Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	steroid binding	NPC1 CALB1 ANXA6 SIDT1 PTCH1 ERLIN1 SULT1E1 KL HSD11B1	2.50e-07	133	132	9	GO:0005496
GeneOntologyMolecularFunction	ribonucleoside triphosphate phosphatase activity	DDX19B ABCA4 DNAH2 RNF213 MCM2 GTPBP10 ABCB1 SEPTIN3 RAB24 SEPTIN1 ABCB11 DDX60L HSPA1L DIRAS2 DYNC1H1 RAC1 RAC2 RAC3	3.55e-06	775	132	18	GO:0017111
GeneOntologyMolecularFunction	pyrophosphatase activity	DDX19B ABCA4 DNAH2 RNF213 MCM2 GTPBP10 ABCB1 SEPTIN3 RAB24 SEPTIN1 ABCB11 DDX60L HSPA1L DIRAS2 DYNC1H1 RAC1 RAC2 RAC3	1.05e-05	839	132	18	GO:0016462
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides	DDX19B ABCA4 DNAH2 RNF213 MCM2 GTPBP10 ABCB1 SEPTIN3 RAB24 SEPTIN1 ABCB11 DDX60L HSPA1L DIRAS2 DYNC1H1 RAC1 RAC2 RAC3	1.07e-05	840	132	18	GO:0016817
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	DDX19B ABCA4 DNAH2 RNF213 MCM2 GTPBP10 ABCB1 SEPTIN3 RAB24 SEPTIN1 ABCB11 DDX60L HSPA1L DIRAS2 DYNC1H1 RAC1 RAC2 RAC3	1.07e-05	840	132	18	GO:0016818
GeneOntologyMolecularFunction	cholesterol binding	NPC1 ANXA6 SIDT1 PTCH1 ERLIN1	4.05e-05	58	132	5	GO:0015485
GeneOntologyMolecularFunction	GTP binding	ANXA6 SAMHD1 GTPBP10 SEPTIN3 RAB24 GUCY2C SEPTIN1 DIRAS2 RAC1 RAC2 RAC3	6.73e-05	397	132	11	GO:0005525
GeneOntologyMolecularFunction	lipid binding	NPC1 CPNE2 PLCZ1 ABCA4 CALB1 ACADVL MYO10 ANXA6 ATG2B SIDT1 PTCH1 ERLIN1 SULT1E1 CD1B KL PIK3C2G STARD9 HSD11B1	8.97e-05	988	132	18	GO:0008289
GeneOntologyMolecularFunction	sterol binding	NPC1 ANXA6 SIDT1 PTCH1 ERLIN1	1.07e-04	71	132	5	GO:0032934
GeneOntologyMolecularFunction	guanyl ribonucleotide binding	ANXA6 SAMHD1 GTPBP10 SEPTIN3 RAB24 GUCY2C SEPTIN1 DIRAS2 RAC1 RAC2 RAC3	1.63e-04	439	132	11	GO:0032561
GeneOntologyMolecularFunction	guanyl nucleotide binding	ANXA6 SAMHD1 GTPBP10 SEPTIN3 RAB24 GUCY2C SEPTIN1 DIRAS2 RAC1 RAC2 RAC3	1.63e-04	439	132	11	GO:0019001
GeneOntologyMolecularFunction	GTPase activity	ABCA4 GTPBP10 SEPTIN3 RAB24 SEPTIN1 DIRAS2 RAC1 RAC2 RAC3	4.48e-04	341	132	9	GO:0003924
GeneOntologyMolecularFunction	lyase activity	CA12 GAD1 FTCD GUCY2C PTS ASL HMGCLL1	5.29e-04	212	132	7	GO:0016829
GeneOntologyMolecularFunction	alcohol binding	NPC1 ANXA6 SIDT1 PTCH1 ERLIN1	5.84e-04	102	132	5	GO:0043178
GeneOntologyMolecularFunction	ATP hydrolysis activity	DDX19B ABCA4 DNAH2 RNF213 MCM2 ABCB1 ABCB11 DDX60L HSPA1L DYNC1H1	7.08e-04	441	132	10	GO:0016887
GeneOntologyMolecularFunction	vitamin binding	GAD1 ABCA4 CALB1 FOLR3 FTCD KL	7.10e-04	161	132	6	GO:0019842
GeneOntologyMolecularFunction	ATP-dependent activity	DDX19B ABCA4 MYO10 DNAH2 RNF213 MCM2 ABCB1 STARD9 ABCB11 DDX60L HSPA1L DYNC1H1	7.82e-04	614	132	12	GO:0140657
GeneOntologyMolecularFunction	phosphatidylethanolamine flippase activity	ABCA4 ABCB1	8.91e-04	7	132	2	GO:0090555
GeneOntologyMolecularFunction	calcium ion binding	PLCZ1 CALB1 PCDHGA3 ANXA6 CDH23 FAT1 TLL1 TLL2 EGFLAM PLCB4 EDEM1 PADI2 CDH3	1.40e-03	749	132	13	GO:0005509
GeneOntologyMolecularFunction	spectrin binding	MYO10 PTPRC USH1G	1.45e-03	34	132	3	GO:0030507
GeneOntologyMolecularFunction	vitamin D binding	CALB1 KL	1.51e-03	9	132	2	GO:0005499
GeneOntologyCellularComponent	apical part of cell	CA12 ANXA6 CDH23 CLDN4 PTCH1 ABCB1 FAT1 KL SHANK2 EGFR DSTYK ABCB11 ADAM17 HSD11B1 OSMR	3.86e-06	592	129	15	GO:0045177
GeneOntologyCellularComponent	cell cortex	GAD1 FLNB CALB1 MYO10 GRK4 SEPTIN3 RASAL3 SEPTIN1 DYNC1H1 PHLDB2 RAC1	1.95e-05	371	129	11	GO:0005938
GeneOntologyCellularComponent	apical plasma membrane	CA12 ANXA6 CLDN4 ABCB1 FAT1 KL SHANK2 EGFR DSTYK ABCB11 ADAM17 OSMR	4.96e-05	487	129	12	GO:0016324
GeneOntologyCellularComponent	cell-substrate junction	FLNB NRAP LAYN ANXA6 FAT1 PTPRC EGFR ADAM17 PHLDB2 RAC1 RAC2	9.66e-05	443	129	11	GO:0030055
GeneOntologyCellularComponent	anchoring junction	FLNB NRAP LAYN ANXA6 CLDN4 ABCB1 FAT1 PTPRC EGFR DSTYK ABCB11 ADAM17 CDH3 PHLDB2 RAC1 TBCD RAC2	1.07e-04	976	129	17	GO:0070161
GeneOntologyCellularComponent	NADPH oxidase complex	RAC1 RAC2 RAC3	1.75e-04	18	129	3	GO:0043020
GeneOntologyCellularComponent	focal adhesion	FLNB LAYN ANXA6 FAT1 PTPRC EGFR ADAM17 PHLDB2 RAC1 RAC2	3.47e-04	431	129	10	GO:0005925
GeneOntologyCellularComponent	cell leading edge	LAYN MYO10 FAT1 EGFR ROBO2 ADAM17 PHLDB2 RAC1 RAC2 RAC3	1.09e-03	500	129	10	GO:0031252
GeneOntologyCellularComponent	intercellular canaliculus	ABCB1 ABCB11	1.32e-03	9	129	2	GO:0046581
GeneOntologyCellularComponent	non-motile cilium	ABCA4 GRK4 CDH23 SHANK2 USH1G RAC1	1.38e-03	196	129	6	GO:0097730
GeneOntologyCellularComponent	somatodendritic compartment	GAD1 FLNB CALB1 MYO10 GRK4 DOCK10 SPG11 GRIK3 PTCH1 TMEM222 SERPINE2 SHANK2 ASL PLCB4 DYNC1H1 RAC1 RAC3	1.47e-03	1228	129	17	GO:0036477
GeneOntologyCellularComponent	glutamatergic synapse	CALB1 DOCK10 DGKE NBEA GRIK3 USP14 EFNB1 SHANK2 SRGAP3 ROBO2 PLCB4 RAC1 RAC3	1.64e-03	817	129	13	GO:0098978
MousePheno	abnormal cerebellum morphology	NPC1 POLR3GL SPG11 PTCH1 USP14 KL SERPINE2 SHANK2 EGFR STARD9 ROBO2 PLCB4 CPLANE1	8.33e-06	389	107	13	MP:0000849
MousePheno	abnormal cerebellar cortex morphology	NPC1 SPG11 PTCH1 USP14 KL SERPINE2 SHANK2 EGFR STARD9 ROBO2 PLCB4	1.84e-05	300	107	11	MP:0004097
MousePheno	abnormal metencephalon morphology	NPC1 POLR3GL SPG11 PTCH1 USP14 KL SERPINE2 SHANK2 EGFR STARD9 ROBO2 PLCB4 CPLANE1	1.88e-05	420	107	13	MP:0000847
MousePheno	abnormal cerebellar layer morphology	NPC1 SPG11 PTCH1 USP14 KL SERPINE2 SHANK2 EGFR STARD9 ROBO2	3.31e-05	263	107	10	MP:0009956
MousePheno	abnormal hindbrain morphology	NPC1 POLR3GL SPG11 PTCH1 USP14 KL SERPINE2 SHANK2 EGFR STARD9 ROBO2 PLCB4 CPLANE1	8.30e-05	485	107	13	MP:0000841
Domain	P-loop_NTPase	DDX19B ABCA4 MYO10 DNAH2 RNF213 MCM2 GTPBP10 ABCB1 SULT1E1 SEPTIN3 RAB24 STARD9 SEPTIN1 ABCB11 DDX60L DIRAS2 DYNC1H1 RAC1 RAC2 RAC3	1.86e-06	848	131	20	IPR027417
Domain	-	DDX19B ABCA4 DNAH2 RNF213 MCM2 GTPBP10 ABCB1 SULT1E1 SEPTIN3 RAB24 SEPTIN1 ABCB11 DDX60L DIRAS2 DYNC1H1 RAC1 RAC2 RAC3	4.70e-06	746	131	18	3.40.50.300
Domain	fn3	COL20A1 PTPRC ROBO2 EGFLAM OSMR TNXB EPHA1 MYBPC2	1.89e-05	162	131	8	PF00041
Domain	FN3	COL20A1 PTPRC ROBO2 EGFLAM OSMR TNXB EPHA1 MYBPC2	4.88e-05	185	131	8	SM00060
Domain	C2	CPNE2 PLCZ1 C2CD4C WWC2 RASAL3 PIK3C2G PLCB4	6.45e-05	142	131	7	PS50004
Domain	FN3	COL20A1 PTPRC ROBO2 EGFLAM OSMR TNXB EPHA1 MYBPC2	8.15e-05	199	131	8	PS50853
Domain	-	CPNE2 PLCZ1 C2CD4C WWC2 RASAL3 PIK3C2G PLCB4	8.37e-05	148	131	7	2.60.40.150
Domain	FN3_dom	COL20A1 PTPRC ROBO2 EGFLAM OSMR TNXB EPHA1 MYBPC2	1.15e-04	209	131	8	IPR003961
Domain	BMP_1/tolloid-like	TLL1 TLL2	1.46e-04	3	131	2	IPR015446
Domain	C2_dom	CPNE2 PLCZ1 C2CD4C WWC2 RASAL3 PIK3C2G PLCB4	1.59e-04	164	131	7	IPR000008
Domain	RHO	RAC1 RAC2 RAC3	3.52e-04	20	131	3	PS51420
Domain	AAA	ABCA4 DNAH2 RNF213 ABCB1 ABCB11 DYNC1H1	5.37e-04	144	131	6	SM00382
Domain	AAA+_ATPase	ABCA4 DNAH2 RNF213 ABCB1 ABCB11 DYNC1H1	5.37e-04	144	131	6	IPR003593
Domain	-	LGALS14 NBEA FAT1 CLC EGFLAM	5.50e-04	95	131	5	2.60.120.200
Domain	Peptidase_M12A	TLL1 TLL2	7.19e-04	6	131	2	IPR001506
Domain	Astacin	TLL1 TLL2	7.19e-04	6	131	2	PF01400
Domain	DHC_N1	DNAH2 DYNC1H1	1.33e-03	8	131	2	PF08385
Domain	Dynein_heavy_dom-1	DNAH2 DYNC1H1	1.33e-03	8	131	2	IPR013594
Domain	Ptc/Disp	NPC1 PTCH1	1.70e-03	9	131	2	IPR003392
Domain	Patched	NPC1 PTCH1	1.70e-03	9	131	2	PF02460
Domain	EGF	FAT1 TLL1 TLL2 EGFLAM TNXB	1.95e-03	126	131	5	PF00008
Domain	C2	CPNE2 PLCZ1 C2CD4C PIK3C2G PLCB4	2.31e-03	131	131	5	PF00168
Domain	EGF-like_CS	FAT1 TLL1 TLL2 EGFLAM ADAM17 TNXB EPHA1	2.47e-03	261	131	7	IPR013032
Domain	Ras	RAB24 DIRAS2 RAC1 RAC2 RAC3	2.72e-03	136	131	5	PF00071
Domain	C2	CPNE2 PLCZ1 C2CD4C PIK3C2G PLCB4	2.81e-03	137	131	5	SM00239
Domain	ABC_transporter_CS	ABCA4 ABCB1 ABCB11	3.17e-03	42	131	3	IPR017871
Domain	SAM	SAMHD1 SHANK2 USH1G EPHA1	3.42e-03	88	131	4	SM00454
Domain	G_SEPTIN_dom	SEPTIN3 SEPTIN1	3.62e-03	13	131	2	IPR030379
Domain	SSD	NPC1 PTCH1	3.62e-03	13	131	2	IPR000731
