Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	regulation of rDNA heterochromatin formation	PHF2 MACROH2A1	6.99e-06	3	32	2	GO:0061187
GeneOntologyBiologicalProcess	ERBB2-EGFR signaling pathway	HBEGF AREG	6.49e-05	8	32	2	GO:0038134
GeneOntologyBiologicalProcess	detection of visible light	GRK7 NMT2 TULP1	9.38e-05	57	32	3	GO:0009584
GeneOntologyBiologicalProcess	rDNA heterochromatin formation	PHF2 MACROH2A1	1.04e-04	10	32	2	GO:0000183
GeneOntologyBiologicalProcess	regulation of opsin-mediated signaling pathway	GRK7 NMT2	1.04e-04	10	32	2	GO:0022400
GeneOntologyBiologicalProcess	nucleolar chromatin organization	PHF2 MACROH2A1	1.27e-04	11	32	2	GO:1990700
GeneOntologyBiologicalProcess	G protein-coupled opsin signaling pathway	GRK7 NMT2	1.80e-04	13	32	2	GO:0016056
GeneOntologyBiologicalProcess	detection of light stimulus	GRK7 NMT2 TULP1	2.30e-04	77	32	3	GO:0009583
GeneOntologyBiologicalProcess	DNA-templated transcription initiation	PHF2 GTF2F1 MACROH2A1 GTF3C1	4.31e-04	231	32	4	GO:0006352
GeneOntologyBiologicalProcess	phototransduction, visible light	GRK7 NMT2	4.35e-04	20	32	2	GO:0007603
GeneOntologyBiologicalProcess	nucleolus organization	PHF2 MACROH2A1	4.81e-04	21	32	2	GO:0007000
GeneOntologyBiologicalProcess	regulation of heterochromatin formation	PHF2 MACROH2A1	6.30e-04	24	32	2	GO:0031445
GeneOntologyBiologicalProcess	ERBB2 signaling pathway	HBEGF AREG	7.99e-04	27	32	2	GO:0038128
GeneOntologyBiologicalProcess	rRNA metabolic process	NVL MACROH2A1 GTF3C1 NGDN	8.29e-04	275	32	4	GO:0016072
GeneOntologyBiologicalProcess	N-terminal protein amino acid modification	METAP2 NMT2	9.22e-04	29	32	2	GO:0031365
GeneOntologyBiologicalProcess	cellular response to light stimulus	TRPM1 GRK7 NMT2	1.06e-03	130	32	3	GO:0071482
Domain	EGF_rcpt_ligand	HBEGF AREG	4.25e-05	6	32	2	IPR015497
Domain	AAA	NVL IQCA1	1.54e-03	34	32	2	PS00674
Domain	AAA	NVL IQCA1	3.57e-03	52	32	2	PF00004
Domain	ATPase_AAA_core	NVL IQCA1	3.85e-03	54	32	2	IPR003959
Domain	Zinc_finger_PHD-type_CS	PHF2 CHD5	5.53e-03	65	32	2	IPR019786
Domain	PHD	PHF2 CHD5	7.30e-03	75	32	2	PF00628
Domain	Znf_PHD-finger	PHF2 CHD5	8.07e-03	79	32	2	IPR019787
Domain	IQ	IQCD IQCA1	8.47e-03	81	32	2	SM00015
Domain	PHD	PHF2 CHD5	1.01e-02	89	32	2	SM00249
Domain	IQ_motif_EF-hand-BS	IQCD IQCA1	1.04e-02	90	32	2	IPR000048
Domain	Znf_PHD	PHF2 CHD5	1.06e-02	91	32	2	IPR001965
Domain	IQ	IQCD IQCA1	1.10e-02	93	32	2	PS50096
Domain	ZF_PHD_2	PHF2 CHD5	1.15e-02	95	32	2	PS50016
Domain	ZF_PHD_1	PHF2 CHD5	1.17e-02	96	32	2	PS01359
Pathway	REACTOME_THE_PHOTOTRANSDUCTION_CASCADE	METAP2 GRK7 NMT2	1.66e-05	34	21	3	M27183
Pathway	REACTOME_EGFR_INTERACTS_WITH_PHOSPHOLIPASE_C_GAMMA	HBEGF AREG	7.56e-05	9	21	2	MM14853
Pathway	REACTOME_EGFR_INTERACTS_WITH_PHOSPHOLIPASE_C_GAMMA	HBEGF AREG	7.56e-05	9	21	2	M27133
Pathway	REACTOME_SHC1_EVENTS_IN_EGFR_SIGNALING	HBEGF AREG	1.63e-04	13	21	2	MM14701
Pathway	REACTOME_SHC1_EVENTS_IN_EGFR_SIGNALING	HBEGF AREG	1.90e-04	14	21	2	M719
Pathway	PID_ERBB_NETWORK_PATHWAY	HBEGF AREG	2.19e-04	15	21	2	M201
Pathway	REACTOME_ESR_MEDIATED_SIGNALING	GTF2F1 STAG2 HBEGF AREG	2.80e-04	220	21	4	M27794
Pathway	REACTOME_GAB1_SIGNALOSOME	HBEGF AREG	2.84e-04	17	21	2	MM14700
Pathway	REACTOME_GAB1_SIGNALOSOME	HBEGF AREG	2.84e-04	17	21	2	M10450
Pathway	REACTOME_VISUAL_PHOTOTRANSDUCTION	METAP2 GRK7 NMT2	4.20e-04	100	21	3	M27158
Pathway	REACTOME_ESTROGEN_DEPENDENT_NUCLEAR_EVENTS_DOWNSTREAM_OF_ESR_MEMBRANE_SIGNALING	HBEGF AREG	5.72e-04	24	21	2	M27952
Pathway	REACTOME_SIGNALING_BY_EGFR_IN_CANCER	HBEGF AREG	6.21e-04	25	21	2	M563
Pathway	REACTOME_SIGNALING_BY_NUCLEAR_RECEPTORS	GTF2F1 STAG2 HBEGF AREG	8.60e-04	296	21	4	M27869
Pathway	REACTOME_EGFR_DOWNREGULATION	HBEGF AREG	9.58e-04	31	21	2	MM14705
Pathway	REACTOME_THE_PHOTOTRANSDUCTION_CASCADE	METAP2 NMT2	9.58e-04	31	21	2	MM14896
Pathway	REACTOME_EGFR_DOWNREGULATION	HBEGF AREG	9.58e-04	31	21	2	M16597
Pathway	REACTOME_ESR_MEDIATED_SIGNALING	GTF2F1 HBEGF AREG	9.64e-04	133	21	3	MM15529
Pathway	WP_ERBB_SIGNALING_PATHWAY	HBEGF AREG	2.10e-03	46	21	2	MM15950
Pathway	REACTOME_SIGNALING_BY_EGFR	HBEGF AREG	2.38e-03	49	21	2	MM14695
Pathway	REACTOME_SIGNALING_BY_NUCLEAR_RECEPTORS	GTF2F1 HBEGF AREG	2.72e-03	191	21	3	MM15586
Pathway	REACTOME_SIGNALING_BY_EGFR	HBEGF AREG	2.78e-03	53	21	2	M27039
Pathway	WP_15Q11Q13_COPY_NUMBER_VARIATION	TRPM1 UBN1	3.44e-03	59	21	2	M48104
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	ZNF512B NVL PHF2 UBN1 GTF3C1 METAP2 STAG2 CHD5	6.05e-08	608	32	8	36089195
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	ZNF512B NVL PHF2 SRP72 HMGN2 MACROH2A1 UBN1 RPS3A STAG2	1.35e-07	954	32	9	36373674
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	CYLC1 SRP72 HMGN2 MACROH2A1 GTF3C1 STAG2 CHD5 BAHCC1 BBOF1 NGDN	4.07e-07	1442	32	10	35575683
Pubmed	Metalloproteinase-mediated, context-dependent function of amphiregulin and HB-EGF in human keratinocytes and skin.	HBEGF AREG	8.20e-07	2	32	2	19609315
Pubmed	Retinoid-induced epidermal hyperplasia is mediated by epidermal growth factor receptor activation via specific induction of its ligands heparin-binding EGF and amphiregulin in human skin in vivo.	HBEGF AREG	8.20e-07	2	32	2	16470170
Pubmed	The role of heparin-binding EGF-like growth factor and amphiregulin in the epidermal proliferation of psoriasis in cooperation with TNFalpha.	HBEGF AREG	2.46e-06	3	32	2	17960400
