Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	benzodiazepine receptor binding	RIMBP3 RIMBP3C RIMBP3B	4.54e-06	5	155	3	GO:0030156
GeneOntologyBiologicalProcess	dendrite arborization	CHRNA7 SEMA3A CNTNAP2 CHRFAM7A	4.24e-06	15	158	4	GO:0140059
GeneOntologyCellularComponent	spine apparatus membrane	CHRNA7 CHRFAM7A	1.74e-04	3	160	2	GO:0098897
GeneOntologyCellularComponent	autolysosome membrane	HLA-DRB1 HLA-DRB3	3.46e-04	4	160	2	GO:0120281
GeneOntologyCellularComponent	basement membrane	NID2 HSPG2 COL7A1 LAMA5 EGFL6 HMCN2	3.56e-04	122	160	6	GO:0005604
MousePheno	ectopic manchette	CFAP65 RIMBP3 RIMBP3C RIMBP3B	1.81e-05	19	120	4	MP:0009377
MousePheno	detached sperm flagellum	CFAP65 RIMBP3 RIMBP3C RIMBP3B	2.76e-05	21	120	4	MP:0008893
MousePheno	airway basal cell hyperplasia	CHRNA7 CHRFAM7A	7.31e-05	2	120	2	MP:0011115
MousePheno	abnormal airway basal cell differentiation	CHRNA7 CHRFAM7A	7.31e-05	2	120	2	MP:0011114
MousePheno	abnormal airway basal cell morphology	CHRNA7 CHRFAM7A	7.31e-05	2	120	2	MP:0011113
Domain	EGF-like_dom	NID2 HSPG2 STAB2 FAT3 LAMA5 CUBN EGFL6 FCGBP HMCN2 CNTNAP2 TENM1	7.58e-06	249	155	11	IPR000742
Domain	EGF	NID2 HSPG2 STAB2 FAT3 LAMA5 CUBN EGFL6 FCGBP CNTNAP2 TENM1	2.74e-05	235	155	10	SM00181
Domain	EGF-like_CS	NID2 HSPG2 STAB2 FAT3 LAMA5 CUBN EGFL6 HMCN2 CNTNAP2 TENM1	6.64e-05	261	155	10	IPR013032
Domain	EGF_CA	NID2 HSPG2 STAB2 FAT3 CUBN EGFL6 HMCN2	7.14e-05	122	155	7	SM00179
Domain	EGF_2	NID2 HSPG2 STAB2 FAT3 LAMA5 CUBN EGFL6 HMCN2 CNTNAP2 TENM1	7.54e-05	265	155	10	PS01186
Domain	EGF-like_Ca-bd_dom	NID2 HSPG2 STAB2 FAT3 CUBN EGFL6 HMCN2	7.91e-05	124	155	7	IPR001881
Domain	GFP-like	NID2 STAB2 EGFL6	8.81e-05	11	155	3	IPR023413
Domain	-	NID2 STAB2 EGFL6	8.81e-05	11	155	3	2.40.155.10
Domain	ConA-like_dom	HSPG2 MID2 FAT3 LAMA5 RYR1 RYR2 EGFL6 CNTNAP2 BTNL9	9.10e-05	219	155	9	IPR013320
Domain	EGF_dom	NID2 STAB2 CUBN	1.17e-04	12	155	3	IPR024731
Domain	EGF_3	NID2 STAB2 CUBN	1.17e-04	12	155	3	PF12947
Domain	EGF_3	NID2 HSPG2 STAB2 FAT3 CUBN EGFL6 HMCN2 CNTNAP2 TENM1	1.55e-04	235	155	9	PS50026
Domain	Ryanodine_rcpt	RYR1 RYR2	2.04e-04	3	155	2	IPR003032
Domain	Ryanrecept_TM4-6	RYR1 RYR2	2.04e-04	3	155	2	IPR009460
Domain	RyR	RYR1 RYR2	2.04e-04	3	155	2	PF02026
Domain	RR_TM4-6	RYR1 RYR2	2.04e-04	3	155	2	PF06459
Domain	Ryan_recept	RYR1 RYR2	2.04e-04	3	155	2	IPR013333
Domain	FN3	COL7A1 PRTG MYOM1 MID2 RIMBP3 LRRN3 RIMBP3C RIMBP3B	2.61e-04	199	155	8	PS50853
Domain	Ig-like_fold	HSPG2 COL7A1 PRTG MYOM1 MID2 HLA-DRB1 HLA-DRB3 RIMBP3 SEMA3A LRRN3 HMCN2 FCGR2A RIMBP3C RIMBP3B BTNL9 PLXNA2	2.64e-04	706	155	16	IPR013783
Domain	LAM_G_DOMAIN	HSPG2 FAT3 LAMA5 CNTNAP2	2.70e-04	38	155	4	PS50025
Domain	EGF_1	HSPG2 STAB2 FAT3 LAMA5 CUBN EGFL6 HMCN2 CNTNAP2 TENM1	2.85e-04	255	155	9	PS00022
Domain	Growth_fac_rcpt_	NID2 HSPG2 STAB2 LAMA5 CUBN EGFL6 HMCN2	3.28e-04	156	155	7	IPR009030
Domain	Laminin_G_2	HSPG2 FAT3 LAMA5 CNTNAP2	3.30e-04	40	155	4	PF02210
Domain	FN3_dom	COL7A1 PRTG MYOM1 MID2 RIMBP3 LRRN3 RIMBP3C RIMBP3B	3.63e-04	209	155	8	IPR003961
Domain	G2F	NID2 HMCN2	4.06e-04	4	155	2	PF07474
Domain	4_1_CTD	EPB41L1 EPB41L2	4.06e-04	4	155	2	PF05902
Domain	SAB	EPB41L1 EPB41L2	4.06e-04	4	155	2	PF04382
Domain	NIDOGEN_G2	NID2 HMCN2	4.06e-04	4	155	2	PS50993
Domain	GFP	NID2 HMCN2	4.06e-04	4	155	2	IPR009017
Domain	Argonaute_N	AGO1 AGO4	4.06e-04	4	155	2	IPR032474
Domain	Argonaute_Mid_dom	AGO1 AGO4	4.06e-04	4	155	2	IPR032473
Domain	ArgoL2	AGO1 AGO4	4.06e-04	4	155	2	IPR032472
Domain	Band_4.1_C	EPB41L1 EPB41L2	4.06e-04	4	155	2	IPR008379
Domain	SAB_dom	EPB41L1 EPB41L2	4.06e-04	4	155	2	IPR007477
Domain	G2_nidogen/fibulin_G2F	NID2 HMCN2	4.06e-04	4	155	2	IPR006605
Domain	ArgoN	AGO1 AGO4	4.06e-04	4	155	2	PF16486
Domain	ArgoMid	AGO1 AGO4	4.06e-04	4	155	2	PF16487
Domain	ArgoL2	AGO1 AGO4	4.06e-04	4	155	2	PF16488
Domain	-	HSPG2 COL7A1 PRTG MYOM1 MID2 HLA-DRB1 HLA-DRB3 RIMBP3 SEMA3A LRRN3 FCGR2A RIMBP3C RIMBP3B BTNL9 PLXNA2	4.21e-04	663	155	15	2.60.40.10
Domain	-	WDR4 COP1 BBS2 SEMA3A WDR74 KCTD3 SNRNP40 TAF5L DCAF11 PLXNA2	4.75e-04	333	155	10	2.130.10.10
Domain	LamG	HSPG2 FAT3 LAMA5 CNTNAP2	4.78e-04	44	155	4	SM00282
Domain	WD40/YVTN_repeat-like_dom	WDR4 COP1 BBS2 SEMA3A WDR74 KCTD3 SNRNP40 TAF5L DCAF11 PLXNA2	4.98e-04	335	155	10	IPR015943
Domain	PUG	UBXN6 ERN2	6.73e-04	5	155	2	SM00580
Domain	YD	NID2 TENM1	6.73e-04	5	155	2	IPR006530
Domain	DUF1785	AGO1 AGO4	6.73e-04	5	155	2	SM01163
Domain	EGF_CA	NID2 FAT3 CUBN EGFL6 HMCN2	7.48e-04	86	155	5	PF07645
Domain	WD40_repeat_dom	WDR4 COP1 BBS2 GTF3C4 WDR74 KCTD3 SNRNP40 TAF5L DCAF11	8.55e-04	297	155	9	IPR017986
Domain	FN3	COL7A1 PRTG MYOM1 MID2 LRRN3 RIMBP3C RIMBP3B	9.06e-04	185	155	7	SM00060
Domain	PQQ	AASDH ERN2	1.00e-03	6	155	2	SM00564
Domain	RIH_assoc-dom	RYR1 RYR2	1.00e-03	6	155	2	IPR013662
Domain	ADEAMc	ADAR ADARB2	1.00e-03	6	155	2	SM00552
Domain	A_deamin	ADAR ADARB2	1.00e-03	6	155	2	PF02137
Domain	A_DEAMIN_EDITASE	ADAR ADARB2	1.00e-03	6	155	2	PS50141
Domain	PUB_domain	UBXN6 ERN2	1.00e-03	6	155	2	IPR018997
Domain	PQQ_repeat	AASDH ERN2	1.00e-03	6	155	2	IPR002372
Domain	Ins145_P3_rec	RYR1 RYR2	1.00e-03	6	155	2	PF08709
Domain	RIH_assoc	RYR1 RYR2	1.00e-03	6	155	2	PF08454
Domain	ArgoL1	AGO1 AGO4	1.00e-03	6	155	2	PF08699
Domain	RIH_dom	RYR1 RYR2	1.00e-03	6	155	2	IPR000699
Domain	Ins145_P3_rcpt	RYR1 RYR2	1.00e-03	6	155	2	IPR014821
Domain	Ryanodine_recept-rel	RYR1 RYR2	1.00e-03	6	155	2	IPR015925
Domain	ArgoL1	AGO1 AGO4	1.00e-03	6	155	2	IPR014811
Domain	PQQ_beta_propeller_repeat	AASDH ERN2	1.00e-03	6	155	2	IPR018391
Domain	-	AASDH ERN2	1.00e-03	6	155	2	2.140.10.10
Domain	Quinoprotein_ADH-like_fam	AASDH ERN2	1.00e-03	6	155	2	IPR027295
Domain	-	RYR1 RYR2	1.00e-03	6	155	2	1.25.10.30
Domain	RYDR_ITPR	RYR1 RYR2	1.00e-03	6	155	2	PF01365
Domain	A_deamin	ADAR ADARB2	1.00e-03	6	155	2	IPR002466
Domain	EGF_Ca-bd_CS	NID2 FAT3 CUBN EGFL6 HMCN2	1.29e-03	97	155	5	IPR018097
Domain	Laminin_G	HSPG2 FAT3 LAMA5 CNTNAP2	1.37e-03	58	155	4	IPR001791
Domain	EGF_CA	NID2 FAT3 CUBN EGFL6 HMCN2	1.41e-03	99	155	5	PS01187
Domain	ASX_HYDROXYL	NID2 FAT3 CUBN EGFL6 HMCN2	1.47e-03	100	155	5	PS00010
Domain	PIWI	AGO1 AGO4	1.85e-03	8	155	2	PS50822
Domain	Piwi	AGO1 AGO4	1.85e-03	8	155	2	SM00950
Domain	Piwi	AGO1 AGO4	1.85e-03	8	155	2	PF02171
Domain	MHC_II_b_N	HLA-DRB1 HLA-DRB3	1.85e-03	8	155	2	PD000328
Domain	LAMININ_IVA	HSPG2 LAMA5	1.85e-03	8	155	2	PS51115
Domain	Laminin_B	HSPG2 LAMA5	1.85e-03	8	155	2	PF00052
Domain	Piwi	AGO1 AGO4	1.85e-03	8	155	2	IPR003165
Domain	LamB	HSPG2 LAMA5	1.85e-03	8	155	2	SM00281
Domain	Laminin_IV	HSPG2 LAMA5	1.85e-03	8	155	2	IPR000034
Domain	EGF-type_Asp/Asn_hydroxyl_site	NID2 FAT3 CUBN EGFL6 HMCN2	1.91e-03	106	155	5	IPR000152
Domain	EGF_LAM_2	HSPG2 STAB2 LAMA5	1.93e-03	30	155	3	PS50027
Domain	EGF_LAM_1	HSPG2 STAB2 LAMA5	1.93e-03	30	155	3	PS01248
Domain	PAZ	AGO1 AGO4	2.37e-03	9	155	2	PS50821
Domain	MHC_II_b_N	HLA-DRB1 HLA-DRB3	2.37e-03	9	155	2	IPR000353
Domain	Hydrolase_4	ABHD17A ABHD17C	2.37e-03	9	155	2	IPR022742
Domain	PAZ	AGO1 AGO4	2.37e-03	9	155	2	SM00949
Domain	MHC_II_beta	HLA-DRB1 HLA-DRB3	2.37e-03	9	155	2	SM00921
Domain	Hydrolase_4	ABHD17A ABHD17C	2.37e-03	9	155	2	PF12146
Domain	PAZ	AGO1 AGO4	2.37e-03	9	155	2	PF02170