Domain	SSD	NPC1 PTCH1	3.62e-03	13	131	2	PS50156
Domain	Septin	SEPTIN3 SEPTIN1	3.62e-03	13	131	2	PF00735
Domain	G_SEPTIN	SEPTIN3 SEPTIN1	3.62e-03	13	131	2	PS51719
Domain	Ig-like_fold	FLNB COL20A1 VTCN1 CD1B PTPRC SHANK2 ROBO2 EGFLAM OSMR TNXB EPHA1 MYBPC2	4.07e-03	706	131	12	IPR013783
Domain	Dynein_heavy_chain_D4_dom	DNAH2 DYNC1H1	4.20e-03	14	131	2	IPR024317
Domain	Dynein_HC_stalk	DNAH2 DYNC1H1	4.20e-03	14	131	2	IPR024743
Domain	Dynein_heavy_dom-2	DNAH2 DYNC1H1	4.20e-03	14	131	2	IPR013602
Domain	DHC_N2	DNAH2 DYNC1H1	4.20e-03	14	131	2	PF08393
Domain	ATPase_dyneun-rel_AAA	DNAH2 DYNC1H1	4.20e-03	14	131	2	IPR011704
Domain	MT	DNAH2 DYNC1H1	4.20e-03	14	131	2	PF12777
Domain	AAA_8	DNAH2 DYNC1H1	4.20e-03	14	131	2	PF12780
Domain	Septin	SEPTIN3 SEPTIN1	4.20e-03	14	131	2	IPR016491
Domain	AAA_5	DNAH2 DYNC1H1	4.20e-03	14	131	2	PF07728
Domain	SAM_DOMAIN	SAMHD1 SHANK2 USH1G EPHA1	4.50e-03	95	131	4	PS50105
Domain	ConA-like_dom	COL20A1 LGALS14 NBEA FAT1 CLC EGFLAM	4.50e-03	219	131	6	IPR013320
Domain	ABC_tran	ABCA4 ABCB1 ABCB11	4.63e-03	48	131	3	PF00005
Domain	ABC_TRANSPORTER_2	ABCA4 ABCB1 ABCB11	4.63e-03	48	131	3	PS50893
Domain	DHC_fam	DNAH2 DYNC1H1	4.83e-03	15	131	2	IPR026983
Domain	EF-hand_like	PLCZ1 PLCB4	4.83e-03	15	131	2	PF09279
Domain	Galectin_CRD	LGALS14 CLC	4.83e-03	15	131	2	IPR001079
Domain	PI-PLC-Y	PLCZ1 PLCB4	4.83e-03	15	131	2	PF00387
Domain	PLCYc	PLCZ1 PLCB4	4.83e-03	15	131	2	SM00149
Domain	Dynein_heavy	DNAH2 DYNC1H1	4.83e-03	15	131	2	PF03028
Domain	PLipase_C_Pinositol-sp_Y	PLCZ1 PLCB4	4.83e-03	15	131	2	IPR001711
Domain	Gal-bind_lectin	LGALS14 CLC	4.83e-03	15	131	2	PF00337
Domain	PIPLC_Y_DOMAIN	PLCZ1 PLCB4	4.83e-03	15	131	2	PS50008
Domain	Gal-bind_lectin	LGALS14 CLC	4.83e-03	15	131	2	SM00908
Domain	Dynein_heavy_dom	DNAH2 DYNC1H1	4.83e-03	15	131	2	IPR004273
Domain	GALECTIN	LGALS14 CLC	4.83e-03	15	131	2	PS51304
Domain	PI-PLC_fam	PLCZ1 PLCB4	4.83e-03	15	131	2	IPR001192
Domain	PLC_EF-hand-like	PLCZ1 PLCB4	4.83e-03	15	131	2	IPR015359
Domain	GLECT	LGALS14 CLC	4.83e-03	15	131	2	SM00276
Domain	SAM	SAMHD1 SHANK2 USH1G EPHA1	4.84e-03	97	131	4	IPR001660
Domain	CUB	CSMD3 TLL1 TLL2	4.91e-03	49	131	3	PF00431
Domain	ABC_TRANSPORTER_1	ABCA4 ABCB1 ABCB11	4.91e-03	49	131	3	PS00211
Domain	ABC_transporter-like	ABCA4 ABCB1 ABCB11	5.20e-03	50	131	3	IPR003439
Domain	CUB	CSMD3 TLL1 TLL2	5.20e-03	50	131	3	SM00042
Domain	Small_GTPase	RAB24 DIRAS2 RAC1 RAC2 RAC3	5.43e-03	160	131	5	IPR001806
Domain	-	CSMD3 TLL1 TLL2	5.80e-03	52	131	3	2.60.120.290
Domain	CUB	CSMD3 TLL1 TLL2	6.12e-03	53	131	3	PS01180
Domain	Small_GTP-bd_dom	RAB24 DIRAS2 RAC1 RAC2 RAC3	6.49e-03	167	131	5	IPR005225
Domain	-	SAMHD1 SHANK2 USH1G EPHA1	6.62e-03	106	131	4	1.10.150.50
Domain	PI-PLC-X	PLCZ1 PLCB4	6.94e-03	18	131	2	PF00388
Domain	PLCXc	PLCZ1 PLCB4	6.94e-03	18	131	2	SM00148
Pathway	KEGG_MEDICUS_PATHOGEN_HCMV_GH_TO_ITGA_B_RHOA_SIGNALING_PATHWAY	RAC1 RAC2 RAC3	1.34e-05	7	104	3	M47538
Pathway	KEGG_MEDICUS_REFERENCE_IGG_FCGR_RAC_SIGNALING_PATHWAY	RAC1 RAC2 RAC3	4.51e-05	10	104	3	M47727
Pathway	KEGG_AXON_GUIDANCE	EFNB1 SRGAP3 ROBO2 RAC1 RAC2 EPHA1 RAC3	4.64e-05	129	104	7	M5539
Pathway	WP_RALA_DOWNSTREAM_REGULATED_GENES	RAC1 RAC2 RAC3	8.18e-05	12	104	3	M39408
Pubmed	Generation and characterization of Rac3 knockout mice.	GAD1 CALB1 RAC1 RAC2 RAC3	4.21e-11	8	133	5	15964829
Pubmed	Regulation of lymphatic-blood vessel separation by endothelial Rac1.	MKI67 RAC1 RAC2 RAC3	4.22e-08	10	133	4	19906871
Pubmed	rac, a novel ras-related family of proteins that are botulinum toxin substrates.	RAC1 RAC2 RAC3	5.47e-08	3	133	3	2674130
Pubmed	Isoform-specific membrane targeting mechanism of Rac during Fc gamma R-mediated phagocytosis: positive charge-dependent and independent targeting mechanism of Rac to the phagosome.	RAC1 RAC2 RAC3	5.47e-08	3	133	3	16081809
Pubmed	Signaling and cytoskeletal requirements in erythroblast enucleation.	RAC1 RAC2 RAC3	5.47e-08	3	133	3	22461493
Pubmed	Rac signaling in osteoblastic cells is required for normal bone development but is dispensable for hematopoietic development.	RAC1 RAC2 RAC3	5.47e-08	3	133	3	22123845
Pubmed	Pathophysiological Mechanisms in Neurodevelopmental Disorders Caused by Rac GTPases Dysregulation: What's behind Neuro-RACopathies.	RAC1 RAC2 RAC3	5.47e-08	3	133	3	34943902
Pubmed	Differential distribution of Rac1 and Rac3 GTPases in the developing mouse brain: implications for a role of Rac3 in Purkinje cell differentiation.	CALB1 SHANK2 RAC1 RAC3	1.42e-07	13	133	4	14622142
Pubmed	Rac1 controls the formation of midline commissures and the competency of tangential migration in ventral telencephalic neurons.	GAD1 CALB1 RAC1 RAC3	1.99e-07	14	133	4	17409253
Pubmed	Analysis of c-ErbB1/epidermal growth factor receptor and c-ErbB2/HER-2 expression in bronchial dysplasia: evaluation of potential targets for chemoprevention of lung cancer.	MCM2 EGFR MKI67	2.18e-07	4	133	3	16609045
Pubmed	Large-scale proteomics and phosphoproteomics of urinary exosomes.	NPC1 DDX19B FLNB CALB1 PSMA3 ANXA6 FTCD ABCB1 FAT1 KL EFNB1 CAPN7 ASL ABCB11 ROBO2 PADI2 DYNC1H1	3.70e-07	1016	133	17	19056867
Pubmed	PTEN negatively regulates engulfment of apoptotic cells by modulating activation of Rac GTPase.	RAC1 RAC2 RAC3	5.44e-07	5	133	3	22043008
Pubmed	Rac1 and rac3 GTPases control synergistically the development of cortical and hippocampal GABAergic interneurons.	GAD1 RAC1 RAC3	5.44e-07	5	133	3	23258346
Pubmed	Cadherin 8 regulates proliferation of cortical interneuron progenitors.	GAD1 CALB1 MKI67	1.08e-06	6	133	3	30315415
Pubmed	The role of Robo3 in the development of cortical interneurons.	GAD1 CALB1 ROBO2	1.08e-06	6	133	3	19366869
Pubmed	Immunohistochemical analysis of Disc1 expression in the developing and adult hippocampus.	GAD1 CALB1 MKI67	1.08e-06	6	133	3	18620078
Pubmed	Primary cilia regulate hippocampal neurogenesis by mediating sonic hedgehog signaling.	CALB1 MCM2 PTCH1 MKI67	1.71e-06	23	133	4	18728187
Pubmed	DDX3X Suppresses the Susceptibility of Hindbrain Lineages to Medulloblastoma.	CALB1 PTCH1 PTPRC MKI67	2.05e-06	24	133	4	32553121
Pubmed	A distinct Smoothened mutation causes severe cerebellar developmental defects and medulloblastoma in a novel transgenic mouse model.	CALB1 PTCH1 MKI67	3.02e-06	8	133	3	22869526
Pubmed	Essential function of histone deacetylase 1 in proliferation control and CDK inhibitor repression.	HDAC3 MKI67 TBXT	3.02e-06	8	133	3	12032080
Pubmed	Role of the Rho GTPase Rac in the activation of the phagocyte NADPH oxidase: outsourcing a key task.	RAC1 RAC2 RAC3	3.02e-06	8	133	3	24598074
Pubmed	CYBA encoding p22(phox), the cytochrome b558 alpha polypeptide: gene structure, expression, role and physiopathology.	RAC1 RAC2 RAC3	3.02e-06	8	133	3	27048830
Pubmed	The c-Ski family member and transcriptional regulator Corl2/Skor2 promotes early differentiation of cerebellar Purkinje cells.	GAD1 CALB1 PTCH1 MKI67	3.90e-06	28	133	4	24491816
Pubmed	Defective Wnt-dependent cerebellar midline fusion in a mouse model of Joubert syndrome.	CALB1 PTCH1 MKI67	4.52e-06	9	133	3	21623382
Pubmed	A Global Analysis of the Receptor Tyrosine Kinase-Protein Phosphatase Interactome.	PCDHGA3 PSMA3 DOCK10 WWC2 SHANK2 EGFR KIAA1217 HSD11B1 EDEM1 EPHA1	5.34e-06	420	133	10	28065597
Pubmed	Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia.	GAD1 FLNB FOLR3 FTCD PTCH1 ABCB1 EGFR ADAM17 PRDM16	5.56e-06	331	133	9	20634891
Pubmed	Rac1 deficiency in the forebrain results in neural progenitor reduction and microcephaly.	CALB1 MKI67 RAC1	6.43e-06	10	133	3	19007770
Pubmed	Visceral endoderm and the primitive streak interact to build the fetal-placental interface of the mouse gastrula.	PTCH1 MKI67 TBXT	6.43e-06	10	133	3	28882402
Pubmed	Dlx2 progenitor migration in wild type and Nkx2.1 mutant telencephalon.	GAD1 CALB1 MKI67	6.43e-06	10	133	3	12902388
Pubmed	The human formin FHOD1 contains a bipartite structure of FH3 and GTPase-binding domains required for activation.	RAC1 RAC2 RAC3	8.82e-06	11	133	3	18786395
