Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	estrogen catabolic process	UGT1A10 UGT1A7 UGT1A9	1.59e-06	5	113	3	GO:0006711
GeneOntologyBiologicalProcess	phenylpropanoid catabolic process	UGT1A10 UGT1A7 UGT1A9	3.16e-06	6	113	3	GO:0046271
GeneOntologyBiologicalProcess	coumarin catabolic process	UGT1A10 UGT1A7 UGT1A9	3.16e-06	6	113	3	GO:0046226
GeneOntologyBiologicalProcess	flavone metabolic process	UGT1A10 UGT1A7 UGT1A9	3.16e-06	6	113	3	GO:0051552
GeneOntologyBiologicalProcess	phenylpropanoid metabolic process	UGT1A10 UGT1A7 UGT1A9	1.87e-05	10	113	3	GO:0009698
GeneOntologyBiologicalProcess	coumarin metabolic process	UGT1A10 UGT1A7 UGT1A9	1.87e-05	10	113	3	GO:0009804
GeneOntologyBiologicalProcess	flavonoid metabolic process	UGT1A10 UGT1A7 UGT1A9	4.40e-05	13	113	3	GO:0009812
Domain	ARM-type_fold	SMG1 WAPL INTS7 APC2 HUWE1 ARID1A VIRMA RANBP17 UNC45B ATM XPO7	5.15e-06	339	110	11	IPR016024
Domain	ATM/Tel1	SMG1 ATM	3.44e-05	2	110	2	IPR015519
Domain	ARM-like	SMG1 INTS7 APC2 HUWE1 ARID1A RANBP17 UNC45B XPO7	1.97e-04	270	110	8	IPR011989
Domain	ALBUMIN	GC AFP	2.05e-04	4	110	2	SM00103
Domain	Serum_albumin_N	GC AFP	2.05e-04	4	110	2	IPR014760
Domain	Serum_albumin_CS	GC AFP	2.05e-04	4	110	2	IPR020857
Domain	ALBUMIN_2	GC AFP	2.05e-04	4	110	2	PS51438
Domain	ALBUMIN_1	GC AFP	2.05e-04	4	110	2	PS00212
Domain	Serum_albumin	GC AFP	2.05e-04	4	110	2	PF00273
Domain	UDPGT	UGT1A10 UGT1A7 UGT1A9	2.45e-04	21	110	3	PF00201
Domain	UDPGT	UGT1A10 UGT1A7 UGT1A9	2.45e-04	21	110	3	PS00375
Domain	UDP_glucos_trans	UGT1A10 UGT1A7 UGT1A9	2.45e-04	21	110	3	IPR002213
Domain	Serum_albumin-like	GC AFP	3.40e-04	5	110	2	IPR020858
Domain	FATC	SMG1 ATM	3.40e-04	5	110	2	PF02260
Domain	FAT	SMG1 ATM	5.08e-04	6	110	2	PS51189
Domain	FATC	SMG1 ATM	5.08e-04	6	110	2	PS51190
Domain	FATC_dom	SMG1 ATM	5.08e-04	6	110	2	IPR003152
Domain	PIK_FAT	SMG1 ATM	5.08e-04	6	110	2	IPR014009
Domain	ALB/AFP/VDB	GC AFP	5.08e-04	6	110	2	IPR000264
Domain	FATC	SMG1 ATM	5.08e-04	6	110	2	SM01343
Pathway	KEGG_STARCH_AND_SUCROSE_METABOLISM	UGT1A10 UGT1A7 UGT1A9 G6PC2	1.57e-04	52	74	4	M14171
Pathway	KEGG_STEROID_HORMONE_BIOSYNTHESIS	UGT1A10 UGT1A7 CYP17A1 UGT1A9	1.95e-04	55	74	4	M14933
Pathway	WP_ESTROGEN_METABOLISM	UGT1A10 UGT1A7 UGT1A9	1.99e-04	22	74	3	MM15888
Pathway	REACTOME_GLUCURONIDATION	UGT1A10 UGT1A7 UGT1A9	2.60e-04	24	74	3	MM14599
Pathway	REACTOME_GLUCURONIDATION	UGT1A10 UGT1A7 UGT1A9	2.94e-04	25	74	3	M17787
Pathway	WP_GLUCURONIDATION	UGT1A10 UGT1A7 UGT1A9	2.94e-04	25	74	3	MM15820
Pathway	KEGG_ASCORBATE_AND_ALDARATE_METABOLISM	UGT1A10 UGT1A7 UGT1A9	2.94e-04	25	74	3	M605
Pathway	WP_GLUCURONIDATION	UGT1A10 UGT1A7 UGT1A9	3.31e-04	26	74	3	M39404
Pathway	KEGG_PENTOSE_AND_GLUCURONATE_INTERCONVERSIONS	UGT1A10 UGT1A7 UGT1A9	4.14e-04	28	74	3	M19580
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	SMG1 WAPL EMC1 VPS50 E2F3 ICE1 NCAPH LRCH1 IVNS1ABP KMT2C TET1 EIF2AK4 PPIP5K2	3.28e-08	529	118	13	14621295
Pubmed	Irinotecan pharmacokinetics/pharmacodynamics and UGT1A genetic polymorphisms in Japanese: roles of UGT1A16 and 28.	UGT1A10 UGT1A7 UGT1A9	1.52e-07	4	118	3	17558305
Pubmed	Circadian Clock Component Rev-erbα Regulates Diurnal Rhythm of UDP-Glucuronosyltransferase 1a9 and Drug Glucuronidation in Mice.	UGT1A10 UGT1A7 UGT1A9	7.56e-07	6	118	3	32527940
Pubmed	Use of glucuronidation fingerprinting to describe and predict mono- and dihydroxyflavone metabolism by recombinant UGT isoforms and human intestinal and liver microsomes.	UGT1A10 UGT1A7 UGT1A9	7.56e-07	6	118	3	20297805
Pubmed	Assignment of the human UDP glucuronosyltransferase gene (UGT1A1) to chromosome region 2q37.	UGT1A10 UGT1A7 UGT1A9	1.32e-06	7	118	3	8467709
Pubmed	Molecular cloning of two cDNAs encoding the mouse bilirubin/phenol family of UDP-glucuronosyltransferases (mUGTBr/p).	UGT1A10 UGT1A7 UGT1A9	1.32e-06	7	118	3	8464825
Pubmed	Cyp3a11-mediated testosterone-6β-hydroxylation decreased, while UGT1a9-mediated propofol O-glucuronidation increased, in mice with diabetes mellitus.	UGT1A10 UGT1A7 UGT1A9	1.32e-06	7	118	3	27514509
Pubmed	Alternatively spliced products of the UGT1A gene interact with the enzymatically active proteins to inhibit glucuronosyltransferase activity in vitro.	UGT1A10 UGT1A7 UGT1A9	2.11e-06	8	118	3	20610558
Pubmed	Disposition of flavonoids via enteric recycling: enzyme stability affects characterization of prunetin glucuronidation across species, organs, and UGT isoforms.	UGT1A10 UGT1A7 UGT1A9	2.11e-06	8	118	3	18052087
Pubmed	Oligomerization of the UDP-glucuronosyltransferase 1A proteins: homo- and heterodimerization analysis by fluorescence resonance energy transfer and co-immunoprecipitation.	UGT1A10 UGT1A7 UGT1A9	2.11e-06	8	118	3	17179145
Pubmed	A genome-wide association study identifies UGT1A1 as a regulator of serum cell-free DNA in young adults: The Cardiovascular Risk in Young Finns Study.	UGT1A10 UGT1A7 UGT1A9	3.15e-06	9	118	3	22511988
Pubmed	Association of SNPs in the UGT1A gene cluster with total bilirubin and mortality in the Diabetes Heart Study.	UGT1A10 UGT1A7 UGT1A9	4.49e-06	10	118	3	23642732
Pubmed	UDP-glucuronosyltransferases.	UGT1A10 UGT1A7 UGT1A9	4.49e-06	10	118	3	11465080
Pubmed	A genome-wide association study for serum bilirubin levels and gene-environment interaction in a Chinese population.	UGT1A10 UGT1A7 UGT1A9	4.49e-06	10	118	3	23371916
Pubmed	The core component of the mammalian SWI/SNF complex SMARCD3/BAF60c is a coactivator for the nuclear retinoic acid receptor.	RARB ARID1A NCOA1	4.49e-06	10	118	3	17363140
Pubmed	A genome-wide association study of total bilirubin and cholelithiasis risk in sickle cell anemia.	UGT1A10 UGT1A7 UGT1A9	4.49e-06	10	118	3	22558097
Pubmed	Role of UDP-glucuronosyltransferase isoforms in 13-cis retinoic acid metabolism in humans.	UGT1A10 UGT1A7 UGT1A9	8.19e-06	12	118	3	20308471
Pubmed	Common variants in the SLCO1B3 locus are associated with bilirubin levels and unconjugated hyperbilirubinemia.	UGT1A10 UGT1A7 UGT1A9	8.19e-06	12	118	3	19419973
Pubmed	Thirteen UDPglucuronosyltransferase genes are encoded at the human UGT1 gene complex locus.	UGT1A10 UGT1A7 UGT1A9	8.19e-06	12	118	3	11434514
Pubmed	UGT1A1 is a major locus influencing bilirubin levels in African Americans.	UGT1A10 UGT1A7 UGT1A9	1.06e-05	13	118	3	22085899
Pubmed	Genome-wide analysis of hepatic lipid content in extreme obesity.	UGT1A10 UGT1A7 UGT1A9	1.06e-05	13	118	3	25246029
Pubmed	SMG1 heterozygosity exacerbates haematopoietic cancer development in Atm null mice by increasing persistent DNA damage and oxidative stress.	SMG1 ATM	1.14e-05	2	118	2	31565865
Pubmed	hSMG-1 and ATM sequentially and independently regulate the G1 checkpoint during oxidative stress.	SMG1 ATM	1.14e-05	2	118	2	18332866
Pubmed	Genetic link of hepatocellular carcinoma with polymorphisms of the UDP-glucuronosyltransferase UGT1A7 gene.	UGT1A7 UGT1A9	1.14e-05	2	118	2	11677206
Pubmed	Novel functional polymorphisms in the UGT1A7 and UGT1A9 glucuronidating enzymes in Caucasian and African-American subjects and their impact on the metabolism of 7-ethyl-10-hydroxycamptothecin and flavopiridol anticancer drugs.	UGT1A7 UGT1A9	1.14e-05	2	118	2	12944498
Pubmed	Influence of UGT1A7 and UGT1A9 intronic I399 genetic polymorphisms on mycophenolic acid pharmacokinetics in Japanese renal transplant recipients.	UGT1A7 UGT1A9	1.14e-05	2	118	2	17529886
Pubmed	Transgenic expression of E2F3a causes DNA damage leading to ATM-dependent apoptosis.	E2F3 ATM	1.14e-05	2	118	2	18469863
