Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	benzodiazepine receptor binding	RIMBP3 RIMBP3C RIMBP3B	3.41e-06	5	141	3	GO:0030156
GeneOntologyMolecularFunction	guanyl-nucleotide exchange factor activity	RAPGEF6 DOCK11 FRMD7 DENND4C MADD FBXO8 SBF1 DOCK7 BCAR3 DOCK6	5.82e-06	231	141	10	GO:0005085
GeneOntologyMolecularFunction	actin filament binding	FLNC SHROOM3 MYO1C SPTBN1 TRIOBP ACTR3 ERMN TLN1 PLEC	3.45e-05	227	141	9	GO:0051015
GeneOntologyMolecularFunction	structural constituent of cytoskeleton	TUBG2 SPTBN1 ACTA1 ACTR3 TUBG1 TLN1 PLEC	3.86e-05	130	141	7	GO:0005200
GeneOntologyMolecularFunction	toxin transmembrane transporter activity	LRP6 LRP5 SLC29A4	7.24e-05	12	141	3	GO:0019534
GeneOntologyMolecularFunction	ligase activity	CAD ACACA TPGS1 UBE2L5 CTPS1 QARS1 ACSL5	2.40e-04	174	141	7	GO:0016874
GeneOntologyMolecularFunction	myosin binding	ACTA1 TRIOBP ACTC1 ADGRV1 GCSAM	3.41e-04	85	141	5	GO:0017022
GeneOntologyMolecularFunction	enzyme regulator activity	RAPGEF6 ERCC4 DOCK11 FRMD7 CAST DGKZ ADGRV1 GRM5 DENND4C MADD CCNA2 FBXO8 SBF1 UBE2L3 PDP1 TIMM50 DOCK7 NPRL3 LRP6 BCAR3 QARS1 DOCK6	3.90e-04	1418	141	22	GO:0030234
GeneOntologyMolecularFunction	ankyrin binding	FLNC SPTBN1 PLEC	5.50e-04	23	141	3	GO:0030506
GeneOntologyMolecularFunction	nucleoside-triphosphatase regulator activity	RAPGEF6 DOCK11 FRMD7 DENND4C MADD FBXO8 SBF1 DOCK7 NPRL3 BCAR3 DOCK6	9.61e-04	507	141	11	GO:0060589
GeneOntologyMolecularFunction	GTPase regulator activity	RAPGEF6 DOCK11 FRMD7 DENND4C MADD FBXO8 SBF1 DOCK7 NPRL3 BCAR3 DOCK6	9.61e-04	507	141	11	GO:0030695
GeneOntologyCellularComponent	focal adhesion	FLNC TRIOBP ACTC1 ACTR3 AKAP12 TLN1 DOCK7 PLEC BCAR3 ALKBH6 MAP4K4 ALOX15B	3.67e-05	431	141	12	GO:0005925
GeneOntologyCellularComponent	cell-substrate junction	FLNC TRIOBP ACTC1 ACTR3 AKAP12 TLN1 DOCK7 PLEC BCAR3 ALKBH6 MAP4K4 ALOX15B	4.79e-05	443	141	12	GO:0030055
GeneOntologyCellularComponent	Wnt-Frizzled-LRP5/6 complex	LRP6 LRP5	4.46e-04	5	141	2	GO:1990851
GeneOntologyCellularComponent	somatodendritic compartment	CHL1 CAD FRMD7 TPGS1 PALMD RET KCNIP3 KCNIP2 GRM5 GRM6 AKAP12 WDR47 ERMN TH NSMF KCNJ2 EIF4B LRP6 PLEC	6.04e-04	1228	141	19	GO:0036477
GeneOntologyCellularComponent	stereocilium membrane	MYO1C ADGRV1	6.66e-04	6	141	2	GO:0060171
GeneOntologyCellularComponent	manchette	RIMBP3 RIMBP3C RIMBP3B	8.70e-04	28	141	3	GO:0002177
GeneOntologyCellularComponent	anchoring junction	FLNC SHROOM3 TRIOBP ACTC1 ITGAL ACTR3 AKAP12 TJP1 KCNJ2 TLN1 DOCK7 PLEC BCAR3 ALKBH6 MAP4K4 ALOX15B	9.15e-04	976	141	16	GO:0070161
GeneOntologyCellularComponent	supramolecular fiber	FLNC SHROOM3 MYO1C TUBG2 SPTBN1 ACTA1 ACTC1 TPGS1 CASQ1 EIF6 ACTR3 TUBG1 WDR47 EFHC2 NEK2 PARP4 PLEC CTPS1	9.87e-04	1179	141	18	GO:0099512
GeneOntologyCellularComponent	supramolecular polymer	FLNC SHROOM3 MYO1C TUBG2 SPTBN1 ACTA1 ACTC1 TPGS1 CASQ1 EIF6 ACTR3 TUBG1 WDR47 EFHC2 NEK2 PARP4 PLEC CTPS1	1.07e-03	1187	141	18	GO:0099081
Domain	DUF3398	DOCK11 DOCK7 DOCK6	7.94e-06	6	139	3	PF11878
Domain	DOCK_C/D_N	DOCK11 DOCK7 DOCK6	7.94e-06	6	139	3	IPR021816
Domain	LRP5/6	LRP6 LRP5	5.50e-05	2	139	2	IPR017049
Domain	Gamma_tubulin	TUBG2 TUBG1	5.50e-05	2	139	2	IPR002454
Domain	DHR-1_domain	DOCK11 DOCK7 DOCK6	6.37e-05	11	139	3	IPR027007
Domain	DHR_2	DOCK11 DOCK7 DOCK6	6.37e-05	11	139	3	PS51651
Domain	DHR_1	DOCK11 DOCK7 DOCK6	6.37e-05	11	139	3	PS51650
Domain	DHR-2	DOCK11 DOCK7 DOCK6	6.37e-05	11	139	3	PF06920
Domain	DOCK	DOCK11 DOCK7 DOCK6	6.37e-05	11	139	3	IPR026791
Domain	DOCK_C	DOCK11 DOCK7 DOCK6	6.37e-05	11	139	3	IPR010703
Domain	DOCK-C2	DOCK11 DOCK7 DOCK6	6.37e-05	11	139	3	PF14429
Domain	DHR-2	DOCK11 DOCK7 DOCK6	6.37e-05	11	139	3	IPR027357
Domain	SPOC_met	RBM15B SPEN	1.64e-04	3	139	2	IPR010912
Domain	DENN	DENND4C MADD SBF1	2.10e-04	16	139	3	SM00799
Domain	DENN	DENND4C MADD SBF1	2.10e-04	16	139	3	PF02141
Domain	dDENN	DENND4C MADD SBF1	2.10e-04	16	139	3	PF03455
Domain	UDENN	DENND4C MADD SBF1	2.10e-04	16	139	3	PS50946
Domain	DDENN	DENND4C MADD SBF1	2.10e-04	16	139	3	PS50947
Domain	dDENN	DENND4C MADD SBF1	2.10e-04	16	139	3	SM00801
Domain	dDENN_dom	DENND4C MADD SBF1	2.10e-04	16	139	3	IPR005112
Domain	uDENN_dom	DENND4C MADD SBF1	2.10e-04	16	139	3	IPR005113
Domain	DENN	DENND4C MADD SBF1	2.10e-04	16	139	3	PS50211
Domain	DENN_dom	DENND4C MADD SBF1	2.10e-04	16	139	3	IPR001194
Domain	Actin/actin-like_CS	ACTA1 ACTC1 ACTR3	3.03e-04	18	139	3	IPR020902
Domain	SPOC	RBM15B SPEN	3.27e-04	4	139	2	PS50917
Domain	ACTINS_ACT_LIKE	ACTA1 ACTC1 ACTR3	3.58e-04	19	139	3	PS01132
Domain	-	RBM15B SPEN	5.42e-04	5	139	2	2.40.290.10
Domain	GATase	CAD CTPS1	5.42e-04	5	139	2	PF00117
Domain	CPSASE_1	CAD ACACA	5.42e-04	5	139	2	PS00866
Domain	SPOC-like_C_dom	RBM15B SPEN	5.42e-04	5	139	2	IPR016194
Domain	ACTININ_2	FLNC SPTBN1 PLEC	6.41e-04	23	139	3	PS00020
Domain	ACTININ_1	FLNC SPTBN1 PLEC	6.41e-04	23	139	3	PS00019
Domain	ADAM_spacer1	ADAMTS1 ADAMTS6 ADAMTSL2	6.41e-04	23	139	3	IPR010294
Domain	Actinin_actin-bd_CS	FLNC SPTBN1 PLEC	6.41e-04	23	139	3	IPR001589
Domain	ADAM_spacer1	ADAMTS1 ADAMTS6 ADAMTSL2	6.41e-04	23	139	3	PF05986
Domain	Peptidase_M12B_ADAM-TS	ADAMTS1 ADAMTS6 ADAMTSL2	7.28e-04	24	139	3	IPR013273
Domain	LipOase_mml	ALOXE3 ALOX15B	8.09e-04	6	139	2	IPR001885
Domain	LIPOXYGENASE_1	ALOXE3 ALOX15B	8.09e-04	6	139	2	PS00711
Domain	LipOase_C	ALOXE3 ALOX15B	8.09e-04	6	139	2	IPR013819
Domain	SPOC_C	RBM15B SPEN	8.09e-04	6	139	2	IPR012921
Domain	GATASE_TYPE_1	CAD CTPS1	8.09e-04	6	139	2	PS51273
Domain	LIPOXYGENASE_2	ALOXE3 ALOX15B	8.09e-04	6	139	2	PS00081
Domain	LipOase_Fe_BS	ALOXE3 ALOX15B	8.09e-04	6	139	2	IPR020833
Domain	LipOase_CS	ALOXE3 ALOX15B	8.09e-04	6	139	2	IPR020834
Domain	GATASE	CAD CTPS1	8.09e-04	6	139	2	IPR017926
Domain	Lipoxygenase	ALOXE3 ALOX15B	8.09e-04	6	139	2	PF00305
Domain	CPSASE_2	CAD ACACA	8.09e-04	6	139	2	PS00867
Domain	LIPOXYGENASE_3	ALOXE3 ALOX15B	8.09e-04	6	139	2	PS51393
Domain	LipOase	ALOXE3 ALOX15B	8.09e-04	6	139	2	IPR000907
Domain	SPOC	RBM15B SPEN	8.09e-04	6	139	2	PF07744
Domain	CbamoylP_synth_lsu-like_ATP-bd	CAD ACACA	1.13e-03	7	139	2	IPR005479
Domain	BC-like_N	CAD ACACA	1.13e-03	7	139	2	IPR005481
Domain	CPSase_L_D2	CAD ACACA	1.13e-03	7	139	2	PF02786
Domain	Biotin_carb_N	CAD ACACA	1.13e-03	7	139	2	PF00289
Domain	GPCR_3_mtglu_rcpt	GRM5 GRM6	1.50e-03	8	139	2	IPR000162
Domain	Calx_beta	FRAS1 ADGRV1	1.50e-03	8	139	2	SM00237
Domain	ACTINS_1	ACTA1 ACTC1	1.50e-03	8	139	2	PS00406
Domain	Actin	ACTA1 ACTC1 ACTR3	1.56e-03	31	139	3	IPR004000
Domain	Actin	ACTA1 ACTC1 ACTR3	1.56e-03	31	139	3	PF00022
Domain	ACTIN	ACTA1 ACTC1 ACTR3	1.56e-03	31	139	3	SM00268
Domain	Calx_beta	FRAS1 ADGRV1	1.91e-03	9	139	2	IPR003644
Domain	Calx-beta	FRAS1 ADGRV1	1.91e-03	9	139	2	PF03160
Domain	-	CAD CTPS1	2.38e-03	10	139	2	3.40.50.880
Domain	Class_I_gatase-like	CAD CTPS1	3.46e-03	12	139	2	IPR029062
Domain	SH3_2	RIMBP3 TJP1 RIMBP3C RIMBP3B	3.89e-03	86	139	4	PF07653
Domain	SH3_2	RIMBP3 TJP1 RIMBP3C RIMBP3B	3.89e-03	86	139	4	IPR011511
Domain	-	CAD ACACA	4.06e-03	13	139	2	3.40.50.20
Domain	NCD3G	GRM5 GRM6	4.06e-03	13	139	2	PF07562
Domain	GPCR_3_9-Cys_dom	GRM5 GRM6	4.06e-03	13	139	2	IPR011500
Domain	Recoverin	KCNIP3 KCNIP2	4.06e-03	13	139	2	IPR028846
Domain	ATP_GRASP	CAD ACACA	4.72e-03	14	139	2	PS50975
Domain	PLAC	ADAMTS6 ADAMTSL2	4.72e-03	14	139	2	PF08686
Domain	ATP-grasp	CAD ACACA	4.72e-03	14	139	2	IPR011761
Domain	PreATP-grasp_dom	CAD ACACA	4.72e-03	14	139	2	IPR016185
Domain	uDENN	MADD SBF1	4.72e-03	14	139	2	SM00800
Domain	Ldl_recept_b	LRP6 LRP5	4.72e-03	14	139	2	PF00058
Domain	LDLRB	LRP6 LRP5	4.72e-03	14	139	2	PS51120
Domain	GPCR_3_CS	GRM5 GRM6	4.72e-03	14	139	2	IPR017979
Domain	uDENN	MADD SBF1	5.42e-03	15	139	2	PF03456
Domain	LY	LRP6 LRP5	5.42e-03	15	139	2	SM00135
Domain	-	CAD ACACA	5.42e-03	15	139	2	3.30.1490.20
Domain	LDLR_classB_rpt	LRP6 LRP5	5.42e-03	15	139	2	IPR000033
Domain	Actin_CS	ACTA1 ACTC1	6.16e-03	16	139	2	IPR004001
Domain	ACTINS_2	ACTA1 ACTC1	6.95e-03	17	139	2	PS00432
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	AMPD2 SHROOM3 RAPGEF6 EDC3 ACACA DOCK11 SPTBN1 RFX7 VIRMA DENND4C MADD CEP350 SBF1 FAM171A2 TJP1 EIF4B TIMM50 DOCK7 PLEC MTREX DOCK6 MAP4K4 ANKS1A	8.46e-13	861	141	23	36931259