Pubmed	Involvement of heparin-binding EGF-like growth factor and its processing by metalloproteinases in early epithelial morphogenesis of the submandibular gland.	HBEGF AREG	4.92e-06	4	32	2	11518516
Pubmed	TACE cleavage of proamphiregulin regulates GPCR-induced proliferation and motility of cancer cells.	HBEGF AREG	4.92e-06	4	32	2	12743035
Pubmed	The N-DRC forms a conserved biochemical complex that maintains outer doublet alignment and limits microtubule sliding in motile axonemes.	IQCD IQCA1	4.92e-06	4	32	2	23427265
Pubmed	Amphiregulin is an implantation-specific and progesterone-regulated gene in the mouse uterus.	HBEGF AREG	4.92e-06	4	32	2	8592515
Pubmed	Differential ErbB1 signaling in squamous cell versus basal cell carcinoma of the skin.	HBEGF AREG	8.19e-06	5	32	2	17525275
Pubmed	Mechanisms by which gram-positive bacteria and tobacco smoke stimulate mucin induction through the epidermal growth factor receptor (EGFR).	HBEGF AREG	8.19e-06	5	32	2	12568494
Pubmed	TNRC6 proteins modulate hepatitis C virus replication by spatially regulating the binding of miR-122/Ago2 complexes to viral RNA.	PHF2 SRP72 HMGN2 GTF2F1 RPS3A	1.00e-05	317	32	5	30997501
Pubmed	Heparin-binding epidermal growth factor-like growth factor signaling in flow-induced arterial remodeling.	HBEGF AREG	1.23e-05	6	32	2	18436796
Pubmed	Mechanisms of reduced fertility in Hoxa-10 mutant mice: uterine homeosis and loss of maternal Hoxa-10 expression.	HBEGF AREG	1.23e-05	6	32	2	8787743
Pubmed	Linking nuclear matrix-localized PIAS1 to chromatin SUMOylation via direct binding of histones H3 and H2A.Z.	HMGN2 MACROH2A1 RPS3A BAHCC1	1.37e-05	159	32	4	34537242
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	ZNF512B PHF2 HMGN2 UBN1 GTF3C1 RPS3A STAG2 NGDN	1.70e-05	1294	32	8	30804502
Pubmed	Rhbdf2 mutations increase its protein stability and drive EGFR hyperactivation through enhanced secretion of amphiregulin.	HBEGF AREG	2.29e-05	8	32	2	24825892
Pubmed	HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.	MRPS33 PHF2 SRP72 HMGN2 MACROH2A1 TRPM1 METAP2 NGDN	2.58e-05	1371	32	8	36244648
Pubmed	HB-EGF decelerates cell proliferation synergistically with TGFalpha in perinatal distal lung development.	HBEGF AREG	2.94e-05	9	32	2	18069687
Pubmed	Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.	NVL HMGN2 GTF2F1 MACROH2A1 UBN1 GTF3C1 STAG2	3.12e-05	1014	32	7	32416067
Pubmed	Human transcription factor protein interaction networks.	ZNF512B MRPS33 PHF2 SRP72 UBN1 GTF3C1 RPS3A CHD5	3.47e-05	1429	32	8	35140242
Pubmed	ErbB/HER ligands in human breast cancer, and relationships with their receptors, the bio-pathological features and prognosis.	HBEGF AREG	3.67e-05	10	32	2	17962208
Pubmed	Mouse chromosomal location of three EGF receptor ligands: amphiregulin (Areg), betacellulin (Btc), and heparin-binding EGF (Hegfl).	HBEGF AREG	3.67e-05	10	32	2	7590736
Pubmed	The epidermal growth factor receptor couples transforming growth factor-alpha, heparin-binding epidermal growth factor-like factor, and amphiregulin to Neu, ErbB-3, and ErbB-4.	HBEGF AREG	3.67e-05	10	32	2	8702723
Pubmed	Implantation and decidualization defects in prolactin receptor (PRLR)-deficient mice are mediated by ovarian but not uterine PRLR.	HBEGF AREG	4.49e-05	11	32	2	10803598
Pubmed	KGF and EGF signalling block hair follicle induction and promote interfollicular epidermal fate in developing mouse skin.	HBEGF AREG	4.49e-05	11	32	2	19474150
Pubmed	Characterizing ZC3H18, a Multi-domain Protein at the Interface of RNA Production and Destruction Decisions.	MRPS33 SRP72 HMGN2 MACROH2A1 RPS3A NGDN	4.80e-05	731	32	6	29298432
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	PHF2 SRP72 HMGN2 GTF2F1 GTF3C1 METAP2 STAG2	5.32e-05	1103	32	7	34189442
Pubmed	The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.	NVL SRP72 MACROH2A1 GTF3C1 RPS3A NGDN	5.91e-05	759	32	6	35915203
Pubmed	An EGFR-ERK-SOX9 signaling cascade links urothelial development and regeneration to cancer.	HBEGF AREG	6.36e-05	13	32	2	21512138
Pubmed	Cytosolic phospholipase A2alpha is crucial [correction of A2alpha deficiency is crucial] for 'on-time' embryo implantation that directs subsequent development.	HBEGF AREG	7.41e-05	14	32	2	12050136
Pubmed	The ubiquitin-specific protease USP36 SUMOylates EXOSC10 and promotes the nucleolar RNA exosome function in rRNA processing.	NVL SRP72 MACROH2A1 GTF3C1 NGDN	7.48e-05	483	32	5	36912080
Pubmed	NuRD subunit CHD4 regulates super-enhancer accessibility in rhabdomyosarcoma and represents a general tumor dependency.	ZNF512B MACROH2A1 CHD5	1.18e-04	103	32	3	32744500
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	SRP72 MACROH2A1 GTF3C1 METAP2 RPS3A CHD5 NGDN	1.21e-04	1257	32	7	36526897
Pubmed	An atlas of combinatorial transcriptional regulation in mouse and man.	ZNF512B PHF2 GTF2F1 GTF3C1 AEBP1 ANKEF1	1.31e-04	877	32	6	20211142
Pubmed	Identification of a Pax6-dependent epidermal growth factor family signaling source at the lateral edge of the embryonic cerebral cortex.	HBEGF AREG	1.39e-04	19	32	2	12878679
Pubmed	BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.	PHF2 SRP72 HMGN2 MACROH2A1 METAP2 RPS3A NGDN	1.62e-04	1318	32	7	30463901
