Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionpattern recognition receptor activity

DMBT1 MARCO

1.07e-043592GO:0038187
GeneOntologyMolecularFunctioncargo receptor activity

DMBT1 MARCO

6.32e-048592GO:0038024
GeneOntologyMolecularFunctiontransition metal ion binding

FLG CA3 NR6A1 DRP2

1.24e-03118994GO:0046914
GeneOntologyMolecularFunctionzinc ion binding

CA3 NR6A1 DRP2

6.08e-0389193GO:0008270
GeneOntologyCellularComponentcollagen-containing extracellular matrix

FLG DMBT1 MARCO

1.21e-0353093GO:0062023
GeneOntologyCellularComponentextracellular matrix

FLG DMBT1 MARCO

2.24e-0365693GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

FLG DMBT1 MARCO

2.26e-0365893GO:0030312
GeneOntologyCellularComponentendocytic vesicle membrane

DMBT1 MARCO

3.52e-0321292GO:0030666
HumanPhenoOpacification of the corneal stroma

GLB1 FLG

3.30e-049322HP:0007759
HumanPhenoAbnormal corneal stroma morphology

GLB1 FLG

4.05e-0410322HP:0011492
HumanPhenoCorneal opacity

GLB1 FLG

3.01e-0328022HP:0007957
HumanPhenoCorneal opacity

GLB1 FLG

3.01e-0328022HP:0000515
HumanPhenoAbnormal fetal morphology

GLB1 FLG

3.69e-0331022HP:0034058
DomainSRCR

DMBT1 MARCO

4.31e-052192PF00530
DomainSR

DMBT1 MARCO

6.16e-052592SM00202
Domain-

DMBT1 MARCO

6.16e-0525923.10.250.10
DomainSRCR_1

DMBT1 MARCO

6.67e-052692PS00420
DomainSRCR_2

DMBT1 MARCO

6.67e-052692PS50287
DomainSRCR-like_dom

DMBT1 MARCO

6.67e-052692IPR017448
DomainSRCR

DMBT1 MARCO

7.20e-052792IPR001190
Domain-

FLG DRP2

6.56e-03261921.10.238.10
DomainEF-hand-dom_pair

FLG DRP2

7.89e-0328792IPR011992
PathwayWP_FATTY_ACIDS_AND_LIPOPROTEINS_TRANSPORT_IN_HEPATOCYTES

DMBT1 MARCO

1.83e-0238182M48063
Pubmed

In Vitro Identification of Histatin 5 Salivary Complexes.

FLG DMBT1

2.08e-05279226544073
InteractionHTN3 interactions

FLG DMBT1

7.66e-053092int:HTN3
InteractionFRMD1 interactions

FLG DMBT1

2.32e-045292int:FRMD1
InteractionTRRAP interactions

FLG CA3 NR6A1 DMBT1

2.52e-0479094int:TRRAP
ToppCellTracheal-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Duct|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CA3 NR6A1 DMBT1

7.02e-0619993527aae1d9d37a50deefc01fc0c064a53673681bd
ToppCellPND07-28-samps-Myeloid-Macrophage-macrophage-A|PND07-28-samps / Age Group, Lineage, Cell class and subclass

DMBT1 MARCO

2.19e-0411292d21cfcb04a27cc9fb74e0c2afa8a8cdfb886ae21
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Macroglial-astrocyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GLB1 DRP2

2.64e-0412392a45d6907c041ad3f3218cd46dccfc25d4bd961cb
ToppCelldroplet-Liver-LIVER_NPC-30m-Epithelial-Hepatocyte_(Midlobular)|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CA3 DMBT1

3.36e-0413992e363c69b58cff8571ca75b91a3d052f9cbccac27
ToppCelldroplet-Liver-LIVER_NPC-30m-Epithelial-hepatocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CA3 DMBT1

