Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionoxysterol binding

EPHX1 OSBPL5

4.85e-0416412GO:0008142
GeneOntologyMolecularFunctionmetalloendopeptidase activity

MMP25 ADAMTS10 ADAMTS18

1.91e-03120413GO:0004222
GeneOntologyCellularComponentextracellular matrix

MMP25 ADAMTS10 ADAMTS18 NTN4 PLAT IGF2 CILP PRG4

3.44e-05656418GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

MMP25 ADAMTS10 ADAMTS18 NTN4 PLAT IGF2 CILP PRG4

3.52e-05658418GO:0030312
GeneOntologyCellularComponentcollagen-containing extracellular matrix

ADAMTS10 NTN4 PLAT IGF2 CILP PRG4

5.46e-04530416GO:0062023
DomainSM22_calponin

VAV3 LMO7

2.55e-0411412IPR003096
DomainTSP_1

ADAMTS10 ADAMTS18 CILP

3.56e-0463413PF00090
DomainTSP1

ADAMTS10 ADAMTS18 CILP

3.90e-0465413SM00209
DomainTSP1_rpt

ADAMTS10 ADAMTS18 CILP

3.90e-0465413IPR000884
DomainTSP1

ADAMTS10 ADAMTS18 CILP

3.90e-0465413PS50092
DomainPLAC

ADAMTS10 ADAMTS18

4.21e-0414412PF08686
DomainMetalloPept_cat_dom

MMP25 ADAMTS10 ADAMTS18

7.44e-0481413IPR024079
Domain-

MMP25 ADAMTS10 ADAMTS18

7.44e-04814133.40.390.10
DomainPLAC

ADAMTS10 ADAMTS18

7.85e-0419412PS50900
DomainPLAC

ADAMTS10 ADAMTS18

7.85e-0419412IPR010909
DomainADAM_spacer1

ADAMTS10 ADAMTS18

1.16e-0323412IPR010294
DomainHemopexin-like_dom

MMP25 PRG4

1.16e-0323412IPR000585
DomainHemopexin-like_repeat

MMP25 PRG4

1.16e-0323412IPR018487
DomainADAM_spacer1

ADAMTS10 ADAMTS18

1.16e-0323412PF05986
DomainHemopexin

MMP25 PRG4

1.16e-0323412PF00045
DomainHEMOPEXIN

MMP25 PRG4

1.16e-0323412PS00024
Domain-

MMP25 PRG4

1.16e-03234122.110.10.10
DomainHEMOPEXIN_2

MMP25 PRG4

1.16e-0323412PS51642
DomainHX

MMP25 PRG4

1.16e-0323412SM00120
DomainPeptidase_M12B_ADAM-TS

ADAMTS10 ADAMTS18

1.26e-0324412IPR013273
DomainZINC_PROTEASE

MMP25 ADAMTS10 ADAMTS18

1.29e-0398413PS00142
DomainPeptidase_M12B_N

ADAMTS10 ADAMTS18

3.31e-0339412IPR002870
DomainPep_M12B_propep

ADAMTS10 ADAMTS18

3.31e-0339412PF01562
DomainDISINTEGRIN_1

ADAMTS10 ADAMTS18

3.48e-0340412PS00427
DomainReprolysin

ADAMTS10 ADAMTS18

3.48e-0340412PF01421
DomainADAM_MEPRO

ADAMTS10 ADAMTS18

3.48e-0340412PS50215
DomainDISINTEGRIN_2

ADAMTS10 ADAMTS18

3.48e-0340412PS50214
DomainPeptidase_M12B

ADAMTS10 ADAMTS18

3.48e-0340412IPR001590
DomainCYSTEINE_SWITCH

MMP25 ADAMTS18

3.65e-0341412PS00546
DomainDisintegrin_dom

ADAMTS10 ADAMTS18

3.65e-0341412IPR001762
DomainPept_M10_metallopeptidase

MMP25 ADAMTS18

4.01e-0343412IPR001818
DomainFERM_M

MYO15A EPB41L1

4.58e-0346412PF00373
DomainFERM_central

MYO15A EPB41L1

5.18e-0349412IPR019748
DomainFERM_domain

MYO15A EPB41L1

5.18e-0349412IPR000299
DomainFERM_1

MYO15A EPB41L1

5.39e-0350412PS00660
DomainFERM_2

MYO15A EPB41L1

5.39e-0350412PS00661
DomainFERM_3

MYO15A EPB41L1

5.39e-0350412PS50057
DomainBand_41_domain

MYO15A EPB41L1

5.39e-0350412IPR019749
DomainB41

MYO15A EPB41L1

5.39e-0350412SM00295
Pubmed

Transcription of the Human Microsomal Epoxide Hydrolase Gene (EPHX1) Is Regulated by PARP-1 and Histone H1.2. Association with Sodium-Dependent Bile Acid Transport.