Pubmed	Mig-6 is required for appropriate lung development and to ensure normal adult lung homeostasis.	HBEGF AREG	1.70e-04	21	32	2	19710174
Pubmed	TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.	SRP72 HMGN2 MACROH2A1 RPS3A CHD5 NGDN	2.01e-04	949	32	6	36574265
Pubmed	CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality.	ZNF512B SRP72 RPS3A CHD5 NGDN	2.14e-04	605	32	5	28977666
Pubmed	Actin-related protein2/3 complex regulates tight junctions and terminal differentiation to promote epidermal barrier formation.	HBEGF AREG	2.24e-04	24	32	2	24043783
Pubmed	Interactions of the Antiviral Factor Interferon Gamma-Inducible Protein 16 (IFI16) Mediate Immune Signaling and Herpes Simplex Virus-1 Immunosuppression.	NVL SRP72 MACROH2A1 NGDN	2.37e-04	332	32	4	25693804
Pubmed	MYC Protein Interactome Profiling Reveals Functionally Distinct Regions that Cooperate to Drive Tumorigenesis.	NVL HMGN2 GTF2F1 GTF3C1	2.57e-04	339	32	4	30415952
Pubmed	Genome-wide CRISPR-Cas9 Screen Identifies Leukemia-Specific Dependence on a Pre-mRNA Metabolic Pathway Regulated by DCPS.	HMGN2 MACROH2A1 STAG2 NGDN	2.60e-04	340	32	4	29478914
Pubmed	Bulk and mosaic deletions of Egfr reveal regionally defined gliogenesis in the developing mouse forebrain.	HBEGF AREG	2.84e-04	27	32	2	36915679
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	NVL SRP72 GTF3C1 RPS3A STAG2	3.04e-04	653	32	5	22586326
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	ZNF512B MRPS33 NVL MACROH2A1 SLC39A10 RPS3A DNAJC25	3.38e-04	1487	32	7	33957083
Pubmed	SHLD2/FAM35A co-operates with REV7 to coordinate DNA double-strand break repair pathway choice.	GTF3C1 RPS3A STAG2	3.56e-04	150	32	3	30154076
Pubmed	Analysis of the Tropism of SARS-CoV-2 Based on the Host Interactome of the Spike Protein.	SRP72 HMGN2	3.75e-04	31	32	2	37939376
Pubmed	Placing the HIRA histone chaperone complex in the chromatin landscape.	UBN1 GTF3C1	3.75e-04	31	32	2	23602572
Pubmed	Analysis of Ku70 S155 Phospho-Specific BioID2 Interactome Identifies Ku Association with TRIP12 in Response to DNA Damage.	ZNF512B PHF2 GTF2F1	3.99e-04	156	32	3	37108203
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	ZNF512B PHF2 SRP72 MACROH2A1 GTF3C1 RPS3A	4.05e-04	1082	32	6	38697112
Pubmed	BPA modulates the WDR5/TET2 complex to regulate ERβ expression in eutopic endometrium and drives the development of endometriosis.	SRP72 GTF2F1 MACROH2A1 EPS8L2 METAP2	4.49e-04	711	32	5	33022573
Pubmed	WDR76 Co-Localizes with Heterochromatin Related Proteins and Rapidly Responds to DNA Damage.	SRP72 MACROH2A1 GTF3C1 STAG2	4.54e-04	394	32	4	27248496
Pubmed	Proteomic analysis of SRm160-containing complexes reveals a conserved association with cohesin.	GTF2F1 RPS3A STAG2	5.13e-04	170	32	3	16159877
Pubmed	Nuclear High Mobility Group A2 (HMGA2) Interactome Revealed by Biotin Proximity Labeling.	ZNF512B MACROH2A1	5.35e-04	37	32	2	36835656
Pubmed	Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.	MRPS33 NVL SRP72 SLC39A10 NGDN	5.86e-04	754	32	5	33060197
Pubmed	Mouse model resources for vision research.	TRPM1 TULP1	6.58e-04	41	32	2	21052544
Pubmed	Delineating the HMGB1 and HMGB2 interactome in prostate and ovary epithelial cells and its relationship with cancer.	MACROH2A1 RPS3A NGDN	6.87e-04	188	32	3	29721183
Pubmed	Mapping of transcription start sites of human retina expressed genes.	GRK7 TULP1	7.92e-04	45	32	2	17286855
Pubmed	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.	SRP72 HMGN2 GTF2F1 RPS3A NGDN	7.95e-04	807	32	5	22681889
Pubmed	Comparative Interactomes of VRK1 and VRK3 with Their Distinct Roles in the Cell Cycle of Liver Cancer.	NVL MACROH2A1 RPS3A	8.82e-04	205	32	3	28927264
Interaction	H3-3A interactions	ZNF512B NVL PHF2 MACROH2A1 UBN1 GTF3C1 METAP2 RPS3A STAG2 CHD5	1.45e-07	749	32	10	int:H3-3A
Interaction	ZNF330 interactions	ZNF512B NVL PHF2 GTF2F1 MACROH2A1 GTF3C1 RPS3A STAG2	3.57e-07	446	32	8	int:ZNF330
Interaction	RPL31 interactions	ZNF512B NVL PHF2 SRP72 HMGN2 GTF2F1 METAP2 RPS3A NGDN	7.52e-07	680	32	9	int:RPL31
Interaction	RPS24 interactions	NVL PHF2 SRP72 GTF2F1 MACROH2A1 METAP2 RPS3A NGDN	1.29e-06	529	32	8	int:RPS24
Interaction	CENPA interactions	ZNF512B PHF2 HMGN2 GTF2F1 MACROH2A1 GTF3C1 STAG2	1.71e-06	377	32	7	int:CENPA
Interaction	ASF1A interactions	ZNF512B PHF2 HMGN2 GTF2F1 UBN1 GTF3C1	2.32e-06	249	32	6	int:ASF1A
Interaction	H2BC8 interactions	ZNF512B NVL PHF2 HMGN2 GTF2F1 MACROH2A1 GTF3C1 STAG2	2.43e-06	576	32	8	int:H2BC8
Interaction	RPL13A interactions	NVL SRP72 GTF2F1 MACROH2A1 METAP2 RPS3A DNAJC25 NGDN	2.95e-06	591	32	8	int:RPL13A
Interaction	RPL11 interactions	NVL SRP72 MACROH2A1 METAP2 RPS3A STAG2 SURF2 NGDN	6.08e-06	652	32	8	int:RPL11
Interaction	H2BC12 interactions	CYLC1 HMGN2 MACROH2A1 AEBP1 STAG2 CHD5	1.01e-05	322	32	6	int:H2BC12
Interaction	RPL3 interactions	NVL SRP72 MACROH2A1 METAP2 RPS3A DNAJC25 SURF2 NGDN	1.28e-05	722	32	8	int:RPL3
Interaction	SMC5 interactions	ZNF512B NVL PHF2 SRP72 HMGN2 MACROH2A1 UBN1 RPS3A STAG2	1.75e-05	1000	32	9	int:SMC5
Interaction	RPL4 interactions	MRPS33 NVL SRP72 GTF3C1 METAP2 RPS3A DNAJC25 NGDN	1.93e-05	764	32	8	int:RPL4
Interaction	HNRNPU interactions	MRPS33 NVL PHF2 SRP72 GTF2F1 MACROH2A1 GTF3C1 RPS3A STAG2	2.31e-05	1035	32	9	int:HNRNPU