Pubmed	Differences in the glucuronidation of bisphenols F and S between two homologous human UGT enzymes, 1A9 and 1A10.	UGT1A10 UGT1A9	1.14e-05	2	118	2	25547628
Pubmed	Identification of a novel putative Ran-binding protein and its close homologue.	RANBP17 XPO7	1.14e-05	2	118	2	11071879
Pubmed	TLR4, IL10RA, and NOD2 mutation in paediatric Crohn's disease patients: an association with Mycobacterium avium subspecies paratuberculosis and TLR4 and IL10RA expression.	IL10RA TLR4	1.14e-05	2	118	2	23455702
Pubmed	Changes in alpha-foetoprotein and Gc-globulin in relation to outcomes in non-acetaminophen acute liver failure.	GC AFP	1.14e-05	2	118	2	31421008
Pubmed	Basement membrane protein nidogen-1 is a target of meprin β in cisplatin nephrotoxicity.	MEP1B NID1	1.14e-05	2	118	2	25957482
Pubmed	Identification of UDP-glucuronosyltransferases responsible for the glucuronidation of darexaban, an oral factor Xa inhibitor, in human liver and intestine.	UGT1A10 UGT1A9	1.14e-05	2	118	2	22031623
Pubmed	UGT1A7 and UGT1A9 polymorphisms predict response and toxicity in colorectal cancer patients treated with capecitabine/irinotecan.	UGT1A7 UGT1A9	1.14e-05	2	118	2	15709193
Pubmed	How many and which amino acids are responsible for the large activity differences between the highly homologous UDP-glucuronosyltransferases (UGT) 1A9 and UGT1A10?	UGT1A10 UGT1A9	1.14e-05	2	118	2	20089735
Pubmed	Mayo Genome Consortia: a genotype-phenotype resource for genome-wide association studies with an application to the analysis of circulating bilirubin levels.	UGT1A10 UGT1A7 UGT1A9	1.35e-05	14	118	3	21646302
Pubmed	Human UDP-glucuronosyltransferases: metabolism, expression, and disease.	UGT1A10 UGT1A7 UGT1A9	1.35e-05	14	118	3	10836148
Pubmed	The UDP glycosyltransferase gene superfamily: recommended nomenclature update based on evolutionary divergence.	UGT1A10 UGT1A7 UGT1A9	1.35e-05	14	118	3	9295054
Pubmed	Multiple variable first exons: a mechanism for cell- and tissue-specific gene regulation.	UGT1A10 UGT1A7 UGT1A9	1.35e-05	14	118	3	14672974
Pubmed	Genome-wide association meta-analysis for total serum bilirubin levels.	UGT1A10 UGT1A7 UGT1A9	2.06e-05	16	118	3	19414484
Pubmed	Genome-wide association of serum bilirubin levels in Korean population.	UGT1A10 UGT1A7 UGT1A9	2.50e-05	17	118	3	20639394
Pubmed	Phase II metabolism of hesperetin by individual UDP-glucuronosyltransferases and sulfotransferases and rat and human tissue samples.	UGT1A10 UGT1A7 UGT1A9	2.99e-05	18	118	3	20056724
Pubmed	Comprehensive analysis of UGT1A polymorphisms predictive for pharmacokinetics and treatment outcome in patients with non-small-cell lung cancer treated with irinotecan and cisplatin.	UGT1A7 UGT1A9	3.42e-05	3	118	2	16636344
Pubmed	Glucuronidation of psilocin and 4-hydroxyindole by the human UDP-glucuronosyltransferases.	UGT1A10 UGT1A9	3.42e-05	3	118	2	20007669
Pubmed	Stress-induced phosphorylation and proteasomal degradation of mitofusin 2 facilitates mitochondrial fragmentation and apoptosis.	HUWE1 MFN2	3.42e-05	3	118	2	22748923
Pubmed	Genetic linkage of UGT1A7 and UGT1A9 polymorphisms to UGT1A1*6 is associated with reduced activity for SN-38 in Japanese patients with cancer.	UGT1A7 UGT1A9	3.42e-05	3	118	2	17406868
Pubmed	Identification of RANBP16 and RANBP17 as novel interaction partners for the bHLH transcription factor E12.	RANBP17 XPO7	3.42e-05	3	118	2	20503194
Pubmed	Linkage between vitamin D-binding protein and alpha-fetoprotein in the mouse.	GC AFP	3.42e-05	3	118	2	8835525
Pubmed	Cloning and characterization of the human UDP-glucuronosyltransferase 1A8, 1A9, and 1A10 gene promoters: differential regulation through an interior-like region.	UGT1A10 UGT1A9	3.42e-05	3	118	2	12847094
Pubmed	TLR4 knockout upregulates the expression of Mfn2 and PGC-1α in a high-fat diet and ischemia-reperfusion mice model of liver injury.	TLR4 MFN2	3.42e-05	3	118	2	32437795
Pubmed	Predictive role of the UGT1A1, UGT1A7, and UGT1A9 genetic variants and their haplotypes on the outcome of metastatic colorectal cancer patients treated with fluorouracil, leucovorin, and irinotecan.	UGT1A7 UGT1A9	3.42e-05	3	118	2	19364970
Pubmed	Amphiphysin (Amph) maps to the proximal region of mouse chromosome 13.	BTN1A1 NID1	3.42e-05	3	118	2	8530056
Pubmed	Cooperative Regulation of Intestinal UDP-Glucuronosyltransferases 1A8, -1A9, and 1A10 by CDX2 and HNF4α Is Mediated by a Novel Composite Regulatory Element.	UGT1A10 UGT1A9	3.42e-05	3	118	2	29519853
Pubmed	Differences in UGT1A1, UGT1A7, and UGT1A9 polymorphisms between Uzbek and Japanese populations.	UGT1A7 UGT1A9	3.42e-05	3	118	2	24453052
Pubmed	[Influence of genetic polymorphisms in UGT1A1, UGT1A7 and UGT1A9 on the pharmacokynetics of irinotecan, SN-38 and SN-38G].	UGT1A7 UGT1A9	3.42e-05	3	118	2	23789755
Pubmed	The ATM-related kinase, hSMG-1, bridges genome and RNA surveillance pathways.	SMG1 ATM	3.42e-05	3	118	2	15279777
Pubmed	A genome-wide assessment of variability in human serum metabolism.	UGT1A10 UGT1A7 UGT1A9	3.55e-05	19	118	3	23281178
Pubmed	CDK4/6-dependent activation of DUB3 regulates cancer metastasis through SNAIL1.	USP17L2 ATM USP17L8	3.55e-05	19	118	3	28067227
Pubmed	Genome-wide CRISPR Screen to Identify Genes that Suppress Transformation in the Presence of Endogenous KrasG12D.	LRRC8C KANSL2 ATM	6.42e-05	23	118	3	31748650
Pubmed	Retinoic acid signalling induces the differentiation of mouse fetal liver-derived hepatic progenitor cells.	RARB AFP NCOA1	6.42e-05	23	118	3	19737349
Pubmed	Cancer gene mutation frequencies for the U.S. population.	ARID1A KMT2C	6.82e-05	4	118	2	34645806
Pubmed	Molecular cloning and properties of a full-length putative thyroid hormone receptor coactivator.	RARB NCOA1	6.82e-05	4	118	2	8754792
Pubmed	ATM and SIRT6/SNF2H Mediate Transient H2AX Stabilization When DSBs Form by Blocking HUWE1 to Allow Efficient γH2AX Foci Formation.	HUWE1 ATM	6.82e-05	4	118	2	26711340
Pubmed	Differential expression of the UGT1A locus in human liver, biliary, and gastric tissue: identification of UGT1A7 and UGT1A10 transcripts in extrahepatic tissue.	UGT1A10 UGT1A7	6.82e-05	4	118	2	9271343
Pubmed	Chromosomal mapping of a human phenol UDP-glucuronosyltransferase, GNT1.	UGT1A10 UGT1A9	6.82e-05	4	118	2	2108603
Pubmed	The mRNA surveillance protein hSMG-1 functions in genotoxic stress response pathways in mammalian cells.	SMG1 ATM	6.82e-05	4	118	2	15175154
Pubmed	UGT1A and TYMS genetic variants predict toxicity and response of colorectal cancer patients treated with first-line irinotecan and fluorouracil combination therapy.	UGT1A7 UGT1A9	6.82e-05	4	118	2	20628391
Pubmed	Ablation of steroid receptor coactivator-3 resembles the human CACT metabolic myopathy.	SLC25A20 NCOA1	6.82e-05	4	118	2	22560224
Pubmed	The E3 ubiquitin ligase Mule acts through the ATM-p53 axis to maintain B lymphocyte homeostasis.	HUWE1 ATM	6.82e-05	4	118	2	22213803
Pubmed	Genetic determinants influencing human serum metabolome among African Americans.	UGT1A10 UGT1A7 UGT1A9	7.31e-05	24	118	3	24625756
Pubmed	Pharmacokinetics of mycophenolate mofetil and its glucuronide metabolites in healthy volunteers.	UGT1A7 UGT1A9	1.13e-04	5	118	2	18597651
Pubmed	Lack of association between UGT1A7, UGT1A9, ARP, SPINK1 and CFTR gene polymorphisms and pancreatic cancer in Italian patients.	UGT1A7 UGT1A9	1.13e-04	5	118	2	17072959