Domain	MHC_II_beta	HLA-DRB1 HLA-DRB3	2.37e-03	9	155	2	PF00969
Domain	PAZ_dom	AGO1 AGO4	2.37e-03	9	155	2	IPR003100
Domain	MIR	RYR1 RYR2	2.95e-03	10	155	2	PF02815
Domain	MIR_motif	RYR1 RYR2	2.95e-03	10	155	2	IPR016093
Domain	MIR	RYR1 RYR2	2.95e-03	10	155	2	PS50919
Domain	MIR	RYR1 RYR2	2.95e-03	10	155	2	SM00472
Domain	EGF_Lam	HSPG2 STAB2 LAMA5	3.02e-03	35	155	3	SM00180
Domain	-	ABHD17A ACOT1 ABHD17C FAP EPHX4	3.16e-03	119	155	5	3.40.50.1820
Domain	AB_hydrolase	ABHD17A ACOT1 ABHD17C FAP EPHX4	3.16e-03	119	155	5	IPR029058
Pubmed	Basement membrane assembly of the integrin α8β1 ligand nephronectin requires Fraser syndrome-associated proteins.	NID2 HSPG2 COL7A1 LAMA5 EGFL6	2.24e-07	29	162	5	22613833
Pubmed	RIM-BP3 is a manchette-associated protein essential for spermiogenesis.	RIMBP3 RIMBP3C RIMBP3B	3.95e-07	4	162	3	19091768
Pubmed	Structure and evolution of RIM-BP genes: identification of a novel family member.	RIMBP3 RIMBP3C RIMBP3B	9.85e-07	5	162	3	17855024
Pubmed	Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.	NID2 HSPG2 COL7A1 CELA2A LAMA5 HMCN2 PLXNA2	1.92e-05	175	162	7	28071719
Pubmed	Enhancing cognitive function in chronic TBI: The Role of α7 nicotinic acetylcholine receptor modulation.	CHRNA7 CHRFAM7A	2.16e-05	2	162	2	38070724
Pubmed	Genetic deletion of α7 nicotinic acetylcholine receptors induces an age-dependent Alzheimer's disease-like pathology.	CHRNA7 CHRFAM7A	2.16e-05	2	162	2	34453977
Pubmed	Inhibition of pancreatic acinar mitochondrial thiamin pyrophosphate uptake by the cigarette smoke component 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone.	CHRNA7 CHRFAM7A	2.16e-05	2	162	2	26999808
Pubmed	Positive allosteric modulators of α7 nicotinic acetylcholine receptors affect neither the function of other ligand- and voltage-gated ion channels and acetylcholinesterase, nor β-amyloid content.	CHRNA7 CHRFAM7A	2.16e-05	2	162	2	27129924
Pubmed	Laminin 5 binds the NC-1 domain of type VII collagen.	COL7A1 LAMA5	2.16e-05	2	162	2	9245798
Pubmed	Sensorimotor gating and spatial learning in α7-nicotinic receptor knockout mice.	CHRNA7 CHRFAM7A	2.16e-05	2	162	2	23521765
Pubmed	Effect of α7 nicotinic acetylcholine receptor activation on cardiac fibroblasts: a mechanism underlying RV fibrosis associated with cigarette smoke exposure.	CHRNA7 CHRFAM7A	2.16e-05	2	162	2	28258105
Pubmed	The cholinergic anti-inflammatory system limits T cell infiltration into the neurodegenerative CNS, but cannot counteract complex CNS inflammation.	CHRNA7 CHRFAM7A	2.16e-05	2	162	2	19344760
Pubmed	Bidirectional Regulation of Aggression in Mice by Hippocampal Alpha-7 Nicotinic Acetylcholine Receptors.	CHRNA7 CHRFAM7A	2.16e-05	2	162	2	29114104
Pubmed	Paediatric celiac patients carrying the HLA-DR7-DQ2 and HLA-DR3-DQ2 haplotypes display small clinical differences.	HLA-DRB1 HLA-DRB3	2.16e-05	2	162	2	24628273
Pubmed	Autophagy is Involved in Neuroprotective Effect of Alpha7 Nicotinic Acetylcholine Receptor on Ischemic Stroke.	CHRNA7 CHRFAM7A	2.16e-05	2	162	2	33995108
Pubmed	E-cigarette-induced pulmonary inflammation and dysregulated repair are mediated by nAChR α7 receptor: role of nAChR α7 in SARS-CoV-2 Covid-19 ACE2 receptor regulation.	CHRNA7 CHRFAM7A	2.16e-05	2	162	2	32552811
Pubmed	Reduced CHRNA7 expression in C3H mice is associated with increases in hippocampal parvalbumin and glutamate decarboxylase-67 (GAD67) as well as altered levels of GABA(A) receptor subunits.	CHRNA7 CHRFAM7A	2.16e-05	2	162	2	24836856
Pubmed	Studies of sperm from mutant mice suggesting that two neurotransmitter receptors are important to the zona pellucida-initiated acrosome reaction.	CHRNA7 CHRFAM7A	2.16e-05	2	162	2	15948184
Pubmed	Alpha7 nicotinic acetylcholine receptor mediates chronic nicotine inhalation-induced cardiopulmonary dysfunction.	CHRNA7 CHRFAM7A	2.16e-05	2	162	2	35678315
Pubmed	The Importance of AGO 1 and 4 in Post-Transcriptional Gene Regulatory Function of tRF5-GluCTC, an Respiratory Syncytial Virus-Induced tRNA-Derived RNA Fragment.	AGO1 AGO4	2.16e-05	2	162	2	33233493
Pubmed	Functional role of alpha7 nicotinic receptor in physiological control of cutaneous homeostasis.	CHRNA7 CHRFAM7A	2.16e-05	2	162	2	12628457
Pubmed	An Mll4/COMPASS-Lsd1 epigenetic axis governs enhancer function and pluripotency transition in embryonic stem cells.	KMT2D KDM1A	2.16e-05	2	162	2	29404406
Pubmed	Activation of α-7 nicotinic acetylcholine receptor reduces ischemic stroke injury through reduction of pro-inflammatory macrophages and oxidative stress.	CHRNA7 CHRFAM7A	2.16e-05	2	162	2	25157794
Pubmed	Homeobox C8 inhibited the osteo-/dentinogenic differentiation and migration ability of stem cells of the apical papilla via activating KDM1A.	HOXC8 KDM1A	2.16e-05	2	162	2	32246725
Pubmed	Mesenchymal Stem Cells or Interleukin-6 Improve Episodic Memory of Mice Lacking α7 Nicotinic Acetylcholine Receptors.	CHRNA7 CHRFAM7A	2.16e-05	2	162	2	31202708
Pubmed	Prenatal nicotine exposure alters lung function and airway geometry through α7 nicotinic receptors.	CHRNA7 CHRFAM7A	2.16e-05	2	162	2	22246862
Pubmed	Activation of Nicotinic Acetylcholine Receptors Decreases Apoptosis in Human and Female Murine Pancreatic Islets.	CHRNA7 CHRFAM7A	2.16e-05	2	162	2	27471776
Pubmed	Targeting α-7 nicotinic acetylcholine receptor in the enteric nervous system: a cholinergic agonist prevents gut barrier failure after severe burn injury.	CHRNA7 CHRFAM7A	2.16e-05	2	162	2	22688057
Pubmed	Different Effects of Nicotine and N-Stearoyl-ethanolamine on Episodic Memory and Brain Mitochondria of α7 Nicotinic Acetylcholine Receptor Knockout Mice.	CHRNA7 CHRFAM7A	2.16e-05	2	162	2	32028688
Pubmed	Mutations and selection in the generation of class II histocompatibility antigen polymorphism.	HLA-DRB1 HLA-DRB3	2.16e-05	2	162	2	6589154
Pubmed	Activation of α7 Nicotinic Acetylcholine Receptor Ameliorates Zymosan-Induced Acute Kidney Injury in BALB/c Mice.	CHRNA7 CHRFAM7A	2.16e-05	2	162	2	30429582
Pubmed	A transgenic mouse model reveals fast nicotinic transmission in hippocampal pyramidal neurons.	CHRNA7 CHRFAM7A	2.16e-05	2	162	2	21501254
Pubmed	Cardiopulmonary arrest and resuscitation disrupts cholinergic anti-inflammatory processes: a role for cholinergic α7 nicotinic receptors.	CHRNA7 CHRFAM7A	2.16e-05	2	162	2	21368056
Pubmed	Expression of human apolipoprotein A-II and its effect on high density lipoproteins in transgenic mice.	CHRNA7 CHRFAM7A	2.16e-05	2	162	2	1400473
Pubmed	Disease-associated bias in T helper type 1 (Th1)/Th2 CD4(+) T cell responses against MAGE-6 in HLA-DRB10401(+) patients with renal cell carcinoma or melanoma.	MAGEA6 HLA-DRB1	2.16e-05	2	162	2	12208877
Pubmed	Activation of Alpha 7 Cholinergic Nicotinic Receptors Reduce Blood-Brain Barrier Permeability following Experimental Traumatic Brain Injury.	CHRNA7 CHRFAM7A	2.16e-05	2	162	2	26937017
Pubmed	DRB1*03 diversity and DRB3 associations in five major population groups in the United States.	HLA-DRB1 HLA-DRB3	2.16e-05	2	162	2	11872240
