Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	complement component C3b receptor activity	CR1 CR1L	5.42e-06	2	47	2	GO:0004877
GeneOntologyMolecularFunction	complement component C4b receptor activity	CR1 CR1L	5.42e-06	2	47	2	GO:0001861
GeneOntologyMolecularFunction	alpha-L-arabinofuranosidase activity	OTOGL OTOG	5.42e-06	2	47	2	GO:0046556
GeneOntologyMolecularFunction	complement component C4b binding	CR1 CR1L	1.62e-05	3	47	2	GO:0001855
GeneOntologyMolecularFunction	opsonin receptor activity	CR1 CR1L	1.50e-04	8	47	2	GO:0001847
GeneOntologyMolecularFunction	complement component C3b binding	CR1 CR1L	3.53e-04	12	47	2	GO:0001851
GeneOntologyMolecularFunction	complement receptor activity	CR1 CR1L	4.85e-04	14	47	2	GO:0004875
GeneOntologyMolecularFunction	opsonin binding	CR1 CR1L	1.57e-03	25	47	2	GO:0001846
GeneOntologyMolecularFunction	Notch binding	DLK2 NOTCH1	1.83e-03	27	47	2	GO:0005112
GeneOntologyMolecularFunction	complement binding	CR1 CR1L	2.57e-03	32	47	2	GO:0001848
GeneOntologyBiologicalProcess	negative regulation of complement activation, classical pathway	CR1 CR1L SVEP1	6.16e-07	8	47	3	GO:0045959
GeneOntologyBiologicalProcess	regulation of complement activation, classical pathway	CR1 CR1L SVEP1	1.32e-06	10	47	3	GO:0030450
GeneOntologyBiologicalProcess	negative regulation of humoral immune response mediated by circulating immunoglobulin	CR1 CR1L SVEP1	2.40e-06	12	47	3	GO:0002924
GeneOntologyBiologicalProcess	complement activation, classical pathway	C1S CR1 CR1L SVEP1	3.00e-06	44	47	4	GO:0006958
GeneOntologyBiologicalProcess	negative regulation of complement activation	CR1 CR1L SVEP1	3.97e-06	14	47	3	GO:0045916
GeneOntologyBiologicalProcess	arabinose metabolic process	OTOGL OTOG	5.08e-06	2	47	2	GO:0019566
GeneOntologyBiologicalProcess	vibrational conductance of sound to the inner ear	OTOGL OTOG	5.08e-06	2	47	2	GO:0055127
GeneOntologyBiologicalProcess	L-arabinose metabolic process	OTOGL OTOG	5.08e-06	2	47	2	GO:0046373
GeneOntologyBiologicalProcess	negative regulation of B cell mediated immunity	CR1 CR1L SVEP1	6.08e-06	16	47	3	GO:0002713
GeneOntologyBiologicalProcess	negative regulation of immunoglobulin mediated immune response	CR1 CR1L SVEP1	6.08e-06	16	47	3	GO:0002890
GeneOntologyBiologicalProcess	negative regulation of humoral immune response	CR1 CR1L SVEP1	1.05e-05	19	47	3	GO:0002921
GeneOntologyBiologicalProcess	humoral immune response mediated by circulating immunoglobulin	C1S CR1 CR1L SVEP1	1.20e-05	62	47	4	GO:0002455
GeneOntologyBiologicalProcess	regulation of humoral immune response mediated by circulating immunoglobulin	CR1 CR1L SVEP1	1.66e-05	22	47	3	GO:0002923
GeneOntologyBiologicalProcess	complement activation	C1S CR1 CR1L SVEP1	1.94e-05	70	47	4	GO:0006956
GeneOntologyBiologicalProcess	regulation of complement activation	CR1 CR1L SVEP1	3.12e-05	27	47	3	GO:0030449
GeneOntologyBiologicalProcess	insulin-like growth factor receptor signaling pathway	IGFBP3 CRIM1 ZFAND2B	3.46e-04	60	47	3	GO:0048009
GeneOntologyBiologicalProcess	regulation of humoral immune response	CR1 CR1L SVEP1	3.46e-04	60	47	3	GO:0002920
GeneOntologyBiologicalProcess	regulation of complement-dependent cytotoxicity	CR1 CR1L	3.90e-04	13	47	2	GO:1903659
GeneOntologyBiologicalProcess	pentose metabolic process	OTOGL OTOG	3.90e-04	13	47	2	GO:0019321
GeneOntologyBiologicalProcess	positive regulation of platelet activation	SELP SVEP1	4.54e-04	14	47	2	GO:0010572
GeneOntologyBiologicalProcess	negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	CR1 CR1L SVEP1	4.59e-04	66	47	3	GO:0002823
GeneOntologyBiologicalProcess	negative regulation of adaptive immune response	CR1 CR1L SVEP1	5.69e-04	71	47	3	GO:0002820
GeneOntologyBiologicalProcess	complement-dependent cytotoxicity	CR1 CR1L	5.98e-04	16	47	2	GO:0097278
GeneOntologyBiologicalProcess	regulation of B cell mediated immunity	CR1 CR1L SVEP1	7.77e-04	79	47	3	GO:0002712
GeneOntologyBiologicalProcess	regulation of immunoglobulin mediated immune response	CR1 CR1L SVEP1	7.77e-04	79	47	3	GO:0002889
GeneOntologyBiologicalProcess	humoral immune response	C1S CR1 CR1L SVEP1 NOTCH1	7.95e-04	321	47	5	GO:0006959
Domain	Sushi	SELP C1S APOH CR1 CR1L CSMD3 SVEP1	3.57e-11	52	45	7	PF00084
Domain	CCP	SELP C1S APOH CR1 CR1L CSMD3 SVEP1	4.70e-11	54	45	7	SM00032
Domain	SUSHI	SELP C1S APOH CR1 CR1L CSMD3 SVEP1	6.14e-11	56	45	7	PS50923
Domain	Sushi_SCR_CCP_dom	SELP C1S APOH CR1 CR1L CSMD3 SVEP1	6.98e-11	57	45	7	IPR000436
Domain	VWC_out	FCGBP CRIM1 SSPOP OTOG	1.11e-07	19	45	4	SM00215
Domain	EGF_3	SELP DLK2 C1S SSPOP SVEP1 NOTCH1 OTOG	1.38e-06	235	45	7	PS50026
Domain	EGF-like_dom	SELP DLK2 C1S FCGBP SVEP1 NOTCH1 OTOG	2.03e-06	249	45	7	IPR000742
Domain	TIL	FCGBP SSPOP OTOG	2.83e-06	12	45	3	PF01826
Domain	C8	FCGBP SSPOP OTOG	2.83e-06	12	45	3	PF08742
Domain	VWF_dom	FCGBP CRIM1 SSPOP OTOG	3.08e-06	42	45	4	IPR001007
Domain	Unchr_dom_Cys-rich	FCGBP SSPOP OTOG	3.68e-06	13	45	3	IPR014853
Domain	C8	FCGBP SSPOP OTOG	3.68e-06	13	45	3	SM00832
Domain	TIL_dom	FCGBP SSPOP OTOG	4.67e-06	14	45	3	IPR002919
Domain	VWD	FCGBP SSPOP OTOG	7.16e-06	16	45	3	SM00216
Domain	VWF_type-D	FCGBP SSPOP OTOG	7.16e-06	16	45	3	IPR001846
Domain	VWFD	FCGBP SSPOP OTOG	7.16e-06	16	45	3	PS51233
Domain	VWD	FCGBP SSPOP OTOG	7.16e-06	16	45	3	PF00094
Domain	EGF	SELP DLK2 C1S SVEP1 NOTCH1	1.27e-05	126	45	5	PF00008
Domain	EGF_1	SELP DLK2 C1S SSPOP SVEP1 NOTCH1	3.18e-05	255	45	6	PS00022
Domain	Growth_fac_rcpt_	IGFBP3 CRIM1 KRT32 SVEP1 NOTCH1	3.56e-05	156	45	5	IPR009030
Domain	EGF_2	SELP DLK2 C1S SSPOP SVEP1 NOTCH1	3.95e-05	265	45	6	PS01186
Domain	hEGF	DLK2 SVEP1 NOTCH1	4.10e-05	28	45	3	PF12661
Domain	EGF_Ca-bd_CS	DLK2 C1S SVEP1 NOTCH1	8.65e-05	97	45	4	IPR018097