Interaction	NCL interactions	SRP72 GTF2F1 MACROH2A1 GTF3C1 METAP2 RPS3A DNAJC25 STAG2	2.63e-05	798	32	8	int:NCL
Interaction	H2AC17 interactions	MRPS33 SRP72 MACROH2A1 RPS3A NGDN	3.03e-05	232	32	5	int:H2AC17
Interaction	RPL23A interactions	MRPS33 NVL SRP72 HMGN2 GTF2F1 METAP2 RPS3A	3.75e-05	606	32	7	int:RPL23A
Interaction	RPL5 interactions	MRPS33 NVL SRP72 METAP2 RPS3A DNAJC25 SURF2	3.75e-05	606	32	7	int:RPL5
Interaction	H2BC4 interactions	HMGN2 MACROH2A1 AEBP1 STAG2 CHD5	5.11e-05	259	32	5	int:H2BC4
Interaction	RPS19 interactions	SRP72 GTF2F1 MACROH2A1 METAP2 RPS3A BBOF1 NGDN	5.26e-05	639	32	7	int:RPS19
Interaction	SUZ12 interactions	ZNF512B PHF2 MACROH2A1 GTF3C1 IQCD RPS3A NGDN	5.52e-05	644	32	7	int:SUZ12
Interaction	H3C1 interactions	ZNF512B SRP72 HMGN2 GTF2F1 MACROH2A1 UBN1 GTF3C1 STAG2	6.24e-05	901	32	8	int:H3C1
Interaction	RPLP0 interactions	NVL SRP72 MACROH2A1 METAP2 RPS3A DNAJC25 NGDN	6.45e-05	660	32	7	int:RPLP0
Interaction	H3-4 interactions	PHF2 HMGN2 MACROH2A1 TRPM1 IQCD CHD5	6.47e-05	448	32	6	int:H3-4
Interaction	POLR1G interactions	ZNF512B NVL PHF2 GTF2F1 GTF3C1 STAG2	1.05e-04	489	32	6	int:POLR1G
Interaction	CDC14B interactions	ZNF512B MRPS33 PHF2 GTF2F1	1.10e-04	158	32	4	int:CDC14B
Interaction	H3C3 interactions	ZNF512B PHF2 GTF3C1 METAP2 STAG2 CHD5	1.12e-04	495	32	6	int:H3C3
Interaction	APEX1 interactions	ZNF512B PHF2 HMGN2 GTF2F1 MACROH2A1 EPS8L2 GTF3C1 METAP2 STAG2	1.15e-04	1271	32	9	int:APEX1
Interaction	MECP2 interactions	ZNF512B NVL PHF2 SRP72 HMGN2 MACROH2A1 GTF3C1 METAP2 RPS3A	1.26e-04	1287	32	9	int:MECP2
Interaction	RPL18 interactions	MRPS33 NVL SRP72 METAP2 RPS3A DNAJC25	1.35e-04	512	32	6	int:RPL18
Interaction	PARP1 interactions	ZNF512B NVL PHF2 HMGN2 GTF2F1 MACROH2A1 GTF3C1 RPS3A STAG2	1.49e-04	1316	32	9	int:PARP1
Interaction	CHD3 interactions	ZNF512B SRP72 METAP2 RPS3A STAG2 CHD5 NGDN	1.52e-04	757	32	7	int:CHD3
Interaction	WDR46 interactions	NVL SRP72 RPS3A NGDN	1.56e-04	173	32	4	int:WDR46
Interaction	RPL15 interactions	NVL GTF2F1 MACROH2A1 METAP2 RPS3A DNAJC25	1.63e-04	530	32	6	int:RPL15
Interaction	RPL14 interactions	NVL SRP72 GTF2F1 METAP2 RPS3A DNAJC25	2.07e-04	554	32	6	int:RPL14
Interaction	POLR1E interactions	ZNF512B NVL PHF2 GTF2F1 GTF3C1	2.10e-04	350	32	5	int:POLR1E
Interaction	ZMYND8 interactions	ZNF512B MACROH2A1 RPS3A CHD5	2.28e-04	191	32	4	int:ZMYND8
Interaction	RPL17 interactions	MRPS33 NVL SRP72 METAP2 RPS3A NGDN	2.44e-04	571	32	6	int:RPL17
Interaction	RPS6 interactions	ZNF512B NVL PHF2 SRP72 METAP2 RPS3A NGDN	3.66e-04	874	32	7	int:RPS6
Interaction	H2BC3 interactions	CYLC1 SRP72 HMGN2 MACROH2A1 STAG2	4.16e-04	406	32	5	int:H2BC3
Interaction	RPL6 interactions	MRPS33 SRP72 GTF2F1 METAP2 RPS3A DNAJC25	4.38e-04	637	32	6	int:RPL6
Interaction	CBX3 interactions	ZNF512B HMGN2 MACROH2A1 GTF3C1 STAG2 CHD5	4.71e-04	646	32	6	int:CBX3
Interaction	RPS8 interactions	MRPS33 SRP72 HMGN2 METAP2 RPS3A NGDN	4.83e-04	649	32	6	int:RPS8
Interaction	ABT1 interactions	MRPS33 NVL SRP72 RPS3A NGDN	5.02e-04	423	32	5	int:ABT1
Interaction	RPL26L1 interactions	NVL SRP72 HMGN2 METAP2 RPS3A	5.47e-04	431	32	5	int:RPL26L1
Interaction	RPL27 interactions	MRPS33 SRP72 METAP2 RPS3A DNAJC25	5.47e-04	431	32	5	int:RPL27
Interaction	NIFK interactions	NVL SRP72 HMGN2 GTF2F1 RPS3A	5.47e-04	431	32	5	int:NIFK
Interaction	GTF3C1 interactions	MACROH2A1 UBN1 GTF3C1 STAG2	5.51e-04	241	32	4	int:GTF3C1
Interaction	MTA2 interactions	ZNF512B MACROH2A1 RPS3A STAG2 CHD5	5.70e-04	435	32	5	int:MTA2
Interaction	KDM2A interactions	ZNF512B MACROH2A1 STAG2	5.77e-04	103	32	3	int:KDM2A
Interaction	RPL22 interactions	NVL SRP72 GTF2F1 METAP2 RPS3A	6.00e-04	440	32	5	int:RPL22
Interaction	KIF21A interactions	NVL SRP72 GTF2F1	6.11e-04	105	32	3	int:KIF21A
Interaction	RPL7A interactions	NVL SRP72 METAP2 RPS3A DNAJC25 NGDN	6.13e-04	679	32	6	int:RPL7A
Interaction	RPL13 interactions	MRPS33 SRP72 GTF3C1 METAP2 RPS3A NGDN	7.19e-04	700	32	6	int:RPL13
Interaction	CCDC124 interactions	SRP72 HMGN2 METAP2	7.76e-04	114	32	3	int:CCDC124
Interaction	NEIL1 interactions	MRPS33 SRP72 RPS3A NGDN	9.15e-04	276	32	4	int:NEIL1
Interaction	ADARB1 interactions	NVL MACROH2A1 RPS3A CHD5 NGDN	9.66e-04	489	32	5	int:ADARB1
Interaction	MTA1 interactions	ZNF512B MACROH2A1 STAG2 CHD5	1.00e-03	283	32	4	int:MTA1
Interaction	RPL28 interactions	NVL SRP72 GTF3C1 METAP2 RPS3A	1.01e-03	494	32	5	int:RPL28
Interaction	AURKAIP1 interactions	MRPS33 SRP72 GTF3C1 RPS3A	1.02e-03	284	32	4	int:AURKAIP1
Interaction	RPL34 interactions	SRP72 METAP2 RPS3A DNAJC25	1.03e-03	285	32	4	int:RPL34
Interaction	SRSF6 interactions	MRPS33 NVL MACROH2A1 RPS3A NGDN	1.10e-03	503	32	5	int:SRSF6
Interaction	NRDC interactions	GTF3C1 HBEGF ANKEF1	1.11e-03	129	32	3	int:NRDC
Interaction	H2AC4 interactions	SRP72 HMGN2 MACROH2A1 GTF3C1 NMT2	1.12e-03	506	32	5	int:H2AC4
Interaction	RBBP7 interactions	ZNF512B UBN1 STAG2 CHD5 BAHCC1	1.13e-03	507	32	5	int:RBBP7
Interaction	MBD3 interactions	ZNF512B MACROH2A1 STAG2 CHD5	1.17e-03	295	32	4	int:MBD3
Interaction	RPS9 interactions	MRPS33 SRP72 METAP2 RPS3A NGDN	1.22e-03	515	32	5	int:RPS9
Interaction	ZCRB1 interactions	MACROH2A1 RPS3A SURF2	1.24e-03	134	32	3	int:ZCRB1
Interaction	LOC102724334 interactions	CYLC1 HMGN2 MACROH2A1	1.24e-03	134	32	3	int:LOC102724334
Interaction	NR2C2 interactions	PHF2 SRP72 HMGN2 MACROH2A1 UBN1 METAP2 RPS3A NGDN	1.26e-03	1403	32	8	int:NR2C2