EPHX1 PARP1

1.42e-06242225992604
Pubmed

Maternal and fetal genetic associations of PTGER3 and PON1 with preterm birth.

EPHX1 IL10RB PLAT CYP19A1

2.58e-067942420140262
Pubmed

Apolipoprotein M induces inhibition of inflammatory responses via the S1PR1 and DHCR24 pathways.

S1PR1 DHCR24

4.27e-06342230569161
Pubmed

Molecular genetic analysis of long QT syndrome in Norway indicating a high prevalence of heterozygous mutation carriers.

MINK1 SCN5A

1.42e-05542218752142
Pubmed

Insulin-like growth factors mediate heterotrimeric G protein-dependent ERK1/2 activation by transactivating sphingosine 1-phosphate receptors.

IGF2 S1PR1

1.42e-05542216926156
Pubmed

Spontaneous preterm birth in African Americans is associated with infection and inflammatory response gene variants.

EPHX1 IL10RB PLAT CYP19A1

1.60e-0512542419019335
Pubmed

Preterm birth in Caucasians is associated with coagulation and inflammation pathway gene variants.

EPHX1 IL10RB PLAT CYP19A1

1.76e-0512842418818748
Pubmed

Racial disparity in pathophysiologic pathways of preterm birth based on genetic variants.

EPHX1 IL10RB PLAT CYP19A1

1.76e-0512842419527514
Pubmed

Sequence and organization of the mouse poly (ADP-ribose) polymerase gene.

EPHX1 PARP1

2.13e-0564222498841
Pubmed

Aging-related loss of the chromatin protein HMGB2 in articular cartilage is linked to reduced cellularity and osteoarthritis.

PARP1 PRG4

2.13e-05642219139395
Pubmed

Polymorphisms in the estrogen receptor 1 and vitamin C and matrix metalloproteinase gene families are associated with susceptibility to lymphoma.

EPHX1 PARP1 IGF2 CYP19A1

2.57e-0514142418636124
Pubmed

Insulin-like growth factor II receptor, transforming growth factor-beta, and Cdk4 expression and the developmental epigenetics of mouse palate morphogenesis and dysmorphogenesis.

PLAT IGF2

3.97e-0584229438420
Pubmed

G9a histone methyltransferase contributes to imprinting in the mouse placenta.

IGF2 OSBPL5

5.10e-05942218039842
Pubmed

Polymorphism in the IL18 gene and epithelial ovarian cancer in non-Hispanic white women.

EPHX1 PARP1 IGF2 CYP19A1

5.33e-0517042419064572
Pubmed

Two distinct mechanisms of silencing by the KvDMR1 imprinting control region.

IGF2 OSBPL5

6.37e-051042218079696
Pubmed

Breast cancer: a candidate gene approach across the estrogen metabolic pathway.

EPHX1 CYP19A1

7.78e-051142217588204
Pubmed

A murine even-skipped homologue, Evx 1, is expressed during early embryogenesis and neurogenesis in a biphasic manner.

IGF2 OSBPL5

9.32e-05124221971786
Pubmed

Association study of detoxification genes in age related macular degeneration.

EPHX1 PARP1

9.32e-051242215774926
Pubmed

Partial loss of Ascl2 function affects all three layers of the mature placenta and causes intrauterine growth restriction.

IGF2 OSBPL5

9.32e-051242221238448
Pubmed

Insights on ADAMTS proteases and ADAMTS-like proteins from mammalian genetics.

ADAMTS10 ADAMTS18

9.32e-051242225770910
Pubmed

MCM8 interacts with DDX5 to promote R-loop resolution.

PARP1 MCM8

1.10e-041342238858601
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

AACS MCM8 NXF1 DDHD1 EPB41L1 MINK1

1.23e-0465042638777146
Pubmed

The species-specific differences in the cAMP regulation of the tissue-type plasminogen activator gene between rat, mouse and human is caused by a one-nucleotide substitution in the cAMP-responsive element of the promoters.

ADAMTS18 PLAT

1.48e-04154227543410
Pubmed

Isolation and characterization of a novel H1.2 complex that acts as a repressor of p53-mediated transcription.

PARP1 PURA

1.69e-041642218258596
Pubmed

Genetic polymorphisms of estrogen metabolizing enzyme and breast cancer risk in Thai women.

EPHX1 CYP19A1

1.69e-041642219415745
Pubmed

Gene density and transcription influence the localization of chromatin outside of chromosome territories detectable by FISH.

IGF2 OSBPL5

2.40e-041942212473685
Pubmed

Sequence and functional comparison in the Beckwith-Wiedemann region: implications for a novel imprinting centre and extended imprinting.

IGF2 OSBPL5

3.24e-042242211063728
Pubmed

Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.

EPB41L1 PURA MINK1 PPM1E

3.67e-0428142428706196
Pubmed

Upregulation of imprinted genes in mice: an insight into the intensity of gene expression and the evolution of genomic imprinting.

