Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionparathyroid hormone receptor activity

PTH1R PTH2R

1.50e-062252GO:0004991
GeneOntologyMolecularFunctionpeptide receptor activity

SCTR OGFR PTH1R PTH2R

2.61e-05140254GO:0001653
GeneOntologyMolecularFunctionpeptide hormone binding

SCTR PTH1R PTH2R

4.36e-0555253GO:0017046
GeneOntologyMolecularFunctionMHC class I receptor activity

KIR3DL1 KIR3DS1

2.27e-0418252GO:0032393
GeneOntologyMolecularFunctionhormone binding

SCTR PTH1R PTH2R

2.82e-04103253GO:0042562
GeneOntologyMolecularFunctionamide binding

SCTR KIR3DL1 PTH1R PTH2R

4.86e-04299254GO:0033218
GeneOntologyMolecularFunctionG protein-coupled peptide receptor activity

SCTR PTH1R PTH2R

5.97e-04133253GO:0008528
DomainHormR

SCTR PTH1R PTH2R

4.78e-0625253SM00008
DomainHRM

SCTR PTH1R PTH2R

6.79e-0628253PF02793
DomainGPCR_2_secretin-like_CS

SCTR PTH1R PTH2R

1.23e-0534253IPR017983
DomainG_PROTEIN_RECEP_F2_1

SCTR PTH1R PTH2R

2.03e-0540253PS00649
DomainG_PROTEIN_RECEP_F2_3

SCTR PTH1R PTH2R

2.03e-0540253PS50227
DomainGPCR_2_extracellular_dom

SCTR PTH1R PTH2R

2.03e-0540253IPR001879
DomainG_PROTEIN_RECEP_F2_2

SCTR PTH1R PTH2R

3.98e-0550253PS00650
Domain7tm_2

SCTR PTH1R PTH2R

3.98e-0550253PF00002
DomainGPCR_2-like

SCTR PTH1R PTH2R

6.89e-0560253IPR017981
DomainGPCR_2_secretin-like

SCTR PTH1R PTH2R

6.89e-0560253IPR000832
DomainG_PROTEIN_RECEP_F2_4

SCTR PTH1R PTH2R

7.24e-0561253PS50261
DomainGalactose-bd-like

CUL7 NTN3

6.97e-0394252IPR008979
DomainKRAB

ZNF17 ZKSCAN7 ZNF780B

1.18e-02358253PS50805
DomainKRAB

ZNF17 ZKSCAN7 ZNF780B

1.18e-02358253PF01352
Domain-

RLF ZNF17 ZKSCAN7 ZNF780B

1.19e-026792543.30.160.60
DomainKRAB

ZNF17 ZKSCAN7 ZNF780B

1.27e-02369253SM00349
Domainzf-C2H2

RLF ZNF17 ZKSCAN7 ZNF780B

1.28e-02693254PF00096
DomainKRAB

ZNF17 ZKSCAN7 ZNF780B

1.28e-02370253IPR001909
DomainZnf_C2H2/integrase_DNA-bd

RLF ZNF17 ZKSCAN7 ZNF780B

1.28e-02694254IPR013087
DomainZINC_FINGER_C2H2_2

RLF ZNF17 ZKSCAN7 ZNF780B

1.86e-02775254PS50157
DomainZINC_FINGER_C2H2_1

RLF ZNF17 ZKSCAN7 ZNF780B

1.87e-02777254PS00028
DomainZnf_C2H2-like

RLF ZNF17 ZKSCAN7 ZNF780B

2.03e-02796254IPR015880
DomainZnf_C2H2

RLF ZNF17 ZKSCAN7 ZNF780B

2.11e-02805254IPR007087
PathwayWP_GPCRS_CLASS_B_SECRETINLIKE

SCTR PTH1R PTH2R

6.54e-0624223MM15992
PathwayWP_GPCRS_CLASS_B_SECRETINLIKE

SCTR PTH1R PTH2R

6.54e-0624223M39643
PathwayKEGG_MEDICUS_REFERENCE_BCR_PLCG_ITPR_SIGNALING_PATHWAY

BTK ITPR3

8.31e-059222M47852
PathwayREACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS

SCTR PTH1R PTH2R

1.07e-0460223MM14964
PathwayREACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS

SCTR PTH1R PTH2R

4.03e-0494223M797
Pubmed

Calmodulin interacts with the cytoplasmic tails of the parathyroid hormone 1 receptor and a sub-set of class b G-protein coupled receptors.

SCTR PTH1R PTH2R

3.92e-081025315670850
Pubmed

A method for killer-cell immunoglobulin-like receptor (KIR) 3DL1/3DS1 genotyping using DNA recovered from frozen plasma.

KIR3DL1 KIR3DS1

4.96e-07225223524032
Pubmed

Allele imputation for the killer cell immunoglobulin-like receptor KIR3DL1/S1.

KIR3DL1 KIR3DS1

4.96e-07225235192601
Pubmed

Development of a PCR-SSOP approach capable of defining the natural killer cell inhibitory receptor (KIR) gene sequence repertoires.

KIR3DL1 KIR3DS1

4.96e-07225211098931
Pubmed

Evaluation of KIR3DL1/KIR3DS1 allelic polymorphisms in Kenyan children with endemic Burkitt lymphoma.

KIR3DL1 KIR3DS1

4.96e-07225237647275
Pubmed

Allele diversity of the killer cell immunoglobulin-like receptors KIR3DL1/S1 and the combination with their HLA ligands in Mexican Mestizos from Mexico City.

KIR3DL1 KIR3DS1

4.96e-07225230365992
Pubmed

Association of the KIR3DS1*013 and KIR3DL1*004 alleles with susceptibility to ankylosing spondylitis.

KIR3DL1 KIR3DS1

4.96e-07225220131260
Pubmed

No association of KIR3DL1 or KIR3DS1 or their alleles with ankylosing spondylitis.

KIR3DL1 KIR3DS1

4.96e-07225219874556
Pubmed

Protective genotypes in HIV infection reflect superior function of KIR3DS1+ over KIR3DL1+ CD8+ T cells.

KIR3DL1 KIR3DS1

4.96e-07225225112829
Pubmed

Functional polymorphism of the KIR3DL1/S1 receptor on human NK cells.

KIR3DL1 KIR3DS1

4.96e-07225217182560
Pubmed

Unusual selection on the KIR3DL1/S1 natural killer cell receptor in Africans.

