Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	retinoic acid binding	UGT1A10 UGT1A8 UGT1A9 RXRA	2.50e-05	28	123	4	GO:0001972
GeneOntologyMolecularFunction	carboxylic acid binding	UGT1A10 UGT1A8 UGT1A9 RXRA ACOX3 YARS2 P3H1 GRIN3B	1.18e-04	239	123	8	GO:0031406
GeneOntologyMolecularFunction	organic acid binding	UGT1A10 UGT1A8 UGT1A9 RXRA ACOX3 YARS2 P3H1 GRIN3B	1.80e-04	254	123	8	GO:0043177
GeneOntologyMolecularFunction	retinoid binding	UGT1A10 UGT1A8 UGT1A9 RXRA	2.16e-04	48	123	4	GO:0005501
GeneOntologyMolecularFunction	cytidine kinase activity	UCK1 UCK2	2.24e-04	4	123	2	GO:0043771
GeneOntologyMolecularFunction	uridine kinase activity	UCK1 UCK2	2.24e-04	4	123	2	GO:0004849
GeneOntologyMolecularFunction	isoprenoid binding	UGT1A10 UGT1A8 UGT1A9 RXRA	2.34e-04	49	123	4	GO:0019840
GeneOntologyMolecularFunction	monocarboxylic acid binding	UGT1A10 UGT1A8 UGT1A9 RXRA ACOX3	5.26e-04	107	123	5	GO:0033293
GeneOntologyMolecularFunction	protein kinase C binding	DSP UGT1A10 UGT1A8 UGT1A9	7.36e-04	66	123	4	GO:0005080
GeneOntologyMolecularFunction	fatty acid binding	UGT1A10 UGT1A8 UGT1A9 ACOX3	8.70e-04	69	123	4	GO:0005504
GeneOntologyMolecularFunction	voltage-gated monoatomic ion channel activity	CACNA1E LRRC38 KCNA7 KCND3 KCNJ3 GRIN3B	9.30e-04	182	123	6	GO:0005244
GeneOntologyMolecularFunction	voltage-gated channel activity	CACNA1E LRRC38 KCNA7 KCND3 KCNJ3 GRIN3B	9.84e-04	184	123	6	GO:0022832
GeneOntologyBiologicalProcess	estrogen catabolic process	UGT1A10 UGT1A8 UGT1A9	1.95e-06	5	121	3	GO:0006711
GeneOntologyBiologicalProcess	phenylpropanoid catabolic process	UGT1A10 UGT1A8 UGT1A9	3.89e-06	6	121	3	GO:0046271
GeneOntologyBiologicalProcess	coumarin catabolic process	UGT1A10 UGT1A8 UGT1A9	3.89e-06	6	121	3	GO:0046226
GeneOntologyBiologicalProcess	flavone metabolic process	UGT1A10 UGT1A8 UGT1A9	3.89e-06	6	121	3	GO:0051552
GeneOntologyBiologicalProcess	multi-pass transmembrane protein insertion into ER membrane	NOMO1 NOMO2 NOMO3	1.61e-05	9	121	3	GO:0160063
GeneOntologyBiologicalProcess	pigment metabolic process	UGT1A10 UGT1A8 UGT1A9 FXN SLCO1A2 SLC45A2	1.92e-05	94	121	6	GO:0042440
GeneOntologyBiologicalProcess	phenylpropanoid metabolic process	UGT1A10 UGT1A8 UGT1A9	2.29e-05	10	121	3	GO:0009698
GeneOntologyBiologicalProcess	coumarin metabolic process	UGT1A10 UGT1A8 UGT1A9	2.29e-05	10	121	3	GO:0009804
GeneOntologyBiologicalProcess	flavonoid metabolic process	UGT1A10 UGT1A8 UGT1A9	5.40e-05	13	121	3	GO:0009812
GeneOntologyBiologicalProcess	CTP salvage	UCK1 UCK2	1.02e-04	3	121	2	GO:0044211
GeneOntologyBiologicalProcess	CMP biosynthetic process	UCK1 UCK2	2.03e-04	4	121	2	GO:0009224
GeneOntologyBiologicalProcess	protein insertion into membrane	NOMO1 NOMO2 GRIN3B NOMO3	2.11e-04	50	121	4	GO:0051205
GeneOntologyBiologicalProcess	cellular glucuronidation	UGT1A10 UGT1A8 UGT1A9	2.42e-04	21	121	3	GO:0052695
GeneOntologyBiologicalProcess	hormone catabolic process	UGT1A10 UGT1A8 UGT1A9	2.42e-04	21	121	3	GO:0042447
GeneOntologyCellularComponent	multi-pass translocon complex	NOMO1 NOMO2 NOMO3	1.67e-05	9	124	3	GO:0160064
GeneOntologyCellularComponent	ER membrane insertion complex	NOMO1 NOMO2 NOMO3	7.07e-05	14	124	3	GO:0072379
Domain	PH-BEACH_dom	NBEAL1 LYST NBEAL2 NSMAF	1.27e-07	8	124	4	IPR023362
Domain	-	NBEAL1 LYST NBEAL2 NSMAF	1.27e-07	8	124	4	2.30.29.40
Domain	PH_BEACH	NBEAL1 LYST NBEAL2 NSMAF	1.27e-07	8	124	4	PS51783
Domain	BEACH	NBEAL1 LYST NBEAL2 NSMAF	2.27e-07	9	124	4	PS50197
Domain	Beach	NBEAL1 LYST NBEAL2 NSMAF	2.27e-07	9	124	4	PF02138
Domain	-	NBEAL1 LYST NBEAL2 NSMAF	2.27e-07	9	124	4	1.10.1540.10
Domain	Beach	NBEAL1 LYST NBEAL2 NSMAF	2.27e-07	9	124	4	SM01026
Domain	BEACH_dom	NBEAL1 LYST NBEAL2 NSMAF	2.27e-07	9	124	4	IPR000409
Domain	DUF2012	NOMO1 NOMO2 NOMO3	1.14e-06	4	124	3	PF09430
Domain	DUF2012	NOMO1 NOMO2 NOMO3	1.14e-06	4	124	3	IPR019008
Domain	PH_BEACH	NBEAL1 LYST NBEAL2	5.63e-06	6	124	3	PF14844
Domain	Carb-bd-like_fold	NOMO1 NOMO2 NOMO3	1.56e-05	8	124	3	IPR013784