Interaction	FOXB1 interactions	MACROH2A1 GTF3C1 STAG2	1.26e-03	135	32	3	int:FOXB1
Interaction	TOP2A interactions	CYLC1 SRP72 MACROH2A1 RPS3A GRK7	1.27e-03	520	32	5	int:TOP2A
Interaction	RPS14 interactions	NVL SRP72 METAP2 RPS3A NGDN	1.37e-03	529	32	5	int:RPS14
Interaction	DHX29 interactions	GTF2F1 METAP2 RPS3A	1.43e-03	141	32	3	int:DHX29
Interaction	ANOS1 interactions	NVL SRP72 NGDN	1.49e-03	143	32	3	int:ANOS1
Interaction	H2AC14 interactions	MRPS33 HMGN2 MACROH2A1	1.52e-03	144	32	3	int:H2AC14
Interaction	H2BC15 interactions	CYLC1 HMGN2 MACROH2A1	1.52e-03	144	32	3	int:H2BC15
Interaction	EED interactions	ZNF512B NVL MACROH2A1 EPS8L2 GTF3C1 METAP2 RPS3A STAG2	1.52e-03	1445	32	8	int:EED
Interaction	TOX3 interactions	PHF2 GTF3C1	1.57e-03	37	32	2	int:TOX3
Interaction	CHN1 interactions	GTF3C1 RPS3A	1.57e-03	37	32	2	int:CHN1
GeneFamily	Dynein regulatory complex	IQCD IQCA1	6.36e-05	11	20	2	981
GeneFamily	General transcription factors\|Xeroderma pigmentosum complementation groups\|DNA helicases\|ERCC excision repair associated	GTF2F1 GTF3C1	3.43e-04	25	20	2	565
GeneFamily	AAA ATPases	NVL IQCA1	1.55e-03	53	20	2	413
GeneFamily	PHD finger proteins	PHF2 CHD5	4.39e-03	90	20	2	88
Coexpression	GSE12845_IGD_NEG_BLOOD_VS_PRE_GC_TONSIL_BCELL_DN	HMGN2 MACROH2A1 UBN1 METAP2 HBEGF	3.99e-06	198	32	5	M3195
ToppCell	TCGA-Bile_Duct-Primary_Tumor\|TCGA-Bile_Duct / Sample_Type by Project: Shred V9	GTF2F1 MACROH2A1 UBN1 GTF3C1	1.24e-05	200	32	4	0350e5ffd36033099b7e32a1fdd790fff99790dc
ToppCell	TCGA-Bile_Duct-Primary_Tumor-Cholangiocarcinoma\|TCGA-Bile_Duct / Sample_Type by Project: Shred V9	GTF2F1 MACROH2A1 UBN1 GTF3C1	1.24e-05	200	32	4	ad2a6da0b1ae7a9212a3c91e5eec4baa7481d8dc
ToppCell	Severe-B_naive-8\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	AEBP1 AREG BAHCC1	1.52e-04	145	32	3	a24cad86509208bc7267b02ef1d1b0a25a2a7043
ToppCell	CV-Mild-4\|Mild / Virus stimulation, Condition and Cluster	EPS8L2 IQCD IQCA1	2.03e-04	160	32	3	2e24f8de5086b086863d3bf4d9afbd9bc93f4d5e
ToppCell	CV-Mild-4\|CV / Virus stimulation, Condition and Cluster	EPS8L2 IQCD IQCA1	2.03e-04	160	32	3	be89efeeecb0de96ce136a7a62738f15dc0badb2
ToppCell	URO-Lymphocyte-T_NK-CD4_TEM\|URO / Disease, Lineage and Cell Type	IQCA1 NMT2 TULP1	2.03e-04	160	32	3	e406f77b1c1a01d74f39ba65f99d5f8c7d75faf1
ToppCell	3'_v3-GI_small-bowel-Lymphocytic_Invariant-Inducer-like-ILC3\|GI_small-bowel / Manually curated celltypes from each tissue	MACROH2A1 AREG BAHCC1	2.26e-04	166	32	3	773673a5d0430640439845b264740bfbbdad0cb2
ToppCell	10x5'-Liver-Hematopoietic_progenitors\|Liver / Manually curated celltypes from each tissue	HMGN2 HBEGF BAHCC1	2.26e-04	166	32	3	ae967570248cf86ca3ddf55e33bcbb3e4e3684bc
ToppCell	10x5'-Liver-Hematopoietic_progenitors-Cycling_pre-Myeloid-2\|Liver / Manually curated celltypes from each tissue	HMGN2 HBEGF BAHCC1	2.26e-04	166	32	3	a176e87aa6eec81d1fb79a028f759182d11b567d
ToppCell	ICU-NoSEP-Lymphocyte-T_NK-NK_CD56bright\|ICU-NoSEP / Disease, Lineage and Cell Type	NMT2 AREG ANKEF1	2.30e-04	167	32	3	f4f188a8efca8cdd0ecfb857fe4538c10847eadd
ToppCell	LPS-antiTNF-Epithelial_alveolar-Mes-like-AT2_Progenitor\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	METAP2 SURF2 AREG	2.34e-04	168	32	3	9e7b4b9b977e90e083f5164013e79df8bc2d492e
ToppCell	Healthy_Control-Lymphoid-pDC\|Healthy_Control / Condition, Lineage, Cell class and cell subclass	EPS8L2 AEBP1 AREG	2.38e-04	169	32	3	a4e9b8b2f0338203455ba941b8f99bf4884d26f0
ToppCell	Healthy_Control-Lymphoid-pDC-\|Healthy_Control / Condition, Lineage, Cell class and cell subclass	EPS8L2 AEBP1 AREG	2.38e-04	169	32	3	338ce99897cb522b86edd603f75bc15ec4dfcda3
ToppCell	facs-Trachea-24m-Epithelial-airway_epithelial-tracheobronchial_ciliated_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	IQCA1 ANKEF1 BBOF1	2.60e-04	174	32	3	f1510b0f7771936adf29ae3572feab55db31832b
ToppCell	facs-Trachea-24m-Epithelial-airway_epithelial-tracheobronchial_ciliated_cell-ciliated_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	IQCA1 ANKEF1 BBOF1	2.60e-04	174	32	3	5d5d2fc60afff47f997751e8e9ca1367a22d19ec
ToppCell	Severe-B_naive-8\|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)	AEBP1 AREG BAHCC1	2.60e-04	174	32	3	f3f8c924420f46321bd47e2b97f18c7241541599
ToppCell	facs-Trachea-nan-18m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IQCD IQCA1 BBOF1	2.69e-04	176	32	3	ed788a5969edfd1199828ca5b0dd34e7f29c4d30
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Mesenchymal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IQCD IQCA1 ANKEF1	2.73e-04	177	32	3	e8bb4f8ecd5e283efec966b9fc2040a6152d5551
ToppCell	368C-Lymphocytic-NK_cells-NK_cell_E\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	PHF2 MACROH2A1 AREG	2.73e-04	177	32	3	946803293a7955116c80f403e99e4093e798ca3f
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Mesenchymal-Ependyma\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IQCD IQCA1 ANKEF1	2.78e-04	178	32	3	579cdc14f28b459e200ae2102e0bd4df8a2c0dcb
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Mesenchymal-ependymal_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IQCD IQCA1 ANKEF1	2.78e-04	178	32	3	b1db59344c074c7c80169fc2c5cd5fc89f3fe463
