECS CSMD1	1.18e-03	55	111	3	EFO_0010414
Disease	congenital hypothyroidism (implicated_via_orthology)	FOXE1 TG	1.24e-03	14	111	2	DOID:0050328 (implicated_via_orthology)
Disease	Graves' disease (is_marker_for)	ITGB3 TG	1.43e-03	15	111	2	DOID:12361 (is_marker_for)
Disease	RASopathy	LZTR1 CBL	1.43e-03	15	111	2	cv:C5555857
Disease	Familial Nonmedullary Thyroid Cancer	WARS1 CCDC6 ZEB2	1.59e-03	61	111	3	C3501844
Disease	Nonmedullary Thyroid Carcinoma	WARS1 CCDC6 ZEB2	1.59e-03	61	111	3	C3501843
Disease	cortical surface area measurement	TET2 CELF5 DCHS2 PRR23A RELN ZAN CPA3 PLXND1 RFX4 TG GMNC SEPSECS MTMR2	1.64e-03	1345	111	13	EFO_0010736
Disease	Astrocytosis	ITGB3 TNR	1.84e-03	17	111	2	C3887640
Disease	Gliosis	ITGB3 TNR	1.84e-03	17	111	2	C0017639
Disease	lung non-small cell carcinoma (is_implicated_in)	TET2 RUNX3 CBL KMT2D	1.91e-03	139	111	4	DOID:3908 (is_implicated_in)
Disease	eosinophil percentage of leukocytes	FLI1 NRIP1 IRAK2 RUNX3 ITGB3 TG SEPSECS GLB1 NFIL3	2.06e-03	746	111	9	EFO_0007991
Disease	matrix metalloproteinase 12 measurement	DYNC2H1 LILRB5	2.06e-03	18	111	2	EFO_0010590
Disease	alopecia	TET2 PRR23A HDAC4 RUNX3 ZBED6	2.21e-03	241	111	5	MONDO_0004907
Disease	Major Depressive Disorder	RELN CMYA5 LRP1 DLG3 MMP8	2.29e-03	243	111	5	C1269683
Disease	response to methotrexate, juvenile idiopathic arthritis	LMX1A CSMD1	2.30e-03	19	111	2	EFO_0002609, GO_0031427
Disease	cardiomyopathy (implicated_via_orthology)	DOC2A LRP1 DOC2B	2.46e-03	71	111	3	DOID:0050700 (implicated_via_orthology)
Disease	esophagus squamous cell carcinoma (is_marker_for)	TET2 RUNX3 KMT2D	2.77e-03	74	111	3	DOID:3748 (is_marker_for)
Disease	Nonsyndromic genetic hearing loss	MYO6 LMX1A FOXI1	2.98e-03	76	111	3	cv:C5680182
Disease	balding measurement	FOXE1 TET2 PRR23A NEK6 HDAC4 RUNX3 ZBED6 LRP1 LRP6	3.06e-03	792	111	9	EFO_0007825
Disease	Corneal astigmatism	FLI1 ZEB2 TNR	3.10e-03	77	111	3	EFO_1002040
Disease	age of onset of asthma	PABPC4 RUNX3 GLB1	3.33e-03	79	111	3	OBA_2001001
Disease	temperament and character inventory	TG SEPSECS	3.67e-03	24	111	2	EFO_0004825
Disease	Noonan Syndrome	LZTR1 CBL	3.67e-03	24	111	2	C0028326