Domain	CarboxyPept_regulatory_dom	NOMO1 NOMO2 NOMO3	7.78e-05	13	124	3	IPR014766
Domain	-	NOMO1 NOMO2 NOMO3	7.78e-05	13	124	3	2.60.40.1120
Domain	PH_dom-like	ARHGAP15 NBEAL1 LYST CDC42BPB NBEAL2 MTMR2 PARP9 PLCG2 TNS1 NSMAF ARAP2	1.28e-04	426	124	11	IPR011993
Domain	PRK/URK	UCK1 UCK2	1.31e-04	3	124	2	IPR006083
Domain	PRK	UCK1 UCK2	1.31e-04	3	124	2	PF00485
Domain	CarboxyPept-like_regulatory	NOMO1 NOMO2 NOMO3	1.81e-04	17	124	3	IPR008969
Domain	Uridine_kinase-like	UCK1 UCK2	2.60e-04	4	124	2	IPR000764
Domain	UDPGT	UGT1A10 UGT1A8 UGT1A9	3.48e-04	21	124	3	PF00201
Domain	UDPGT	UGT1A10 UGT1A8 UGT1A9	3.48e-04	21	124	3	PS00375
Domain	UDP_glucos_trans	UGT1A10 UGT1A8 UGT1A9	3.48e-04	21	124	3	IPR002213
Domain	DUF4704	NBEAL1 NBEAL2	4.32e-04	5	124	2	IPR031570
Domain	DUF4704	NBEAL1 NBEAL2	4.32e-04	5	124	2	PF15787
Domain	TFR-like_dimer_dom	NAALADL2 FOLH1B	8.98e-04	7	124	2	IPR007365
Domain	PTEN_C2	TPTE TNS1	1.19e-03	8	124	2	PF10409
Domain	DHC_N1	DYNC2H1 DYNC1H1	1.19e-03	8	124	2	PF08385
Domain	PTEN_C2	TPTE TNS1	1.19e-03	8	124	2	SM01326
Domain	C2_TENSIN	TPTE TNS1	1.19e-03	8	124	2	PS51182
Domain	Tensin_lipid_phosphatase_dom	TPTE TNS1	1.19e-03	8	124	2	IPR029023
Domain	Tensin_C2-dom	TPTE TNS1	1.19e-03	8	124	2	IPR014020
Domain	Dynein_heavy_dom-1	DYNC2H1 DYNC1H1	1.19e-03	8	124	2	IPR013594
Domain	PPASE_TENSIN	TPTE TNS1	1.53e-03	9	124	2	PS51181
Domain	MFS_1	SLC18A1 SLC17A7 SLC45A2 MFSD1	1.72e-03	77	124	4	PF07690
Domain	MFS	SLC18A1 SLC17A7 SLC45A2 MFSD1	1.72e-03	77	124	4	IPR011701
Pathway	KEGG_DRUG_METABOLISM_OTHER_ENZYMES	UGT1A10 UGT1A8 UGT1A9 UCK1 HPRT1 UCK2	1.20e-06	51	96	6	M17726
Pubmed	Cooperative Regulation of Intestinal UDP-Glucuronosyltransferases 1A8, -1A9, and 1A10 by CDX2 and HNF4α Is Mediated by a Novel Composite Regulatory Element.	UGT1A10 UGT1A8 UGT1A9	4.53e-08	3	125	3	29519853
Pubmed	Recurrent NOMO1 Gene Deletion Is a Potential Clinical Marker in Early-Onset Colorectal Cancer and Is Involved in the Regulation of Cell Migration.	NOMO1 NOMO2 NOMO3	4.53e-08	3	125	3	36011023
Pubmed	Silencing of nodal modulator 1 inhibits the differentiation of P19 cells into cardiomyocytes.	NOMO1 NOMO2 NOMO3	4.53e-08	3	125	3	25576386
Pubmed	Cloning and characterization of the human UDP-glucuronosyltransferase 1A8, 1A9, and 1A10 gene promoters: differential regulation through an interior-like region.	UGT1A10 UGT1A8 UGT1A9	4.53e-08	3	125	3	12847094
Pubmed	Establishment of a conditional Nomo1 mouse model by CRISPR/Cas9 technology.	NOMO1 NOMO2 NOMO3	1.81e-07	4	125	3	31833031
Pubmed	A locus for autosomal recessive pseudoxanthoma elasticum, with penetrance of vascular symptoms in carriers, maps to chromosome 16p13.1.	NOMO1 NOMO2 NOMO3	1.81e-07	4	125	3	9267806
Pubmed	Genome-wide association meta-analysis for total serum bilirubin levels.	UGT1A10 UGT1A8 UGT1A9 SLCO1A2	2.80e-07	16	125	4	19414484
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	UBE4B RALGAPB PFKFB4 ADGRV1 NAALADL2 CDC42BPB RXRA NRP1 PACS1 KMT2C GTF2I SH3TC1 KCND3 KCNJ3 RIN2 PANK4 FOLH1B HECTD1 GOLGA4 NSMAF	3.70e-07	1489	125	20	28611215
Pubmed	Variation of hepatic glucuronidation: Novel functional polymorphisms of the UDP-glucuronosyltransferase UGT1A4.	UGT1A10 UGT1A8 UGT1A9	4.51e-07	5	125	3	15057901
Pubmed	Circadian Clock Component Rev-erbα Regulates Diurnal Rhythm of UDP-Glucuronosyltransferase 1a9 and Drug Glucuronidation in Mice.	UGT1A10 UGT1A8 UGT1A9	8.99e-07	6	125	3	32527940
Pubmed	Use of glucuronidation fingerprinting to describe and predict mono- and dihydroxyflavone metabolism by recombinant UGT isoforms and human intestinal and liver microsomes.	UGT1A10 UGT1A8 UGT1A9	8.99e-07	6	125	3	20297805
Pubmed	Assignment of the human UDP glucuronosyltransferase gene (UGT1A1) to chromosome region 2q37.	UGT1A10 UGT1A8 UGT1A9	1.57e-06	7	125	3	8467709
Pubmed	Molecular cloning of two cDNAs encoding the mouse bilirubin/phenol family of UDP-glucuronosyltransferases (mUGTBr/p).	UGT1A10 UGT1A8 UGT1A9	1.57e-06	7	125	3	8464825