Pubmed	A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.	FLNC EDC3 ACACA DOCK11 CAST TRIOBP EIF6 ACTR3 AKAP12 CEP350 PARP4 RBM22 SBF1 TJP1 TLN1 EIF4B DOCK7 PLEC QARS1 SPEN	1.65e-11	724	141	20	36232890
Pubmed	Tumor suppressor BAP1 nuclear import is governed by transportin-1.	FLNC CAD DDX17 ACACA ADAMTS1 SPTBN1 NIPSNAP1 CAST ACTC1 IDI1 MORC4 EIF6 ACTR3 TUBG1 AKAP12 UBE2L3 TLN1 EIF4B NEMF PANK4 DOCK7 PLEC CTPS1 QARS1	4.37e-11	1149	141	24	35446349
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	FLNC TEAD2 FRAS1 SHROOM3 RAPGEF6 ACACA POLG EIF6 ELAC2 TUBG1 MADD MAP3K5 CELSR3 SBF1 TLN1 NPRL3 LRP5 PLEC SLC45A1 DOCK6 ALKBH6 SPEN DHX34	1.25e-10	1105	141	23	35748872
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	AMPD2 SHROOM3 RAPGEF6 EDC3 DOCK11 ACTA1 NIPSNAP1 DENND4C TJP1 DOCK7 MTREX QARS1 DOCK6 MAP4K4 ANKS1A	4.63e-10	446	141	15	24255178
Pubmed	Mapping the MOB proteins' proximity network reveals a unique interaction between human MOB3C and the RNase P complex.	CAD ACACA MYO1C DOCK11 PEG10 ACTA1 ACTR3 TLN1 DOCK7 MTREX CTPS1 QARS1 DOCK6 MAP4K4	1.05e-09	399	141	14	37536630
Pubmed	Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.	AMPD2 CAD DDX17 ACACA SPTBN1 ACTA1 NIPSNAP1 CAST MRPL28 EIF6 ELAC2 TUBG1 RBM22 UBE2L3 TJP1 MORF4L1 TLN1 EIF4B NEMF TIMM50 PLEC MTREX CTPS1 QARS1	2.79e-09	1415	141	24	28515276
Pubmed	CDK7/GRP78 signaling axis contributes to tumor growth and metastasis in osteosarcoma.	FLNC DDX17 MYO1C SPTBN1 ACTA1 NIPSNAP1 IDI1 EIF6 ACTR3 EIF4B TIMM50 PWWP3A PLEC SPEN	8.03e-09	468	141	14	36042349
Pubmed	LGALS3BP regulates centriole biogenesis and centrosome hypertrophy in cancer cells.	CAD DDX17 ADAMTS1 SPTBN1 ACTA1 NIPSNAP1 TPGS1 TUBG1 AKAP12 CCNA2 CEP350 NEK2 SBF1 TIMM50 DOCK7 CTPS1	8.09e-09	639	141	16	23443559
Pubmed	A Novel Mouse Model for Cilia-Associated Cardiovascular Anomalies with a High Penetrance of Total Anomalous Pulmonary Venous Return.	TUBG2 ACTA1 ACTC1 TUBG1	8.97e-09	7	141	4	30289203
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	AMPD2 SHROOM3 CAD DOCK11 SPTBN1 TRIOBP DGKZ GRM5 VIRMA AKAP12 MAP3K5 WDR47 SBF1 FAM171A2 TJP1 MORF4L1 DOCK7 MAP4K4 ANKS1A	1.40e-08	963	141	19	28671696
Pubmed	N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.	FLNC AMPD2 MYO1C PEG10 SPTBN1 TRIOBP TUBG1 AKAP12 TJP1 TLN1 DBR1 PLEC	3.04e-08	360	141	12	33111431
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	AMPD2 CAD DDX17 ACACA SPTBN1 NIPSNAP1 TRIOBP PALMD GRM5 TUBG1 MADD WDR47 FAM171A2 UBE2L3 TJP1 EIF4B TIMM50 DOCK7 PLEC MAP4K4	3.86e-08	1139	141	20	36417873
Pubmed	A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.	RAPGEF6 EDC3 DDX17 NIPSNAP1 DGKZ PALMD ACTR3 TUBG1 DENND4C MADD CEP350 TJP1 EIF4B DOCK7 KATNIP DBR1 MTREX DOCK6 MAP4K4	4.57e-08	1038	141	19	26673895
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	FLNC CAD ACACA MYO1C SPTBN1 VIRMA EIF6 ACTR3 SBF1 TJP1 TLN1 DOCK7 PLEC MTREX SPEN	7.49e-08	653	141	15	22586326
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	FLNC CAD DDX17 MYO1C SPTBN1 ACTA1 NIPSNAP1 TPGS1 DGKZ GRM5 VIRMA ACTR3 MADD WDR47 ERMN SBF1 TJP1 TLN1 EIF4B DOCK7 FGG PLEC	7.80e-08	1431	141	22	37142655
Pubmed	A dual role for planar cell polarity genes in ciliated cells.	TUBG2 TUBG1 CELSR3 TJP1	8.36e-08	11	141	4	25024228
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	FLNC CAD DDX17 SPTBN1 ACTA1 TRIOBP TUBG1 RBM22 SBF1 TJP1 MORF4L1 NEMF DOCK7 RBM15B SRPX PLEC DOCK6 SPEN MAP4K4	8.72e-08	1082	141	19	38697112
Pubmed	A high-throughput approach for measuring temporal changes in the interactome.	PRUNE2 FLNC AMPD2 DDX17 ACACA PEG10 SPTBN1 ACTA1 CAST USP25 EIF6 ACTR3 ELAC2 TUBG1 AKAP12 TLN1 EIF4B PANK4 PLEC CTPS1 QARS1 ANKS1A	1.04e-07	1455	141	22	22863883
Pubmed	LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.	CAD DDX17 ACACA MYO1C PARP4 SBF1 DOCK7 PLEC DOCK6	1.52e-07	202	141	9	33005030
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	CAD DDX17 MYO1C SPTBN1 ACTC1 MRPL28 VIRMA EIF6 ACTR3 RBM22 TJP1 EIF4B TIMM50 DOCK7 RBM15B PLEC MTREX CTPS1 QARS1 SPEN	1.89e-07	1257	141	20	36526897
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	FLNC CAD DDX17 ACTA1 NIPSNAP1 ACTC1 EIF6 ACTR3 CEP350 TJP1 TLN1 TIMM50 DOCK7 PLEC MTREX QARS1 SPEN MAP4K4	1.93e-07	1024	141	18	24711643
Pubmed	Lrp5/6 are required for cerebellar development and for suppressing TH expression in Purkinje cells via β-catenin.	TH LRP6 LRP5	2.60e-07	4	141	3	26772978
Pubmed	RIM-BP3 is a manchette-associated protein essential for spermiogenesis.	RIMBP3 RIMBP3C RIMBP3B	2.60e-07	4	141	3	19091768
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	ADAMTS1 TUBG2 PEG10 POLG SPTBN1 USP25 TRIOBP MADD WDR47 CEP350 RBM22 NSMF CELSR3 TJP1 MORF4L1 NEMF PLEC QARS1 ALKBH6 MAP4K4	2.67e-07	1285	141	20	35914814
Pubmed	Two-Dimensional Fractionation Method for Proteome-Wide Cross-Linking Mass Spectrometry Analysis.	FLNC DDX17 MYO1C SPTBN1 NIPSNAP1 ACTC1 DGKZ HSP90AA5P ACTR3 ELAC2 TLN1 EIF4B LRP5 PLEC QARS1 MAP4K4	3.78e-07	847	141	16	35235311
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	SHROOM3 EDC3 ACACA CAST IFT46 EIF6 ACTR3 CEP350 RIMBP3 TJP1 TLN1 EIF4B TIMM50 PLEC MAP4K4 ANKS1A	4.15e-07	853	141	16	28718761
Pubmed	A neomorphic cancer cell-specific role of MAGE-A4 in trans-lesion synthesis.	FLNC MYO1C SPTBN1 ACTA1 ACTR3 TJP1 TIMM50	5.61e-07	118	141	7	27377895
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	FLNC CAD DDX17 ACACA MYO1C SPTBN1 NIPSNAP1 EIF6 ACTR3 ELAC2 WDR47 RBM22 SBF1 TLN1 TIMM50 PLEC MTREX CTPS1 QARS1 DHX34	6.00e-07	1353	141	20	29467282
Pubmed	Primary cilia dynamics instruct tissue patterning and repair of corneal endothelium.	TUBG2 TUBG1 TJP1	6.48e-07	5	141	3	21285373
Pubmed	Structure and evolution of RIM-BP genes: identification of a novel family member.	RIMBP3 RIMBP3C RIMBP3B	6.48e-07	5	141	3	17855024
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	PRUNE2 SHROOM3 ACACA POLG CAST TRIOBP RNF213 TPGS1 ADGRV1 KCNIP3 KCNIP2 SHC2 TJP1 NEMF PANK4 LRP5 KATNIP DOCK6 VPS13B CREB3L2 ANKS1A	6.51e-07	1489	141	21	28611215
Pubmed	CYLD Regulates Centriolar Satellites Proteostasis by Counteracting the E3 Ligase MIB1.	CAD TUBG1 CEP350 PARP4 TLN1 PLEC MTREX CTPS1	8.44e-07	182	141	8	31067453
Pubmed	Impaired plasma membrane localization of ubiquitin ligase complex underlies 3-M syndrome development.	PRUNE2 SHROOM3 CAD ACTC1 ERMN NSMF NEMF TIMM50 RBM15B PLEC MTREX DOCK6	9.37e-07	496	141	12	31343991
Pubmed	A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.	FLNC PEG10 SPTBN1 ACTA1 ACTC1 AKAP12 MAP3K5 PARP4 MORF4L1 TLN1 EIF4B PLEC	9.57e-07	497	141	12	23414517
Pubmed	BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.	CAD EDC3 DDX17 SPTBN1 DENND4C AKAP12 TLN1 EIF4B DOCK7 LRP6 CTPS1 QARS1 MAP4K4 ANKS1A	1.24e-06	708	141	14	39231216
Pubmed	A novel centrosomal ring-finger protein, dorfin, mediates ubiquitin ligase activity.	TUBG2 TUBG1 UBE2L3	1.29e-06	6	141	3	11237715
Pubmed	The ubiquitin-specific protease USP25 interacts with three sarcomeric proteins.	FLNC ACTA1 USP25	1.29e-06	6	141	3	16501887
Pubmed	DOCK7 interacts with TACC3 to regulate interkinetic nuclear migration and cortical neurogenesis.	TUBG2 TUBG1 DOCK7	1.29e-06	6	141	3	22842144
Pubmed	Cytoplasmic Cl- couples membrane remodeling to epithelial morphogenesis.	TUBG2 TUBG1 TJP1	1.29e-06	6	141	3	29229864
Pubmed	Human transcription factor protein interaction networks.	TEAD2 CAD ERCC4 EDC3 MYO1C PEG10 SPTBN1 TPGS1 MRPL28 MORC4 RFX7 INO80D EIF6 ACTR3 CCNA2 MORF4L1 TIMM50 LRP6 QARS1 SPEN	1.39e-06	1429	141	20	35140242
Pubmed	ISG15 Connects Autophagy and IFN-γ-Dependent Control of Toxoplasma gondii Infection in Human Cells.	CAD DDX17 MYO1C ACTC1 RNF213 TJP1 TIMM50 PLEC QARS1	1.62e-06	268	141	9	33024031
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	SHROOM3 TRIOBP ADGRV1 CELSR3 SBF1 SETD7 MTREX DOCK6 DHX34 MAP4K4 ANKS1A ZNF646	1.83e-06	529	141	12	14621295