ToppCell	facs-Bladder-nan-24m-Epithelial\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPS3A HBEGF AREG	2.82e-04	179	32	3	fc9f44fb81da0d381a5141a95a005e66a0be28cc
ToppCell	facs-Bladder-nan-24m\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPS3A HBEGF AREG	2.82e-04	179	32	3	9152d92bb96e65d43de54e933494f0d08ae02c4f
ToppCell	facs-Bladder-nan-24m-Epithelial-nan\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPS3A HBEGF AREG	3.01e-04	183	32	3	268fc48ffd88e19c9dcd1af32b635256fc915742
ToppCell	CV-Moderate-4\|CV / Virus stimulation, Condition and Cluster	EPS8L2 IQCA1 DNAJC25	3.06e-04	184	32	3	90f5b447064743246b09a6c47bf561efafa15e1f
ToppCell	mild-Myeloid-mDC\|mild / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	MACROH2A1 HBEGF AREG	3.06e-04	184	32	3	8b37c00d59d9992d3b43268991da7bb94646c70e
ToppCell	control-Myeloid-Eosinophils\|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	SLC39A10 NMT2 AREG	3.06e-04	184	32	3	fad517d047e8eaeaa5bd4f311d770880568dd13c
ToppCell	CV-Moderate-4\|Moderate / Virus stimulation, Condition and Cluster	EPS8L2 IQCA1 DNAJC25	3.11e-04	185	32	3	4a3ce0c603c2ffe11f0f00775b6af4f6d9a6070a
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c06-NR4A2\|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)	MRPS33 SURF2 AREG	3.16e-04	186	32	3	ed9b1a784f67e8a297e2a10993a6d97df60581ac
ToppCell	facs-Bladder-nan-24m-Epithelial-bladder_urothelial_cell\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPS3A HBEGF AREG	3.16e-04	186	32	3	8589d55f7f778442bf31cd4eb1fdaa632f1b7ab0
ToppCell	ILEUM-non-inflamed-(1)_T_cell-(1)_T_(gd)\|(1)_T_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	IQCA1 AREG BAHCC1	3.21e-04	187	32	3	e5713a7bda53d1d5178ab4e0dbadc2292b6005bc
ToppCell	droplet-Lung-LUNG-1m-Epithelial\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPS8L2 IQCA1 BBOF1	3.21e-04	187	32	3	6288da8cdd450c58df00ebcfcc118f01fab7e610
ToppCell	CD8+_Memory_T_cell-CV-4\|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster	EPS8L2 IQCA1 DNAJC25	3.21e-04	187	32	3	9c2fc2f259fa7d3a65fb99c295ac378e03d9aa6c
ToppCell	3'-Child09-12-SmallIntestine-Hematopoietic-B_cells-DZ_GC_cell\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HMGN2 IQCD METAP2	3.26e-04	188	32	3	9a10536afa2dea34c78421d36564cfd8252afe45
ToppCell	ASK454-Endothelial-Lymphatic\|Endothelial / Donor, Lineage and Cell class of Lung cells from Dropseq	HMGN2 SLC39A10 AEBP1	3.31e-04	189	32	3	316c857dec9383823e09f966bca62d52d933b141
ToppCell	(0)_Myeloid-(01)_Dendritic_cell\|(0)_Myeloid / immune cells in Peripheral Blood (logTPM normalization)	EPS8L2 AEBP1 RPS3A	3.36e-04	190	32	3	e9507bb0c8ff3d071402731a9b8cfe1bba93fab0
ToppCell	(2)_Fibroblasts-(21)_Fibro-2\|(2)_Fibroblasts / Cell class and subclass of bone marrow stroma cells in homeostatis	AEBP1 HBEGF AREG	3.36e-04	190	32	3	d2afa08ad868acc6fce308ec21b0bf93591d4010
ToppCell	ASK428-Epithelial-Ciliated\|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq	IQCD IQCA1 BBOF1	3.41e-04	191	32	3	0c4b926a28bc94f3cf4d68a911c0a189f6ff505e
ToppCell	356C-Epithelial_cells-Epithelial-F_(Ciliated)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	IQCD IQCA1 BBOF1	3.41e-04	191	32	3	dad675251e129254955eac179c84a641a4864586
ToppCell	droplet-Bladder-nan-24m-Epithelial\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPS8L2 HBEGF AREG	3.41e-04	191	32	3	47066fda0eb1576023c1906584713d1b03e2303c
ToppCell	356C-Epithelial_cells-Epithelial-F_(Ciliated)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	IQCD IQCA1 BBOF1	3.41e-04	191	32	3	6d2cf41ee946137c039ddcc13593fc3f670afbba
ToppCell	(2)_Fibroblasts-(21)_Fibro-2\|World / Cell class and subclass of bone marrow stroma cells in homeostatis	AEBP1 HBEGF AREG	3.41e-04	191	32	3	5ee353c79055c08e8a3e2b43a0345bceb09f3890
ToppCell	10x3'2.3-week_14-16-Hematopoietic-HSC/MPP_and_pro-ELP\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	MACROH2A1 SLC39A10 BAHCC1	3.46e-04	192	32	3	38ec82aa2ec4f2c0a843e83f7fe54f6b2483ca3d
ToppCell	E15.5\|World / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	HMGN2 MACROH2A1 RPS3A	3.46e-04	192	32	3	4a0fb4ef8a9281489ffb0881421c9d691c52019c
ToppCell	ASK454-Immune-Mast_cell\|Immune / Donor, Lineage and Cell class of Lung cells from Dropseq	HMGN2 RPS3A NMT2	3.46e-04	192	32	3	01e6324146ea34785b770231b40f7a18f128f526
ToppCell	facs-Lung-24m-Epithelial\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	EPS8L2 IQCA1 AREG	3.46e-04	192	32	3	ebfd8209a7353fbccb8ca7ade14b4f25822cebd2
ToppCell	PCW_13-14-Epithelial-Epithelial_airway-epi_proximal_progenitor2_(4)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	EPS8L2 HBEGF AREG	3.46e-04	192	32	3	450baeb5c3df7a9445472530002ce38f177a333c
ToppCell	ASK454-Immune-Mast_cell\|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq	HMGN2 RPS3A NMT2	3.46e-04	192	32	3	4ab2524cce70b6a3a3dd31085b421565a7406c56
ToppCell	droplet-Bladder-nan-24m-Epithelial-basal_bladder_epithelial_cell_(Krt5+Krt14+)\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPS3A HBEGF AREG	3.52e-04	193	32	3	9d7bc71c4ae871aad057d3beb6e06c929ae17203
ToppCell	ASK440-Epithelial-Ciliated\|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq	IQCD IQCA1 BBOF1	3.52e-04	193	32	3	a0baa8be6f590b2031fede22be588715ae458e93