Pubmed	Risk of diarrhoea in a long-term cohort of renal transplant patients given mycophenolate mofetil: the significant role of the UGT1A8 2 variant allele.	UGT1A7 UGT1A9	1.13e-04	5	118	2	20565459
Pubmed	Variation of hepatic glucuronidation: Novel functional polymorphisms of the UDP-glucuronosyltransferase UGT1A4.	UGT1A10 UGT1A9	1.13e-04	5	118	2	15057901
Pubmed	The major chemical-detoxifying system of UDP-glucuronosyltransferases requires regulated phosphorylation supported by protein kinase C.	UGT1A10 UGT1A7	1.13e-04	5	118	2	18556656
Pubmed	Regulation of Active DNA Demethylation through RAR-Mediated Recruitment of a TET/TDG Complex.	RARB TET1	1.13e-04	5	118	2	28538185
Pubmed	Liver-specific T regulatory type-1 cells program local neutrophils to suppress hepatic autoimmunity via CRAMP.	IL10RA G6PC2	1.70e-04	6	118	2	33789099
Pubmed	Mutant IDH1 Downregulates ATM and Alters DNA Repair and Sensitivity to DNA Damage Independent of TET2.	TET1 ATM	1.70e-04	6	118	2	27424808
Pubmed	Redefining the concept of protease-activated receptors: cathepsin S evokes itch via activation of Mrgprs.	MRGPRX1 CTSS	1.70e-04	6	118	2	26216096
Pubmed	Analysis of inherited genetic variations at the UGT1 locus in the French-Canadian population.	UGT1A7 UGT1A9	1.70e-04	6	118	2	19204906
Pubmed	HIV-1 Tat protein induces PD-L1 (B7-H1) expression on dendritic cells through tumor necrosis factor alpha- and toll-like receptor 4-mediated mechanisms.	CD83 TLR4	1.70e-04	6	118	2	24696476
Pubmed	Suppression of C/EBP alpha expression in biliary cell differentiation from hepatoblasts during mouse liver development.	AFP NID1	1.70e-04	6	118	2	15519652
Pubmed	Isotype-restricted corepressor recruitment: a constitutively closed helix 12 conformation in retinoic acid receptors beta and gamma interferes with corepressor recruitment and prevents transcriptional repression.	RARB NCOA1	2.37e-04	7	118	2	12665583
Pubmed	Gene polymorphisms in Toll-like receptors, interleukin-10, and interleukin-10 receptor alpha and lymphoma risk.	IL10RA TLR4	2.37e-04	7	118	2	16971956
Pubmed	Cloning and expression analysis of the mouse stroma marker Snep encoding a novel nidogen domain protein.	RARB NID1	2.37e-04	7	118	2	15162516
Pubmed	Endothelial Cyp26b1 restrains murine heart valve growth during development.	RARB LAMP2 BMP3 ART4 NID1	2.43e-04	163	118	5	35364055
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	WAPL VPS50 GC KMT2C NID1 EIF2AK4 ATM IGKV4-1	3.05e-04	497	118	8	36774506
Pubmed	A genetic screen identifies the Triple T complex required for DNA damage signaling and ATM and ATR stability.	SMG1 ATM	3.15e-04	8	118	2	20810650
Pubmed	Asparagine endopeptidase controls anti-influenza virus immune responses through TLR7 activation.	TLR4 CTSS	3.15e-04	8	118	2	22916010
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	USP45 WAPL CYP17A1 HUWE1 KMT2C ATRNL1 TET1 TLR4 SERINC3 EIF2AK4 CKAP2 VPS13B	3.26e-04	1084	118	12	11544199
Pubmed	HIV-1 Nef and Vpu are functionally redundant broad-spectrum modulators of cell surface receptors, including tetraspanins.	LAMP2 CD83 CD37	3.43e-04	40	118	3	25275127
Pubmed	Family-based genome-wide association scan of attention-deficit/hyperactivity disorder.	UGT1A10 UGT1A9	4.05e-04	9	118	2	20732626
Pubmed	Deregulated E2f-2 underlies cell cycle and maturation defects in retinoblastoma null erythroblasts.	E2F3 ATM	4.05e-04	9	118	2	17923680
Pubmed	Ubiquitin Linkage-Specific Affimers Reveal Insights into K6-Linked Ubiquitin Signaling.	HUWE1 MFN2	4.05e-04	9	118	2	28943312
Pubmed	Cleavage of nidogen-1 by cathepsin S impairs its binding to basement membrane partners.	NID1 CTSS	4.05e-04	9	118	2	22952693
Pubmed	Identification of two novel RanGTP-binding proteins belonging to the importin beta superfamily.	RANBP17 XPO7	4.05e-04	9	118	2	11024021
Pubmed	Identification of the ligands of protein interaction domains through a functional approach.	RABGAP1 EPS8L3	4.05e-04	9	118	2	17124247
Pubmed	Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	SYNE1 TET1 ZFHX2 SENP7	4.14e-04	102	118	4	11214970
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	WAPL RARB SYNE1 APC2 E2F3 HUWE1 ARID1A KANSL2 ATRNL1 KCNN1 SYT4 ATM CKAP2	4.31e-04	1285	118	13	35914814
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	MYO10 SYNE1 VIRMA MFN2 VPS13B SENP7 XPO7	4.94e-04	407	118	7	12693553
Cytoband	2q37	UGT1A10 UGT1A7 UGT1A9	7.06e-05	31	118	3	2q37
GeneFamily	UDP glucuronosyltransferases	UGT1A10 UGT1A7 UGT1A9	2.76e-04	32	72	3	363
ToppCell	droplet-Liver-LIVER_HEP-30m-Myeloid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL10RA SLC25A36 DMRT2 GVINP1 SYT4 CTSS	6.30e-06	172	117	6	3f784aed340b50ddbec3f7dc0a5279180d38a2bb
ToppCell	facs-Marrow-B-cells-24m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD83 SORCS1 CD37 G6PC2 USH2A CTSS	6.95e-06	175	117	6	887e75fc90e59a6394d62f3c048a9cfdf6707725
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CCNJL IARS1 MEP1B RANBP17 LIPH FDFT1	8.43e-06	181	117	6	576da14ab3107f89e1f44a4a439d1bef5bb42370
ToppCell	facs-Aorta-Heart-3m-Endothelial-nan\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO10 GC ADGRL4 UNC45B SERINC3 G6PC2	1.01e-05	187	117	6	df0279b7e94e26f5541b0e2a0ce56befa96ec8ca
ToppCell	LPS-IL1RA+antiTNF-Myeloid\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	IL10RA NAIP CD83 CD37 TLR4 CTSS	1.01e-05	187	117	6	4e0bbef6ba0d1b3e1f8d900d4a9dbd41f09a7bc5
ToppCell	facs-Aorta-Heart-3m\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRRC8C SYNE1 NEDD1 LRCH1 IVNS1ABP SERINC3	1.18e-05	192	117	6	1ccc47792edf9ee23501c8e2165d11271636b66a
ToppCell	Smart-start-Cell-Wel_seq-Neoplastic-Stem-like-OPC-like-OPC-like-F\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CDC20B ANKRD30B GC AFP ZNF804B USH2A	1.21e-05	193	117	6	315840bc48899f3a36d57b19197509de19716e3d
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DCDC1 SYNE1 BBS5 WDR93 HHLA2 ZFHX2	1.36e-05	197	117	6	74a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCell	BL\|World / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	IL10RA NAIP E2F3 IVNS1ABP CD37 TLR4	1.36e-05	197	117	6	1acf0191fa0a25cd20bfd9ea7bf727a1555986a1
ToppCell	facs-Tongue-nan-3m-Epithelial-nan\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SMG1 LAMP2 HUWE1 LRCH1 IVNS1ABP SERINC3	1.44e-05	199	117	6	8d50e1ee58710d896c0204937331d9f4dcd38de0
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW13-Stem_cells\|GW13 / Sample Type, Dataset, Time_group, and Cell type.	NEDD1 ARID1A NCAPH IVNS1ABP NID1 CKAP2	1.44e-05	199	117	6	fd1d1b95e01719e3d0a17d9d1f29717a47209d32
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW13-Stem_cells-Stem_cells\|GW13 / Sample Type, Dataset, Time_group, and Cell type.	NEDD1 ARID1A NCAPH IVNS1ABP NID1 CKAP2	1.44e-05	199	117	6	91882af9dc7265c9b419f4415cbcf656087a2ab3
ToppCell	E16.5-samps-Myeloid-Macrophage\|E16.5-samps / Age Group, Lineage, Cell class and subclass	UGT1A10 UGT1A9 CD83 CD37 TLR4	4.48e-05	148	117	5	cd5f697d8c2f272be1f3f52a05446749278431c5
ToppCell	E16.5-samps-Myeloid-Macrophage-CD163+_Macrophage\|E16.5-samps / Age Group, Lineage, Cell class and subclass	UGT1A10 UGT1A9 CD83 CD37 TLR4	4.48e-05	148	117	5	56e146980a71b5ca655118ae13310c5949220d4a
ToppCell	E16.5-samps-Myeloid\|E16.5-samps / Age Group, Lineage, Cell class and subclass	IL10RA UGT1A10 GVINP1 CD37 CTSS	5.76e-05	156	117	5	c7c73cef5700b0ae75280e62c94728434c712537
ToppCell	droplet-Thymus-nan-3m-Myeloid-B_cell\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD83 SORCS1 LIPH NID1 CTSS	7.73e-05	166	117	5	c0af93db981dfd448abc7efcd257f3e5ff066aae
