Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionchannel activity

CACNA1E PIEZO1 TRPC6 GABRQ PKDREJ LRRC8D RHCE RHD ITPR2 ITPR3 SLC9C1 KCNJ8 KCNJ16 KCNK5 HTR3D GABRA1 GABRA2

1.76e-0952510417GO:0015267
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

CACNA1E PIEZO1 TRPC6 GABRQ PKDREJ LRRC8D RHCE RHD ITPR2 ITPR3 SLC9C1 KCNJ8 KCNJ16 KCNK5 HTR3D GABRA1 GABRA2

1.81e-0952610417GO:0022803
GeneOntologyMolecularFunctionmonoatomic ion channel activity

CACNA1E PIEZO1 TRPC6 GABRQ PKDREJ LRRC8D ITPR2 ITPR3 SLC9C1 KCNJ8 KCNJ16 KCNK5 HTR3D GABRA1 GABRA2

1.55e-0845910415GO:0005216
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

CACNA1E PIEZO1 TRPC6 GABRQ SLC28A3 PKDREJ LRRC8D ITPR2 ITPR3 SLC8A2 SLC9C1 SLC8A3 KCNJ8 KCNJ16 KCNK5 HTR3D GABRA1 GABRA2

1.34e-0779310418GO:0015075
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

CACNA1E TRPC6 GABRQ SLC28A3 PKDREJ RHCE RHD ITPR2 ITPR3 SLC8A2 SLC9C1 SLC8A3 KCNJ8 KCNJ16 KCNK5 GABRA1 GABRA2

3.69e-0775810417GO:0015318
GeneOntologyMolecularFunctiongated channel activity

CACNA1E PIEZO1 GABRQ ITPR2 ITPR3 KCNJ8 KCNJ16 KCNK5 HTR3D GABRA1 GABRA2

1.36e-0633410411GO:0022836
GeneOntologyMolecularFunctiontransmembrane transporter activity

CACNA1E PIEZO1 TRPC6 GABRQ SLC28A3 PKDREJ LRRC8D RHCE RHD ITPR2 ITPR3 SLC8A2 SLC9C1 SLC8A3 KCNJ8 KCNJ16 KCNK5 HTR3D GABRA1 GABRA2

2.52e-06118010420GO:0022857
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

CACNA1E TRPC6 SLC28A3 PKDREJ RHCE RHD ITPR2 ITPR3 SLC8A2 SLC9C1 SLC8A3 KCNJ8 KCNJ16 KCNK5

4.61e-0662710414GO:0022890
GeneOntologyMolecularFunctionGABA receptor activity

GABRQ GABBR2 GABRA1 GABRA2

4.73e-06221044GO:0016917
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

CACNA1E TRPC6 SLC28A3 PKDREJ ITPR2 ITPR3 SLC8A2 SLC9C1 SLC8A3 KCNJ8 KCNJ16 KCNK5

5.49e-0646510412GO:0046873
GeneOntologyMolecularFunctionligand-gated monoatomic ion channel activity

GABRQ ITPR2 ITPR3 KCNJ8 KCNJ16 HTR3D GABRA1 GABRA2

7.68e-061931048GO:0015276
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

CACNA1E PIEZO1 TRPC6 SLC28A3 PKDREJ ITPR2 ITPR3 SLC8A2 SLC9C1 SLC8A3 KCNJ8 KCNJ16 KCNK5 HTR3D

8.86e-0666410414GO:0008324
GeneOntologyMolecularFunctionligand-gated channel activity

GABRQ ITPR2 ITPR3 KCNJ8 KCNJ16 HTR3D GABRA1 GABRA2

8.93e-061971048GO:0022834
GeneOntologyMolecularFunctiontransporter activity

CACNA1E PIEZO1 TRPC6 GABRQ SLC28A3 PKDREJ LRRC8D RHCE RHD ITPR2 ITPR3 SLC8A2 SLC9C1 SLC8A3 KCNJ8 KCNJ16 KCNK5 HTR3D GABRA1 GABRA2

9.48e-06128910420GO:0005215
GeneOntologyMolecularFunctionmonoatomic cation channel activity

CACNA1E PIEZO1 TRPC6 PKDREJ ITPR2 ITPR3 KCNJ8 KCNJ16 KCNK5 HTR3D

1.23e-0534310410GO:0005261
GeneOntologyMolecularFunctioncalcium ion transmembrane transporter activity

CACNA1E TRPC6 PKDREJ ITPR2 ITPR3 SLC8A2 SLC8A3

1.42e-051511047GO:0015085
GeneOntologyMolecularFunctioninositol 1,4,5 trisphosphate binding

TRPC6 ITPR2 ITPR3

4.79e-05141043GO:0070679
GeneOntologyMolecularFunctioninositol 1,4,5-trisphosphate-gated calcium channel activity

ITPR2 ITPR3

8.03e-0531042GO:0005220
GeneOntologyMolecularFunctioncalcium:monoatomic cation antiporter activity involved in regulation of postsynaptic cytosolic calcium ion concentration

SLC8A2 SLC8A3

8.03e-0531042GO:1905060
GeneOntologyMolecularFunctionGABA-gated chloride ion channel activity

GABRQ GABRA1 GABRA2

1.06e-04181043GO:0022851
GeneOntologyMolecularFunctionGABA-A receptor activity

GABRQ GABRA1 GABRA2

1.25e-04191043GO:0004890
GeneOntologyMolecularFunctiontransmitter-gated channel activity

GABRQ HTR3D GABRA1 GABRA2

3.68e-04651044GO:0022835
GeneOntologyMolecularFunctiontransmitter-gated monoatomic ion channel activity

GABRQ HTR3D GABRA1 GABRA2

3.68e-04651044GO:0022824
GeneOntologyMolecularFunctionprotein kinase C binding

UGT1A10 UGT1A8 UGT1A7 AKT2

3.91e-04661044GO:0005080
GeneOntologyMolecularFunctionretinoic acid binding

UGT1A10 UGT1A8 UGT1A7

4.09e-04281043GO:0001972
GeneOntologyMolecularFunctioncalcium channel activity

CACNA1E TRPC6 PKDREJ ITPR2 ITPR3

5.74e-041291045GO:0005262
GeneOntologyMolecularFunctionextracellular ligand-gated monoatomic ion channel activity

GABRQ HTR3D GABRA1 GABRA2

7.02e-04771044GO:0005230
GeneOntologyMolecularFunctionglucuronosyltransferase activity

UGT1A10 UGT1A8 UGT1A7

7.96e-04351043GO:0015020
GeneOntologyMolecularFunctionligand-gated monoatomic cation channel activity

ITPR2 ITPR3 KCNJ8 KCNJ16 HTR3D

8.32e-041401045GO:0099094
GeneOntologyMolecularFunctioncalcium:sodium antiporter activity

SLC8A2 SLC8A3

1.18e-03101042GO:0005432
GeneOntologyMolecularFunctionUDP-glycosyltransferase activity

UGT1A10 UGT1A8 UGT1A7 COLGALT2 LFNG

1.24e-031531045GO:0008194
GeneOntologyMolecularFunctionhelicase activity

DDX19B DDX19A SETX ATRX RECQL5

1.43e-031581045GO:0004386
GeneOntologyMolecularFunctionbenzodiazepine receptor activity

GABRA1 GABRA2

1.43e-03111042GO:0008503
GeneOntologyMolecularFunctionmetal cation:monoatomic cation antiporter activity

SLC8A2 SLC9C1 SLC8A3

1.46e-03431043GO:0140828
GeneOntologyMolecularFunctionammonium channel activity

RHCE RHD

1.71e-03121042GO:0008519
GeneOntologyMolecularFunctionneurotransmitter receptor activity

GABRQ HTR3D GABRA1 GABRA2

1.86e-031001044GO:0030594
GeneOntologyMolecularFunctionretinoid binding

UGT1A10 UGT1A8 UGT1A7

2.00e-03481043GO:0005501
GeneOntologyMolecularFunctioncalcium:monoatomic cation antiporter activity

SLC8A2 SLC8A3

2.02e-03131042GO:0015368
GeneOntologyMolecularFunctionmonoatomic anion channel activity

GABRQ LRRC8D GABRA1 GABRA2

2.07e-031031044GO:0005253
GeneOntologyMolecularFunctionisoprenoid binding

UGT1A10 UGT1A8 UGT1A7

2.12e-03491043GO:0019840
GeneOntologyMolecularFunctionligand-gated monoatomic anion channel activity

GABRQ GABRA1 GABRA2

2.25e-03501043GO:0099095
GeneOntologyMolecularFunctionmonocarboxylic acid binding

NAPEPLD UGT1A10 UGT1A8 UGT1A7

2.38e-031071044GO:0033293
GeneOntologyMolecularFunctiontransmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential

HTR3D GABRA1 GABRA2

3.27e-03571043GO:1904315
GeneOntologyMolecularFunctionneurotransmitter receptor activity involved in regulation of postsynaptic membrane potential

HTR3D GABRA1 GABRA2

3.79e-03601043GO:0099529
GeneOntologyMolecularFunctionintracellularly gated calcium channel activity

ITPR2 ITPR3

3.89e-03181042GO:0015278
GeneOntologyMolecularFunctionminus-end-directed microtubule motor activity

DYNC2H1 DNAH5

3.89e-03181042GO:0008569
GeneOntologyMolecularFunctionglycosyltransferase activity

ST6GALNAC1 UGT1A10 UGT1A8 UGT1A7 COLGALT2 LFNG

3.98e-032881046GO:0016757
GeneOntologyMolecularFunctionhexosyltransferase activity

UGT1A10 UGT1A8 UGT1A7 COLGALT2 LFNG

4.96e-032111045GO:0016758
GeneOntologyMolecularFunctionfatty acid binding

UGT1A10 UGT1A8 UGT1A7

5.61e-03691043GO:0005504
GeneOntologyMolecularFunctioncatalytic activity, acting on a nucleic acid

DDX19B DDX19A SETX ATRX POLG DNASE2B PSTK RECQL5 THG1L

6.53e-036451049GO:0140640
GeneOntologyBiologicalProcessflavone metabolic process

UGT1A10 UGT1A8 UGT1A7 LCT

9.08e-0961044GO:0051552
GeneOntologyBiologicalProcessflavonoid metabolic process

UGT1A10 UGT1A8 UGT1A7 LCT

4.21e-07131044GO:0009812
GeneOntologyBiologicalProcessinorganic ion transmembrane transport

CACNA1E TRPC6 GABRQ SLC28A3 TLR9 PKDREJ RHCE RHD ITPR2 ITPR3 SLC8A2 SLC9C1 SLC8A3 KCNJ8 KCNJ16 KCNK5 HTR3D GABRA1 GABRA2

6.94e-07101710419GO:0098660
GeneOntologyBiologicalProcessestrogen catabolic process

UGT1A10 UGT1A8 UGT1A7

1.24e-0651043GO:0006711
GeneOntologyBiologicalProcessphenylpropanoid catabolic process

UGT1A10 UGT1A8 UGT1A7

2.46e-0661043GO:0046271
GeneOntologyBiologicalProcesscoumarin catabolic process

UGT1A10 UGT1A8 UGT1A7

2.46e-0661043GO:0046226
GeneOntologyBiologicalProcessimport across plasma membrane

CACNA1E LRRC8D SLC8A2 SLC9C1 SLC8A3 KCNJ8 KCNJ16 KCNK5 AKT2

2.50e-062301049GO:0098739
GeneOntologyBiologicalProcessmonoatomic ion transmembrane transport

CACNA1E PIEZO1 TRPC6 GABRQ SLC28A3 TLR9 PKDREJ LRRC8D ITPR2 ITPR3 SLC8A2 SLC9C1 SLC8A3 KCNJ8 KCNJ16 KCNK5 HTR3D GABRA1 GABRA2

2.72e-06111510419GO:0034220
GeneOntologyBiologicalProcesshormone catabolic process

UGT1A10 UGT1A8 UGT1A7 HSD17B11

3.42e-06211044GO:0042447
GeneOntologyBiologicalProcessmonoatomic ion transport

CACNA1E SGK1 PIEZO1 TRPC6 GABRQ SLC28A3 TLR9 PKDREJ LRRC8D ITPR2 ITPR3 SLC8A2 SLC9C1 SLC8A3 KCNJ8 KCNJ16 KCNK5 HTR3D AKT2 GABRA1 GABRA2

4.16e-06137410421GO:0006811
GeneOntologyBiologicalProcessinorganic ion import across plasma membrane

CACNA1E SLC8A2 SLC9C1 SLC8A3 KCNJ8 KCNJ16 KCNK5

7.69e-061421047GO:0099587
GeneOntologyBiologicalProcessinorganic cation import across plasma membrane

CACNA1E SLC8A2 SLC9C1 SLC8A3 KCNJ8 KCNJ16 KCNK5

7.69e-061421047GO:0098659
GeneOntologyBiologicalProcessphenylpropanoid metabolic process

UGT1A10 UGT1A8 UGT1A7

1.46e-05101043GO:0009698
GeneOntologyBiologicalProcesscoumarin metabolic process

UGT1A10 UGT1A8 UGT1A7

1.46e-05101043GO:0009804
GeneOntologyBiologicalProcessinorganic cation transmembrane transport

CACNA1E TRPC6 SLC28A3 TLR9 PKDREJ RHCE RHD ITPR2 ITPR3 SLC8A2 SLC9C1 SLC8A3 KCNJ8 KCNJ16 KCNK5 HTR3D

1.48e-0592210416GO:0098662
GeneOntologyBiologicalProcesssteroid catabolic process