IGF2 OSBPL5

3.86e-042442220168089
Pubmed

Microarray expression profiling of tissues from mice with uniparental duplications of chromosomes 7 and 11 to identify imprinted genes.

IGF2 OSBPL5

3.86e-042442211668390
Pubmed

Fetal onset of aberrant gene expression relevant to pulmonary carcinogenesis in lung adenocarcinoma development induced by in utero arsenic exposure.

IGF2 CYP19A1

4.90e-042742217077188
Pubmed

Family-based analysis of candidate genes for polycystic ovary syndrome.

EPHX1 CYP19A1

4.90e-042742220200332
Pubmed

Determination of genetic predisposition to patent ductus arteriosus in preterm infants.

EPHX1 IGF2 DHCR24

5.15e-0412942319336370
Pubmed

Genetic variation and antioxidant response gene expression in the bronchial airway epithelium of smokers at risk for lung cancer.

EPHX1 DHCR24

5.28e-042842220689807
Pubmed

Disruption of parental-specific expression of imprinted genes in uniparental fetuses.

IGF2 OSBPL5

5.66e-042942216987518
Pubmed

Global analysis of gene expression in the developing brain of Gtf2ird1 knockout mice.

MRPL16 DHCR24

5.66e-042942221909369
Pubmed

A Large-scale genetic association study of esophageal adenocarcinoma risk.

EPHX1 PARP1 IGF2 CYP19A1

8.43e-0435142420453000
Pubmed

SR protein kinases promote splicing of nonconsensus introns.

ADAMTS18 RPL37 LMO7 NXF1

9.36e-0436142426167880
Pubmed

Allele frequencies of single nucleotide polymorphisms (SNPs) in 40 candidate genes for gene-environment studies on cancer: data from population-based Japanese random samples.

EPHX1 CYP19A1

9.74e-043842214634838
Pubmed

PTEN identified as important risk factor of chronic obstructive pulmonary disease.

EPHX1 PARP1 IGF2 CYP19A1

1.07e-0337442419625176
Pubmed

Pathway-based evaluation of 380 candidate genes and lung cancer susceptibility suggests the importance of the cell cycle pathway.

EPHX1 PARP1 IGF2 CYP19A1

1.14e-0338142418676680
Pubmed

Polymorphisms in innate immunity genes and lung cancer risk in Xuanwei, China.

EPHX1 PARP1 IGF2 CYP19A1

1.15e-0338242419170196
Cytoband12q24.31

AACS DNAH10

2.47e-038042212q24.31
GeneFamilyADAM metallopeptidases with thrombospondin type 1 motif

ADAMTS10 ADAMTS18

4.18e-041929250
GeneFamilyAnkyrin repeat domain containing|FERM domain containing

MYO15A EPB41L1

2.90e-03502921293
CoexpressionGSE369_SOCS3_KO_VS_WT_LIVER_POST_IL6_INJECTION_DN

MTMR1 VAV3 S1PR1 GNPTAB PPM1E

1.66e-05200425M5966
CoexpressionGSE8685_IL2_ACT_IL2_STARVED_VS_IL15_ACT_IL2_STARVED_CD4_TCELL_UP

EPHX1 MTMR1 TRIM36 NXF1 DDHD1

1.66e-05200425M331
CoexpressionMATZUK_STEROIDOGENESIS

CYP19A1 DHCR24

5.24e-057422M1818
CoexpressionJONES_OVARY_THECA

IGF2 CILP DHCR24

5.54e-0546423M48349
ToppCellwk_08-11-Mesenchymal-Fibroblast|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

EPHX1 PLAT RPL37 IGF2 S1PR1

1.23e-06200425482dfbbd8958b64c31568dccbffe3cc9589f876b
ToppCellmetastatic_Brain-Myeloid_cells-Undetermined|Myeloid_cells / Location, Cell class and cell subclass

EPHX1 RPL37 FCRL5 CYP19A1

1.44e-051574246ce7f2ea613e7f8e771860e8c0512274e4f54369
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

PLAT LMO7 S1PR1 DDHD1

1.84e-05167424ced6ed9b412739c6ced622523347c10295edbf53
ToppCell10x5'-GI_small-bowel-Lymphocytic_NK|GI_small-bowel / Manually curated celltypes from each tissue

ADAMTS10 ADAMTS18 S1PR1 OSBPL5

2.16e-0517442409b216f07cffd3ea2149ea95ffb5cd7219b3a98c
ToppCell10x3'2.3-week_14-16-Myeloid_neutrophil-granulo-eo/baso/mast-basophil|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

MMP25 KRBOX4 S1PR1 DHCR24

2.26e-05176424581d78811b2d99f38a2c7cc268aeb1cf932379c2
ToppCelldroplet-Limb_Muscle-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLAT RPL37 CILP PRG4

2.41e-05179424013818e173101efca7625ccd4258e60655815d73
ToppCell(3)_Chondrocytes-(32)_Chondro-prehyper-2|(3)_Chondrocytes / Cell class and subclass of bone marrow stroma cells in homeostatis