Pubmed	Diminished α7 nicotinic acetylcholine receptor (α7nAChR) rescues amyloid-β induced atrial remodeling by oxi-CaMKII/MAPK/AP-1 axis-mediated mitochondrial oxidative stress.	CHRNA7 CHRFAM7A	2.16e-05	2	162	2	36603528
Pubmed	Activation of α7nAChR Promotes Diabetic Wound Healing by Suppressing AGE-Induced TNF-α Production.	CHRNA7 CHRFAM7A	2.16e-05	2	162	2	26650489
Pubmed	Lack of modulation of nicotinic acetylcholine alpha-7 receptor currents by kynurenic acid in adult hippocampal interneurons.	CHRNA7 CHRFAM7A	2.16e-05	2	162	2	22848433
Pubmed	Functional interaction of histone deacetylase 5 (HDAC5) and lysine-specific demethylase 1 (LSD1) promotes breast cancer progression.	HDAC5 KDM1A	2.16e-05	2	162	2	27212032
Pubmed	Impaired attention is central to the cognitive deficits observed in alpha 7 deficient mice.	CHRNA7 CHRFAM7A	2.16e-05	2	162	2	16650968
Pubmed	Microglial cell response in α7 nicotinic acetylcholine receptor-deficient mice after systemic infection with Escherichia coli.	CHRNA7 CHRFAM7A	2.16e-05	2	162	2	35413868
Pubmed	Skeletal and cardiac ryanodine receptors exhibit different responses to Ca2+ overload and luminal ca2+.	RYR1 RYR2	2.16e-05	2	162	2	17259277
Pubmed	Long-term improvements in sensory inhibition with gestational choline supplementation linked to α7 nicotinic receptors through studies in Chrna7 null mutation mice.	CHRNA7 CHRFAM7A	2.16e-05	2	162	2	24462939
Pubmed	Probing the putative α7 nAChR/NMDAR complex in human and murine cortex and hippocampus: Different degrees of complex formation in healthy and Alzheimer brain tissue.	CHRNA7 CHRFAM7A	2.16e-05	2	162	2	29261717
Pubmed	A cellular and functional split in the DRw8 haplotype is due to a single amino acid replacement (DR beta ser 57- asp 57).	HLA-DRB1 HLA-DRB3	2.16e-05	2	162	2	2497068
Pubmed	Altered hippocampal circuit function in C3H alpha7 null mutant heterozygous mice.	CHRNA7 CHRFAM7A	2.16e-05	2	162	2	18199426
Pubmed	Stroke-induced activation of the α7 nicotinic receptor increases Pseudomonas aeruginosa lung injury.	CHRNA7 CHRFAM7A	2.16e-05	2	162	2	22490926
Pubmed	Dendritic spine alterations in the hippocampus and parietal cortex of alpha7 nicotinic acetylcholine receptor knockout mice.	CHRNA7 CHRFAM7A	2.16e-05	2	162	2	23270857
Pubmed	Neuronal nicotinic alpha7 receptors modulate inflammatory cytokine production in the skin following ultraviolet radiation.	CHRNA7 CHRFAM7A	2.16e-05	2	162	2	18077004
Pubmed	Smoking in adult attention-deficit/hyperactivity disorder: interaction between 15q13 nicotinic genes and Temperament Character Inventory scores.	CHRNA7 CHRFAM7A	2.16e-05	2	162	2	19462340
Pubmed	Performance deficit of alpha7 nicotinic receptor knockout mice in a delayed matching-to-place task suggests a mild impairment of working/episodic-like memory.	CHRNA7 CHRFAM7A	2.16e-05	2	162	2	16923147
Pubmed	NMR structural analysis of alpha-bungarotoxin and its complex with the principal alpha-neurotoxin-binding sequence on the alpha 7 subunit of a neuronal nicotinic acetylcholine receptor.	CHRNA7 CHRFAM7A	2.16e-05	2	162	2	11790782
Pubmed	Ryanodine receptor oligomeric interaction: identification of a putative binding region.	RYR1 RYR2	2.16e-05	2	162	2	14722100
Pubmed	Structural and functional interactions within ryanodine receptor.	RYR1 RYR2	2.16e-05	2	162	2	26009179
Pubmed	Genetic deletion of α7 nAChRs reduces hippocampal granule and pyramidal cell number in both sexes but impairs pattern separation in males only.	CHRNA7 CHRFAM7A	2.16e-05	2	162	2	37746145
Pubmed	A 2-base pair deletion polymorphism in the partial duplication of the alpha7 nicotinic acetylcholine gene (CHRFAM7A) on chromosome 15q14 is associated with schizophrenia.	CHRNA7 CHRFAM7A	2.16e-05	2	162	2	19631623
Pubmed	Deletion of the alpha7 nicotinic receptor subunit gene results in increased sensitivity to several behavioral effects produced by alcohol.	CHRNA7 CHRFAM7A	2.16e-05	2	162	2	15770102
Pubmed	Cortical synaptic NMDA receptor deficits in α7 nicotinic acetylcholine receptor gene deletion models: implications for neuropsychiatric diseases.	CHRNA7 CHRFAM7A	2.16e-05	2	162	2	24326163
Pubmed	The conundrum of HLA-DRB114:01/14:54 and HLA-DRB302:01/02:02 mismatches in unrelated hematopoietic SCT.	HLA-DRB1 HLA-DRB3	2.16e-05	2	162	2	20972469
Pubmed	Functional role of alpha7 nicotinic receptor in chronic neuropathic and inflammatory pain: studies in transgenic mice.	CHRNA7 CHRFAM7A	2.16e-05	2	162	2	23811428
Pubmed	Alpha 7 subunit of nAChR regulates migration of human mesenchymal stem cells.	CHRNA7 CHRFAM7A	2.16e-05	2	162	2	20720594
Pubmed	Structure and Function of the Human Ryanodine Receptors and Their Association with Myopathies-Present State, Challenges, and Perspectives.	RYR1 RYR2	2.16e-05	2	162	2	32899693
Pubmed	Impaired performance of alpha7 nicotinic receptor knockout mice in the five-choice serial reaction time task.	CHRNA7 CHRFAM7A	2.16e-05	2	162	2	17019565
Pubmed	Dilinoleoylphosphatidylcholine ameliorates scopolamine-induced impairment of spatial learning and memory by targeting alpha7 nicotinic ACh receptors.	CHRNA7 CHRFAM7A	2.16e-05	2	162	2	19100751
Pubmed	Activation of the α7 Nicotinic Acetylcholine Receptor Prevents against Microglial-Induced Inflammation and Insulin Resistance in Hypothalamic Neuronal Cells.	CHRNA7 CHRFAM7A	2.16e-05	2	162	2	35883638
Pubmed	Chrna7 genotype is linked with alpha7 nicotinic receptor expression but not alpha7 RNA levels.	CHRNA7 CHRFAM7A	2.16e-05	2	162	2	19368846
Pubmed	Alpha7-nicotinic acetylcholine receptors mediate an Abeta(1-42)-induced increase in the level of acetylcholinesterase in primary cortical neurones.	CHRNA7 CHRFAM7A	2.16e-05	2	162	2	15009674
Pubmed	Hydroxynorketamine, but not ketamine, acts via α7 nicotinic acetylcholine receptor to control presynaptic function and gene expression.	CHRNA7 CHRFAM7A	2.16e-05	2	162	2	38253622
Pubmed	The role of dorsal root ganglia alpha-7 nicotinic acetylcholine receptor in complete Freund's adjuvant-induced chronic inflammatory pain.	CHRNA7 CHRFAM7A	2.16e-05	2	162	2	34514543
Pubmed	α7 nicotinic acetylcholine receptor (α7nAChR) expression in bone marrow-derived non-T cells is required for the inflammatory reflex.	CHRNA7 CHRFAM7A	2.16e-05	2	162	2	22183893
Pubmed	Mice deficient in the alpha7 neuronal nicotinic acetylcholine receptor lack alpha-bungarotoxin binding sites and hippocampal fast nicotinic currents.	CHRNA7 CHRFAM7A	2.16e-05	2	162	2	9364063
Pubmed	Evidence suggesting that the mouse sperm acrosome reaction initiated by the zona pellucida involves an alpha7 nicotinic acetylcholine receptor.	CHRNA7 CHRFAM7A	2.16e-05	2	162	2	12606407
Pubmed	Genetic variations in CHRNA7 or CHRFAM7 and susceptibility to dementia.	CHRNA7 CHRFAM7A	2.16e-05	2	162	2	22300029
Pubmed	GTS-21 ameliorates polymicrobial sepsis-induced hepatic injury by modulating autophagy through α7nAchRs in mice.	CHRNA7 CHRFAM7A	2.16e-05	2	162	2	32018068
Pubmed	Development of a new HLA-DRB real-time PCR typing method.	HLA-DRB1 HLA-DRB3	2.16e-05	2	162	2	15620466
Pubmed	CHRNA7 and CHRFAM7A mRNAs: co-localized and their expression levels altered in the postmortem dorsolateral prefrontal cortex in major psychiatric disorders.	CHRNA7 CHRFAM7A	2.16e-05	2	162	2	26206074