Protein segments in the cluster

Peptide	Gene	Start	Entry
TSSNASKLMPYYLFH	nan	66	Q6ZS49
ASNFAAAPAFSHYMG	CDX4	41	O14627
AYAGMQHYTAAYPAA	CELF3	321	Q5SZQ8
LYSCNPGYAMHGSNT	CSMD1	1241	Q96PZ7
PLMGSAYLYQHSSTT	C2orf78	91	A6NCI8
LAVNHPGYMAFLTYD	CBLC	231	Q9ULV8
ADPAFYTYMMSHAAA	EVX1	251	P49640
TYGSSYFSGSHMFPT	CCNJL	416	Q8IV13
TRAGMSYYNSPGLHV	CCDC6	386	Q16204
GSPYAHMGSYQYQAS	DLX2	81	Q07687
AYAGMHHYAAAYPSA	CELF6	356	Q96J87
AHSSDPGALMYPNYA	MMP8	226	P22894
YATSGPMYLSDHENV	ERC1	66	Q8IUD2
TAGQERFHSLAPMYY	RAB31	61	Q13636
HSARYGNSSDMYTPL	RFX4	691	Q33E94
HFSDYGTYLCMASFP	MDGA1	406	Q8NFP4
FHSANTEALMYPLYN	MMP10	226	P09238
TFSSYYQHTSPVAAM	NPFFR1	31	Q9GZQ6
SSYPMASLYVGDLHS	PABPC4	6	Q13310
MQLYSSVCTHYPAGA	OTUD1	1	Q5VV17
YHLYGFQMPSSFACR	GJC3	156	Q8NFK1
FLYTSAMFSYMNPHS	OR10AD1	251	Q8NGE0
HSSYYSGMTGPQHPF	KIDINS220	1121	Q9ULH0
ISGRSSPHSTYYMGQ	KIDINS220	1406	Q9ULH0
VSTSYNHPVLGMYDA	HDAC4	221	P56524
APRYHHSAVVYGSSM	LZTR1	116	Q8N653
ANGSFFAPSRDMYSH	MID1IP1	76	Q9NPA3
FHSFIYPYMANGSLQ	IRAK2	281	O43187
RYAPMVAFFASHTYG	MMRN1	1096	Q13201
YPCHGMSSQLVRYSA	GALNT9	491	Q9HCQ5
MSYVPLQAAFHPGYS	HECW1	1181	Q76N89
NFTNPVYATLYMGGH	LRP1	4501	Q07954
TACMSDFSLYVFHPY	KIAA1109	4151	Q2LD37
IYAPSSHNKYAGESF	FOLH1	691	Q04609
HNSSNYTLPAFYMGN	GLB1	541	P16278
FYVGSYVHGAMQSPS	TSFM	211	P43897
DPADSGYLYLMTSHQ	PLXND1	526	Q9Y4D7
GNPIDHLYSMQNSYF	LMX1A	366	Q8TE12
YYGAGLFMCIQPTSH	OR2M7	251	Q8NG81
TNVTAHAAYSYMYAG	PTGER4	176	P35408
NYMGNSFSGYSHSPP	NFIL3	246	Q16649
TTAAHSLVGTPYYMS	NEK6	201	Q9HC98
GVAYMLYHVSQSPLF	LANCL3	71	Q6ZV70
SHYTMEFGYSSNSPS	LRP6	1496	O75581
ASFFNLRSPYNSHMG	NRIP1	1116	P48552
YGSYSNHVLYPVASM	MTMR2	556	Q13614
TNANYDSHPMLYFSR	DSE	36	Q9UL01
PHNSNFGYSYAKRMI	GFUS	136	Q13630
YQSYRHQAEFSMSPV	LILRB5	371	O75023
PSMAVYTHTGYNDHY	MEAK7	331	Q6P9B6
PYDAHTTGMTGAISY	IRX2	86	Q9BZI1
TEHHPSSTYYAGTMQ	RELN	2071	P78509
YSIVSPCFLTHGMSY	DCHS2	2806	Q6V1P9
SGSYRDPAAMHTGSY	HOXB5	31	P09067
DPAAMHTGSYGYNYN	HOXB5	36	P09067
GATPSRYMTFLHVYS	DYNC2H1	2866	Q8NCM8
ITFHSYSQMLLFPYG	CPA3	301	P15088
TKADHMGSYGPAFYQ	HLA-DOA	26	P06340
AHLAAMDVNGYSDPY	DOC2A	276	Q14183
AHLAAMDANGYSDPY	DOC2B	291	Q14184
MNPRQGYSLSGYYTH	ADAR	1	P55265
MHCSEPQRYTFFYSG	CMYA5	3981	Q8N3K9