UGT1A10 UGT1A8 UGT1A7 HSD17B11

2.52e-05341044GO:0006706
GeneOntologyBiologicalProcessgamma-aminobutyric acid signaling pathway

GABRQ GABBR2 GABRA1 GABRA2

2.83e-05351044GO:0007214
GeneOntologyBiologicalProcessregulation of postsynaptic membrane potential

SLC8A2 SLC8A3 AFDN HTR3D NLGN2 GABRA1 GABRA2

3.57e-051801047GO:0060078
GeneOntologyBiologicalProcessretinoid metabolic process

PLB1 NAPEPLD UGT1A8 UGT1A7 AWAT2

8.78e-05891045GO:0001523
GeneOntologyBiologicalProcesshormone metabolic process

PLB1 UGT1A10 UGT1A8 UGT1A7 CYP17A1 BCHE AWAT2 HSD17B11

1.01e-042861048GO:0042445
GeneOntologyBiologicalProcesschemical synaptic transmission, postsynaptic

SLC8A2 SLC8A3 AFDN HTR3D NLGN2 GABRA1

1.01e-041471046GO:0099565
GeneOntologyBiologicalProcessditerpenoid metabolic process

PLB1 NAPEPLD UGT1A8 UGT1A7 AWAT2

1.14e-04941045GO:0016101
GeneOntologyBiologicalProcessregulation of membrane potential

PIEZO1 GABRQ SLC8A2 SLC8A3 KCNJ8 KCNK5 AFDN HTR3D NLGN2 GABRA1 GABRA2

1.20e-0455910411GO:0042391
GeneOntologyBiologicalProcesslipid catabolic process

PLB1 NAPEPLD UGT1A10 UGT1A8 UGT1A7 LCT AKT2 ALDH3B2 HSD17B11

1.36e-043821049GO:0016042
GeneOntologyBiologicalProcessestrogen metabolic process

UGT1A10 UGT1A8 UGT1A7 HSD17B11

1.37e-04521044GO:0008210
GeneOntologyBiologicalProcessmetal ion transport

CACNA1E SGK1 TRPC6 SLC28A3 TLR9 PKDREJ ITPR2 ITPR3 SLC8A2 SLC9C1 SLC8A3 KCNJ8 KCNJ16 KCNK5 AKT2

1.45e-04100010415GO:0030001
GeneOntologyBiologicalProcesscellular glucuronidation

UGT1A10 UGT1A8 UGT1A7

1.55e-04211043GO:0052695
GeneOntologyBiologicalProcesscalcium ion transmembrane transport

CACNA1E TRPC6 TLR9 PKDREJ ITPR2 ITPR3 SLC8A2 SLC8A3 KCNJ8

1.65e-043921049GO:0070588
GeneOntologyBiologicalProcessterpenoid metabolic process

PLB1 NAPEPLD UGT1A8 UGT1A7 AWAT2

1.92e-041051045GO:0006721
GeneOntologyBiologicalProcessmonoatomic cation transport

CACNA1E SGK1 PIEZO1 TRPC6 SLC28A3 TLR9 PKDREJ ITPR2 ITPR3 SLC8A2 SLC9C1 SLC8A3 KCNJ8 KCNJ16 KCNK5 AKT2

2.16e-04115710416GO:0006812
GeneOntologyBiologicalProcessanterograde trans-synaptic signaling

CACNA1E GABRQ BCHE GABBR2 KMO ITPR3 SLC8A2 SLC8A3 KCNJ8 AFDN HTR3D NLGN2 GABRA1 GABRA2

2.39e-0493110414GO:0098916
GeneOntologyBiologicalProcesschemical synaptic transmission

CACNA1E GABRQ BCHE GABBR2 KMO ITPR3 SLC8A2 SLC8A3 KCNJ8 AFDN HTR3D NLGN2 GABRA1 GABRA2

2.39e-0493110414GO:0007268
GeneOntologyBiologicalProcessflavonoid glucuronidation

UGT1A8 UGT1A7

2.49e-0451042GO:0052696
GeneOntologyBiologicalProcesstrans-synaptic signaling

CACNA1E GABRQ BCHE GABBR2 KMO ITPR3 SLC8A2 SLC8A3 KCNJ8 AFDN HTR3D NLGN2 GABRA1 GABRA2

2.61e-0493910414GO:0099537
GeneOntologyBiologicalProcessmonoatomic cation transmembrane transport

CACNA1E PIEZO1 TRPC6 SLC28A3 TLR9 PKDREJ ITPR2 ITPR3 SLC8A2 SLC9C1 SLC8A3 KCNJ8 KCNJ16 KCNK5

2.70e-0494210414GO:0098655
GeneOntologyBiologicalProcessglucuronate metabolic process

UGT1A10 UGT1A8 UGT1A7

2.98e-04261043GO:0019585
GeneOntologyBiologicalProcessuronic acid metabolic process

UGT1A10 UGT1A8 UGT1A7

2.98e-04261043GO:0006063
GeneOntologyBiologicalProcessmodulation of excitatory postsynaptic potential

SLC8A2 SLC8A3 AFDN NLGN2

3.26e-04651044GO:0098815
GeneOntologyBiologicalProcessammonium homeostasis

RHCE RHD

3.73e-0461042GO:0097272
GeneOntologyBiologicalProcesssynaptic signaling

CACNA1E GABRQ BCHE GABBR2 KMO ITPR3 SLC8A2 SLC8A3 KCNJ8 AFDN HTR3D NLGN2 GABRA1 GABRA2

3.86e-0497610414GO:0099536
GeneOntologyBiologicalProcessinhibitory synapse assembly

NLGN2 GABRA1 GABRA2

4.58e-04301043GO:1904862
GeneOntologyBiologicalProcessexcitatory postsynaptic potential

SLC8A2 SLC8A3 AFDN HTR3D NLGN2

5.14e-041301045GO:0060079
GeneOntologyBiologicalProcesssynaptic transmission, GABAergic

GABBR2 NLGN2 GABRA1 GABRA2

5.35e-04741044GO:0051932
GeneOntologyBiologicalProcessresponse to iron(II) ion

ACO1 LCT

6.91e-0481042GO:0010040
GeneOntologyBiologicalProcesslearning

CACNA1E PDE1B SGK1 BCHE SLC8A2 SLC8A3

7.22e-042121046GO:0007612
GeneOntologyBiologicalProcessxenobiotic metabolic process

UGT1A10 UGT1A8 UGT1A7 BCHE SLC28A3

7.43e-041411045GO:0006805
GeneOntologyBiologicalProcessisoprenoid metabolic process

PLB1 NAPEPLD UGT1A8 UGT1A7 AWAT2

8.17e-041441045GO:0006720
GeneOntologyBiologicalProcessmonoatomic cation homeostasis

SGK1 ACO1 TRPC6 RHCE RHD ITPR2 ITPR3 SLC8A2 SLC9C1 SLC8A3 KCNJ16

8.58e-0470510411GO:0055080
GeneOntologyBiologicalProcessglutamate secretion, neurotransmission

KMO KCNJ8

8.86e-0491042GO:0061535
GeneOntologyBiologicalProcessperipheral nervous system myelin maintenance

AKT2 PLEC

8.86e-0491042GO:0032287
GeneOntologyBiologicalProcesscellular response to xenobiotic stimulus

UGT1A10 UGT1A8 UGT1A7 BCHE SLC28A3 RECQL5

9.17e-042221046GO:0071466
GeneOntologyBiologicalProcesscellular response to organic cyclic compound

NR2E3 SGK1 TLR9 ITPR2 ITPR3 SLC8A3 RECQL5 HTR3D AKT2 GABRA1

9.64e-0460510410GO:0071407
GeneOntologyBiologicalProcessmonoatomic ion homeostasis

SGK1 ACO1 TRPC6 RHCE RHD ITPR2 ITPR3 SLC8A2 SLC9C1 SLC8A3 KCNJ16

9.84e-0471710411GO:0050801
GeneOntologyBiologicalProcesscalcium ion transport

CACNA1E TRPC6 TLR9 PKDREJ ITPR2 ITPR3 SLC8A2 SLC8A3 KCNJ8

1.09e-035091049GO:0006816
GeneOntologyBiologicalProcesshost-mediated regulation of intestinal microbiota composition

ST6GALNAC1 NAPEPLD

1.10e-03101042GO:0048874
GeneOntologyBiologicalProcessmarginal zone B cell differentiation

DOCK10 LFNG

1.10e-03101042GO:0002315
GeneOntologyCellularComponentGABA receptor complex

GABRQ GABBR2 GABRA1 GABRA2

3.37e-06211054GO:1902710
GeneOntologyCellularComponentpostsynaptic membrane

CACNA1E NAPEPLD GABRQ GABBR2 SLC8A2 SLC8A3 AFDN HTR3D NLGN2 GABRA1 GABRA2

6.15e-0640510511GO:0045211
GeneOntologyCellularComponentmonoatomic ion channel complex

CACNA1E TRPC6 GABRQ LRRC8D KCNJ8 KCNJ16 KCNK5 HTR3D GABRA1 GABRA2

2.08e-0537810510GO:0034702
GeneOntologyCellularComponentsynaptic membrane

CACNA1E NAPEPLD GABRQ GABBR2 SLC8A2 SLC8A3 KCNJ8 AFDN HTR3D NLGN2 GABRA1 GABRA2

3.64e-0558310512GO:0097060
GeneOntologyCellularComponentnuclear outer membrane-endoplasmic reticulum membrane network

NAPEPLD SGK1 UGT1A10 UGT1A8 UGT1A7 CYP17A1 PIEZO1 SLC28A3 BFAR XPO1 TLR9 LRRC8D AWAT2 ITPR2 ITPR3 SLC8A3 STX5 TMED9

1.02e-04132710518GO:0042175
GeneOntologyCellularComponentGABA-A receptor complex

GABRQ GABRA1 GABRA2

1.13e-04191053GO:1902711
GeneOntologyCellularComponentendoplasmic reticulum membrane

NAPEPLD SGK1 UGT1A10 UGT1A8 UGT1A7 CYP17A1 PIEZO1 SLC28A3 BFAR TLR9 LRRC8D AWAT2 ITPR2 ITPR3 SLC8A3 STX5 TMED9

2.36e-04129310517GO:0005789
GeneOntologyCellularComponentendoplasmic reticulum subcompartment

NAPEPLD SGK1 UGT1A10 UGT1A8 UGT1A7 CYP17A1 PIEZO1 SLC28A3 BFAR TLR9 LRRC8D AWAT2 ITPR2 ITPR3 SLC8A3 STX5 TMED9

2.49e-04129910517GO:0098827
GeneOntologyCellularComponentsarcoplasm

ITPR2 ITPR3 SLC8A3 AKT2 PLEC

2.76e-041141055GO:0016528
GeneOntologyCellularComponenttransmembrane transporter complex

CACNA1E TRPC6 GABRQ LRRC8D KCNJ8 KCNJ16 KCNK5 HTR3D GABRA1 GABRA2

3.04e-0452310510GO:1902495
GeneOntologyCellularComponenttransporter complex

CACNA1E TRPC6 GABRQ LRRC8D KCNJ8 KCNJ16 KCNK5 HTR3D GABRA1 GABRA2

4.51e-0455010510GO:1990351
GeneOntologyCellularComponentpresynapse

CACNA1E NAPEPLD POLG GABBR2 NUFIP1 ITPR3 SLC8A2 SLC8A3 KCNJ8 TMED9 AFDN NLGN2 GABRA2

4.95e-0488610513GO:0098793
GeneOntologyCellularComponentpresynaptic membrane

CACNA1E NAPEPLD GABBR2 KCNJ8 AFDN NLGN2 GABRA2

5.01e-042771057GO:0042734
GeneOntologyCellularComponentplatelet dense tubular network membrane

ITPR2 ITPR3

8.79e-0491052GO:0031095
GeneOntologyCellularComponentbrush border

PLB1 SLC28A3 LCT ITPR3 PLEC

1.02e-031521055GO:0005903
GeneOntologyCellularComponentankyrin-1 complex

RHCE RHD

1.10e-03101052GO:0170014
GeneOntologyCellularComponentplatelet dense tubular network

ITPR2 ITPR3

1.33e-03111052GO:0031094
GeneOntologyCellularComponentGABA-ergic synapse

CACNA1E GABBR2 NLGN2 GABRA1 GABRA2

1.44e-031641055GO:0098982
GeneOntologyCellularComponentcell projection membrane

PLB1 NAPEPLD PIEZO1 SLC28A3 SLC9C1 AKT2 GABRA1 GABRA2

1.49e-034311058GO:0031253
GeneOntologyCellularComponentreceptor complex

PLXNA3 GABRQ GABBR2 ITPR2 ITPR3 HTR3D OSMR GABRA1 GABRA2

2.63e-035811059GO:0043235
GeneOntologyCellularComponenttranscription elongation factor complex