VAV3 DNAH10 LMO7 OSBPL5

2.46e-05180424708a5c89b9337e281fce4f482892a1c1766c7812
ToppCell10x3'2.3-week_12-13-Mesenchymal_fibro-stroma-endosteal_fibroblast|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

NTN4 IGF2 CILP PRG4

2.98e-05189424c392491aabe8a3e90974ab2ea123bbbe5200439d
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-stromal_related|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PLAT IGF2 MYO15A CILP

3.23e-05193424f27e2be497745098b5269aa799dd3d5f62d78ba7
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-stromal_related-ICC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PLAT IGF2 MYO15A CILP

3.23e-051934244ccf984baebbb13ae916727137ce593fda7514a2
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-skeletal_muscle_satellite_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPL37 IGF2 DHCR24 SCN5A

3.23e-051934241aa3ab528605dc7b2fec46e759c9d1ee93d59b11
ToppCell10x3'2.3-week_17-19-Mesenchymal_fibro-stroma-endosteal_fibroblast|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

NTN4 CILP PRG4 EPB41L1

3.30e-0519442469362e13158033de44f90f3773db6c0f27de8cb3
ToppCellnormal_Lung-Epithelial_cells|normal_Lung / Location, Cell class and cell subclass

EPHX1 NTN4 LMO7 DHCR24

3.37e-051954247c90d887afde5c4d63352b5171be9987e2dfca58
ToppCellPND01-Mesenchymal-Mesenchymal_myocytic|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

EPHX1 NTN4 PLAT IGF2

3.43e-05196424acbb493dbb49a33f20cf11106363f7ed51209706
ToppCellASK440-Epithelial-Type_2|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq

EPHX1 NTN4 LMO7 DHCR24

3.43e-05196424754b4202b617165c6994a0b5a9b1e486dccdd44d
ToppCell10x5'-Liver-Lymphocytic_NK-NK_CD16|Liver / Manually curated celltypes from each tissue

ADAMTS10 S1PR1 GNPTAB OSBPL5

3.43e-05196424e6d4853ccefbcd45a019cee595811f0474dcc036
ToppCell10x3'2.3-week_14-16-Mesenchymal_fibro|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

NTN4 IGF2 CILP PRG4

3.43e-05196424ee45e4de9d706ec87094e87f47d3e514539b8092
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_ILC-NK_cell|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ADAMTS10 VAV3 GNPTAB OSBPL5

3.43e-0519642478b28b263deaa43590b38597186222c6447ad25f
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NTN4 VAV3 LMO7 EPB41L1

3.43e-051964246ce74aa3f0ce3ca284b67e5a4660ffd2cc9611e0
ToppCell10x3'2.3-week_14-16-Mesenchymal_fibro-stroma|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

NTN4 IGF2 CILP PRG4

3.43e-05196424fa4a85a3cd52df0da5dfedc0e584e9df8c61ce89
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_ILC|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ADAMTS10 VAV3 GNPTAB OSBPL5

3.43e-051964243e78e307c9c991c1aadc85c61d401431cf75eaec
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c01-FCGR3A|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ADAMTS10 VAV3 GNPTAB OSBPL5

3.43e-05196424f0566f2ef96584ed6d9247b149218376fb509915
ToppCellLAM-Epithelial-AT2|LAM / Condition, Lineage and Cell class

EPHX1 NTN4 LMO7 DHCR24

3.43e-051964249165041ef3d56b4d069497fee03dd1c6e273211d
ToppCellLAM-Epithelial|LAM / Condition, Lineage and Cell class

EPHX1 NTN4 LMO7 DHCR24

3.50e-05197424e5cf07061f6d9db7f12ac17209b267373fa2270b
ToppCell(3)_Chondrocytes-(34)_Chondro-progen|(3)_Chondrocytes / Cell class and subclass of bone marrow stroma cells in homeostatis

NTN4 PLAT CILP PRG4

3.50e-05197424012c49a57f9c2a3dfa988cd3882c8c6b7ef3a5ad
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c08-IL2RB|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ADAMTS10 VAV3 GNPTAB OSBPL5

3.50e-05197424bc37b8919f98dc18c2200834405f06823d965d78
ToppCellLPS_anti-TNF-Epithelial_alveolar-AT_1-2_Progenitor-Progenitor_AT1-AT2|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

EPHX1 NTN4 LMO7 DHCR24

3.57e-0519842450852713c017217c79777c95857097103bcf2fbe
ToppCellLPS_only-Epithelial_alveolar-AT_2|LPS_only / Treatment groups by lineage, cell group, cell type

EPHX1 NTN4 LMO7 DHCR24

3.57e-05198424d087e738d69ca9853553fde46d4e7a8906439d32
ToppCellNS-critical-d_07-13|critical / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