Domain	EGF_CA	DLK2 C1S SVEP1 NOTCH1	9.37e-05	99	45	4	PS01187
Domain	ASX_HYDROXYL	DLK2 C1S SVEP1 NOTCH1	9.74e-05	100	45	4	PS00010
Domain	VWC	FCGBP CRIM1 SSPOP	1.04e-04	38	45	3	SM00214
Domain	EGF-type_Asp/Asn_hydroxyl_site	DLK2 C1S SVEP1 NOTCH1	1.22e-04	106	45	4	IPR000152
Domain	-	ZFAND2A ZFAND2B	1.57e-04	8	45	2	4.10.1110.10
Domain	zf-AN1	ZFAND2A ZFAND2B	1.57e-04	8	45	2	PF01428
Domain	ZF_AN1	ZFAND2A ZFAND2B	1.57e-04	8	45	2	PS51039
Domain	Znf_AN1	ZFAND2A ZFAND2B	1.57e-04	8	45	2	IPR000058
Domain	ZnF_AN1	ZFAND2A ZFAND2B	1.57e-04	8	45	2	SM00154
Domain	EGF_CA	DLK2 C1S SVEP1 NOTCH1	2.10e-04	122	45	4	SM00179
Domain	EGF-like_Ca-bd_dom	DLK2 C1S SVEP1 NOTCH1	2.23e-04	124	45	4	IPR001881
Domain	EGF	SELP DLK2 FCGBP SVEP1 NOTCH1	2.45e-04	235	45	5	SM00181
Domain	EGF-like_CS	SELP DLK2 C1S SVEP1 NOTCH1	3.97e-04	261	45	5	IPR013032
Domain	EGF_extracell	DLK2 SVEP1 NOTCH1	4.06e-04	60	45	3	IPR013111
Domain	EGF_2	DLK2 SVEP1 NOTCH1	4.06e-04	60	45	3	PF07974
Domain	BBOX	TRIM47 TRIM56 TRIM10	6.13e-04	69	45	3	SM00336
Domain	zf-B_box	TRIM47 TRIM56 TRIM10	6.94e-04	72	45	3	PF00643
Domain	IB	IGFBP3 CRIM1	8.47e-04	18	45	2	SM00121
Domain	ZF_BBOX	TRIM47 TRIM56 TRIM10	9.43e-04	80	45	3	PS50119
Domain	Znf_B-box	TRIM47 TRIM56 TRIM10	9.78e-04	81	45	3	IPR000315
Domain	IGFBP-like	IGFBP3 CRIM1	1.05e-03	20	45	2	IPR000867
Domain	IGFBP	IGFBP3 CRIM1	1.05e-03	20	45	2	PF00219
Domain	IGFBP_N_2	IGFBP3 CRIM1	1.05e-03	20	45	2	PS51323
Domain	EGF_CA	C1S SVEP1 NOTCH1	1.16e-03	86	45	3	PF07645
Domain	Cys_knot_C	SSPOP OTOG	1.64e-03	25	45	2	IPR006207
Domain	CTCK_2	SSPOP OTOG	1.64e-03	25	45	2	PS01225
Domain	VWFC_1	CRIM1 SSPOP	3.39e-03	36	45	2	PS01208
Domain	VWFC_2	CRIM1 SSPOP	3.78e-03	38	45	2	PS50184
Domain	PRY	TRIM47 TRIM10	5.97e-03	48	45	2	SM00589
Domain	PRY	TRIM47 TRIM10	5.97e-03	48	45	2	IPR006574
Domain	RING	G2E3 TRIM47 TRIM56 TRIM10	6.14e-03	305	45	4	SM00184
Pubmed	Complement-dependent P-selectin expression and injury following ischemic stroke.	SELP CR1 CR1L	2.31e-08	5	47	3	17082645
Pubmed	Mouse kalinin B1 (laminin beta 3 chain): cloning and tissue distribution.	SELP CR1 CR1L	1.29e-07	8	47	3	7898049
Pubmed	Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins.	SELP CR1 CR1L MUSK NOTCH1	2.60e-07	101	47	5	23382219
Pubmed	A Human Hereditary Cardiomyopathy Shares a Genetic Substrate With Bicuspid Aortic Valve.	CEP192 ASXL3 NOTCH1	6.55e-07	13	47	3	36325906
Pubmed	Functional identification of transcription control sequences of the mouse Crry gene.	CR1 CR1L	1.79e-06	2	47	2	8335915
Pubmed	Crry/p65, a membrane complement regulatory protein, has costimulatory properties on mouse T cells.	CR1 CR1L	1.79e-06	2	47	2	10779754
Pubmed	Astrocyte-specific expression of a soluble form of the murine complement control protein Crry confers demyelination protection in the cuprizone model.	CR1 CR1L	1.79e-06	2	47	2	17674370
Pubmed	Altered renal tubular expression of the complement inhibitor Crry permits complement activation after ischemia/reperfusion.	CR1 CR1L	1.79e-06	2	47	2	16444293
Pubmed	Different Expression Levels of DLK2 Inhibit NOTCH Signaling and Inversely Modulate MDA-MB-231 Breast Cancer Tumor Growth In Vivo.	DLK2 NOTCH1	1.79e-06	2	47	2	35163478
Pubmed	Distinct receptor and regulatory properties of recombinant mouse complement receptor 1 (CR1) and Crry, the two genetic homologues of human CR1.	CR1 CR1L	1.79e-06	2	47	2	1730912
Pubmed	Mesangial cell complement receptor 1-related protein y limits complement-dependent neutrophil accumulation in immune complex glomerulonephritis.	CR1 CR1L	1.79e-06	2	47	2	19740350
Pubmed	Complement inhibitor, complement receptor 1-related gene/protein y-Ig attenuates intestinal damage after the onset of mesenteric ischemia/reperfusion injury in mice.	CR1 CR1L	1.79e-06	2	47	2	11698469
Pubmed	Expression of a Crry/p65 is reduced in acute lung injury induced by extracellular histones.	CR1 CR1L	1.79e-06	2	47	2	34709768
Pubmed	The murine complement regulator Crry: new insights into the immunobiology of complement regulation.	CR1 CR1L	1.79e-06	2	47	2	11915940
Pubmed	Mouse Crry/p65. Characterization of monoclonal antibodies and the tissue distribution of a functional homologue of human MCP and DAF.	CR1 CR1L	1.79e-06	2	47	2	7691944
Pubmed	The murine complement receptor gene family. Analysis of mCRY gene products and their homology to human CR1.	CR1 CR1L	1.79e-06	2	47	2	2911011
Pubmed	Severe neonatal presentation of Kleefstra syndrome in a patient with hypoplastic left heart syndrome and 9q34.3 microdeletion.	EHMT1 NOTCH1	1.79e-06	2	47	2	25380126
Pubmed	Prevention of collagen-induced arthritis in mice transgenic for the complement inhibitor complement receptor 1-related gene/protein y.	CR1 CR1L	1.79e-06	2	47	2	12902517
Pubmed	Cutting edge: treatment of complement regulatory protein deficiency by retroviral in vivo gene therapy.	CR1 CR1L	1.79e-06	2	47	2	17015675
Pubmed	Deletion of Crry, the murine ortholog of the sporadic Alzheimer's disease risk gene CR1, impacts tau phosphorylation and brain CFH.	CR1 CR1L	1.79e-06	2	47	2	23153828
Pubmed	Expansion of the complement receptor gene family. Identification in the mouse of two new genes related to the CR1 and CR2 gene family.	CR1 CR1L	1.79e-06	2	47	2	2952719
Pubmed	Central nervous system-targeted complement inhibition mediates neuroprotection after closed head injury in transgenic mice.	CR1 CR1L	1.79e-06	2	47	2	12973023
Pubmed	Central nervous system-targeted expression of the complement inhibitor sCrry prevents experimental allergic encephalomyelitis.	CR1 CR1L	1.79e-06	2	47	2	10586048
Pubmed	In vivo correction of complement regulatory protein deficiency with an inhibitor targeting the red blood cell membrane.	CR1 CR1L	1.79e-06	2	47	2	16301687