Pubmed	Cyp3a11-mediated testosterone-6β-hydroxylation decreased, while UGT1a9-mediated propofol O-glucuronidation increased, in mice with diabetes mellitus.	UGT1A10 UGT1A8 UGT1A9	1.57e-06	7	125	3	27514509
Pubmed	Oligomerization of the UDP-glucuronosyltransferase 1A proteins: homo- and heterodimerization analysis by fluorescence resonance energy transfer and co-immunoprecipitation.	UGT1A10 UGT1A8 UGT1A9	2.50e-06	8	125	3	17179145
Pubmed	Alternatively spliced products of the UGT1A gene interact with the enzymatically active proteins to inhibit glucuronosyltransferase activity in vitro.	UGT1A10 UGT1A8 UGT1A9	2.50e-06	8	125	3	20610558
Pubmed	Nicalin and its binding partner Nomo are novel Nodal signaling antagonists.	NOMO1 NOMO2 NOMO3	2.50e-06	8	125	3	15257293
Pubmed	Disposition of flavonoids via enteric recycling: enzyme stability affects characterization of prunetin glucuronidation across species, organs, and UGT isoforms.	UGT1A10 UGT1A8 UGT1A9	2.50e-06	8	125	3	18052087
Pubmed	A genome-wide association study identifies UGT1A1 as a regulator of serum cell-free DNA in young adults: The Cardiovascular Risk in Young Finns Study.	UGT1A10 UGT1A8 UGT1A9	3.75e-06	9	125	3	22511988
Pubmed	Substrate-driven assembly of a translocon for multipass membrane proteins.	NOMO1 NOMO2 NOMO3	3.75e-06	9	125	3	36261522
Pubmed	Family-based genome-wide association scan of attention-deficit/hyperactivity disorder.	UGT1A10 UGT1A8 UGT1A9	3.75e-06	9	125	3	20732626
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	CUL2 NRDE2 RALGAPB ASH2L NRP1 PACS1 IBTK MOGS MARF1 SLC27A4 DNMT1 GNPAT	4.24e-06	650	125	12	38777146
Pubmed	Association of SNPs in the UGT1A gene cluster with total bilirubin and mortality in the Diabetes Heart Study.	UGT1A10 UGT1A8 UGT1A9	5.34e-06	10	125	3	23642732
Pubmed	UDP-glucuronosyltransferases.	UGT1A10 UGT1A8 UGT1A9	5.34e-06	10	125	3	11465080
Pubmed	A genome-wide association study for serum bilirubin levels and gene-environment interaction in a Chinese population.	UGT1A10 UGT1A8 UGT1A9	5.34e-06	10	125	3	23371916
Pubmed	A genome-wide association study of total bilirubin and cholelithiasis risk in sickle cell anemia.	UGT1A10 UGT1A8 UGT1A9	5.34e-06	10	125	3	22558097
Pubmed	A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.	CUL2 CNOT10 ASH2L GTF2I MOGS NOMO2 ASNS PANK4 UCK2 DYNC1H1 GNPAT	6.07e-06	560	125	11	35241646
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	CUL2 DYNC2H1 PDK3 RALGAPB ZNF622 DNAJB7 CDC42BPB NOMO1 NDUFAF1 MOGS NOMO2 P3H1 ASNS CLTA PANK4 VPS13A GOLGA4 DNMT1	6.41e-06	1487	125	18	33957083
Pubmed	Influence of drug transporters and UGT polymorphisms on pharmacokinetics of phenolic glucuronide metabolite of mycophenolic acid in Japanese renal transplant recipients.	UGT1A8 UGT1A9 SLCO1A2	7.32e-06	11	125	3	18695635
Pubmed	An ER translocon for multi-pass membrane protein biogenesis.	NOMO1 NOMO2 NOMO3	7.32e-06	11	125	3	32820719
Pubmed	Role of UDP-glucuronosyltransferase isoforms in 13-cis retinoic acid metabolism in humans.	UGT1A10 UGT1A8 UGT1A9	9.74e-06	12	125	3	20308471
Pubmed	Common variants in the SLCO1B3 locus are associated with bilirubin levels and unconjugated hyperbilirubinemia.	UGT1A10 UGT1A8 UGT1A9	9.74e-06	12	125	3	19419973
Pubmed	Thirteen UDPglucuronosyltransferase genes are encoded at the human UGT1 gene complex locus.	UGT1A10 UGT1A8 UGT1A9	9.74e-06	12	125	3	11434514
Pubmed	Systematic proteomics of the VCP-UBXD adaptor network identifies a role for UBXN10 in regulating ciliogenesis.	CUL2 DSC1 UBE4B CDC42BPB VPS13A SLC27A4 BRWD1	1.12e-05	209	125	7	26389662
Pubmed	UGT1A1 is a major locus influencing bilirubin levels in African Americans.	UGT1A10 UGT1A8 UGT1A9	1.26e-05	13	125	3	22085899
Pubmed	Genome-wide analysis of hepatic lipid content in extreme obesity.	UGT1A10 UGT1A8 UGT1A9	1.26e-05	13	125	3	25246029