EPHX1 LMO7 EPB41L1 DHCR24

3.57e-05198424a6e11c87b31beffb6af190c64b4ef3ee1d9dab8d
ToppCellLPS_anti-TNF-Epithelial_alveolar|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

EPHX1 NTN4 LMO7 DHCR24

3.57e-0519842453e9ed1b19cb26be58da0f37057caca0cdfaabeb
ToppCellLPS_anti-TNF-Epithelial_alveolar-AT_1-2_Progenitor|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

EPHX1 NTN4 LMO7 DHCR24

3.57e-05198424f006d68e6c51923be7772eea118546a5762e8a5e
ToppCell367C-Fibroblasts-Fibroblast-E-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

EPHX1 PLAT IGF2 CILP

3.64e-051994242aed8f4a225a3762a5e7ce99aacad9b2a37d61f1
ToppCell367C-Fibroblasts-Fibroblast-E|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

EPHX1 PLAT IGF2 CILP

3.64e-05199424c40ca26345753a2197bd9389d7323f7491c1e11d
ToppCellLPS_only-Epithelial_alveolar-AT_1-2_Progenitor-Progenitor_AT1-AT2|LPS_only / Treatment groups by lineage, cell group, cell type

EPHX1 NTN4 LMO7 DHCR24

3.64e-051994240447f8f53389fe7c6ddc04a97d86e74122ea16f4
ToppCellControl_saline-Hematopoietic_Myeloid-Granulocytic_cells-Mast-cells|Control_saline / Treatment groups by lineage, cell group, cell type

MMP25 PLAT FCRL5 MRPL16

3.72e-0520042458b25dc2d29e98354bfc8e8e161796c237c3dc23
ToppCellBiopsy_IPF-Epithelial|Biopsy_IPF / Sample group, Lineage and Cell type

EPHX1 DNAH10 LMO7 DHCR24

3.72e-0520042476f1ac00b34d07057d8da03d276438b719b46b1d
ToppCellNS-control|NS / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

EPHX1 LMO7 EPB41L1 DHCR24

3.72e-05200424ecbe89ff95d046155b984c8c150e0b9e7278f839
ToppCellwk_15-18-Mesenchymal-Fibroblast|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

EPHX1 PLAT IGF2 S1PR1

3.72e-052004244f624c3c57d1a84baa86d0830cb1b83ae110bf67
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

AACS CILP TRPV5

3.72e-041494237e295b2b82dea0754e98f8cef788e2781e5d641f
ToppCell3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PLAT FCRL5 DDHD1

3.72e-04149423aedbae2dffa1e880e5c6a146b6d5a135e7f54308
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

AACS CILP TRPV5

3.72e-04149423b4f77dc5f9d08b249fe5cd9a0acf86308c528ef4
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c13-HAVCR2|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CPOX MRPL16 PRG4

4.41e-04158423a38345ffc5a7576ce99212bcbd620864a19de1fc
ToppCellfacs-Marrow-Granulocytes-24m-Lymphocytic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPHX1 FCRL5 S1PR1

4.49e-04159423f0611a7bf15e2f7dfe828dd247650a30b3d6d44d
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c06-NR4A2|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

NTN4 CPOX S1PR1

4.49e-04159423b1d5ebd0c186b6d0279dab20d8f3b4a915acdc1f
ToppCellcritical-Epithelial-unknown_epithelial|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

IGF2 CILP NXF1

4.66e-04161423594cf3245ec065a7685db81cd8ba2cee8d42caac
ToppCellfacs-Marrow-Granulocytes-24m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPHX1 FCRL5 S1PR1

4.83e-04163423e04de78a52cc886623689a913f7852200a77605b
ToppCellfacs-Marrow-Granulocytes-24m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPHX1 FCRL5 S1PR1

4.83e-041634238509b87748ec460992ae6cedbb155e1c6f6e2e48
ToppCell390C-Fibroblasts-Fibroblast-F|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

PLAT IGF2 MINK1

4.92e-041644232957065d7f1332c5280d47be7cc342286f84be3e
ToppCell390C-Fibroblasts-Fibroblast-F-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

PLAT IGF2 MINK1

4.92e-0416442382e57d618c6e59bca4a03d31caf35b6043dfcf52
ToppCelldroplet-Liver-HEPATOCYTES-1m-Epithelial-Hepatocyte_(Pericentral_and_Periportal)|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AACS EPHX1 DHCR24

5.01e-04165423d449a568664a81d9b5538e8f409301448a32ac37
ToppCellVE-Treg-exh_CD4|VE / Condition, Cell_class and T cell subcluster

MMP25 MINK1 MDM1

5.18e-041674231036ac1ef9440612500137af9d1929672b077e4d
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-PMP-PMP_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

AACS PLAT MCM8

5.46e-04170423b1a16600754e0c12f7d39c9221f1b03135833f16
ToppCell10x5'-GI_small-bowel-Lymphocytic_NK-NK_CD16|GI_small-bowel / Manually curated celltypes from each tissue