ToppCell	343B-Lymphocytic-ILC\|343B / Donor, Lineage, Cell class and subclass (all cells)	INTS6L IL10RA VPS50 ZSCAN32 TET1	7.73e-05	166	117	5	a54377c703efff42d2cc1a8fdb610facc58053dd
ToppCell	droplet-Marrow-BM-1m-Myeloid-basophil\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL10RA LRRC8C INTS7 RANBP17 GVINP1	8.18e-05	168	117	5	2e88d9cb7c80a4656fab290db8b45a5a0599d769
ToppCell	PND28-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_prolif\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SLC35C1 E2F3 GVINP1 ZFHX2 CTSS	8.18e-05	168	117	5	27cdf5cfa1d906868cfd60fdfab3cd51f3b3602f
ToppCell	droplet-Thymus-nan-21m-Myeloid-B_cell\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD83 DMRT2 CD37 NID1 CTSS	8.89e-05	171	117	5	8bed33f61f7d12a1ac4fba33f730d839f5ee7bef
ToppCell	E16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_G2M\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KCTD19 RASL12 TRAM1L1 NID1 CKAP2	9.91e-05	175	117	5	fa16c6ba08dc0cc22e8cf049db0577811d080df6
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD83 CD37 G6PC2 USH2A CTSS	1.02e-04	176	117	5	c6484334187f64cd00cd35e77d8ae436556b4260
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Endothelial\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRRC8C MYO10 ADGRL4 GVINP1 UNC45B	1.05e-04	177	117	5	ca5a30b3e7bcfdd8de01ceaf7449735b5cd503af
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Endothelial-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRRC8C MYO10 ADGRL4 GVINP1 UNC45B	1.05e-04	177	117	5	f471f7747d6e8db7546899019af9508f48a14f89
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Endothelial-endothelial_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRRC8C MYO10 ADGRL4 GVINP1 UNC45B	1.05e-04	177	117	5	cd0684b876c2a7d5fe7e2773e8e25bb61ecbc795
ToppCell	droplet-Heart-4Chambers-18m-Endothelial-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRRC8C MYO10 ADGRL4 UNC45B SYT4	1.07e-04	178	117	5	ba2f0585626988b511046630bc16be5c5fec3fb2
ToppCell	droplet-Limb_Muscle-MUSCLE-30m\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WAPL MYO10 SYNE1 ADGRL4 GVINP1	1.07e-04	178	117	5	01dafd19de04eff459253eaa9a35debf8f3deedf
ToppCell	3'-GW_trimst-2-LargeIntestine-Hematopoietic-Myeloid-Macrophages\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	IL10RA NAIP CD83 TLR4 CTSS	1.10e-04	179	117	5	409364d916c5e7e2291284cc74351d8f8a8447ac
ToppCell	Control-Myeloid-Monocytes,_Macrophages\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	IL10RA NAIP CD83 CD37 TLR4	1.10e-04	179	117	5	a79a244bf8ecc333d034b2eb2de554d3310ca6de
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6-Exc_L6_THEMIS_LINC00343\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	NPTX1 ANKRD30B SORCS1 ZNF804B SYT4	1.10e-04	179	117	5	065a50952e8703fa07767beb6b73a090bf378ca6
ToppCell	Control-Myeloid-Monocytes,_Macrophages-Monocytes-Macrophages\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	IL10RA NAIP CD83 CD37 TLR4	1.10e-04	179	117	5	c4ff8b191ed0f6dc2dd784869f6f2c62e170a7db
ToppCell	droplet-Liver-hepatocytes-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RARB MYO10 ADGRL4 UNC45B ATRNL1	1.16e-04	181	117	5	4df7972f88117108698efd06b124b232f8588981
ToppCell	Control-Myeloid\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	IL10RA NAIP CD83 CD37 TLR4	1.16e-04	181	117	5	25170e5285996cc80337d5f86a0255569861ae77
ToppCell	droplet-Liver-hepatocytes-3m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RARB MYO10 ADGRL4 UNC45B ATRNL1	1.16e-04	181	117	5	cbb530566893281289026bfd93adf721decd4ca3
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	NPTX1 ANKRD30B GRM2 ADGRL4 ZNF804B	1.19e-04	182	117	5	205d9ad1ea4b7adee8054496cdde46c9c401a19a
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	NPTX1 ANKRD30B SORCS1 ZNF804B SYT4	1.19e-04	182	117	5	31efc06d6b073e8e341648207093e5f33c6f9183
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NLRP11 GC AFP SLC47A1 USH2A	1.22e-04	183	117	5	d73cac83cde82665f110baad7cf28db75f9ffe52
ToppCell	3'-Child04-06-SmallIntestine-Hematopoietic-Myeloid-Lymphoid_DC\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NPTX1 CD83 NEDD1 KCNN1 ZFHX2	1.29e-04	185	117	5	48de4d9fad55077732bf64eca4919103ecbc1512
ToppCell	LPS-antiTNF-Myeloid\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	IL10RA CD83 CD37 TLR4 CTSS	1.32e-04	186	117	5	839c6da5244f469461b2e5563e36162b2911cd01
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Hematopoietic-Myeloid\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	IL10RA NAIP CD37 TLR4 CTSS	1.32e-04	186	117	5	c0a58e43a813441d3a1708236737b15db8bea10e
ToppCell	TCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1\|TCGA-Pancreas / Sample_Type by Project: Shred V9	SMG1 WAPL RABGAP1 LRCH1 VPS13B	1.32e-04	186	117	5	03db813598b67b1e08f759758a1c2023396921fa
ToppCell	facs-Heart-LV-3m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRRC8C MYO10 ADGRL4 UNC45B SERINC3	1.35e-04	187	117	5	1bc338c22d645a854f8d8eb8a064c441121fb673
ToppCell	facs-Spleen-nan-3m-Lymphocytic-CD79a_B_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL10RA GC CD37 SERINC3 CTSS	1.35e-04	187	117	5	b51af2824e65734f333b1325117f4a2e88b17c23
ToppCell	facs-Pancreas-Endocrine-3m-Endothelial\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRRC8C RASL12 ADGRL4 UNC45B NID1	1.39e-04	188	117	5	da862ea3c74f42d0dbae38b09211a45c593d477e
ToppCell	facs-Marrow-T-cells-3m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD83 CD37 NID1 SERINC3 CTSS	1.39e-04	188	117	5	1f07e3ab87173426fe0c429f5c084fb3425effd3
ToppCell	facs-Marrow-T-cells-3m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD83 CD37 NID1 SERINC3 CTSS	1.39e-04	188	117	5	85746f95319e494efdc1bbc24331698688d3a900
ToppCell	5'-GW_trimst-2-LargeIntestine-Hematopoietic-Myeloid-LYVE1+_Macrophage\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	IL10RA NAIP CD83 TLR4 CTSS	1.39e-04	188	117	5	cb091912f9b627a78a8793a37df7f1de839f887f
ToppCell	facs-Pancreas-Endocrine-3m-Endothelial-nan\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRRC8C RASL12 ADGRL4 UNC45B NID1	1.39e-04	188	117	5	b82a7667ef74a05e8bc744f6c090a7cc7b8efe32
ToppCell	facs-Pancreas-Endocrine-3m-Endothelial-endothelial_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRRC8C RASL12 ADGRL4 UNC45B NID1	1.39e-04	188	117	5	19672d284fe89c9c3c7697514ca1f659329c34f4
ToppCell	343B-Lymphocytic-ILC\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	INTS6L VPS50 ZSCAN32 LIPH TET1	1.42e-04	189	117	5	c26428871dc3261327d89cacaba6e21e004ff1f3
ToppCell	droplet-Limb_Muscle-nan-21m-Endothelial-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRRC8C MYO10 ADGRL4 UNC45B SERINC3	1.46e-04	190	117	5	1ff2295c9fc94ea21fff286706b739d0deb032d0
ToppCell	droplet-Limb_Muscle-nan-21m-Endothelial-endothelial_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRRC8C MYO10 ADGRL4 UNC45B SERINC3	1.46e-04	190	117	5	61f2f9fb4b8f47a2a669f6b052214d2ce0c194cd
ToppCell	facs-Heart-LA-24m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT32 MYO10 ADGRL4 UNC45B G6PC2	1.46e-04	190	117	5	911b93c4c828ef2d867b91a5eced2dc12a1baf27
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb-3m-Endothelial-endothelial_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRRC8C MYO10 ADGRL4 UNC45B SERINC3	1.46e-04	190	117	5	38a815abf0ac5cac6071737cadc54a514f62d37d