3.41e-041409239083c3e288d1878fdc4c798e600fb156daff8a9
ToppCelldroplet-Liver-LIVER_NPC-30m-Epithelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CA3 DMBT1

3.41e-041409206e14a375ea85175c809ff5a0ea16e865ccb4ad5
ToppCellfacs-MAT-Fat-18m-Epithelial-epithelial_cell|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CA3 DMBT1

3.61e-0414492fd852095dcd716ac53b0fd25d83e6f454b2ae794
ToppCellfacs-MAT-Fat-18m-Epithelial-nan|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CA3 DMBT1

3.61e-041449265ffd8a1620b178d995fe8c913871f0b376b896f
ToppCellfacs-MAT-Fat-18m-Epithelial|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CA3 DMBT1

3.61e-0414492e4e148007c772cd163a34fb172e05184f7352a2b
ToppCellfacs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DMBT1 MARCO

3.66e-041459296712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Myeloid-Macrophage-macrophage,_alveolar-Macro_c2-CCL3L1|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PCNX3 MARCO

3.71e-04146921e81ad3d6d5d5ad2f0176d2a9593a954d38fa294
ToppCellPND01-03-samps-Myeloid-Macrophage-macrophage-B|PND01-03-samps / Age Group, Lineage, Cell class and subclass

DMBT1 MARCO

4.02e-04152925ce8920aedd39a4daf7082153b5e213707c14227
ToppCellIIH-CD4-CD4_Treg|IIH / Condition, Cell_class and T cell subcluster

CA3 DRP2

4.07e-041539228fb5d9f66f58741a5d43df004f80da3d910682e
ToppCelltumor_Lymph_Node_/_Brain-T/NK_cells-Naive_CD8+_T|T/NK_cells / Location, Cell class and cell subclass

NR6A1 DMBT1

4.18e-04155921020da8a2c30384d962fa204a030299fdfcbbf98
ToppCellGoblet|World / Class top

CA3 DMBT1

4.29e-0415792b352aa37d662629db6a9c6def9ee6d7c49a9071c
ToppCellGoblet-gob-1|World / Class top

CA3 DMBT1

4.40e-041599262d4ca2b538382419252e306d7a789b64420fb18
ToppCell10x3'2.3-week_12-13-Myeloid_DC-DC-DC3|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

GLB1 MARCO

4.51e-041619239030380e04f57f8e7de231577ec3177e1b6490d
ToppCelldroplet-Pancreas-Exocrine-21m-Epithelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DMBT1 DRP2

4.56e-0416292922ecea81063095b8dd9ac9f9792bf551edbb848
ToppCellfacs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DMBT1 MARCO

4.56e-0416292bf886e22ff2a20353499004b53f25fb9e6574896
ToppCell343B-Myeloid-Macrophage-SPP1+_Macrophage|343B / Donor, Lineage, Cell class and subclass (all cells)

MARCO ZNF285

4.68e-0416492057ca87847373eff7fe97dd9f4358509e66ca4c3
ToppCelldroplet-Pancreas-Exocrine-21m|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DMBT1 DRP2

4.73e-0416592c17e00ec9dbe30fcded65a461231dbb13665ddac
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

CA3 NR6A1

4.79e-0416692c20479fe7a4306320d7f26e78bf956225f00f35a
ToppCell3'-Distal_airway-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.4.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MARCO ZNF285

4.90e-0416892eba865465feb0f42055bb8f98946050eeb03d177
ToppCell390C-Myeloid-Macrophage-SPP1+_Macrophage_4|390C / Donor, Lineage, Cell class and subclass (all cells)

NR6A1 MARCO

5.02e-0417092439167e44a1bd5ac8e1e457351dd202ec968db46
ToppCell3'-Distal_airway-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.3.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MARCO ZNF285

5.38e-041769276fdf211bce101e83a27d822cb399487bd107027
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.3.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GLB1 MARCO

5.50e-04178920b398656f26c4061b11ccf98908d0e2e1367585a
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