ToppCell	droplet-Bladder-nan-24m-Epithelial-bladder_urothelial_cell\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPS8L2 HBEGF AREG	3.52e-04	193	32	3	66dd5ea1f9ea4b6160a0b79b068a421754689312
ToppCell	BAL-Severe-Myeloid-MoAM-MoAM5-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	MACROH2A1 HBEGF AREG	3.57e-04	194	32	3	8805c90e4284a81a6c8078f2d2417ae77b4e5c63
ToppCell	BAL-Severe-Myeloid-MoAM-MoAM5\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	MACROH2A1 HBEGF AREG	3.57e-04	194	32	3	86d52467b05a0018517377c9c441245501f71d91
ToppCell	ASK440-Epithelial-Ciliated\|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq	IQCD IQCA1 BBOF1	3.57e-04	194	32	3	c84a7fa94fb06e08aae04db56c8c313b0afde1d7
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	EPS8L2 IQCA1 AEBP1	3.57e-04	194	32	3	8ddcaaf24cee6e30d5be52c0cbf778cfba309c53
ToppCell	BAL-Severe-Myeloid-MoAM-MoAM5-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	MACROH2A1 HBEGF AREG	3.57e-04	194	32	3	c53478057674d70b79df8a3f476d15dea1925753
ToppCell	BAL-Severe-Myeloid-MoAM-MoAM5\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	MACROH2A1 HBEGF AREG	3.57e-04	194	32	3	2ab3f75b795a0ee4fe0f8eeba33093fcc77935f5
ToppCell	IIF-Myeloid-cDC\|IIF / Disease, Lineage and Cell Type	MACROH2A1 HBEGF AREG	3.62e-04	195	32	3	81225852a5827e973cb3b1da5c41e93d5407ecb6
ToppCell	Severe_COVID-19-Myeloid-MoAM5\|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）	MACROH2A1 HBEGF AREG	3.62e-04	195	32	3	6d768454ed630e586431535400507074eea76dd1
ToppCell	metastatic_Brain-Myeloid_cells-CD163+CD14+_DCs\|Myeloid_cells / Location, Cell class and cell subclass	RPS3A HBEGF AREG	3.62e-04	195	32	3	79fd13a7dd9f07f86bcab280c0be1899a692fab2
ToppCell	ASK452\|World / Donor, Lineage and Cell class of Lung cells from Dropseq	AEBP1 HBEGF AREG	3.62e-04	195	32	3	7efd9d3a3f5e7dfe9698a4143ce4a0f9bf3a862c
ToppCell	metastatic_Lymph_Node-Myeloid_cells-CD163+CD14+_DCs\|Myeloid_cells / Location, Cell class and cell subclass	HMGN2 RPS3A AREG	3.62e-04	195	32	3	7fb5c0911ff09580515d1a1827d7249d6242630c
ToppCell	myeloid-cDC\|World / Lineage and Cell class	MACROH2A1 HBEGF AREG	3.68e-04	196	32	3	60258111945ee823f325bff032049c60377206d1
ToppCell	critical-Epithelial-Ciliated\|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	IQCD IQCA1 BBOF1	3.68e-04	196	32	3	27b855c6e1ae44f16db998cf0e81bd686b9cee7e
ToppCell	ILEUM-inflamed-(3)_DC2\|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	MACROH2A1 HBEGF AREG	3.68e-04	196	32	3	0a7f77ed4ea3afdd9ad8a2d2c5df83778be5197b
ToppCell	control-Others-CD34+_GATA2+_cells\|Others / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	SRP72 METAP2 RPS3A	3.68e-04	196	32	3	25994ca143701c72d2f84a3b6d348fcfa1d26a54
ToppCell	droplet-Mammary_Gland-nan-18m-Epithelial\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPS8L2 HBEGF AREG	3.68e-04	196	32	3	00f9171da4c791619e8c4c8c3c7da578c96a30ed
ToppCell	Control-B_naive-8\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	AEBP1 RPS3A BAHCC1	3.73e-04	197	32	3	925bf0d38e4ce279fa45f455546ebd199282c0df
ToppCell	(5)_Dendritic_cell-(54)_pDC\|(5)_Dendritic_cell / shred on Cell_type and subtype	EPS8L2 AEBP1 AREG	3.79e-04	198	32	3	fc6c6b60dddd7f2f997af0f87fae33f1c23f34a8
ToppCell	LPS_only-Epithelial_airway-airway_epithelial-Ciliated\|LPS_only / Treatment groups by lineage, cell group, cell type	IQCD IQCA1 BBOF1	3.79e-04	198	32	3	6d90b541fde357fbb40f8f7d4e8628a48b679718
ToppCell	ILEUM-non-inflamed-(3)_DC2\|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	MACROH2A1 HBEGF AREG	3.79e-04	198	32	3	34157b3ff2c4867cacde38810999fac279051bc8
ToppCell	distal-Epithelial-Ciliated-1\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	IQCD IQCA1 BBOF1	3.79e-04	198	32	3	d30d6c6a0a78b7571318b5b2a0186df96dd0f5a9
ToppCell	10x_3'_v3-bone_marrow_(10x_3'_v3)-myeloid-myeloid_granulocytic-granulocyte\|bone_marrow_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	HMGN2 MACROH2A1 BAHCC1	3.79e-04	198	32	3	2e669da80363163b806f23a645474d482797ae5d
ToppCell	10x5'v1-week_12-13-Lymphocytic_B-B_lineage\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	HMGN2 MACROH2A1 AEBP1	3.85e-04	199	32	3	ea75804c34989c99aab542e6d72617ed144819b6
ToppCell	myeloid-Dendritic_cell-Conventional_dendritic_cell\|Dendritic_cell / Lineage, cell class and subclass	MACROH2A1 HBEGF AREG	3.85e-04	199	32	3	688fc273c51a957e2e1f2c7d273376bd7971139d
ToppCell	(10)_Ciliated-(2)_GFP_FOXI1\|(10)_Ciliated / shred by cell type by condition	MACROH2A1 STAG2 BBOF1	3.85e-04	199	32	3	61b1ed2db71b96157b92b7535d1955a4033098da
ToppCell	medial-Epithelial-Ciliated-2\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	IQCD IQCA1 BBOF1	3.85e-04	199	32	3	526002f16bbf61cf086278d45a401cc0b0b757a8
ToppCell	10x5'v1-week_12-13-Lymphocytic_B\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	HMGN2 MACROH2A1 AEBP1	3.85e-04	199	32	3	713dfd8552635645db5e0b5721c64e5c9b4aa06c
ToppCell	(05)_Secretory-(2)_GFP_FOXI1\|(05)_Secretory / shred by cell type by condition	MACROH2A1 STAG2 AREG	3.85e-04	199	32	3	d72d87e1e530ed894c0ad5e7b5b2b1d6b59fa098
ToppCell	medial-Epithelial-Ciliated\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	IQCD IQCA1 BBOF1	3.85e-04	199	32	3	a2daa42b100c422dc8c04fb7d2ebf54293eef574
ToppCell	distal-Epithelial-Ciliated\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	IQCD IQCA1 BBOF1	3.85e-04	199	32	3	18ca031cfe702afb9bf94e03c0f3680c38e7599e