KIR3DL1 KIR3DS1

4.96e-07225217694054
Pubmed

Ligand-receptor interactions at the parathyroid hormone receptors: subtype binding selectivity is mediated via an interaction between residue 23 on the ligand and residue 41 on the receptor.

PTH1R PTH2R

4.96e-07225218539702
Pubmed

Evaluation of KIR3DL1/KIR3DS1 polymorphism in Behçet's disease.

KIR3DL1 KIR3DS1

4.96e-07225227708262
Pubmed

PTH-receptors regulate norepinephrine release in human heart and kidney.

PTH1R PTH2R

4.96e-07225221756942
Pubmed

Genetic control of variegated KIR gene expression: polymorphisms of the bi-directional KIR3DL1 promoter are associated with distinct frequencies of gene expression.

KIR3DL1 KIR3DS1

4.96e-07225219008943
Pubmed

Parathyroid hormone stimulates juxtaglomerular cell cAMP accumulation without stimulating renin release.

PTH1R PTH2R

4.96e-07225222896038
Pubmed

Meiotic recombination generates rich diversity in NK cell receptor genes, alleles, and haplotypes.

KIR3DL1 KIR3DS1

4.96e-07225219411600
Pubmed

Investigation of killer cell immunoglobulin-like receptor gene diversity in KIR3DL1 and KIR3DS1 in a transplant population.

KIR3DL1 KIR3DS1

4.96e-07225218331531
Pubmed

Contribution of KIR3DL1/3DS1 to ankylosing spondylitis in human leukocyte antigen-B27 Caucasian populations.

KIR3DL1 KIR3DS1

4.96e-07225216805919
Pubmed

Contribution of functional KIR3DL1 to ankylosing spondylitis.

KIR3DL1 KIR3DS1

4.96e-07225220818412
Pubmed

HLA class I subtype-dependent expansion of KIR3DS1+ and KIR3DL1+ NK cells during acute human immunodeficiency virus type 1 infection.

KIR3DL1 KIR3DS1

4.96e-07225219386717
Pubmed

Role of natural killer cells in a cohort of elite suppressors: low frequency of the protective KIR3DS1 allele and limited inhibition of human immunodeficiency virus type 1 replication in vitro.

KIR3DL1 KIR3DS1

4.96e-07225219211742
Pubmed

Putative role of KIR3DL1/3DS1 alleles and HLA-Bw4 ligands with end stage renal disease and long term renal allograft survival.

KIR3DL1 KIR3DS1

4.96e-07225228942035
Pubmed

The profile of KIR3DL1 and KIR3DS1 alleles in an African American population resembles that found in African populations.

KIR3DL1 KIR3DS1

4.96e-07225220230527
Pubmed

Multiple copies of KIR 3DL/S1 and KIR 2DL4 genes identified in a number of individuals.

KIR3DL1 KIR3DS1

1.49e-06325212826375
Pubmed

KIR3DL1/S1 genotypes and KIR2DS4 allelic variants in the AB KIR genotypes are associated with Plasmodium-positive individuals in malaria infection.

KIR3DL1 KIR3DS1

1.49e-06325219859704
Pubmed

KIR3DS1/L1 and HLA-Bw4-80I are associated with HIV disease progression among HIV typical progressors and long-term nonprogressors.

KIR3DL1 KIR3DS1

1.49e-06325224059286
Pubmed

Allelic expression patterns of KIR3DS1 and 3DL1 using the Z27 and DX9 antibodies.

KIR3DL1 KIR3DS1

1.49e-06325217301953
Pubmed

Analysis of killer immunoglobulin-like receptor genes in ankylosing spondylitis.

KIR3DL1 KIR3DS1

1.49e-06325219019897
Pubmed

Allelic polymorphism synergizes with variable gene content to individualize human KIR genotype.

KIR3DL1 KIR3DS1

1.49e-06325211859120
Pubmed

High-throughput genotyping of KIR2DL2/L3, KIR3DL1/S1, and their HLA class I ligands using real-time PCR.

KIR3DL1 KIR3DS1

2.97e-06425219522772
Pubmed

The silent KIR3DP1 gene (CD158c) is transcribed and might encode a secreted receptor in a minority of humans, in whom the KIR3DP1, KIR2DL4 and KIR3DL1/KIR3DS1 genes are duplicated.

KIR3DL1 KIR3DS1

2.97e-06425215580659
Pubmed

Expression profile of KIR3DS1/KIR3DL1 receptors in association with immunological responses in TB, HIV and HIV/TB infected patients.

KIR3DL1 KIR3DS1

2.97e-06425237169313
Pubmed

Activating KIR genes are associated with ankylosing spondylitis in Asian populations.

KIR3DL1 KIR3DS1

2.97e-06425218638658
Pubmed

Open conformers of HLA-F are high-affinity ligands of the activating NK-cell receptor KIR3DS1.

KIR3DL1 KIR3DS1

2.97e-06425227455421
Pubmed

Genetic variation in the PTH pathway and bone phenotypes in elderly women: evaluation of PTH, PTHLH, PTHR1 and PTHR2 genes.

PTH1R PTH2R

2.97e-06425218280230
Pubmed

Polymorphism and domain variability of human killer cell inhibitory receptors.

KIR3DL1 KIR3DS1

2.97e-0642529059894
Pubmed

Association of killer cell immunoglobulin-like receptor genotypes with microscopic polyangiitis.

KIR3DL1 KIR3DS1

4.95e-06525216508981
Pubmed

Killer cell immunoglobulin-like receptor genotypes in Japanese patients with type 1 diabetes.

KIR3DL1 KIR3DS1

4.95e-06525217990989
Pubmed

Killer cell immunoglobulin-like receptor gene polymorphism in lymphoproliferative diseases of granular lymphocytes in a Japanese population.

KIR3DL1 KIR3DS1

7.43e-06625220528243
Pubmed

Functionally and structurally distinct NK cell receptor repertoires in the peripheral blood of two human donors.

KIR3DL1 KIR3DS1

1.04e-0572529430220
Pubmed

HLA-F and MHC-I Open Conformers Bind Natural Killer Cell Ig-Like Receptor KIR3DS1.

KIR3DL1 KIR3DS1

1.39e-05825227649529
Pubmed

KIR haplotype content at the allele level in 77 Northern Irish families.