Pubmed	Similar phenotypes caused by mutations in OTOG and OTOGL.	OTOGL OTOG	1.79e-06	2	47	2	24378291
Pubmed	Expression dynamics of Crry at the implantation sites in normal pregnancy and response against miscarriage induction.	CR1 CR1L	1.79e-06	2	47	2	36450590
Pubmed	Complement regulatory protein Crry/p65-mediated signaling in T lymphocytes: role of its cytoplasmic domain and partitioning into lipid rafts.	CR1 CR1L	1.79e-06	2	47	2	16301324
Pubmed	The extended multidomain solution structures of the complement protein Crry and its chimeric conjugate Crry-Ig by scattering, analytical ultracentrifugation and constrained modelling: implications for function and therapy.	CR1 CR1L	1.79e-06	2	47	2	12767833
Pubmed	The murine complement receptor gene family. III. The genomic and transcriptional complexity of the Crry and Crry-ps genes.	CR1 CR1L	1.79e-06	2	47	2	2307848
Pubmed	Complement regulatory protein Crry/p65 costimulation expands natural treg cells with enhanced suppressive properties in proteoglycan-induced arthritis.	CR1 CR1L	1.79e-06	2	47	2	21380996
Pubmed	Regulation of complement activity via the alternative pathway in placentas of mouse spontaneous abortions.	CR1 CR1L	1.79e-06	2	47	2	20484840
Pubmed	Duplication and divergence of the amino-terminal coding region of the complement receptor 1 (CR1) gene. An example of concerted (horizontal) evolution within a gene.	CR1 CR1L	5.36e-06	3	47	2	2295627
Pubmed	The Impact of Complement Genes on the Risk of Late-Onset Alzheimer's Disease.	C1S CR1	5.36e-06	3	47	2	33804666
Pubmed	Tissue-specific deletion of Crry from mouse proximal tubular epithelial cells increases susceptibility to renal ischemia-reperfusion injury.	CR1 CR1L	5.36e-06	3	47	2	24850152
Pubmed	Transgenic expression of a soluble complement inhibitor protects against renal disease and promotes survival in MRL/lpr mice.	CR1 CR1L	5.36e-06	3	47	2	11907125
Pubmed	Murine complement receptor gene family. II. Identification and characterization of the murine homolog (Cr2) to human CR2 and its molecular linkage to Crry.	CR1 CR1L	5.36e-06	3	47	2	2528587
Pubmed	Mouse complement regulatory protein Crry/p65 uses the specific mechanisms of both human decay-accelerating factor and membrane cofactor protein.	CR1 CR1L	5.36e-06	3	47	2	7528766
Pubmed	An allelic variant of Crry in the murine Sle1c lupus susceptibility interval is not impaired in its ability to regulate complement activation.	CR1 CR1L	5.36e-06	3	47	2	20660348
Pubmed	The EGF-like proteins DLK1 and DLK2 function as inhibitory non-canonical ligands of NOTCH1 receptor that modulate each other's activities.	DLK2 NOTCH1	5.36e-06	3	47	2	21419176
Pubmed	[Hepatitis B virus X protein upregulates the expression of CD59 and Crry in mouse podocytes].	CR1 CR1L	5.36e-06	3	47	2	21215189
Pubmed	The murine complement receptor gene family. IV. Alternative splicing of Cr2 gene transcripts predicts two distinct gene products that share homologous domains with both human CR2 and CR1.	CR1 CR1L	5.36e-06	3	47	2	2139460
Pubmed	A critical role for murine complement regulator crry in fetomaternal tolerance.	CR1 CR1L	5.36e-06	3	47	2	10642554
Pubmed	p21-activated kinase regulates mast cell degranulation via effects on calcium mobilization and cytoskeletal dynamics.	CR1 CR1L	1.07e-05	4	47	2	19124833
Pubmed	Distinct roles for the complement regulators factor H and Crry in protection of the kidney from injury.	CR1 CR1L	1.07e-05	4	47	2	27165610
Pubmed	Loss of CD11b exacerbates murine complement-mediated tubulointerstitial nephritis.	CR1 CR1L	1.07e-05	4	47	2	24632830
Pubmed	DAF/Crry double deficiency in mice exacerbates nephrotoxic serum-induced proteinuria despite markedly reduced systemic complement activity.	CR1 CR1L	1.07e-05	4	47	2	16887189
Pubmed	Membrane protein Crry maintains homeostasis of the complement system.	CR1 CR1L	1.07e-05	4	47	2	18684964
Pubmed	Targeted complement inhibition by C3d recognition ameliorates tissue injury without apparent increase in susceptibility to infection.	CR1 CR1L	1.07e-05	4	47	2	16127466
Pubmed	Complement C3-Targeted Gene Therapy Restricts Onset and Progression of Neurodegeneration in Chronic Mouse Glaucoma.	CR1 CR1L	1.07e-05	4	47	2	30217731
Pubmed	Complement-mediated clearance of erythrocytes: mechanism and delineation of the regulatory roles of Crry and DAF. Decay-accelerating factor.	CR1 CR1L	1.07e-05	4	47	2	12393518
Pubmed	Genetic and therapeutic targeting of properdin in mice prevents complement-mediated tissue injury.	CR1 CR1L	1.07e-05	4	47	2	20941861
Pubmed	Mouse CD4+ CD25+ T regulatory cells are protected from autologous complement mediated injury by Crry and CD59.	CR1 CR1L	1.07e-05	4	47	2	19281793
Pubmed	Complement receptor 1 gene variants are associated with erythrocyte sedimentation rate.	CR1 CR1L	1.78e-05	5	47	2	21700265
Pubmed	Complement modulation in the retinal pigment epithelium rescues photoreceptor degeneration in a mouse model of Stargardt disease.	CR1 CR1L	1.78e-05	5	47	2	28348233
Pubmed	Deletion of Crry and DAF on murine platelets stimulates thrombopoiesis and increases factor H-dependent resistance of peripheral platelets to complement attack.	CR1 CR1L	1.78e-05	5	47	2	23390291
Pubmed	C3-dependent mechanism of microglial priming relevant to multiple sclerosis.	CR1 CR1L	1.78e-05	5	47	2	22219359
Pubmed	Crry, but not CD59 and DAF, is indispensable for murine erythrocyte protection in vivo from spontaneous complement attack.	CR1 CR1L	1.78e-05	5	47	2	11986227
Pubmed	Activator-specific requirement of properdin in the initiation and amplification of the alternative pathway complement.	CR1 CR1L	1.78e-05	5	47	2	17916747