CA3 NR6A1

5.50e-0417892f5ed4a6e3eb8056b1be1fb311021710c95bdf888
ToppCellnormal_Pleural_Fluid-Myeloid_cells-mo-Mac|normal_Pleural_Fluid / Location, Cell class and cell subclass

DMBT1 MARCO

5.56e-0417992cd3c58e044f5a38e815313a1636153d81a592fce
ToppCelldroplet-Mammary_Gland-nan-18m-Endothelial-nan|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CA3 MARCO

5.69e-04181922e15c46e8260bb04d8264478c19a707221996026
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Myeloid-Monocytic-Nonclassical_Monocyte-Mono_c4-CD14-CD16|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

FLG MARCO

5.81e-0418392745271bfe15e94a58157cd97d771e610f964341b
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

CA3 NR6A1

5.88e-0418492102105ae1a5ef6d42a43f6d9b00f12ed0690ddb7
ToppCell3'-GW_trimst-1.5-SmallIntestine-Epithelial-neuro-epithelial-EECs|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CA3 DMBT1

5.94e-0418592d42f6722a6771752cd744146a09e2ead9b7252bc
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|Children_(3_yrs) / Lineage, Cell type, age group and donor

CA3 NR6A1

5.94e-041859298b8ee42b89d97e4c9db01740e0c193503c68f2c
ToppCellfacs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea-|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CA3 DRP2

6.00e-0418692bdc87e4631a8ea73e262e541aa84a28f24c94b00
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.4.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GLB1 MARCO

6.00e-0418692cb7df8da6478b96955f3ef1394a0655ec8061bba
ToppCellhuman_hepatoblastoma-Tumor_cells-T2|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

CA3 NR6A1

6.07e-0418792f3e37c18ac6471c7992609bbddfa4975571c815c
ToppCellEpithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|World / Lineage, Cell type, age group and donor

CA3 NR6A1

6.07e-041879281cc8435b2704a9a8287b3f54acaae0f11dd4ac7
ToppCell10x5'-GI_large-bowel-Myeloid_Monocytic|GI_large-bowel / Manually curated celltypes from each tissue

MARCO ZNF285

6.13e-0418892d0045fdda757d191dabc7853f6a6e99c0e97d93d
ToppCell10x5'-GI_large-bowel-Myeloid_Monocytic-Classical_monocytes|GI_large-bowel / Manually curated celltypes from each tissue

MARCO ZNF285

6.13e-04188920bcf04aa47738f43c1a87dae5dc487738ee86f8c
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_proliferating-Alveolar_macrophage_proliferating_L.1.0.7.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MARCO DRP2

6.33e-0419192d6e158f16a183c9203c057192342e9b83e79bc89
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_proliferating|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MARCO DRP2

6.33e-04191927cb5c6f2cf27f3503d1b313e402a7410dfe6473e
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-Mono-Mono_anti-infl-C|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

GLB1 MARCO

6.46e-041939279a95ac4f46abee00e03700c10cdb00c4507ea76
ToppCellAT2|World / shred by cell class for parenchyma

GLB1 DMBT1

6.53e-0419492e773f5ef3abce7113a6b7cc7cbe68de873d4a17f
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GLB1 MARCO

6.66e-0419692aae79eafe5bc2c7de16958994a2fe97439d7bea1
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GLB1 MARCO

6.66e-04196922793ad692d49b3ee78a5cd2d8e0220bf5188a686
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.4.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GLB1 MARCO

6.66e-0419692eb7d6bbfb766cdeaf5fe0f0bb66a5f491fd5ef26
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.4.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GLB1 MARCO

6.66e-0419692173d2c38a01c9ae1c50657d5fc383238aed4aacb
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.4.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GLB1 MARCO

6.73e-04197924f022bae7af2ca23689cc0d35046a7e23dba6e9c
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.4.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GLB1 MARCO