Pubmed	Quantitative Proteomics Reveals Dynamic Interactions of the Minichromosome Maintenance Complex (MCM) in the Cellular Response to Etoposide Induced DNA Damage.	FLNC CAD DDX17 MYO1C ACTA1 ACTC1 RNF213 ACTR3 UBE2D4 UBE2L3 TLN1 TIMM50 PLEC CTPS1 QARS1	1.89e-06	844	141	15	25963833
Pubmed	PCP auto count: a novel Fiji/ImageJ plug-in for automated quantification of planar cell polarity and cell counting.	TUBG2 TUBG1 TJP1	2.26e-06	7	141	3	38827526
Pubmed	Asymmetric segregation of the double-stranded RNA binding protein Staufen2 during mammalian neural stem cell divisions promotes lineage progression.	TUBG2 TUBG1 TJP1	2.26e-06	7	141	3	22902295
Pubmed	Mice lacking factor VII develop normally but suffer fatal perinatal bleeding.	ACTA1 ACTC1 FGG	2.26e-06	7	141	3	9384381
Pubmed	Acetylation of ELF5 suppresses breast cancer progression by promoting its degradation and targeting CCND1.	FRAS1 EDC3 DDX17 ACACA ITGAL EIF6 TLN1 NEMF PANK4 TIMM50 DOCK7 DBR1 MTREX	2.81e-06	653	141	13	33742100
Pubmed	Neural tube defects by NUAK1 and NUAK2 double mutation.	SHROOM3 TUBG2 TUBG1 TJP1	3.06e-06	25	141	4	22689267
Pubmed	Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.	CAD DDX17 ACACA MYO1C SPTBN1 RFX7 EIF6 ACTR3 ELAC2 TUBG1 RBM22 TJP1 TLN1 EIF4B NEMF NPRL3 MTREX QARS1	3.22e-06	1247	141	18	27684187
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	RAPGEF6 ACACA MYO1C SPTBN1 CAST RFX7 VIRMA EIF4B RBM15B PLEC CTPS1 SPEN MAP4K4 ANKS1A	3.48e-06	774	141	14	15302935
Pubmed	Cortactin localization to sites of actin assembly in lamellipodia requires interactions with F-actin and the Arp2/3 complex.	ACTA1 ACTR3 TJP1	3.60e-06	8	141	3	11018051
Pubmed	PINK1 Content in Mitochondria is Regulated by ER-Associated Degradation.	FLNC SHROOM3 CAD DDX17 ACACA MYO1C SPTBN1 TLN1 EIF4B PLEC CTPS1	4.28e-06	477	141	11	31300519
Pubmed	LukS-PV inhibits hepatocellular carcinoma cells migration by downregulating HDAC6 expression.	CAD DDX17 MYO1C SPTBN1 ACTC1 ACTR3 TJP1 EIF4B TIMM50 DOCK7 PLEC QARS1	4.68e-06	580	141	12	35676659
Pubmed	Cell dynamics in fetal intestinal epithelium: implications for intestinal growth and morphogenesis.	SHROOM3 TUBG2 TUBG1 TJP1	4.91e-06	28	141	4	21880782
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	CAD DDX17 ACACA MYO1C SPTBN1 NIPSNAP1 EIF6 ACTR3 RBM22 TLN1 NEMF TIMM50 DOCK7 RBM15B MTREX CTPS1 QARS1 SPEN MAP4K4	5.26e-06	1425	141	19	30948266
Pubmed	Inhibition of calpain 1 restores plasma membrane stability to pharmacologically rescued Phe508del-CFTR variant.	FLNC SHROOM3 ACACA SPTBN1 TRIOBP ACTR3 TJP1 TLN1 PLEC CTPS1 QARS1	5.31e-06	488	141	11	31324722
Pubmed	TRIP6 functions in brain ciliogenesis.	TUBG2 TUBG1 TJP1	5.38e-06	9	141	3	34620853
Pubmed	Adult Neural Stem Cells and Multiciliated Ependymal Cells Share a Common Lineage Regulated by the Geminin Family Members.	TUBG2 TUBG1 TJP1	5.38e-06	9	141	3	30824354
Pubmed	mTORC2 interactome and localization determine aggressiveness of high-grade glioma cells through association with gelsolin.	FLNC CAD MYO1C SPTBN1 EIF6 ACTR3 TLN1 TIMM50 PLEC	5.57e-06	312	141	9	37120454
Pubmed	Myotubularin-related proteins 3 and 4 interact with polo-like kinase 1 and centrosomal protein of 55 kDa to ensure proper abscission.	ERCC4 ACTA1 MADD SBF1 NEMF TIMM50 DBR1	5.71e-06	167	141	7	25659891
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	CAD MYO1C SPTBN1 ACTA1 TRIOBP RNF213 ACTR3 MADD CEP350 SBF1 FAM171A2 TJP1 PDP1 TIMM50 LRP6 SETD7	5.95e-06	1049	141	16	27880917
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	FRAS1 VPS8 VIRMA MADD WDR47 TLN1 DOCK7 KATNIP SPEN VPS13B	6.83e-06	407	141	10	12693553
Pubmed	Cenpj Regulates Cilia Disassembly and Neurogenesis in the Developing Mouse Cortex.	TUBG2 TUBG1 NEK2 TJP1	9.67e-06	33	141	4	30626697
Pubmed	Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization.	CAD RAPGEF6 EDC3 DDX17 SPTBN1 DOCK7 CTPS1 ANKS1A	1.02e-05	255	141	8	15324660
Pubmed	HMMR acts in the PLK1-dependent spindle positioning pathway and supports neural development.	TUBG2 TUBG1 TJP1	1.05e-05	11	141	3	28994651
Pubmed	Defects in neural stem cell proliferation and olfaction in Chd7 deficient mice indicate a mechanism for hyposmia in human CHARGE syndrome.	TUBG2 TUBG1 TH	1.05e-05	11	141	3	19279158
Pubmed	Faciogenital Dysplasia 5 supports cancer stem cell traits in basal-like breast cancer by enhancing EGFR stability.	FLNC MYO1C ACTA1 ACTC1 TJP1 DOCK7 PLEC	1.37e-05	191	141	7	33762435
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	FRAS1 RAPGEF6 ERCC4 MADD PARP4 SBF1 NEMF DOCK7 DBR1 MTREX DHX34 MAP4K4	1.46e-05	650	141	12	38777146
Pubmed	Essential role of Ret for defining non-peptidergic nociceptor phenotypes and functions in the adult mouse.	RET TH	1.63e-05	2	141	2	21395865
Pubmed	Dissecting molecular differences between Wnt coreceptors LRP5 and LRP6.	LRP6 LRP5	1.63e-05	2	141	2	21887268
Pubmed	PAR1&2 driven placenta EVT invasion act via LRP5/6 as coreceptors.	LRP6 LRP5	1.63e-05	2	141	2	33136328
Pubmed	Investigation of changes in skeletal muscle alpha-actin expression in normal and pathological human and mouse hearts.	ACTA1 ACTC1	1.63e-05	2	141	2	20706863
Pubmed	LDL receptor-related proteins 5 and 6 in Wnt/beta-catenin signaling: arrows point the way.	LRP6 LRP5	1.63e-05	2	141	2	15084453
Pubmed	Co-deletion of Lrp5 and Lrp6 in the skeleton severely diminishes bone gain from sclerostin antibody administration.	LRP6 LRP5	1.63e-05	2	141	2	33164872
Pubmed	A dual role for talin in NK cell cytotoxicity: activation of LFA-1-mediated cell adhesion and polarization of NK cells.	ITGAL TLN1	1.63e-05	2	141	2	19124737
Pubmed	A 5' duplication of the alpha-cardiac actin gene in BALB/c mice is associated with abnormal levels of alpha-cardiac and alpha-skeletal actin mRNAs in adult cardiac tissue.	ACTA1 ACTC1	1.63e-05	2	141	2	3023046
Pubmed	MTOC reorientation occurs during FcgammaR-mediated phagocytosis in macrophages.	TUBG2 TUBG1	1.63e-05	2	141	2	17442887
Pubmed	LRP5/6 directly bind to Frizzled and prevent Frizzled-regulated tumour metastasis.	LRP6 LRP5	1.63e-05	2	141	2	25902418
Pubmed	Overexpression of γ-tubulin in non-small cell lung cancer.	TUBG2 TUBG1	1.63e-05	2	141	2	22806905
Pubmed	Transcripts of alpha-cardiac and alpha-skeletal actins are early markers for myogenesis in the mouse embryo.	ACTA1 ACTC1	1.63e-05	2	141	2	3075543
Pubmed	The involvement of the canonical Wnt-signaling receptor LRP5 and LRP6 gene variants with ADHD and sexual dimorphism: Association study and meta-analysis.	LRP6 LRP5	1.63e-05	2	141	2	30474181
Pubmed	In Adult Skeletal Muscles, the Co-Receptors of Canonical Wnt Signaling, Lrp5 and Lrp6, Determine the Distribution and Size of Fiber Types, and Structure and Function of Neuromuscular Junctions.	LRP6 LRP5	1.63e-05	2	141	2	36552732
Pubmed	Idiopathic Juvenile Osteoporosis: Clinical Experience from a Single Centre and Screening of LRP5 and LRP6 Genes.	LRP6 LRP5	1.63e-05	2	141	2	25783012
Pubmed	A talin-dependent LFA-1 focal zone is formed by rapidly migrating T lymphocytes.	ITGAL TLN1	1.63e-05	2	141	2	15983060
Pubmed	Gene targeting approaches in mice: assessing the roles of LRP5 and LRP6 in osteoblasts.	LRP6 LRP5	1.63e-05	2	141	2	19147944
Pubmed	Functional genomic analysis reveals the utility of the I/LWEQ module as a predictor of protein:actin interaction.	ACTA1 TLN1	1.63e-05	2	141	2	10581178
Pubmed	Decreased BMD and limb deformities in mice carrying mutations in both Lrp5 and Lrp6.	LRP6 LRP5	1.63e-05	2	141	2	15537447
Pubmed	LRP5 and LRP6 are not required for protective antigen-mediated internalization or lethality of anthrax lethal toxin.	LRP6 LRP5	1.63e-05	2	141	2	17335347
Pubmed	The Wnt co-receptor Lrp6 is required for normal mouse mammary gland development.	LRP6 LRP5	1.63e-05	2	141	2	19503830
Pubmed	Allocation of gamma-tubulin between oocyte cortex and meiotic spindle influences asymmetric cytokinesis in the mouse oocyte.	TUBG2 TUBG1	1.63e-05	2	141	2	17287496
Pubmed	Purification, crystallization and preliminary X-ray analysis of the plectin actin-binding domain.	ACTC1 PLEC	1.63e-05	2	141	2	12136158