ToppCell	3'-Child04-06-SmallIntestine-Hematopoietic-B_cells-Cycling_B_cell\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HMGN2 MACROH2A1 METAP2	3.85e-04	199	32	3	8b7f84a1e385c6a9bd45a5d41f75e30819dbe32d
ToppCell	distal-2-Epithelial-Ciliated\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	IQCD IQCA1 BBOF1	3.85e-04	199	32	3	97b66b82c76c7bc1fcd7da7b94dd2aa2d4d70a60
ToppCell	distal-1-Epithelial-Ciliated\|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	IQCD IQCA1 BBOF1	3.85e-04	199	32	3	4120e4a2bc05adebe1e1e9670ed7ea55142eb83d
ToppCell	medial-2-Epithelial-Ciliated\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	IQCD IQCA1 BBOF1	3.85e-04	199	32	3	c02f04a5aa79ee0cf427f6e94b93ceab38ebbcd7
ToppCell	ILEUM-inflamed-(3)_MNP-(3)_DC2\|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	MACROH2A1 RPS3A AREG	3.85e-04	199	32	3	64b320a9e4e65071cff77980dbff7e06526819b3
ToppCell	10x5'v1-week_17-19-Lymphocytic_B-B_lineage-pre_B_progenitor\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	HMGN2 MACROH2A1 AEBP1	3.85e-04	199	32	3	be425e9cb90a73289026b1b7cb581e1c02a8985e
ToppCell	Parenchymal-10x3prime_v2-Epithelial-Epi_airway_ciliated-Ciliated\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	IQCD IQCA1 BBOF1	3.90e-04	200	32	3	9c9d2b0276c7b0709c2eeeb0673a2f58106fb14e
ToppCell	Sepsis-ICU-SEP\|Sepsis / Disease, condition lineage and cell class	HMGN2 RPS3A HBEGF	3.90e-04	200	32	3	eea2877435b6faac5e6efc5178c34eea453fb29d
ToppCell	10x5'v1-week_17-19-Lymphocytic_B-B_lineage\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	HMGN2 MACROH2A1 AEBP1	3.90e-04	200	32	3	c28d4ca51d2e2a3a22784ee251975f16a55b0297
ToppCell	Bronchial-10x5prime-Immune_Myeloid-Macrophage_other-Macrophage_intermediate\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	MACROH2A1 HBEGF AREG	3.90e-04	200	32	3	c30da72c3581d384b76c95f5989e32a36d783ef3
ToppCell	MS-IIF-Myeloid-cDC\|IIF / Disease, condition lineage and cell class	MACROH2A1 HBEGF AREG	3.90e-04	200	32	3	620a82805619d113182d59740670c9f9b93ee924
ToppCell	COVID-19-COVID-19_Severe-Lymphocyte-T/NK-NK_CD56bright\|COVID-19_Severe / Disease, condition lineage and cell class	SLC39A10 IQCA1 AREG	3.90e-04	200	32	3	12626d046a3ed8db1c9bd603ada5b97ead93e587
ToppCell	10x5'v1-week_17-19-Lymphocytic_B\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	HMGN2 MACROH2A1 AEBP1	3.90e-04	200	32	3	364f09eb9ae4913f5c80a29e943e1c0b2ffd5f93
ToppCell	Sepsis-ICU-NoSEP-Lymphocyte-T/NK-NK_CD56bright\|ICU-NoSEP / Disease, condition lineage and cell class	NMT2 AREG ANKEF1	3.90e-04	200	32	3	c2df917900872453ea17a39928e39d071a6d3339
ToppCell	Parenchymal-10x3prime_v2-Epithelial-Epi_airway_ciliated\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	IQCD IQCA1 BBOF1	3.90e-04	200	32	3	5abd6d81e1cc354484ae693fcd708d78926e75b5
ToppCell	distal-1-Hematologic-Natural_Killer\|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	GTF3C1 RPS3A AREG	3.90e-04	200	32	3	69756eba4b9b6cd5115aa7b76dfc36bb70097993
ToppCell	LPS_IL1RA-Epithelial_airway-airway_epithelial-Ciliated\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	IQCD ANKEF1 BBOF1	3.90e-04	200	32	3	4992dbf0514d674017315dbd20d91dfec0c608e9
ToppCell	Parenchymal-10x5prime-Immune_Myeloid-Macrophage_other-Macrophage_intermediate\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	MACROH2A1 HBEGF AREG	3.90e-04	200	32	3	09bac15df511687ff336c1e7a67d980c6c281f79
Disease	intrinsic cardiomyopathy (implicated_via_orthology)	MRPS33 RPS3A	2.07e-04	21	30	2	DOID:0060036 (implicated_via_orthology)
Disease	Polyarthritis, Juvenile, Rheumatoid Factor Positive	HBEGF AREG	7.84e-03	131	30	2	C4704862
Disease	Polyarthritis, Juvenile, Rheumatoid Factor Negative	HBEGF AREG	7.84e-03	131	30	2	C4552091
Disease	Juvenile arthritis	HBEGF AREG	7.84e-03	131	30	2	C3495559
Disease	Juvenile psoriatic arthritis	HBEGF AREG	7.84e-03	131	30	2	C3714758

Protein segments in the cluster

Peptide	Gene	Start	Entry
GKKKAKGKAKGSLRA	BAHCC1	1751	Q9P281
SDKPKRKKKGGKNGK	AREG	121	P15514
GVRKKIKGSKDGKKK	CHD5	251	Q8TDI0
IKGSKDGKKKGKGKK	CHD5	256	Q8TDI0
DGKKKGKGKKTAGLK	CHD5	261	Q8TDI0
KDKGKKGKKDKGPKV	AEBP1	91	Q8IUX7
RGKGKAKDKEKGKQK	IQCD	426	Q96DY2
SKKAGGKKGARKSKK	MACROH2A1	146	O75367
KEKGMGKKGKKGKFV	ANKEF1	416	Q9NU02
MPSKGKDKKKGKSKG	BBOF1	1	Q8ND07
RPVKAGKKKDKKGKK	IQCA1	461	Q86XH1
GKLKNKGSKRKKEDL	NVL	221	O15381
DGDGATGKKKKKKKK	METAP2	91	P50579
GYLGAKKKKKKQKRK	NMT2	41	O60551
AKKGEKVPKGKKGKA	HMGN2	46	P05204
KGDSKKGKKDEKKGK	CYLC1	451	P35663
RKKGKKKGKKAPAEG	EPS8L2	286	Q9H6S3
GLLKKAKEKGKNKKS	DNAJC25	196	Q9H1X3
HGKRKKKGKGLGKKR	HBEGF	91	Q99075
KLDKKRLKKKGGEKM	GRK7	221	Q8WTQ7
VKLPKGKRKKKGRKS	SLC39A10	226	Q9ULF5
KKLRGKEKPKKGEGK	MRPS33	86	Q9Y291
KKAPLAKGGRKKKKK	GTF2F1	236	P35269
AKGGRKKKKKKGSDD	GTF2F1	241	P35269
LKLKDGGKKKGKKSR	PHF2	521	O75151
NKRLTKGGKKGAKKK	RPS3A	6	P61247
KRGKKQLGSLKKKFK	SURF2	226	Q15527
QGQGDLKKKKKKKKG	SRP72	546	O76094
KKKQQQKKKKGGKGG	SRP72	656	O76094
KSNQKGKAKGKGKKK	TULP1	261	O00294
GKAKGKGKKKAKEER	TULP1	266	O00294
KKRKKIPQKGRKKKG	NGDN	296	Q8NEJ9
KTCKKGKKGPAEKGK	STAG2	41	Q8N3U4
GGRGKGKGKKKGKVK	TRPM1	426	Q7Z4N2
KKEKKKNLAGGKKRG	ZNF512B	831	Q96KM6
RKLKEGGEKIKKKKK	UBN1	191	Q9NPG3
KKDPGKKIKRKKKGE	GTF3C1	1221	Q12789
KKIKRKKKGEFPGEK	GTF3C1	1226	Q12789