LHPAFSGVQQYTAMY	CELF5	356	Q8N6W0
YPSDISYMPSYHAHQ	FLI1	381	Q01543
AAQVFYNNKGYHSMP	ABCA2	1726	Q9BZC7
YNNKGYHSMPTYLNS	ABCA2	1731	Q9BZC7
HLNDMYAPPDYASTF	DLG3	316	Q92796
VSGAPMSVYQDYSLH	EPHX3	196	Q9H6B9
HYSASTTMDYPSLGL	ITGB3	306	P05106
LAVTHPGYMAFLTYD	CBL	261	P22681
YSYSALIAMAIHGAP	FOXI1	126	Q12951
PYSSFVNHYNSPAMY	SEC24B	151	O95487
VNHYNSPAMYSASSS	SEC24B	156	O95487
GHYAMSTVSNAAYPS	SEC24B	181	O95487
PHTNSGAFVYGSMSF	MFSD12	396	Q6NUT3
FSLMTYDYSTAHQPG	CHID1	256	Q9BWS9
TSLHYMSPYQLNAYA	CPNE5	346	Q9HCH3
NHIYSSQGLIPFYMG	FAM166A	271	Q6J272
MSNESCLPYYTAHSY	GARIN3	1	Q8TC56
CLPYYTAHSYSSMSA	GARIN3	6	Q8TC56
PYDSGHIAMTYTGLS	PGGT1B	116	P53609
HLYYGTSSGSYQFSM	RUNX3	331	Q13761
FYLYTGRGPSSEAMH	WARS1	156	P23381
FPTLVGHTMCTYDFY	UPP2	206	O95045
AAGLYSSARSMFSPY	PRR23A	176	A6NEV1
TFSSAYQGNSLMYHD	TMEM151B	91	Q8IW70
YYTAHVSPNKTEMAF	GMNC	281	A6NCL1
TYPAYMHDAAAAAAA	FOXE1	156	O00358
YGTHYSNAAGVMHYL	NBEAL2	2156	Q6ZNJ1
MVSAAYASTKESYPH	PLIN3	41	O60664
HSYLALSYQEMNAPS	GUCY1B2	26	O75343
SESYNPHVRYGAAMA	PSMD1	641	Q99460
YSHHSMATLPYLDSG	ST3GAL2	26	Q16842
MNPSGLYITHHYYDN	ST8SIA5	326	O15466
YYLQTFGHNTMDAVP	SLC12A1	96	Q13621
YFSNMLGFYPSITHR	MT-ND5	521	P03915
PFTNGSYTFASMYHR	RNF220	61	Q5VTB9
SYTFASMYHRQGGVP	RNF220	66	Q5VTB9
NIMFFPVYYSGHLAT	SLC35F4	206	A4IF30
SSGDADSAHMEYPYG	SLC39A2	91	Q9NP94
QGPSHYMARYSTSAP	CLDN6	191	P56747
TPAYHYGTHYSSAMI	WDFY3	2781	Q8IZQ1
GSYSQHQSSYGPMKS	HNRNPA0	256	Q13151
YASDFPASYHGSKTM	TECPR1	891	Q7Z6L1
HYTATMYATNGPLTS	TNR	1016	Q92752
GQTYGDFLPDYSHFM	TTC41P	111	Q6P2S7
AIYYHASRAIPFGTM	TM9SF3	381	Q9HD45
APATGAHNYTLYFMS	SNRNP200	2096	O75643
DMHPYNYFSTPAFQR	ZBED6	421	P86452
PSHPYGFSNMRYISS	SLC30A9	296	Q6PML9
GYTFRGFMSHTNNYP	SEPSECS	416	Q9HD40
VASSSGHLYMYNLDP	WIPI1	331	Q5MNZ9
FLPHMAYTYPTGAAT	ZEB2	931	O60315
AYTYPTGAATFADMQ	ZEB2	936	O60315
SNYNVTSDYAVHPMS	PLEKHA5	126	Q9HAU0
YNLYAVSNHSGTTMG	USP2	541	O75604
YSAAPGMFNSSLHAL	TET2	1766	Q6N021
MQYFSHFIRSGNPNY	TG	2656	P01266
YLTMDIYAFPAGHAS	PLPP7	181	Q8NBV4
YPNGEGSYLHMESNS	ZAN	81	Q9Y493
MADFHSATALYPVGY	KMT2D	5196	O14686
DMPYRYHSSLGQLNF	NAGA	346	P17050
MQGGYPSRASFHELY	MYO6	701	Q9UM54
SLGTPSEYHYLTMGN	MYO7B	271	Q6PIF6
NYAFTMHYPAATLAG	NEUROD1	296	Q13562
KSYHYSMHYSALPGS	NEUROD2	321	Q15784