Pubmed	Nicotine elicits prolonged calcium signaling along ventral hippocampal axons.	CHRNA7 CHRFAM7A	2.16e-05	2	162	2	24349346
Pubmed	The role of nicotinic acetylcholine receptor (nAChR) α7 subtype in the functional interaction between nicotine and ethanol in mouse cerebellum.	CHRNA7 CHRFAM7A	2.16e-05	2	162	2	21143250
Pubmed	Regulation of anti-cyclic citrullinated peptide antibodies in rheumatoid arthritis: contrasting effects of HLA-DR3 and the shared epitope alleles.	HLA-DRB1 HLA-DRB3	2.16e-05	2	162	2	16320316
Pubmed	Cholinergic modulation of appetite-related synapses in mouse lateral hypothalamic slice.	CHRNA7 CHRFAM7A	2.16e-05	2	162	2	16319313
Pubmed	Impaired synaptic plasticity in the visual cortex of mice lacking α7-nicotinic receptor subunit.	CHRNA7 CHRFAM7A	2.16e-05	2	162	2	25797465
Pubmed	Pharmacologic activation of cholinergic alpha7 nicotinic receptors mitigates depressive-like behavior in a mouse model of chronic stress.	CHRNA7 CHRFAM7A	2.16e-05	2	162	2	29197398
Pubmed	Cholinergic signaling via the α7 nicotinic acetylcholine receptor regulates the migration of monocyte-derived macrophages during acute inflammation.	CHRNA7 CHRFAM7A	2.16e-05	2	162	2	38178134
Pubmed	In hippocampal oriens interneurons anti-Hebbian long-term potentiation requires cholinergic signaling via α7 nicotinic acetylcholine receptors.	CHRNA7 CHRFAM7A	2.16e-05	2	162	2	23325242
Pubmed	Glutamatergic synapse formation is promoted by α7-containing nicotinic acetylcholine receptors.	CHRNA7 CHRFAM7A	2.16e-05	2	162	2	22649244
Pubmed	Broad-spectrum efficacy across cognitive domains by alpha7 nicotinic acetylcholine receptor agonism correlates with activation of ERK1/2 and CREB phosphorylation pathways.	CHRNA7 CHRFAM7A	2.16e-05	2	162	2	17898229
Pubmed	Alpha7-nicotinic receptors modulate nicotine-induced reinforcement and extracellular dopamine outflow in the mesolimbic system in mice.	CHRNA7 CHRFAM7A	2.16e-05	2	162	2	21901321
Pubmed	Dopamine release in prefrontal cortex in response to beta-amyloid activation of alpha7 * nicotinic receptors.	CHRNA7 CHRFAM7A	2.16e-05	2	162	2	17935702
Pubmed	The function of glutamatergic synapses is not perturbed by severe knockdown of 4.1N and 4.1G expression.	EPB41L1 EPB41L2	2.16e-05	2	162	2	19225127
Pubmed	Neuronal nicotinic alpha7 receptors modulate early neutrophil infiltration to sites of skin inflammation.	CHRNA7 CHRFAM7A	2.16e-05	2	162	2	20624304
Pubmed	Cytokine-induced alterations of α7 nicotinic receptor in colonic CD4 T cells mediate dichotomous response to nicotine in murine models of Th1/Th17- versus Th2-mediated colitis.	CHRNA7 CHRFAM7A	2.16e-05	2	162	2	21784975
Pubmed	Lack of acetylcholine nicotine alpha 7 receptor suppresses development of collagen-induced arthritis and adaptive immunity.	CHRNA7 CHRFAM7A	2.16e-05	2	162	2	20659128
Pubmed	Stimulation of α7 nicotinic acetylcholine receptor by nicotine increases suppressive capacity of naturally occurring CD4+CD25+ regulatory T cells in mice in vitro.	CHRNA7 CHRFAM7A	2.16e-05	2	162	2	20843956
Pubmed	Mice homozygous for the L250T mutation in the alpha7 nicotinic acetylcholine receptor show increased neuronal apoptosis and die within 1 day of birth.	CHRNA7 CHRFAM7A	2.16e-05	2	162	2	10800961
Pubmed	Description of two new HLA-DRB alleles (DRB10310 and DRB301012) found in a Spanish infant.	HLA-DRB1 HLA-DRB3	2.16e-05	2	162	2	9234492
Pubmed	Characterization of allelic variants at chromosome 15q14 in schizophrenia.	CHRNA7 CHRFAM7A	2.16e-05	2	162	2	16417613
Pubmed	Absence of alpha7-containing neuronal nicotinic acetylcholine receptors does not prevent nicotine-induced seizures.	CHRNA7 CHRFAM7A	2.16e-05	2	162	2	11834293
Pubmed	Reduced Chrna7 expression in mice is associated with decreases in hippocampal markers of inhibitory function: implications for neuropsychiatric diseases.	CHRNA7 CHRFAM7A	2.16e-05	2	162	2	22314319
GeneFamily	Ryanodine receptors\|Protein phosphatase 1 regulatory subunits	RYR1 RYR2	1.02e-04	3	106	2	287
GeneFamily	Erythrocyte membrane protein band 4.1\|FERM domain containing	EPB41L1 EPB41L2	2.03e-04	4	106	2	951
GeneFamily	Abhydrolase domain containing	ABHD17A ABHD17C EPHX4	2.78e-04	22	106	3	4
GeneFamily	Argonaute/PIWI family	AGO1 AGO4	9.32e-04	8	106	2	408
GeneFamily	Adenosine deaminases acting on RNA	ADAR ADARB2	9.32e-04	8	106	2	1303
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	C2CD4B C2CD4A CCDC33	1.21e-03	36	106	3	823
GeneFamily	Progestin and adipoQ receptor family	PAQR5 PAQR3	1.81e-03	11	106	2	930
GeneFamily	Fibronectin type III domain containing	COL7A1 PRTG MYOM1 MID2 LRRN3	2.52e-03	160	106	5	555
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	HSPG2 PRTG MYOM1 LRRN3 HMCN2	2.59e-03	161	106	5	593
GeneFamily	WD repeat domain containing	WDR4 COP1 WDR74 SNRNP40 TAF5L DCAF11	4.46e-03	262	106	6	362
ToppCell	Bronchus_Control_(B.)-Stromal-TX-Fibroblasts-3\|Bronchus_Control_(B.) / Sample group, Lineage and Cell type	NID2 HSPA12B FGF16 FAP HOXC8 HMCN2 AEBP1 OLFML1 C1QTNF7	4.34e-08	199	159	9	07b8c33342c62afd9c63ec2d757cfa3ba65d2a98
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma-3\|TCGA-Brain / Sample_Type by Project: Shred V9	PRTG CELA2A CSMD2 AGO1 AGO4 ASXL3 MACO1 KDM1A	6.65e-08	149	159	8	768877bade04ca0321593b8470b5011ad8270431
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	HSPG2 HLA-DRB1 ITGA5 HSPA12B HMCN2 LHFPL6 BTNL9 PLXNA2	5.43e-07	196	159	8	a20a56d8997d6db2a10046c8801c619a379de83c
ToppCell	10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_immature-Tip-like-A\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	NID2 HSPG2 C2CD4B CUBN HSPA12B EPHX4 BTNL9 PLXNA2	5.64e-07	197	159	8	9e948b2e0f7e426f1e6f95bbbf4282fbddc2b99d
ToppCell	10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_arterial-F\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	NID2 HSPG2 C2CD4B ITGA5 HSPA12B EPHX4 BTNL9 PLXNA2	6.09e-07	199	159	8	463ba77dc4c85eebb343f29a42c7ac889b0497c9
ToppCell	facs-Marrow-T-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STAB2 ERN2 GCNT4 PTH2R ADD2 AEBP1 PLXNA2	1.64e-06	158	159	7	f296ca24fdedc33f1d24b79e7660763114ce7fa3
ToppCell	facs-Marrow-T-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STAB2 ERN2 GCNT4 PTH2R ADD2 AEBP1 PLXNA2	1.64e-06	158	159	7	8c7108f2c40d97a317762ba0b8eca76542b2ebaf
ToppCell	COVID-19-kidney-Technical/muscle_(Mes)\|kidney / Disease (COVID-19 only), tissue and cell type	FAT3 GABBR2 CSMD2 RYR1 RYR2 SEMA3A CNTNAP2	1.71e-06	159	159	7	5335cbcdeaf2bbd0268bbfe0e45c8c0d288e640d
ToppCell	Adult-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D122\|Adult / Lineage, Cell type, age group and donor	GABBR2 HSPA12B SEMA3A LHFPL6 BTNL9 PLXNA2 EPB41L2	2.78e-06	171	159	7	bd20e85d36fa9d7ddc8afef6a1dea75efc9ee1dc
ToppCell	10x5'v1-week_17-19-Myeloid_neutrophil-granulo-eo/baso/mast-eosinophil\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	PRTG PAQR5 PTH2R LRRN3 FCGBP TENM1 PLXNA2	3.76e-06	179	159	7	d16dc58b5b22762a5a3c875563ced18022d08908