Pubmed	Endothelial VEGF sculpts cortical cytoarchitecture.	GAD1 CALB1 MKI67	8.82e-06	11	133	3	24027281
Pubmed	FBXO11 constitutes a major negative regulator of MHC class II through ubiquitin-dependent proteasomal degradation of CIITA.	CUL1 FBXO11 HSPA1L	8.82e-06	11	133	3	37279268
Pubmed	Laminin-511 is an epithelial message promoting dermal papilla development and function during early hair morphogenesis.	PTCH1 SERPINE2 MKI67 CDH3	9.76e-06	35	133	4	18676816
Pubmed	The ciliary Frizzled-like receptor Tmem67 regulates canonical Wnt/β-catenin signalling in the developing cerebellum via Hoxb5.	CALB1 PTCH1 MKI67	1.17e-05	12	133	3	30931988
Pubmed	Developmental alterations of the septohippocampal cholinergic projection in a lissencephalic mouse model.	GAD1 CALB1 MKI67	1.17e-05	12	133	3	26079645
Pubmed	Reduced annexin A6 expression promotes the degradation of activated epidermal growth factor receptor and sensitizes invasive breast cancer cells to EGFR-targeted tyrosine kinase inhibitors.	ANXA6 EGFR	1.45e-05	2	133	2	24354805
Pubmed	ABCB11 and ABCB1 gene polymorphisms impact on telaprevir pharmacokinetic at one month of therapy.	ABCB1 ABCB11	1.45e-05	2	133	2	25661339
Pubmed	Transgenic rescue of ataxia mice with neuronal-specific expression of ubiquitin-specific protease 14.	CALB1 USP14	1.45e-05	2	133	2	17079671
Pubmed	Cetuximab directly inhibits P-glycoprotein function in vitro independently of EGFR binding.	ABCB1 EGFR	1.45e-05	2	133	2	25930120
Pubmed	Lack of Annexin A6 Exacerbates Liver Dysfunction and Reduces Lifespan of Niemann-Pick Type C Protein-Deficient Mice.	NPC1 ANXA6	1.45e-05	2	133	2	33345999
Pubmed	Hematopoietic cell regulation by Rac1 and Rac2 guanosine triphosphatases.	RAC1 RAC2	1.45e-05	2	133	2	14564009
Pubmed	Rac1 and Rac3 GTPases differently influence the morphological maturation of dendritic spines in hippocampal neurons.	RAC1 RAC3	1.45e-05	2	133	2	31369617
Pubmed	Rac regulates PtdInsP₃ signaling and the chemotactic compass through a redox-mediated feedback loop.	RAC1 RAC2	1.45e-05	2	133	2	21976675
Pubmed	Skin Barrier Defects Caused by Keratinocyte-Specific Deletion of ADAM17 or EGFR Are Based on Highly Similar Proteome and Degradome Alterations.	EGFR ADAM17	1.45e-05	2	133	2	27089454
Pubmed	Inhibition of Rac GTPase signaling and downstream prosurvival Bcl-2 proteins as combination targeted therapy in MLL-AF9 leukemia.	RAC1 RAC2	1.45e-05	2	133	2	21940819
Pubmed	Clinicopathological Value Of Epidermal Growth Factor Receptor (EGFR) And Ki-67 Expression In Colorectal Adenoma And Adenocarcinoma.	EGFR MKI67	1.45e-05	2	133	2	37482844
Pubmed	Chemoattractant-stimulated Rac activation in wild-type and Rac2-deficient murine neutrophils: preferential activation of Rac2 and Rac2 gene dosage effect on neutrophil functions.	RAC1 RAC2	1.45e-05	2	133	2	12391220
Pubmed	Deletion of Rac in Mature Osteoclasts Causes Osteopetrosis, an Age-Dependent Change in Osteoclast Number, and a Reduced Number of Osteoblasts In Vivo.	RAC1 RAC2	1.45e-05	2	133	2	26496249
Pubmed	Correlation of Ki-67 and MCM-2 proliferative marker expression with grade of histological malignancy (G) in ductal breast cancers.	MCM2 MKI67	1.45e-05	2	133	2	21097442
Pubmed	A disintegrin and metalloprotease 17 promotes microglial cell survival via epidermal growth factor receptor signalling following spinal cord injury.	EGFR ADAM17	1.45e-05	2	133	2	25738567
Pubmed	Selective Degradation Permits a Feedback Loop Controlling Annexin A6 and Cholesterol Levels in Endolysosomes of NPC1 Mutant Cells.	NPC1 ANXA6	1.45e-05	2	133	2	32392809
Pubmed	Rac1 and Rac3 GTPases regulate the development of hilar mossy cells by affecting the migration of their precursors to the hilus.	RAC1 RAC3	1.45e-05	2	133	2	21949760
Pubmed	SAMHD1-induced endosomal FAK signaling promotes human renal clear cell carcinoma metastasis by activating Rac1-mediated lamellipodia protrusion.	SAMHD1 RAC1	1.45e-05	2	133	2	37009792
Pubmed	Loss of Either Rac1 or Rac3 GTPase Differentially Affects the Behavior of Mutant Mice and the Development of Functional GABAergic Networks.	RAC1 RAC3	1.45e-05	2	133	2	26582364
Pubmed	Rac2 is required for the formation of neutrophil extracellular traps.	RAC1 RAC2	1.45e-05	2	133	2	21712395
Pubmed	A disintegrin and metalloproteinase 17 (ADAM17) and epidermal growth factor receptor (EGFR) signaling drive the epithelial response to Staphylococcus aureus toxic shock syndrome toxin-1 (TSST-1).	EGFR ADAM17	1.45e-05	2	133	2	22833676
Pubmed	Serpine2/PN-1 Is Required for Proliferative Expansion of Pre-Neoplastic Lesions and Malignant Progression to Medulloblastoma.	PTCH1 SERPINE2	1.45e-05	2	133	2	25901736
Pubmed	Rac-Dependent Signaling from Keratinocytes Promotes Differentiation of Intradermal White Adipocytes.	RAC1 RAC3	1.45e-05	2	133	2	31351086
Pubmed	Rac1/2 activation promotes FGFR1 driven leukemogenesis in stem cell leukemia/lymphoma syndrome.	RAC1 RAC2	1.45e-05	2	133	2	31221776
Pubmed	Specific roles of Rac1 and Rac2 in motile functions of HT1080 fibrosarcoma cells.	RAC1 RAC2	1.45e-05	2	133	2	19555660
Pubmed	Extracellular oxidation in cystic fibrosis airway epithelium causes enhanced EGFR/ADAM17 activity.	EGFR ADAM17	1.45e-05	2	133	2	29351448
Pubmed	Rac GTPases differentially integrate signals regulating hematopoietic stem cell localization.	RAC1 RAC2	1.45e-05	2	133	2	16025125
Pubmed	Roles of the Rac1 and Rac3 GTPases in human tumor cell invasion.	RAC1 RAC3	1.45e-05	2	133	2	16027728
Pubmed	Structure and chromosomal assignment to 22q12 and 17qter of the ras-related Rac2 and Rac3 human genes.	RAC2 RAC3	1.45e-05	2	133	2	9299243
Pubmed	Transforming mutations of RAC guanosine triphosphatases in human cancers.	RAC1 RAC2	1.45e-05	2	133	2	23382236
Pubmed	Rac1 and Rac3 isoform activation is involved in the invasive and metastatic phenotype of human breast cancer cells.	RAC1 RAC3	1.45e-05	2	133	2	16280046
Pubmed	RAC1B function is essential for breast cancer stem cell maintenance and chemoresistance of breast tumor cells.	RAC1 RAC3	1.45e-05	2	133	2	36599922
Pubmed	Absence of Rac1 and Rac3 GTPases in the nervous system hinders thymic, splenic and immune-competence development.	RAC1 RAC3	1.45e-05	2	133	2	21469092
Pubmed	Shedding of klotho by ADAMs in the kidney.	KL ADAM17	1.45e-05	2	133	2	26155844
Pubmed	Rac1 and Rac3 have opposing functions in cell adhesion and differentiation of neuronal cells.	RAC1 RAC3	1.45e-05	2	133	2	17244648
Pubmed	Lapatinib-induced annexin A6 upregulation as an adaptive response of triple-negative breast cancer cells to EGFR tyrosine kinase inhibitors.	ANXA6 EGFR	1.45e-05	2	133	2	30590459
Pubmed	Rac1 and Rac2 regulate macrophage morphology but are not essential for migration.	RAC1 RAC2	1.45e-05	2	133	2	16772332
Pubmed	Heterozygous mutation of Ush1g/Sans in mice causes early-onset progressive hearing loss, which is recovered by reconstituting the strain-specific mutation in Cdh23.	CDH23 USH1G	1.45e-05	2	133	2	26936824
Pubmed	Rac deletion in osteoclasts causes severe osteopetrosis.	RAC1 RAC2	1.45e-05	2	133	2	22114304
Pubmed	Rac GTPases regulate the morphology and deformability of the erythrocyte cytoskeleton.	RAC1 RAC2	1.45e-05	2	133	2	16882712
Pubmed	The cellular function of srGAP3 and its role in neuronal morphogenesis.	SRGAP3 RAC1	1.45e-05	2	133	2	23127797
Pubmed	Decreased ADAM17 expression in the lungs of α-Klotho reduced mouse.	KL ADAM17	1.45e-05	2	133	2	31951006
Pubmed	ADAM17 transactivates EGFR signaling during embryonic eyelid closure.	EGFR ADAM17	1.45e-05	2	133	2	23211830
Pubmed	The role of Rac1 and Rac2 in bacterial killing.	RAC1 RAC2	1.45e-05	2	133	2	16157315
Pubmed	mdr1a deficiency corrects sterility in Niemann-Pick C1 protein deficient female mice.	NPC1 ABCB1	1.45e-05	2	133	2	11984826
Pubmed	Distinct ADAM metalloproteinases regulate G protein-coupled receptor-induced cell proliferation and survival.	EGFR ADAM17	1.45e-05	2	133	2	15337756