KIR3DL1 KIR3DS1

1.39e-05825217200871
Pubmed

Human diversity in killer cell inhibitory receptor genes.

KIR3DL1 KIR3DS1

1.39e-0582529430221
Pubmed

Selective inhibition of heterotrimeric Gs signaling. Targeting the receptor-G protein interface using a peptide minigene encoding the Galpha(s) carboxyl terminus.

SCTR PTH1R PTH2R

1.74e-057025312036966
Pubmed

Alternatively spliced forms of human killer inhibitory receptors.

KIR3DL1 KIR3DS1

1.78e-0592528662091
Pubmed

Combination of KIR and HLA gene variants augments the risk of developing birdshot chorioretinopathy in HLA-A*29-positive individuals.

KIR3DL1 KIR3DS1

1.78e-05925218340360
Pubmed

Different patterns of evolution in the centromeric and telomeric regions of group A and B haplotypes of the human killer cell Ig-like receptor locus.

KIR3DL1 KIR3DS1

2.22e-051025221206914
Pubmed

Natural killer cells and immune surveillance.

KIR3DL1 KIR3DS1

2.72e-051125218830515
Pubmed

[Genotype analysis of killer cell immunoglobulin-like receptors in Graves' disease patients].

KIR3DL1 KIR3DS1

2.72e-051125219664392
Pubmed

Association of killer cell immunoglobulin-like receptor 2DL5 with systemic lupus erythematosus and accompanying infections.

KIR3DL1 KIR3DS1

3.26e-051225220371502
Pubmed

[Relationship between CMV reactivation and KIR haplotype/HLA-Cw genotype in patients after unrelated-donor hematopoietic stem cell transplantation.].

KIR3DL1 KIR3DS1

3.26e-051225220137308
Pubmed

Distribution of killer cell immunoglobulin-like receptors (KIR) and their HLA-C ligands in two Iranian populations.

KIR3DL1 KIR3DS1

3.26e-051225219936734
Pubmed

Association of killer cell immunoglobulin-like receptors with primary Sjogren's syndrome.

KIR3DL1 KIR3DS1

3.26e-051225219181658
Pubmed

[Polymorphism of killer cell immunoglobulin-like receptor gene and its correlation with leukemia].

KIR3DL1 KIR3DS1

3.26e-051225217490516
Pubmed

[Study on the polymorphism of killer cell immunoglobulin like receptor (KIR) gene with systemic lupus erythematosus of North population in China].

KIR3DL1 KIR3DS1

3.85e-051325218687225
Pubmed

KIR and HLA genotypes are associated with disease progression and survival following autologous hematopoietic stem cell transplantation for high-risk neuroblastoma.

KIR3DL1 KIR3DS1

3.85e-051325219934297
Pubmed

Different KIRs confer susceptibility and protection to adults with latent autoimmune diabetes in Latvian and Asian Indian populations.

KIR3DL1 KIR3DS1

3.85e-051325219120281
Pubmed

Frequencies of killer immunoglobulin-like receptor genotypes influence susceptibility to spontaneous abortion.

KIR3DL1 KIR3DS1

4.49e-051425219875891
Pubmed

Multiple sclerosis associates with LILRA3 deletion in Spanish patients.

KIR3DL1 KIR3DS1

4.49e-051425219421224
Pubmed

Distribution of killer cell immunoglobulin-like receptor genes in the Chinese Han population.

KIR3DL1 KIR3DS1

4.49e-051425215896204
Pubmed

[Genotype and haplotype analysis of killer cell immunoglobulin-like receptors in ankylosing spondylitis].

KIR3DL1 KIR3DS1

4.49e-051425219489269
Pubmed

Donors with group B KIR haplotypes improve relapse-free survival after unrelated hematopoietic cell transplantation for acute myelogenous leukemia.

KIR3DL1 KIR3DS1

4.49e-051425218945962
Pubmed

Killer cell immunoglobulin-like receptor gene diversity in a Caucasian population of southern Brazil.

KIR3DL1 KIR3DS1

5.18e-051525220082646
Pubmed

Inhibitory KIR and specific HLA-C gene combinations confer susceptibility to or protection against chronic hepatitis B.

KIR3DL1 KIR3DS1

5.18e-051525220643584
Pubmed

Killer cell immunoglobulin-like receptor genotype and killer cell immunoglobulin-like receptor-human leukocyte antigen C ligand compatibility affect the severity of hepatitis C virus recurrence after liver transplantation.

KIR3DL1 KIR3DS1

5.18e-051525219326408
Pubmed

Disparate distribution of activating and inhibitory killer cell immunoglobulin-like receptor genes in patients with systemic lupus erythematosus.

KIR3DL1 KIR3DS1

5.18e-051525219926642
Pubmed

Killer cell immunoglobulin-like receptors in HLA-B27-associated acute anterior uveitis, with and without axial spondyloarthropathy.

KIR3DL1 KIR3DS1

5.18e-051525219850842
Pubmed

Natural killer-cell receptor polymorphisms and posttransplantation non-Hodgkin lymphoma.

KIR3DL1 KIR3DS1

5.18e-051525220207982
Pubmed

Killer immunoglobulin-like receptors (KIR2DL2 and/or KIR2DS2) in presence of their ligand (HLA-C1 group) protect against chronic myeloid leukaemia.

KIR3DL1 KIR3DS1

5.18e-051525219493232
Pubmed

[Killer cell immunoglobin-like receptor and its ligand gene polymorphisms in Hunan Han patients with type 1 diabetes].

KIR3DL1 KIR3DS1

5.18e-051525220356536
Pubmed

Killer cell immunoglobulin-like receptor gene-cluster 3DS1-2DL5-2DS1-2DS5 predisposes susceptibility to Vogt-Koyanagi-Harada syndrome in Japanese individuals.

KIR3DL1 KIR3DS1

5.92e-051625219897003
Pubmed

Influence of activating and inhibitory killer immunoglobulin-like receptors on predisposition to recurrent miscarriages.

KIR3DL1 KIR3DS1

5.92e-051625219279038
Pubmed

No association of KIR genes with Behcet's disease.

KIR3DL1 KIR3DS1

5.92e-051625217868255
Pubmed

A study of the killer cell immunoglobulin-like receptor gene KIR2DS1 in a Caucasoid Brazilian population with psoriasis vulgaris.