6.73e-041979269671ed173057a67265ac39ed03fbd57dbd22c5c
ToppCell(7)_Epithelial_cells-(7)_Epithelial-B_(AT2)|(7)_Epithelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)

GLB1 DMBT1

6.80e-0419892391f59e232269f6ae9f8792d21a60ad534e03c4d
ToppCell(7)_Epithelial_cells-(7)_Epithelial-D_(AT2)|(7)_Epithelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)

GLB1 MARCO

6.80e-0419892963b7ff8c5322d9290bbaf42137bb8fdd0672db9
ToppCellBronchial-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Duct|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CA3 DRP2

6.80e-04198921fe60443c11d34b6d2671af8f06e0dedc8d1558b
ToppCelldistal-Hematologic-Alveolar_Macrophage-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

GLB1 MARCO

6.87e-04199922918967da22602404c767d948fed6c4754e53518
ToppCelldistal-3-Hematologic-Alveolar_Macrophage|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

GLB1 MARCO

6.87e-0419992f57ba6c711e16fe46f8ddc70223576906b3a710b
Drugindigo dye

GLB1 CA3

1.08e-044092CID005318432
DrugCTK8F9183

GLB1 CA3

2.04e-045592CID010176637
Drugfumonisin B1

CA3 DMBT1 MARCO

2.21e-0432293ctd:C056933
DrugAC1L8OYS

CA3 MARCO

4.11e-047892CID000430234
DrugAMPCPR

GLB1 CA3

8.90e-0411592CID000446724
Drugalpha-methyl-D-mannoside

GLB1 MARCO

9.05e-0411692CID000002108
DrugOzone

CA3 DMBT1 MARCO DRP2

9.77e-04127394ctd:D010126
Drugdiphenyl

GLB1 CA3

1.17e-0313292CID000007095
DiseaseEczema, Infantile

GLB1 FLG

5.18e-053692C0086196
DiseaseDermatitis, Atopic

GLB1 FLG

5.18e-053692C0011615
DiseaseContact hypersensitivity

GLB1 FLG

2.03e-047192C0162351
DiseaseContact Dermatitis

GLB1 FLG

2.03e-047192C0011616
DiseaseInhalant adrenergic use measurement

GLB1 MARCO

3.72e-049692EFO_0009941
Diseaserespiratory system disease

GLB1 FLG

8.44e-0414592EFO_0000684
Diseaseatopic asthma

GLB1 FLG

1.58e-0319992EFO_0010638
Diseaseatopic eczema

GLB1 FLG

2.51e-0325292EFO_0000274
Diseaseallergic disease

GLB1 FLG

2.63e-0325892MONDO_0005271
DiseaseEczema

GLB1 FLG

3.77e-0331092HP_0000964
Diseasechildhood onset asthma

GLB1 FLG

4.36e-0333492MONDO_0005405
Diseasebone density

DMBT1 MARCO

5.84e-0338892EFO_0003923
Diseaseasthma

GLB1 FLG

2.07e-0275192MONDO_0004979

Protein segments in the cluster

PeptideGeneStartEntry
HWGSSDDHGSEHTVD

CA3

96

P07451
SGSHHHEASSWADSS

FLG

2206

P20930
GDGSRHSWSHHHEAS

FLG

3496

P20930
HSWSHHHEASTQADS

FLG

3501

P20930
DSGHHDEAWAHNSSN

GLB1

531

P16278
ANGAWDRHSHSSSFH

PCNX3

696

Q9H6A9
NSWGHHDCSHEEDAG

MARCO

501

Q9UEW3
HNGWLSHNCGHHEDA

DMBT1

1461

Q9UGM3
CHDWQAADQFHHSSS

DRP2

16

Q13474
ANHWSNHGDSDHSSP

NR6A1

166

Q15406
HDDSLSWTSCDHHES

ZNF285

181

Q96NJ3