Pubmed	LRP5-/6 gene polymorphisms and its association with risk of abnormal bone mass in postmenopausal women.	LRP6 LRP5	1.63e-05	2	141	2	37202775
Pubmed	Wnt receptors, bone mass, and fractures: gene-wide association analysis of LRP5 and LRP6 polymorphisms with replication.	LRP6 LRP5	1.63e-05	2	141	2	20926594
Pubmed	Common genetic variation of the low-density lipoprotein receptor-related protein 5 and 6 genes determines fracture risk in elderly white men.	LRP6 LRP5	1.63e-05	2	141	2	16355283
Pubmed	Transcriptional repressor DREAM regulates T-lymphocyte proliferation and cytokine gene expression.	KCNIP3 KCNIP2	1.63e-05	2	141	2	16177826
Pubmed	Ret deficiency in mice impairs the development of A5 and A6 neurons and the functional maturation of the respiratory rhythm.	RET TH	1.63e-05	2	141	2	16307583
Pubmed	Haemorrhagic snake venom metalloproteases and human ADAMs cleave LRP5/6, which disrupts cell-cell adhesions in vitro and induces haemorrhage in vivo.	LRP6 LRP5	1.63e-05	2	141	2	28425175
Pubmed	Evidence against a human cell-specific role for LRP6 in anthrax toxin entry.	LRP6 LRP5	1.63e-05	2	141	2	18350154
Pubmed	Murine tyrosine hydroxylase maps to the distal end of chromosome 7 within a region conserved in mouse and man.	ITGAL TH	1.63e-05	2	141	2	2889817
Interaction	SFN interactions	AMPD2 SHROOM3 RAPGEF6 EDC3 DOCK11 SPTBN1 ACTA1 VIRMA DENND4C MAP3K5 CEP350 FAM171A2 TJP1 EIF4B DOCK7 PLEC MTREX MAP4K4 ANKS1A	2.95e-07	692	139	19	int:SFN
Interaction	YWHAH interactions	AMPD2 SHROOM3 RAPGEF6 EDC3 DOCK11 SPTBN1 RFX7 VIRMA TUBG1 DENND4C MADD MAP3K5 CEP350 SBF1 FAM171A2 TJP1 EIF4B DOCK7 RBM15B PLEC MTREX DOCK6 MAP4K4 ANKS1A	5.02e-07	1102	139	24	int:YWHAH
Interaction	YWHAQ interactions	AMPD2 SHROOM3 CAD RAPGEF6 EDC3 ACACA DOCK11 RFX7 VIRMA DENND4C MAP3K5 CEP350 TH SBF1 FAM171A2 TJP1 TLN1 EIF4B DOCK7 FGG PLEC MTREX CTPS1 ANKS1A	6.50e-07	1118	139	24	int:YWHAQ
Interaction	TOP3B interactions	FLNC TEAD2 FRAS1 SHROOM3 CAD RAPGEF6 ACACA MYO1C POLG NIPSNAP1 EIF6 ACTR3 ELAC2 TUBG1 MADD MAP3K5 CELSR3 SBF1 TLN1 NPRL3 LRP5 PLEC SLC45A1 QARS1 DOCK6 ALKBH6 SPEN DHX34	7.37e-07	1470	139	28	int:TOP3B
Interaction	YWHAG interactions	AMPD2 SHROOM3 CAD RAPGEF6 EDC3 DDX17 DOCK11 SPTBN1 ACTC1 RFX7 VIRMA DENND4C MAP3K5 CEP350 SBF1 FAM171A2 TJP1 EIF4B TIMM50 DOCK7 RBM15B MTREX CTPS1 MAP4K4 ANKS1A	1.30e-06	1248	139	25	int:YWHAG
Interaction	NMS interactions	FRAS1 ADGRV1 WDR47 LRP6 LRP5	1.80e-06	30	139	5	int:NMS
Interaction	BAP1 interactions	FLNC CAD DDX17 ACACA ADAMTS1 SPTBN1 NIPSNAP1 CAST ACTC1 IDI1 MORC4 EIF6 ACTR3 TUBG1 AKAP12 UBE2L3 TLN1 EIF4B NEMF PANK4 DOCK7 PLEC BCAR3 CTPS1 QARS1	3.28e-06	1314	139	25	int:BAP1
Interaction	YWHAB interactions	AMPD2 SHROOM3 RAPGEF6 EDC3 DOCK11 SPTBN1 ACTC1 RFX7 VIRMA EIF6 ACTR3 DENND4C MAP3K5 CEP350 TH FAM171A2 TJP1 EIF4B DOCK7 MTREX ANKS1A	6.21e-06	1014	139	21	int:YWHAB
Interaction	MOB3C interactions	CAD ACACA DOCK11 PEG10 ACTA1 TLN1 DOCK7 MTREX CTPS1 QARS1 DOCK6 MAP4K4	8.57e-06	364	139	12	int:MOB3C
Interaction	RNF150 interactions	VIRMA MAP3K5 UBE2D4 UBE2L3	9.64e-06	20	139	4	int:RNF150
Interaction	YWHAZ interactions	AMPD2 SHROOM3 CAD RAPGEF6 EDC3 DOCK11 SPTBN1 ACTA1 ACTC1 VIRMA TUBG1 DENND4C MADD MAP3K5 TH SBF1 FAM171A2 TJP1 EIF4B DOCK7 KATNIP PLEC MTREX ANKS1A	1.13e-05	1319	139	24	int:YWHAZ
Interaction	LRRC31 interactions	CAD DDX17 ACACA MYO1C PARP4 SBF1 DOCK7 PLEC DOCK6	1.28e-05	205	139	9	int:LRRC31
Interaction	EFTUD2 interactions	AMPD2 CAD DDX17 ACACA SPTBN1 ACTA1 NIPSNAP1 CAST MRPL28 VIRMA EIF6 ELAC2 TUBG1 RBM22 UBE2L3 TJP1 MORF4L1 TLN1 EIF4B NEMF TIMM50 PLEC MTREX CTPS1 QARS1	1.78e-05	1449	139	25	int:EFTUD2
Interaction	KCTD13 interactions	FLNC CAD DDX17 MYO1C SPTBN1 ACTA1 NIPSNAP1 USP25 TPGS1 DGKZ GRM5 VIRMA ACTR3 MADD WDR47 ERMN SBF1 TJP1 TLN1 EIF4B DOCK7 SRPX FGG PLEC	2.79e-05	1394	139	24	int:KCTD13
Interaction	GSK3B interactions	CAD RAPGEF6 EDC3 ACACA MYO1C CAST TRIOBP TPGS1 DENND4C CEP350 TJP1 DOCK7 LRP6 PLEC CTPS1 QARS1 DHX34 ANKS1A	3.00e-05	868	139	18	int:GSK3B
Interaction	TRIM37 interactions	ERCC4 EDC3 MYO1C SPTBN1 ACTA1 ACTC1 VIRMA ACTR3 CEP350 TJP1 TIMM50 DOCK7 FGG PLEC SPEN	3.07e-05	630	139	15	int:TRIM37
Interaction	KCNA3 interactions	CHL1 CAD EDC3 DDX17 MYO1C SPTBN1 RNF213 DENND4C AKAP12 TLN1 EIF4B DOCK7 LRP6 CTPS1 QARS1 SPEN MAP4K4 ANKS1A	3.14e-05	871	139	18	int:KCNA3
Interaction	CDK7 interactions	ERCC4 DDX17 MYO1C SPTBN1 ACTA1 NIPSNAP1 ACTC1 HSP90AA5P EIF6 CCNA2 EIF4B PWWP3A SPEN	4.47e-05	501	139	13	int:CDK7
Interaction	OBSL1 interactions	PRUNE2 FLNC SHROOM3 CAD DDX17 ACTA1 NIPSNAP1 ACTC1 EIF6 ACTR3 TJP1 TLN1 NEMF TIMM50 PLEC MTREX SPEN MAP4K4	4.94e-05	902	139	18	int:OBSL1
Interaction	CDH2 interactions	SPTBN1 ACTA1 RET VIRMA CCNA2 LRP6 LRP5	5.11e-05	139	139	7	int:CDH2
Interaction	MYH9 interactions	SHROOM3 CAD ACACA MYO1C SPTBN1 ACTA1 USP25 TRIOBP ACTC1 VIRMA ACTR3 NEK2 TLN1 EIF4B DOCK7 PLEC	6.54e-05	754	139	16	int:MYH9
Interaction	HIF1AN interactions	CAD EDC3 MORC4 CEP350 TIMM50 DOCK7 MTREX SPEN MAP4K4 ANKS1A	7.16e-05	317	139	10	int:HIF1AN
Interaction	PINK1 interactions	FLNC SHROOM3 CAD DDX17 ACACA MYO1C SPTBN1 HSP90AA5P TLN1 EIF4B TIMM50 FGG PLEC CTPS1 ALOX15B	7.17e-05	679	139	15	int:PINK1
Interaction	CUL7 interactions	CAD DDX17 ACTA1 NIPSNAP1 EIF6 ACTR3 ERMN NSMF TJP1 TLN1 TIMM50 RBM15B PLEC MTREX QARS1 DOCK6 SPEN	7.37e-05	845	139	17	int:CUL7
Interaction	NXPH2 interactions	FRAS1 ADGRV1 MADD LRP5	7.59e-05	33	139	4	int:NXPH2
Interaction	CYFIP2 interactions	SPTBN1 TRIOBP ACTC1 DGKZ MRPL28 VIRMA MAP3K5 TIMM50 PLEC CTPS1	8.36e-05	323	139	10	int:CYFIP2
Interaction	PPP1CB interactions	CAD MYO1C SPTBN1 ACTA1 TRIOBP RNF213 ACTR3 NEK2 TJP1 EIF4B PLEC CTPS1	1.01e-04	469	139	12	int:PPP1CB
Interaction	EFL1 interactions	VIRMA EIF6 TLN1 PANK4 MTREX	1.15e-04	69	139	5	int:EFL1
Interaction	DYRK1A interactions	FLNC MYO1C ADAMTS1 SPTBN1 TRIOBP RFX7 VIRMA MAP3K5 CCNA2 WDR47 EIF4B DOCK7 DOCK6	1.19e-04	552	139	13	int:DYRK1A
Interaction	CDKL2 interactions	MYO1C SPTBN1 HSP90AA5P TJP1 PLEC	1.31e-04	71	139	5	int:CDKL2
Interaction	PRSS37 interactions	ADGRV1 LRP6 LRP5	1.37e-04	15	139	3	int:PRSS37
Interaction	DENND1C interactions	DENND4C MADD EIF4B	1.37e-04	15	139	3	int:DENND1C
Interaction	CCDC27 interactions	MADD ALOXE3 PLEC	1.37e-04	15	139	3	int:CCDC27
Interaction	CTTNBP2NL interactions	FLNC NIPSNAP1 VIRMA SBF1 MAP4K4	1.40e-04	72	139	5	int:CTTNBP2NL
Interaction	CRACD interactions	ACACA ACTC1 VIRMA ACTR3	1.63e-04	40	139	4	int:CRACD
Interaction	MECOM interactions	FLNC DDX17 MYO1C ACTA1 VIRMA TJP1 TIMM50 PLEC MTREX CTPS1	1.94e-04	358	139	10	int:MECOM
Interaction	SIRT7 interactions	FLNC CAD ACACA MYO1C SPTBN1 VIRMA EIF6 ACTR3 SBF1 TJP1 TLN1 DOCK7 PLEC MTREX SPEN	1.96e-04	744	139	15	int:SIRT7
Interaction	CAPZA2 interactions	MYO1C SPTBN1 ACTA1 TRIOBP ACTC1 VIRMA ACTR3 NEK2 EIF4B DOCK7 PLEC	1.99e-04	430	139	11	int:CAPZA2
Interaction	PRKCE interactions	CAD ACTA1 ACTC1 GRM5 VIRMA AKAP12 MAP4K4	2.01e-04	173	139	7	int:PRKCE
Interaction	SHC1 interactions	CAD ACACA MYO1C SPTBN1 ACTA1 RET AKAP12 SHC2 TIMM50 ANKS1A	2.12e-04	362	139	10	int:SHC1
Interaction	NAV2 interactions	SPTBN1 VIRMA MORF4L1 RBM15B	2.17e-04	43	139	4	int:NAV2
Interaction	PTGES3 interactions	CAD ERCC4 ACTC1 DGKZ HSP90AA5P VIRMA SBF1 FIG4 PWWP3A DHX34 MAP4K4	2.28e-04	437	139	11	int:PTGES3
Interaction	PODN interactions	FRAS1 LRP6 LRP5	2.43e-04	18	139	3	int:PODN
Interaction	MYO18A interactions	MYO1C SPTBN1 ACTA1 TRIOBP VIRMA ACTR3 FIG4 PLEC BCAR3	2.59e-04	303	139	9	int:MYO18A
Interaction	STYXL1 interactions	MYO1C SPTBN1 ACTA1 IDI1	2.59e-04	45	139	4	int:STYXL1
Interaction	HOOK1 interactions	ACACA IFT46 VIRMA RIMBP3 RBM22 TJP1 ALOXE3 PLEC	2.66e-04	240	139	8	int:HOOK1
Interaction	CMA1 interactions	FRAS1 ADGRV1 LRP6 MMP1	2.82e-04	46	139	4	int:CMA1
Interaction	NRAP interactions	FLNC ACTA1 TLN1	2.87e-04	19	139	3	int:NRAP
Interaction	UBA1 interactions	ACACA TUBG2 ACTC1 VIRMA UBE2D4 UBE2L3 TLN1 DOCK7 CTPS1 QARS1	3.12e-04	380	139	10	int:UBA1
Cytoband	4q28	SETD7 FGG	3.32e-04	9	141	2	4q28
Cytoband	22q11.21	RIMBP3 UBE2L3 RIMBP3C RIMBP3B	3.96e-04	111	141	4	22q11.21