Pubmed	Early VGLUT1-specific parallel fiber synaptic deficits and dysregulated cerebellar circuit in the KIKO mouse model of Friedreich ataxia.	FXN SLC17A7	1.28e-05	2	125	2	29259026
Pubmed	Generation of a mouse model for a conditional inactivation of Gtf2i allele.	GTF2I HPRT1	1.28e-05	2	125	2	27194223
Pubmed	Translational study of the whole transcriptome in rats and genetic polymorphisms in humans identifies LRP1B and VPS13A as key genes involved in tolerance to cocaine-induced motor disturbances.	LRP1B VPS13A	1.28e-05	2	125	2	33159041
Pubmed	Differences in the glucuronidation of bisphenols F and S between two homologous human UGT enzymes, 1A9 and 1A10.	UGT1A10 UGT1A9	1.28e-05	2	125	2	25547628
Pubmed	Purification, activity, and expression levels of two uridine-cytidine kinase isoforms in neuroblastoma cell lines.	UCK1 UCK2	1.28e-05	2	125	2	27906629
Pubmed	Glucuronidation: an important mechanism for detoxification of benzo[a]pyrene metabolites in aerodigestive tract tissues.	UGT1A10 UGT1A8	1.28e-05	2	125	2	11901093
Pubmed	Inhibition of microtubules and dynein rescues human immunodeficiency virus type 1 from owl monkey TRIMCyp-mediated restriction in a cellular context-specific fashion.	DYNC2H1 DYNC1H1	1.28e-05	2	125	2	25502651
Pubmed	Genetic analysis of the cytoplasmic dynein subunit families.	DYNC2H1 DYNC1H1	1.28e-05	2	125	2	16440056
Pubmed	Identification of UDP-glucuronosyltransferases responsible for the glucuronidation of darexaban, an oral factor Xa inhibitor, in human liver and intestine.	UGT1A10 UGT1A9	1.28e-05	2	125	2	22031623
Pubmed	Novel γ-sarcoglycan interactors in murine muscle membranes.	SGCG SVIL	1.28e-05	2	125	2	35065666
Pubmed	Transgenic mice for the preparation of hygromycin-resistant primary embryonic fibroblast feeder layers for embryonic stem cell selections.	HPRT1 DNMT1	1.28e-05	2	125	2	7739908
Pubmed	The pivotal role of uridine-cytidine kinases in pyrimidine metabolism and activation of cytotoxic nucleoside analogues in neuroblastoma.	UCK1 UCK2	1.28e-05	2	125	2	27239701
Pubmed	Studies on the substrate specificity of human intestinal UDP- lucuronosyltransferases 1A8 and 1A10.	UGT1A10 UGT1A8	1.28e-05	2	125	2	10497143
Pubmed	Pharmacogenetic effect of the UGT polymorphisms on mycophenolate is modified by calcineurin inhibitors.	UGT1A8 UGT1A9	1.28e-05	2	125	2	18568343
Pubmed	Phosphorylation of uridine and cytidine nucleoside analogs by two human uridine-cytidine kinases.	UCK1 UCK2	1.28e-05	2	125	2	11306702
Pubmed	Human UGT1A8 and UGT1A10 mRNA are expressed in primary human hepatocytes.	UGT1A10 UGT1A8	1.28e-05	2	125	2	17603215
Pubmed	Identification of two new mutations in the GPR98 and the PDE6B genes segregating in a Tunisian family.	PDE6B ADGRV1	1.28e-05	2	125	2	18854872
Pubmed	Characterization of two UDP glucuronosyltransferases that are predominantly expressed in human colon.	UGT1A10 UGT1A8	1.28e-05	2	125	2	9647757
Pubmed	How many and which amino acids are responsible for the large activity differences between the highly homologous UDP-glucuronosyltransferases (UGT) 1A9 and UGT1A10?	UGT1A10 UGT1A9	1.28e-05	2	125	2	20089735
Pubmed	A Natural Occurring Mouse Model with Adgrv1 Mutation of Usher Syndrome 2C and Characterization of its Recombinant Inbred Strains.	PDE6B ADGRV1	1.28e-05	2	125	2	29961073
Pubmed	Mayo Genome Consortia: a genotype-phenotype resource for genome-wide association studies with an application to the analysis of circulating bilirubin levels.	UGT1A10 UGT1A8 UGT1A9	1.60e-05	14	125	3	21646302
Pubmed	Human UDP-glucuronosyltransferases: metabolism, expression, and disease.	UGT1A10 UGT1A8 UGT1A9	1.60e-05	14	125	3	10836148
Pubmed	Multiple variable first exons: a mechanism for cell- and tissue-specific gene regulation.	UGT1A10 UGT1A8 UGT1A9	1.60e-05	14	125	3	14672974
Pubmed	The UDP glycosyltransferase gene superfamily: recommended nomenclature update based on evolutionary divergence.	UGT1A10 UGT1A8 UGT1A9	1.60e-05	14	125	3	9295054