KIR3DL1 KIR3DS1

5.92e-051625218643961
Pubmed

Distribution of killer cell immunoglobulin-like receptor (KIR) genotypes in patients with familial Mediterranean fever.

KIR3DL1 KIR3DS1

5.92e-051625219309280
Pubmed

Diversity of killer cell immunoglobulin-like receptor genes in Indonesian populations of Java, Kalimantan, Timor and Irian Jaya.

KIR3DL1 KIR3DS1

5.92e-051625219000141
Pubmed

Diversity of killer cell immunoglobulin-like receptor genes in Indonesian populations of Sumatra, Sulawesi and Moluccas Islands.

KIR3DL1 KIR3DS1

5.92e-051625220670355
Pubmed

Activating killer cell immunoglobulin-like receptor genes' association with recurrent miscarriage.

KIR3DL1 KIR3DS1

5.92e-051625219527230
Pubmed

Report from the killer immunoglobulin-like receptor (KIR) anthropology component of the 15th International Histocompatibility Workshop: worldwide variation in the KIR loci and further evidence for the co-evolution of KIR and HLA.

KIR3DL1 KIR3DS1

5.92e-051625220331834
Pubmed

Polymorphisms of KIR gene and HLA-C alleles: possible association with susceptibility to HLA-B27-positive patients with ankylosing spondylitis.

KIR3DL1 KIR3DS1

5.92e-051625220652381
Pubmed

Asian population frequencies and haplotype distribution of killer cell immunoglobulin-like receptor (KIR) genes among Chinese, Malay, and Indian in Singapore.

KIR3DL1 KIR3DS1

5.92e-051625218668235
Pubmed

HLA-DQA1*0505 sharing and killer immunoglobulin-like receptors in sub fertile couples: report from the 15th International Histocompatibility Workshop.

KIR3DL1 KIR3DS1

5.92e-051625220210919
Pubmed

Natural killer cell receptor repertoire and their ligands, and the risk of CMV infection after kidney transplantation.

KIR3DL1 KIR3DS1

6.70e-051725219032228
Pubmed

The role of killer immunoglobulin-like receptor haplotypes on the outcome of unrelated donor haematopoietic SCT for thalassaemia.

KIR3DL1 KIR3DS1

6.70e-051725220173792
Pubmed

[Analysis of natural killer cell immunoglobulin-like receptor genes in Chinese].

KIR3DL1 KIR3DS1

6.70e-051725219218127
Pubmed

Role of killer cell immunoglobulin-like receptor gene content and human leukocyte antigen-C group in susceptibility to human T-lymphotropic virus 1-associated myelopathy/tropical spastic paraparesis in Peru.

KIR3DL1 KIR3DS1

6.70e-051725220483367
Pubmed

[Effects of killer immunoglobulin-like receptor and human leukocyte antigen class I ligand on the prognosis of related donor hematopoietic stem cell transplantation].

KIR3DL1 KIR3DS1

6.70e-051725219968064
Pubmed

KIR genes and KIR ligands affect occurrence of acute GVHD after unrelated, 12/12 HLA matched, hematopoietic stem cell transplantation.

KIR3DL1 KIR3DS1

6.70e-051725219169284
Pubmed

Association of KIR2DS1 and KIR2DS3 with fatal outcome in Ebola virus infection.

KIR3DL1 KIR3DS1

6.70e-051725220878400
Pubmed

Killer cell immunoglobulin-like receptor gene diversity in the Tibetan ethnic minority group of China.

KIR3DL1 KIR3DS1

6.70e-051725220650299
Pubmed

Killer cell immunoglobulin-like receptor gene polymorphisms in patients with leukemia: possible association with susceptibility to the disease.

KIR3DL1 KIR3DS1

6.70e-051725219450876
Pubmed

Distribution of killer-cell immunoglobulin-like receptor genes in Eastern mainland Chinese Han and Taiwanese Han populations.

KIR3DL1 KIR3DS1

6.70e-051725219761533
Pubmed

Combination of KIR 2DL2 and HLA-C1 (Asn 80) confers susceptibility to type 1 diabetes in Latvians.

KIR3DL1 KIR3DS1

7.54e-051825219046302
Pubmed

Effect of killer immunoglobulin-like receptors in the response to combined treatment in patients with chronic hepatitis C virus infection.

KIR3DL1 KIR3DS1

7.54e-051825219846535
Pubmed

Killer immunoglobulin-like receptor ligand HLA-Bw4 protects against multiple sclerosis.

KIR3DL1 KIR3DS1

7.54e-051825219630074
Pubmed

Influence of HLA class I and HLA-KIR compound genotypes on HIV-2 infection and markers of disease progression in a Manjako community in West Africa.

KIR3DL1 KIR3DS1

7.54e-051825220519398
Pubmed

Association of killer cell immunoglobulin-like receptors and human leukocyte antigen-C genotypes in South Brazilian with type 1 diabetes.

KIR3DL1 KIR3DS1

7.54e-051825220580654
Pubmed

Distribution of killer cell immunoglobulin-like receptor genes in the mestizo population from Venezuela.

KIR3DL1 KIR3DS1

7.54e-051825220210918
Pubmed

Association between killer-cell immunoglobulin-like receptor genotypes and leprosy in Brazil.

KIR3DL1 KIR3DS1

8.42e-051925218778326
Cytoband19q13.4

ZNF17 KIR3DL1 KIR3DS1

1.10e-057925319q13.4
CytobandEnsembl 112 genes in cytogenetic band chr2q14

SCTR PSD4

3.65e-03165252chr2q14
CytobandEnsembl 112 genes in cytogenetic band chr19q13

ZNF17 KIR3DL1 SHISA7 ZNF780B

3.70e-031192254chr19q13
CytobandEnsembl 112 genes in cytogenetic band chr3p21

ZKSCAN7 PTH1R

1.28e-02316252chr3p21
GeneFamilyParathyroid hormone receptors

PTH1R PTH2R

1.05e-062192270
GeneFamilyCD molecules|Killer cell immunoglobulin like receptors

KIR3DL1 KIR3DS1

1.58e-0418192620
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

RLF ZNF17 ZKSCAN7 ZNF780B

5.94e-0371819428
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

BTK PSD4

1.94e-02206192682
CoexpressionAtlasStem Cells, SC.STSL.BM, CD117+ IL7R- CD150- CD48- AA4.1+ CD43+, Bone marrow, avg-3