GeneFamily	Guanylate cyclase receptors\|DENN/MADD domain containing	DENND4C MADD SBF1	3.26e-04	25	98	3	504
GeneFamily	Actins	ACTA1 ACTC1	4.30e-04	6	98	2	929
GeneFamily	Arachidonate lipoxygenases	ALOXE3 ALOX15B	4.30e-04	6	98	2	407
GeneFamily	Glutamate metabotropic receptors\|Protein phosphatase 1 regulatory subunits	GRM5 GRM6	7.97e-04	8	98	2	281
GeneFamily	Ubiquitin conjugating enzymes E2	UBE2D4 UBE2L3 UBE2L5	1.42e-03	41	98	3	102
GeneFamily	Low density lipoprotein receptors	LRP6 LRP5	2.18e-03	13	98	2	634
GeneFamily	Potassium voltage-gated channel regulatory subunits\|DASH family	KCNIP3 KCNIP2	2.92e-03	15	98	2	858
Coexpression	PARENT_MTOR_SIGNALING_UP	MYO1C TUBG2 POLG NIPSNAP1 CAST TRIOBP IFT46 MADD MAP3K5 CEP350 UBE2L3 PANK4 KATNIP SRPX DOCK6	3.67e-07	567	139	15	M16909
Coexpression	CARRILLOREIXACH_MRS3_VS_LOWER_RISK_HEPATOBLASTOMA_UP	ACACA NIPSNAP1 EIF6 LRP5 SLC29A4	6.82e-06	50	139	5	M45038
Coexpression	MITSIADES_RESPONSE_TO_APLIDIN_DN	CAD SPTBN1 CCNA2 NEK2 EIF4B PWWP3A PLEC CTPS1 SPEN	7.89e-06	250	139	9	M11318
Coexpression	GSE21670_UNTREATED_VS_TGFB_IL6_TREATED_STAT3_KO_CD4_TCELL_DN	SPTBN1 CAST DGKZ ITGAL INO80D ACTR3 PARP4 ALKBH6	1.20e-05	200	139	8	M7444
Coexpression	DEBIASI_APOPTOSIS_BY_REOVIRUS_INFECTION_DN	FLNC CAD POLG PARP4 SBF1 SUOX FIG4 LRP5 PLEC	1.74e-05	276	139	9	M3063
ToppCell	facs-Marrow-T-cells-3m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	USP25 ITGAL GRM6 ARSB FGG MAP4K4 ALOX15B	1.82e-06	181	141	7	7286700396676fdc41d9723979b8b408177aceb9
ToppCell	PND01-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_prolif\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DOCK11 DGKZ ITGAL CCNA2 ARSB NSMF DHX34	1.89e-06	182	141	7	57f8b8d7b132f3ad6f2b1e79c3812fe938657d2c
ToppCell	facs-Thymus-nan-3m-Lymphocytic-DN4_thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RAPGEF6 ACTA1 DGKZ ITGAL RBM15B FGG MAP4K4	2.11e-06	185	141	7	a2cae8c657e4f4d121476798e424876f7e247973
ToppCell	facs-Thymus-nan-3m-Lymphocytic-DN4_thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RAPGEF6 ACTA1 DGKZ ITGAL RBM15B FGG MAP4K4	2.11e-06	185	141	7	d50406a9a5b8d75110ba5985741aa2293950c543
ToppCell	droplet-Fat-SCAT-30m-Endothelial-Cd36+\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TCF15 SPTBN1 ACTA1 PALMD TJP1 CD36 DOCK6	2.34e-06	188	141	7	e901a9bdf00b8e91806f445af66647373bf62661
ToppCell	droplet-Fat-SCAT-30m-Endothelial-endothelial_cell\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TCF15 SPTBN1 ACTA1 PALMD TJP1 CD36 DOCK6	2.34e-06	188	141	7	5cf060bb8adaefa9964187195d67993c1248ef47
ToppCell	droplet-Fat-SCAT-30m-Endothelial\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TCF15 SPTBN1 ACTA1 PALMD TJP1 CD36 DOCK6	2.34e-06	188	141	7	449f9602df3c83b2110eb479a00d428d1b55b423
ToppCell	COVID-19-Heart-Mito_EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	FLNC TCF15 ACTA1 ACTC1 CASQ1 PALMD CD36	2.51e-06	190	141	7	ea74e0e38bcaba125b48c88331e9ba09228d3178
ToppCell	facs-BAT-Fat-3m-Endothelial-nan\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TCF15 ADAMTS1 SPTBN1 PALMD AKAP12 TJP1 CD36	2.79e-06	193	141	7	e340064cd146deac03f2d0fd43e2e218bb6057c9
ToppCell	facs-BAT-Fat-3m-Endothelial-endothelial_cell\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TCF15 ADAMTS1 SPTBN1 PALMD AKAP12 TJP1 CD36	2.79e-06	193	141	7	a211b386fd0fb9da9937361d29d90925a72c9715
ToppCell	facs-BAT-Fat-3m-Endothelial\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TCF15 ADAMTS1 SPTBN1 PALMD AKAP12 TJP1 CD36	2.79e-06	193	141	7	3086c33f4d6fab66966818737f95ae4d6b2615b0
ToppCell	facs-Heart\|facs / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TCF15 SPTBN1 ACTC1 AKAP12 CD36 SRPX ADAMTSL2	3.19e-06	197	141	7	6a9571c0a3238b39214afdece93d7541bc8a0a70
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	SPTBN1 RNF213 DGKZ PALMD TJP1 CD36 DOCK6	3.53e-06	200	141	7	dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCell	390C-Endothelial_cells-Endothelial-B_(Artery)-\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	MYO1C ADAMTS1 PALMD ADAMTS6 KCNJ2 TLN1 SRPX	3.53e-06	200	141	7	c32ad15dede3f879007c0b856f2fed1f5b058103
ToppCell	Control_saline-Endothelial-Endothelial\|Control_saline / Treatment groups by lineage, cell group, cell type	SPTBN1 PALMD TJP1 PLEC DOCK6 MAP4K4 ADAMTSL2	3.53e-06	200	141	7	e77eba6172cabf85b8028638ed35299f2f079cd8
ToppCell	Control_saline-Endothelial\|Control_saline / Treatment groups by lineage, cell group, cell type	SPTBN1 PALMD TJP1 PLEC DOCK6 MAP4K4 ADAMTSL2	3.53e-06	200	141	7	3372c488a39fe812fa94e4f0564594186fea3db5
ToppCell	390C-Endothelial_cells-Endothelial-B_(Artery)\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	MYO1C ADAMTS1 PALMD ADAMTS6 KCNJ2 TLN1 SRPX	3.53e-06	200	141	7	8a2c6c53a39fab86750526083f7254b7413b29af
ToppCell	facs-Marrow-Granulocytes-3m-Myeloid-basophil\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AMPD2 GRM6 SUOX TJP1 KCNJ2 ALOX15B	2.02e-05	175	141	6	1b35acece23712ab7e3f92d9d68266efd38b3ef5
ToppCell	facs-Marrow-Granulocytes-3m-Myeloid-basophil\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AMPD2 GRM6 SUOX TJP1 KCNJ2 ALOX15B	2.02e-05	175	141	6	a9f88054e2c28d604c65ed785f63021aadb7f4c8
ToppCell	facs-Large_Intestine-Proximal-3m-Epithelial-enteroendocrine_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRUNE2 RET KCNIP3 SHC2 CELSR3 SLC29A4	2.22e-05	178	141	6	30ca37f70d267cc9b40ca3e211f16d30360c3e6b
ToppCell	ILEUM-non-inflamed-(7)_Lymphatics\|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	SPTBN1 RET AKAP12 TJP1 SRPX ANKS1A	2.29e-05	179	141	6	99777a8931356d1206b8ab22aaa1b1d5a600b809
ToppCell	PND07-Epithelial-Epithelial_Airway-Neurosecretory-PNEC\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PRUNE2 RET KCNIP3 KCNIP2 TH SLC45A1	2.67e-05	184	141	6	3e5c68a99c10eb1ddc1048bea4aa9f6b8e2746ff
ToppCell	PND07-Epithelial-Epithelial_Airway-Neurosecretory-PNEC-PNEC_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PRUNE2 RET KCNIP3 KCNIP2 TH SLC45A1	2.67e-05	184	141	6	1e2f0cec50475a1cf2973a5082826bbc60fc9a68
ToppCell	droplet-Fat-Mat-18m-Endothelial-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TCF15 SPTBN1 ACTC1 PALMD CD36 LRP5	2.76e-05	185	141	6	d9be5853acdda7b1ac819cf50c7940d1d2362d15
ToppCell	COVID-19-lung-Artery_EC\|lung / Disease (COVID-19 only), tissue and cell type	CHL1 PALMD ADAMTS6 TJP1 SRPX DOCK6	3.02e-05	188	141	6	eecd7482b3c97d7f49993cb17edfab30c61232fc
ToppCell	droplet-Fat-Scat-21m-Endothelial-Cd36+\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TCF15 SPTBN1 PALMD TJP1 CD36 DOCK6	3.02e-05	188	141	6	8671fdbc4138e6f9559920779c98628ed80f0da3
ToppCell	Adult-Endothelial-capillary_endothelial_cell_(Cap1)-D122\|Adult / Lineage, Cell type, age group and donor	SPTBN1 PALMD AKAP12 ADAMTS6 BCAR3 DOCK6	3.02e-05	188	141	6	02a62888e9db29d20133eeca1686d302545a39c9
ToppCell	droplet-Mammary_Gland-nan-21m-Endothelial-endothelial_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TCF15 SPTBN1 PALMD AKAP12 CD36 DOCK6	3.11e-05	189	141	6	8ced0381ea042ba47680a02b617a2368fa2c54c8
ToppCell	droplet-Mammary_Gland-nan-21m-Endothelial\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TCF15 SPTBN1 PALMD AKAP12 CD36 DOCK6	3.11e-05	189	141	6	403a82bb416aed13b9d31411ad17bdc4ce2a95fb
ToppCell	droplet-Fat-Scat-21m-Endothelial-endothelial_cell\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TCF15 SPTBN1 PALMD TJP1 CD36 DOCK6	3.20e-05	190	141	6	d3e46cf800a07ca9b01c78192962d223b9785d05
ToppCell	droplet-Fat-Scat-21m-Endothelial\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TCF15 SPTBN1 PALMD TJP1 CD36 DOCK6	3.20e-05	190	141	6	dd89ef1ecea20b2f6fbdc6cea4ca41b28b3ed822
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 DOCK11 GRM5 AKAP12 PARP4 FAM171A2	3.49e-05	193	141	6	ffa1932da2979d7b63dbac32eb5788346a3f5b2a
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CHL1 DOCK11 GRM5 AKAP12 PARP4 FAM171A2	3.49e-05	193	141	6	0f2167eef8203a5659c8c72e4e77646003d64797