MMS22L ICE1 NUFIP1

2.81e-03561053GO:0008023
GeneOntologyCellularComponentchloride channel complex

GABRQ GABRA1 GABRA2

2.96e-03571053GO:0034707
GeneOntologyCellularComponentmembrane protein complex

CACNA1E TRPC6 GABRQ GABBR2 LRRC8D RHCE RHD STX5 KCNJ8 KCNJ16 KCNK5 AFDN HTR3D OSMR GABRA1 GABRA2

3.23e-03149810516GO:0098796
DomainDUF3398

DOCK9 DOCK10 DOCK6

3.13e-0661023PF11878
DomainDOCK_C/D_N

DOCK9 DOCK10 DOCK6

3.13e-0661023IPR021816
DomainDOCK_C

DOCK9 DOCK10 DOCK6

2.53e-05111023IPR010703
DomainDHR-1_domain

DOCK9 DOCK10 DOCK6

2.53e-05111023IPR027007
DomainDHR_2

DOCK9 DOCK10 DOCK6

2.53e-05111023PS51651
DomainDHR_1

DOCK9 DOCK10 DOCK6

2.53e-05111023PS51650
DomainDOCK-C2

DOCK9 DOCK10 DOCK6

2.53e-05111023PF14429
DomainDHR-2

DOCK9 DOCK10 DOCK6

2.53e-05111023IPR027357
DomainDHR-2

DOCK9 DOCK10 DOCK6

2.53e-05111023PF06920
DomainDOCK

DOCK9 DOCK10 DOCK6

2.53e-05111023IPR026791
DomainInsP3_rcpt-bd

ITPR2 ITPR3

8.83e-0531022IPR000493
DomainNa_Ca_Ex

SLC8A2 SLC8A3

8.83e-0531022IPR004836
DomainNa_Ca_Ex_C-exten

SLC8A2 SLC8A3

8.83e-0531022IPR032452
DomainNa_Ca_ex_C

SLC8A2 SLC8A3

8.83e-0531022PF16494
DomainNeur_chan_memb

GABRQ HTR3D GABRA1 GABRA2

1.15e-04461024PF02932
DomainNeur_chan_LBD

GABRQ HTR3D GABRA1 GABRA2

1.25e-04471024PF02931
DomainNEUROTR_ION_CHANNEL

GABRQ HTR3D GABRA1 GABRA2

1.25e-04471024PS00236
DomainNeurotrans-gated_channel_TM

GABRQ HTR3D GABRA1 GABRA2

1.25e-04471024IPR006029
Domain-

GABRQ HTR3D GABRA1 GABRA2

1.25e-044710242.70.170.10
DomainNeur_channel

GABRQ HTR3D GABRA1 GABRA2

1.25e-04471024IPR006201
DomainNeur_chan_lig-bd

GABRQ HTR3D GABRA1 GABRA2

1.25e-04471024IPR006202
DomainUDPGT

UGT1A10 UGT1A8 UGT1A7

1.96e-04211023PF00201
DomainUDPGT

UGT1A10 UGT1A8 UGT1A7

1.96e-04211023PS00375
DomainUDP_glucos_trans

UGT1A10 UGT1A8 UGT1A7

1.96e-04211023IPR002213
DomainGABAA/Glycine_rcpt

GABRQ GABRA1 GABRA2

2.59e-04231023IPR006028
DomainPKNOX/Meis_N

MEIS3 MEIS1

2.92e-0451022IPR032453
DomainAmmonium_transpt

RHCE RHD

2.92e-0451022IPR001905
DomainMeis_PKNOX_N

MEIS3 MEIS1

2.92e-0451022PF16493
DomainAmmonium_transp

RHCE RHD

2.92e-0451022PF00909
DomainNH4_transpt_AmtB-like_dom

RHCE RHD

2.92e-0451022IPR024041
DomainRhesusRHD

RHCE RHD

2.92e-0451022IPR002229
DomainIon_trans_dom

CACNA1E TRPC6 ITPR2 ITPR3 SLC9C1

4.03e-041141025IPR005821
DomainIon_trans

CACNA1E TRPC6 ITPR2 ITPR3 SLC9C1

4.03e-041141025PF00520
DomainRIH_assoc

ITPR2 ITPR3

4.37e-0461022PF08454
DomainRIH_assoc-dom

ITPR2 ITPR3

4.37e-0461022IPR013662
DomainRIH_dom

ITPR2 ITPR3

4.37e-0461022IPR000699
DomainIns145_P3_rcpt

ITPR2 ITPR3

4.37e-0461022IPR014821
DomainRyanodine_recept-rel

ITPR2 ITPR3

4.37e-0461022IPR015925
Domain-

ITPR2 ITPR3

4.37e-04610221.25.10.30
DomainRYDR_ITPR

ITPR2 ITPR3

4.37e-0461022PF01365
DomainGABAAa_rcpt

GABRA1 GABRA2

4.37e-0461022IPR001390
DomainIns145_P3_rec

ITPR2 ITPR3

4.37e-0461022PF08709
DomainARM-type_fold

MROH2A DOCK9 ARFGEF1 XPO1 ITPR2 NOC4L TTI1 UNC79

5.41e-043391028IPR016024
Domain-

RHCE RHD

6.09e-04710221.10.3430.10
DomainAmmonium/urea_transptr

RHCE RHD

6.09e-0471022IPR029020
DomainARM-like

SETX MROH2A DOCK10 ARFGEF1 XPO1 NOC4L TTI1

7.01e-042701027IPR011989
DomainCalx_beta

SLC8A2 SLC8A3

8.09e-0481022SM00237
DomainDHC_N1

DYNC2H1 DNAH5

8.09e-0481022PF08385
DomainDynein_heavy_dom-1

DYNC2H1 DNAH5

8.09e-0481022IPR013594
DomainCalx_beta

SLC8A2 SLC8A3

1.04e-0391022IPR003644
DomainNaCa_Exmemb

SLC8A2 SLC8A3

1.04e-0391022IPR004837
DomainNa_Ca_ex

SLC8A2 SLC8A3

1.04e-0391022PF01699
DomainCalx-beta

SLC8A2 SLC8A3

1.04e-0391022PF03160
DomainMIR

ITPR2 ITPR3

1.29e-03101022PS50919
DomainMIR

ITPR2 ITPR3

1.29e-03101022PF02815
DomainMIR

ITPR2 ITPR3

1.29e-03101022SM00472
DomainMIR_motif

ITPR2 ITPR3

1.29e-03101022IPR016093
DomainNeurotransmitter_ion_chnl_CS

GABRQ GABRA1 GABRA2

1.90e-03451023IPR018000
DomainCarboxylesterase_B_CS

BCHE NLGN2

2.22e-03131022IPR019819
DomainDynein_heavy_chain_D4_dom

DYNC2H1 DNAH5

2.57e-03141022IPR024317
DomainDynein_HC_stalk

DYNC2H1 DNAH5

2.57e-03141022IPR024743
DomainCARBOXYLESTERASE_B_2

BCHE NLGN2

2.57e-03141022PS00941
DomainDynein_heavy_dom-2

DYNC2H1 DNAH5

2.57e-03141022IPR013602
DomainDHC_N2

DYNC2H1 DNAH5

2.57e-03141022PF08393
DomainMT

DYNC2H1 DNAH5

2.57e-03141022PF12777
DomainAAA_8

DYNC2H1 DNAH5

2.57e-03141022PF12780
DomainATPase_dyneun-rel_AAA

DYNC2H1 DNAH5

2.57e-03141022IPR011704
DomainCOesterase

BCHE NLGN2

2.57e-03141022PF00135
DomainCarbesteraseB

BCHE NLGN2

2.57e-03141022IPR002018
DomainAAA_5

DYNC2H1 DNAH5

2.57e-03141022PF07728
DomainHelicase_C

DDX19B DDX19A ATRX RECQL5

2.81e-031071024PF00271
DomainHELICc

DDX19B DDX19A ATRX RECQL5

2.81e-031071024SM00490
DomainHelicase_C

DDX19B DDX19A ATRX RECQL5

2.91e-031081024IPR001650
DomainDHC_fam

DYNC2H1 DNAH5

2.96e-03151022IPR026983
DomainDynein_heavy_dom

DYNC2H1 DNAH5

2.96e-03151022IPR004273
DomainDynein_heavy

DYNC2H1 DNAH5

2.96e-03151022PF03028
DomainHELICASE_CTER

DDX19B DDX19A ATRX RECQL5

3.01e-031091024PS51194
DomainHELICASE_ATP_BIND_1

DDX19B DDX19A ATRX RECQL5

3.01e-031091024PS51192
DomainDEXDc

DDX19B DDX19A ATRX RECQL5

3.01e-031091024SM00487
DomainHelicase_ATP-bd

DDX19B DDX19A ATRX RECQL5

3.11e-031101024IPR014001
DomainK_chnl_inward-rec_Kir_cyto

KCNJ8 KCNJ16

3.37e-03161022IPR013518
DomainIRK

KCNJ8 KCNJ16

3.37e-03161022PF01007
Domain-

KCNJ8 KCNJ16

3.37e-031610222.60.40.1400
DomainK_chnl_inward-rec_Kir

KCNJ8 KCNJ16

3.37e-03161022IPR016449
DomainHomeobox_KN

MEIS3 MEIS1

3.81e-03171022PF05920
DomainHomeobox_KN_domain

MEIS3 MEIS1

3.81e-03171022IPR008422
PathwayREACTOME_PLATELET_CALCIUM_HOMEOSTASIS

TRPC6 ITPR2 ITPR3 SLC8A2 SLC8A3

5.78e-0727875MM15053
PathwayREACTOME_PLATELET_CALCIUM_HOMEOSTASIS

TRPC6 ITPR2 ITPR3 SLC8A2 SLC8A3

7.01e-0728875M924
PathwayREACTOME_PLATELET_HOMEOSTASIS

PDE1B TRPC6 ITPR2 ITPR3 SLC8A2 SLC8A3

7.18e-0676876MM15051
PathwayREACTOME_PLATELET_HOMEOSTASIS

PDE1B TRPC6 ITPR2 ITPR3 SLC8A2 SLC8A3

1.47e-0586876M916
PathwayREACTOME_GABA_RECEPTOR_ACTIVATION

GABRQ GABBR2 KCNJ16 GABRA1 GABRA2

3.33e-0560875MM15708
PathwayREACTOME_GABA_RECEPTOR_ACTIVATION

GABRQ GABBR2 KCNJ16 GABRA1 GABRA2

3.33e-0560875M976
PathwayWP_GABA_RECEPTOR_SIGNALING

GABRQ GABBR2 GABRA1 GABRA2

3.75e-0531874M39369
PathwayREACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS

TRPC6 ITPR2 ITPR3

6.21e-0513873MM14553
PathwayREACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS

TRPC6 ITPR2 ITPR3

1.20e-0416873M26945
PathwayREACTOME_ASPIRIN_ADME

UGT1A10 UGT1A8 UGT1A7 BCHE

1.66e-0445874MM15694
PathwayREACTOME_NEURONAL_SYSTEM

CACNA1E GABRQ BCHE GABBR2 KCNJ8 KCNJ16 HTR3D NLGN2 GABRA1 GABRA2

2.15e-044118710M735
PathwayREACTOME_TRANSMISSION_ACROSS_CHEMICAL_SYNAPSES

CACNA1E GABRQ BCHE GABBR2 KCNJ16 HTR3D GABRA1 GABRA2

2.58e-04270878M15514
PathwayWP_ESTROGEN_METABOLISM

UGT1A10 UGT1A8 UGT1A7

3.21e-0422873MM15888
PathwayREACTOME_ION_HOMEOSTASIS

ITPR2 ITPR3 SLC8A2 SLC8A3

3.38e-0454874M27460
PathwayREACTOME_ION_HOMEOSTASIS

ITPR2 ITPR3 SLC8A2 SLC8A3

3.38e-0454874MM15202
PathwayKEGG_STEROID_HORMONE_BIOSYNTHESIS

UGT1A10 UGT1A8 UGT1A7 CYP17A1

3.63e-0455874M14933
PathwayKEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_PRKN_TO_MGLUR1_SIGNALING_PATHWAY