OCRL CUL7 MBOAT2 PTGS1 BTK

6.10e-05423225GSM399454_500
ToppCellTracheal-10x3prime_v2-Immune_Lymphocytic-B-B_cell-B_naive|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

SCTR FHOD1 BTK PSD4

2.46e-0710124486acaa2502f61baa714ae988b73e3e73a71e897e
ToppCellE18.5-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B-B_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SHISA7 BTK PSD4

8.77e-0516224359f6a9005c4f22f084c25ea36f3cacce5144a9ae
ToppCellcritical-Myeloid-Mast_cell|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

PTGS1 PTH2R BTK

9.26e-0516524334a1cc6ccd46c059354e8fbde1ac69f202695a4e
ToppCell5'-Parenchyma_lung-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells-Mast_cells_L.1.4.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PTGS1 BTK PSD4

9.43e-05166243a42268a02a89fc97272e45c4cbe21acf04b7428c
ToppCell5'-GW_trimst-2-SmallIntestine-Hematopoietic-Myeloid-CLC+_Mast_cell|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PTGS1 PTH2R BTK

1.05e-041722432ab720a4c96073339a1f8b95ec7699682df98acf
ToppCell11.5-Distal-Mesenchymal-Mesenchyme_SERPINF1-high|Distal / Age, Tissue, Lineage and Cell class

PHYHIP SCTR PTGS1

1.07e-041732436989c9cebcd81eccceac7e5a86152676ee959386
ToppCelldroplet-Liver-LIVER_HEP-30m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTGS1 SHISA7 BTK

1.12e-041762435e46a09a36b9645b1b1fcb0b64bd0898561af3a9
ToppCelldroplet-Liver-LIVER_HEP-30m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTGS1 SHISA7 BTK

1.14e-0417724314fb8d182775dfd0e49aa7e4e12543a85b3b8bd6
ToppCell368C-Myeloid-Macrophage-SPP1+_Macrophage_3|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

OCRL CUL7 PSD4

1.16e-041782439d575902d3dbe33437c9d4200df093a741269803
ToppCell368C-Myeloid-Macrophage-SPP1+_Macrophage_3|368C / Donor, Lineage, Cell class and subclass (all cells)

OCRL CUL7 PSD4

1.16e-04178243536a601abcc60867949ea06e9aafb6c7b799b56b
ToppCellTCGA-Liver-Primary_Tumor-Hepatocellular_Carcinoma-Hepatocellular_Carcinoma-1|TCGA-Liver / Sample_Type by Project: Shred V9

SCTR MBOAT2 ITPR3

1.16e-0417824351c59dabf2d7aef1b1964f6f766d5ec07ef90f5a
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PHYHIP BTK PSD4

1.20e-041802436ac62bf1251978c8c12e715f7b73144fca619794
ToppCell3'-GW_trimst-1-LargeIntestine-Hematopoietic-Myeloid-CLC+_Mast_cell|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PTGS1 PTH2R BTK

1.20e-041802431c5515f29ead129bee3b4ca27799796956811a39
ToppCellmetastatic_Brain-Myeloid_cells-CD207+CD1a+_LCs|metastatic_Brain / Location, Cell class and cell subclass

PHYHIP PTGS1 BTK

1.20e-0418024351727cb66fe7a7709453f7026e0ff3d6c93d5aa5
ToppCell5'-GW_trimst-2-LargeIntestine-Hematopoietic-Myeloid-CLC+_Mast_cell|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PTGS1 PTH2R BTK

1.22e-04181243338c7362d258a87f1a6b1a65376f5394d4b2b4b2
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

MBOAT2 PTGS1 PTH2R

1.24e-04182243205d9ad1ea4b7adee8054496cdde46c9c401a19a
ToppCellwk_08-11-Mesenchymal-Mesothelial-Late_mesothelial|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

PHYHIP SCTR PTGS1

1.24e-04182243f8257c884393f168f605d371e0840cfca8d3657e
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

MBOAT2 PTGS1 PTH2R

1.28e-04184243ca35a3d2b536c8b2bf5c4d635605e5a3ae94a428
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_mesothelial_(19)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

PHYHIP SCTR PTGS1

1.30e-04185243492529121cb9e88bd3c0db6b54af3cd2979572bc
ToppCellPCW_07-8.5-Hematologic_ErythroMegGranulo|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

PTGS1 PTH2R BTK

1.32e-04186243294839944266407c40ef86e1d3e0fce4652b70ff
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6-Exc_L6_THEMIS_EGR3|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

MBOAT2 PTGS1 PTH2R

1.32e-0418624377b09af860183606a1775eba921e2071e4a7dd4e
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SCTR PTH1R ITPR3

1.38e-04189243aadb7a2de4cbe7f0958651f2739bba430b93f5c1
ToppCell5'-Airway_Nasal-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells-Mast_cells_L.1.4.0.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PTGS1 SHISA7 BTK

1.38e-04189243aba941ba6ce7702418b3f470bde573d123c4aade
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SCTR PTH1R ITPR3

1.38e-041892438977f3295b7df7c7474b3f371de90a82ae4bb50c
ToppCellPCW_13-14-Hematologic_ErythroMegGranulo-Hem_Granulocytic-im_mast/basophil_(18)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

PTGS1 PTH2R BTK

1.43e-0419124314b11244c330cc4fe897253aaaf0df80caa01a55
ToppCellwk_15-18-Mesenchymal-Mesothelial|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

PHYHIP SCTR PTGS1

1.43e-04191243b5374674312ff5803a1d369f5533027532344679
ToppCellwk_08-11-Mesenchymal-Mesothelial-intermediate_mesothelial|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

PHYHIP SCTR PTGS1

1.45e-04192243ac9e5288ecd4b1e142f2e15a1fcd11c8eb9e15cd
ToppCell5'-Airway_Nasal-Immune_Myeloid_mast|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PTGS1 SHISA7 BTK

1.45e-04192243e0412964a3ee1bf3c0ef64f9a6f20f7e7835701e
ToppCell5'-Airway_Nasal-Immune_Myeloid_mast-Myeloid_Mast/Baso|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PTGS1 SHISA7 BTK

1.45e-04192243690cf19e9b0b2ada80097c63eae827529aa5b6f3
ToppCell5'-Airway_Nasal-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PTGS1 SHISA7 BTK