ToppCell	Control-Endothelial_cells-Capillary_endothelial_cells\|Control / group, cell type (main and fine annotations)	ITGA5 HSPA12B SEMA3A KCTD3 LHFPL6 BTNL9 EPB41L2	3.90e-06	180	159	7	b043f9ffb9a4cd427a15bebb86a711c7b08866e8
ToppCell	COVID-19-Endothelial_cells-Capillary_endothelial_cells\|COVID-19 / group, cell type (main and fine annotations)	LAMA5 GABBR2 HSPA12B SEMA3A LHFPL6 BTNL9 PLXNA2	4.05e-06	181	159	7	c5f9c92af1384d9089c65afdf41c6feb8345a3ae
ToppCell	NS-moderate-d_16-33-Lymphoid-NK\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	NID2 COL7A1 PRTG FAP AEBP1 OLFML1 LHFPL6	4.20e-06	182	159	7	fb503f8ecd013f1f2161a5841572b57cfcddb6fa
ToppCell	droplet-Lung-nan-3m-Endothelial-endothelial_cell_of_lymphatic_vessel\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TCAF1 GLIS3 NEU3 SEMA3A PIGA KBTBD11 BTNL9	4.67e-06	185	159	7	6a85399cfdb9b89683c874e7f046957f9a601dc2
ToppCell	moderate-Lymphoid-NK\|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	NID2 COL7A1 PRTG FAP AEBP1 OLFML1 LHFPL6	4.67e-06	185	159	7	4979a787acbc9b4ca8defe91cc79b674e51af1bf
ToppCell	droplet-Lung-nan-3m-Endothelial-Lymphatic_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TCAF1 GLIS3 NEU3 SEMA3A PIGA KBTBD11 BTNL9	4.67e-06	185	159	7	64791056cdbb739136dbef08f4b16e2b5427faad
ToppCell	5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NID2 STAB2 SLC26A4 SEMA3A KBTBD11 LHFPL6 EPB41L2	4.84e-06	186	159	7	40070d9cd20188ba49b32acfca9bc16256b38bf5
ToppCell	ASK440-Mesenchymal\|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq	EGFL6 FAP AEBP1 OLFML1 TENM1 C1QTNF7 EPB41L2	5.76e-06	191	159	7	f12959eebb4167e1aa03de05d7711a702c58b3c9
ToppCell	ASK440-Mesenchymal-Fibroblast\|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq	EGFL6 FAP AEBP1 OLFML1 TENM1 C1QTNF7 EPB41L2	5.76e-06	191	159	7	387296b5377ef6839f0812e5b3529a10b5f7d530
ToppCell	facs-Pancreas-Exocrine-3m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NID2 HSPG2 FAP AEBP1 OLFML1 LHFPL6 C1QTNF7	5.96e-06	192	159	7	8937a59f6bbe07f671bdabbd3707dc9c17a14cd9
ToppCell	facs-Pancreas-Exocrine-3m-Mesenchymal\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NID2 HSPG2 FAP AEBP1 OLFML1 LHFPL6 C1QTNF7	5.96e-06	192	159	7	e4a7f2673f801b008ca67291db2fb2b9fd2955b8
ToppCell	facs-Pancreas-Exocrine-3m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NID2 HSPG2 FAP AEBP1 OLFML1 LHFPL6 C1QTNF7	5.96e-06	192	159	7	ac1477433704573f95111eee6263b93668d2845e
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MYOM1 FAT3 RYR2 HMCN2 AEBP1 LHFPL6 EPB41L2	6.82e-06	196	159	7	1522958a92e0126326a9f0d9fb1c5b5c50b001ea
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FAT3 RYR2 FAP LRRN3 AEBP1 OLFML1 C1QTNF7	6.82e-06	196	159	7	9737a5f006d37b549f281e1863aca558e1e4dc99
ToppCell	10x_3'_v2v3-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia_independent-F\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	LAMA5 ABHD17C FAP AEBP1 TENM1 CHRFAM7A CNR1	6.82e-06	196	159	7	b8b9801181d7604871b48aebacb295d0a57a5eaf
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MYOM1 FAT3 RYR2 HMCN2 AEBP1 LHFPL6 EPB41L2	6.82e-06	196	159	7	1c8294014713684b50885e638668f2ce75f357f0
ToppCell	10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_immature\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	NID2 HSPG2 C2CD4B HSPA12B EPHX4 BTNL9 PLXNA2	7.05e-06	197	159	7	62c0a90869431e582bb7bb329e0b0cc59123d3d1
ToppCell	COVID-19-Epithelial-Club,_Basal_cells\|Epithelial / Condition, Lineage and Cell class	RCBTB2 ERN2 TMEM71 RYR1 EGFL6 SEMA3A FCGBP	7.05e-06	197	159	7	78ed2810e5a765327e7a6da0ca5d4854bf7a0b6f
ToppCell	10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_immature-Tip-like\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	NID2 HSPG2 C2CD4B HSPA12B EPHX4 BTNL9 PLXNA2	7.05e-06	197	159	7	16f0eb047df9d702518f82ee99c6e7dc1350b2fb
ToppCell	Fibroblasts-HLA-DRA_high_Fibroblasts\|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	NID2 HSPG2 GLIS3 FAP AEBP1 OLFML1 LHFPL6	7.29e-06	198	159	7	e8c0fbf306fae13e97caa294d7c99a564bd97130
ToppCell	cellseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	FAT3 RYR2 FAP LRRN3 AEBP1 OLFML1 C1QTNF7	7.29e-06	198	159	7	f1374f7a50244d59c766ac41f44c08c9117407d2
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NID2 EGFL6 FAP LRRN3 OLFML1 CNTNAP2 LHFPL6	7.53e-06	199	159	7	83383d9ae4f501754fd3da0215ce6f0e3c70562c
ToppCell	cellseq-Mesenchymal-Fibroblastic-Fibroblastic_2\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	FAT3 RYR2 FAP LRRN3 AEBP1 OLFML1 C1QTNF7	7.53e-06	199	159	7	66a79732caf2f04c09b4d9832377aa01ca477677
ToppCell	10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_arterial\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	NID2 HSPG2 C2CD4B HSPA12B EPHX4 BTNL9 PLXNA2	7.53e-06	199	159	7	0602e2b2aa56d106da63bd342a38bef437b4d496
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Endothelial-Endothelial_immature-Tip-like-F\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	NID2 HSPG2 PRTG C2CD4B CUBN EPHX4 CHRFAM7A	7.53e-06	199	159	7	63c01e8961f48ed1bed4ab619cacf318cd6de7b9
ToppCell	10x_3'_v2v3-Non-neoplastic-Endothelial\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	NID2 HSPG2 C2CD4B HSPA12B EPHX4 BTNL9 PLXNA2	7.78e-06	200	159	7	061ba851f941c616ddb462512e826c412881c3ce
ToppCell	TCGA-Thryoid-Primary_Tumor-Thyroid_Papillary_Carcinoma-Tall_Cell-4\|TCGA-Thryoid / Sample_Type by Project: Shred V9	C2CD4B C2CD4A ADCY8 DHDH PLCD1 EPB41L1	1.22e-05	142	159	6	43524c10f446c9da079cff52800326a1d4675452
ToppCell	Posterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Bcl6\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	SLC26A4 AMDHD1 SPAG8 RYR1 FGF16 CFAP65	1.32e-05	144	159	6	08005be9e3367f78ef27e125d9cce5ca53f4bd2d
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VWA3A FAT3 ADCY8 RYR2 SEMA3A CNTNAP2	2.40e-05	160	159	6	c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCell	COVID-19-kidney-Epithelial_(EC)\|kidney / Disease (COVID-19 only), tissue and cell type	HSPG2 ITGA5 ADARB2 SEMA3A CNTNAP2 BTNL9	2.40e-05	160	159	6	0d4880f85565d8c540c94a8f8109147b3029279a
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VWA3A FAT3 ADCY8 RYR2 SEMA3A CNTNAP2	2.40e-05	160	159	6	25c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell	356C-Fibroblasts-Fibroblast-D\|356C / Donor, Lineage, Cell class and subclass (all cells)	COL7A1 C2CD4B NUMBL RYR2 SEMA3A OLFML1	2.95e-05	166	159	6	7286a37b2827f3747469ffd0d76cbe81116db7ee
ToppCell	356C-Fibroblasts-Fibroblast-D-\|356C / Donor, Lineage, Cell class and subclass (all cells)	COL7A1 C2CD4B NUMBL RYR2 SEMA3A OLFML1	2.95e-05	166	159	6	7c2eee0a4f45795a956acf936b85bdb35f1b1624
ToppCell	facs-Diaphragm-Limb_Muscle-24m\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYOM1 FAT3 CUBN RYR2 AEBP1 CNTNAP2	3.26e-05	169	159	6	12bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCell	Control-Fibroblasts-Pericytes\|Control / group, cell type (main and fine annotations)	NID2 ADARB2 RYR2 EGFL6 LHFPL6 EPB41L2	3.48e-05	171	159	6	080003f698f867935c2bfc55d241d3650f45a0ab