Pubmed	Retrovirus-mediated over-expression of decay-accelerating factor rescues Crry-deficient erythrocytes from acute alternative pathway complement attack.	CR1 CR1L	1.78e-05	5	47	2	17015743
Pubmed	The complement inhibitors Crry and factor H are critical for preventing autologous complement activation on renal tubular epithelial cells.	CR1 CR1L	1.78e-05	5	47	2	20675597
Pubmed	Targeted complement inhibitors protect against posttransplant cardiac ischemia and reperfusion injury and reveal an important role for the alternative pathway of complement activation.	CR1 CR1L	1.78e-05	5	47	2	20962256
Pubmed	Exploring genome-wide - dietary heme iron intake interactions and the risk of type 2 diabetes.	MUSK SVEP1	2.67e-05	6	47	2	23386860
Pubmed	Distinct roles for C3a and C5a in complement-induced tubulointerstitial injury.	CR1 CR1L	2.67e-05	6	47	2	21677637
Pubmed	Complement-dependent T-cell lymphopenia caused by thymocyte deletion of the membrane complement regulator Crry.	CR1 CR1L	2.67e-05	6	47	2	19136662
Pubmed	Absence of CD59 exacerbates systemic autoimmunity in MRL/lpr mice.	CR1 CR1L	2.67e-05	6	47	2	23109726
Pubmed	The regulation of the complement system: insights from genetically-engineered mice.	CR1 CR1L	3.74e-05	7	47	2	12914820
Pubmed	Murine systemic thrombophilia and hemolytic uremic syndrome from a factor H point mutation.	CR1 CR1L	3.74e-05	7	47	2	28057640
Pubmed	The retinoic acid receptor beta (Rarb) region of Mmu14 is associated with prion disease incubation time in mouse.	CR1 CR1L	3.74e-05	7	47	2	21151910
Pubmed	Genetic organization of complement receptor-related genes in the mouse.	CR1 CR1L	4.98e-05	8	47	2	2564419
Pubmed	Negligible role of antibodies and C5 in pregnancy loss associated exclusively with C3-dependent mechanisms through complement alternative pathway.	CR1 CR1L	4.98e-05	8	47	2	14670299
Pubmed	Crry deficiency in complement sufficient mice: C3 consumption occurs without associated renal injury.	CR1 CR1L	6.40e-05	9	47	2	18947875
Pubmed	Circulating AIM prevents hepatocellular carcinoma through complement activation.	CR1 CR1L	7.99e-05	10	47	2	25284781
Pubmed	Influence of the apoA-II gene locus on HDL levels and fatty streak development in mice.	CR1 CR1L	7.99e-05	10	47	2	8422330
Pubmed	Mapping of recombinant retrovirus integration sites that cause expression of the viral genome in murine embryonal carcinoma cells.	CR1 CR1L	9.75e-05	11	47	2	1543915
Pubmed	Combination of factor H mutation and properdin deficiency causes severe C3 glomerulonephritis.	CR1 CR1L	9.75e-05	11	47	2	23204401
Pubmed	Otogelin, otogelin-like, and stereocilin form links connecting outer hair cell stereocilia to each other and the tectorial membrane.	OTOGL OTOG	9.75e-05	11	47	2	31776257
Pubmed	Deficiency of decay-accelerating factor and complement receptor 1-related gene/protein y on murine platelets leads to complement-dependent clearance by the macrophage phagocytic receptor CRIg.	CR1 CR1L	1.17e-04	12	47	2	18524992
Pubmed	Several genes contribute to the production of autoreactive B and T cells in the murine lupus susceptibility locus Sle1c.	CR1 CR1L	1.38e-04	13	47	2	16002709
Pubmed	Multiple loci influencing hippocampal degeneration identified by genome scan.	SELP VPS13B	1.38e-04	13	47	2	22745009
Pubmed	Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition.	G2E3 RAB40A MUSK TRIM56 TRIM10	1.45e-04	372	47	5	22939624
Pubmed	Aurora B opposes PP1 function in mitosis by phosphorylating the conserved PP1-binding RVxF motif in PP1 regulatory proteins.	CEP192 PPA1	2.12e-04	16	47	2	29764992
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	CEP192 CSMD3 VPS13B PLXNB3 RHOBTB2	2.19e-04	407	47	5	12693553
Pubmed	An essential role for Polycomb Repressive Complex 2 in the mouse ovary.	EHMT1 IGFBP3 NOTCH1	3.21e-04	98	47	3	35084365
Pubmed	Transcriptome profiling of mouse brain and lung under Dip2a regulation using RNA-sequencing.	DLK2 PLXNB3	3.34e-04	20	47	2	31291246
Pubmed	Constitutive expression of TNF-alpha and -beta genes in mouse embryo: roles of cytokines as regulator and effector on development.	CR1 CR1L	3.69e-04	21	47	2	8138038
Pubmed	TRIM E3 ligases interfere with early and late stages of the retroviral life cycle.	TRIM56 TRIM10	3.69e-04	21	47	2	18248090
Pubmed	Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.	C1S FCGBP IGFBP3 APOH	4.05e-04	257	47	4	16335952
Pubmed	A proteomic analysis of human bile.	FCGBP APOH	4.06e-04	22	47	2	15084671
Pubmed	Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.	PPA1 RB1CC1 IGFBP3 CRIM1 TRIM47 FBXO46 NOTCH1	5.22e-04	1061	47	7	33845483
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	EHMT1 PHLDB3 CEP192 LARS2 FBXO46 NOTCH1 CASKIN1	6.65e-04	1105	47	7	35748872
Pubmed	Notch signaling in stomach epithelial stem cell homeostasis.	DLK2 NOTCH1	7.09e-04	29	47	2	21402740
Pubmed	PAK4 promotes kinase-independent stabilization of RhoU to modulate cell adhesion.	RAB40A LARS2 ZFAND2B	7.34e-04	130	47	3	26598620
Pubmed	Risk of non-Hodgkin lymphoma in association with germline variation in complement genes.	C1S CR1	8.11e-04	31	47	2	19344414
Pubmed	Genome-wide association study of lung function decline in adults with and without asthma.	MUSK SVEP1	8.64e-04	32	47	2	22424883
Pubmed	Interactome of vertebrate GAF/ThPOK reveals its diverse functions in gene regulation and DNA repair.	EHMT1 MPDZ MRPS25 TRIM56	9.29e-04	321	47	4	32098917
Cytoband	19q13.1	ITPKC FCGBP	1.47e-03	55	47	2	19q13.1
GeneFamily	Hyalectan proteoglycans\|V-set domain containing\|Sushi domain containing\|C-type lectin domain containing	SELP C1S APOH CR1 CR1L CSMD3 SVEP1	6.69e-12	57	32	7	1179
GeneFamily	Complement system\|Sushi domain containing	C1S CR1 CR1L	3.46e-05	36	32	3	492