ITPR2 ITPR3

3.72e-045872M49000
PathwayREACTOME_GLUCURONIDATION

UGT1A10 UGT1A8 UGT1A7

4.18e-0424873MM14599
PathwayREACTOME_CARDIAC_CONDUCTION

ITPR2 ITPR3 SLC8A2 SLC8A3 KCNK5

4.34e-04103875MM15196
PathwayREACTOME_GLUCURONIDATION

UGT1A10 UGT1A8 UGT1A7

4.73e-0425873M17787
PathwayWP_GLUCURONIDATION

UGT1A10 UGT1A8 UGT1A7

4.73e-0425873MM15820
PathwayREACTOME_EFFECTS_OF_PIP2_HYDROLYSIS

TRPC6 ITPR2 ITPR3

4.73e-0425873MM14511
PathwayKEGG_ASCORBATE_AND_ALDARATE_METABOLISM

UGT1A10 UGT1A8 UGT1A7

4.73e-0425873M605
PathwayWP_GLUCURONIDATION

UGT1A10 UGT1A8 UGT1A7

5.33e-0426873M39404
PathwayKEGG_MEDICUS_REFERENCE_CA2_PLCD_ITPR_SIGNALING_PATHWAY

ITPR2 ITPR3

5.56e-046872M47960
PathwayREACTOME_DRUG_ADME

UGT1A10 UGT1A8 UGT1A7 BCHE SLC28A3

5.63e-04109875M45012
PathwayREACTOME_EFFECTS_OF_PIP2_HYDROLYSIS

TRPC6 ITPR2 ITPR3

5.97e-0427873M12123
PathwayKEGG_RETINOL_METABOLISM

UGT1A10 UGT1A8 UGT1A7 AWAT2

6.48e-0464874M9488
PathwayKEGG_PENTOSE_AND_GLUCURONATE_INTERCONVERSIONS

UGT1A10 UGT1A8 UGT1A7

6.65e-0428873M19580
PathwayKEGG_CALCIUM_SIGNALING_PATHWAY

CACNA1E PDE1B ITPR2 ITPR3 SLC8A2 SLC8A3

8.07e-04178876M2890
PathwayPID_CDC42_REG_PATHWAY

DOCK9 DOCK10 DOCK6

8.17e-0430873M83
PathwayREACTOME_DRUG_ADME

UGT1A10 UGT1A8 UGT1A7 BCHE SLC28A3

8.39e-04119875MM15692
PathwayKEGG_METABOLISM_OF_XENOBIOTICS_BY_CYTOCHROME_P450

UGT1A10 UGT1A8 UGT1A7 ALDH3B2

9.10e-0470874M16794
PathwayKEGG_DRUG_METABOLISM_CYTOCHROME_P450

UGT1A10 UGT1A8 UGT1A7 ALDH3B2

1.01e-0372874M9257
PathwayREACTOME_NEURONAL_SYSTEM

CACNA1E GABRQ GABBR2 KCNJ8 KCNJ16 NLGN2 GABRA1 GABRA2

1.07e-03335878MM14503
PathwayREACTOME_CARDIAC_CONDUCTION

ITPR2 ITPR3 SLC8A2 SLC8A3 KCNK5

1.25e-03130875M27454
PathwayREACTOME_INWARDLY_RECTIFYING_K_CHANNELS

GABBR2 KCNJ8 KCNJ16

1.29e-0335873M1075
PathwayBIOCARTA_FLUMAZENIL_PATHWAY

GABRA1 GABRA2

1.32e-039872M22034
PathwayKEGG_MEDICUS_REFERENCE_BCR_PLCG_ITPR_SIGNALING_PATHWAY

ITPR2 ITPR3

1.32e-039872M47852
PathwayREACTOME_ESTROGEN_DEPENDENT_NUCLEAR_EVENTS_DOWNSTREAM_OF_ESR_MEMBRANE_SIGNALING

XPO1 AKT2

1.32e-039872MM15666
PathwaySIG_PIP3_SIGNALING_IN_B_LYMPHOCYTES

ITPR2 ITPR3 AKT2

1.40e-0336873M1315
PathwayREACTOME_INWARDLY_RECTIFYING_K_CHANNELS

GABBR2 KCNJ8 KCNJ16

1.40e-0336873MM14544
PathwayWP_MBDNF_AND_PROBDNF_REGULATION_OF_GABA_NEUROTRANSMISSION

GABRQ GABRA1 GABRA2

1.64e-0338873M39854
PathwayBIOCARTA_GABA_PATHWAY

GABRA1 GABRA2

1.64e-0310872M477
PathwayWP_STEROID_BIOSYNTHESIS

CYP17A1 CPN1

1.64e-0310872M39538
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SPTBN2_TO_MGLUR1_TRPC3_SIGNALING_PATHWAY

ITPR2 ITPR3

1.64e-0310872M47661
PathwayBIOCARTA_GABA_PATHWAY

GABRA1 GABRA2

1.64e-0310872MM1401
PathwayREACTOME_NEUROTRANSMITTER_RECEPTORS_AND_POSTSYNAPTIC_SIGNAL_TRANSMISSION

GABRQ GABBR2 KCNJ16 HTR3D GABRA1 GABRA2

1.67e-03205876M752
PathwayREACTOME_PARACETAMOL_ADME

UGT1A10 UGT1A8 UGT1A7

1.77e-0339873MM15695
PathwayREACTOME_TRANSMISSION_ACROSS_CHEMICAL_SYNAPSES

CACNA1E GABRQ GABBR2 KCNJ16 GABRA1 GABRA2

1.93e-03211876MM14502
PathwayREACTOME_NEUROTRANSMITTER_RECEPTORS_AND_POSTSYNAPTIC_SIGNAL_TRANSMISSION

GABRQ GABBR2 KCNJ16 GABRA1 GABRA2

1.96e-03144875MM14501
PathwayREACTOME_SODIUM_CALCIUM_EXCHANGERS

SLC8A2 SLC8A3

2.00e-0311872M27336
PathwayKEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_PRKCG_TO_MGLUR1_TRPC3_SIGNALING_PATHWAY

ITPR2 ITPR3

2.00e-0311872M49033
PathwayREACTOME_CLEC7A_DECTIN_1_INDUCES_NFAT_ACTIVATION

ITPR2 ITPR3

2.00e-0311872M27466
PathwayKEGG_PORPHYRIN_AND_CHLOROPHYLL_METABOLISM

UGT1A10 UGT1A8 UGT1A7

2.04e-0341873M7399
PathwayREACTOME_DAG_AND_IP3_SIGNALING

PDE1B ITPR2 ITPR3

2.04e-0341873M512
PathwayREACTOME_REDUCTION_OF_CYTOSOLIC_CA_LEVELS

SLC8A2 SLC8A3

2.39e-0312872M27326
PathwayWP_IRINOTECAN_PATHWAY

UGT1A10 BCHE

2.39e-0312872M39611
PathwayREACTOME_ASPIRIN_ADME

UGT1A8 UGT1A7 BCHE

2.50e-0344873M45014
PathwaySIG_CHEMOTAXIS

ITPR2 ITPR3 AKT2

2.67e-0345873M5193
PathwayREACTOME_SODIUM_CALCIUM_EXCHANGERS

SLC8A2 SLC8A3

2.81e-0313872MM15078
PathwayKEGG_MEDICUS_REFERENCE_MGLUR1_TRPC3_SIGNALING_PATHWAY

ITPR2 ITPR3

2.81e-0313872M47656
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_PSEN1_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY

ITPR2 ITPR3

2.81e-0313872M47696
PathwayKEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_SIGMAR1_TO_CA2_APOPTOTIC_PATHWAY

ITPR2 ITPR3

2.81e-0313872M47751
PathwaySIG_BCR_SIGNALING_PATHWAY

ITPR2 ITPR3 AKT2

2.85e-0346873M8626
Pubmed

Maternal Transient Receptor Potential Vanilloid 6 (Trpv6) Is Involved In Offspring Bone Development.

CACNA1E TRPC6 ITPR2 ITPR3 SLC8A2 SLC8A3

1.77e-0938106630786075
Pubmed

Mayo Genome Consortia: a genotype-phenotype resource for genome-wide association studies with an application to the analysis of circulating bilirubin levels.

UGT1A10 UGT1A8 UGT1A7 MROH2A

7.97e-0814106421646302
Pubmed

Multiple variable first exons: a mechanism for cell- and tissue-specific gene regulation.

UGT1A10 UGT1A8 UGT1A7 PLEC

7.97e-0814106414672974
Pubmed

Circadian Clock Component Rev-erbα Regulates Diurnal Rhythm of UDP-Glucuronosyltransferase 1a9 and Drug Glucuronidation in Mice.

UGT1A10 UGT1A8 UGT1A7

5.47e-076106332527940
Pubmed

Use of glucuronidation fingerprinting to describe and predict mono- and dihydroxyflavone metabolism by recombinant UGT isoforms and human intestinal and liver microsomes.

UGT1A10 UGT1A8 UGT1A7

5.47e-076106320297805
Pubmed

Assignment of the human UDP glucuronosyltransferase gene (UGT1A1) to chromosome region 2q37.

UGT1A10 UGT1A8 UGT1A7

9.55e-07710638467709
Pubmed

Molecular cloning of two cDNAs encoding the mouse bilirubin/phenol family of UDP-glucuronosyltransferases (mUGTBr/p).

UGT1A10 UGT1A8 UGT1A7

9.55e-07710638464825
Pubmed

theta, a novel gamma-aminobutyric acid type A receptor subunit.

GABRQ GABRA1 GABRA2

9.55e-077106310449790
Pubmed

Cyp3a11-mediated testosterone-6β-hydroxylation decreased, while UGT1a9-mediated propofol O-glucuronidation increased, in mice with diabetes mellitus.

UGT1A10 UGT1A8 UGT1A7

9.55e-077106327514509
Pubmed

Alternatively spliced products of the UGT1A gene interact with the enzymatically active proteins to inhibit glucuronosyltransferase activity in vitro.

UGT1A10 UGT1A8 UGT1A7

1.52e-068106320610558
Pubmed

Disposition of flavonoids via enteric recycling: enzyme stability affects characterization of prunetin glucuronidation across species, organs, and UGT isoforms.

UGT1A10 UGT1A8 UGT1A7

1.52e-068106318052087
Pubmed

Oligomerization of the UDP-glucuronosyltransferase 1A proteins: homo- and heterodimerization analysis by fluorescence resonance energy transfer and co-immunoprecipitation.

UGT1A10 UGT1A8 UGT1A7

1.52e-068106317179145
Pubmed

A genome-wide association study identifies UGT1A1 as a regulator of serum cell-free DNA in young adults: The Cardiovascular Risk in Young Finns Study.

UGT1A10 UGT1A8 UGT1A7

2.28e-069106322511988
Pubmed

Association of SNPs in the UGT1A gene cluster with total bilirubin and mortality in the Diabetes Heart Study.

UGT1A10 UGT1A8 UGT1A7

3.25e-0610106323642732
Pubmed

UDP-glucuronosyltransferases.

UGT1A10 UGT1A8 UGT1A7

3.25e-0610106311465080
Pubmed

A genome-wide association study for serum bilirubin levels and gene-environment interaction in a Chinese population.

UGT1A10 UGT1A8 UGT1A7

3.25e-0610106323371916
Pubmed

A genome-wide association study of total bilirubin and cholelithiasis risk in sickle cell anemia.

UGT1A10 UGT1A8 UGT1A7

3.25e-0610106322558097
Pubmed

Role of UDP-glucuronosyltransferase isoforms in 13-cis retinoic acid metabolism in humans.

UGT1A10 UGT1A8 UGT1A7

5.93e-0612106320308471
Pubmed

Common variants in the SLCO1B3 locus are associated with bilirubin levels and unconjugated hyperbilirubinemia.

UGT1A10 UGT1A8 UGT1A7

5.93e-0612106319419973
Pubmed

Thirteen UDPglucuronosyltransferase genes are encoded at the human UGT1 gene complex locus.

UGT1A10 UGT1A8 UGT1A7

5.93e-0612106311434514
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

PLXNA3 POLG PIEZO1 DOCK9 ICE1 FAM83H ITPR2 ITPR3 KCNK5 AKT2 DEPDC5 NLGN2 PLEC DOCK6

6.87e-0611051061435748872
Pubmed

UGT1A1 is a major locus influencing bilirubin levels in African Americans.

UGT1A10 UGT1A8 UGT1A7

7.70e-0613106322085899
Pubmed

Genome-wide analysis of hepatic lipid content in extreme obesity.

UGT1A10 UGT1A8 UGT1A7

7.70e-0613106325246029
Pubmed

Organization of the gene (RHCE) encoding the human blood group RhCcEe antigens and characterization of the promoter region.

RHCE RHD

9.20e-06210628188244
Pubmed

Preferential involvement of Na⁺/Ca²⁺ exchanger type-1 in the brain damage caused by transient focal cerebral ischemia in mice.

SLC8A2 SLC8A3

9.20e-062106223137542
Pubmed

Isoform diversity of the inositol trisphosphate receptor in cell types of mouse origin.

ITPR2 ITPR3

9.20e-06210629065779
Pubmed

DCS-1, DCS-2, and DFV share amino acid substitutions at the extracellular RhD protein vestibule.

RHCE RHD

9.20e-062106217900276
Pubmed

RHD and RHCE molecular analysis in weak D blood donors and in patients with Rh antibodies against their own corresponding Rh antigen.

RHCE RHD

9.20e-062106232697929
Pubmed

Na+/Ca2+ exchanger mediates cold Ca2+ signaling conserved for temperature-compensated circadian rhythms.

SLC8A2 SLC8A3

9.20e-062106233931447
Pubmed

Differential role of GABAA receptors and neuroligin 2 for perisomatic GABAergic synapse formation in the hippocampus.

NLGN2 GABRA1

9.20e-062106228643105
Pubmed

Review: the molecular basis of the Rh blood group phenotypes.

RHCE RHD

9.20e-062106215373666
Pubmed

Intron 4 of the RH Gene in Han Chinese, Tibetan, and Mongol Populations.

RHCE RHD

9.20e-062106226579938
Pubmed

Accurate long-read sequencing allows assembly of the duplicated RHD and RHCE genes harboring variants relevant to blood transfusion.

RHCE RHD

9.20e-062106234968422
Pubmed

Regarding the size of Rh proteins.

RHCE RHD

9.20e-06210621898705
Pubmed

α2-containing GABAA receptors expressed in hippocampal region CA3 control fast network oscillations.

GABRA1 GABRA2

9.20e-062106223109109
Pubmed

PCR screening for common weak D types shows different distributions in three Central European populations.

RHCE RHD

9.20e-062106211161244
Pubmed

Mechanosensitive cation currents through TRPC6 and Piezo1 channels in human pulmonary arterial endothelial cells.

PIEZO1 TRPC6

9.20e-062106235968892
Pubmed

RH diversity in Mali: characterization of a new haplotype RHD*DIVa/RHCE*ceTI(D2).

RHCE RHD

9.20e-062106225857637
Pubmed

Ca2+ regulation in the Na+/Ca2+ exchanger features a dual electrostatic switch mechanism.

SLC8A2 SLC8A3

9.20e-062106219667209
Pubmed

The low-prevalence Rh antigen STEM (RH49) is encoded by two different RHCE*ce818T alleles that are often in cis to RHD*DOL.

RHCE RHD

9.20e-062106222738288
Pubmed

Multiple Rh messenger RNA isoforms are produced by alternative splicing.