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1_VIP_PCDH20\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ADARB2 PCDH20 CHRNA7 RIMBP3 RIMBP3B CNR1	3.60e-05	172	159	6	35e961c88bfe79046533396912cedf00ca81db7b
ToppCell	5'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	VWA3A NID2 STAB2 SEMA3A KBTBD11 EPB41L2	3.72e-05	173	159	6	7dc988fc0ba29990567bf1bcdeb3faeeee507eb1
ToppCell	356C-Myeloid-Macrophage-FABP4+_Macrophage_3\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	HSPG2 EGFL6 SEMA3A FAP OLFML1 C1QTNF7	4.22e-05	177	159	6	3d955ea938a1d2fb1b6d68d4997fd454bd632dfc
ToppCell	metastatic_Lymph_Node-Endothelial_cells\|metastatic_Lymph_Node / Location, Cell class and cell subclass	HSPG2 STAB2 CYP46A1 SEMA3A ASXL3 LHFPL6	4.22e-05	177	159	6	71bf5d4bc67bda37a0499e5ec01af7dd5254041d
ToppCell	P28-Endothelial-lymphatic_endothelial_cell\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	NID2 STAB2 AMDHD1 SEMA3A KBTBD11 BTNL9	4.22e-05	177	159	6	6e330aa3c87fd640526b746a9deb3b2250d2518c
ToppCell	P28-Endothelial-lymphatic_endothelial_cell-endothelial_cell_of_lymphatic_vessel\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	NID2 STAB2 AMDHD1 SEMA3A KBTBD11 BTNL9	4.22e-05	177	159	6	e96a7e4544710aaab8bd2800ecff9667880a8bf4
ToppCell	TCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-6\|TCGA-Ovary / Sample_Type by Project: Shred V9	ITGA5 FAP AEBP1 OLFML1 LHFPL6 C1QTNF7	4.36e-05	178	159	6	142879e9393e721f9b05a6bb46995c9d6d713c95
ToppCell	droplet-Bladder-BLADDER-1m-Epithelial-endothelial_cell\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CCNJL FAT3 PCDH20 MTAP DHDH NETO1	4.50e-05	179	159	6	c7c74e26bbf86c5326ee38bac7de111d5414f46b
ToppCell	ASK454-Endothelial-Lymphatic\|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq	NID2 SLC26A4 SPAG8 SEMA3A KBTBD11 TAF5L	4.50e-05	179	159	6	fd84a79f76a01c0377dff5b20016b004d369f96f
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	WSCD1 HSPG2 C2CD4B ITGA5 GABBR2 BTNL9	4.78e-05	181	159	6	9bfd93cf053beaee806cacdffd7abef02f94aec6
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NID2 FAT3 FAP AEBP1 LHFPL6 EPB41L2	4.78e-05	181	159	6	c6d2a13df3b74fade3b0c71e285b4c14c8e52413
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_ADARB2_ADAM33\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ADARB2 CHRNA7 EGFL6 LRRN3 CHRFAM7A CNR1	4.78e-05	181	159	6	2f3d04d22d4ac016e61709ea5af3d48885c946c4
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	VWA3A FAT3 RYR2 FAP LRRN3 C1QTNF7	4.78e-05	181	159	6	9ede19228ba5c0668a9c06c915510b95585216ef
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NID2 FAT3 FAP AEBP1 LHFPL6 EPB41L2	4.78e-05	181	159	6	c62b0a2422377ffadaab63edd538e87a06fa5017
ToppCell	PND01-03-samps-Mesenchymal-Myofibroblast\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	COL7A1 PCDH20 FGF16 FAP AEBP1 OLFML1	4.93e-05	182	159	6	812dac35b9aa05be48258082e007f6c00e7b4dd8
ToppCell	facs-Kidney-nan-24m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CELA2A PAQR5 EGFL6 FCGBP COX5A CTRL	4.93e-05	182	159	6	b8be66a867ea1bbae0820b26dbd55b68611f5ad5
ToppCell	5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NID2 STAB2 SLC26A4 SEMA3A KBTBD11 LHFPL6	4.93e-05	182	159	6	53c267ee327e116dbd89d5927ed3bdf78d25ee62
ToppCell	facs-Kidney-nan-24m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CELA2A PAQR5 EGFL6 FCGBP COX5A CTRL	4.93e-05	182	159	6	cb488f9a9b200e2557335ccf22535cd247512cdc
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_ADARB2_ADAM33\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ADARB2 CHRNA7 EGFL6 RTP5 CHRFAM7A CNR1	5.08e-05	183	159	6	6e6128c5be5e0a2db6d84eecbf4dddd02d0216f8
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)-Goblet_(bronchial)_L.0.4.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SLC26A4 ERN2 MAP3K4 FCGBP TCF25 MUC6	5.24e-05	184	159	6	01c19a830348ab0b9c02c1546a439de70ee10f97
ToppCell	5'-Adult-Distal_Rectal-Mesenchymal-fibroblastic-mLN_Stroma_(FMO2+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ITGA5 CSMD2 AEBP1 TENM1 LHFPL6 CHRFAM7A	5.40e-05	185	159	6	9faa35ceb89ccd2979072286f063687c9f846ce3
ToppCell	CV-Moderate-7\|Moderate / Virus stimulation, Condition and Cluster	UBR2 HUWE1 MAP3K4 KMT2D NUP155 TMEM131L	5.40e-05	185	159	6	a6c9203ce6c2892a4a369c9bcfb85720f01cbb3f
ToppCell	droplet-Liver-LIVER_HEP-30m-Endothelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WSCD1 HSPG2 LAMA5 FHL3 MUC6 EPB41L2	5.40e-05	185	159	6	bdd2e6cb20294b39a9d856004bf57ba69cf877e2
ToppCell	droplet-Kidney-nan-18m-Epithelial-Epcam____podocyte-3\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	C2CD4B CELA2A NEU3 FCGBP PLCD1 EPHX4	5.56e-05	186	159	6	29c79b5a29907d4f3f87ad2ca04840c0f15b7d4e
ToppCell	TCGA-Kidney-Primary_Tumor-Renal_Cell_Carcinoma-Kidney_Clear_Cell_Renal_Carcinoma-2\|TCGA-Kidney / Sample_Type by Project: Shred V9	NID2 ITGA5 FAP OLFML1 LHFPL6 FHL3	5.56e-05	186	159	6	1e6526fc9e9381b7ace864588cc7bd80194338d6
ToppCell	356C-Endothelial_cells-Endothelial-E-\|356C / Donor, Lineage, Cell class and subclass (all cells)	WSCD1 HSPG2 C2CD4A CUBN HMCN2 EPHX4	5.56e-05	186	159	6	2e024097ee361eeb1d855a4edb8ac8cdad35da06
ToppCell	356C-Endothelial_cells-Endothelial-E\|356C / Donor, Lineage, Cell class and subclass (all cells)	WSCD1 HSPG2 C2CD4A CUBN HMCN2 EPHX4	5.56e-05	186	159	6	c3449e54454009973818fc1101933c6f0168258c
ToppCell	tumor_Lung-Endothelial_cells-Lymphatic_ECs\|tumor_Lung / Location, Cell class and cell subclass	STAB2 SLC26A4 HSPA12B CYP46A1 SEMA3A KBTBD11	5.73e-05	187	159	6	87ecdc5f24aced95a37e653429f0fc493ff4aa3e
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_ADARB2_ADAM33\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ADARB2 CHRNA7 EGFL6 LRRN3 CHRFAM7A CNR1	5.73e-05	187	159	6	02105c82a9ba79d2f19e002188377fc3440770c2
ToppCell	TCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Ductal_Carcinoma-6\|TCGA-Breast / Sample_Type by Project: Shred V9	NID2 ABAT GLIS3 FAP AEBP1 OLFML1	5.73e-05	187	159	6	a96495803ba13fcfadd1d83b3cf5774f3fed0a20
ToppCell	wk_08-11-Endothelial-Blood_vessel_endothelial-GRIA2+_arterial_endo\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	ABHD17A HSPG2 C2CD4A ITGA5 NETO1 BTNL9	5.73e-05	187	159	6	a27aa97aa6508a3ffe92c2b6bb0511a95650a390
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6-Inh_L1_PAX6_CA4\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CUBN ADARB2 ADCY8 CHRNA7 CHRFAM7A CNR1	5.90e-05	188	159	6	ee572246e0c2f41bdbc29a03edc67b831af95c09
ToppCell	facs-Pancreas-Endocrine-24m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	C2CD4B C2CD4A DNAAF9 PER3 CNTNAP2 SETD7	5.90e-05	188	159	6	a91443aa8fa8fa87f7501c59219daa0305bd0bbf
ToppCell	ASK428-Endothelial-Lymphatic\|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq	STAB2 SLC26A4 HSPA12B SEMA3A LHFPL6 EPB41L2	5.90e-05	188	159	6	c371bc340966cfe9205cbf4b62c6452f49f2559f
ToppCell	nucseq-Endothelial-Endothelial_Vascular-Endothelial_capillary-CAP2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CDC42BPA HSPA12B KCTD3 LHFPL6 BTNL9 EPB41L2	6.08e-05	189	159	6	b6b4da51bc7f2c13a2f940540fdc61027d084835
ToppCell	moderate-Lymphoid-NK\|Lymphoid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	HSPG2 COL7A1 PRTG FAP AEBP1 LHFPL6	6.08e-05	189	159	6	22a19365782003c18ec8dddcdbfdaa82c4e330f6