Pubmed	Rac-deficient cerebellar granule neurons die before they migrate to the internal granule layer.	RAC1 RAC3	1.45e-05	2	133	2	36050459
Pubmed	Rac1 and Rac3 have opposite functions in Schwann cells during developmental myelination.	RAC1 RAC3	1.45e-05	2	133	2	33812927
Pubmed	A disintegrin and metalloproteinase 17 (ADAM17) mediates epidermal growth factor receptor transactivation by angiotensin II on hepatic stellate cells.	EGFR ADAM17	1.45e-05	2	133	2	24412389
Pubmed	SrGAP3 interacts with lamellipodin at the cell membrane and regulates Rac-dependent cellular protrusions.	SRGAP3 RAC1	1.45e-05	2	133	2	22159416
Pubmed	Identification of a Protein Network Driving Neuritogenesis of MGE-Derived GABAergic Interneurons.	RAC1 RAC3	1.45e-05	2	133	2	28066185
Pubmed	Rac GTPase isoform-specific regulation of NADPH oxidase and chemotaxis in murine neutrophils in vivo. Role of the C-terminal polybasic domain.	RAC1 RAC2	1.45e-05	2	133	2	15504745
Pubmed	Rac2-deficient murine macrophages have selective defects in superoxide production and phagocytosis of opsonized particles.	RAC1 RAC2	1.45e-05	2	133	2	15528331
Pubmed	Dispensable role of Rac1 and Rac3 after cochlear hair cell specification.	RAC1 RAC3	1.45e-05	2	133	2	37204479
Pubmed	Pivotal Advance: Phospholipids determine net membrane surface charge resulting in differential localization of active Rac1 and Rac2.	RAC1 RAC2	1.45e-05	2	133	2	19955208
Pubmed	Inhibition of Rac activity alleviates lipopolysaccharide-induced acute pulmonary injury in mice.	RAC1 RAC2	1.45e-05	2	133	2	21511011
Pubmed	Interaction between p21-activated protein kinase and Rac during differentiation of HL-60 human promyelocytic leukemia cell induced by all-trans-retinoic acid.	RAC1 RAC2	1.45e-05	2	133	2	12027902
Pubmed	Migration of growth factor-stimulated epithelial and endothelial cells depends on EGFR transactivation by ADAM17.	EGFR ADAM17	1.45e-05	2	133	2	21407195
Pubmed	The metalloproteinase ADAM17 and the epidermal growth factor receptor (EGFR) signaling drive the inflammatory epithelial response in Sjögren's syndrome.	EGFR ADAM17	1.45e-05	2	133	2	24664458
Pubmed	Cutting edge: Rac GTPases sensitize activated T cells to die via Fas.	RAC1 RAC2	1.45e-05	2	133	2	17982024
Pubmed	Rac guanosine triphosphatases represent integrating molecular therapeutic targets for BCR-ABL-induced myeloproliferative disease.	RAC1 RAC2	1.45e-05	2	133	2	17996650
Pubmed	Osimertinib (AZD9291), a Mutant-Selective EGFR Inhibitor, Reverses ABCB1-Mediated Drug Resistance in Cancer Cells.	ABCB1 EGFR	1.45e-05	2	133	2	27649127
Pubmed	Oligodendrocyte Regeneration and CNS Remyelination Require TACE/ADAM17.	EGFR ADAM17	1.45e-05	2	133	2	26338334
Pubmed	TACE/ADAM17 is essential for oligodendrocyte development and CNS myelination.	EGFR ADAM17	1.45e-05	2	133	2	25186737
Pubmed	Yin-and-yang bifurcation of opioidergic circuits for descending analgesia at the midbrain of the mouse.	GAD1 PLCB4	1.45e-05	2	133	2	30297409
Interaction	ADGRL1 interactions	LDLRAD1 PSMA3 CD1B SHANK2 RAC1 RAC2 RAC3	1.35e-06	85	131	7	int:ADGRL1
Interaction	SWAP70 interactions	CUL1 EGFR DYNC1H1 RAC1 RAC2 RAC3	1.18e-05	78	131	6	int:SWAP70
Interaction	ABI1 interactions	PSMA3 CDH23 SPG11 EGFR KIAA1217 MKI67 RAC1 RAC2 RAC3	1.56e-05	223	131	9	int:ABI1
Interaction	LSR interactions	LDLRAD1 VPS45 CLDN4 CD1B EGFR RAC1 RAC2 RAC3	2.09e-05	177	131	8	int:LSR
Interaction	OCLN interactions	MON2 LDLRAD1 NBEA CLDN4 C2CD4C CD1B EFNB1 EGFR ROBO2 PHLDB2 RAC1 RAC2 RAC3	2.34e-05	500	131	13	int:OCLN
Interaction	HLA-B interactions	MON2 RNF213 PTCH1 CD1B EGFR EDEM1 RAC1 RAC2 RAC3	2.69e-05	239	131	9	int:HLA-B
Interaction	PLAC9 interactions	RNF213 FBXO11 EFNB1 RAC3	3.57e-05	29	131	4	int:PLAC9
Interaction	RAP1GDS1 interactions	USP14 EGFR HSPA1L DIRAS2 RAC1 RAC2 RAC3	3.83e-05	141	131	7	int:RAP1GDS1
Interaction	HDAC7 interactions	BCORL1 KRBA2 HDAC3 EGFR RAC1 RAC2 RAC3	3.83e-05	141	131	7	int:HDAC7
Interaction	CXCR4 interactions	DDX19B SPG11 USP14 EFNB1 PTPRC DSTYK RAC1 RAC2 RAC3	4.46e-05	255	131	9	int:CXCR4
Interaction	CYFIP2 interactions	PSMA3 SPG11 EGFR SRGAP3 KIAA1217 RAC1 TBCD RAC2 EPHA1 RAC3	5.07e-05	323	131	10	int:CYFIP2
Interaction	PLCB4 interactions	PLCB4 RAC1 RAC2 RAC3	5.32e-05	32	131	4	int:PLCB4
Interaction	CPNE8 interactions	RNF213 MCM2 EGFR RAC1 RAC2 RAC3	6.39e-05	105	131	6	int:CPNE8
Interaction	AKAP12 interactions	SAMHD1 CLDN4 EGFR DYNC1H1 RAC1 RAC2 RAC3	7.28e-05	156	131	7	int:AKAP12
Interaction	ATP11A interactions	NPC1 RAC1 RAC2 RAC3	7.64e-05	35	131	4	int:ATP11A
Interaction	ZDHHC20 interactions	NPC1 RAC1 RAC2 RAC3	8.55e-05	36	131	4	int:ZDHHC20
Interaction	CEMIP2 interactions	CLDN4 PTCH1 EGFR RAC1 RAC2 RAC3	1.06e-04	115	131	6	int:CEMIP2
Cytoband	3q13.2	SIDT1 CFAP44 PHLDB2	1.01e-04	31	133	3	3q13.2
Cytoband	17q25.3	RNF213 NARF TBCD RAC3	2.21e-04	101	133	4	17q25.3
Cytoband	12p12	PIK3C2G GUCY2C	6.36e-04	13	133	2	12p12
GeneFamily	Fibronectin type III domain containing	COL20A1 PTPRC ROBO2 EGFLAM OSMR TNXB EPHA1 MYBPC2	1.84e-06	160	94	8	555
GeneFamily	Rho family GTPases	RAC1 RAC2 RAC3	1.46e-04	20	94	3	390
GeneFamily	Bone morphogenetic proteins\|Astacins	TLL1 TLL2	3.96e-04	6	94	2	894
GeneFamily	Sterile alpha motif domain containing	SAMHD1 SHANK2 USH1G EPHA1	1.14e-03	88	94	4	760
GeneFamily	ATP binding cassette subfamily B	ABCB1 ABCB11	1.43e-03	11	94	2	806
GeneFamily	Septins	SEPTIN3 SEPTIN1	2.01e-03	13	94	2	732
GeneFamily	Galectins	LGALS14 CLC	2.69e-03	15	94	2	629
GeneFamily	Cadherin related	CDH23 FAT1	3.46e-03	17	94	2	24
GeneFamily	Phospholipases\|C2 domain containing phospholipases	PLCZ1 PLCB4	4.32e-03	19	94	2	832
Coexpression	GSE339_CD4POS_VS_CD8POS_DC_UP	NPC1 SAMHD1 ABCB1 FBXO8 RAB24 RASAL3 PTS RAC2	8.20e-06	200	132	8	M5108
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HDA1	CALB1 FBXO11 NBEA GRIK3 CSMD3 C2CD4C SEPTIN3 SHANK2 ROBO2 PLCB4 CDH3 HMGCLL1	4.12e-05	584	132	12	M39068
Coexpression	ODONNELL_METASTASIS_UP	BCORL1 FAT1 SHANK2 TLL2 PLCB4	4.16e-05	76	132	5	M265
Coexpression	HUANG_DASATINIB_SENSITIVITY_UP	LAYN MYO10 EGFR OSMR RAC2	5.33e-05	80	132	5	M3015
Coexpression	KYNG_DNA_DAMAGE_BY_4NQO_OR_GAMMA_RADIATION	SERPINE2 EGFR EPHA1	5.43e-05	15	132	3	M19053
Coexpression	GSE411_WT_VS_SOCS3_KO_MACROPHAGE_IL6_STIM_400MIN_UP	FLNB PSMA3 ERLIN1 SRGAP3 MKI67 NCOA7 EDEM1	7.15e-05	200	132	7	M5994
Coexpression	GSE1460_CD4_THYMOCYTE_VS_NAIVE_CD4_TCELL_CORD_BLOOD_UP	NPC1 CUL1 FBXO11 PTCH1 ABCB1 CD1B RAC2	7.15e-05	200	132	7	M3470
Coexpression	GSE32533_MIR17_KO_VS_MIR17_OVEREXPRESS_ACT_CD4_TCELL_UP	CA12 COL20A1 PTPRC RASAL3 EDEM1 NUP160 RBM41	7.15e-05	200	132	7	M8468
Coexpression	GSE21546_SAP1A_KO_VS_SAP1A_KO_AND_ELK1_KO_ANTI_CD3_STIM_DP_THYMOCYTES_DN	CA12 PTPRC HSD11B1 EDEM1 PADI2 DIRAS2 RAC2	7.15e-05	200	132	7	M7526
Coexpression	HALLMARK_APICAL_JUNCTION	NRAP LAYN CLDN4 PTPRC EGFR CDH3 RAC2	7.15e-05	200	132	7	M5915
Coexpression	GSE36078_WT_VS_IL1R_KO_LUNG_DC_AFTER_AD5_T425A_HEXON_INF_UP	ANXA6 SAMHD1 RSPH6A HDAC3 MKI67 ACAA2 PADI2	7.15e-05	200	132	7	M9294
Coexpression	MURARO_PANCREAS_DUCTAL_CELL	CA12 ACADVL MYO10 VTCN1 RNF213 CLDN4 ABCB1 FAT1 PTPRC EGFR KIAA1217 NCOA7 ACAA2 OSMR PRDM16 PHLDB2 RAC1 RAC2	7.42e-05	1276	132	18	M39173
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HRGL2B	CA12 CPNE2 PTCH1 CSMD3 FAT1 SERPINE2 EGFR SRGAP3 MKI67 CFAP44	7.95e-05	439	132	10	M39054
Coexpression	MEISSNER_BRAIN_HCP_WITH_H3K4ME3_AND_H3K27ME3	CPNE2 GAD1 MYO10 SIDT1 GRIK3 C2CD4C SERPINE2 EGFR KIAA1217 TLL1 TLL2 EGFLAM OSMR PRDM16 DIRAS2 PHLDB2	1.03e-04	1074	132	16	M1941
Coexpression	CHARAFE_BREAST_CANCER_LUMINAL_VS_MESENCHYMAL_UP	CA12 EXPH5 VPS45 MKNK2 SIDT1 CLDN4 SHANK2 PADI2 CDH3 EPHA1	1.07e-04	455	132	10	M17299
Coexpression	FLECHNER_BIOPSY_KIDNEY_TRANSPLANT_REJECTED_VS_OK_DN	CA12 DDX19B CALB1 EXPH5 MINPP1 ABCB1 USP14 FAT1 KL SHANK2 ACAA2	1.16e-04	553	132	11	M1475