ADAMTS10 S1PR1 OSBPL5

5.55e-041714231ee505b91f15191d294a5d491ecdf154c08b8622
ToppCellNS-critical-LOC-Lymphoid-NK|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ADAMTS10 GNPTAB OSBPL5

5.55e-04171423adda76991d9b150bb8ccf3989b7cbbf41843cf0b
ToppCellfacs-Marrow-T-cells-24m-Lymphocytic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPHX1 FCRL5 S1PR1

5.65e-04172423e04b1788f2074e66dff00cac734c8ee2cfefca6e
ToppCelldroplet-Marrow-nan-24m-Hematologic-erythroid_progenitor|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPHX1 FCRL5 S1PR1

5.65e-04172423910ec7794ea4000db4ef1e2c34e08dbc0243df2c
ToppCellEndothelial-B-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

ADAMTS18 PLAT S1PR1

5.74e-04173423a81992965137195d20fc498f750975303961a828
ToppCellControl-CD4+_T_activated|Control / Disease group and Cell class

AACS EPHX1 S1PR1

5.84e-041744232b683e81b315ad22555314433aed5681feb48da8
ToppCellfacs-Marrow-T-cells-24m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPHX1 FCRL5 S1PR1

5.84e-04174423ba909e8789a62968e90bc1c4ab614de738c130f7
ToppCellfacs-Marrow-T-cells-24m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPHX1 FCRL5 S1PR1

5.84e-041744239f7b983459d47b12a1b64e17e29b85a6ff4dc258
ToppCellMesenchymal_cells-Osteo-CAR|Mesenchymal_cells / Lineage and Cell class

LMO7 S1PR1 PPM1E

5.84e-04174423430e3cd61bc2a471959faa40e817aa4dd7d82d28
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW10-Neuronal-GABAergic_neurons|GW10 / Sample Type, Dataset, Time_group, and Cell type.

MMP25 NTN4 VAV3

5.94e-04175423d4ff1f197ad4086286e86817cbff24fa718293fc
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPHX1 FCRL5 S1PR1

5.94e-0417542382482f3fc716701bed46dc65c2044577aed15427
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPHX1 FCRL5 S1PR1

5.94e-041754235092c5159f697e20bf8aa450c414ffd997738d25
ToppCelldroplet-Lung-18m-Hematologic-myeloid-classical_monocyte_proliferating-classical_monocyte_proliferating_l2|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MMP25 CILP MDM1

6.04e-041764231510cdfcfb46ce1196a1220c07fb5f3986c81b78
ToppCelldroplet-Heart-nan-3m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS10 VAV3 IGF2

6.04e-04176423749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCell10x_5'_v1-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia_independent|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TRIM36 EPB41L1 PPM1E

6.14e-04177423f7a2e6b5e82f0565f8030696944f33c544233b94
ToppCell10x_5'_v1-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia_independent-Z|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TRIM36 EPB41L1 PPM1E

6.14e-04177423ef02ee75db36a92dda889efb6fad1193efbc4be4
ToppCellEndothelial-A-IPF_04|World / lung cells shred on cell class, cell subclass, sample id

PLAT IGF2 S1PR1

6.24e-041784232f2602b9305d55f25afa9861dd6c6347ae179337
ToppCellCOPD-Endothelial-VE_Venous|World / Disease state, Lineage and Cell class

PLAT IGF2 S1PR1

6.34e-041794239968da1adcb561d9bf167a42ab5d9de85c071c4a
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

NTN4 LMO7 DHCR24

6.34e-04179423815b959ce8721c5ded70c0ca6e318dafc691746e
ToppCell10x5'-lymph-node_spleen-Myeloid_Mac-Macrophage|lymph-node_spleen / Manually curated celltypes from each tissue

EPHX1 TRPV5 EPB41L1

6.34e-04179423b4430f633711cecf793e8e76e766a66ff1eff473
ToppCellfacs-Marrow-T_cells-18m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPHX1 LMO7 S1PR1

6.45e-04180423243622eee35d38748e945677ff115616e763e3b4
ToppCellfacs-Marrow-T_cells-18m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPHX1 LMO7 S1PR1

6.45e-041804233a8d9a71efe113d1df3933902a625c0a56812074
ToppCellE18.5-samps-Mesenchymal-Pericyte|E18.5-samps / Age Group, Lineage, Cell class and subclass

EPHX1 PLAT MINK1

6.45e-041804230b1d370db64862fe1c7ea0ffaf06d03ec82e6e70
ToppCelldroplet-Thymus-nan-24m-Lymphocytic-DN3_thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AACS MTMR1 OSBPL5

6.55e-04181423e2d03115a87f45a7ddd3ade6b9ac3843639bd41a
ToppCelldroplet-Thymus-nan-24m-Lymphocytic-Double_negative_thymocyte,_DN3_(Cd8-,_Cd4-),_some_express_pre_TCR_alpha|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AACS MTMR1 OSBPL5