ToppCell	COVID-19-Endothelial_cells-Inflamed_endothelial_cells\|COVID-19 / group, cell type (main and fine annotations)	SPTBN1 PALMD AKAP12 MMP1 BCAR3 DOCK6	3.49e-05	193	141	6	979ebefa527f86bebeea5d94e626ee6c1cc7d53b
ToppCell	COVID-19-kidney-FLT1+PLVAP+EC\|kidney / Disease (COVID-19 only), tissue and cell type	SPTBN1 PALMD AKAP12 SHC2 DOCK6 ACSL5	3.49e-05	193	141	6	479abb1cd2eb978b8a4fdb900069a6329fc8cade
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 DOCK11 GRM5 AKAP12 PARP4 FAM171A2	3.60e-05	194	141	6	8ddcaaf24cee6e30d5be52c0cbf778cfba309c53
ToppCell	droplet-Lung-21m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_endothelial_cell\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ADAMTS1 SPTBN1 PALMD AKAP12 TJP1 CD36	3.70e-05	195	141	6	27d1f228103ff5d8941aa8a8d15726cd09298a30
ToppCell	Epithelial-Epithelial-A_(AT1)\|Epithelial / shred on cell class and cell subclass (v4)	FRAS1 MYO1C SPTBN1 TJP1 TLN1 CREB3L2	3.81e-05	196	141	6	41b21a18125cc95bc8adde3369e4abd029cf137d
ToppCell	Parenchymal-10x5prime-Endothelial-Endothelia_vascular-VE_systemic_arterial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	ADAMTS1 PALMD SHC2 ADAMTS6 KCNJ2 SRPX	3.92e-05	197	141	6	ad4a3b5da2190be9495382a2952991e1de9f190d
ToppCell	390C-Fibroblasts-Fibroblast-K_(Pericytes)\|390C / Donor, Lineage, Cell class and subclass (all cells)	PRUNE2 FLNC MYO1C ADAMTS1 ACTA1 ACTC1	4.03e-05	198	141	6	c82a151f9f1477d4a401457173b8d72af776c137
ToppCell	390C-Fibroblasts-Fibroblast-K_(Pericytes)-\|390C / Donor, Lineage, Cell class and subclass (all cells)	PRUNE2 FLNC MYO1C ADAMTS1 ACTA1 ACTC1	4.03e-05	198	141	6	dc63b56bb6291e527b172d603569376286262845
ToppCell	COVID-19-lung-Capillary_2\|lung / Disease (COVID-19 only), tissue and cell type	SPTBN1 PALMD INO80D AKAP12 ADAMTS6 DOCK6	4.14e-05	199	141	6	793ce71b78a68033ef4419ed571e1dd86b40124f
ToppCell	390C-Fibroblasts-Fibroblast-K_(Pericytes)-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	PRUNE2 FLNC MYO1C ADAMTS1 ACTA1 ACTC1	4.26e-05	200	141	6	2bc7f462a551292de2501028164573935232f899
ToppCell	Parenchymal-10x5prime-Endothelial-Endothelia_vascular\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	SPTBN1 PALMD AKAP12 TJP1 SRPX DOCK6	4.26e-05	200	141	6	2989325b0e78ab42f362cfb59e34a4fce7f8e869
ToppCell	Parenchymal-10x5prime-Endothelial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	SPTBN1 PALMD AKAP12 TJP1 SRPX DOCK6	4.26e-05	200	141	6	0e648e9eb96c83a94505d07323785a7a40997eb0
ToppCell	LPS_only-Endothelial-Endothelial-Gen_Cap\|LPS_only / Treatment groups by lineage, cell group, cell type	DDX17 SPTBN1 PALMD TJP1 CD36 DOCK6	4.26e-05	200	141	6	eb94a5111ef0e903ee5be9f7efe571b4e6d5fce1
ToppCell	Control_saline-Endothelial-Endothelial-Gen_Cap\|Control_saline / Treatment groups by lineage, cell group, cell type	SPTBN1 PALMD TJP1 CD36 DOCK6 MAP4K4	4.26e-05	200	141	6	3b97920e1e6e2f09ddba2a861baa9c00c2970f4c
ToppCell	Bronchial-10x5prime-Endothelial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	TEAD2 SPTBN1 PALMD AKAP12 TJP1 DOCK6	4.26e-05	200	141	6	ad34c978cc6b89b4c1c8c9b2fb2a938051b555a0
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-5w-Mesenchymal-Mesoderm\|5w / Sample Type, Dataset, Time_group, and Cell type.	USP25 VIRMA SHC2 FAM171A2 DBR1 SLC29A4	4.26e-05	200	141	6	0927061536a664b4f7feb9e5b0a8c11ca0d5955c
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-6m-Mesenchymal-Mesoderm\|6m / Sample Type, Dataset, Time_group, and Cell type.	FLNC ACTA1 ACTC1 CD36 C1orf105 SETD7	4.26e-05	200	141	6	0f6851baf0cf2a8b0c95a7a585c4407c330c5f6c
ToppCell	Control_saline-Endothelial-Endothelial-Activated_Alv_Cap\|Control_saline / Treatment groups by lineage, cell group, cell type	SPTBN1 RNF213 TH TJP1 PLEC ADAMTSL2	4.26e-05	200	141	6	be55cef682ba87250dad97689332c8820b3a7420
ToppCell	(01)_IL1RL1+\|World / shred by cell type by condition	ADAMTS1 AKAP12 PLEC BCAR3 MAP4K4 ALOX15B	4.26e-05	200	141	6	501420901bf3ec1b050e0d14596a9f9f3fdfc928
ToppCell	H1299\|World / Cell line, Condition and Strain	FLNC MYO1C PEG10 AKAP12 EIF4B TIMM50	4.26e-05	200	141	6	23f08d7cffacfced48785cd3ad230ecadb95713f
ToppCell	390C-Fibroblasts-Fibroblast-K_(Pericytes)\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	PRUNE2 FLNC MYO1C ADAMTS1 ACTA1 ACTC1	4.26e-05	200	141	6	8b80a65b69b36ed405214564b939452c90aa40d6
ToppCell	frontal_cortex-Neuronal-glutamatergic_neuron-L2/3_IT-L2/3_IT_ALM_Sla\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	EPYC PALMD KCNJ2 BHLHE22 ADAMTSL2	6.33e-05	132	141	5	ddebc0b233fdbb73ceb70187945bbed8fd273f2a
ToppCell	LPS_only-Endothelial-Endothelial-FOXM1\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PALMD CCNA2 NEK2 FAM171A2 DBR1	6.79e-05	134	141	5	4d8f7ddad02fe76a614771e115ebb8e04623ba85
ToppCell	frontal_cortex-Neuronal-glutamatergic_neuron-L2/3_IT\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	EPYC PALMD KCNJ2 BHLHE22 ADAMTSL2	1.09e-04	148	141	5	d5cace5605bff2bb8248fadb51f2dad7539930ba
ToppCell	LPS-antiTNF-Endothelial-Epi-like-Gen_Cap\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ACACA ZNF684 ALOXE3 SETD7 ADAMTSL2	1.16e-04	150	141	5	9cb3332924bd67c966873343c14445e30d3f384f
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 DOCK11 GRM5 PARP4 ARSB	1.27e-04	153	141	5	d6526d17826470534b766df144c74e73eb83fdad
ToppCell	PND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TCF15 POLG RET CCNA2 CTPS1	1.35e-04	155	141	5	8e239470799426ea474a36f57e1b7e0d9365ca5f
ToppCell	PND01-03-samps-Endothelial-Postnatal_endothelial-endothelial_cells_C\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	ADAMTS1 PALMD MORC4 TIMM50 SLC29A4	1.39e-04	156	141	5	6c8f442ed94ae31e6832b68137e98ae78091ac6c
ToppCell	PND03-Immune-Immune_Myeloid-DC-cDC1-cDC1_prolif\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CASQ1 RFX7 GCSAM ARSB ALOX15B	1.39e-04	156	141	5	af47a4b17342bdb3cb62d7e2d52a81168e588629
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Neuronal-neuron_precursor\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CHL1 ADGRV1 RET KCNIP2 SLC29A4	1.71e-04	163	141	5	99cf60dc87f7ce288553091bffcd85109a02bd8f
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Neuronal-neuron_precursor-Neuroblast\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CHL1 ADGRV1 RET KCNIP2 SLC29A4	1.71e-04	163	141	5	510c0af66e82c5a8cf8edd0547dae4018a87dbbf
ToppCell	droplet-Thymus-nan-24m-Lymphocytic-Macrophage\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRUNE2 RET KCNJ2 DOCK7 DOCK6	2.02e-04	169	141	5	780fb0050852626062a729dd1b82b0cf61e7e9ca
ToppCell	3'-GW_trimst-2-SmallIntestine-Neuronal-Glial_immature-ENCC/glia_Progenitor\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CHL1 ADGRV1 RFX7 RBM15B BCAR3	2.13e-04	171	141	5	b51bbeacb172e8b5de519ada85543d7ae9914b3c
ToppCell	5'-GW_trimst-2-LymphNode-Endothelial-blood_vessel_EC-venous_capillary\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SPTBN1 PALMD TJP1 CD36 DOCK6	2.13e-04	171	141	5	b3e6e31dfe3623b960ccf692fdbd236fa4039923
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_artery-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ADAMTS1 PALMD TJP1 SRPX DOCK6	2.13e-04	171	141	5	1597459c971d6befa991d59dc66b41b6a522f797
ToppCell	COVID-19-kidney-PEC\|kidney / Disease (COVID-19 only), tissue and cell type	PRUNE2 DOCK11 GRM5 AKAP12 MAP3K5	2.19e-04	172	141	5	36a96714a0eb6ac438648135336c9791881ddadb
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NUGGC RET DENND4C AKAP12 KCNJ2	2.37e-04	175	141	5	1b4cefae400bf756d09ece32d3f5c0bd4c6ad73f
ToppCell	343B-Lymphocytic-NK_cells-NK_cell_E\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	NUGGC ACACA TUBG2 GCSAM CTPS1	2.37e-04	175	141	5	78a86cac3e6c0d115c997d1c29ee0e24af54551f
ToppCell	facs-Brain_Myeloid-Cerebellum-3m-Myeloid-microglial_cell\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTS1 ARSB KCNJ2 FGG MAP4K4	2.37e-04	175	141	5	1ea6cf9da26601646f57fa14d558a5e9e1f0b345
ToppCell	PND07-Epithelial-Epithelial_Airway-Neurosecretory\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RET KCNIP3 KCNIP2 TH SLC45A1	2.37e-04	175	141	5	19eda8b5d39dc93d79737ebdbeeba5ec0cb23c51