ToppCell	droplet-Limb_Muscle-nan-21m-Endothelial\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRRC8C MYO10 ADGRL4 UNC45B SERINC3	1.46e-04	190	117	5	d415c8f3d69a8142e95307aeabc6d0e812cd5165
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb-3m-Endothelial\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRRC8C MYO10 ADGRL4 UNC45B SERINC3	1.46e-04	190	117	5	bb1476b44dd49e1dd52a636a91c4600b6d4fbe2e
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb-3m-Endothelial-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRRC8C MYO10 ADGRL4 UNC45B SERINC3	1.46e-04	190	117	5	d180205c70b5ca9bc5a01a2e6cb42fcebc7f630d
ToppCell	facs-Diaphragm-Limb_Muscle-3m-Endothelial-nan\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRRC8C MYO10 ADGRL4 UNC45B SERINC3	1.53e-04	192	117	5	8f20d3511dcb44445592b17d005a53da0052ae56
ToppCell	facs-Diaphragm-Limb_Muscle-3m-Endothelial-endothelial_cell\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRRC8C MYO10 ADGRL4 UNC45B SERINC3	1.53e-04	192	117	5	0986b7900021efe2a4df84a935e7c9a0af1b0e57
ToppCell	343B-Lymphocytic-ILC-ILC-1\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	INTS6L VPS50 ZSCAN32 LIPH TET1	1.53e-04	192	117	5	445985fe1bcd33e4f0a1704b27988fbfc9334538
ToppCell	facs-Diaphragm-Limb_Muscle-3m-Endothelial\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRRC8C MYO10 ADGRL4 UNC45B SERINC3	1.53e-04	192	117	5	b28d294e42b303d1db6060231d84d7b9e4d9fccf
ToppCell	Tracheal-10x5prime-Immune_Lymphocytic-B-B_plasma-B_plasma_IgG\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	NLRP11 IL10RA CD83 CD37 IGKV4-1	1.60e-04	194	117	5	a4a70369541876e1192df8828b63e3d1746ae3d9
ToppCell	3'-Distal_airway-Immune_Myeloid-Myeloid_monocytic\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	IL10RA NAIP CD37 TLR4 CTSS	1.64e-04	195	117	5	01da7115e38c280fb0baff2032b62bdb609bad5e
ToppCell	3'-GW_trimst-2-SmallIntestine-Hematopoietic-Myeloid-LYVE1+_Macrophage\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	IL10RA NAIP CD83 TLR4 CTSS	1.64e-04	195	117	5	028622b234551b185977fbee10c06851a45456a5
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO10 HUWE1 KMT2C NCOA1 G6PC2	1.64e-04	195	117	5	7796ea9247f4c63762f0de8490fed08b9717fa23
ToppCell	CV-Moderate-6\|Moderate / Virus stimulation, Condition and Cluster	SMG1 HUWE1 KMT2C NCOA1 CTSS	1.64e-04	195	117	5	2b8a72d7e755b9655c7a496000d10ff06e50862b
ToppCell	control-Myeloid-Non-resident_Macrophage\|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	IL10RA CD83 CD37 TLR4 NID1	1.68e-04	196	117	5	646a8d47dddffdfd2d8a62245ea6cd49f9510a1a
ToppCell	CV-Moderate-6\|CV / Virus stimulation, Condition and Cluster	SMG1 HUWE1 KMT2C NCOA1 CTSS	1.68e-04	196	117	5	7bced0cc2112697593c478fa291b8ed3941fb811
ToppCell	Bronchial-NucSeq-Epithelial-Epi_airway_neuro-secretory-Neuroendocrine\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	NLRP11 NPTX1 ATRNL1 PCBP4 USH2A	1.68e-04	196	117	5	4bdc304c0c9d8bebe1a6a8a27e44acd1e8113725
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CYP17A1 GC AFP ZNF804B SLC47A1	1.68e-04	196	117	5	4ebcaac758ed01d918de9c1cd383a84457b615f3
ToppCell	moderate-Myeloid\|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	NAIP CD83 IVNS1ABP TLR4 CTSS	1.68e-04	196	117	5	76a4c615ea7594e99c1a938d6900a1b262cc09f5
ToppCell	BL-critical-LOC-Myeloid\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	NAIP CD83 IVNS1ABP TLR4 CTSS	1.72e-04	197	117	5	932a7fae4979b561688e6222505df0f4e510ab11
ToppCell	3'-GW_trimst-2-SmallIntestine-Hematopoietic-Myeloid\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	IL10RA NAIP CD83 TLR4 CTSS	1.72e-04	197	117	5	09a2c0c0f9c2442743414236c2d5c1f27be66e4c
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Hematopoietic-Myeloid-LYVE1+_Macrophage\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	IL10RA NAIP CD37 TLR4 CTSS	1.72e-04	197	117	5	1c0024049db2d2c817a7f503de235b9630b24e33
ToppCell	3'-Broncho-tracheal-Immune_Myeloid-Myeloid_monocytic-classical_monocyte-Classical_monocytes-Classical_monocytes_L.1.2.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NAIP CD83 IVNS1ABP TLR4 CTSS	1.72e-04	197	117	5	0c059476a8cdc6ac71a01d9c414295177f45f8de
ToppCell	facs-Tongue-nan-3m-Epithelial\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SMG1 LAMP2 HUWE1 IVNS1ABP SERINC3	1.76e-04	198	117	5	2f03f8897dd7cce6d8296638e14e11ec16bcf624
ToppCell	5'-GW_trimst-2-SmallIntestine-Hematopoietic-Myeloid\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	IL10RA NAIP CD83 TLR4 CTSS	1.76e-04	198	117	5	dbae6a58cb3ce8612755fbdba6194b70b35f258a
ToppCell	5'-GW_trimst-2-SmallIntestine-Hematopoietic-Myeloid-LYVE1+_Macrophage\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	IL10RA NAIP CD83 TLR4 CTSS	1.76e-04	198	117	5	acb84681569651447d684aa3960f0510d7ff17e8
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Hematopoietic-Myeloid\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	IL10RA NAIP CD37 TLR4 CTSS	1.76e-04	198	117	5	79c8ab15e73f727c5e110ab9eab3ccb5edf9f714
ToppCell	Control_saline-Hematopoietic_Myeloid-Monocytes,_Macrophages\|Control_saline / Treatment groups by lineage, cell group, cell type	NAIP CD83 CD37 TLR4 CTSS	1.76e-04	198	117	5	684f2dd5db889f118b5218ee23733cc1361272c2
ToppCell	Tracheal-10x5prime-Immune_Myeloid-Monocytic-Monocyte_CD14\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	IL10RA NAIP CD83 CD37 CTSS	1.76e-04	198	117	5	4ba72ba1f0cebc93053aae72d763c33e155b6fa4
ToppCell	Control_saline-Hematopoietic_Myeloid-Monocytes,_Macrophages-Monocytes-Macrophages\|Control_saline / Treatment groups by lineage, cell group, cell type	NAIP CD83 CD37 TLR4 CTSS	1.76e-04	198	117	5	c15ab0660a6de445a83396cf70860ea39868914d
ToppCell	facs-Tongue-nan-3m\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SMG1 LAMP2 HUWE1 IVNS1ABP SERINC3	1.76e-04	198	117	5	f2a4057f038ef7225a5b98a7ab068c30dff4eadd
ToppCell	Kidney-Leukocytes\|Kidney / Skin and Kidney Cells in Lupus Nephritis Patients.	IL10RA CD83 CD37 IGKV4-1 CTSS	1.76e-04	198	117	5	4050553f292ce00d547bc79207d6b9a44f4db34f
ToppCell	Non-neuronal-Postmitotic\|World / Primary Cells by Cluster	CD83 ADGRL4 CD37 TLR4 CTSS	1.81e-04	199	117	5	f6a9119ad32d9f0173c432de353b5315a7cf01ad
ToppCell	5'-GW_trimst-2-SmallIntestine-Hematopoietic-Myeloid-Macrophages\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	IL10RA NAIP CD83 TLR4 CTSS	1.81e-04	199	117	5	9df2c79904dacf029ec9df1f1cde72d871189a82
ToppCell	Control_saline-Hematopoietic_Myeloid\|Control_saline / Treatment groups by lineage, cell group, cell type	NAIP CD83 CD37 TLR4 CTSS	1.81e-04	199	117	5	6be92062cce049a4c98f7311f2500bf1468fc267
ToppCell	wk_20-22-Hematologic-Myeloid\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	IL10RA NAIP CD83 TLR4 CTSS	1.81e-04	199	117	5	0740166c51ce63edf83c4b98fce057f1440116d7
ToppCell	wk_08-11-Hematologic\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	IL10RA NAIP CD37 TLR4 CTSS	1.81e-04	199	117	5	edc9afd7be8543cb93a2bb874a14aad0417dfa92
ToppCell	wk_20-22-Hematologic\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	IL10RA NAIP CD83 TLR4 CTSS	1.81e-04	199	117	5	f360c75e169536578550bed79461a5947e2472b1
ToppCell	wk_15-18-Hematologic-Myeloid-SPP1+_Mac\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	IL10RA NAIP CD83 TLR4 CTSS	1.81e-04	199	117	5	c7fc2ac1601346aac71e7620a8a440fde8d92dbd
ToppCell	wk_08-11-Hematologic-Myeloid-SPP1+_Mac\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	IL10RA NAIP CD37 TLR4 CTSS	1.81e-04	199	117	5	d94cf750599366061066074e8007d707adf6fc5a