ToppCell	ILEUM-non-inflamed-(7)_Endothelial_cell-(7)_Lymphatics\|(7)_Endothelial_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	STAB2 GLIS3 SEMA3A FCGR2A KBTBD11 EPB41L2	6.26e-05	190	159	6	9ce301841ce9486701fa28eb2a9929e35d476878
ToppCell	Children_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	LAMA5 HSPA12B SEMA3A LHFPL6 BTNL9 EPB41L2	6.26e-05	190	159	6	0a351609a72fd638c84b2435782e312ee6a33aac
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NID2 FAT3 FAP AEBP1 LHFPL6 EPB41L2	6.44e-05	191	159	6	107113b930d9ad171f1b2aa20df4567c94fae7d8
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NID2 FAT3 FAP AEBP1 LHFPL6 EPB41L2	6.44e-05	191	159	6	bc353a79a1d11ca52bba5e3874a80d432e1a7715
ToppCell	367C-Endothelial_cells-Endothelial-F_(Lymphatics)\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	STAB2 SLC26A4 SEMA3A FCGR2A OLFML1 KBTBD11	6.63e-05	192	159	6	5e709c0714e8eba27e03a6def0544256bedb3ced
ToppCell	367C-Endothelial_cells-Endothelial-F_(Lymphatics)-\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	STAB2 SLC26A4 SEMA3A FCGR2A OLFML1 KBTBD11	6.63e-05	192	159	6	5f4f44f15d3a2846981e68296643a4634930a211
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FAT3 GLIS3 RYR2 AEBP1 LHFPL6 C1QTNF7	6.63e-05	192	159	6	3d0cb19f037f604253d7d728689aeaa94251e92b
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts-Peribronchial_fibroblasts_L.2.1.3.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NID2 FAP AEBP1 OLFML1 LHFPL6 C1QTNF7	6.63e-05	192	159	6	b9e4585bea280ca0ae159f0c6a2bf7b88a15a6e6
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	HSPG2 HLA-DRB1 ITGA5 HSPA12B LHFPL6 BTNL9	6.63e-05	192	159	6	28eb3a5728e8901bcb5ba12f6b009f41b065fa37
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Degenerative_Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FAP HMCN2 AEBP1 NETO1 LHFPL6 FHL3	6.83e-05	193	159	6	dc8e62df6121ee99b156aca6b1b3ae555739b6f2
ToppCell	NS-moderate-d_0-4\|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	VWA3A GLIS3 SPAG8 CFAP65 PLXNA2 CCDC33	6.83e-05	193	159	6	ea345d34440b25f65358a53dc72831998d1c3620
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	HSPG2 ITGA5 HSPA12B HMCN2 LHFPL6 BTNL9	6.83e-05	193	159	6	cc355b2ed6510619cad969ae074126d7c8db784d
ToppCell	10x3'2.3-week_14-16-Mesenchymal_fibro-stroma-arteriolar_fibroblast\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	EGFL6 FAP OLFML1 ASXL3 LHFPL6 C1QTNF7	6.83e-05	193	159	6	09de51f8ac509e03d480ed3dc9dfe7e7defc59cb
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_119\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FAP HMCN2 AEBP1 NETO1 LHFPL6 FHL3	6.83e-05	193	159	6	e2ee077fd381bd906e6b4329f22e7d106e422a7f
ToppCell	Control-CD8+_T_activated\|World / Disease group and Cell class	ZNF689 MAML1 LRRN3 FCGBP MROH6	6.83e-05	119	159	5	83c3e2bb71b947facbfbef635550901f33c8c26a
ToppCell	nucseq-Mesenchymal-Myocytic\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	COL7A1 ADARB2 RYR2 EGFL6 FAP AEBP1	7.02e-05	194	159	6	2d66091097e106c7bee22e5281f50724700bdf8d
ToppCell	LPS-antiTNF-Stromal_mesenchymal\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FAT3 GLIS3 RYR2 AEBP1 LHFPL6 C1QTNF7	7.02e-05	194	159	6	6e13549f697f7478b34fe71f7dd9d63c5d3db22e
ToppCell	(4)_Endothelial_cells-(4)_Lymph_vessel\|(4)_Endothelial_cells / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)	STAB2 SEMA3A FCGR2A OLFML1 KBTBD11 EPB41L2	7.02e-05	194	159	6	9735b86d3b2480a0b34d8aab8e7bd609d83c2454
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	HSPG2 HSPA12B HMCN2 LHFPL6 BTNL9 PLXNA2	7.22e-05	195	159	6	6bdef651cf73d7381e5012d0eb3c809138fb6b92
Drug	N6-cyclopentyl-9-methyladenine	GABBR2 ADAR ADARB2 CNR1	1.52e-06	13	158	4	CID000004401
Drug	LMWH	NID2 HSPG2 COL7A1 NRDC LAMA5 NEU3 ADCY8 CHRNA7 RYR1 RYR2 SEMA3A FCGR2A NETO1 FGF11 C4BPA CTRL CHRFAM7A	3.84e-06	663	158	17	CID000000772
Drug	NF T	CYP46A1 CHRNA7 RYR1 COX5A NETO1 PLCD1 CTRL CHRFAM7A CNR1	7.48e-06	190	158	9	CID006436102
Drug	Avermectin B1 [71751-41-2]; Up 200; 4.8uM; PC3; HT_HG-U133A	CCNJL HDAC5 GABBR2 RYR1 HOXC8 AGO4 PER3 TENM1 PLCD1	1.09e-05	199	158	9	5864_UP
Disease	Motor retardation	ABAT ERCC6 HACE1	1.04e-05	9	149	3	C0424230
Disease	T-Cell Lymphoma	KMT2D ASXL3 KDM1A	6.73e-05	16	149	3	C0079772
Disease	congenital myopathy 1A (implicated_via_orthology)	RYR1 RYR2	7.57e-05	3	149	2	DOID:3529 (implicated_via_orthology)
Disease	malignant hyperthermia (implicated_via_orthology)	RYR1 RYR2	7.57e-05	3	149	2	DOID:8545 (implicated_via_orthology)
Disease	advanced sleep phase syndrome (is_implicated_in)	AANAT PER3	1.51e-04	4	149	2	DOID:0050628 (is_implicated_in)
Disease	Withdrawal Symptoms	ADCY8 CHRNA7 PER3 CNR1	2.14e-04	58	149	4	C0087169
Disease	Drug Withdrawal Symptoms	ADCY8 CHRNA7 PER3 CNR1	2.14e-04	58	149	4	C0086189
Disease	Substance Withdrawal Syndrome	ADCY8 CHRNA7 PER3 CNR1	2.14e-04	58	149	4	C0038587
Disease	cognitive disorder (implicated_via_orthology)	CHRNA7 CHRFAM7A	3.75e-04	6	149	2	DOID:1561 (implicated_via_orthology)
Disease	rheumatoid arthritis (biomarker_via_orthology)	CHRNA7 CHRFAM7A	3.75e-04	6	149	2	DOID:7148 (biomarker_via_orthology)
Disease	Human papillomavirus infectious disease (is_implicated_in)	HLA-DRB1 ADAR	3.75e-04	6	149	2	DOID:11166 (is_implicated_in)
Disease	extranodal nasal NK/T cell lymphoma	HLA-DRB1 HLA-DRB3	3.75e-04	6	149	2	MONDO_0019472
Disease	Autistic Disorder	ABAT HLA-DRB1 COP1 GABBR2 CHRNA7 AGO1 CNTNAP2	3.77e-04	261	149	7	C0004352
Disease	schizophrenia (implicated_via_orthology)	CHRNA7 LRRN3 CHRFAM7A CNR1	3.96e-04	68	149	4	DOID:5419 (implicated_via_orthology)
Disease	Developmental Psychomotor Disorders	ABAT ERCC6	5.23e-04	7	149	2	C0751456
Disease	Psychomotor Disorders	ABAT ERCC6	5.23e-04	7	149	2	C0033922
Disease	peripheral neuropathy, response to vincristine	FAT3 NDUFAF6	5.23e-04	7	149	2	EFO_0003100, EFO_0006950
Disease	lymphedema, filarial elephantiasis	HLA-DRB1 ERN2	5.23e-04	7	149	2	EFO_0007272, MONDO_0019297
Disease	factor VIII measurement, venous thromboembolism	STAB2 GTF3C4 C4BPA	6.73e-04	34	149	3	EFO_0004286, EFO_0004630
Disease	susceptibility to plantar warts measurement	HLA-DRB1 HLA-DRB3 CNTNAP2 SLC38A7	1.14e-03	90	149	4	EFO_0008406
Disease	Microphthalmos	ERCC6 KMT2D	1.35e-03	11	149	2	C0026010
Disease	aspirin-induced respiratory disease (is_implicated_in)	HLA-DRB1 HLA-DRB3	1.35e-03	11	149	2	DOID:0080822 (is_implicated_in)
Disease	visual epilepsy (is_implicated_in)	FCGR2A CNTNAP2	1.35e-03	11	149	2	DOID:11832 (is_implicated_in)
Disease	nicotine dependence (implicated_via_orthology)	CHRNA7 CHRFAM7A	1.62e-03	12	149	2	DOID:0050742 (implicated_via_orthology)
Disease	response to antineoplastic agent	GLIS3 ADCY8 RYR2 SEMA3A	1.62e-03	99	149	4	GO_0097327
Disease	Schizophrenia	NUMBL HLA-DRB1 ACSM1 CSMD2 CHRNA7 CFAP65 SEMA3A CNTNAP2 CTRL CHRFAM7A PLXNA2 CNR1	1.80e-03	883	149	12	C0036341
Disease	Mental Depression	AANAT HDAC5 CSMD2 ADCY8 PER3 CNR1	1.89e-03	254	149	6	C0011570
Disease	autoimmune thrombocytopenic purpura (is_implicated_in)	HLA-DRB1 FCGR2A	2.55e-03	15	149	2	DOID:8924 (is_implicated_in)