Coexpression	JONES_OVARY_GRANULOSA	MYO10 PSMA3 ANXA6 SERPINE2 CDH3	1.27e-04	96	132	5	M48347
ToppCell	Children_(3_yrs)-Epithelial-club_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	FLNB VTCN1 NBEA FAT1 SHANK2 SRGAP3 KIAA1217 TLL1	7.82e-08	182	133	8	215c303df42f13597b2c7a95cb157c6bc7aca9a1
ToppCell	IPF-Epithelial-Basal\|IPF / Disease state, Lineage and Cell class	CLDN4 FAT1 EGFR SRGAP3 KIAA1217 OSMR CDH3 PHLDB2	1.09e-07	190	133	8	ea19e9ce954f2dfde97388db9695325cd92ab88f
ToppCell	Control-Epithelial-Club\|Control / Disease state, Lineage and Cell class	EXPH5 CLDN4 FAT1 SHANK2 EGFR KIAA1217 OSMR PRDM16	1.18e-07	192	133	8	d84ed1ea4a03edaa18c804f75afb03bd7b1f0e16
ToppCell	control-Lymphoid-Treg\|Lymphoid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	ERICH1 LAYN RNF213 ABCB1 PTPRC RASAL3 SEPTIN1 NCOA7	1.33e-07	195	133	8	66959ae839eb60a573da06bdd227090ebb5bb9ed
ToppCell	distal-Hematologic-Natural_Killer_T-3\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ANXA6 ABCB1 PTPRC RASAL3 SEPTIN1 TBCD RAC2 EPHA1	1.38e-07	196	133	8	05d2a15ba702b07ef59c55891a06da02cdd15f7f
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.2.4\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CLDN4 FAT1 EGFR KIAA1217 NCOA7 OSMR CDH3 PHLDB2	1.49e-07	198	133	8	77517df37dc894c78ef1e2b24dd7ba31f928bdb7
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CA12 VTCN1 CLDN4 FAT1 EGFR KIAA1217 NCOA7 CDH3	1.55e-07	199	133	8	c88a28a73f54dc571f2ff1e4b55073f83cbead2c
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Rspo1_Itga4\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	CPNE2 GAD1 PLCZ1 DOCK10 CLDN4 CSMD3 HSD11B1	2.64e-07	144	133	7	7de962346ba9653d90dd13bb7d977fe44d200bba
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CA12 CALB1 KL PIK3C2G PLCB4 PRDM16 HMGCLL1	4.95e-07	158	133	7	7960337d87afecf2692ab65e5991f052ceddfacc
ToppCell	3'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.1.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CA12 LAYN VTCN1 ZNF507 EGFR PIK3C2G SRGAP3	5.16e-07	159	133	7	22427ad4ad2e797e4664e7a7b0514094f22a18b2
ToppCell	Children_(3_yrs)-Epithelial-lung_goblet_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	VTCN1 NBEA GRIK3 SHANK2 SRGAP3 KIAA1217 TLL1	5.62e-07	161	133	7	2d63b279d9a5132e1c09b03930bf9039036d24a2
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Pygm_C1ql1\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	GAD1 PLCZ1 DOCK10 NBEA CSMD3 SERPINE2 EGFR	5.62e-07	161	133	7	3b5d7a3dab479c6959a428f3954dedd989900276
ToppCell	droplet-Lung-nan-3m-Lymphocytic-NK_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANXA6 RASAL3 SEPTIN1 HSD11B1 PADI2 RAC2 RAC3	5.86e-07	162	133	7	4b490989005bb03d4e7bbea01580f8548eff150f
ToppCell	droplet-Lung-nan-18m-Lymphocytic-Natural_Killer\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRC RASAL3 SEPTIN1 HSD11B1 PADI2 RAC2 RAC3	5.86e-07	162	133	7	66069146e2666d13c594bd76247893354a697c5d
ToppCell	droplet-Lung-nan-3m-Lymphocytic-Natural_Killer\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANXA6 RASAL3 SEPTIN1 HSD11B1 PADI2 RAC2 RAC3	5.86e-07	162	133	7	e4a09bf1a51710f6c57e6e01edf8b4619459d96d
ToppCell	droplet-Lung-nan-18m-Lymphocytic-NK_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRC RASAL3 SEPTIN1 HSD11B1 PADI2 RAC2 RAC3	6.11e-07	163	133	7	801163c05f8fdacaebd0cb9b4c92741276bfa3e3
ToppCell	droplet-Lung-18m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PTPRC RASAL3 SEPTIN1 HSD11B1 PADI2 RAC2 RAC3	6.36e-07	164	133	7	d4d08353c7322f97ea07dd583b08661d635fff20
ToppCell	droplet-Lung-18m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell-natural_killer\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PTPRC RASAL3 SEPTIN1 HSD11B1 PADI2 RAC2 RAC3	6.36e-07	164	133	7	c2cd4e4b88cc1b80a9494f59d31339007ff824c1
ToppCell	droplet-Lung-18m-Hematologic-Lymphocytic_NK_ILC\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PTPRC RASAL3 SEPTIN1 HSD11B1 PADI2 RAC2 RAC3	6.63e-07	165	133	7	88745bf7ecb0f7fc93077cea20171d40535dd56b
ToppCell	PND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD8_T-CD8_T_prolif\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SIDT1 DOCK10 ABCB1 PTPRC RASAL3 SEPTIN1 RAC2	6.63e-07	165	133	7	5f606959a060b1ae241217889560c6761ac73bbb
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2-Exc_L6_FEZF2_ETV4\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PLCZ1 EXPH5 GRIK3 SERPINE2 PIK3C2G KIAA1217 ROBO2	7.79e-07	169	133	7	716e9d4c5fb99c56b76afaa5ed90bfa859fde802
ToppCell	droplet-Lung-30m-Hematologic-myeloid-myeloid_dendritic_cell-dendritic_type_2\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CPNE2 LDLRAD1 DOCK10 SEPTIN3 GUCY2C SRGAP3 NCOA7	9.11e-07	173	133	7	70c0c13febd28b395fb3171ec8d7fbbc6c9d4eb7
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GRIK3 ABCB1 KL KIAA1217 ROBO2 PLCB4 DIRAS2	1.06e-06	177	133	7	4c069f0d044a96118090b85ca592a21d6b5d9399
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CA12 CALB1 EXPH5 KL PIK3C2G PLCB4 PRDM16	1.14e-06	179	133	7	666072c0e8448dbaec1683d18368ec2502453f90
ToppCell	facs-Kidney-nan-24m-Lymphocytic-T_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANXA6 SIDT1 PTPRC RASAL3 SEPTIN1 PADI2 RAC2	1.28e-06	182	133	7	e5f62ce9b9e0d28627617f7cbc81026f8442e402
ToppCell	facs-Kidney-nan-24m-Lymphocytic-T_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANXA6 SIDT1 PTPRC RASAL3 SEPTIN1 PADI2 RAC2	1.28e-06	182	133	7	0e16824c721d8b7d527157cb65feec909f6b974c
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CA12 GAD1 CALB1 EXPH5 PIK3C2G PLCB4 PRDM16	1.28e-06	182	133	7	5f513bbb7125956eb528e3120de3fd776770a7c3
ToppCell	Control-Epithelial-Basal\|World / Disease state, Lineage and Cell class	CLDN4 FAT1 EGFR SRGAP3 KIAA1217 OSMR CDH3	1.28e-06	182	133	7	759390dde9b18757f7675d13d44c89d0e32f8d93
ToppCell	Children_(3_yrs)-Epithelial-lung_goblet_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	FLNB VTCN1 NBEA SHANK2 SRGAP3 KIAA1217 TLL1	1.28e-06	182	133	7	3f1a666fe27dd7529c114539ed5f6b8ca585c875
ToppCell	Epithelial-lung_goblet_cell\|World / Lineage, Cell type, age group and donor	VTCN1 NBEA SHANK2 SRGAP3 KIAA1217 TLL1 DIRAS2	1.33e-06	183	133	7	940cbe298e9c53b5622af09264586ed823d3141f
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CA12 GAD1 CALB1 EXPH5 KL PIK3C2G HMGCLL1	1.33e-06	183	133	7	2f0ee40e69ad1259e56e8ee4b352736900eb8901
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CA12 CALB1 EXPH5 KL PIK3C2G PLCB4 PRDM16	1.33e-06	183	133	7	2e831a4d99c6f983793df71c0994124c943c6da9
ToppCell	facs-SCAT-Fat-18m-Lymphocytic-CD8-positive,_alpha-beta_T_cell\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANXA6 SIDT1 PTPRC RASAL3 SEPTIN1 PADI2 RAC2	1.38e-06	184	133	7	f9365feed31e48f3382588bab077f99c5a3f5b04
ToppCell	facs-Liver-Non-hepatocytes-3m-Lymphocytic-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CA12 DOCK10 PTPRC RASAL3 SEPTIN1 PADI2 RAC2	1.38e-06	184	133	7	8fc047977fad38fcd26eebcc279a688efd342ed8
ToppCell	COVID-19-kidney-CD-IC-B\|kidney / Disease (COVID-19 only), tissue and cell type	CA12 MYO10 SAMHD1 CSMD3 EGFR NCOA7 PRDM16	1.53e-06	187	133	7	ce05b89860573fe0356102e2998d1ef6d1968034
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CA12 GAD1 CALB1 EXPH5 KL PIK3C2G PRDM16	1.59e-06	188	133	7	eec3d353e51358db4c7621265ee0fdd4298e5b0e
ToppCell	COVID-19-lung-Secretory\|lung / Disease (COVID-19 only), tissue and cell type	FLNB VTCN1 NBEA SHANK2 SRGAP3 KIAA1217 CDH3	1.64e-06	189	133	7	84d48e3ed25bebb8bb8074b3a2c5e2e88cff7f25
ToppCell	PCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	EXPH5 CLDN4 SHANK2 TLL1 PLCB4 PRDM16 CDH3	1.64e-06	189	133	7	7659c7bbd58ee959a159294fb8d17317bbcc5681
ToppCell	PCW_05-06-Epithelial-Epithelial_proliferating-epi_proliferating2_(13)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	EXPH5 CLDN4 SHANK2 PIK3C2G MKI67 PLCB4 PRDM16	1.64e-06	189	133	7	c8b8f860aaf6c73863cd79941db6b469c830ef06