6.55e-04181423d8d11ef83c4b8b6a6f5c8728e03059e45a8ad264
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS18 LMO7 PPM1E

6.55e-0418142330729f0364f719c044712a51453e22dc2c1a232b
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_1-AT1-AT2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

EPHX1 NTN4 LMO7

6.66e-04182423cc79e0cc21e2fdc4ef77f052818d27b9f707aec1
ToppCell3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IGF2 CILP PRG4

6.66e-04182423d179b5deb07c20d49eb6c58d5a65904f8921de3a
ToppCell3'-GW_trimst-2-SmallIntestine-Mesenchymal-stromal_related-ICC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PLAT MYO15A CILP

6.76e-04183423262387ee8d43b96e5f1a77c75124459a506a6172
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IGF2 CILP PRG4

6.76e-0418342306a68fa2be36448064f4668be24a5b85ad85c6e8
ToppCell5'-Adult-LymphNode-Endothelial-lymphatic_endothelial-LEC1_(ACKR4+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PLAT S1PR1 OSBPL5

6.76e-041834232d0d3b486498a7903fa9a1f48b189291da49c430
ToppCellControl-Epithelial_cells-Airway_mucous|Control / group, cell type (main and fine annotations)

PLAT CYP19A1 EPB41L1

6.76e-0418342315d24a4fb1ffe6cbafbd54fcd7dde9ddcfbe03b2
ToppCelldroplet-Marrow-nan-3m-Myeloid-Cd4_positive_Macrophages|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PARP1 VAV3 GNPTAB

6.76e-0418342392ef926e6c1de8477fa4f35d1dae85482d8009de
ToppCelldroplet-Marrow-nan-3m-Myeloid-macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PARP1 VAV3 GNPTAB

6.76e-0418342324db9cc717e651586317c6a8e03a3401651273c1
ToppCellfacs-Spleen|facs / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPL37 FCRL5 S1PR1

6.76e-04183423d8e87234d2fc2059536ed456993ab0557d118361
ToppCell3'-GW_trimst-2-SmallIntestine-Mesenchymal-stromal_related|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PLAT MYO15A CILP

6.76e-04183423c85a707acbcb582912e8ac080a36d05f91cfd7a2
ToppCellCOVID-19-Epithelial_cells-AT2|COVID-19 / group, cell type (main and fine annotations)

NTN4 LMO7 DHCR24

6.87e-04184423369b82f793deab672204558ae4e112cfa5aa9ccc
ToppCellControl-Epithelial_alveolar-AT_2|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

EPHX1 NTN4 LMO7

6.87e-0418442351e129b3fcc2df083eda05a3afe3717218b1e52b
ToppCellCOPD-Endothelial-VE_Venous|COPD / Disease state, Lineage and Cell class

PLAT IGF2 S1PR1

6.87e-0418442344d716e7ba46a1ed03f5992631289653f8fd7d5e
ToppCellCOVID-19_Severe-gd_T|COVID-19_Severe / Disease condition and Cell class

DNAH10 S1PR1 GNPTAB

6.87e-04184423791f1bcb954aadc63d4117c400537d036f68734d
ToppCellPCW_05-06-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

NTN4 VAV3 LMO7

6.87e-04184423fa4915b0498f3069fd5ef497286445528f75187e
ToppCellmetastatic_Lymph_Node-Fibroblasts-COL14A1+_matrix_FBs|metastatic_Lymph_Node / Location, Cell class and cell subclass

IGF2 CILP PRG4

6.98e-04185423506eee2c1b6e8acec3aa8b2c66868010006c4c14
ToppCellControl-Epithelial_alveolar-AT_2-Differentiating_AT2|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

EPHX1 NTN4 LMO7

6.98e-041854230d2add28ac1f4fa6de7699be009bf8391badaf4c
ToppCellControl-Epithelial_alveolar-AT_2-AT2_Progenitor|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

EPHX1 NTN4 LMO7

6.98e-041854238ca1374501eca01d8468130b74d50abfd4329fbe
ToppCell390C-Fibroblasts-Fibroblast-F|390C / Donor, Lineage, Cell class and subclass (all cells)

PLAT IGF2 CILP

6.98e-041854232c1f14f77faeee2acb388d997c5a27a7fef79be1
ToppCellCOVID-19-Epithelial_cells-Airway_club|COVID-19 / group, cell type (main and fine annotations)

NTN4 LMO7 DHCR24

6.98e-04185423cfe6fd73d817e173fe803bc1683c291d9bcb8608
ToppCell390C-Fibroblasts-Fibroblast-F-|390C / Donor, Lineage, Cell class and subclass (all cells)

PLAT IGF2 CILP

6.98e-0418542337db8e0b1f59274227f6fc2362167eb44bd080ef
ToppCellfacs-Limb_Muscle-Muscle_Diaphragm-18m-Mesenchymal-mesenchymal_stem_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLAT CILP PRG4