RHCE RHD

9.20e-06210621379850
Pubmed

Cloning and characterization of human type 2 and type 3 inositol 1,4,5-trisphosphate receptors.

ITPR2 ITPR3

9.20e-06210628081734
Pubmed

Characterization of the mouse Rh blood group gene.

RHCE RHD

9.20e-062106210329015
Pubmed

GAB(A) receptors present higher affinity and modified subunit composition in spinal motor neurons from a genetic model of amyotrophic lateral sclerosis.

GABRA1 GABRA2

9.20e-062106218973555
Pubmed

RHCE*ceMO is frequently in cis to RHD*DAU0 and encodes a hr(S) -, hr(B) -, RH:-61 phenotype in black persons: clinical significance.

RHCE RHD

9.20e-062106223772606
Pubmed

Studies on the substrate specificity of human intestinal UDP- lucuronosyltransferases 1A8 and 1A10.

UGT1A10 UGT1A8

9.20e-062106210497143
Pubmed

Determination of the N-terminal sequence of human red cell Rh(D) polypeptide and demonstration that the Rh(D), (c), and (E) antigens are carried by distinct polypeptide chains.

RHCE RHD

9.20e-06210623135863
Pubmed

Molecular cloning of mouse type 2 and type 3 inositol 1,4,5-trisphosphate receptors and identification of a novel type 2 receptor splice variant.

ITPR2 ITPR3

9.20e-062106215632133
Pubmed

Sequences and evolution of mammalian RH gene transcripts and proteins.

RHCE RHD

9.20e-06210629811965
Pubmed

Rare RHCE phenotypes in black individuals of Afro-Caribbean origin: identification and transfusion safety.

RHCE RHD

9.20e-062106212393640
Pubmed

Molecular genetic basis of the human Rhesus blood group system.

RHCE RHD

9.20e-06210628220426
Pubmed

Isolation of a new cDNA clone encoding an Rh polypeptide associated with the Rh blood group system.

RHCE RHD

9.20e-06210627916743
Pubmed

RHD*DOL1 and RHD*DOL2 encode a partial D antigen and are in cis with the rare RHCE*ceBI allele in people of African descent.

RHCE RHD

9.20e-062106222690701
Pubmed

No Distinction of Orthology/Paralogy between Human and Chimpanzee Rh Blood Group Genes.

RHCE RHD

9.20e-062106226872772
Pubmed

RHCE*ceTI encodes partial c and partial e and is often in cis to RHD*DIVa.

RHCE RHD

9.20e-062106222804620
Pubmed

Intricate combinatorial patterns of exon splicing generate multiple Rh-related isoforms in human erythroid cells.

RHCE RHD

9.20e-06210627789951
Pubmed

E variants found in Japanese and c antigenicity alteration without substitution in the second extracellular loop.

RHCE RHD

9.20e-062106211724987
Pubmed

Expression of IP3 receptor isoforms at the nodes of Ranvier in rat sciatic nerve.

ITPR2 ITPR3

9.20e-062106217496801
Pubmed

The Rh blood group system: a review.

RHCE RHD

9.20e-062106210627438
Pubmed

Polymorphisms in the promoter regions of RHD and RHCE genes in the Chinese Han population.

RHCE RHD

9.20e-062106237823181
Pubmed

Sequence diversity of the Rh blood group system in Basques.

RHCE RHD

9.20e-062106230089826
Pubmed

Mice lacking inositol 1,4,5-trisphosphate receptors exhibit dry eye.

ITPR2 ITPR3

9.20e-062106224901844
Pubmed

Consequences of prenatal exposure to diazepam on the respiratory parameters, respiratory network activity and gene expression of alpha1 and alpha2 subunits of GABA(A) receptor in newborn rat.

GABRA1 GABRA2

9.20e-062106218085262
Pubmed

Quantitative localisation of synaptic and extrasynaptic GABAA receptor subunits on hippocampal pyramidal cells by freeze-fracture replica immunolabelling.

GABRA1 GABRA2

9.20e-062106221073549
Pubmed

Adrenergic inhibition facilitates normalization of extracellular potassium after cortical spreading depolarization.

ITPR2 ITPR3

9.20e-062106233854148
Pubmed

Transfusion strategy for weak D Type 4.0 based on RHD alleles and RH haplotypes in Tunisia.

RHCE RHD

9.20e-062106229193104
Pubmed

Synapse formation and clustering of neuroligin-2 in the absence of GABAA receptors.

NLGN2 GABRA1

9.20e-062106218723687
Pubmed

Pancreatic protease activation by alcohol metabolite depends on Ca2+ release via acid store IP3 receptors.

ITPR2 ITPR3

9.20e-062106219528657
Pubmed

Determination of relative amounts of inositol trisphosphate receptor mRNA isoforms by ratio polymerase chain reaction.

ITPR2 ITPR3

9.20e-06210628063813
Pubmed

Glucuronidation: an important mechanism for detoxification of benzo[a]pyrene metabolites in aerodigestive tract tissues.

UGT1A10 UGT1A8

9.20e-062106211901093
Pubmed

RHCE variants inherited with altered RHD alleles in Brazilian blood donors.

RHCE RHD

9.20e-062106227111588
Pubmed

Alteration of RH gene structure and expression in human dCCee and DCW-red blood cells: phenotypic homozygosity versus genotypic heterozygosity.

RHCE RHD

9.20e-06210628822955
Pubmed

Genetic recombination at the human RH locus: a family study of the red-cell Evans phenotype reveals a transfer of exons 2-6 from the RHD to the RHCE gene.

RHCE RHD

9.20e-06210628808597
Pubmed

Molecular background of Rh D-positive, D-negative, D(el) and weak D phenotypes in Chinese.

RHCE RHD

9.20e-062106212201845
Pubmed

Variant RH alleles and Rh immunisation in patients with sickle cell disease.

RHCE RHD

9.20e-062106224960646
Pubmed

Testing the silence of mutations: Transcriptomic and behavioral studies of GABA(A) receptor α1 and α2 subunit knock-in mice.

GABRA1 GABRA2

9.20e-062106221056629
Pubmed

IP3 receptor types 2 and 3 mediate exocrine secretion underlying energy metabolism.

ITPR2 ITPR3

9.20e-062106216195467
Pubmed

Comprehensive phenotypic and molecular investigation of RhD and RhCE variants in Moroccan blood donors.

RHCE RHD

9.20e-062106230418133
Pubmed

A convenient qualitative and quantitative method to investigate RHD-RHCE hybrid genes.

RHCE RHD

9.20e-062106223550903
Pubmed

Molecular cloning and primary structure of the human blood group RhD polypeptide.

RHCE RHD

9.20e-06210621438298
Pubmed

Human UGT1A8 and UGT1A10 mRNA are expressed in primary human hepatocytes.

UGT1A10 UGT1A8

9.20e-062106217603215
Pubmed

Molecular background of D(C)(e) haplotypes within the white population.

RHCE RHD

9.20e-062106212084172
Pubmed

Inositol (1,4,5)-trisphosphate receptor links to filamentous actin are important for generating local Ca2+ signals in pancreatic acinar cells.

ITPR2 ITPR3

9.20e-062106215713744
Pubmed

The analysis of nucleotide substitutions, gaps, and recombination events between RHD and RHCE genes through complete sequencing.

RHCE RHD

9.20e-062106210924335
Pubmed

A two-locus gene conversion model with selection and its application to the human RHCE and RHD genes.

RHCE RHD

9.20e-062106212857961
Pubmed

Specific amino acid substitutions cause distinct expression of JAL (RH48) and JAHK (RH53) antigens in RhCE and not in RhD.

RHCE RHD

9.20e-062106220233350
Pubmed

A recombination hot spot in the Rh genes revealed by analysis of unrelated donors with the rare D-- phenotype.

RHCE RHD

9.20e-06210628900235
Pubmed

Characterization of two UDP glucuronosyltransferases that are predominantly expressed in human colon.

UGT1A10 UGT1A8

9.20e-06210629647757
Pubmed

The role of the mitochondrial NCX in the mechanism of neurodegeneration in Parkinson's disease.

SLC8A2 SLC8A3

9.20e-062106223224884
Pubmed

RHD*weak partial 4.0 is associated with an altered RHCE*ce(48C, 105T, 733G, 744C, 1025T) allele in the Tunisian population.

RHCE RHD

9.20e-062106223742316
Pubmed

A comprehensive survey of both RHD and RHCE allele frequencies in sub-Saharan Africa.

RHCE RHD

9.20e-062106224033223
Pubmed

DDX19 Inhibits Type I Interferon Production by Disrupting TBK1-IKKε-IRF3 Interactions and Promoting TBK1 and IKKε Degradation.

DDX19B DDX19A

9.20e-062106230699353
Pubmed

Human UDP-glucuronosyltransferases: metabolism, expression, and disease.

UGT1A10 UGT1A8 UGT1A7

9.77e-0614106310836148
Pubmed

The UDP glycosyltransferase gene superfamily: recommended nomenclature update based on evolutionary divergence.

UGT1A10 UGT1A8 UGT1A7

9.77e-061410639295054
Pubmed

Identification of an evolutionarily conserved superfamily of DOCK180-related proteins with guanine nucleotide exchange activity.

DOCK9 DOCK10 DOCK6

9.77e-0614106312432077
Pubmed

Why do cellular proteins linked to K63-polyubiquitin chains not associate with proteasomes?

SGK1 DNASE2B KLHL13 THG1L DOCK6 UNC79

1.42e-05170106623314748
Pubmed

Genome-wide association meta-analysis for total serum bilirubin levels.

UGT1A10 UGT1A8 UGT1A7

1.50e-0516106319414484
Pubmed

Genome-wide association of serum bilirubin levels in Korean population.

UGT1A10 UGT1A8 UGT1A7

1.81e-0517106320639394
Pubmed

Ecm29-mediated proteasomal distribution modulates excitatory GABA responses in the developing brain.

NLGN2 GABRA1 GABRA2

2.17e-0518106331910261
Pubmed

Strong genetic evidence for a selective influence of GABAA receptors on a component of the bipolar disorder phenotype.

GABRQ GABRA1 GABRA2

2.17e-0518106319078961
Cytoband2q37

UGT1A10 UGT1A8 UGT1A7

5.13e-053110632q37
GeneFamilyInositol 1,4,5-triphosphate receptors|Protein phosphatase 1 regulatory subunits

ITPR2 ITPR3

5.08e-053752297
GeneFamilyGamma-aminobutyric acid type A receptor subunits

GABRQ GABRA1 GABRA2

6.33e-0519753563
GeneFamilyUDP glucuronosyltransferases

UGT1A10 UGT1A8 UGT1A7

3.12e-0432753363
GeneFamilyPotassium voltage-gated channel subfamily J

KCNJ8 KCNJ16

1.96e-0316752276
ToppCellfacs-Mammary_Gland-Mammary_Gland-18m-Epithelial-luminal_progenitor_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLB1 PIEZO1 SLC28A3 ITPR2 KCNK5 AFDN

6.11e-06189106627e5d706f10a6221f314faf642eede15deab3165
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

LGR4 ITPR3 PPP2R3A KLHL13 AFDN DNAH5

6.89e-061931066f42a0f02ed00fe1bb833ff0a0640d9131bca89bd
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

LGR4 ITPR3 PPP2R3A KLHL13 AFDN DNAH5

6.89e-06193106642df7ed37d11fb542b4d1d714b6f87ae8e1396a6
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NAPEPLD LGR4 SLC9C1 PPP2R3A KCNJ16 AFDN

7.52e-061961066c7136b1c83bcf907eec3b02b151fa061298b6672
ToppCellBAL-Severe-Myeloid-cDC-cDC-cDC_6|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

TRPC6 BIRC3 RECQL5 PRMT9 UNC79

3.59e-0515610650f2147abcf31a26ee5b2f4d8c5d72232612a33f0
ToppCellBAL-Severe-Myeloid-cDC-cDC-cDC_6|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TRPC6 BIRC3 RECQL5 PRMT9 UNC79

3.59e-051561065cb87f12443fdc5538b856f765fcbac9406044e10
ToppCellfacs-Lung-nan-3m-Myeloid-myeloid_dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NUP210L TLR9 M1AP RECQL5 THG1L

4.83e-0516610655c132f505dc5f699c87913f140344fc9f8e7e0f5
ToppCellmild-Others-CD34+_GATA2+_cells|mild / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

MEIS1 SLC9C1 SLC8A3 KLHL13 ALDH3B2

5.71e-051721065379f6f271e653d5e404851e51a189bd582bb0f43
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_FAM95C|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TRPC6 BIRC3 MEIS3 SLC8A2 KCNJ8

6.72e-051781065431e7557b8e8764e16e9e48368ce6bfa3c61561a
ToppCellChildren_(3_yrs)-Epithelial-basal_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

ST6GALNAC1 TRPC6 LGR4 KLHL13 DNAH5

6.72e-051781065fba2e38c05cbf031e0c6d47b1602575fea734a57
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_FAM95C|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TRPC6 BIRC3 MEIS3 SLC8A2 KCNJ8

7.09e-051801065b514c55e52b46e8a1a2f09ed2c59a7683367a505
ToppCellCOVID-19-kidney-tDL|COVID-19 / Disease (COVID-19 only), tissue and cell type

CACNA1E PPP2R3A KLHL13 KCNJ16 KCNK5

7.09e-051801065864c895b5eaedefae86f5829fa344f7b686fb59f
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ARFGEF1 LGR4 ITPR3 KLHL13 KCNJ16

7.27e-05181106522363c5835dd6cef8f895ab9362e0837d92b15b1
ToppCellfacs-Heart-LV-18m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DDX19B SETX PIEZO1 KMO THG1L