ToppCell	PCW_07-8.5-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	EXPH5 CLDN4 SHANK2 PIK3C2G PLCB4 PRDM16 CDH3	1.70e-06	190	133	7	625c08a0e5227efc46daa512fd579c3938ff76c7
ToppCell	metastatic_Lymph_Node-T/NK_cells-Exhausted_CD8+_T\|metastatic_Lymph_Node / Location, Cell class and cell subclass	LAYN PTPRC RASAL3 SRGAP3 SEPTIN1 TBCD RAC2	1.70e-06	190	133	7	cb4cf8ae2156c20b7978ae2e55aa605b4e90f455
ToppCell	Adult-Epithelial-club_cell\|Adult / Lineage, Cell type, age group and donor	VTCN1 NBEA FAT1 SHANK2 SRGAP3 KIAA1217 TLL1	1.70e-06	190	133	7	756bff697d30aec56c0ebfca94295f084a15bf37
ToppCell	Children_(3_yrs)-Epithelial-club_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	VTCN1 NBEA FAT1 SHANK2 KIAA1217 TLL1 PRDM16	1.76e-06	191	133	7	23776c7302cead3881b39127398f3b3e0d27885e
ToppCell	control-Lymphoid-Treg\|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	ANXA6 DOCK10 ABCB1 PTPRC RASAL3 SEPTIN1 RAC2	1.83e-06	192	133	7	9067e90b7c2d734100d6e5026d753113bf9428a3
ToppCell	NS-moderate-d_16-33-Lymphoid-Treg\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	ANXA6 DOCK10 ABCB1 PTPRC RASAL3 SEPTIN1 RAC2	1.83e-06	192	133	7	48d557071bad80edd3ec6e5ad8dcd97037da9553
ToppCell	NS-control-d_0-4-Lymphoid-Treg\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	ANXA6 DOCK10 ABCB1 PTPRC RASAL3 SEPTIN1 RAC2	1.83e-06	192	133	7	ef252dd9df161f665f53c047c0514381f80d6683
ToppCell	Epithelial-club_cell\|World / Lineage, Cell type, age group and donor	VTCN1 NBEA FAT1 SHANK2 KIAA1217 TLL1 PRDM16	1.89e-06	193	133	7	2bdd09004fa433550958ec42ba4b06271a4aaf7c
ToppCell	NS-moderate-d_0-4\|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	EXPH5 DNAH2 EGFR SRGAP3 CPLANE1 CFAP44 MAP3K19	1.89e-06	193	133	7	ea345d34440b25f65358a53dc72831998d1c3620
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L4-6_SST_MTHFD2P6\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GAD1 LGALS14 GRIK3 KIAA1217 TLL2 ROBO2 CDH3	1.89e-06	193	133	7	2c15186d15545804cc262da9137ab825609d4b2c
ToppCell	PCW_07-8.5-Epithelial\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	EXPH5 CLDN4 SHANK2 TLL1 PLCB4 PRDM16 CDH3	1.96e-06	194	133	7	f63ceedb88a9abc8644ee94adfd541e7817c1e3a
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CA12 VTCN1 NBEA CLDN4 FAT1 PIK3C2G PRDM16	2.02e-06	195	133	7	3d6d3de8ada6dce3dc789c15b50cc066e7100496
ToppCell	tumor_Lymph_Node_/_Brain-T/NK_cells-Exhausted_CD8+_T\|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass	ANXA6 PTPRC RASAL3 SRGAP3 SEPTIN1 TBCD RAC2	2.02e-06	195	133	7	f2029195d5b655120a9e84074b2583e2d89c0a1d
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CA12 CALB1 EXPH5 FOLR3 KL PIK3C2G CDH3	2.09e-06	196	133	7	f40d10ea7714067585493fdc89744714aa427de8
ToppCell	mild-low-quality_cells\|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	NPC1 ZNF507 RNF213 DGKE PTCH1 STARD9 PHLDB2	2.17e-06	197	133	7	e4331969bd911d1ebb5453f40a7057297b5389b4
ToppCell	3'-Broncho-tracheal\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	LAYN CLDN4 SULT1E1 EGFR SRGAP3 NCOA7 CDH3	2.17e-06	197	133	7	5d33f8a6940431093e927b186fb9b630a89d8ec1
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.1.3\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CA12 VTCN1 CLDN4 EGFR KIAA1217 NCOA7 CDH3	2.17e-06	197	133	7	233b9fcb376e08d0080a05ca0198ecc6ec720f90
ToppCell	Severe_COVID-19-T/NK-NK\|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）	SIDT1 ABCB1 NARF SERPINE2 RASAL3 SRGAP3 RAC2	2.17e-06	197	133	7	cc20162892b59e48653981f91fc9a0c27064444d
ToppCell	systemic_lupus_erythematosus-treated\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	ANXA6 RNF213 SAMHD1 PTPRC RAB24 DDX60L RAC2	2.24e-06	198	133	7	8165ff735095c52994fb5057d89be93cc378b7da
ToppCell	distal-3-Hematologic-Natural_Killer_T\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ANXA6 ABCB1 PTPRC RASAL3 SEPTIN1 TBCD RAC2	2.24e-06	198	133	7	b5da18f2a3554dca36e88be3b96a89089c2f2e1d
ToppCell	COVID-19_Mild\|World / Disease condition and Cell class	CUL1 RNF213 SAMHD1 MED13L PTPRC DDX60L DYNC1H1	2.24e-06	198	133	7	61ceb2245b6cb58e308b999a61d218c89dbc615e
ToppCell	3'-Broncho-tracheal-Epithelial\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	LAYN CLDN4 SULT1E1 EGFR SRGAP3 NCOA7 CDH3	2.24e-06	198	133	7	aa6e7218ee6230902854e66c444b544218b30c0e
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_submucosal-gland\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FLNB VTCN1 NBEA SHANK2 SRGAP3 KIAA1217 TLL1	2.24e-06	198	133	7	fab3135f03cf23a9f04f0eed543a9dc181f39f5f
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Igfbp6_Car10\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	CPNE2 GAD1 DOCK10 CSMD3 FAT1 TLL1	2.30e-06	127	133	6	f808c727c0817ed10e76eaffa9493a516e9a6b50
ToppCell	BAL-Mild-Lymphocyte-T/NK-CD8+_T-CD8+_T\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ANXA6 ABCB1 PTPRC RASAL3 SEPTIN1 RAC2 EPHA1	2.32e-06	199	133	7	8c4ebdedfb808cf2fc6629295b4d3fab8e562053
ToppCell	BAL-Mild-Lymphocyte-T/NK-CD8+_T-CD8+_T-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ANXA6 ABCB1 PTPRC RASAL3 SEPTIN1 RAC2 EPHA1	2.32e-06	199	133	7	7345b424b27951cd55f7f06f9503a7d44a881cd1
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Duct\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FLNB VTCN1 NBEA PIK3C2G SRGAP3 KIAA1217 TLL1	2.39e-06	200	133	7	b992eeddee38e6fe3564e9b1850f6b20b89bf47d
ToppCell	Macroglial-Polydendrocytes\|Macroglial / cells hierarchy compared to all cells using T-Statistic	GAD1 COL20A1 GRIK3 CSMD3 KIAA1217 TLL1 PLCB4	2.39e-06	200	133	7	961858738ce35db8760c8c2e136f8369bc444ccf
ToppCell	Macroglial-Polydendrocytes-PDGFRA-\|Macroglial / cells hierarchy compared to all cells using T-Statistic	GAD1 COL20A1 GRIK3 CSMD3 KIAA1217 TLL1 PLCB4	2.39e-06	200	133	7	f17b5a54e8f9eba9dcd0808ba4e8d275ac41bce2
ToppCell	Macroglial-Polydendrocytes-PDGFRA--\|Macroglial / cells hierarchy compared to all cells using T-Statistic	GAD1 COL20A1 GRIK3 CSMD3 KIAA1217 TLL1 PLCB4	2.39e-06	200	133	7	cc3409518f8b436ea92deb955e81114b3f410ff7
ToppCell	Macroglial-Polydendrocytes-PDGFRA\|Macroglial / cells hierarchy compared to all cells using T-Statistic	GAD1 COL20A1 GRIK3 CSMD3 KIAA1217 TLL1 PLCB4	2.39e-06	200	133	7	c24a3099e3d96d8b72f6d05286bb355d661a0377
ToppCell	Macroglial-Polydendrocytes-PDGFRA---\|Macroglial / cells hierarchy compared to all cells using T-Statistic	GAD1 COL20A1 GRIK3 CSMD3 KIAA1217 TLL1 PLCB4	2.39e-06	200	133	7	4fc3de4bff7ed2bf40b38462c4b4e9b87af6a4ca
ToppCell	Macroglial-Polydendrocytes-PDGFRA----L1-6\|Macroglial / cells hierarchy compared to all cells using T-Statistic	GAD1 COL20A1 GRIK3 CSMD3 KIAA1217 TLL1 PLCB4	2.39e-06	200	133	7	310cd53db1c137f6af74e6ae682221d7ac27310c
ToppCell	PND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SIDT1 PTPRC RASAL3 SEPTIN1 PADI2 RAC2	5.56e-06	148	133	6	7cb4865a1e9522e24f9c14799568b67172bd99dc
ToppCell	facs-GAT-Fat-3m-Lymphocytic-NK_cell\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CALB1 PTPRC RASAL3 SEPTIN1 PADI2 RAC2	6.24e-06	151	133	6	3d07b79ecbcfad13116f0f2b039bd181a7ffe853
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Rspo1_Itga4\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	CPNE2 GAD1 PLCZ1 DOCK10 CSMD3 SERPINE2	7.25e-06	155	133	6	cba6f3f7742b4d5d54ad0a0ac0dd4016e73fe658
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Rspo4_Rxfp1_Chat\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	CPNE2 GAD1 PLCZ1 DOCK10 CSMD3 EGFR	7.25e-06	155	133	6	3b8def9e8f66511736ea37f259511f7c8b7743af
ToppCell	PND03-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD4_T-CD4_T_prolif\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SIDT1 MCM2 PTPRC RASAL3 SEPTIN1 RAC2	8.39e-06	159	133	6	a5509f0604ef0caef5ed1af83dd89c86686c73cc
ToppCell	droplet-Kidney-nan-24m-Lymphocytic-NK_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANXA6 PTPRC RASAL3 SEPTIN1 PADI2 RAC2	9.67e-06	163	133	6	d18fee517e0daed51f89703f94f218567c83cb03