GeneFamily	Zinc fingers AN1-type\|UPF1 like RNA helicases	ZFAND2A ZFAND2B	8.44e-05	8	32	2	63
GeneFamily	Ring finger proteins\|Tripartite motif containing\|ARF GTPase family	TRIM47 TRIM56 TRIM10	6.24e-04	95	32	3	59
GeneFamily	Armadillo repeat containing\|Protein phosphatase 1 regulatory subunits	MARF1 CEP192 RB1CC1	3.95e-03	181	32	3	694
GeneFamily	Ankyrin repeat domain containing	EHMT1 NOTCH1 CASKIN1	8.82e-03	242	32	3	403
GeneFamily	Ring finger proteins	TRIM47 TRIM56 TRIM10	1.25e-02	275	32	3	58
Coexpression	NABA_ECM_GLYCOPROTEINS	IGFBP3 CRIM1 SSPOP OTOGL SVEP1 OTOG	1.16e-06	191	47	6	MM17059
Coexpression	NABA_CORE_MATRISOME	IGFBP3 CRIM1 SSPOP OTOGL SVEP1 OTOG	8.52e-06	270	47	6	MM17057
Coexpression	LIM_MAMMARY_STEM_CELL_UP	DLK2 MPDZ ANTXR1 THSD1 IGFBP3 SVEP1 PLCH2	2.18e-05	479	47	7	M2573
Coexpression	LIM_MAMMARY_STEM_CELL_UP	DLK2 MPDZ ANTXR1 THSD1 IGFBP3 SVEP1 PLCH2	2.30e-05	483	47	7	MM1082
Coexpression	NABA_ECM_GLYCOPROTEINS	IGFBP3 CRIM1 SSPOP SVEP1 OTOG	2.64e-05	196	47	5	M3008
Coexpression	NABA_MATRISOME	IGFBP3 IL17D CRIM1 SSPOP OTOGL SVEP1 PLXNB3 GDF6 OTOG	6.48e-05	1008	47	9	MM17056
Coexpression	WARTERS_IR_RESPONSE_5GY	PHLDB3 THSD1 NOTCH1	9.98e-05	50	47	3	M2601
Coexpression	NABA_CORE_MATRISOME	IGFBP3 CRIM1 SSPOP SVEP1 OTOG	1.31e-04	275	47	5	M5884
Coexpression	GAO_LARGE_INTESTINE_ADULT_CG_GOBLET_CELL_SUBTYPE_2	MPDZ ANTXR1 C1S	1.48e-04	57	47	3	M39164
ToppCell	TCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_Diffuse-3\|TCGA-Stomach / Sample_Type by Project: Shred V9	SELP THSD1 CR1 MUSK SVEP1 GDF6	2.26e-08	167	47	6	d2230c894ccf9dbba9196e079ae81f384d43da63
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CSMD3 SSPOP OTOGL ASXL3 OTOG	1.45e-06	184	47	5	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CSMD3 SSPOP OTOGL ASXL3 OTOG	1.45e-06	184	47	5	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CSMD3 SSPOP OTOGL ASXL3 OTOG	1.45e-06	184	47	5	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	facs-Skin-Telogen-3m-Epithelial-Basal_IFE\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DLK2 ANTXR1 FCGBP IGFBP3 TRIM47	1.61e-06	188	47	5	8cc927b4c51d982fdafa04dc7393617ad9bb220e
ToppCell	facs-Skin-Skin_Anagen-18m-Epithelial-Basal_IFE\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DLK2 ANTXR1 ITPKC FCGBP TRIM47	1.65e-06	189	47	5	1cfc1fe27c4b57b4e52700fa8f679ce172cee5a9
ToppCell	facs-Skin-Anagen-3m-Epithelial-basal_cell_of_epidermis\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DLK2 ANTXR1 FCGBP TRIM47 LARS2	1.78e-06	192	47	5	ec1fd2fb6e71f87189d66261909a84e2be63cacb
ToppCell	facs-Heart-RV-3m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANTXR1 C1S IGFBP3 IL17D SVEP1	1.83e-06	193	47	5	735a72fac16397edde95e8eefa6f83caeb5ee5df
ToppCell	facs-Heart-RV-3m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANTXR1 C1S IGFBP3 IL17D SVEP1	1.83e-06	193	47	5	76f0f8569255d6cdf1e3b8e954cae72e71f87157
ToppCell	facs-Heart-RV-3m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANTXR1 C1S IGFBP3 IL17D SVEP1	1.83e-06	193	47	5	ff901d2f3d7a511639c1e3b76058896c0d8a8602
ToppCell	ILEUM-inflamed-(8)_Fibroblasts\|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	ANTXR1 C1S IGFBP3 MUSK SVEP1	2.12e-06	199	47	5	3a3e2bb21cd0293622b1a975263e918d9ba24265
ToppCell	droplet-Large_Intestine-COLON_-_"PROM_Tm"-30m-Epithelial-Lgr5+_undifferentiated_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SELP LARS2 ASXL3 NOTCH1	1.40e-05	139	47	4	c300f953ff9c5e820ff16bcd9942d279b37b79db
ToppCell	droplet-Large_Intestine-COLON_-_"PROM_Tm"-30m-Epithelial-intestinal_crypt_stem_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SELP LARS2 ASXL3 NOTCH1	1.40e-05	139	47	4	95b19d7459d9b54162cf01d278462245d34802d5
ToppCell	Adult-Epithelial-basal_cell-D122\|Adult / Lineage, Cell type, age group and donor	DLK2 ASXL3 PLCH2 CASKIN1	2.10e-05	154	47	4	38d346402417960044ae999e61f0092b46f2b591
ToppCell	PND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SELP G2E3 TRIM47 CASKIN1	2.15e-05	155	47	4	8e239470799426ea474a36f57e1b7e0d9365ca5f
ToppCell	390C-Lymphocytic-NK_cells-NK_cell_B0\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	DLK2 IGFBP3 CR1L TRIM10	2.75e-05	165	47	4	ebd668e87e5961a124d1d6fc25d1f03e4af05cd4
ToppCell	PND14-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SELP CRIM1 TRIM47 NOTCH1	2.82e-05	166	47	4	7a45785a40b7425f97be67bab1c5ceb69b2bd85a
ToppCell	PND14-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SELP CRIM1 TRIM47 NOTCH1	2.82e-05	166	47	4	bbd382812f8a84a5d99888de2d7cca3a8b5e4695
ToppCell	tumor_Lymph_Node_/_Brain-Fibroblasts-COL13A1+_matrix_FBs\|Fibroblasts / Location, Cell class and cell subclass	PHLDB3 C1S ITPKC SVEP1	3.02e-05	169	47	4	84b898a9fd8ced67c6a501d5cef6416f519902c4
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ANTXR1 C1S MUSK SVEP1	3.02e-05	169	47	4	c0824a93674e2bff0f09b2d2fab5bab016a2e379
ToppCell	5'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-mLTo\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	C1S IGFBP3 TRIM47 OTOGL	3.02e-05	169	47	4	559e98216720e4babf0b0941100f1b485c35b11b
ToppCell	3'-Child04-06-SmallIntestine-Mesenchymal-fibroblastic-mLTo\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ANTXR1 C1S IGFBP3 CR1L	3.09e-05	170	47	4	7653f1205d4e62abe7e31b1d76f9bbd665e45667
ToppCell	Nasal_Brush-Epithelial-Basal_2\|Nasal_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X	DLK2 C1S CSMD3 KRT32	3.54e-05	176	47	4	fc5787946f5a10056d326d070620575ae4081836
ToppCell	Nasal_Brush-Epithelial-Basal_2\|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X	DLK2 C1S CSMD3 KRT32	3.54e-05	176	47	4	5daaba0853afe7d20d4635169ccd4f96e735b938