7.47e-0518210656dff753d65ba45db81f3cc0c9f59e1779d490955
ToppCellFetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

NR2E3 BCHE MEIS3 MEIS1 OSMR

7.47e-051821065ed6ae0fd8653f213fe29906a6a4e0729a62e1b75
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DYNC2H1 MAP4K3 LGR4 KCNJ16 GABRA2

7.66e-0518310652f0ee40e69ad1259e56e8ee4b352736900eb8901
ToppCell5'-Airway_Nasal-Immune_Myeloid-Dendritic-dendritic_cell-Migratory_DCs|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DOCK10 BIRC3 KMO THG1L RSPH10B

8.27e-051861065a558fd00053e7dd6216b01dc8e650c30cee451f1
ToppCell5'-Airway_Nasal-Immune_Myeloid-Dendritic-dendritic_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DOCK10 BIRC3 KMO THG1L RSPH10B

8.27e-05186106575b1f342be5d6dbe0e7acd924a0ca75964f6bab0
ToppCell5'-Airway_Nasal-Immune_Myeloid-Dendritic-dendritic_cell-Migratory_DCs-|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DOCK10 BIRC3 KMO THG1L RSPH10B

8.27e-0518610650c3d195077de7b4c354c127a26116438aef29244
ToppCellCV-Moderate-7|CV / Virus stimulation, Condition and Cluster

MMS22L NAPEPLD DOCK10 XPO1 ITPR2

8.27e-0518610658571956890fc9894d766ba294a28e376b4aba428
ToppCellCOVID-19-kidney-Mito-rich_Distal|kidney / Disease (COVID-19 only), tissue and cell type

LGR4 PPP2R3A KLHL13 KCNJ16 DNAH5

8.48e-0518710652ce8038d9d1302e850c1bb536e755598f77ba4b9
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CAPN14 DYNC2H1 LGR4 KLHL13 KCNJ16

8.48e-051871065f124d2c699b717b7c02a1a70493f515b83dc2f4c
ToppCellCOVID-19-kidney-DCT|kidney / Disease (COVID-19 only), tissue and cell type

MMS22L DYNC2H1 LGR4 KLHL13 KCNJ16

8.70e-051881065df1fd0819d301679f3c9ea404e942e39095912eb
ToppCellCOVID-19-kidney-DCT|COVID-19 / Disease (COVID-19 only), tissue and cell type

DYNC2H1 LGR4 PPP2R3A KLHL13 KCNJ16

8.70e-0518810651d56cd409793f05cca20757ab26e91f1a1ee67b5
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LGR4 BIRC3 ITPR3 KLHL13 DNAH5

8.92e-051891065aadb7a2de4cbe7f0958651f2739bba430b93f5c1
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CAPN14 DYNC2H1 LGR4 KLHL13 KCNJ16

8.92e-051891065e32172ad09e93f6ac6ea2b92145b2b73003f7970
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LGR4 BIRC3 ITPR3 KLHL13 DNAH5

8.92e-0518910658977f3295b7df7c7474b3f371de90a82ae4bb50c
ToppCell10x5'v1-week_12-13-Endothelial-stroma-tip_EC|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

COL15A1 DOCK9 BCHE KCNJ8 DOCK6

9.37e-051911065cf1a67b7c0d5c0dc5d4d59faf9d9b1a3a1fb00e0
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LGR4 PPP2R3A KLHL13 KCNJ16 DNAH5

9.37e-0519110659032aa974aa1b7b1095b8d1b58dcb087358a5001
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LGR4 PPP2R3A KLHL13 KCNJ16 DNAH5

9.37e-0519110655717809a1476c20f65bce722c5a57cff92ee0d7a
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LGR4 ITPR3 KLHL13 KCNJ16 DNAH5

9.84e-051931065263d185af6ed80e639f864e4966268e0862c61dc
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LGR4 ITPR3 KLHL13 KCNJ16 DNAH5

9.84e-05193106580e058c224749b5fe0ba3e944b48317c2371cb63
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LGR4 ITPR3 KLHL13 KCNJ16 DNAH5

9.84e-051931065b991fbbb4618401624f0b3045f0e81a606d3a763
ToppCellfacs-Mammary_Gland-Mammary_Gland-18m-Epithelial-luminal_epithelial_cell_of_mammary_gland|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLB1 SLC28A3 ITPR2 KCNK5 AFDN

9.84e-0519310651526f51b589a7dc7a28f35f0e788dc38d338d2bc
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

LGR4 ITPR3 KLHL13 AFDN DNAH5

1.01e-041941065e577d9e88390b36b5a09b97fe1026089892275a3
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

TRPC6 DOCK10 MEIS1 SLC8A3 GLCE

1.03e-0419510650e55fa5b3cbeb7baee3d4ac272a3bf80381ec937
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

LGR4 PPP2R3A KLHL13 KCNJ16 AFDN

1.03e-0419510656477e6e7be5bd8eb99119a12ae16334ccddecd43
ToppCellfacs-Thymus-Thymus_Epithelium|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL15A1 MROH2A LGR4 OSMR DNAH5

1.06e-0419610656bc1187dfc4860a4e09032d7ea87ba3d9fe9f363
ToppCellfacs-Thymus-Thymus_Epithelium-18m|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL15A1 MROH2A LGR4 OSMR DNAH5

1.06e-041961065c8c89e469402e11aa2a9561e859b6fd1fb66c39b
ToppCellCOVID-19-kidney-TAL|kidney / Disease (COVID-19 only), tissue and cell type

LGR4 ITPR3 KLHL13 KCNJ16 DNAH5

1.06e-04196106504f5eb206ed3016a737609a3ebac0c1fcabb94ef
ToppCelldroplet-Mammary_Gland-nan-3m-Epithelial-luminal_progenitor_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLB1 PIEZO1 SLC28A3 FAM83H KCNK5

1.06e-04196106522fcfb713f402ebbd43b2822f0fd919cdbfba6e4
ToppCellBasal_cells-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

ST6GALNAC1 UGT1A10 UGT1A7 TRPC6 LGR4

1.06e-0419610653b66f3a79b3f2ebacb4ad646f179e505ab38d6f0
ToppCellLung_Parenchyma-Control-Myeloid-Mast_cell|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

SGK1 BIRC3 SLC8A3 PRMT9 TTI1

1.11e-0419810650af55f2b859e4626e23e2733bf9ae2ace4547079
ToppCellLung_Parenchyma-Control-Myeloid-Mast_cell-Mast_cells-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SGK1 BIRC3 SLC8A3 PRMT9 TTI1

1.11e-041981065f75800b4f3cf0d493226db8db7c949caade0ff90
ToppCell10x5'v1-week_12-13-Endothelial-stroma|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

COL15A1 DOCK9 BCHE KCNJ8 DOCK6

1.11e-041981065122215d9288533ad03562cf777e846504863df9a
ToppCellParenchyma_Control_(B.)-Immune-TX-Mast_cells|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

SGK1 BIRC3 SLC8A3 PRMT9 TTI1

1.11e-04198106545089e0adf2c00f4b0bccd701f4daebf25858006
ToppCell10x5'v1-week_12-13-Endothelial|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

COL15A1 DOCK9 BCHE KCNJ8 DOCK6

1.11e-041981065307dd09e6bc820a148f3000f18dae7aedba4be0b
ToppCellLung_Parenchyma-Control-Myeloid-Mast_cell-Mast_cells|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

SGK1 BIRC3 SLC8A3 PRMT9 TTI1

1.11e-0419810654163220f4ccb825a8399298cfac8411eb2acc9a2
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia_independent-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PLXNA3 PIEZO1 ITPR3 PLEC OSMR

1.14e-04199106585bb28369e0568b7b3bda095722102fc793f60ef
ToppCellLPS_IL1RA-Endothelial-Endothelial-Gen_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

SETX ATRX DOCK9 AFDN DOCK6

1.16e-042001065dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCellControl_saline-Endothelial-Endothelial|Control_saline / Treatment groups by lineage, cell group, cell type

SETX DOCK9 AFDN PLEC DOCK6

1.16e-042001065e77eba6172cabf85b8028638ed35299f2f079cd8
ToppCellLPS_anti-TNF-Endothelial-Endothelial-Gen_Cap|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

SETX ATRX DOCK9 AFDN DOCK6

1.16e-042001065a2b9d1cd291d17abddc3ee2e242121412c864b8b
ToppCellControl_saline-Endothelial|Control_saline / Treatment groups by lineage, cell group, cell type

SETX DOCK9 AFDN PLEC DOCK6

1.16e-0420010653372c488a39fe812fa94e4f0564594186fea3db5
DrugFinrazole

UGT1A10 UGT1A8 UGT1A7 GABRQ PROZ GABRA1 GABRA2

3.32e-09511047CID000178036
Drugprazepam

GABRQ GABBR2 PROZ GABRA1 GABRA2

3.46e-08211045CID000004890
DrugP4-s

DDX19B GABRQ GABBR2 GABRA1 GABRA2

8.92e-08251045CID000004838
Drughexobarbital

UGT1A10 UGT1A8 UGT1A7 CYP17A1 GABRQ GABBR2 GABRA1 GABRA2

1.23e-071271048CID000003608
DrugDehydroisoandosterone 3-acetate [853-23-6]; Up 200; 12.2uM; MCF7; HT_HG-U133A

NR2E3 SGK1 BIRC3 COLGALT2 KMO ITPR2 KCNK5 AKT2 HERC5

2.06e-0718810495019_UP
Drugalpha IMGBL

GABRQ GABBR2 GABRA1 GABRA2

2.85e-07131044CID000131516
Drug3-aminopropylphosphinic acid

CACNA1E GABRQ GABBR2 GABRA1 GABRA2

3.29e-07321045CID006335948
Drughydratropic acid

UGT1A10 UGT1A8 UGT1A7

3.69e-0741043ctd:C013025
Drug2-vanillin

UGT1A10 UGT1A8 UGT1A7

3.69e-0741043ctd:C060843
Drugdiphenylacetic acid

UGT1A10 UGT1A8 UGT1A7

3.69e-0741043ctd:C037760
Drugpinazepam

GABRQ PROZ GABRA1 GABRA2

5.39e-07151044CID000040391
Drugnaringenin chalcone

UGT1A10 UGT1A8 UGT1A7

9.20e-0751043ctd:C027329
Drugisovaleric acid

UGT1A10 UGT1A8 UGT1A7

9.20e-0751043ctd:C008216
Druganthrarobin

UGT1A10 UGT1A8 UGT1A7

9.20e-0751043ctd:C032186
Drugbiphenylylacetic acid

UGT1A10 UGT1A8 UGT1A7

9.20e-0751043ctd:C012776
Druggabapentin

CACNA1E ACO1 GABRQ GABBR2 MEIS1 ITPR3 GABRA1 GABRA2

1.10e-061691048CID000003446
Drugclorazepate

GABRQ GABBR2 GABRA1 GABRA2

1.20e-06181044CID000002809
Drugphenazepam

GABRQ PROZ GABRA1 GABRA2

1.20e-06181044CID000040113
DrugZK 93426

GABRQ GABBR2 GABRA1 GABRA2

1.51e-06191044CID000115210
Drug1,2,5,8-tetrahydroxy anthraquinone

UGT1A10 UGT1A8 UGT1A7

1.83e-0661043ctd:C543211
Drugalloin

UGT1A10 UGT1A8 UGT1A7

1.83e-0661043ctd:C006457
Drug3-phenylpropionic acid

UGT1A10 UGT1A8 UGT1A7

1.83e-0661043ctd:C035253
DrugIndoprofen

UGT1A10 UGT1A8 UGT1A7

1.83e-0661043ctd:D007216
Drug2',5'-dihydroxychalcone

UGT1A10 UGT1A8 UGT1A7

1.83e-0661043ctd:C107497
Drughalazepam

GABRQ PROZ GABRA1 GABRA2

1.88e-06201044CID000031640
DrugEBOB

GABRQ GABBR2 GABRA1 GABRA2

1.88e-06201044CID000115223
Drugbicuculline methochloride

GABRQ GABBR2 GABRA1 GABRA2

2.32e-06211044CID000123659
DrugR 5135

GABRQ GABBR2 GABRA1 GABRA2

2.32e-06211044CID000119544
Drugnitrazepam

GABRQ BCHE GABBR2 GABRA1 GABRA2

2.38e-06471045CID000004506
Drugpropofol

UGT1A10 UGT1A8 UGT1A7 GABRQ GABBR2 LCT GABRA1 GABRA2

2.74e-061911048CID000004943
Drugimidazenil

GABRQ GABBR2 GABRA1 GABRA2

2.82e-06221044CID000119194
Drugthiamylal

GABRQ GABBR2 KCNJ8 GABRA1 GABRA2

2.93e-06491045CID003032285
Drug2',4'-dihydroxychalcone

UGT1A10 UGT1A8 UGT1A7

3.20e-0671043ctd:C059354
Drugzolazepam

GABRQ GABBR2 GABRA1 GABRA2

3.40e-06231044CID000035775
DrugSuprofen [40828-46-4]; Down 200; 15.4uM; HL60; HT_HG-U133A