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW13-Stem_cells\|GW13 / Sample Type, Dataset, Time_group, and Cell type.	NEDD1 ARID1A NCAPH NID1 CKAP2	1.85e-04	200	117	5	d933978b55fefe52cad599b36f6b47a0c7f71f96
ToppCell	Parenchyma_COVID-19-Immune-TX-MoAM-2\|Parenchyma_COVID-19 / Sample group, Lineage and Cell type	IL10RA NAIP CD37 TLR4 CTSS	1.85e-04	200	117	5	33c5615cbedb9e14f4433169babd3a3a51f69b4c
ToppCell	Lung_Parenchyma-Severe-Myeloid-MoAM-MoAM\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	IL10RA CD83 CD37 TLR4 CTSS	1.85e-04	200	117	5	baef622b82b262609cf5410f701ac814c20c3557
ToppCell	Tracheal-10x5prime-Immune_Myeloid\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	IL10RA NAIP CD83 CD37 CTSS	1.85e-04	200	117	5	fc6aebc20ecaa67606154540a691242dc0aea867
ToppCell	Lung_Parenchyma-Severe-Myeloid-MoAM-MoAM-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	IL10RA CD83 CD37 TLR4 CTSS	1.85e-04	200	117	5	2e7478ddb2f09b0a14635759033c2e675b981c9f
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW26-Mesenchymal-BMP_responsible_cell\|GW26 / Sample Type, Dataset, Time_group, and Cell type.	IL10RA CD83 CD37 TLR4 CTSS	1.85e-04	200	117	5	cd0d69f973ca3204b500d12031b403a1f4593431
ToppCell	Parenchyma_COVID-19-Immune-TX\|Parenchyma_COVID-19 / Sample group, Lineage and Cell type	IL10RA CD83 CD37 TLR4 CTSS	1.85e-04	200	117	5	fe27d56a05151049a64e35db5a144ff7952e6902
ToppCell	Tracheal-10x5prime-Immune_Myeloid-Monocytic\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	IL10RA NAIP CD83 CD37 CTSS	1.85e-04	200	117	5	7076b0db66c8f90c8f9ccfbc8bc0dcc82b15e5f3
Drug	naringenin chalcone	UGT1A10 UGT1A7 UGT1A9	1.28e-06	5	116	3	ctd:C027329
Drug	anthrarobin	UGT1A10 UGT1A7 UGT1A9	1.28e-06	5	116	3	ctd:C032186
Drug	1,2,5,8-tetrahydroxy anthraquinone	UGT1A10 UGT1A7 UGT1A9	2.55e-06	6	116	3	ctd:C543211
Drug	alloin	UGT1A10 UGT1A7 UGT1A9	2.55e-06	6	116	3	ctd:C006457
Drug	2',5'-dihydroxychalcone	UGT1A10 UGT1A7 UGT1A9	2.55e-06	6	116	3	ctd:C107497
Drug	N-methylpiperazine	UGT1A10 SYNE1 UGT1A7 UGT1A9	4.36e-06	22	116	4	CID000053167
Drug	2',4'-dihydroxychalcone	UGT1A10 UGT1A7 UGT1A9	4.44e-06	7	116	3	ctd:C059354
Drug	1,4-dihydroxyanthraquinone	UGT1A10 UGT1A7 UGT1A9	7.08e-06	8	116	3	ctd:C034890
Drug	Equol	UGT1A10 UGT1A7 CYP17A1 UGT1A9 AFP	8.16e-06	54	116	5	ctd:D060754
Drug	Scopoletin	UGT1A10 UGT1A7 UGT1A9 TLR4	1.03e-05	27	116	4	ctd:D012603
Drug	AC1MRQNQ	UGT1A10 UGT1A7 UGT1A9	1.06e-05	9	116	3	CID003522271
Drug	DHPASiU	UGT1A10 UGT1A7 UGT1A9	1.06e-05	9	116	3	CID000197602
Drug	3-iodophenol	UGT1A10 UGT1A7 UGT1A9	1.06e-05	9	116	3	CID000012272
Drug	AC1L4J7U	UGT1A10 UGT1A7 UGT1A9	1.06e-05	9	116	3	CID000186631
Drug	Chebi:32663	UGT1A10 UGT1A7 UGT1A9	1.06e-05	9	116	3	CID005460873
Drug	2,6-dihydroxyanthraquinone	UGT1A10 UGT1A7 UGT1A9	1.51e-05	10	116	3	ctd:C034889
Drug	paricalcitol	UGT1A10 UGT1A7 UGT1A9 GC	1.58e-05	30	116	4	CID005281104
Drug	dihydroartemisinin	UGT1A10 UGT1A7 UGT1A9 ATM	1.58e-05	30	116	4	CID000107770
Drug	fluconazole	UGT1A10 IARS1 UGT1A7 CYP17A1 UGT1A9 FDFT1	1.83e-05	107	116	6	CID000003365
Drug	Muracein C	UGT1A10 UGT1A7 UGT1A9 AFP	2.06e-05	32	116	4	CID003086323
Drug	4-nitrophenyl)imidazole	UGT1A10 UGT1A7 UGT1A9	2.06e-05	11	116	3	CID000123155
Drug	AC1O5XMV	UGT1A10 UGT1A7 UGT1A9	2.06e-05	11	116	3	CID006442661
Drug	Estrone	UGT1A10 UGT1A7 CYP17A1 UGT1A9 AFP NCOA1	2.37e-05	112	116	6	ctd:D004970
Drug	N-OH-DABZ	UGT1A10 UGT1A7 UGT1A9	2.74e-05	12	116	3	CID000051366
Drug	1-O-beta-D-glucopyranosyl-D-mannitol	UGT1A10 UGT1A7 UGT1A9	2.74e-05	12	116	3	CID000088735
Drug	4-hydroxyestrone	UGT1A10 UGT1A7 UGT1A9	2.74e-05	12	116	3	ctd:C026418
Drug	2,4,6-TCB	UGT1A10 UGT1A7 UGT1A9	2.74e-05	12	116	3	CID000037247
Drug	nonanoyl-N-methylglucamide	UGT1A10 UGT1A7 UGT1A9	2.74e-05	12	116	3	CID000160090
Drug	7,7,7-triphenylheptanoic acid	UGT1A10 UGT1A7 UGT1A9	2.74e-05	12	116	3	CID000276709
Drug	anisole	UGT1A10 SYNE1 UGT1A7 UGT1A9	3.32e-05	36	116	4	CID000007519
Drug	2-hydroxyestrone	UGT1A10 UGT1A7 UGT1A9	3.55e-05	13	116	3	ctd:C024980
Drug	tritanol	UGT1A10 UGT1A7 UGT1A9	3.55e-05	13	116	3	CID000006457
Drug	5-azido-UDP-glucuronic acid	UGT1A10 UGT1A7 UGT1A9	3.55e-05	13	116	3	CID003081279
Drug	cotinine-N-glucuronide	UGT1A10 UGT1A7 UGT1A9	3.55e-05	13	116	3	CID000000411
Drug	alizarin	UGT1A10 UGT1A7 UGT1A9	3.55e-05	13	116	3	ctd:C010078
Drug	isoliquiritigenin	UGT1A10 UGT1A7 CYP17A1 UGT1A9 AFP	3.59e-05	73	116	5	ctd:C040920
Drug	propranolol glucuronide	UGT1A10 UGT1A7 UGT1A9	4.50e-05	14	116	3	CID000119515
Drug	PCB-61	UGT1A10 UGT1A7 UGT1A9	4.50e-05	14	116	3	CID000036401
Drug	AC1L1FK5	UGT1A10 UGT1A7 CYP17A1 UGT1A9 FDFT1 AFP	5.25e-05	129	116	6	CID000003272
Drug	2,2',3,5,5'-pentachlorobiphenyl	UGT1A10 UGT1A7 UGT1A9	5.61e-05	15	116	3	CID000040469
Drug	afloqualone	UGT1A10 UGT1A7 UGT1A9	5.61e-05	15	116	3	CID000002040
Drug	naphthyl sulphate	UGT1A10 UGT1A7 UGT1A9	5.61e-05	15	116	3	CID000114775
Drug	coumarin-3-carboxylic acid	UGT1A10 UGT1A7 UGT1A9	5.61e-05	15	116	3	CID000010752
Drug	bergamottin	UGT1A10 UGT1A7 UGT1A9	5.61e-05	15	116	3	ctd:C068337
Drug	sulforaphane nitrile	UGT1A10 UGT1A7 UGT1A9	5.61e-05	15	116	3	CID000543743
Drug	LY 294002; Up 200; 10uM; PC3; HT_HG-U133A	VPS50 TEX15 HUWE1 LRCH1 ZFHX2 EPS8L3 SPSB3	5.65e-05	191	116	7	4451_UP
Drug	L 654969	UGT1A10 UGT1A7 UGT1A9 FDFT1	6.17e-05	42	116	4	CID000005218
Drug	(-)-Quinpirole hydrochloride [85760-74-3]; Down 200; 15.6uM; MCF7; HT_HG-U133A	NPTX1 EMC1 RABGAP1 ARID1A LRCH1 ATM VPS13B	6.23e-05	194	116	7	3539_DN
Drug	Gabapentin [60142-96-3]; Up 200; 23.4uM; MCF7; HT_HG-U133A	INTS7 RABGAP1 LRCH1 NID1 ATM PCBP4 VPS13B	6.44e-05	195	116	7	3472_UP
Drug	androsterone glucuronide	UGT1A10 UGT1A7 CYP17A1 UGT1A9	6.77e-05	43	116	4	CID000114833
Drug	quercetin-3,4'-diglucoside	UGT1A10 UGT1A7 UGT1A9	6.88e-05	16	116	3	CID005320835
Drug	1'-hydroxyestragole	UGT1A10 UGT1A7 UGT1A9	6.88e-05	16	116	3	CID000040003
Drug	bilirubin-phosphate	UGT1A10 UGT1A7 UGT1A9	6.88e-05	16	116	3	CID005497144
Drug	5 alpha-androstane	UGT1A10 UGT1A7 CYP17A1 UGT1A9 NCOA1	7.05e-05	84	116	5	CID000094144
Drug	Melatonin [73-31-4]; Up 200; 17.2uM; MCF7; HT_HG-U133A	KRT32 CYP17A1 VPS50 CD83 BMP3 VPS13B SENP7	7.09e-05	198	116	7	5393_UP
Drug	diosmetin	UGT1A10 UGT1A7 CYP17A1 UGT1A9 FDFT1	7.46e-05	85	116	5	CID005281612
Drug	3 beta,5 alpha,25R)- 3-hydroxyspirostan-12-one	UGT1A10 UGT1A7 UGT1A9	8.32e-05	17	116	3	CID000003573
Drug	6-hydroxychrysene	UGT1A10 UGT1A7 UGT1A9	8.32e-05	17	116	3	CID000037766
Drug	SureCN12722713	UGT1A10 UGT1A7 UGT1A9	9.94e-05	18	116	3	CID005488034
Drug	ethyl-beta-D-6-glucosiduronic acid	UGT1A10 UGT1A7 UGT1A9	9.94e-05	18	116	3	CID000152226
Drug	Br 2	UGT1A10 UGT1A7 UGT1A9	9.94e-05	18	116	3	CID003060900
Drug	2,3,7-trichlorodibenzo-p-dioxin	UGT1A10 UGT1A7 UGT1A9	9.94e-05	18	116	3	CID000036614
Drug	ApApG	UGT1A10 UGT1A7 UGT1A9	9.94e-05	18	116	3	CID003081975
Drug	C1 11-32	UGT1A10 UGT1A7 UGT1A9	9.94e-05	18	116	3	CID000443077
Drug	C11131	UGT1A10 UGT1A7 UGT1A9	9.94e-05	18	116	3	CID000443076
Drug	isoamyl alcohol	UGT1A10 UGT1A7 UGT1A9 G6PC2	1.05e-04	48	116	4	CID000031260
Drug	EM-652	UGT1A10 UGT1A7 UGT1A9 NCOA1	1.14e-04	49	116	4	CID000155435
Drug	9-OH-risperidone	UGT1A10 UGT1A7 UGT1A9	1.18e-04	19	116	3	CID000475100
Drug	5alpha-spirostan-3beta-ol	UGT1A10 UGT1A7 UGT1A9	1.18e-04	19	116	3	CID000091433
Drug	almokalant	UGT1A10 UGT1A7 UGT1A9	1.18e-04	19	116	3	CID003033962
Drug	mesitylene	SLC25A20 SYNE1 FDFT1	1.38e-04	20	116	3	CID000007947