1.45e-04192243b5871247a5f3e970fa05b33fff21bef9d2ab5741
ToppCell5'-Airway_Nasal-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PTGS1 SHISA7 BTK

1.45e-041922433d6c4c5847ca1e44fa380403d25af45d5b51ee9b
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SCTR PTH1R ITPR3

1.47e-04193243f42a0f02ed00fe1bb833ff0a0640d9131bca89bd
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SCTR PTH1R ITPR3

1.47e-0419324342df7ed37d11fb542b4d1d714b6f87ae8e1396a6
ToppCell5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.0.3|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SCTR GUCD1 ITPR3

1.47e-041932438646e573f2d2ff175f3d02bfdf214e65f3b614d3
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SCTR PTH1R ITPR3

1.52e-04195243938b31dbf1674ee6fd0123bc88391ddcaf151217
ToppCellwk_08-11-Mesenchymal-Mesothelial|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

PHYHIP SCTR PTGS1

1.52e-041952439016a44b521214546a55a822ebdef5b5312206d2
ToppCellPrimary_Visual_cortex_(V1C)|World / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PHYHIP PTGS1 PSD4

1.52e-0419524324dbb125565facd2de42d848471d4867c81acf80
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SCTR PTH1R ITPR3

1.52e-04195243d39e9e6544f49e677ebe528c6fe60b99a3630e30
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SCTR PTH1R ITPR3

1.63e-0420024355b7b17f2d413b9ebb262ef8bd210ef45618a7f3
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SCTR PTH1R ITPR3

1.63e-04200243741e59c68ae4a3a7be830e98771a14f920c9e883
ToppCellTracheal-10x3prime_v2-Stromal-Pericyte-Muscle_pericyte_systemic|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

SCTR B3GNT4

6.63e-04712425d63a582229520b2a037f3c27f772e34cdee092b
ToppCellmild-immature_Neutrophil|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

MBOAT2 ZNF780B

9.04e-0483242f7225bc24ad6df3a41375cc4614af824e0db3559
ToppCellmild-immature_Neutrophil|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

MBOAT2 ZNF780B

1.55e-031092422f03d6ee8b13424cc6a5bc60ac3461b44dff9d79
ToppCellBronchial-10x5prime-Stromal-Schwann-Schwann_nonmyelinating|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

OCRL MBOAT2

1.75e-03116242b0a3c109c5f20ab699e53bf8ab3903d102f5f315
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_1-Airway|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

B3GNT4 PTGS1

1.81e-031182428d96a4879b28979fa04fbaeffa271a6b9ecbe867
ToppCellHippocampus-Macroglia-POLYDENDROCYTE-P1-P1_1|Hippocampus / BrainAtlas - Mouse McCarroll V32

ZKSCAN7 PTH2R

1.84e-031192420dd72dbded7ade911612d20e0c6e3f40e85fc890
ToppCellHippocampus-Macroglia-POLYDENDROCYTE-P1-P1_1-Trf-Oligodendrocyte.Trf.Ctps_(Ctps)|Hippocampus / BrainAtlas - Mouse McCarroll V32

ZKSCAN7 PTH2R

1.84e-031192420c9aff5442a1b1e51e142d6527d5a48211d94335
ToppCellHippocampus-Macroglia-POLYDENDROCYTE-P1-P1_1-Trf|Hippocampus / BrainAtlas - Mouse McCarroll V32

ZKSCAN7 PTH2R

1.84e-031192427367b6e4906d234ca864075443efe420ee407421
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L6b-L6b_VISp_Col8a1_Rprm|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PTH2R PSD4

1.87e-031202422b7596946f9268c4202348adf3069decd8313bb0
ToppCell|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PTGS1 BTK

1.90e-03121242da8fe561dcf50792d0cbcaad383d564f900a6677
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Pvalb-Pvalb_Th_Sst|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PTGS1 PSD4

2.06e-031262423a14d4eb8803827946c36faeeb7ae2913418d421
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L6b-L6b_ALM_Olfr111_Spon1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PTH2R PSD4

2.09e-03127242cd69ba386796715e87674f8324d2acaad1d4d094
ToppCellsevere-unassigned|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

KIR3DL1 MBOAT2

2.13e-03128242bef9cf0078fa8498d63f0723f1fa4a3c92405e10
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6b-L6b_VISp_Col8a1_Rxfp1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PTH2R PSD4

2.23e-0313124281efe8b0ca4377e557a42ddb12aecaf3f46b15bf
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6b-L6b_VISp_Col8a1_Rprm|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PTH2R PSD4

2.26e-0313224266ec5a06eece27c0aafb548f51db9fee595e71bc
ToppCellLPS-IL1RA+antiTNF-Hematopoietic_Mast-Mast_cells-Mast-cells|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PTGS1 BTK

2.29e-0313324281189e8516a431d5890a0909f9fc7c82ec3442bc
ToppCellFetal_29-31_weeks-Immune-mast_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

PTGS1 BTK

2.33e-031342421d6e74612fd91a2ef9d14bf77262b2d08e1052ca
ToppCellLPS_only-Hematopoietic_Mast-Mast_cells-Mast-cells|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PTGS1 BTK

2.40e-0313624282d7f90ef2a63a3137c331efd68c036cd0db3ac1
ToppCellFrontal_cortex-Hematopoietic-MICROGLIA-MI1(C1qb)-Tmem119|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

BTK PSD4

2.54e-031402422c04fa782aa076e4be8a2781aa04231180bd69bd
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L6b|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PTH2R PSD4

2.54e-0314024217005ca714ba03d7528fe7979ffb4654a46b666c
ToppCellFrontal_cortex-Hematopoietic-MICROGLIA-MI1(C1qb)-Tmem119-MICROGLIA_Microglia.C1qb.Tmem119-Fos_(Microglia.C1qb.Tmem119-Fos)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

BTK PSD4

2.54e-03140242a9389a6e55d02d5037868c9ecce48b5e8d7c2902
ToppCellFrontal_cortex-Hematopoietic-MICROGLIA-MI1(C1qb)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

BTK PSD4

2.54e-031402428db98a17a4d4b42dbfc75e9cdaa22275fed4f2f0
ToppCellFrontal_cortex-Hematopoietic-MICROGLIA-MI1(C1qb)-Tmem119-MICROGLIA_Microglia.C1qb.Tmem119-Fos_(Microglia.C1qb.Tmem119-Fos)-|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