ToppCell	Adult-Immune-enucleated_erythrocyte-D231\|Adult / Lineage, Cell type, age group and donor	ZFAND2A CR1L PLCH2 NOTCH1	3.62e-05	177	47	4	15ee303fb6caea1fd645c3b777666196ce500a1c
ToppCell	PND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SELP CRIM1 TRIM47 NOTCH1	3.95e-05	181	47	4	4d7793026373cbcf04b15c77f95f1025d07d4c00
ToppCell	facs-Skin-Anagen-3m-Epithelial-Basal_IFE\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DLK2 ANTXR1 FCGBP TRIM47	4.03e-05	182	47	4	22d6f4790950508e8aa27e02a8133af5f53f13c8
ToppCell	PND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SELP CRIM1 TRIM47 NOTCH1	4.12e-05	183	47	4	3427f3cbe6ea81709750e7dd3ff378f03ae65eab
ToppCell	Basal\|World / shred by cell class for mouse tongue	DLK2 ANTXR1 IGFBP3 CRIM1	4.12e-05	183	47	4	c6729a207526ff4aa48176207b9353176f631fea
ToppCell	3'-Distal_airway-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	C1S IL17D OTOGL SVEP1	4.12e-05	183	47	4	2beb5414958d38a5341870d55229f3b1707e76bf
ToppCell	facs-Trachea-18m-Epithelial-airway_epithelial-respiratory_basal_cell-basal_epithelial_cell_of_trachea\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DLK2 FCGBP LARS2 PLCH2	4.21e-05	184	47	4	45ff845ceed5960a997545c1009012b65e377d50
ToppCell	facs-Trachea-18m-Epithelial-airway_epithelial-respiratory_basal_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DLK2 FCGBP LARS2 PLCH2	4.21e-05	184	47	4	2cc2646dee3c6001f7c10b7449c17d1935021958
ToppCell	droplet-Skin\|droplet / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DLK2 PHLDB3 FCGBP KRT32	4.30e-05	185	47	4	657fd191ed160f8620d57b33820ec7222806f289
ToppCell	facs-Trachea-3m-Epithelial-airway_epithelial\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DLK2 FCGBP LARS2 PLCH2	4.39e-05	186	47	4	37b93ebd64ebbd08193a746e5bc9b350c2570733
ToppCell	Mesenchymal_cells-Adipo-CAR\|World / Lineage and Cell class	MPDZ ANTXR1 IGFBP3 SVEP1	4.39e-05	186	47	4	6ca8ce7ced91d6308b7c056032ffec1b37c974bf
ToppCell	facs-Skin-Telogen-3m-Epithelial-basal_cell_of_epidermis\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DLK2 ANTXR1 FCGBP TRIM47	4.48e-05	187	47	4	9c1013720c248ef201d010806b6e7ad24205e8ee
ToppCell	metastatic_Lymph_Node-Endothelial_cells-Tumor_ECs\|metastatic_Lymph_Node / Location, Cell class and cell subclass	SELP MPDZ CRIM1 ASXL3	4.48e-05	187	47	4	2713f526f86911fbbf6c7a3e69230f2e6bde31c3
ToppCell	metastatic_Lymph_Node-Fibroblasts-COL13A1+_matrix_FBs\|metastatic_Lymph_Node / Location, Cell class and cell subclass	MPDZ C1S MUSK SVEP1	4.48e-05	187	47	4	e04fb35f2f5b120659d06b5ae427ab1ec56d5c36
ToppCell	5'-Adult-Distal_Rectal-Endothelial-lymphatic_endothelial-LEC6_(ADAMTS4+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DLK2 THSD1 SSPOP NOTCH1	4.58e-05	188	47	4	524a12f433c7b6f33fad36c0716afa06cd3235e9
ToppCell	facs-Trachea-3m-Epithelial-airway_epithelial-respiratory_basal_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DLK2 FCGBP LARS2 PLCH2	4.58e-05	188	47	4	8ffb5394f7b00ea483a5fe4df894d22fda935e5c
ToppCell	facs-Trachea-3m-Epithelial-airway_epithelial-respiratory_basal_cell-basal_epithelial_cell_of_trachea\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DLK2 FCGBP LARS2 PLCH2	4.58e-05	188	47	4	137ed9958044fab7a13648affb469585d1c48cf6
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ANTXR1 C1S IGFBP3 SVEP1	4.58e-05	188	47	4	ce85a56ac27a6432421dde93a1bafa8b943244b9
ToppCell	P28-Endothelial-large_vessel_endothelial_cell\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	SELP CRIM1 TRIM47 NOTCH1	4.58e-05	188	47	4	263169029293e005bcffd87db20221fdd2d3917e
ToppCell	5'-Adult-Distal_Rectal-Endothelial-lymphatic_endothelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DLK2 THSD1 SSPOP NOTCH1	4.58e-05	188	47	4	d2610b81b3c7f22977b5e2137b1f61410fc4ef16
ToppCell	droplet-Heart-4Chambers-21m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANTXR1 C1S IGFBP3 IL17D	4.67e-05	189	47	4	2a5fda73d38bdc23cf47e5335ffd4e086e990245
ToppCell	facs-Trachea-24m-Epithelial-airway_epithelial-respiratory_basal_cell-basal_epithelial_cell_of_trachea\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DLK2 FCGBP LARS2 PLCH2	4.67e-05	189	47	4	ee15b4fb3a1cfda80bcf210a23f04f242594015e
ToppCell	facs-Trachea-24m-Epithelial-airway_epithelial-respiratory_basal_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DLK2 FCGBP LARS2 PLCH2	4.67e-05	189	47	4	dc6f6fae84347d145bea71b49eaeeb3028e9c4ae
ToppCell	droplet-Kidney-nan-3m-Mesenchymal-fibroblast\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANTXR1 C1S IL17D SVEP1	4.77e-05	190	47	4	f61e21d53f2f7804ac6e40ab6c7f69838aa94d6a
ToppCell	droplet-Kidney-nan-3m-Mesenchymal\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANTXR1 C1S IL17D SVEP1	4.77e-05	190	47	4	2abeb013bb83c578e67dcb985ba44ca63134950b
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ANTXR1 C1S IGFBP3 SVEP1	4.77e-05	190	47	4	efb757f11c2809e66ddb48a5c84f5433f111cb7c
ToppCell	Control-Endothelial-VE_Venous\|Endothelial / Disease state, Lineage and Cell class	SELP C1S ITPKC CRIM1	4.77e-05	190	47	4	4e30155203b4a8c5e496fcbe9348b67b98ebc625
ToppCell	droplet-Heart-4Chambers-21m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANTXR1 C1S IGFBP3 IL17D	4.87e-05	191	47	4	f892f725a32e704cd18fec2f6d1db82993e7e79a
ToppCell	droplet-Kidney-nan-3m-Mesenchymal-Stroma____fibroblast\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANTXR1 C1S IL17D SVEP1	4.87e-05	191	47	4	d1205aab0937f2becfcd239610e9b78fb8a0c886
ToppCell	droplet-Heart-4Chambers-21m-Mesenchymal-fibroblast\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANTXR1 C1S IGFBP3 IL17D	4.87e-05	191	47	4	44631226f59364098a7dd58058e6970a75441009
ToppCell	RV-01._Fibroblast_I\|RV / Chamber and Cluster_Paper	ANTXR1 C1S MUSK SVEP1	4.97e-05	192	47	4	356160b113c3305a61ceeaff33ce3c9da0be2878