ToppCell	facs-Heart-RV-18m-Endothelial-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TCF15 SPTBN1 PALMD TJP1 CD36	2.43e-04	176	141	5	fb3d03f64592e1df1d9785d9f2e70938d7ff9ce8
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell_prolif\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PALMD SHC2 ADAMTS6 CD36 PLEC	2.43e-04	176	141	5	1df7b6ce2519ad99bacbbaf1a8d5929e11513faa
ToppCell	facs-Heart-RV-18m-Endothelial-endothelial_cell_of_coronary_artery\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TCF15 SPTBN1 PALMD TJP1 CD36	2.43e-04	176	141	5	99410c121f55adbc7fcc013c8fa8905a45dba76b
ToppCell	PBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ADAMTS1 RNF213 ITGAL VIRMA MTREX	2.50e-04	177	141	5	d3e6c768b88b7906f3c7fdd00ba20842212c14b1
ToppCell	PBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ADAMTS1 RNF213 ITGAL VIRMA MTREX	2.50e-04	177	141	5	f8f101c772c043636bedd6b2ec81409b1d2599bf
ToppCell	COVID-19_Mild-Lymphoid_T/NK-NK_activated\|COVID-19_Mild / Disease group, lineage and cell class	ADAMTS1 RNF213 ITGAL VIRMA MTREX	2.50e-04	177	141	5	6978a22fef40c8b455342373abe7593f5ede0fa4
ToppCell	PBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	ADAMTS1 RNF213 ITGAL VIRMA MTREX	2.50e-04	177	141	5	936ab2b180a052387124f68d0c7f41c0b164e748
ToppCell	PBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	ADAMTS1 RNF213 ITGAL VIRMA MTREX	2.50e-04	177	141	5	d5aeda113afaa2425874394610344570c9078478
ToppCell	droplet-Liver-LIVER_HEP-30m-Lymphocytic-B_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACTA1 GRM6 EFHC2 C1orf105 SLC29A4	2.57e-04	178	141	5	d3cbdec9d75f076e565baca05ede292cca7758a4
ToppCell	367C-Endothelial_cells-Endothelial-B_(Artery)\|367C / Donor, Lineage, Cell class and subclass (all cells)	CHL1 ADAMTS1 PALMD TJP1 SRPX	2.57e-04	178	141	5	e1e96a0e3ff718ebf676a982bc63e8ced6984059
ToppCell	5'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-Mature_venous_EC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TCF15 NUP210L PALMD CCNA2 NEK2	2.57e-04	178	141	5	ea10117026021c959ffc871fc377cdb3e161d264
ToppCell	367C-Endothelial_cells-Endothelial-B_(Artery)-\|367C / Donor, Lineage, Cell class and subclass (all cells)	CHL1 ADAMTS1 PALMD TJP1 SRPX	2.57e-04	178	141	5	363e8b23b3834692a8a79e5fdc7b43bd3a4dab5e
ToppCell	droplet-Liver-LIVER_HEP-30m-Lymphocytic-B_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACTA1 CASQ1 GRM6 C1orf105 SLC29A4	2.63e-04	179	141	5	4135f9e8cd8494cbc189e5210dded84659643fb8
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c01-FCGR3A\|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)	ACACA DGKZ ADGRV1 FBXO8 KCNJ2	2.70e-04	180	141	5	12f3c4c4aa7fe03c0ef847bd4d4942c808015f5f
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_ILC-NK_cell\|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)	ACACA DGKZ ADGRV1 FBXO8 KCNJ2	2.70e-04	180	141	5	1bc01bb76d0d3f8db74f9244436d3e6d6015ed5d
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRUNE2 ITGAL GCSAM CD36 ZBTB18	2.70e-04	180	141	5	6ac62bf1251978c8c12e715f7b73144fca619794
ToppCell	Control-Epithelial_cells-AT2\|Control / group, cell type (main and fine annotations)	SHROOM3 ACACA ADGRV1 CD36 ALOX15B	2.70e-04	180	141	5	198b19e7910b4a8cc7e820c525ab357c7f99f578
ToppCell	facs-Marrow-B-cells-18m-Hematologic-MPP_Fraction_B_+_C\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ELAC2 SBF1 ADAMTS6 FIG4 PDP1	2.70e-04	180	141	5	7368ab31c3273374ef260f0d710d4eea83cbc4a2
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_ILC\|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)	ACACA DGKZ ADGRV1 FBXO8 KCNJ2	2.70e-04	180	141	5	2a28fbfe10a340c8662c2c8be33792f41fc09088
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CHL1 PRUNE2 FRAS1 DOCK11 ADGRV1	2.77e-04	181	141	5	9d782ba5cf5a172cb4f447763fc50e5b13ef7dd9
ToppCell	PBMC-Convalescent-Lymphocyte-B-B_cell-B_naive-B_naive-2\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	PEG10 UBE2D4 FIG4 PDP1 CERS4	2.77e-04	181	141	5	75035a3211e524bb659b82e6979f7d3a3121ae70
ToppCell	COVID-19-Heart-CM_+_EC_+_Pericyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	FLNC ACTA1 ACTC1 PALMD CD36	2.77e-04	181	141	5	719eb532453ab7cd7893726885bc75d74a10b21e
ToppCell	E18.5-samps-Endothelial-Mature_fetal_endothelial-endothelial_cells_A\|E18.5-samps / Age Group, Lineage, Cell class and subclass	TCF15 RNF213 PALMD CCNA2 TJP1	2.84e-04	182	141	5	ea4f6c8f600ffe9f8e0609637b3371a5ac48ca03
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CHL1 PRUNE2 FRAS1 DOCK11 ADGRV1	2.84e-04	182	141	5	eb138aa1dca9373f1586600f258df06dcf56d81f
ToppCell	TCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Ductal_Carcinoma-5\|TCGA-Breast / Sample_Type by Project: Shred V9	EPYC IDI1 MORC4 ACTR3 MMP1	2.84e-04	182	141	5	9e48d5b634603bc7a8d29290202a311457678328
ToppCell	wk_15-18-Mesenchymal-Myofibro_&_SMC-Early_airway_SMC_2\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	PRUNE2 ADAMTS1 ACTC1 CASQ1 ADAMTSL2	2.91e-04	183	141	5	a1d4f25e13f5b9e92a9ca0a804a7bed5df8fb2fe
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CHL1 PRUNE2 DOCK11 GRM5 PARP4	2.91e-04	183	141	5	738e94b50c4c08c727d4eed0708dda08aa6891b4
Drug	Chrysene-1,4-quinone [100900-16-1]; Down 200; 15.4uM; HL60; HG-U133A	CAD ACACA MYO1C SPTBN1 ITGAL MAP3K5 CCNA2 CTPS1 ACSL5	2.80e-06	193	138	9	1773_DN
Drug	CAY10397; Down 200; 10uM; PC3; HT_HG-U133A	DDX17 TRIOBP MRPL28 SBF1 PDP1 PWWP3A PLEC SPEN DHX34	3.18e-06	196	138	9	7087_DN
Drug	genistein; Down 200; 10uM; HL60; HT_HG-U133A	ADAMTS1 MOSPD3 RET INO80D NSMF CD36 NPRL3 LRP5 DHX34	3.46e-06	198	138	9	6194_DN
Drug	Lynestrenol [52-76-6]; Down 200; 14uM; MCF7; HT_HG-U133A	EDC3 SPTBN1 AKAP12 UBE2D4 NPRL3 PWWP3A DOCK6 DHX34 ANKS1A	3.75e-06	200	138	9	5355_DN
Drug	NSC618487	PEG10 ACTA1 CAST ACTC1 DGKZ ITGAL GRM5 GRM6 MADD MAP3K5 CCNA2 TH NEK2 TJP1 KCNJ2 ALOXE3 MMP1 ALOX15B	1.42e-05	933	138	18	CID000005279
Drug	5-fluorocytidine	POLG UCK1 PLEC CTPS1	1.48e-05	25	138	4	CID000016861
Drug	PHA-00846566E [724718-26-7]; Down 200; 10uM; PC3; HT_HG-U133A	TUBG2 POLG MAP3K5 CEP350 TH SBF1 FIG4 DHX34	2.22e-05	191	138	8	7086_DN
Drug	econazole	TCF15 FRMD7 ALOXE3 QARS1 ALOX15B	2.47e-05	57	138	5	CID000003198
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; HL60; HG-U133A	CAD ACACA MYO1C ITGAL INO80D MAP3K5 TLN1 MTREX	2.57e-05	195	138	8	1561_DN
Drug	BAS 012416453; Down 200; 38uM; MCF7; HT_HG-U133A	DDX17 TUBG2 MOSPD3 TH UBE2L3 PDP1 NPRL3 LRP6	2.87e-05	198	138	8	6908_DN
Drug	S 30	MORF4L1 EIF4B LRP5 QARS1	3.13e-05	30	138	4	CID000213100
Drug	NSC 523214	MYO1C SPTBN1 ACTA1 ACTC1 TUBG1 TJP1 NPRL3	3.24e-05	147	138	7	CID000004752
Drug	AC1L1KMJ	SPTBN1 ACTA1 CAST ACTC1 ACTR3 TUBG1 AKAP12 TJP1 CD36 MMP1 PLEC VPS13B	3.42e-05	476	138	12	CID000030956
Drug	1-benzyl-apdc	GRM5 GRM6	3.65e-05	2	138	2	CID005310978
Drug	dofetilide	PEG10 ACTC1 KCNIP2 KCNJ2 QARS1	4.03e-05	63	138	5	CID000071329
Disease	complex cortical dysplasia with other brain malformations 4 (implicated_via_orthology)	TUBG2 TUBG1	2.02e-05	2	133	2	DOID:0090138 (implicated_via_orthology)
Disease	brain ischemia (biomarker_via_orthology)	ADAMTS1 RET AKAP12 TH TJP1	1.01e-04	102	133	5	DOID:2316 (biomarker_via_orthology)
Disease	erythrocyte count, mean corpuscular hemoglobin concentration, mean corpuscular volume, hematocrit, obsolete_red blood cell distribution width, mean corpuscular hemoglobin	MRPL28 NPRL3 LRP5	1.91e-04	25	133	3	EFO_0004305, EFO_0004348, EFO_0004526, EFO_0004527, EFO_0004528, EFO_0005192
Disease	migraine disorder, type 1 diabetes mellitus	SLC9B1 SLC45A1	2.00e-04	5	133	2	MONDO_0005147, MONDO_0005277
Disease	myocardial infarction (implicated_via_orthology)	MAP3K5 KCNJ2 CD36 MMP1	2.29e-04	66	133	4	DOID:5844 (implicated_via_orthology)
Disease	clubfoot (implicated_via_orthology)	FRAS1 RET	2.99e-04	6	133	2	DOID:11836 (implicated_via_orthology)
Disease	tendinitis (biomarker_via_orthology)	LRP5 MMP1	2.99e-04	6	133	2	DOID:971 (biomarker_via_orthology)
Disease	atrial fibrillation (is_marker_for)	KCNJ2 CD36 MMP1	4.04e-04	32	133	3	DOID:0060224 (is_marker_for)