Drug	tectochrysin	UGT1A10 UGT1A7 UGT1A9	1.38e-04	20	116	3	CID005281954
Drug	AC1L1OBF	UGT1A10 UGT1A7 UGT1A9	1.38e-04	20	116	3	CID000032736
Drug	4'-hydroxydiclofenac	UGT1A10 UGT1A7 UGT1A9	1.38e-04	20	116	3	CID000116545
Drug	entacapone	UGT1A10 UGT1A7 UGT1A9	1.38e-04	20	116	3	ctd:C071192
Drug	mepyramine	UGT1A10 UGT1A7 CYP17A1 UGT1A9 ART4 ATM	1.40e-04	154	116	6	CID000004992
Drug	levo-dromoran tartrate	UGT1A10 UGT1A7 UGT1A9 GRM2 ART4	1.47e-04	98	116	5	CID000003918
Drug	sitafloxacin	UGT1A7 UGT1A9	1.53e-04	4	116	2	ctd:C076246
Drug	hydratropic acid	UGT1A10 UGT1A7	1.53e-04	4	116	2	ctd:C013025
Drug	prostaglandin B1	UGT1A10 UGT1A9	1.53e-04	4	116	2	ctd:C034467
Drug	2-vanillin	UGT1A10 UGT1A7	1.53e-04	4	116	2	ctd:C060843
Drug	diphenylacetic acid	UGT1A10 UGT1A7	1.53e-04	4	116	2	ctd:C037760
Drug	DEPC	UGT1A10 UGT1A7 UGT1A9 CKAP2	1.54e-04	53	116	4	CID000015357
Drug	estriol-16-glucuronide	UGT1A10 UGT1A7 UGT1A9	1.60e-04	21	116	3	CID000122281
Drug	dulcin	UGT1A10 UGT1A7 UGT1A9	1.60e-04	21	116	3	CID000009013
Drug	Benzamidoxime hydrochloride	UGT1A10 UGT1A7 UGT1A9	1.60e-04	21	116	3	CID000069186
Drug	AC1Q6OQF	UGT1A10 UGT1A7 CYP17A1 UGT1A9	1.79e-04	55	116	4	CID000009685
Drug	amonafide	UGT1A10 UGT1A7 UGT1A9	1.85e-04	22	116	3	CID000050515
Drug	plumbagin	UGT1A10 UGT1A7 UGT1A9	1.85e-04	22	116	3	ctd:C014758
Drug	amidoxime	UGT1A10 UGT1A7 UGT1A9	2.12e-04	23	116	3	CID000465967
Drug	estradiol-3-glucuronide	UGT1A10 UGT1A7 UGT1A9	2.12e-04	23	116	3	CID000066651
Drug	phenanthridine	UGT1A10 UGT1A7 UGT1A9	2.12e-04	23	116	3	CID000009189
Drug	cinnamic acid	UGT1A10 UGT1A7 CYP17A1	2.41e-04	24	116	3	ctd:C029010
Drug	AS-3201	UGT1A10 UGT1A7 UGT1A9	2.41e-04	24	116	3	CID000153948
Drug	aminopyrine	UGT1A10 UGT1A7 CYP17A1 APC2 UGT1A9 G6PC2	2.47e-04	171	116	6	CID000006009
Drug	fisetin	UGT1A10 UGT1A7 UGT1A9 AFP	2.50e-04	60	116	4	ctd:C017875
Drug	irinotecan	WAPL UGT1A10 UGT1A7 UGT1A9 SLC25A36 TLR4 NCOA1 NID1 EIF2AK4 ATM VPS13B XPO7	2.51e-04	703	116	12	ctd:C051890
Drug	ethyl 2-(4-chlorophenyl)-5-(2-furyl)-4-oxzoleacetate	UGT1A7 UGT1A9	2.55e-04	5	116	2	ctd:C052488
Drug	isovaleric acid	UGT1A10 UGT1A7	2.55e-04	5	116	2	ctd:C008216
Drug	biphenylylacetic acid	UGT1A10 UGT1A7	2.55e-04	5	116	2	ctd:C012776
Disease	N-acetyl-4-chlorophenylalanine measurement	UGT1A10 UGT1A7 UGT1A9	4.74e-07	5	108	3	EFO_0801060
Disease	5-hydroxyindole sulfate measurement	UGT1A10 UGT1A7 UGT1A9	4.74e-07	5	108	3	EFO_0800085
Disease	nuclear receptor subfamily 1 group D member 2 measurement	UGT1A10 UGT1A7 UGT1A9	4.74e-07	5	108	3	EFO_0801853
Disease	X-21339 measurement	UGT1A10 UGT1A7 UGT1A9	1.65e-06	7	108	3	EFO_0800808
Disease	X-11793--oxidized bilirubin measurement	UGT1A10 UGT1A7 UGT1A9	2.63e-06	8	108	3	EFO_0021260
Disease	Succinimide measurement	UGT1A10 UGT1A7 UGT1A9	2.63e-06	8	108	3	EFO_0022118
Disease	X-11530 measurement	UGT1A10 UGT1A7 UGT1A9	2.63e-06	8	108	3	EFO_0021249
Disease	sulfate of piperine metabolite C16H19NO3 (2) measurement	UGT1A10 UGT1A7 UGT1A9	2.63e-06	8	108	3	EFO_0801034
Disease	cholelithiasis, bilirubin measurement	UGT1A10 UGT1A7 UGT1A9	2.63e-06	8	108	3	EFO_0004570, EFO_0004799
Disease	X-11522 measurement	UGT1A10 UGT1A7 UGT1A9	2.63e-06	8	108	3	EFO_0800696
Disease	X-10458 measurement	UGT1A10 UGT1A7 UGT1A9	2.63e-06	8	108	3	EFO_0800692
Disease	X-24849 measurement	UGT1A10 UGT1A7 UGT1A9	2.63e-06	8	108	3	EFO_0800909
Disease	serum N-desmethylclozapine measurement	UGT1A10 UGT1A7 UGT1A9	2.63e-06	8	108	3	EFO_0600043
Disease	plasma clozapine measurement	UGT1A10 UGT1A7 UGT1A9	2.63e-06	8	108	3	EFO_0600038
Disease	membrane-associated progesterone receptor component 1 measurement	UGT1A10 UGT1A7 UGT1A9	2.63e-06	8	108	3	EFO_0802740
Disease	X-16946 measurement	UGT1A10 UGT1A7 UGT1A9	2.63e-06	8	108	3	EFO_0800766
Disease	X-11442 measurement	UGT1A10 UGT1A7 UGT1A9	3.94e-06	9	108	3	EFO_0021236
Disease	X-11441 measurement	UGT1A10 UGT1A7 UGT1A9	3.94e-06	9	108	3	EFO_0021235
Disease	circulating cell free DNA measurement	UGT1A10 UGT1A7 UGT1A9	3.94e-06	9	108	3	EFO_0004739
Disease	sulfate of piperine metabolite C18H21NO3 (3) measurement	UGT1A10 UGT1A7 UGT1A9	3.94e-06	9	108	3	EFO_0801037
Disease	sulfate of piperine metabolite C18H21NO3 (1) measurement	UGT1A10 UGT1A7 UGT1A9	3.94e-06	9	108	3	EFO_0801036
Disease	X-11880 measurement	UGT1A10 UGT1A7 UGT1A9	3.94e-06	9	108	3	EFO_0800698
Disease	protein-tyrosine kinase 6 measurement	UGT1A10 UGT1A7 UGT1A9	3.94e-06	9	108	3	EFO_0020691
Disease	testis-specific chromodomain protein Y 1 measurement	UGT1A10 UGT1A7 UGT1A9	3.94e-06	9	108	3	EFO_0802127
Disease	bilirubin measurement, response to xenobiotic stimulus	UGT1A10 UGT1A7 UGT1A9	3.94e-06	9	108	3	EFO_0004570, GO_0009410
Disease	bilirubin measurement, response to tenofovir	UGT1A10 UGT1A7 UGT1A9	5.62e-06	10	108	3	EFO_0004570, EFO_0009279
Disease	X-21448 measurement	UGT1A10 UGT1A7 UGT1A9	5.62e-06	10	108	3	EFO_0800816
Disease	UDP-glucuronosyltransferase 1-6 measurement	UGT1A10 UGT1A7 UGT1A9	5.62e-06	10	108	3	EFO_0802185
Disease	X-23974 measurement	UGT1A10 UGT1A7 UGT1A9	5.62e-06	10	108	3	EFO_0800867
Disease	pregnenetriol sulfate measurement	UGT1A10 UGT1A7 UGT1A9	7.70e-06	11	108	3	EFO_0800586
Disease	plasma N-desmethylclozapine measurement	UGT1A10 UGT1A7 UGT1A9	7.70e-06	11	108	3	EFO_0600039
Disease	histidine betaine (hercynine) measurement	UGT1A10 UGT1A7 UGT1A9	7.70e-06	11	108	3	EFO_0800972
Disease	X-21796 measurement	UGT1A10 UGT1A7 UGT1A9	7.70e-06	11	108	3	EFO_0800825
Disease	insomnia, bilirubin measurement	UGT1A10 UGT1A7 UGT1A9	7.70e-06	11	108	3	EFO_0004570, EFO_0004698
Disease	aldosterone measurement	UGT1A10 UGT1A7 UGT1A9	7.70e-06	11	108	3	EFO_0010219
Disease	vitamin D deficiency	UGT1A10 UGT1A7 UGT1A9 GC	1.02e-05	37	108	4	EFO_0003762
Disease	p-cresol glucuronide measurement	UGT1A10 UGT1A7 UGT1A9	1.02e-05	12	108	3	EFO_0800079
Disease	biliverdin measurement	UGT1A10 UGT1A7 UGT1A9	1.02e-05	12	108	3	EFO_0021033
Disease	pregnenetriol disulfate measurement	UGT1A10 UGT1A7 UGT1A9	1.33e-05	13	108	3	EFO_0800587
Disease	retinol dehydrogenase 16 measurement	UGT1A10 UGT1A7 UGT1A9	1.33e-05	13	108	3	EFO_0802007
Disease	low density lipoprotein cholesterol measurement, body fat percentage	UGT1A10 UGT1A7 UGT1A9	3.12e-05	17	108	3	EFO_0004611, EFO_0007800
Disease	X-21441 measurement	UGT1A10 UGT1A7 UGT1A9	3.12e-05	17	108	3	EFO_0800814
Disease	vitamin D measurement, COVID-19	UGT1A10 UGT1A7 UGT1A9 GC	3.17e-05	49	108	4	EFO_0004631, MONDO_0100096
Disease	angiopoietin-related protein 1 measurement	UGT1A10 UGT1A7 UGT1A9	3.74e-05	18	108	3	EFO_0801382
Disease	indole-3-carboxylate measurement	UGT1A10 UGT1A9	3.97e-05	3	108	2	EFO_0800043
Disease	blood 4-oxo-retinoic acid measurement	UGT1A10 UGT1A9	3.97e-05	3	108	2	EFO_0022216
Disease	tissue factor measurement	UGT1A10 UGT1A7 UGT1A9	6.04e-05	21	108	3	EFO_0010623
Disease	Liver carcinoma	CYP17A1 ARID1A NCAPH KMT2C FDFT1 AFP TLR4 EPS8L3 ATM	1.06e-04	507	108	9	C2239176
Disease	carotid stenosis (implicated_via_orthology)	TLR4 MFN2	1.32e-04	5	108	2	DOID:13001 (implicated_via_orthology)
Disease	Klatskin's tumor (is_implicated_in)	ARID1A KMT2C	1.32e-04	5	108	2	DOID:4927 (is_implicated_in)
Disease	neuroblastoma, cutaneous melanoma	UGT1A10 UGT1A7 UGT1A9	1.46e-04	28	108	3	EFO_0000389, EFO_0000621
Disease	xanthurenate measurement	UGT1A10 UGT1A7 UGT1A9	1.63e-04	29	108	3	EFO_0010551
Disease	lung non-small cell carcinoma (is_implicated_in)	RARB E2F3 ARID1A KMT2C ATM	1.63e-04	139	108	5	DOID:3908 (is_implicated_in)