Pubmed	KIF5B gene sequence variation and response of cardiac stroke volume to regular exercise.	CUL2 NRP1 SVIL	2.00e-05	15	125	3	18984674
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	TPTE DSP RALGAPB CDC42BPB PACS1 P3H1 SVIL CLTA VPS13A MTMR2 HARS1 TNS1 GOLGA4 DNMT1	2.60e-05	1049	125	14	27880917
Pubmed	Charcot-Marie-Tooth Hereditary Neuropathy Overview	PDK3 MTMR2 DYNC1H1 DNMT1	2.74e-05	48	125	4	20301532
Pubmed	Genome-wide association of serum bilirubin levels in Korean population.	UGT1A10 UGT1A8 UGT1A9	2.97e-05	17	125	3	20639394
Pubmed	Phase II metabolism of hesperetin by individual UDP-glucuronosyltransferases and sulfotransferases and rat and human tissue samples.	UGT1A10 UGT1A8 UGT1A9	3.56e-05	18	125	3	20056724
Pubmed	LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow.	NOMO1 NOMO2 HPRT1 ASNS PLCG2 HECTD1 DYNC1H1 NOMO3	3.64e-05	344	125	8	30333137
Pubmed	Recombinant human cytoplasmic dynein heavy chain 1 and 2: observation of dynein-2 motor activity in vitro.	DYNC2H1 DYNC1H1	3.84e-05	3	125	2	21723285
Pubmed	Neuropilin-1 promotes Hedgehog signaling through a novel cytoplasmic motif.	DYNC2H1 NRP1	3.84e-05	3	125	2	28667171
Pubmed	PDGFRA Is Not Essential for the Derivation and Maintenance of Mouse Extraembryonic Endoderm Stem Cell Lines.	HPRT1 DNMT1	3.84e-05	3	125	2	28919262
Pubmed	Glucuronidation of psilocin and 4-hydroxyindole by the human UDP-glucuronosyltransferases.	UGT1A10 UGT1A9	3.84e-05	3	125	2	20007669
Pubmed	Genetic polymorphisms of UGT1A8, UGT1A9 and HNF-1α and gastrointestinal symptoms in renal transplant recipients taking mycophenolic acid.	UGT1A8 UGT1A9	3.84e-05	3	125	2	23721685
Pubmed	Functional significance of UDP-glucuronosyltransferase variants in the metabolism of active tamoxifen metabolites.	UGT1A10 UGT1A8	3.84e-05	3	125	2	19244109
Pubmed	Normal DNA methylation dynamics in DICER1-deficient mouse embryonic stem cells.	HPRT1 DNMT1	3.84e-05	3	125	2	22969435
Pubmed	Cytoplasmic dynein promotes HIV-1 uncoating.	DYNC2H1 DYNC1H1	3.84e-05	3	125	2	25375884
Pubmed	Raloxifene glucuronidation in liver and intestinal microsomes of humans and monkeys: contribution of UGT1A1, UGT1A8 and UGT1A9.	UGT1A8 UGT1A9	3.84e-05	3	125	2	26247833
Pubmed	The impact of UGT1A8, UGT1A9, and UGT2B7 genetic polymorphisms on the pharmacokinetic profile of mycophenolic acid after a single oral dose in healthy volunteers.	UGT1A8 UGT1A9	3.84e-05	3	125	2	17339869
Pubmed	UGT genotype may contribute to adverse events following medication with mycophenolate mofetil in pediatric kidney transplant recipients.	UGT1A8 UGT1A9	3.84e-05	3	125	2	19225446
Pubmed	Xist nucleates local protein gradients to propagate silencing across the X chromosome.	HPRT1 DNMT1	3.84e-05	3	125	2	34813726
Pubmed	Mammalian cells express three distinct dynein heavy chains that are localized to different cytoplasmic organelles.	DYNC2H1 DYNC1H1	3.84e-05	3	125	2	8666668
Pubmed	Characterization of common UGT1A8, UGT1A9, and UGT2B7 variants with different capacities to inactivate mutagenic 4-hydroxylated metabolites of estradiol and estrone.	UGT1A8 UGT1A9	3.84e-05	3	125	2	16397224
Pubmed	Cutting edge: Epstein-Barr virus transactivates the HERV-K18 superantigen by docking to the human complement receptor 2 (CD21) on primary B cells.	HPRT1 DNMT1	3.84e-05	3	125	2	16887963
Pubmed	A genome-wide assessment of variability in human serum metabolism.	UGT1A10 UGT1A8 UGT1A9	4.21e-05	19	125	3	23281178
Pubmed	Targeted inactivation of MLL3 histone H3-Lys-4 methyltransferase activity in the mouse reveals vital roles for MLL3 in adipogenesis.	ASH2L RXRA KMT2C	4.94e-05	20	125	3	19047629
Pubmed	Large-scale mapping of human protein-protein interactions by mass spectrometry.	CUL2 NRDE2 DSP CNOT10 ACTR3B CDC42BPB YARS2 KMT2C IBTK AKTIP GTF2I NDUFAF1 HPRT1 DYNC1H1 SLC27A4	6.03e-05	1284	125	15	17353931
Pubmed	Structural basis for activity regulation of MLL family methyltransferases.	KMT2E ASH2L KMT2C	6.64e-05	22	125	3	26886794