ToppCell	3'-Adult-LargeIntestine-Mesenchymal-fibroblastic-mLN_Stroma_(FMO2+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	C1S IGFBP3 SVEP1 GDF6	4.97e-05	192	47	4	11867f30f0b420c18cb0b34d3990237aa737a0e8
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ANTXR1 C1S ASXL3 SVEP1	5.07e-05	193	47	4	fb28717fadd06c3840636d25409ce80c9254bd34
ToppCell	LV-01._Fibroblast_I\|LV / Chamber and Cluster_Paper	ANTXR1 C1S MUSK SVEP1	5.07e-05	193	47	4	dc17f3b9758936d428cf17f77a1ce6d4c479b165
ToppCell	droplet-Pancreas-Endocrine-21m-Mesenchymal\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANTXR1 C1S ASXL3 SVEP1	5.07e-05	193	47	4	03678162648bd5b1d65a5450b60c8863edbf95c7
ToppCell	droplet-Pancreas-Endocrine-21m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANTXR1 C1S ASXL3 SVEP1	5.07e-05	193	47	4	59b8186d0221fba06a16157e9d148399ed801f38
ToppCell	P15-Endothelial-large_vessel_endothelial_cell\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	SELP CRIM1 TRIM47 NOTCH1	5.07e-05	193	47	4	5f9a7cd5f8eb9ac294cdb50518fedf872f3f78f5
ToppCell	droplet-Pancreas-Endocrine-21m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANTXR1 C1S ASXL3 SVEP1	5.07e-05	193	47	4	dc92680b4bb9fc26430c92e03adb839c8c3b3b98
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_adventitial_fibro_(10)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	C1S IGFBP3 SVEP1 GDF6	5.07e-05	193	47	4	adc9fc94f9ec686a417d08c0b8b7b7ab687afec0
ToppCell	droplet-Fat-BAT+GAT+MAT-30m-Mesenchymal\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANTXR1 C1S IL17D SVEP1	5.17e-05	194	47	4	54a7f693966b5c02f6b248950ddb5fa32af3ae67
ToppCell	droplet-Fat-BAT+GAT+MAT-30m-Mesenchymal-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANTXR1 C1S IL17D SVEP1	5.17e-05	194	47	4	da926441053b499cb5107ccb116fb1b3844d82b7
ToppCell	TCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_NOS-3\|TCGA-Stomach / Sample_Type by Project: Shred V9	MPDZ ANTXR1 C1S SVEP1	5.17e-05	194	47	4	2260cd817a6661e5eb6645b0c6786e18fd58371e
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ANTXR1 C1S ASXL3 SVEP1	5.17e-05	194	47	4	89b706af2b25991fc2707eb24f49ba6ff3ae01f7
ToppCell	LV-02._Fibroblast_II\|LV / Chamber and Cluster_Paper	ANTXR1 C1S MUSK SVEP1	5.17e-05	194	47	4	014d2feb5db2a6a35ef759761a41e466e108c3c1
ToppCell	droplet-Fat-BAT+GAT+MAT-30m-Mesenchymal-mesenchymal_stem_cell_of_adipose\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANTXR1 C1S IL17D SVEP1	5.17e-05	194	47	4	f34b3bbdebf56f66ff499e390e5515a4a4093f90
ToppCell	facs-Trachea-24m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l1\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ANTXR1 C1S IL17D SVEP1	5.17e-05	194	47	4	889c6e231bdd5b59902c7d2afdc077360b1d3256
ToppCell	droplet-Heart-nan-18m-Mesenchymal-fibroblast\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANTXR1 C1S IGFBP3 IL17D	5.27e-05	195	47	4	9ffabd831c2a0de3597f328e83db7ee259cb0ccc
ToppCell	COVID-19-Heart-Fib_1\|Heart / Disease (COVID-19 only), tissue and cell type	C1S IGFBP3 MUSK SVEP1	5.27e-05	195	47	4	f423baa36ac7cdc383c033e35a7d17e6bf913323
ToppCell	droplet-Heart-nan-18m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANTXR1 C1S IGFBP3 IL17D	5.27e-05	195	47	4	613bea20c3d82c22a6af4c1a668af6fcf11fec0a
ToppCell	Substantia_nigra-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Rgs5_(Mural.Rgs5Acta2.Rgs5)-\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	C1S OTOGL TRIM10	5.33e-05	69	47	3	a157b1582401cebd222343d94086dbea876140c2
ToppCell	Substantia_nigra-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Rgs5_(Mural.Rgs5Acta2.Rgs5)\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	C1S OTOGL TRIM10	5.33e-05	69	47	3	cdd42abdd072aa438830d837ee857529269a81e0
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_2_cell-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	C1S IGFBP3 SVEP1 GDF6	5.38e-05	196	47	4	525d6c8a277364e624e7cc586275f8a891436b57
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ANTXR1 C1S IGFBP3 CSMD3	5.38e-05	196	47	4	85507488f83d8f71b3ee2ad5e5aa0b6ad6193873
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(CCL11+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ANTXR1 C1S MUSK SVEP1	5.38e-05	196	47	4	2ab9735aa7a7e95dcf6b0bdf0427f7b57f6349ee
ToppCell	nucseq-Mesenchymal-Fibroblastic\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ANTXR1 C1S MUSK SVEP1	5.38e-05	196	47	4	7d8505dac15fa59935ccf592afc54b04c4c6554f
ToppCell	COPD-Stromal-Myofibroblast\|World / Disease state, Lineage and Cell class	ANTXR1 C1S MUSK SVEP1	5.49e-05	197	47	4	d51f484b4e01ac64233950d0b97fa88825ea1dbb
ToppCell	droplet-Trachea-nan-3m-Mesenchymal-chondrocyte\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PPA1 IL17D CRIM1 TRIM47	5.49e-05	197	47	4	8786125b669d5d0b15e12df0ade6b319f09f7333
ToppCell	5'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ANTXR1 C1S IGFBP3 CSMD3	5.49e-05	197	47	4	236a40eb6c08e1d179cf0fb5450b032975c5f6b6
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_airway_basal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DLK2 IGFBP3 ASXL3 PLCH2	5.49e-05	197	47	4	107cb153ea7fc74bbd244dbb9d0499c0a8506724
ToppCell	Parenchymal-10x5prime-Epithelial-Epi_airway_basal-Suprabasal\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	DLK2 IGFBP3 ASXL3 PLCH2	5.60e-05	198	47	4	de5987588b9fa9ee8c595ba06d7d844ead0e3c74
ToppCell	5'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ANTXR1 C1S IGFBP3 CSMD3	5.60e-05	198	47	4	09be07ebfc3e49c3858e9b74605b69cf4fc28b56