7.09e-04186423a66da8453bb78f7e9f5f59452b3c50ae679d83c3
DrugTCAT

PARP1 HBP1 IGF2

2.99e-0616413CID000013153
Drugsteffimycin

PLAT CYP19A1

3.16e-062412CID000066363
Drug4-oxazolidinone

PLAT CYP19A1

3.16e-062412CID000637590
DrugTpTpT

PARP1 PLAT CYP19A1 SCN5A

8.52e-0672414CID006441083
Drugbis-amidinium derivative of hoechst 33258

EPHX1 IL10RB MDM1 SCN5A

2.35e-0593414CID000449422
DiseaseAtherogenesis

PARP1 PLAT IGF2

7.67e-0559413C1563937
DiseaseAtherosclerosis

PARP1 PLAT IGF2

7.67e-0559413C0004153
DiseaseBrain Ischemia

IL10RB PARP1 PLAT

8.06e-0560413C0007786
DiseaseCerebral Ischemia

IL10RB PARP1 PLAT

8.06e-0560413C0917798
Diseaseperinatal necrotizing enterocolitis (biomarker_via_orthology)

IL10RB PARP1

2.53e-0417412DOID:8677 (biomarker_via_orthology)
DiseaseAnemia

PARP1 IGF2

1.03e-0334412C0002871
Diseaseosteoarthritis (is_marker_for)

HBP1 IGF2

1.09e-0335412DOID:8398 (is_marker_for)
Diseasebody weights and measures

ADAMTS10 IGF2

1.28e-0338412EFO_0004324

Protein segments in the cluster

PeptideGeneStartEntry
LGYYFPKDKRQKAWN

ERICH6B

556

Q5W0A0
KYRKAYFSKFPGIWA

AACS

506

Q86V21
FDSIPFRGKFYKWKT

ADAMTS10

616

Q9H324
KPFRGWFYQWKPYTK

ADAMTS18

661

Q8TE60
FSYKEKFPINGWKVY

MTMR1

216

Q13613
WHSKNFTKYPKKFYP

PARP1

626

P09874
YFFKGAHYWRFPKNS

MMP25

476

Q9NPA2
WPKILKISYKRSNFY

EPB41L1

321

Q9H4G0
RFIPYKGWKLYFSEV

MCM8

71

Q9UJA3
DSYLGFLPWEKKKYF

GNPTAB

886

Q3T906
FYGYQDAPWKIFLRK

MYO15A

2681

Q9UKN7
GFRFYSPQKTKWYHR

FCRL5

46

Q96RD9
SKNWFKITIPYGRKY

NXF1

116

Q9UBU9
KFLSPAQYLYKAGAW

MDM1

311

Q8TC05
KRETYKPWYKEFQGF

LMO7

436

Q8WWI1
KKWHRFRFNPKFYSF

PPM1E

676

Q8WY54
KWVRFKYPKLISYSY

EPHX1

411

P07099
PDIFFKISWLYKKYE

CYP19A1

231

P11511
SKLNSIGNYYKPWFF

DHCR24

291

Q15392
PRYPVGKFFQYDTWK

IGF2

106

P01344
WCVYKKTKYAFSPRN

IL10RB

246

Q08334
PFYVKNKGWSSFYPS

HBP1

301

O60381
QRLPKYYSWEKAFKT

KRBOX4

141

Q5JUW0
FYKEDKKTWKPFIGY

DDHD1

171

Q8NEL9
TGKAPKLASYYKYWE

DNAH10

851

Q8IVF4
WKTKKFHRPMYYFIG

S1PR1

71

P21453
LYPKFKKWCDDYFFI

CPOX

311

P36551
RWYLSGFYKKPKGIK

OSBPL5

431

Q9H0X9
YAWAPKPYHKFMAFK

MINK1

1141

Q8N4C8
SPYDLTHKGKYWGKF

MRPL16

231

Q9NX20
KGKHFWAFRVEPYSY

TRIM36

571

Q9NQ86
RSQDFGKTWKPYKYF

NTN4

146

Q9HB63
GKTWKPYKYFATNCS

NTN4

151

Q9HB63
KCGYPAKRKRKYNWS

RPL37

36

P61927
LKWVAYGFKKYFTNA

SCN5A

1256

Q14524
KYKNWPESVYFFKRG

PRG4

1251

Q92954
KATGKPRPDKYFWYH

CILP

331

O75339
SKPWCYVFKAGKYSS

PLAT

186

P00750
CSFPFKYTYGVNAWK

ZMYM2

1066

Q9UBW7
YKVWAKFGHTFCKYS

PURA

261

Q00577
LVSFKWNKYGRPYFC

TRPV5

316

Q9NQA5
AAYGYWFKGRTSPKT

SIGLEC16

56

A6NMB1
PTTDKENKKWSYGFY

VAV3

456

Q9UKW4