Pubmed	Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.	DSP PDK3 UGT1A10 UGT1A8 UGT1A9 SQOR ASH2L YARS2 NOMO1 NRP1 NDUFAF1 MOGS NOMO2 P3H1 NOMO3 SLC27A4	6.67e-05	1451	125	16	30550785
Pubmed	Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.	CUL2 TPTE KMT2E LRP1B CDC42BPB UBE2B KCND3 PLA2G4B KAT8 MTMR2 HARS1	6.87e-05	730	125	11	34857952
Pubmed	Faciogenital Dysplasia 5 supports cancer stem cell traits in basal-like breast cancer by enhancing EGFR stability.	CDC42BPB NOMO1 GTF2I SVIL DYNC1H1 NOMO3	6.92e-05	191	125	6	33762435
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	FAM47A DSP ZNF622 UGT1A9 KMT2C MOGS P3H1 ASNS VPS13A PKHD1 DYNC1H1	7.39e-05	736	125	11	29676528
Pubmed	Influence of uridine diphosphate (UDP)-glucuronosyltransferases and ABCC2 genetic polymorphisms on the pharmacokinetics of mycophenolic acid and its metabolites in Chinese renal transplant recipients.	UGT1A8 UGT1A9	7.65e-05	4	125	2	18946804
Pubmed	Adenylyl cyclase 6 plays a minor role in the mouse inner ear and retina.	PDE6B ADGRV1	7.65e-05	4	125	2	37127773
Pubmed	Population pharmacokinetics and pharmacogenetics of mycophenolic acid following administration of mycophenolate mofetil in de novo pediatric renal-transplant patients.	UGT1A8 UGT1A9	7.65e-05	4	125	2	20147615
Pubmed	Dnmt1 activity is dispensable in δ-cells but is essential for α-cell homeostasis.	HPRT1 DNMT1	7.65e-05	4	125	2	28119131
Pubmed	Irinotecan pharmacokinetics/pharmacodynamics and UGT1A genetic polymorphisms in Japanese: roles of UGT1A16 and 28.	UGT1A10 UGT1A9	7.65e-05	4	125	2	17558305
Pubmed	Genetic polymorphisms of UGT1A8, UGT1A9, UGT2B7 and ABCC2 in Chinese renal transplant recipients and a comparison with other ethnic populations.	UGT1A8 UGT1A9	7.65e-05	4	125	2	23700788
Pubmed	Chromosomal mapping of a human phenol UDP-glucuronosyltransferase, GNT1.	UGT1A10 UGT1A9	7.65e-05	4	125	2	2108603
Pubmed	The testicular soma of Tsc22d3 knockout mice supports spermatogenesis and germline transmission from spermatogonial stem cell lines upon transplantation.	HPRT1 DNMT1	7.65e-05	4	125	2	31001916
Pubmed	Gamma-sarcoglycan is required for the response of archvillin to mechanical stimulation in skeletal muscle.	SGCG SVIL	7.65e-05	4	125	2	25605665
Pubmed	Action of TFII-I outside the nucleus as an inhibitor of agonist-induced calcium entry.	GTF2I PLCG2	7.65e-05	4	125	2	17023658
Pubmed	Genetic determinants influencing human serum metabolome among African Americans.	UGT1A10 UGT1A8 UGT1A9	8.68e-05	24	125	3	24625756
Cytoband	15q11.2-q21.3	NDUFAF1 PLA2G4B	2.20e-05	3	125	2	15q11.2-q21.3
Cytoband	2q37	UGT1A10 UGT1A8 UGT1A9	8.38e-05	31	125	3	2q37
GeneFamily	WD repeat domain containing\|BEACH domain containing	NBEAL1 LYST NBEAL2 NSMAF	4.87e-08	9	82	4	1230
GeneFamily	C2 tensin-type domain containing\|PTEN protein phosphatases\|Phosphoinositide phosphatases	TPTE TNS1	2.01e-04	5	82	2	902
GeneFamily	UDP glucuronosyltransferases	UGT1A10 UGT1A8 UGT1A9	4.06e-04	32	82	3	363
GeneFamily	DNAJ (HSP40) heat shock proteins\|C2 tensin-type domain containing	TPTE TNS1	5.59e-04	8	82	2	837
GeneFamily	Dyneins, cytoplasmic	DYNC2H1 DYNC1H1	1.53e-03	13	82	2	538
GeneFamily	Phospholipases\|C2 domain containing phospholipases	PLA2G4B PLCG2	3.30e-03	19	82	2	832
ToppCell	facs-Marrow-Granulocytes-3m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MGAM FMO5 PFKFB4 SQOR LYST RIN2 SVIL SLC27A4	2.98e-08	171	125	8	ab21f20ec041cbaacccbd7da4dccdb77ec8bc5c6
ToppCell	facs-Marrow-Granulocytes-3m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MGAM FMO5 PFKFB4 SQOR LYST RIN2 SVIL SLC27A4	2.98e-08	171	125	8	97ad2cfff568a9d006ab1d2e6e00946ee4e3beb3
ToppCell	LA-03._Atrial_Cardiomyocyte\|World / Chamber and Cluster_Paper	CACNA1E SGCG SLC4A3 ACOX3 KCND3 KCNJ3 SVIL	1.05e-06	188	125	7	6d249fe92d51a19da19ec14bb2262d394255d577
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL6A6 DYNC2H1 SYT7 KMT2C VPS13A DYNC1H1 GOLGA4	1.34e-06	195	125	7	3e519cffa6144a62b06124642a14c9ff39b76554