CYP17A1 DOCK9 ITPR3 RECQL5 AFDN PLEC RWDD2A DOCK6

3.45e-0619710483005_DN
Druggamma-acetylenic GABA

GABRQ GABBR2 GABRA1 GABRA2

4.07e-06241044CID000003452
Drugcinnamic acid

UGT1A10 UGT1A8 UGT1A7 CYP17A1

4.07e-06241044ctd:C029010
Drugmedazepam

GABRQ GABBR2 GABRA1 GABRA2

4.07e-06241044CID000004041
DrugSL 75102

GABRQ GABBR2 GABRA1 GABRA2

4.07e-06241044CID005751746
Drugisonipecotic acid

GABRQ GABBR2 GABRA1 GABRA2

4.83e-06251044CID000003773
Drug5,6-benzoquinoline

UGT1A10 UGT1A8 UGT1A7 BCHE

4.83e-06251044CID000006796
Drugbeta-CCE

GABRQ GABBR2 GABRA1 GABRA2

4.83e-06251044CID000105078
Drug1,4-dihydroxyanthraquinone

UGT1A10 UGT1A8 UGT1A7

5.10e-0681043ctd:C034890
DrugSKF97541

GABRQ GABBR2 GABRA1 GABRA2

5.68e-06261044CID000005230
DrugV-X-A

GABRQ GABBR2 GABRA1 GABRA2

5.68e-06261044CID006369389
DrugThymol

UGT1A10 UGT1A8 UGT1A7 GABRA1

5.68e-06261044ctd:D013943
Drugpitrazepin

GABRQ GABBR2 GABRA1 GABRA2

6.65e-06271044CID000146222
Druglindane

CACNA1E PLB1 GABRQ GABBR2 ITPR3 GABRA1 GABRA2

6.93e-061541047CID000000727
DrugAC1MRQNQ

UGT1A10 UGT1A8 UGT1A7

7.62e-0691043CID003522271
DrugDHPASiU

UGT1A10 UGT1A8 UGT1A7

7.62e-0691043CID000197602
Drug3-iodophenol

UGT1A10 UGT1A8 UGT1A7

7.62e-0691043CID000012272
DrugAC1L4J7U

UGT1A10 UGT1A8 UGT1A7

7.62e-0691043CID000186631
DrugChebi:32663

UGT1A10 UGT1A8 UGT1A7

7.62e-0691043CID005460873
DrugCARMINE

UGT1A10 UGT1A8 UGT1A7 LCT

7.73e-06281044CID000014749
Drugchlormethiazole

GABRQ GABBR2 GABRA1 GABRA2

7.73e-06281044CID000010783
Drugmephobarbital

GABRQ GABBR2 GABRA1 GABRA2

7.73e-06281044CID000008271
Drug5 beta-pregnanediol

CYP17A1 GABRQ BCHE GABRA1 GABRA2

8.07e-06601045CID000012547
Drug3-OH

UGT1A10 UGT1A8 UGT1A7 KMO RHD

8.76e-06611045CID000068152
Drugetazolate

GABRQ GABBR2 GABRA1 GABRA2

8.94e-06291044CID000003277
DrugCGP 35348

GABRQ GABBR2 KMO GABRA1 GABRA2

9.50e-06621045CID000107699
Drugvalproate

CACNA1E UGT1A10 UGT1A8 UGT1A7 POLG GABRQ GABBR2 ITPR3 GABRA1 GABRA2

9.88e-0638110410CID000003121
Drugguvacine

GABRQ GABBR2 GABRA1 GABRA2

1.03e-05301044CID000003532
Drugallylglycine

GABRQ GABBR2 GABRA1 GABRA2

1.03e-05301044CID000014044
DrugGlucuronides

UGT1A10 UGT1A8 LCT

1.09e-05101043ctd:D020719
Drug2,6-dihydroxyanthraquinone

UGT1A10 UGT1A8 UGT1A7

1.09e-05101043ctd:C034889
DrugAC1L1J7N

CYP17A1 GABRQ GABBR2 GABRA1 GABRA2

1.11e-05641045CID000004902
Drugnordiazepam

GABRQ GABBR2 PROZ GABRA1 GABRA2

1.11e-05641045CID000002997
DrugSKF89976A

GABRQ GABBR2 GABRA1 GABRA2

1.18e-05311044CID000092409
DrugNNAL

UGT1A10 UGT1A8 UGT1A7 PLEC

1.34e-05321044CID000104856
Drughomotaurine

GABRQ GABBR2 GABRA1 GABRA2

1.34e-05321044CID000001646
Drug3 -hydroxypregn-5-en-20-one

UGT1A10 UGT1A8 UGT1A7 CYP17A1 GABRQ PLEC GABRA1 GABRA2

1.38e-052381048CID000001027
Drugfosazepam

GABRQ GABRA1 GABRA2

1.49e-05111043CID000037114
DrugC19H18ClN3O

GABRQ GABRA1 GABRA2

1.49e-05111043CID000027452
Drugflutoprazepam

GABRQ GABRA1 GABRA2

1.49e-05111043CID000003400
DrugArfendazam

GABRQ GABRA1 GABRA2

1.49e-05111043CID000065803
Drugcamazepam

GABRQ GABRA1 GABRA2

1.49e-05111043CID000037367
DrugBu-1014

GABRQ GABRA1 GABRA2

1.49e-05111043CID015942721
DrugVanillic Acid

UGT1A10 UGT1A8 UGT1A7

1.49e-05111043ctd:D014641
DrugZapizolam

GABRQ GABRA1 GABRA2

1.49e-05111043CID000068832
DrugReclazepam

GABRQ GABRA1 GABRA2

1.49e-05111043CID003052777
Drugiclazepam

GABRQ GABRA1 GABRA2

1.49e-05111043CID000068777
Drugmenitrazepam

GABRQ GABRA1 GABRA2

1.49e-05111043CID000189875
Drug4-nitrophenyl)imidazole

UGT1A10 UGT1A8 UGT1A7

1.49e-05111043CID000123155
DrugSerin hydrazid

GABRQ GABRA1 GABRA2

1.49e-05111043CID000041637
DrugAC1O5XMV

UGT1A10 UGT1A8 UGT1A7

1.49e-05111043CID006442661
Drugsulazepam

GABRQ GABRA1 GABRA2

1.49e-05111043CID000017931
Drugelfazepam

GABRQ GABRA1 GABRA2

1.49e-05111043CID000065445
Drugtriflubazam

GABRQ GABRA1 GABRA2

1.49e-05111043CID000031157
Druguldazepam

GABRQ GABRA1 GABRA2

1.49e-05111043CID000034274
Druggidazepam

GABRQ GABRA1 GABRA2

1.49e-05111043CID000121919
Drugfletazepam

GABRQ GABRA1 GABRA2

1.49e-05111043CID000036834
DrugCGS 8216

GABRQ GABBR2 GABRA1 GABRA2

1.52e-05331044CID000104916
DrugAC1L2FYN

GABRQ GABBR2 GABRA1 GABRA2

1.52e-05331044CID000071333
Drugriluzole

CACNA1E GABRQ GABBR2 ITPR3 KCNK5 GABRA1 GABRA2

1.54e-051741047CID000005070
Druglamotrigine

CACNA1E UGT1A10 UGT1A8 UGT1A7 ITPR3 GABRA1

1.55e-051161046CID000003878
Drugamobarbital

GABRQ GABBR2 GABRA1 GABRA2

1.71e-05341044CID000002163
Drugtemazepam

GABRQ GABBR2 GABRA1 GABRA2

1.71e-05341044CID000005391
Drugestazolam

GABRQ GABBR2 GABRA1 GABRA2

1.93e-05351044CID000003261
Drugflurazepam

GABRQ GABBR2 GABRA1 GABRA2

1.93e-05351044CID000003393
Drug3-[(3S,5R,10S,13R,14S,17R)-3-[(2S,4R,5R,6S)-4,5-dihydroxy-6-methyloxan-2-yl]oxy-14-hydroxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]-2H-furan-5-one

UGT1A10 UGT1A8 UGT1A7 PLEC

1.93e-05351044CID010436171
Diseaseinsomnia, bilirubin measurement

UGT1A10 UGT1A8 UGT1A7 MROH2A

4.53e-08111034EFO_0004570, EFO_0004698
DiseaseN-acetyl-4-chlorophenylalanine measurement

UGT1A10 UGT1A8 UGT1A7

4.11e-0751033EFO_0801060
Disease5-hydroxyindole sulfate measurement

UGT1A10 UGT1A8 UGT1A7

4.11e-0751033EFO_0800085
Diseasenuclear receptor subfamily 1 group D member 2 measurement

UGT1A10 UGT1A8 UGT1A7

4.11e-0751033EFO_0801853
DiseaseX-21339 measurement

UGT1A10 UGT1A8 UGT1A7

1.43e-0671033EFO_0800808
DiseaseX-11793--oxidized bilirubin measurement

UGT1A10 UGT1A8 UGT1A7

2.28e-0681033EFO_0021260
DiseaseSuccinimide measurement

UGT1A10 UGT1A8 UGT1A7

2.28e-0681033EFO_0022118
DiseaseX-11530 measurement

UGT1A10 UGT1A8 UGT1A7

2.28e-0681033EFO_0021249
Diseasesulfate of piperine metabolite C16H19NO3 (2) measurement

UGT1A10 UGT1A8 UGT1A7

2.28e-0681033EFO_0801034
Diseasecholelithiasis, bilirubin measurement

UGT1A10 UGT1A8 UGT1A7

2.28e-0681033EFO_0004570, EFO_0004799
DiseaseX-11522 measurement

UGT1A10 UGT1A8 UGT1A7

2.28e-0681033EFO_0800696
DiseaseX-10458 measurement

UGT1A10 UGT1A8 UGT1A7

2.28e-0681033EFO_0800692
DiseaseX-24849 measurement

UGT1A10 UGT1A8 UGT1A7

2.28e-0681033EFO_0800909
Diseaseserum N-desmethylclozapine measurement

UGT1A10 UGT1A8 UGT1A7

2.28e-0681033EFO_0600043
Diseaseplasma clozapine measurement

UGT1A10 UGT1A8 UGT1A7

2.28e-0681033EFO_0600038
Diseasemembrane-associated progesterone receptor component 1 measurement

UGT1A10 UGT1A8 UGT1A7

2.28e-0681033EFO_0802740
DiseaseX-16946 measurement

UGT1A10 UGT1A8 UGT1A7

2.28e-0681033EFO_0800766
DiseaseX-11442 measurement

UGT1A10 UGT1A8 UGT1A7

3.42e-0691033EFO_0021236
DiseaseX-11441 measurement

UGT1A10 UGT1A8 UGT1A7

3.42e-0691033EFO_0021235
Diseasecirculating cell free DNA measurement

UGT1A10 UGT1A8 UGT1A7

3.42e-0691033EFO_0004739
Diseasesulfate of piperine metabolite C18H21NO3 (3) measurement

UGT1A10 UGT1A8 UGT1A7

3.42e-0691033EFO_0801037
Diseasesulfate of piperine metabolite C18H21NO3 (1) measurement

UGT1A10 UGT1A8 UGT1A7

3.42e-0691033EFO_0801036
DiseaseX-11880 measurement

UGT1A10 UGT1A8 UGT1A7

3.42e-0691033EFO_0800698
Diseaseprotein-tyrosine kinase 6 measurement

UGT1A10 UGT1A8 UGT1A7

3.42e-0691033EFO_0020691
Diseasetestis-specific chromodomain protein Y 1 measurement

UGT1A10 UGT1A8 UGT1A7

3.42e-0691033EFO_0802127
Diseasebilirubin measurement, response to xenobiotic stimulus

UGT1A10 UGT1A8 UGT1A7

3.42e-0691033EFO_0004570, GO_0009410
Diseasebilirubin measurement, response to tenofovir

UGT1A10 UGT1A8 UGT1A7

4.87e-06101033EFO_0004570, EFO_0009279
DiseaseX-21448 measurement

UGT1A10 UGT1A8 UGT1A7

4.87e-06101033EFO_0800816
DiseaseUDP-glucuronosyltransferase 1-6 measurement

UGT1A10 UGT1A8 UGT1A7

4.87e-06101033EFO_0802185
DiseaseX-23974 measurement

UGT1A10 UGT1A8 UGT1A7

4.87e-06101033EFO_0800867
Diseasepregnenetriol sulfate measurement

UGT1A10 UGT1A8 UGT1A7

6.68e-06111033EFO_0800586
Diseaseplasma N-desmethylclozapine measurement

UGT1A10 UGT1A8 UGT1A7

6.68e-06111033EFO_0600039
Diseasehistidine betaine (hercynine) measurement

UGT1A10 UGT1A8 UGT1A7

6.68e-06111033EFO_0800972
DiseaseX-21796 measurement

UGT1A10 UGT1A8 UGT1A7

6.68e-06111033EFO_0800825
Diseasealdosterone measurement

UGT1A10 UGT1A8 UGT1A7

6.68e-06111033EFO_0010219
Diseasep-cresol glucuronide measurement

UGT1A10 UGT1A8 UGT1A7

8.88e-06121033EFO_0800079
Diseasebiliverdin measurement

UGT1A10 UGT1A8 UGT1A7

8.88e-06121033EFO_0021033
Diseasepregnenetriol disulfate measurement

UGT1A10 UGT1A8 UGT1A7

1.15e-05131033EFO_0800587
Diseaseretinol dehydrogenase 16 measurement

UGT1A10 UGT1A8 UGT1A7

1.15e-05131033EFO_0802007
DiseaseAnemia, Hemolytic, Congenital

RHCE RHD

1.21e-0521032C0002881
Diseaselow density lipoprotein cholesterol measurement, body fat percentage