ToppCell	droplet-Kidney-nan-24m-Lymphocytic-CD45____NK_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANXA6 PTPRC RASAL3 SEPTIN1 PADI2 RAC2	9.67e-06	163	133	6	f4a6e28ad3c1fcbf62ed9b2bf09f65d2ab0b31d1
ToppCell	facs-BAT-Fat-3m-Lymphocytic-NK_cell\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANXA6 SIDT1 PTPRC SEPTIN1 HSD11B1 PADI2	1.00e-05	164	133	6	cbdb7e893cb3959b9920c0c7c535ace03a5f4986
ToppCell	droplet-Lung-immune-endo-depleted-3m-Lymphocytic-NK_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRC SEPTIN1 HSD11B1 PADI2 RAC2 RAC3	1.04e-05	165	133	6	93ed399b8c6278e5f1528c07758fb502d80a1a8b
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Crispld2_Htr2c\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	CPNE2 GAD1 PLCZ1 DOCK10 CSMD3 SERPINE2	1.04e-05	165	133	6	c6b23013d77fa9aa967b76e451c8e42b0a657c30
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Lymphocytic_T/NK-T_Cell-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SIDT1 DOCK10 SAMHD1 PTPRC RASAL3 RAC2	1.04e-05	165	133	6	5fc5e34cc805df44c020256729256ef761790152
ToppCell	droplet-Lung-immune-endo-depleted-3m-Lymphocytic-Natural_Killer\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRC SEPTIN1 HSD11B1 PADI2 RAC2 RAC3	1.04e-05	165	133	6	80f82aaab48791cb06fcb2d8ed7821f162742385
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Lymphocytic_T/NK-T_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SIDT1 DOCK10 SAMHD1 PTPRC RASAL3 RAC2	1.04e-05	165	133	6	8dbd03795fff060cd2e4d5d97348f5b63515e030
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Lymphocytic_T/NK\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SIDT1 DOCK10 SAMHD1 PTPRC RASAL3 RAC2	1.04e-05	165	133	6	64c7c45383afde1d050934938705e47aa615755f
ToppCell	droplet-Lung-immune-endo-depleted-3m-Lymphocytic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRC SEPTIN1 HSD11B1 PADI2 RAC2 RAC3	1.07e-05	166	133	6	3213466380becf0ee3d4d9a0776ccbb1ee4eccea
ToppCell	droplet-Lung-nan-21m-Lymphocytic-Natural_Killer\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRC SEPTIN1 HSD11B1 PADI2 RAC2 RAC3	1.07e-05	166	133	6	be45610f2fe606c328f5688189be40df5e678557
ToppCell	droplet-Lung-LUNG-30m-Lymphocytic-NK_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANXA6 RASAL3 SEPTIN1 HSD11B1 PADI2 RAC2	1.07e-05	166	133	6	0b7503e27e26dcbf7f1b893c32ce0b21ce58bd4a
ToppCell	droplet-Lung-nan-21m-Lymphocytic-NK_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRC SEPTIN1 HSD11B1 PADI2 RAC2 RAC3	1.07e-05	166	133	6	325ece9d7dad2b92eeb4defa109853660ac133ca
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c04-COTL1\|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)	CALB1 SIDT1 CSMD3 RASAL3 UNC45B HSPA1L	1.11e-05	167	133	6	3b717d33aaf1ef0869cc4bca8432ba8008875cc5
ToppCell	367C-Myeloid-Macrophage-FABP4+_Macrophage_3\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	LAYN ZNF507 SERPINE2 PLCB4 HMGCLL1 PHLDB2	1.11e-05	167	133	6	5c82d801e3b7d7c6c967a73b94b2ee2a8da1fd6e
ToppCell	Adult-Epithelial-lung_goblet_cell-D122\|Adult / Lineage, Cell type, age group and donor	VTCN1 GRIK3 SRGAP3 KIAA1217 TLL1 PLCB4	1.11e-05	167	133	6	6efbb2ef6adc8da5dd67210969f825f5cc8ed022
ToppCell	Immune_cells-NK_cells\|Immune_cells / Lineage and Cell class	ANXA6 SIDT1 EFNB1 PTPRC SEPTIN1 HSD11B1	1.15e-05	168	133	6	125d70c37eb49eb4d1f503bb8d536b225254c7cb
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GRIK3 ABCB1 KL KIAA1217 ROBO2 DIRAS2	1.15e-05	168	133	6	7abaddbcc55e44653d54aa15464266aa6bd5c9d2
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CLDN4 RSPH6A WWC2 SHANK2 KIAA1217 PRDM16	1.23e-05	170	133	6	a2c738e441ced90eeeb1fcc6ca3269b918aaa298
ToppCell	Control-Epithelial_cells-ECM-high_epithelial\|Control / group, cell type (main and fine annotations)	FLNB WWC2 SHANK2 EGFR NCOA7 PHLDB2	1.23e-05	170	133	6	e2023d66e70983c87dacbd6181d3426488d1fc57
ToppCell	PND03-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PTPRC RASAL3 MKI67 SEPTIN1 PADI2 RAC2	1.23e-05	170	133	6	da4dde7d0491ccc298cec7474a6a76ff3db36a4c
ToppCell	droplet-Lung-21m-Hematologic-Lymphocytic_NK_ILC\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PTPRC SEPTIN1 HSD11B1 PADI2 RAC2 RAC3	1.27e-05	171	133	6	dfaa6eb9c1835fdcaececc975b303ea8c2e9629d
ToppCell	droplet-Lung-21m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell-natural_killer\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PTPRC SEPTIN1 HSD11B1 PADI2 RAC2 RAC3	1.27e-05	171	133	6	91f18271e280e64c7a790ca29e453c10510f525a
Drug	2-Acetylaminofluorene	CLDN4 ABCB1 SULT1E1 PTPRC EGFR MKI67 ACAA2 OSMR POLK PADI2 CDH3 RAC1 EPHA1	7.83e-07	409	132	13	ctd:D015073
Drug	B258	RAC1 RAC2 RAC3	3.76e-06	6	132	3	CID000593690
Drug	AC1L9K72	NPC1 PLCZ1 ABCA4 COL20A1 ANXA6 DGKE ABCB1 CLC PLCB4 RAC2	7.65e-06	290	132	10	CID000446872
Disease	autosomal dominant intellectual developmental disorder 48 (implicated_via_orthology)	RAC1 RAC2 RAC3	8.75e-08	3	132	3	DOID:0080235 (implicated_via_orthology)
Disease	Vesico-Ureteral Reflux	DSTYK ROBO2 TNXB	3.49e-07	4	132	3	C0042580
Disease	Malignant neoplasm of breast	FLNB ABCA4 BCORL1 DGKE GRIK3 CLDN4 ABCB1 SERPINE2 PTPRC FBXO8 EGFR UNC45B SRGAP3 ASL TLL1 MKI67 HSD11B1 RAC2	1.50e-06	1074	132	18	C0006142
Disease	cystic fibrosis (implicated_via_orthology)	ABCB1 ABCB11 EDEM1	7.21e-06	9	132	3	DOID:1485 (implicated_via_orthology)
Disease	Neonatal inflammatory skin and bowel disease	EGFR ADAM17	1.99e-05	2	132	2	C4751120
Disease	kidney disease (implicated_via_orthology)	KL RAC1 RAC2 RAC3	3.41e-05	41	132	4	DOID:557 (implicated_via_orthology)
Disease	Colorectal Neoplasms	ABCA4 ABCB1 FAT1 EGFR GUCY2C MKI67 ABCB11 EPHA1	3.68e-05	277	132	8	C0009404
Disease	lung non-small cell carcinoma (is_implicated_in)	CA12 FBXO11 ABCB1 HDAC3 FAT1 EGFR	3.95e-05	139	132	6	DOID:3908 (is_implicated_in)
Disease	stomach cancer (is_marker_for)	FBXO11 NBEA PTCH1 EFNB1 MKI67 RAC1	4.45e-05	142	132	6	DOID:10534 (is_marker_for)
Disease	Familial vesicoureteral reflux	ROBO2 TNXB	5.94e-05	3	132	2	cv:C4706552
Disease	Familial vesicoureteral reflux	ROBO2 TNXB	5.94e-05	3	132	2	C4706552
Disease	Vesicoureteral reflux	ROBO2 TNXB	5.94e-05	3	132	2	cv:C0042580
Disease	hepatocellular carcinoma (is_marker_for)	CA12 ANXA6 BCORL1 FBXO11 PTCH1 EGFR ASL RAC1	6.59e-05	301	132	8	DOID:684 (is_marker_for)
Disease	Colorectal Carcinoma	ERICH1 ABCA4 GRIK3 CSMD3 ABCB1 FAT1 KL EGFR GUCY2C MKI67 ABCB11 EPHA1	7.76e-05	702	132	12	C0009402
Disease	serum alanine aminotransferase measurement	NPC1 LDLRAD1 EXPH5 BCORL1 DNAH2 GRIK3 PTCH1 TMEM222 ERLIN1 ABCB1 DSTYK ABCB11 NUP160	1.47e-04	869	132	13	EFO_0004735
Disease	Intellectual Disability	NBEA MED13L SHANK2 SRGAP3 PTS DYNC1H1 RAC1 TBCD RAC3	1.90e-04	447	132	9	C3714756
Disease	Usher syndrome, type 1A	CDH23 USH1G	1.97e-04	5	132	2	C2931205
Disease	vesicoureteral reflux (is_implicated_in)	ROBO2 TNXB	1.97e-04	5	132	2	DOID:9620 (is_implicated_in)
Disease	USHER SYNDROME, TYPE IB (disorder)	CDH23 USH1G	1.97e-04	5	132	2	C1848638
Disease	USHER SYNDROME, TYPE IA, FORMERLY	CDH23 USH1G	1.97e-04	5	132	2	C1848639
Disease	USHER SYNDROME, TYPE I, FRENCH VARIETY, FORMERLY	CDH23 USH1G	1.97e-04	5	132	2	C1848640
Disease	Usher syndrome type 1	CDH23 USH1G	1.97e-04	5	132	2	cv:C1568247
Disease	mean platelet volume	PCDHGA3 GRK4 BCORL1 SIDT1 DOCK10 CLDN4 RSPH6A NARF SERPINE2 PTPRC DSTYK PRDM16 TBCD RAC2	1.98e-04	1020	132	14	EFO_0004584
Disease	aspartate aminotransferase measurement	FLNB ABCA4 DNAH2 RNF213 PTCH1 ERLIN1 ABCB1 WWC2 SEPTIN3 PTPRC DSTYK ABCB11 NUP160	2.16e-04	904	132	13	EFO_0004736
Disease	alcohol use disorder (implicated_via_orthology)	GAD1 GRK4 EGFR RAC1 RAC2 RAC3	2.53e-04	195	132	6	DOID:1574 (implicated_via_orthology)
Disease	Usher Syndrome, Type I	CDH23 USH1G	2.94e-04	6	132	2	C1568247
Disease	esophagus squamous cell carcinoma (is_marker_for)	CA12 PTCH1 FAT1 EGFR	3.45e-04	74	132	4	DOID:3748 (is_marker_for)