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL6A6 DYNC2H1 SYT7 KMT2C VPS13A DYNC1H1 GOLGA4	1.34e-06	195	125	7	7796ea9247f4c63762f0de8490fed08b9717fa23
ToppCell	mild\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	KMT2E KMT2C PARP9 PLCG2 DYNC1H1 GOLGA4 ARAP2	1.58e-06	200	125	7	12f1685ce8f218433068e090c9d839cd5a1910bf
ToppCell	facs-Marrow-Granulocytes-18m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MGAM PFKFB4 SQOR LYST SVIL SLC27A4	8.33e-06	169	125	6	a5964aef04093b460bbe29d5e2e7389f8fd2d46f
ToppCell	facs-Marrow-Granulocytes-18m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MGAM PFKFB4 SQOR LYST SVIL SLC27A4	8.33e-06	169	125	6	e0076aa61b4ef3f836f5750005d0469d3982eb6d
ToppCell	COVID-19-kidney-PCT-S1/S2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CNTN4 CACNA1E CDHR3 CLDN10 KCNJ3 PKHD1	1.12e-05	178	125	6	23a12d3d971b857d5be8e907334d1f6b49eeeb32
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	CNTN4 FMO5 CDHR3 CLDN10 NRP1 SLCO1A2	1.16e-05	179	125	6	d1ef7e1cb00336118e387b47f4f8120f53584391
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_B-B_plasma-male\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	CDHR3 NOMO1 NDUFAF1 MOGS PANK4 PLCG2	1.19e-05	180	125	6	8e96f8646c002768b272359af485dc0ab57e0ccd
ToppCell	COVID-19-kidney-tDL\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CNTN4 CACNA1E CDHR3 CLDN10 KCNJ3 PKHD1	1.19e-05	180	125	6	864c895b5eaedefae86f5829fa344f7b686fb59f
ToppCell	5'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DSP CDHR3 LRP1B SYT7 SLC18A1 KCNJ3	1.19e-05	180	125	6	6b1606238417490e0d9930870a7827419d1c3737
ToppCell	COVID-19-kidney-Stressed_PCT\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CNTN4 CACNA1E CDHR3 CLDN10 KCNJ3 PKHD1	1.23e-05	181	125	6	6980ea624151da32b7f537f263e40fcb87a02e81
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	AP1S3 NAALADL2 LRP1B SYT7 LYST HECTD1	1.27e-05	182	125	6	a8cc56f32efe180e8fb5d69dbe606a794b3db700
ToppCell	COVID-19-kidney-PCT-S1\|kidney / Disease (COVID-19 only), tissue and cell type	CNTN4 CDHR3 CLDN10 NRP1 VPS13A PKHD1	1.35e-05	184	125	6	51ed1ebfdef45149541917c66cbacad87072e51f
ToppCell	3'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DSP CDHR3 ADGRV1 LRP1B SYT7 SLC18A1	1.39e-05	185	125	6	eb78614c4acf8d2ce7874d7e51e16997b76127ef
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	AP1S3 NAALADL2 LRP1B LYST PKHD1 HECTD1	1.48e-05	187	125	6	77886f99c229610abd28c4c370d2c7d1536c9782
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	DYNC2H1 NAALADL2 LRP1B NBEAL2 PKHD1 HECTD1	1.48e-05	187	125	6	f124d2c699b717b7c02a1a70493f515b83dc2f4c
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	AP1S3 RBBP8 ADGRV1 NRP1 PKHD1 SLC45A2	1.53e-05	188	125	6	af740fa78542438fdff627ea1f74f4eee43316be
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	DYNC2H1 NAALADL2 LRP1B NBEAL2 PKHD1 HECTD1	1.57e-05	189	125	6	e32172ad09e93f6ac6ea2b92145b2b73003f7970
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	AP1S3 RBBP8 PFKFB4 ADGRV1 LRP1B SVIL	1.57e-05	189	125	6	8c8ca3b30d9be6c854615459a7bfba82b427c8bc
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	AP1S3 RBBP8 PFKFB4 ADGRV1 LRP1B SVIL	1.57e-05	189	125	6	5d902a4660a27548764bf04c6de152b565da835c
ToppCell	LA-03._Atrial_Cardiomyocyte\|LA / Chamber and Cluster_Paper	CACNA1E SGCG SLC4A3 KCND3 KCNJ3 SVIL	1.67e-05	191	125	6	5d1b674eb7703830b7ce8bbeac3363cabd0e6ae9
ToppCell	severe-low-quality_cells\|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	OPN1SW TXK VPS13A PLCG2 ARAP2 BRWD1	1.77e-05	193	125	6	9337bc93e3904c7fc7c93c328518bcd6453b1e8c
ToppCell	PCW_10-12-Epithelial-Epithelial_airway-epi_proximal_progenitor2_(4)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	AP1S3 DSP ADGRV1 CLDN10 PKHD1 ARAP2	1.88e-05	195	125	6	d673f8844896d5c7b76a7bc7f6b88a039f1bc263