Disease	response to dolutegravir	UGT1A10 UGT1A7 UGT1A9	1.80e-04	30	108	3	EFO_0600017
Disease	3-carboxy-4-methyl-5-pentyl-2-furanpropionate (3-CMPFP) measurement	UGT1A10 UGT1A9	1.97e-04	6	108	2	EFO_0800566
Disease	metabolite measurement	UGT1A10 UGT1A7 UGT1A9 ICE1 SORCS1 DHRS4-AS1 SLC47A1 G6PC2 PCBP4	2.22e-04	560	108	9	EFO_0004725
Disease	cholelithiasis	UGT1A10 UGT1A7 UGT1A9 VPS13B	3.12e-04	88	108	4	EFO_0004799
Disease	Prostatic Neoplasms	CYP17A1 ARID1A IVNS1ABP KMT2C TLR4 NCOA1 SERINC3 EPS8L3 ATM	4.44e-04	616	108	9	C0033578
Disease	Malignant neoplasm of prostate	CYP17A1 ARID1A IVNS1ABP KMT2C TLR4 NCOA1 SERINC3 EPS8L3 ATM	4.44e-04	616	108	9	C0376358
Disease	urate measurement, bone density	UGT1A10 SYNE1 UGT1A7 UGT1A9 E2F3 RANBP17 A2ML1 EIF2AK4 USH2A	4.60e-04	619	108	9	EFO_0003923, EFO_0004531
Disease	arthritis (is_implicated_in)	GC TLR4	4.70e-04	9	108	2	DOID:848 (is_implicated_in)
Disease	nasopharynx carcinoma (is_marker_for)	ARID1A KMT2C ATM	5.29e-04	43	108	3	DOID:9261 (is_marker_for)
Disease	Malignant neoplasm of breast	RARB SYNE1 CYP17A1 APC2 UGT1A9 ARID1A SORCS1 UNC45B AFP NCOA1 ATM VPS13B	5.72e-04	1074	108	12	C0006142
Disease	Abnormality of nervous system morphology	APC2 FDFT1	5.86e-04	10	108	2	C4022810
Disease	indoleacetate measurement	UGT1A10 UGT1A9	5.86e-04	10	108	2	EFO_0021015
Disease	cleft lip	RARB SYNE1 ICE1 DMRT2 GVINP1 NID1	6.35e-04	284	108	6	EFO_0003959
Disease	Breast Carcinoma	RARB SYNE1 CYP17A1 APC2 ARID1A AFP NCOA1 ATM	8.29e-04	538	108	8	C0678222
Disease	X-24588 measurement	UGT1A10 UGT1A9	1.01e-03	13	108	2	EFO_0800898
Disease	inositol measurement	MYO10 SYT4	1.17e-03	14	108	2	EFO_0010504
Disease	Adenocarcinoma Of Esophagus	ARID1A TLR4	1.17e-03	14	108	2	C0279628
Disease	urate measurement, spine bone mineral density	UGT1A10 UGT1A7 UGT1A9	1.27e-03	58	108	3	EFO_0004531, EFO_0007701
Disease	N,N,N-trimethyl-5-aminovalerate measurement	CD83 SLC47A1	1.35e-03	15	108	2	EFO_0800090
Disease	congenital heart disease (implicated_via_orthology)	USP17L2 KMT2C USP17L8	2.10e-03	69	108	3	DOID:1682 (implicated_via_orthology)
Disease	breast cancer (is_implicated_in)	CYP17A1 ARID1A TLR4 ATM	2.28e-03	150	108	4	DOID:1612 (is_implicated_in)
Disease	prostate cancer (is_marker_for)	E2F3 KMT2C AFP NCOA1	2.63e-03	156	108	4	DOID:10283 (is_marker_for)
Disease	Granulomatous Slack Skin	ARID1A ATM	2.92e-03	22	108	2	C0376407
Disease	Nasopharyngeal carcinoma	SYNE1 ARID1A	2.92e-03	22	108	2	C2931822
Disease	Lymphoma, T-Cell, Cutaneous	ARID1A ATM	3.19e-03	23	108	2	C0079773
Disease	Mammary Carcinoma, Human	RARB SYNE1 CYP17A1 APC2 AFP NCOA1 ATM	3.23e-03	525	108	7	C4704874
Disease	Mammary Neoplasms, Human	RARB SYNE1 CYP17A1 APC2 AFP NCOA1 ATM	3.23e-03	525	108	7	C1257931
Disease	Mammary Neoplasms	RARB SYNE1 CYP17A1 APC2 AFP NCOA1 ATM	3.30e-03	527	108	7	C1458155
Disease	Intrahepatic Cholangiocarcinoma	ARID1A KMT2C	3.48e-03	24	108	2	C0345905
Disease	Extrahepatic Cholangiocarcinoma	ARID1A KMT2C	3.48e-03	24	108	2	C3805278
Disease	thyroxine measurement	UGT1A10 UGT1A7 UGT1A9	3.54e-03	83	108	3	EFO_0005130
Disease	creatinine measurement	USP45 RARB DCDC1 E2F3 RASL12 ARID1A LIPH FDFT1 SLC47A1 CTSS	3.58e-03	995	108	10	EFO_0004518

Protein segments in the cluster

Peptide	Gene	Start	Entry
LALKTAYQSNTVAAC	NAIP	866	Q13075
STLLNCSYTQNCTKT	ADGRL4	11	Q9HBW9
QTEALYILTKCNSTR	BBS5	91	Q8N3I7
LTKSENILSATLYFC	BMP3	121	P12645
ATKIISKSAAQNYTC	ANKRD30B	441	Q9BXX2
NLSLSSNSLCRLYKF	EIF2AK4	1246	Q9P2K8
TSAKNVSCYIQNLLL	BTN1A1	211	Q13410
TAFSVCYSALLTKTN	GRM2	641	Q14416
KSTYEVSLALSCFLN	GVINP1	666	Q7Z2Y8
LRCLKNSATSTTNLY	A2ML1	1121	A8K2U0
VTTSKQLYTVAVSCL	CCNJL	76	Q8IV13
KTIKSISYQISTNCS	ABITRAM	61	Q9NX38
NNSFLQTLKYCSVSE	ADAMTS20	191	P59510
YNSSTISLTSKNCRN	ADAMTS20	1571	P59510
NTETRTSCLIKYNVS	CKAP2	581	Q8WWK9
LASCTFNTLSTINLK	RASL12	216	Q9NYN1
TSYAQLLAATCLSKL	RANBP17	56	Q9H2T7
SLCQLGKYTTNSSAD	RARB	201	P10826
YLKASTTLTCVNLFV	INTS6L	371	Q5JSJ4
ENYSSALSCIAESLK	INTS7	581	Q9NVH2
YTSKLSFSSCAELNL	KCTD19	71	Q17RG1
VYNLATCSTKALSGN	NPTX1	391	Q15818
SSAASSLKKQYIQCL	ARID1A	1086	O14497
SLKIRNTTSCNSGTY	CD83	91	Q01151
SSIIGDYKQICSQLS	RABGAP1	931	Q9Y3P9
AQYLITACLETAKST	PCBP4	301	P57723
LISILKLSCSSTYIN	OR8G5	216	Q8NG78
SYKSNSKNNSCSISA	DCDC1	116	M0R2J8
VNIQTKSQSISYESC	OR1S1	96	Q8NH92
NCFILYSSTAQAKNS	KMT2C	4241	Q8NEZ4
SKLFYCSNGNLSSIT	KCTD21	161	Q4G0X4
KTSVQCIAFQYSTVL	NEDD1	291	Q8NHV4
CIAFQYSTVLTKSSL	NEDD1	296	Q8NHV4
IVASEKTSNNTYLCL	IVNS1ABP	291	Q9Y6Y0
LTYLSINCTSISLNM	NLRP11	691	P59045
CLSKTYLSSSCQAAS	KRT32	61	Q14532
SLYSFALKCLISLST	KCNN1	136	Q92952
LSSSLKTCYKYLNQT	FDFT1	36	P37268
LVIASCQYSLLKSVQ	PCNX3	826	Q9H6A9
KQTRLYGITTALSQC	NID1	1191	P14543
VALNTCSYNSILSIT	EPS8L3	101	Q8TE67
SSYECTIENSLLKQT	HHLA2	206	Q9UM44
GKCTSLLQLYDASNS	MYO10	701	Q9HD67
YLSIQACQIKTADSL	LRCH1	286	Q9Y2L9
CLLQIQASSGESKYT	SLC25A20	136	O43772
LNLTDSENATCLYAK	LAMP2	31	P13473
SISNCSQTLSYDLTA	IL10RA	71	Q13651
YTRKNLTCAQTINSS	LIPH	46	Q8WWY8
LSVLSKLSQLYCSLV	HUWE1	931	Q7Z6Z7
EKLQLVISYTGSNCS	MFN2	671	O95140
KYGSCSTILLDNSTA	CCNYL3	16	P0C7X3
SLCVSLNAIYTTKVL	SLC35C1	206	Q96A29
ASCAANNPSLKLTYT	ATM	2321	Q13315
LVSTLTYKCQSNSLA	APC2	581	O95996
DDYSLKNTSQLTQCS	ICE1	1241	Q9Y2F5
AYIQILTTNTSTTSC	E2F3	56	O00716
SDTLLYQQCLLNATT	DMRT2	351	Q9Y5R5
TQTNTAALLNVCTSY	LINC01599	306	Q8WXQ3
TTNRLCVSNKAVYSL	DHRS4-AS1	26	Q9P1J3
TNVISLICFNTSYKN	CYP17A1	176	P05093
LSNTLDLNSKLAYCE	CCDC183	431	Q5T5S1
CYNLSGNLASLTTSK	ATRNL1	776	Q5VV63
NNYTLSFRLLCALTS	G6PC2	286	Q9NQR9
NIDLSLTCNYISSVS	CDC20B	266	Q86Y33
LCQLSSYAKTELGSQ	KANSL2	116	Q9H9L4
INCKSSQSVLYSSNN	IGKV4-1	41	P06312
SLSAQNLVDCSTEKY	CTSS	161	P25774
SSKDSLACFNQTYTI	EMC1	361	Q8N766
TIETSLAQYSLTQLC	FLAD1	386	Q8NFF5
YLTRIQVTLLCNSSA	BLID	91	Q8IZY5
LLKLNQLYNCSSSLS	MEP1B	246	Q16820
CYNLSATNDSTILDK	CD37	181	P11049
SYICSQQDTLSNKIT	AFP	286	P02771
ASSRCQLTLSYSKTV	nan	101	A6NNC1
IGLYLCSSANSSTLK	OR1E1	256	P30953
LQLCTSAYKQDTLFS	GARIN2	151	Q8N9W8
ATKSLLVCNSRILSY	RTKN	71	Q9BST9
LLISLCYQSTTNTLT	SYT4	291	Q9H2B2
CYQSTTNTLTVVVLK	SYT4	296	Q9H2B2
TIYACVKSNGTQITT	USH2A	3091	O75445
LQKQSSGCYSLSITS	SENP7	716	Q9BQF6
LSTVLYILNSCSLSV	TCAIM	121	Q8N3R3
ISSTQENLNSLCRKY	SYNE1	2356	Q8NF91
LYCNQLSSTDLLKTE	NCOA1	1366	Q15788
TLQLYCSSALENTVS	SMG1	1351	Q96Q15
LAAATSKTCATTIAY	SLC25A36	231	Q96CQ1
SLINSSSTLLCQYIN	IARS1	1161	P41252
KVTRSCASATSLQYL	SPSB3	266	Q6PJ21
TLCYKQTLSLTVLTC	MRGPRX1	21	Q96LB2
CDTLISQTYGSQNLK	SLC47A1	96	Q96FL8
QRTASLLNSCKAILY	TET1	921	Q8NFU7
YSTCIKLSTENKITT	NCAPH	111	Q15003
YSCISELNSKLQDTL	VPS50	216	Q96JG6
ILYSVATTLVNCTNS	UNC45B	571	Q8IWX7
NSTLTNQKLYLLCSR	RNASE13	126	Q5GAN3
AQSKCLINVSFSLYS	LINC02912	61	Q8N9X5
AKIAVLSSSCTIQAY	TRAM1L1	296	Q8N609
KSTRIIYCDSNSQIS	ZNF804B	821	A4D1E1
TLSQSYITTSKECSI	USP45	606	Q70EL2
LERSLNCTVKTYSTS	UGT1A10	66	Q9HAW8
AILSSSQFYGKLQTC	ZSCAN32	266	Q9NX65
DVCNYSTTTKGNLSI	ZFHX2	511	Q9C0A1
LLTTLSNRVCSQYAA	GC	211	P02774
SKNLAQVKCSSYSES	WAPL	86	Q7Z5K2
LGRSLNCTVKTYSTS	UGT1A9	66	O60656
LCLLYSSIRTSTNSQ	SERINC3	346	Q13530
INCLSAYRVKTVTSS	ZMYM6	301	O95789
LLYTQALAALSVKCS	UBR3	1566	Q6ZT12
AVSQLSCSSSYLVLA	WDR93	416	Q6P2C0
GSIQNVELKYCSTSL	VPS13B	851	Q7Z7G8
KCQLLLERGSSSYSQ	XPO7	46	Q9UIA9
SSYSQLLAATCLTKL	XPO7	56	Q9UIA9
ACSITSVLSQQAYVL	USP17L8	356	P0C7I0
KTCDKVYSLIQSLTS	PPIP5K2	661	O43314
SQSSDLKTIYQTGCQ	TEX15	201	Q9BXT5
LKTIYQTGCQTSTVF	TEX15	206	Q9BXT5
SSLSKDCSLGQSYLN	SORCS1	751	Q8WY21
DLSSNKIQSIYCTDL	TLR4	181	O00206
LATLANSESSYNCLL	VIRMA	1331	Q69YN4
TSYLQSQLKSLCAST	WWC3	346	Q9ULE0
LGRSLNCTVKTYSTS	UGT1A7	66	Q9HAW7
ACSITSVLSQQAYVL	USP17L2	356	Q6R6M4
YKFSETALSILNSCQ	nan	71	Q9UFV3
QSLQYFSITCNKVES	LRRC8C	706	Q8TDW0
STGNLSTYNCQLLKA	ART4	271	Q93070