BTK PSD4

2.54e-0314024222098203361f61b9f0ce9f0f2d1369d8bb1379a8
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6b|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PTH2R PSD4

2.57e-031412425ef3166c5271aa90fd0633016edfe2c74b835319
ToppCellControl-Hematopoietic_Mast-Mast_cells|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PTGS1 BTK

2.61e-03142242a81f7ea4516a869c7c9b9a3f4ef74844ff9fffcd
ToppCellControl-Hematopoietic_Mast-Mast_cells-T-cells|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PTGS1 BTK

2.61e-0314224270f8c1be134835e0d21e6d426b7122f0f5d3d3e5
ToppCellPBMC-Mild-cDC_7|Mild / Compartment, Disease Groups and Clusters

PTGS1 ITPR3

2.61e-0314224258f66f35646f281e64d634e6c26adbd1d4e6c830
ToppCellControl-Hematopoietic_Mast|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PTGS1 BTK

2.61e-03142242db9b7acbab730ae391a362f1ca8177507e52250d
ToppCell3'_v3-blood-Lymphocytic_Invariant-Inducer-like-MAIT|blood / Manually curated celltypes from each tissue

B3GNT4 ITPR3

2.61e-031422421175d4390d204ffa3a2d2fe24486f85d3b639b72
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SCTR PSD4

2.64e-031432427a7a9829ba63468c9745904d9e993590051207ab
ToppCellP03-Hematopoietic-Erythroid-enucleate_erythrocyte|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

PHYHIP BTK

2.68e-031442429fa63904389f4d7163db22ea85ab721d8f6e8d99
ToppCellP07-Hematopoietic-Immune-immune_cell_unspecified|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

BTK PSD4

2.68e-03144242eb057dbdb2a5a2d29b93e5ed5479a3fd1bf3fd26
ToppCellP03-Hematopoietic-Erythroid|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

PHYHIP BTK

2.68e-031442422ee6a834860eac7ed004f366ab4fc38c4b80c905
ToppCellLPS-antiTNF-Hematopoietic_Mast-Mast_cells-Mast-cells|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PTGS1 BTK

2.68e-03144242013223bb2f31eb5bebdbd0908b797d28b96c6f7b
ToppCellP07-Hematopoietic-Immune|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

BTK PSD4

2.68e-03144242962698c5c15bd583fccda0593b7aab5f2eb4bc9f
ToppCellFetal_29-31_weeks-Immune-mast_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

PTGS1 BTK

2.72e-03145242dc89d817a9bef24a07e992efdab4136f12ceb399
ToppCellCOVID-19-Mast_cells-Transitioning_MDM|COVID-19 / group, cell type (main and fine annotations)

ZNF17 PTH2R

2.72e-031452425c5fed4620c4c312d1052b8acad910453f7e8fcc
ToppCell10x_3'_v3-lymph_node_(10x_3'_v3)-hematologic|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

SHISA7 PTH1R

2.75e-0314624203a6a442f1f6d173a41aeebbfe41ee08853d9585
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Pvalb-Pvalb_Calb1_Sst|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PTGS1 PTH1R

2.75e-0314624210839a4fce2e62955a90592f927a6e0c6a84bbad
ToppCellPosterior_cortex-Hematopoietic-MICROGLIA-MI1(C1qb)-Tmem119-MICROGLIA_Microglia.C1qb.Tmem119-Fos_(Microglia)-|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

FHOD1 BTK

2.87e-03149242406a5ccfedbf43543f0346ff7ef3ce1d15c38f29
ToppCellPosterior_cortex-Hematopoietic-MICROGLIA-MI1(C1qb)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

FHOD1 BTK

2.87e-0314924234a3075af794052763fc7c4135f3031f89da5caa
ToppCellPosterior_cortex-Hematopoietic-MICROGLIA-MI1(C1qb)-Tmem119|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

FHOD1 BTK

2.87e-03149242be698ecce34ddbdf57d08082b71268934675e74e
ToppCellPosterior_cortex-Hematopoietic-MICROGLIA-MI1(C1qb)-Tmem119-MICROGLIA_Microglia.C1qb.Tmem119-Fos_(Microglia)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

FHOD1 BTK

2.87e-03149242183c77cc8f23b8406e7241a066cb684470002a3b
ToppCellPCW_05-06-Hematologic_ErythroMegGranulo-Hem_ErythroMeg-im_megakaryocyte2_(17)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

PTGS1 BTK

2.90e-031502426d65df8c0937b498585d1e79919ec73daa354e21
ToppCellTCGA-Kidney|World / Sample_Type by Project: Shred V9

PTH1R PTH2R

2.94e-03151242e31974c0d0a0c644205a0ee6013ab74a09d8a306
ToppCellHippocampus-Hematopoietic|Hippocampus / BrainAtlas - Mouse McCarroll V32

BTK PSD4

2.94e-0315124281b2189afd72658f7e2539b856ba79cd49340215
ToppCell368C-Myeloid-Mast_cell|368C / Donor, Lineage, Cell class and subclass (all cells)

PTGS1 BTK

2.98e-03152242faf30245a1690aaa27c7be0832797c340e4af4d7
ToppCellTracheal-10x3prime_v2-Immune_Myeloid-Mast_cell-Mast_cell|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

PTGS1 BTK

2.98e-03152242321d322d58c12fd752de4e8ea873f3f367302813
ToppCellTracheal-10x3prime_v2-Immune_Myeloid-Mast_cell|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

PTGS1 BTK

2.98e-03152242a4d50e9af02231c5573aee905cf0905391e6da34
ToppCell368C-Myeloid-Mast_cell-|368C / Donor, Lineage, Cell class and subclass (all cells)

PTGS1 BTK

2.98e-03152242519c9ed05fdaf420e42147ffae1dc05a7f86fdd4
ToppCellfacs-Large_Intestine-Distal-3m-Epithelial-Brush_cell_of_epithelium_proper_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCTR PTGS1

3.02e-031532423b1b0cc8e9dd2b1484649789330713282ee44414
ToppCell368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

KIR3DL1 ZNF780B

3.06e-03154242ba55a63cfa5e0fb9dfec794f80078a2f0d03d0ad
ToppCell390C-Lymphocytic-NK_cells-NK_cell_E|390C / Donor, Lineage, Cell class and subclass (all cells)