Disease	Hereditary retinal dystrophy	CDH23 USH1G	4.11e-04	7	132	2	C0154860
Disease	Usher syndrome	CDH23 USH1G	4.11e-04	7	132	2	cv:C0271097
Disease	Profound Mental Retardation	MED13L SHANK2 SRGAP3 DYNC1H1 TBCD	4.13e-04	139	132	5	C0020796
Disease	Mental Retardation, Psychosocial	MED13L SHANK2 SRGAP3 DYNC1H1 TBCD	4.13e-04	139	132	5	C0025363
Disease	Mental deficiency	MED13L SHANK2 SRGAP3 DYNC1H1 TBCD	4.13e-04	139	132	5	C0917816
Disease	Disorder of fatty acid metabolism	SLC25A20 ACADVL	7.00e-04	9	132	2	cv:C0268634
Disease	Cleft upper lip	ABCA4 FBXO11 PTCH1	7.11e-04	39	132	3	C0008924
Disease	Liver Cirrhosis, Experimental	DOCK10 NBEA FTCD ABCB1 SULT1E1 FAT1 PTPRC MKI67 ROBO2 ADAM17 RAC2	7.37e-04	774	132	11	C0023893
Disease	epilepsy (implicated_via_orthology)	GAD1 ABCB1 DYNC1H1 RAC1 RAC2	8.51e-04	163	132	5	DOID:1826 (implicated_via_orthology)
Disease	lymphocyte count	FLNB EXPH5 PCDHGA3 ANXA6 DOCK10 CDH23 SAMHD1 MED13L SEPTIN3 PTPRC RASAL3 EGFR ROBO2 DDX60L NUP160 RAC2	8.59e-04	1464	132	16	EFO_0004587
Disease	response to carboplatin, response to antineoplastic agent	FLNB AKNAD1	8.73e-04	10	132	2	GO_0097327, GO_0097328
Disease	high grade glioma (implicated_via_orthology)	ABCB1 EGFR MKI67	1.01e-03	44	132	3	DOID:3070 (implicated_via_orthology)
Disease	Heart Diseases	HDAC3 UNC45B RAC2	1.15e-03	46	132	3	C0018799
Disease	peptic esophagitis (biomarker_via_orthology)	CLDN4 EGFR	1.27e-03	12	132	2	DOID:13976 (biomarker_via_orthology)
Disease	gallbladder carcinoma (is_marker_for)	PTCH1 RAC1	1.27e-03	12	132	2	DOID:4948 (is_marker_for)
Disease	Malformations of Cortical Development	DYNC1H1 TBCD	1.74e-03	14	132	2	C1955869
Disease	bipolar disorder, response to lithium ion	EGFR PTS	1.74e-03	14	132	2	GO_0010226, MONDO_0004985
Disease	Cortical Dysplasia	DYNC1H1 TBCD	1.74e-03	14	132	2	C0431380
Disease	colorectal cancer (is_implicated_in)	FAT1 EGFR MKI67 RAC1	2.17e-03	121	132	4	DOID:9256 (is_implicated_in)
Disease	Moyamoya Disease	RNF213 SAMHD1	2.58e-03	17	132	2	C0026654
Disease	platelet-derived growth factor BB measurement	DOCK10 SERPINE2 DSTYK	2.61e-03	61	132	3	EFO_0008264
Disease	Disorder of eye	ABCA4 CDH23 USH1G CPLANE1 CDH3	2.70e-03	212	132	5	C0015397
Disease	cutaneous melanoma, hair color	MED13L DSTYK CDH3	2.73e-03	62	132	3	EFO_0000389, EFO_0003924
Disease	essential hypertension (is_implicated_in)	GRK4 HSD11B1	2.90e-03	18	132	2	DOID:10825 (is_implicated_in)
Disease	Adrenocortical carcinoma	ABCB1 EGFR	2.90e-03	18	132	2	C0206686
Disease	inflammatory bowel disease (is_implicated_in)	EGFR ADAM17	3.23e-03	19	132	2	DOID:0050589 (is_implicated_in)
Disease	neutrophil count	NPC1 FLNB POLR3GL VPS45 BCORL1 CDH23 CD1B DHRS12 PTPRC DSTYK ASL PLCB4 TNXB NUP160	3.63e-03	1382	132	14	EFO_0004833
Disease	Manic Disorder	GAD1 SHANK2 STARD9	4.01e-03	71	132	3	C0024713
Disease	ulcerative colitis	PTPRC FAM3A OSMR PRDM16 CDH3 TNXB	4.06e-03	335	132	6	EFO_0000729
Disease	neurodegenerative disease (implicated_via_orthology)	PSMA3 GRIK3 PTCH1 DYNC1H1	4.16e-03	145	132	4	DOID:1289 (implicated_via_orthology)
Disease	Liver diseases	NPC1 SULT1E1 RAC1	4.17e-03	72	132	3	C0023895
Disease	Liver Dysfunction	NPC1 SULT1E1 RAC1	4.17e-03	72	132	3	C0086565

Protein segments in the cluster

Peptide	Gene	Start	Entry
SDVMFVRQGTYANPK	USH1G	251	Q495M9
AKAAGVSFMYQPEDS	ERICH1	181	Q86X53
SFGDKPYGEMSNQEV	EPHA1	821	P21709
MVIKGLDPDTNYQFA	EGFLAM	201	Q63HQ2
GQIIQDYDSDKMFPA	CPNE2	346	Q96FN4
AFENPMYDTNAKSVE	CSMD3	3676	Q7Z407
FLYKGPRESQADDMA	ABCA4	481	P78363
KGDEVIAVASMNYDP	AIFM3	551	Q96NN9
KIYFGSNIPNMFVDS	ERLIN1	296	O75477
QPKMDYAGNVAEAEG	BCORL1	96	Q5H9F3
AAKEANAYNFIMDLP	ABCB11	531	O95342
YSANEEFRPEMLQGK	HSD11B1	21	P28845
DFAGDFQMKYPFEIQ	CD1B	101	P29016
VPKAQTSYGFAMLAE	C2CD4C	141	Q8TF44
KSTYQAEVMENSPAG	CDH23	1961	Q9H251
EAQVYMGDFNLKTAP	CFAP44	1166	Q96MT7
IQAAAETAYDMVSPG	ATG2B	1951	Q96BY7
DPNQDAEALYTAMKG	ANXA6	21	P08133
QVAMVDVDAAPSGYQ	RASAL3	681	Q86YV0
PYQNTIGAAFVAKVM	RAB24	36	Q969Q5
NKGDPMNNLESFYQE	RBM41	181	Q96IZ5
NYVSQLASPMFGDKD	OSMR	916	Q99650
VFDNYSANVMVDSKP	RAC2	36	P15153
VFDNYSANVMVDGKP	RAC3	36	P60763
VFDNYSANVMVDGKP	RAC1	36	P63000
FEDNVTAPDYMKNVL	GUCY2C	281	P25092
SEMEYFITEGGKNPQ	PIK3C2G	1076	O75747
QSAGPFEVNMEETIY	MCM2	356	P49736
MAVGQVSSFAPDYAK	ABCB1	986	P08183
NAPVFMQAEYTGLIS	FAT1	1761	Q14517
AFSPVMNYKDGISSE	MED13L	876	Q71F56
DYEQQRGKGSFPAMI	NRAP	231	Q86VF7
NDIYEFSPDQMGRSK	LAYN	356	Q6UX15
AVDPIMEKFNASIAY	ASL	16	P04424
MPKAGYSSILNDFVE	DDX60L	21	Q5H9U9
AVLIEMGSFNPSYDK	CA12	171	O43570
TTMVGYQPQGDKANF	GAD1	551	Q99259
YQPQGDKANFFRMVI	GAD1	556	Q99259
EAYVPVSDMNGLGFK	FLNB	1731	O75369
NMLFESIQEGKYEFP	MKNK2	316	Q9HBH9
FNANPDEGVNYFMSK	FBXO8	146	Q9NRD0
SPIMEAFGNAKTVYN	MYO10	201	Q9HD67
VESKNMPFQDGQEFE	CLC	76	Q05315
YKGFNAVMIRAFPAN	SLC25A20	266	O43772
PFQIKNNVEDAMGNY	EXPH5	1051	Q8NEV8
GENKAFYPEEISSMV	HSPA1L	111	P34931
TFVAADGKSYQVPML	SERPINE2	206	P07093
PNEEVAKFYAAAMNA	FOLR3	221	P41439
MNKVFPQGENGYTAA	LDLRAD1	1	Q5T700
SGEKNIYAFMGTPVQ	MKI67	1546	P46013
DMAYGNNKEPSLFAV	MON2	781	Q7Z3U7
MYINPSAKEGDTFNK	OR2AP1	256	Q8NGE2
MSDSDKVGVFYVENP	PADI2	206	Q9Y2J8
NMEYGRNFSGPDKDV	FOXRED2	496	Q8IWF2
MAPELFTGKYDNSVD	DSTYK	816	Q6XUX3
MAKTVAYFYDPDVGN	HDAC3	1	O15379
YFAVTNNNIEMLPDG	LRRC8B	706	Q6P9F7
EYMFNKDNGQAPFTI	NPC1	191	O15118
EGFNAQVSYILDKMP	PCDHGA3	271	Q9Y5H0
VFVASYDDPATKMNE	FAM3A	146	P98173
FPESLKVYGAVMNIN	GLYATL3	21	Q5SZD4
QMDVNPEGKYSFGAT	EGFR	276	P00533
MYSDFKQISVADLPG	GTPBP10	191	A4D1E9
SVKVNAGPMAYARAF	DOCK10	2066	Q96BY6
SKINGIEYVPFMNVD	CAPN7	216	Q9Y6W3
NEMGSKYKQFTDPIE	CPLANE1	1086	Q9H799
YLVQVKPMAGDSEQE	COL20A1	56	Q9P218
VGYMTIRFNPDDKSA	FBXO11	341	Q86XK2
GEAALNDPKMYVQTV	CUL1	356	Q13616
MPEQSNDYRVAVFGA	DIRAS2	1	Q96HU8
GVYAMGFNRPSKIQE	DDX19B	106	Q9UMR2
TIKFQEFSPNYMGLE	EFNB1	111	P98172
PEMKTFVDQYGQRDD	CALB1	56	P05937
ERTPFDGTMVYAQNK	DHRS12	191	A0PJE2
YGDAAAQNKPDQVAM	AKNAD1	561	Q5T1N1
QPFGDMTIKDYDNEL	EDEM1	246	Q92611
DPSGQATEFIMNEYK	DYNC1H1	3591	Q14204
VFIDGDYPESMKNNL	KL	331	Q9UEF7
KEFTMNNYFSVGPDA	DGKE	366	P52429
IFEYADGPNAQVMNA	GRIK3	41	Q13003
GYMAPEVVNNEKYTF	GRK4	351	P32298
TIMTNSYEVFKNDGP	DNAH2	801	Q9P225
ANDNAPMFDPQKYEA	CDH3	321	P22223
YSDMFKEINSTANGP	MAP3K19	646	Q56UN5
QVAAKALEMGVFGAY	FTCD	481	O95954
VSLQQSPFEAMFGYK	KRBA2	401	Q6ZNG9
NTGVNLYKVMEAGDF	HMGCLL1	336	Q8TB92
VPNIMETAFYFEQAG	RSPH6A	301	Q9H0K4
SDKYQMSGPIDNAID	POLR3GL	91	Q9BT43
STMINYAQPVKFQGF	PLCB4	566	Q15147
GQEYNFLKMEPGEVN	TLL1	271	O43897
DYGMQEKNPIDHVSF	SAMHD1	506	Q9Y3Z3
KDMDNQIFGAYATHP	NCOA7	836	Q8NI08
ESKSYFNPSNIKEGM	PLCZ1	466	Q86YW0
MFSLGYINPKNSEEQ	NBEA	896	Q8NFP9
AKSDGDVVNNMYEPN	PRDM16	11	Q9HAZ2
NYTRQKIGEEAMFNP	PTCH1	141	Q13635
DVEYENGPQMEFQKV	KIAA1217	1191	Q5T5P2
PQYASQDVVFQDLGM	STARD9	71	Q9P2P6
SKQFSYDGTDKNIPM	PHLDB2	91	Q86SQ0
YETEVEMEKGFNPAQ	NUP160	681	Q12769
TVYADGQAFMVDKPP	SHANK2	1531	Q9UPX8
GMFKGQLTTDQVFPY	ACADVL	76	P49748
YPIAVSGDHENNKMF	ADAM17	436	P78536
DFYNPLVASGQKREM	CLDN4	146	O14493
KAANDAGYFNDEMAP	ACAA2	191	P42765
AGYFNDEMAPIEVKT	ACAA2	196	P42765
MDKEYVGFAALPNQL	SEPTIN1	6	Q8WYJ6
KGVDEDDPVNSAYNM	SPG11	311	Q96JI7
IVADAMQGPAAYSDL	RNF213	2781	Q63HN8
EYITGKFDPQDMDKN	UNC45B	381	Q8IWX7
YFPDMDSSAVVKGTN	SENP5	306	Q96HI0
SGVYEAFVKQPSEME	WWC2	671	Q6AWC2
LYHVEAFKTGPEMQN	MINPP1	246	Q9UNW1
QIEAIAKFDYMGRSP	SRGAP3	746	O43295
EFVEKFMQGQVPYGS	SULT1E1	156	P49888
QESMPFAVVGSDKEY	SEPTIN3	256	Q9UH03
FVDVASMAPLGAQYK	SIDT1	146	Q9NXL6
GPFDSFMVQYKDAQG	TNXB	1286	P22105
FMVQYKDAQGQPQAV	TNXB	1291	P22105
YFIKMGSSVENDNPG	POLK	221	Q9UBT6
QPGQEYNFLKMEAGE	TLL2	271	Q9Y6L7
LQFGVPSDDENFMKY	TTMP	166	Q5BVD1
ESIADMKAFVENYPQ	VPS45	306	Q9NRW7
SPDGRVFQVEYAMKA	PSMA3	16	P25788
KVRPYFNEFQGMDSE	ROBO2	711	Q9HCK4
KVNVSGLDPNAMYSF	TBXT	76	O15178
VKDPQLEVNFYTGMD	LGALS14	31	Q8TCE9
APTAAETDMKQYQGS	TMEM222	26	Q9H0R3
TPDTLAQNEGKAMSY	ZNF507	111	Q8TCN5
FEYMKGIQSDPQALG	TBCD	1006	Q9BTW9
MAFPQFAEKGEQGQY	USP14	181	P54578
KARPGMVSTFEQYQF	PTPRC	1206	P08575
KNLDMDVPYFADVVS	PTS	91	Q03393
ANLEYKTGAFSMPEV	VTCN1	141	Q7Z7D3
KTGAFSMPEVNVDYN	VTCN1	146	Q7Z7D3
SPQQVMGSLVKDYFA	NARF	196	Q9UHQ1
PKDDGNSEIMGYFVQ	MYBPC2	956	Q14324