Disease	temporal arteritis (is_implicated_in)	HLA-DRB1 FCGR2A	2.90e-03	16	149	2	DOID:13375 (is_implicated_in)
Disease	Bipolar Disorder	HDAC5 HLA-DRB1 ADCY8 CHRNA7 PER3 CNTNAP2 CHRFAM7A CNR1	3.02e-03	477	149	8	C0005586
Disease	adverse effect, response to xenobiotic stimulus	STAB2 ADARB2 MTAP	3.34e-03	59	149	3	EFO_0009658, GO_0009410
Disease	fasting blood glucose measurement	C2CD4B WDR4 FAT3 GLIS3 AGO1 NDUFAF6	3.46e-03	287	149	6	EFO_0004465
Disease	Depressive disorder	AANAT HDAC5 CSMD2 ADCY8 PER3 CNR1	3.58e-03	289	149	6	C0011581
Disease	lupus nephritis (is_implicated_in)	HLA-DRB1 FCGR2A	3.67e-03	18	149	2	DOID:0080162 (is_implicated_in)
Disease	osteoarthritis, hip, osteoarthritis, knee	HLA-DRB3 GLIS3 CCDC33	3.84e-03	62	149	3	EFO_0004616, EFO_1000786
Disease	response to mitochondrial complex I inhibitor	NUMBL GABBR2	4.09e-03	19	149	2	EFO_0600033
Disease	hepatitis B virus infection	HLA-DRB1 HLA-DRB3	4.09e-03	19	149	2	EFO_0004197
Disease	hypertension (implicated_via_orthology)	ABAT ADD2 PLCD1 CNR1	4.10e-03	128	149	4	DOID:10763 (implicated_via_orthology)
Disease	urinary microalbumin measurement	CUBN CNTNAP2	4.53e-03	20	149	2	EFO_0010967
Disease	Lymphoma, Follicular	HLA-DRB1 KMT2D	4.53e-03	20	149	2	C0024301

Protein segments in the cluster

Peptide	Gene	Start	Entry
FTTLVGGPEYVHCLL	PPP2R1A	76	P30153
YFPLCRASLHALVGS	ACOT1	366	Q86TX2
LYSLGPGERAHSTCG	ADCY8	91	P40145
YSCDPRFSLLGHASI	C4BPA	201	P04003
VKFSPSSRYHLAFGC	COP1	561	Q8NHY2
CNVSPGRHFVVLGEY	CTRL	76	P40313
HSIIPSDKGTYGCRF	BTNL9	121	Q6UXG8
LLASARQPGVCHYGT	EGFL6	31	Q8IUX8
GFHLEYKTVGLSSCP	CSMD2	1896	Q7Z408
PTARHCGSLAYSVAF	CCDC33	176	Q8N5R6
SAHLTLTEPYRGGCQ	AEBP1	821	Q8IUX7
HCTGNIGYTLFSSKP	FCGR2A	186	P12318
FYLCSHAGIQGTSRP	AGO1	746	Q9UL18
AAEPRHCLATTYGSS	CCNJL	406	Q8IV13
CVPGARYTVLFSHGN	ABHD17A	106	Q96GS6
VTSRCGGHSGSPILY	DOP1A	2411	Q5JWR5
CLAYVLHTSGTTGIP	AASDH	191	Q4L235
VHGIVSFGSRLGCNY	CELA2A	231	P08217
YLCSHAGIQGTSRPS	AGO4	751	Q9HCK5
SASHVGPFIDSYRCF	APEX2	236	Q9UBZ4
CGNYPTIHFGSTSFK	ASXL3	2151	Q9C0F0
YIGFRGLDGVHCVPT	CHRNA7	386	P36544
GTCSFPVRYLGHVEV	NUMBL	76	Q9Y6R0
ACLSYGSGPHIVLAT	RCBTB2	101	O95199
PQSFYDGSHSCARGV	MTAP	121	Q13126
PHYELCTLRGTGATA	NETO1	391	Q8TDF5
YVCHVVGTSGPLEAS	HSPG2	2216	P98160
FHLYVSTSPCGDARL	ADARB2	481	Q9NS39
HALTPAGVSCYTFQG	RIMBP3B	1031	A6NNM3
HALTPAGVSCYTFQG	RIMBP3C	1031	A6NJZ7
IFCSVSGYGVIPTLH	PAQR3	206	Q6TCH7
FGYRHPQSSATACIL	PAQR5	26	Q9NXK6
SSGAGIHPLCLVSRY	ERCC6	891	P0DP91
GRAGLHCTQAYPVRT	MAML1	951	Q92585
TTFDARPYRFHGTCT	MUC6	406	Q6W4X9
LFVGPFSCLGSYSRA	PCDH20	51	Q8N6Y1
PCSFVTHALLGSYAV	EPB41L1	206	Q9H4G0
YGAFGVPVKSLCHSA	FOXB2	341	Q5VYV0
LGFGSCHEELYSSRP	LRCH3	291	Q96II8
PIGHVYIFATCLGLS	MAGEA6	171	P43360
PSLGTHCYVRIKDSG	EPHX4	66	Q8IUS5
HFPRIQEGDSGLYSC	HMCN2	1401	Q8NDA2
VVGFCRGPAVSLQHY	CFAP65	456	Q6ZU64
LVHASPCRSSDGVFY	ERN2	111	Q76MJ5
ACSFQHSYRLLVPGS	ABAT	11	P80404
TTYGFCALLESPHTR	C2CD4B	96	A6NLJ0
LPCSFVTHALLGSYT	EPB41L2	326	O43491
AHCIGYPVVTLGFGF	MACO1	156	Q8N5G2
GISQCGYSSTIVHVP	PER3	626	P56645
HSYVSLPFGCTRAGV	PLXNA2	291	O75051
TCGSHFAVVILFFGP	OR4X2	231	Q8NGF9
QGIVTCLRATPYHGS	NDUFAF6	211	Q330K2
SPIHSTGQQFIYSGC	DCAF11	446	Q8TEB1
SGATPLYFACSHGQR	HACE1	196	Q8IYU2
CYFHGPSITTSLVFT	LMLN2	661	A0A1B0GTW7
GFPLTGTEARCYTNH	EXOG	66	Q9Y2C4
VSGCVGATRGFYPHL	MROH6	251	A6NGR9
ASFCPHGYGCRTLVV	LAMA5	1331	O15230
CLLLTPEGAFHSFGY	HSPA12B	106	Q96MM6
VSERHSCPLGFGHYS	GPR52	21	Q9Y2T5
PVSFGTFRRCSYPVH	LHFPL6	41	Q9Y693
IIDCTGTASYHGFLP	HUWE1	346	Q7Z6Z7
YIGFRGLDGVHCVPT	CHRFAM7A	296	Q494W8
VTHAGVRLYFSTCPF	NUP155	361	O75694
YSTGGQGPHRITCIY	OLFML1	331	Q6UWY5
PGGHVVYSTCSLSHL	NSUN4	301	Q96CB9
VIYCKSVHFGGFSSP	PLCD1	496	P51178
LQHAGVYVCRATTPG	PRTG	296	Q2VWP7
GLLYSSPHFTAECRF	FGF11	131	Q92914
FGCRPGSESHAGQIY	RABGGTB	181	P53611
DTTARCHPGTGVDYT	NID2	771	Q14112
RGYHTFCVGLGAIPS	PHF10	456	Q8WUB8
VRAHGSSILACAPLY	ITGA5	146	P08648
CGSHLSVVTLFYGTG	OR7C1	241	O76099
HITYLTSPSDLRCGG	CUBN	696	O60494
HNLLVCSVSGFYPGS	HLA-DRB3	141	P79483
VYVTRFGSHQCSGVL	C5orf47	16	Q569G3
LGSRSFVPDKGAHYC	FHL3	136	Q13643
TGSHLTVRNGYSCVP	KDM1A	561	O60341
IGRYDGTHPCLAAAT	BBS2	21	Q9BXC9
DPGTRCHYSTLAFSL	LACTBL1	171	A8MY62
SFHLYISTAPCGDGA	ADAR	956	P55265
TYFPFSLGHRSCIGQ	CYP46A1	426	Q9Y6A2
GFFYPSCTGSHLRSV	GCNT4	376	Q9P109
VCRAQGDPHYTTFDG	FCGBP	471	Q9Y6R7
DVTLPSSYHGAVCGL	FCGBP	3001	Q9Y6R7
VDVTLPSSYHGAVCG	FCGBP	4201	Q9Y6R7
EVYGHFLGVRGSCIP	GLIS3	191	Q8NEA6
CRYGAFGLPITVAHV	GSTK1	176	Q9Y2Q3
SYVSELAPRGHFVTC	FAT3	2401	Q8TDW7
GPLACSRTYFFGATH	DNAAF9	336	Q5TEA3
HNLLVCSVSGFYPGS	HLA-DRB1	141	P01911
RCAPSSRYTLLFSHG	ABHD17C	126	Q6PCB6
SLRCRPSYHFIGSLA	CNR1	146	P21554
DIGISATYCGAHSVP	AMDHD1	181	Q96NU7
GYTGHCPLLRFSVGQ	FAM166B	21	A8MTA8
CRFPQSVGRSHALVY	HOXC8	26	P31273
LQYPGEVHGSFTCSI	DHDH	216	Q9UQ10
HAYLPSIGGVDASCV	GABBR2	901	O75899
PYQVIGCSGFHLSSL	KHDC1	221	Q4VXA5
AVTGSTEACHPFVYG	COL7A1	2896	Q02388
EIHKYNTPGFTGCLS	CNTNAP2	1166	Q9UHC6
GSPRLILFTSAECHY	GADL1	206	Q6ZQY3
SPLGGYSVTARCFGH	HDAC5	971	Q9UQL6
PAVAIQSVRCYSHGS	COX5A	31	P20674
ICGIGSDYFDTTPHG	RYR1	4961	P21817
YFLSAASRPLCSGGH	RYR2	2981	Q92736
ERSSCGSVLFHGYLP	KCTD3	116	Q9Y597
YVTSFAICASGQPRG	C1QTNF7	6	Q9BXJ2
TAYGFCALLESPHTR	C2CD4A	101	Q8NCU7
APGSYVGACFDRLLH	IL17RC	696	Q8NAC3
CGPHLSVVSLFYGTI	OR1E3	241	Q8WZA6
GFSRHCLTSIYRPFV	MAP3K4	516	Q9Y6R4
HTPTVFYCVGLSASG	RTP5	321	Q14D33
HCGPVYSTRFLADSS	TAF5L	341	O75529
IAHGSLGFEPVYVSC	SPAG8	106	Q99932
FECGSIDPLTGSHYT	TMEM71	46	Q6P5X7
FSFHAVGPCAITVGS	AANAT	171	Q16613
CPYLGTHSEESRFGI	TMEM131L	661	A2VDJ0
FPLGLDSYHGCVIAA	TCAF1	246	Q9Y4C2
AGSYVSFHCRATAEP	LRRN3	436	Q9H3W5
PGLSHCSQLTTFYFG	PRAMEF14	371	Q5SWL7
HALTPAGVSCYTFQG	RIMBP3	1031	Q9UFD9
FHGTVLSIYCRPSSG	OR5L1	251	Q8NGL2
CGSHLIVVSLFYGTG	OR7G3	241	Q8NG95
YCRTGFHLEIFPNGT	FGF16	66	O43320
SHFLSLAYTPTCVIG	PSMD1	776	Q99460
RLKGHTSFVNSCYPA	SNRNP40	146	Q96DI7
LPHGFCTVTYSSTDR	SETD7	21	Q8WTS6
SVLTSYPILHFCGRA	SLC38A7	331	Q9NVC3
HDGFICTIRYRQTGP	TENM1	2006	Q9UKZ4
IGFVYHPTKETCLSG	ARHGAP5	546	Q13017
ALYFPVLIVHGDSGC	TMEM151A	446	Q8N4L1
QTHLYACGTGAFHPI	SEMA3A	126	Q14563
GRFVAICRPLHYSTF	OR5AR1	121	Q8NGP9
CGSHLTGITLFYGTV	OR5AR1	241	Q8NGP9
HLPFVGFTYTSSCVL	CDC42BPA	396	Q5VT25
AAGPSGVSVSRYHCL	KBTBD11	516	O94819
SQFVSPFTGCIYGRH	MRPS18C	81	Q9Y3D5
PFTGCIYGRHITGLC	MRPS18C	86	Q9Y3D5
TTGFCLHSAIYAARP	ADD2	206	P35612
SIRFPALEHCYTGGE	ACSM1	331	Q08AH1
VTGRAGHPVLYCSAR	NEU3	231	Q9UQ49
LISHCGPVTGYIFAL	PIGA	416	P37287
YGGPCSQSVRSVFAV	FAP	541	Q12884
EGSAHLAVPGVYFTC	UBXN6	111	Q9BZV1
FLPGSQKLVTCTGYH	WDR74	191	Q6RFH5
TYFIFGTSRHISVGP	SLC26A4	126	O43511
TVYFKCRHPTGGSFI	TBCE	56	Q15813
SGAVYRVCAGTATFH	SERINC4	116	A6NH21
HVYPTCRNTSGILGF	NRDC	961	O43847
ALFTHRCVYSGRFGS	STAB2	696	Q8WWQ8
ITASQPSHAGIYLCG	TRAV34	96	A0A0B4J273
TITFVPGLAICHYSS	TTTY12	21	Q9BZ98
RTHGIAVSPCGAYLA	GTF3C4	476	Q9UKN8
YIVFVCLPHSFTGLG	PTH2R	376	P49190
TPGSGKFCRLITYSH	nan	96	Q86TA4
DCGRRFSYPSLLVSH	ZNF689	181	Q96CS4
SPRAAGFYACHVRSL	TP53TG3	86	Q9ULZ0
VYSFSVLEPHGCGRL	WDR4	126	P57081
RPAIHSRGTYIGCFS	WSCD1	136	Q658N2
SLCFTPGYTIERHSG	UGT2B28	171	Q9BY64
SHTPERFSGTGCYGA	MID2	566	Q9UJV3
VGSCAGLFGVPISYH	TMEM177	21	Q53S58
SHLCGRVFKVGEPTY	UBR2	96	Q8IWV8
AHTYSCGSGVGIFLR	UBR2	1661	Q8IWV8
HPLFSLTSGACRLDY	TCF25	321	Q9BQ70
RKLASFTGGRYHCPV	VWA3A	1101	A6NCI4
FTGGRYHCPVGEDTL	VWA3A	1106	A6NCI4
RLYHFPCATASGSFL	KMT2D	191	O14686
FTCHGLVTGQSYIFR	MYOM1	796	P52179