ZKSCAN7 CUL7

3.10e-0315524298d8432739965dd1ab77c899cb6321f7f05eaa46
ToppCellCOVID-19-Mast_cells-Mast_cells|COVID-19 / group, cell type (main and fine annotations)

PTGS1 PTH2R

3.14e-03156242bc10b94673184ef384c6665b16a1209a8975a4f1
ToppCellE18.5-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

BTK PSD4

3.14e-0315624255ba43cec9d79f309e9f633a6469cf03bb621e64
ToppCellCOVID-19-Mast_cells|COVID-19 / group, cell type (main and fine annotations)

PTGS1 PTH2R

3.14e-03156242159504d43421ee83b9ab484816333ae549c9c2fd
ToppCellChildren_(3_yrs)-Mesenchymal-chondrocyte-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

PTH1R ITPR3

3.14e-0315624260f1ce38e34b582f589db1e0d6139282c1902b2b
ToppCellPCW_10-12-Hematologic_ErythroMegGranulo-Hem_ErythroMeg-im_megakaryocyte1_(20)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

PTGS1 BTK

3.14e-03156242c380142e49b1e4ecacbf37587aafa57f8562b6ad
ToppCell10x5'-Lung-Lymphocytic_T_CD4/8-lo-Tgd_CRTAM|Lung / Manually curated celltypes from each tissue

KIR3DL1 ITPR3

3.14e-031562420ea6ca3f38109151a2a4fdf63a4f009929cdcc40
ToppCellNS-moderate-d_07-13-Myeloid-Mast_cell|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

PTGS1 BTK

3.14e-0315624217c38d3b03fc38cb125cf0d165b2fd694cd88edd
Drugiodine atom

KIR3DL1 PTGS1 MITD1

1.12e-0619253CID005360629
Drugbp 16

PTH1R PTH2R

1.16e-055252CID000127325
Drugbenzophenone

SCTR PTH1R PTH2R

1.84e-0547253CID000003102
DrugY-27632; Up 200; 3uM; MCF7; HT_HG-U133A_EA

CUL7 OGFR FHOD1 PSD4

5.51e-05193254948_UP
DrugMemantine Hydrochloride [41100-52-1]; Down 200; 18.6uM; MCF7; HT_HG-U133A

CUL7 OGFR ITPR3 PSD4

5.62e-051942547354_DN
DrugAlfuzosin hydrochloride [81403-68-1]; Down 200; 9.4uM; PC3; HT_HG-U133A

OCRL OGFR FHOD1 ITPR3

5.73e-051952544644_DN
DrugGlycocholic acid [475-31-0]; Down 200; 8.6uM; MCF7; HT_HG-U133A

B3GNT4 MBOAT2 OGFR PSD4

5.73e-051952543315_DN
DrugEthoxyquin [91-53-2]; Up 200; 18.4uM; PC3; HT_HG-U133A

PHYHIP B3GNT4 OGFR PTH2R

5.85e-051962544321_UP
DrugMimosine [500-44-7]; Up 200; 20.2uM; MCF7; HT_HG-U133A

OGFR PTGS1 NTN3 PSD4

6.08e-051982542638_UP
DrugPhenelzine sulfate [156-51-4]; Up 200; 17uM; PC3; HT_HG-U133A

PTGS1 PTH2R NTN3 ITPR3

6.08e-051982543802_UP
DrugBisoprolol fumarate; Up 200; 9uM; PC3; HT_HG-U133A

PHYHIP B3GNT4 OGFR ITPR3

6.08e-051982546748_UP
DrugTacrine hydrochloride hydrate [1684-40-8]; Down 200; 15.8uM; HL60; HT_HG-U133A

OCRL CUL7 FHOD1 PSD4

6.32e-052002541278_DN
Diseasemalaria (is_implicated_in)

KIR3DL1 KIR3DS1

1.19e-0424202DOID:12365 (is_implicated_in)
Diseasetuberculosis (is_implicated_in)

KIR3DL1 KIR3DS1

1.63e-0428202DOID:399 (is_implicated_in)
Diseasehepatitis C (is_implicated_in)

KIR3DL1 KIR3DS1

1.63e-0428202DOID:1883 (is_implicated_in)
Diseasehuman immunodeficiency virus infectious disease (is_implicated_in)

KIR3DL1 KIR3DS1

3.19e-0439202DOID:526 (is_implicated_in)
DiseaseDisproportionate short stature

CUL7 PTH1R

1.24e-0377202C0878659

Protein segments in the cluster

PeptideGeneStartEntry
CFYIHAKMRQEHRNR

DDX6

361

P26196
CLLNYLREMRHRFQT

BTK

481

Q06187
HMFRLCYRVLRHSQE

ITPR3

551

Q14573
LAARAMRNNFRHYFI

MBOAT2

391

Q6ZWT7
TLRCHYRHRFNNFML

KIR3DL1

46

P43629
LCRHTRLFYMVRAQA

CUL7

981

Q14999
QYRNRIAMEFNHLYH

PTGS1

371

P23219
HARRCRFNMELYRLS

NTN3

316

O00634
LAYLMHHFGVRHRFC

GUCD1

71

Q96NT3
SRHRLFLTYRHCRNF

B3GNT4

91

Q9C0J1
VHRRVCNRFHAFLLY

FHOD1

946

Q9Y613
YFMFAVRCRHQRRQL

OGFR

256

Q9NZT2
RHTHQLYNFLRFCEM

MITD1

126

Q8WV92
TLRCHYRHRFNNFML

KIR3DS1

46

Q14943
ERILYQFSRRFHHCN

PSD4

656

Q8NDX1
HYRFCCEHRHMRLAQ

SHISA7

111

A6NL88
AGRMLRFSVFYRNHH

PHYHIP

131

Q92561
CHRNVFRYLMAFLRE

OCRL

831

Q01968
CTYCRRHFMSAFHLR

RLF

716

Q13129
YFRRLHCTRNYIHMH

PTH1R

211

Q03431
AFRRLHCTRNYIHMH

SCTR

166

P47872
EMAFRYHYQLIEHCR

ZNF780B

311

Q9Y6R6
RLHCTRNYIHMHLFV

PTH2R

171

P49190
EIFRLHFRQLCYHEM

ZKSCAN7

51

Q9P0L1
FRYCFTLNRHQRVHS

ZNF17

451

P17021