ToppCell	3'-GW_trimst-2-SmallIntestine-Mesenchymal-immature_mesenchymal_cell\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	C1S MUSK SVEP1 GDF6	5.60e-05	198	47	4	bba40ece261741fa8c0e28de768af001d28f04f8
ToppCell	nucseq-Mesenchymal\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ANTXR1 C1S MUSK SVEP1	5.60e-05	198	47	4	8f52243ca8b9ba68a75ae411506a3a6de258eb97
ToppCell	droplet-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l34\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PPA1 IL17D CRIM1 TRIM47	5.60e-05	198	47	4	3575620db5aeaeb0bdcd7a8ff65c43abd3fa13e4
ToppCell	Bronchial-10x5prime-Stromal-Fibroblastic-Fibro_peribronchial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	ANTXR1 C1S MUSK SVEP1	5.71e-05	199	47	4	e1f1950d6f840485e263b83dc81b98910be3ae7a
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-immature_mesenchymal_cell-Mesoderm_2_(ZEB2+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	C1S MUSK SVEP1 GDF6	5.71e-05	199	47	4	da016849b804fbf80edbfa8f8f56c9df8bbf2d51
ToppCell	Bronchial-10x5prime-Stromal-Fibroblastic-Fibro_immune_recruiting\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	C1S IGFBP3 MUSK SVEP1	5.71e-05	199	47	4	0cdbedf09ec72734b86ddab3fec562e066afed92
ToppCell	10x5'v1-week_14-16-Mesenchymal_adipo-stroma\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	ANTXR1 C1S IGFBP3 SVEP1	5.71e-05	199	47	4	9b2262edbdec89166d895ab97527e0ee5f9b6010
ToppCell	medial-mesenchymal-Myofibroblast\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	C1S IL17D RAB40A ASXL3	5.71e-05	199	47	4	e25acdb5809aaff631cb06dbe4c7e59549a0bdb9
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-immature_mesenchymal_cell\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	C1S MUSK SVEP1 GDF6	5.71e-05	199	47	4	3cf62666ffd000427fdbb7cf940793f98c3ed29c
ToppCell	medial-2-mesenchymal-Myofibroblast\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	C1S IL17D RAB40A ASXL3	5.71e-05	199	47	4	95aae608fa35a9c82b12c6f18937ce636750ca44
ToppCell	10x5'v1-week_14-16-Mesenchymal_adipo\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	ANTXR1 C1S IGFBP3 SVEP1	5.71e-05	199	47	4	251b3643dcd8f4645b17101bd716e66f12a20e88
ToppCell	10x5'v1-week_14-16-Mesenchymal_adipo-stroma-adipo-CAR\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	ANTXR1 C1S IGFBP3 SVEP1	5.71e-05	199	47	4	117f4f43b6c06dda553799b1063e827bce697370
ToppCell	medial-mesenchymal-Myofibroblast-2\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	C1S IL17D RAB40A ASXL3	5.71e-05	199	47	4	9ebf4822ff9fa08574edec5dbf4f2a1488f34b1d
ToppCell	Bronchial_Brush-Epithelial-Basal_2\|Bronchial_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X	DLK2 PPA1 IGFBP3 NOTCH1	5.82e-05	200	47	4	1fa29a9f42987549a75dffeb177099458f7cca88
ToppCell	(5)_Epithelial_cells-(5)_Epi_suprabasal\|(5)_Epithelial_cells / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)	DLK2 C1S TRIM47 KRT32	5.82e-05	200	47	4	92382ca82da3e435ccbee1c73261d55164d54779
Disease	partial thromboplastin time	SELP C1S APOH	7.49e-06	24	47	3	EFO_0004310
Disease	dietary heme iron intake measurement, type 2 diabetes mellitus	MUSK SVEP1	3.71e-05	6	47	2	EFO_0008355, MONDO_0005148
Disease	blood sedimentation	CR1 CR1L	5.19e-05	7	47	2	EFO_0004304
Disease	quality of life during menstruation measurement, dysmenorrheic pain measurement	RB1CC1 VPS13B	1.35e-04	11	47	2	EFO_0007889, EFO_0009366
Disease	microphthalmia (implicated_via_orthology)	CRIM1 GDF6	1.62e-04	12	47	2	DOID:10629 (implicated_via_orthology)
Disease	response to paliperidone, schizophrenia symptom severity measurement	IFTAP CR1 CR1L CSMD3	3.89e-04	216	47	4	EFO_0007925, EFO_0007927
Disease	coagulation factor V measurement	SELP MUSK	4.63e-04	20	47	2	EFO_0008087
Disease	arteriosclerosis (is_marker_for)	IGFBP3 APOH	9.81e-04	29	47	2	DOID:2349 (is_marker_for)
Disease	triacylglycerol 58:10 measurement	MPDZ MUSK	1.35e-03	34	47	2	EFO_0010437

Protein segments in the cluster

Peptide	Gene	Start	Entry
VCAPIICPPPSIPTF	APOH	136	P02749
CCTVIIKEVPPPPAE	ANTXR1	346	Q9H6X2
PTCRAVTCPTPPQIS	CSMD3	3226	Q7Z407
PCIAIIPKCIESTPI	ASXL3	1291	Q9C0F0
VEIVCPPQSPPKNCT	RAB40A	256	Q8WXH6
CSPLCPVPRLIITPE	ITPKC	321	Q96DU7
PPPLTVQDPLCPAVC	RB1CC1	671	Q8TDY2
TPPPLVPECDVEVQP	PHLDB3	11	Q6NSJ2
VPTAVPTLCLPPEAD	CASKIN1	856	Q8WXD9
PPPLIEEACELPECQ	NOTCH1	1441	P46531
VPSPCVPRTVCVPRT	KRT32	421	Q14532
PCPILEPVCPEAIVC	PLXNB3	966	Q9ULL4
ETVCLTVSPEEPPPP	FBXO46	391	Q6PJ61
VTIPVGCTCVPEPEK	IL17D	161	Q8TAD2
SLPCTICLEFIEPIP	G2E3	141	Q7L622
IPSCIPFVAQPPTCE	IFTAP	136	Q86VG3
APICEIISCEPPPTI	CR1	1511	P17927
VPVCEQIFCPNPPAI	CR1	1766	P17927
PAPLTTPAVCEGPCV	FCGBP	3171	Q9Y6R7
ELPSCSRVCQPPPDV	CR1L	281	Q2VPA4
PVCERKSCETPPVPV	CR1L	406	Q2VPA4
PELPKCVPVCGVPRE	C1S	416	P09871
RTVECPPVQQTACPP	CRIM1	256	Q9NZV1
CEEPTIITVDPPACG	CRIM1	456	Q9NZV1
TVSCPPLPCVEPINV	CRIM1	851	Q9NZV1
PVDLLCAPVPSCLPS	MARF1	1621	Q9Y4F3
CISAAVPVPPCPSSE	MARF1	1691	Q9Y4F3
VPPECQAIPCTPLLS	SELP	501	P16109
LPPPCESACTVPTDV	PPA1	266	Q15181
PPCEQELSPLVCSPA	CEP192	1021	Q8TEP8
TCELVLPVPDPPTTV	DLK2	246	Q6UY11
IPIPCVNAVDSEPCP	EHMT1	1021	Q9H9B1
PVTCPLVPIPSCETP	MTBP	786	Q96DY7
CVYPRDCIPVIPTEP	OTOGL	1421	Q3ZCN5
PRVEGCVPVCPTPQV	OTOG	1436	Q6ZRI0
CAPPPAVCAELVREP	IGFBP3	51	P17936
PPSCCVPTKLTPISI	GDF6	416	Q6KF10
CEVEGQVPCPSLVPL	MRPS25	141	P82663
PFSCPICLEPLREPV	TRIM47	6	Q96LD4
DATQEEPCSPPVCPV	SSPOP	2816	A2VEC9
IVHCPVCGPTPVPLE	LARS2	461	Q15031
VCGPTPVPLEDLPVT	LARS2	466	Q15031
PIIVVPDPPSSSEEC	RHOBTB2	241	Q9BYZ6
DSFPVCKIVLCTPPP	SVEP1	2371	Q4LDE5
PICIPVDCSSPPVSA	SVEP1	2826	Q4LDE5
DVHVPVCPLCNTPIP	ZFAND2A	51	Q8N6M9
DPATCPIIPGCETTI	MPDZ	1616	O75970
PLPPLCSLETIAEEP	PLCH2	996	O75038
TCESGVEVTVLPPPC	THSD1	251	Q9NS62
IPGPDLEESPTCPLC	TRIM10	46	Q9UDY6
IPCPVVAAEPPPSTV	VPS13B	3976	Q7Z7G8
DIQVPVCPLCNVPVP	ZFAND2B	51	Q8WV99
CPECRETVPVPPEGV	TRIM56	56	Q9BRZ2
ECSPGVVPTPIPICR	MUSK	381	O15146