UGT1A10 UGT1A8 UGT1A7

2.71e-05171033EFO_0004611, EFO_0007800
DiseaseX-21441 measurement

UGT1A10 UGT1A8 UGT1A7

2.71e-05171033EFO_0800814
Diseaseangiopoietin-related protein 1 measurement

UGT1A10 UGT1A8 UGT1A7

3.24e-05181033EFO_0801382
DiseaseRh Deficiency Syndrome

RHCE RHD

3.61e-0531032C0272052
Diseaseindole-3-carboxylate measurement

UGT1A10 UGT1A8

3.61e-0531032EFO_0800043
DiseaseRh-Null, Regulator Type

RHCE RHD

3.61e-0531032C1849387
Diseaseblood 4-oxo-retinoic acid measurement

UGT1A10 UGT1A8

3.61e-0531032EFO_0022216
Diseasetissue factor measurement

UGT1A10 UGT1A8 UGT1A7

5.25e-05211033EFO_0010623
Diseasetemporal horn of lateral ventricle volume measurement

COL15A1 UGT1A10 ACO1 UGT1A8

1.20e-04721034EFO_0010333
Diseaseneuroblastoma, cutaneous melanoma

UGT1A10 UGT1A8 UGT1A7

1.27e-04281033EFO_0000389, EFO_0000621
Diseasexanthurenate measurement

UGT1A10 UGT1A8 UGT1A7

1.41e-04291033EFO_0010551
Diseaseresponse to dolutegravir

UGT1A10 UGT1A8 UGT1A7

1.57e-04301033EFO_0600017
Disease3-carboxy-4-methyl-5-pentyl-2-furanpropionate (3-CMPFP) measurement

UGT1A10 UGT1A8

1.79e-0461032EFO_0800566
Diseasethyroxine measurement

SGK1 UGT1A10 UGT1A8 UGT1A7

2.08e-04831034EFO_0005130
Diseasevitamin D deficiency

UGT1A10 UGT1A8 UGT1A7

2.94e-04371033EFO_0003762
Diseaserestless legs syndrome (implicated_via_orthology)

MEIS3 MEIS1

3.33e-0481032DOID:0050425 (implicated_via_orthology)
Diseasestatus epilepticus (biomarker_via_orthology)

POLG SLC8A2 SLC8A3 NLGN2

4.25e-041001034DOID:1824 (biomarker_via_orthology)
Diseaseepilepsy (is_implicated_in)

POLG BCHE

4.28e-0491032DOID:1826 (is_implicated_in)
Diseaseapolipoprotein B measurement

DDX19B UGT1A10 UGT1A8 UGT1A7 BCHE RHCE KCNK5 PLEC DOCK6

5.32e-046631039EFO_0004615
Diseaseindoleacetate measurement

UGT1A10 UGT1A8

5.33e-04101032EFO_0021015
Diseaseadseverin measurement

BCHE CPN1

5.33e-04101032EFO_0801358
Diseasevitamin D measurement, COVID-19

UGT1A10 UGT1A8 UGT1A7

6.77e-04491033EFO_0004631, MONDO_0100096
Diseaseautosomal dominant cerebellar ataxia (implicated_via_orthology)

ITPR2 ITPR3

7.78e-04121032DOID:1441 (implicated_via_orthology)
Diseasedodecanedioate measurement

UGT1A10 UGT1A8

7.78e-04121032EFO_0021054
DiseaseX-24588 measurement

UGT1A10 UGT1A8

9.18e-04131032EFO_0800898
Diseasebilirubin measurement

UGT1A10 UGT1A8 UGT1A7 MROH2A PIEZO1 RHCE PPP2R3A

9.30e-044421037EFO_0004570
Diseaseurate measurement, spine bone mineral density

UGT1A10 UGT1A8 UGT1A7

1.11e-03581033EFO_0004531, EFO_0007701
DiseaseMalignant neoplasm of breast

DYNC2H1 CYP17A1 BCHE COLGALT2 PKDREJ MEIS1 RHD SLC8A3 TAS2R13 STX5 AKT2

1.33e-03107410311C0006142
Diseasefood allergy measurement, parental genotype effect measurement

EML6 PROZ

1.78e-03181032EFO_0005939, EFO_0007016
Diseasetype 2 diabetes mellitus (biomarker_via_orthology)

UGT1A10 UGT1A8 UGT1A7 TRPC6

1.78e-031471034DOID:9352 (biomarker_via_orthology)
Diseaseplatelet crit

ATRX NUP210L PIEZO1 TRPC6 DOCK10 RHCE RHD ITPR2 PLEC MFSD13A

1.84e-0395210310EFO_0007985
Diseaseresponse to mitochondrial complex I inhibitor

GABBR2 GLCE

1.99e-03191032EFO_0600033
Diseaseleukemia (implicated_via_orthology)

MEIS3 MEIS1

1.99e-03191032DOID:1240 (implicated_via_orthology)
Diseasemalignant astrocytoma (is_marker_for)

ATRX AKT2

2.91e-03231032DOID:3069 (is_marker_for)
Diseasefunctional brain measurement

ACO1 TRPC6 SLC28A3

3.00e-03821033EFO_0007849
Diseaselongitudinal BMI measurement

CACNA1E SLC28A3 NUFIP1

3.00e-03821033EFO_0005937
Diseasehormone measurement

UGT1A10 UGT1A8 UGT1A7

3.21e-03841033EFO_0004730

Protein segments in the cluster

PeptideGeneStartEntry
FLKWGSQAFHNMRII

ACO1

156

P21399
KEVMEHRFFLSINWQ

AKT2

401

P31751
FHFINMWLFNRLVTD

AFDN

791

P55196
MHSKVTIICIRFLFW

BCHE

1

P06276
RWHFIMLNDTKRNTI

PRMT9

151

Q6P2P2
HMVKSQVFYWIVLSL

CACNA1E

471

Q15878
FTFSEFHLLKTMLLW

BTBD16

266

Q32M84
SFDHKWMVIQTLTRI

ARFGEF1

541

Q9Y6D6
SMQTHAARFKTFFNW

BIRC3

251

Q13489
HMAAFFAASDWLVRN

GLCE

401

O94923
RSTNLFMKLDSVFIW

ALDH3B2

6

P48448
LAHFWTTKAFLPAMT

HSD17B11

146

Q8NBQ5
KMQRTVNTIWFLHLT

C3AR1

51

Q16581
FWMTLQDFKTHFVLL

CAPN14

316

A8MX76
HETSARLLFMAVKWA

NR2E3

221

Q9Y5X4
MTWKVHSIRNNFTYL

OSMR

351

Q99650
HIWKLFENFLVDMAR

ITPR2

1446

Q14571
NTSWKINLFMQFRDH

ITPR3

216

Q14573
KVATNIMRAWLFQHL

MEIS1

281

O00470
KVLAILWFHSMDISF

OR52Z1P

66

P0C646
LDNTFLMTKLHFWRF

RSPH10B

436

P0C881
LDNTFLMTKLHFWRF

RSPH10B2

436

B2RC85
NAAFEIKLHWMAVTA

DEPDC5

1381

O75140
IKLHWMAVTAAVLFE

DEPDC5

1386

O75140
KWSNSFHHFVKMALT

MAP4K3

241

Q8IVH8
DLKWRHTLVIFTMSF

KCNJ8

66

Q15842
TWISRHKEMTFIFTD

LFNG

136

Q8NES3
IVSMEIFFKAWLHNS

M1AP

216

Q8TC57
AFVTSQRALIWKGHM

MMS22L

561

Q6ZRQ5
ALWRHFFSFLKSQRM

MMS22L

716

Q6ZRQ5
ITMFFHQTWKDSRLA

GABRQ

106

Q9UN88
LMASKIWTPDTFFHN

GABRA2

116

P47869
IVSTVQNFLFWHMKD

MFSD6L

381

Q8IWD5
VAEKMLTNWFTFLLH

PLXNA3

1411

P51805
FVNWKVSMFVEVHKA

KCNK5

241

O95279
HSRWTKALMEEFFRQ

PDE1B

381

Q01064
ALEINKMISFWRNAH

POLG

791

P54098
KMISFWRNAHKRISS

POLG

796

P54098
MELSWHVVFIALLSF

LCT

1

P09848
KVATNIMRAWLFQHL

MEIS3

271

Q99687
SQSSMIKHVAWLIFT

LGR4

741

Q9BXB1
LMASKIWTPDTFFHN

GABRA1

116

P14867
GFVTAQSFIAMWRKL

PPP2R3A

776

Q06190
TIVMFWKAFHKLTLE

HERC5

936

Q9UII4
NMKSRLEFTKEVFHW

DYNC2H1

2201

Q8NCM8
KLFQDFQMLSRIWTH

ATRX

1871

P46100
EKLTLFIANMWHDIF

ICE1

2026

Q9Y2F5
WHDIFLSQSVINKAM

ICE1

2036

Q9Y2F5
WMQVASLNEKRTFFH

KLHL13

421

Q9P2N7
EMRAHVNSSWFIFQK

KMO

366

O15229
HFWKVSTQGLFVAMF

BFAR

396

Q9NZS9
FVNRFQKWFQSMVHI

AWAT2

241

Q6E213
MKIQLFFFILHFWVT

DEFB110

1

Q30KQ9
IRWMHSFNFVLSANL

CPN1

201

P15169
FAAWMAQRLKTHLLT

DNASE2B

251

Q8WZ79
WFFFAIILKSMAQHL

DOCK10

991

Q96BY6
AILQHAWFFFQLMVK

DOCK6

926

Q96HP0
WFFFDVLIKSMAQHL

DOCK9

961

Q9BZ29
WQLHRRLAMATFALF

CYP17A1

121

P05093
AMIFCHTRKTASWLA

DDX19B

336

Q9UMR2
MFAKTWRVHAIFKNV

GABBR2

571

O75899
QFVSVGVKHMKFWTL

EML6

1521

Q6ZMW3
MFADRWLFSTNHKDI

MT-CO1

1

P00395
MIFCHTRKTASWLAA

DDX19A

336

Q9NUU7
SFMWSFEKIHRSLAH

FAM83H

246

Q6ZRV2
WPTSRFAHVMKLRQA

COLGALT2

136

Q8IYK4
AFSVPVMTHRWNRFA

COL15A1

151

P39059
KHGMTLRNWASFFVV

FAM87A

151

P0C7U9
ARHRNFLWFVSMDLV

MFSD13A

261

Q14CX5
KEHRRVFQAMWLSFL

NOC4L

246

Q9BVI4
MRRKTLLALFTDHQW

NLGN2

446

Q8NFZ4
FRLWMTTEAHKQFPI

DNAH5

4126

Q8TE73
IHTIILMVSSNFWFK

LRRC8D

171

Q7L1W4
HRRKFDNFSSLMLEW

NUP210L

806

Q5VU65
EFRQTWKLFSSHMNI

PPEF2

676

O14830
SVTWIAFFLQMRAKE

MROH2A

1101

A6NES4
GLRIMIFSWIVSNHF

TAS2R13

81

Q9NYV9
SRQVKHVMNFTNWAI

TRIM33

406

Q9UPN9
LKIAAMRKDFFSHAW

SLC9C1

661

Q4G0N8
MRKDFFSHAWNIFEL

SLC9C1

666

Q4G0N8
LRKNHMWFSIFASVV

PKDREJ

1366

Q9NTG1
FMEIKSHVFFSLINW

SGK1

346

O00141
MRVHNSTFLWFIPFV

SETX

401

Q7Z333
QTVMSKNLFWFRHRP

ST6GALNAC1

461

Q9NSC7
HMVLVTKVSRYSLWF

PROZ

381

P22891
VAAIFFVVWDHLMAK

SLC28A3

136

Q9HAS3
KFHSQLARALWTNML

PLB1

1006

Q6P1J6
VKNTFLRMWIYSHHI

RWDD2A

151

Q9UIY3
FQSVTSNRWLMVKIF

STX5

326

Q13190
LWVQFSHAMDALLFR

HTR3D

421

Q70Z44
ANVRFVAHWNIAKSM

RECQL5

326

O94762
AIGVWQMRHLKSFFE

TMED9

216

Q9BVK6
DSIIWAFKHTMRNVA

XPO1

876

O14980
MRTFKSSFSIWRHQV

ZBTB21

781

Q9ULJ3
SHWFTMQSVVEKLIL

UGT1A10

36

Q9HAW8
RHSWSSVAFNLFMLA

RHD

71

Q02161
RHSWSSVAFNLFMLA

RHCE

71

P18577
FTAHEKIVQFHWRNM

NUFIP1

206

Q9UHK0
NWLFLKSVPHFSMAA

TLR9

46

Q9NR96
NWFKRRASKFMTHVA

THG1L

116

Q9NWX6
MTFKQRWVRANHAAI

PSTK

301

Q8IV42
IFTTLVDTKWRHMFV

KCNJ16

61

Q9NPI9
VDTKWRHMFVIFSLS

KCNJ16

66

Q9NPI9
HSFVAAATKELMWLN

PLEC

756

Q15149
SKRFWMTAIVFTEIA

PIEZO1

1726

Q92508
FIARFMAFWHASKAQ

TRPC6

541

Q9Y210
SHWFTMQSVVEKLIL

UGT1A7

36

Q9HAW7
FVSVLHALMAALAQW

TTI1

756

O43156
SHWFTMQSVVEKLIL

UGT1A8

36

Q9HAW9
ESLARLVAMVFQWFH

UNC79

521

Q9P2D8
MHFLTVFWKVLFACV

SLC8A2

726

Q9UPR5
VMHFLTVFWKVLFAC

SLC8A3

731

P57103
FVFTPSQHWCKRTLM

NAPEPLD

246

Q6IQ20