Disease	pemphigus (is_implicated_in)	CAST CD36	4.17e-04	7	133	2	DOID:9182 (is_implicated_in)
Disease	hair colour measurement	CHL1 FRAS1 SHROOM3 ADAMTS1 ADGRV1 GRM5 AKAP12 LRP5 SLC45A1 BCAR3	4.90e-04	615	133	10	EFO_0007822
Disease	Moyamoya disease (implicated_via_orthology)	ACTA1 ACTC1	5.55e-04	8	133	2	DOID:13099 (implicated_via_orthology)
Disease	Unilateral agenesis of kidney	FRAS1 RET	5.55e-04	8	133	2	C0266294
Disease	autosomal dominant nonsyndromic deafness 20 (implicated_via_orthology)	ACTA1 ACTC1	5.55e-04	8	133	2	DOID:0110550 (implicated_via_orthology)
Disease	Baraitser-Winter syndrome 1 (implicated_via_orthology)	ACTA1 ACTC1	5.55e-04	8	133	2	DOID:0081112 (implicated_via_orthology)
Disease	thoracic aortic aneurysm (implicated_via_orthology)	ACTA1 ACTC1	5.55e-04	8	133	2	DOID:14004 (implicated_via_orthology)
Disease	sleep latency	FRAS1 ERCC4 TCF15	6.22e-04	37	133	3	EFO_0005280
Disease	intestinal atresia (implicated_via_orthology)	ACTA1 ACTC1	8.86e-04	10	133	2	DOID:10486 (implicated_via_orthology)
Disease	patent ductus arteriosus (implicated_via_orthology)	ACTA1 ACTC1	8.86e-04	10	133	2	DOID:13832 (implicated_via_orthology)
Disease	Shortened QT interval	KCNJ2 LRP5	1.08e-03	11	133	2	C0151879
Disease	pulmonary fibrosis (implicated_via_orthology)	CD36 MMP1	1.29e-03	12	133	2	DOID:3770 (implicated_via_orthology)
Disease	gallbladder carcinoma (is_marker_for)	ACTR3 TJP1	1.29e-03	12	133	2	DOID:4948 (is_marker_for)
Disease	Cardiomyopathy, Dilated	ACTA1 ACTC1 CD36	1.34e-03	48	133	3	C0007193
Disease	cancer (implicated_via_orthology)	ERCC4 DDX17 RET IDI1 NEK2 TIMM50	1.39e-03	268	133	6	DOID:162 (implicated_via_orthology)
Disease	level of Phosphatidylinositol (18:1_18:1) in blood serum	DOCK7 DOCK6	1.52e-03	13	133	2	OBA_2045159
Disease	Charcot-Marie-Tooth disease type 4	SBF1 FIG4	1.52e-03	13	133	2	cv:C4082197
Disease	tyrosine-protein kinase receptor Tie-1, soluble measurement	NPRL3 ADAMTSL2	1.52e-03	13	133	2	EFO_0008312
Disease	Cleft palate, cleft lip	SHROOM3 CAST VIRMA PDP1 EIF4B VPS13B	1.71e-03	279	133	6	EFO_0003959, HP_0000175
Disease	autosomal dominant polycystic kidney disease (implicated_via_orthology)	FLNC LRP5	1.77e-03	14	133	2	DOID:898 (implicated_via_orthology)
Disease	Tubular Aggregate Myopathy	ACTA1 CASQ1	1.77e-03	14	133	2	C0410207
Disease	hippocampal atrophy	PRUNE2 ARSB VPS13B	2.08e-03	56	133	3	EFO_0005039
Disease	Pheochromocytoma, Extra-Adrenal	RET TH	2.32e-03	16	133	2	C1257877
Disease	Van Buchem disease	LRP5 ADAMTSL2	2.62e-03	17	133	2	C0432272
Disease	level of Phosphatidylinositol (18:0_18:1) in blood serum	DOCK7 DOCK6	2.94e-03	18	133	2	OBA_2045155
Disease	Pheochromocytoma	RET TH	3.28e-03	19	133	2	C0031511
Disease	mean reticulocyte volume	CAD NUP210L TPGS1 MOSPD3 CEP350 CD36 C1orf105 NPRL3 DBR1 CERS4	3.41e-03	799	133	10	EFO_0010701
Disease	level of Phosphatidylinositol (18:0_18:2) in blood serum	DOCK7 DOCK6	4.00e-03	21	133	2	OBA_2045156
Disease	pulse pressure measurement	SHROOM3 MYO1C TRIOBP RNF213 DENND4C MADD CCNA2 FAM171A2 UBE2L3 MORF4L1 NPRL3 MMP1 DHX34 CREB3L2	4.14e-03	1392	133	14	EFO_0005763

Protein segments in the cluster

Peptide	Gene	Start	Entry
SHTVLDFYEPRRPED	ALKBH6	131	Q3KRA9
EDRDGRVYPHPQDLL	CERS4	26	Q9HA82
TFYNELRVAPEEHPT	ACTA1	91	P68133
RSPLAEHRPDAYQDV	BCAR3	31	O75815
PAESAHEPRLSAEYE	AKAP12	361	Q02952
HEPRLSAEYEKVELP	AKAP12	366	Q02952
ALDELRAVIPYAHSP	BHLHE22	261	Q8NFJ8
VHLLPDEVPEIEEDY	ADGRV1	4716	Q8WXG9
HTSLYDEDKVPRDEP	ACACA	1271	Q13085
TDPRHARSPEDEYEL	GCSAM	136	Q8N6F7
AAREEDEHPYELLLT	ANKS1A	446	Q92625
REPDEHCSEVELPYP	AMPD2	336	Q01433
AFHYKRPTDEPESLE	ADAMTS6	786	Q9UKP5
DLVRDRTPPHLLYSD	RBM15B	526	Q8NDT2
YRHEKPTDPDDPLAD	RBM22	181	Q9NW64
PHVVYLDDREHALTP	RIMBP3B	1021	A6NNM3
PHVVYLDDREHALTP	RIMBP3C	1021	A6NJZ7
PPSDRDAEHYDTAIL	ADAMTS1	341	Q9UHI8
PITIVHEIDEDSPLY	KCNJ2	266	P63252
FERPQYAEILADHPD	MORF4L1	276	Q9UBU8
DEEDVRYNIVHSLPP	PALMD	391	Q9NP74
PKAHYEPADRAREVE	MAP4K4	556	O95819
APPIVVTLADYDHVE	FRAS1	3161	Q86XX4
YDVAEAEEHFPAPAR	GRM5	1001	P41594
TPELLRRYPLEDHTE	MADD	31	Q8WXG6
TPRDFPSHYEEALRD	MAGEB1	296	P43366
DYHRPSVEEILENPL	NEK2	256	P51955
EDYPDTAPVIHGVDV	CHL1	806	O00533
ERYPLDHARAAEPLL	NEMF	151	O60524
PTVPYHTILFTEDRD	KATNIP	1546	O60303
GTYPDEHFTEEAPRR	ALOXE3	656	Q9BYJ1
IRAEERTSPHSYVEP	FRMD7	511	Q6ZUT3
DIRHAIAIDYDPLEG	LRP5	371	O75197
REVVEHVEPLRPYES	EFHC2	201	Q5JST6
TTVYCDDHELDAIPP	EPYC	126	Q99645
SGHPALERRPEYLEE	HSP90AA5P	16	Q58FG0
HYAASSLIPPEAIER	NPRL3	236	Q12980
DEDIRDSPFIAHILP	FLNC	646	Q14315
TYPALREEAPREHVE	KCNIP2	216	Q9NS61
IHAPEERGEYLETLI	FBXO8	221	Q9NRD0
LPRAVIRHPDYDEEG	POLG	821	P54098
TPVDEHVYPDHRLVD	PEG10	516	Q86TG7
LEDIRHAIAIDYDPV	LRP6	356	O75581
DSYCDALTRPEPVHE	ADAMTSL2	601	Q86TH1
RRDDPSIIPILYDHE	NSMF	366	Q6X4W1
PTRYRHDENILESEP	EDC3	241	Q96F86
PSDHTELEEYRPEFS	PARP4	576	Q9UKK3
EELTDVDSPLPHYRV	ERMN	31	Q8TAM6
TAEPEVTYHRLRPQD	PDP1	396	Q9P0J1
PYRPTDLFDELVAHE	SBF1	436	O95248
TEREHEPPYEISVQE	PANK4	71	Q9NVE7
PERPATLILYEDLVH	FAM171A2	126	A8MVW0
NDYVALVHPDLDRET	EIF6	111	P56537
AKQVRPEHPAETEYD	FGG	431	P02679
LRAEPEDHYFLLTEP	ACTR3	101	P61158
PADYEHLPVSAEIKE	IFT46	66	Q9NQC8
EEVPPEEINYLTRIH	IDI1	121	Q13907
PHSVIDYEEQRTVDP	GRM6	721	O15303
IPHVTIRYAEIPDES	DOCK11	1006	Q5JSL3
EILEFPAREVYAPHT	DOCK6	531	Q96HP0
DPVDLEDYLITHPLA	DOCK7	56	Q96N67
PNDSVRVTHPDEARY	FIG4	136	Q92562
NPNEEEHRTYLDIEP	CD36	361	P16671
VLALLYHEPPEDDKA	CASQ1	66	P31415
DPPVISKRRHYDTDE	CEP350	581	Q5VT06
DSRYFDLHDPPQDVV	DENND4C	471	Q5VZ89
LKCVEHAYEPTPDDV	ACSL5	286	Q9ULC5
DDTIPPEYRHLLDDN	CAST	611	P20810
PEERHDLSREYPHIV	ARSB	481	P15848
ARVPLHYLETELEDP	INO80D	136	Q53TQ3
ILEIEHDPSAPDYLE	DBR1	266	Q9UK59
VEHPEVARLTPYEVD	DDX17	136	Q92841
YLLDHAPPEILDAVE	DGKZ	841	Q13574
DEKPVSVNEVPDYHE	CCNA2	166	P20248
IIGRIPAYDPDVSDH	CELSR3	1191	Q9NYQ7
VSEEHLRRYAPDPVL	CHIC1	76	Q5VXU3
HTYPILREDAPAEHV	KCNIP3	201	Q9Y2W7
LESIDHKYPPEERGD	DHX34	366	Q14147
VIYEIPPSDAADEEH	SLC45A1	761	Q9Y2W3
SRNLLIYEEHSPPEE	CREB3L2	426	Q70SY1
ADYIPVAVEHAIEPD	NUP210L	1471	Q5VU65
HSNDDDVYRAPPIDR	EIF4B	56	P23588
IPERDSRYSQPLHEE	MAP3K5	711	Q99683
GTYPDEHFTEEAPRR	ALOX15B	621	O15296
TEAVLPKLHLDEDYP	NIPSNAP1	91	Q9BPW8
DEEDEEPPRVLLYHE	PWWP3A	391	Q2TAK8
LEYVRSHPLDPIDTV	QARS1	91	P47897
EPHPVEDDLYKERTR	NUGGC	11	Q68CJ6
YRHTHLDDPIAEVEP	RAPGEF6	1391	Q8TEU7
AVLHIREDPESVYLP	PRUNE2	2456	Q8WUY3
YTPDLPRADVDHAIE	MMP1	121	P03956
PHVVYLDDREHALTP	RIMBP3	1021	Q9UFD9
VLPHLELREIGYDSE	MORC4	906	Q8TE76
DLEPITSQEEPVRYH	CTPS1	341	P17812
EETVIDVPEPYNHVS	SETD7	271	Q8WTS6
ESVLRDSPPPHEDYE	SHROOM3	1491	Q8TF72
IVLHAEEPYIENEEP	SPESP1	131	Q6UW49
FVEPPDAVDSYQRHL	TEAD2	236	Q15562
RLHSAEASPEEEIYP	VPS8	761	Q8N3P4
VPCHYEDLERLPDAA	ITGAL	996	P20701
DSPLEDDEVGYSHPR	SRPX	36	P78539
APPGETRHNLEREEY	TRIOBP	1256	Q9H2D6
EEIANYRPTLDTLHE	SPTBN1	791	Q01082
TFYNELRVAPEEHPT	ACTC1	91	P68032
DDIPTESIHYRLPIL	C1orf105	131	O95561
YAETTLEHARPEEPS	C12orf4	106	Q9NQ89
ILPESPGSHEESREY	RNF213	1566	Q63HN8
AHVLYPDVRLLSEDE	TCF15	11	Q12870
ECHSIYEESPERDTP	WDR47	366	O94967
RVCAYPDVIDPSAHE	WDR47	631	O94967
SDYPLVDEPGKHRES	ZNF684	81	Q5T5D7
TVLEHYALEDDPLAA	TIMM50	296	Q3ZCQ8
EVPTYDFVTHSRLPE	UCK1	111	Q9HA47
IELAVRPHSAPEYED	ELAC2	161	Q9BQ52
PEEEVHYHLPVARAT	SPEN	3156	Q96T58
THEVALPAEEDYLPL	MTREX	111	P42285
ADARGPPDHEEHLYV	SHC2	401	P98077
DDEHYIPRAVLLDLE	TUBG1	56	P23258
QPEHPLRADLAEEYS	UBE2L5	116	A0A1B0GUS4
EAAYHPEVAPDVRLR	TLN1	2221	Q9Y490
RVQYEPAHLAPLRED	ZBTB18	306	Q99592
PIPSHYDVQDRFRIE	MOSPD3	101	O75425
KEEEDPTTTLDHRPY	ZNF646	451	O15015
LAQEDTPPETDYRLH	USP25	791	Q9UHP3
LHPEDPERRAAIYDK	MRPL28	176	Q13084
EHPETSLPKQEVYDE	RFX7	21	Q2KHR2
ALETARVSAPHLEPY	SLC9B1	451	Q4ZJI4
DPEESHRLPVEVAYK	PLEC	4191	Q15149
HLPPQEDTYVEVDLE	CAD	1741	P27708
LYVHALRDAPEEVPS	RET	51	P07949
PPEDIVRSNHYDPEE	TJP1	1336	Q07157
YLLAEEPHVEPAGER	UBL4B	136	Q8N7F7
DHLEPPYEIEARDFL	ZNF445	181	P59923
PEEVALLEEYIPTRH	VPS13B	626	Q7Z7G8
TTLDEPVPDDRYHAI	SLC29A4	56	Q7RTT9
DDEHYIPRAVLLDLE	TUBG2	56	Q9NRH3
ETSDPYADDPVRHPA	SUOX	171	P51687
SDPYALTRVLHEVEP	ERCC4	561	Q92889
DDPLVPEIAHTYKAD	UBE2D4	116	Q9Y2X8
LEARPEEPIAFLAHY	TPGS1	56	Q6ZTW0
APHREDYFEPISPDR	VIRMA	211	Q69YN4
QPEHPLRADLAEEYS	UBE2L3	116	P68036
HGDPIPRVEYTAEEI	TH	246	P07101
EVPPHLFAVADTVYR	MYO1C	111	O00159