ToppCell	severe-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	TXK KMT2C VPS13A PLCG2 GOLGA4 ARAP2	1.99e-05	197	125	6	57ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCell	3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(nasal)-Club_(nasal)_L.0.2.3.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DSP RBBP8 ATP10B KCND3 PARP9 GOLGA4	2.16e-05	200	125	6	0f6620a5baace704518d42fa2f3f90751240f7dd
ToppCell	RV-17._Lymphocyte\|RV / Chamber and Cluster_Paper	TDRD15 ARHGAP15 TMEM31 TXK ARAP2	7.19e-05	153	125	5	e1ea621184014415870e00d511386b8cc3e0833b
ToppCell	RV-17._Lymphocyte\|World / Chamber and Cluster_Paper	TDRD15 ARHGAP15 TMEM31 TXK ARAP2	7.65e-05	155	125	5	189276a3b400b2202e6681e23732e6452bfe704e
ToppCell	Posterior_cortex\|World / BrainAtlas - Mouse McCarroll V32	CNTN4 KMT2E KCNJ3 VPS13A SLC17A7	8.63e-05	159	125	5	18e9fe2efbe0bca7c3990f3b12b6f549e2c1263a
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	AP1S3 NAALADL2 LRP1B LYST HECTD1	9.42e-05	162	125	5	373513f9d0e5007b2e10a8b78d4909dcce9e3b62
ToppCell	control-low-quality_cells\|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	NBEAL1 OPN1SW KCNJ3 C9	9.66e-05	85	125	4	8be49d8fb12f5e57d3ad75f97cd03d149eb3e857
ToppCell	3'-Airway_Nasal-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell-NK_cells\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ARHGAP15 PDE6B PDK3 TXK ARAP2	9.70e-05	163	125	5	e6213900f56257fe38ac7852351bea0340294be0
ToppCell	3'-Airway_Nasal-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ARHGAP15 PDE6B PDK3 TXK ARAP2	9.70e-05	163	125	5	ed7319185c1ec384444309bb8be95691a0c2091c
ToppCell	3'-Airway_Nasal-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell-NK_cells-NK_cells_L.1.3.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ARHGAP15 PDE6B PDK3 TXK ARAP2	9.70e-05	163	125	5	ef35d7ff09aa364734fea7fdaab6260c0a3fbf09
ToppCell	PCW_07-8.5-Epithelial-Epithelial_ciliated-epi_ciliated_(14)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	ATP10B ADGRV1 CLDN10 PKHD1 DLEC1	1.03e-04	165	125	5	0c714e852f912b5749de4cb0895406673979b2e6
ToppCell	PCW_07-8.5-Epithelial-Epithelial_ciliated\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	ATP10B ADGRV1 CLDN10 PKHD1 DLEC1	1.03e-04	165	125	5	82530f96aaefe28a13bad0474bbad043f127a86c
ToppCell	5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TSNAXIP1 PDE6B DYNC2H1 CDHR3 TXK	1.15e-04	169	125	5	8bca402e144819cb9a8d431d6bf9429be2fff6d6
ToppCell	facs-Marrow-Granulocytes-18m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MGAM PFKFB4 SQOR LYST SVIL	1.15e-04	169	125	5	2341eddfedaad8cee779c37bb87f7def058588ca
ToppCell	facs-Marrow-Granulocytes-18m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MGAM PFKFB4 SQOR LYST SVIL	1.15e-04	169	125	5	94871936ccfc73b56d425373b989b87c059d4493
ToppCell	ileum\|World / shred on tissue and cell subclass	MGAM SELENOP DSP UGT1A10 GOLGA4	1.18e-04	170	125	5	9f1211bd4287620e19a59f21e6ecdca3e42e0260
ToppCell	facs-Marrow-Granulocytes\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PFKFB4 SQOR LYST SVIL SLC27A4	1.21e-04	171	125	5	1701dedf0c18751db6c9fee3d93fff150ed0e17f
ToppCell	390C-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	SELENOP TMEM31 NRP1 RIN2 DNMT1	1.28e-04	173	125	5	1f725ff16e28636b20ef26f3fa9be8b47c89378d
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Epithelial-neuro-epithelial-K_cells_(GIP+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CACNA1E MGAM DSP SLC45A2 PLCG2	1.32e-04	174	125	5	3503c7dec498597f76a86dbd5e4bb2311e743bde
ToppCell	COVID-19-kidney-Distal_Epi_Doublet_(PCT)\|kidney / Disease (COVID-19 only), tissue and cell type	CNTN4 LRP1B CLDN10 KCNJ3 PKHD1	1.39e-04	176	125	5	36f77d878a53b30465b0dea8333a3865dba75613
ToppCell	facs-Marrow-Granulocytes-3m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PFKFB4 SQOR LYST SVIL SLC27A4	1.43e-04	177	125	5	065bebd22031f143e90a407f952b444a3f8818c7
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CNTN4 FMO5 CDHR3 CLDN10 PKHD1	1.43e-04	177	125	5	2f81b26be89cc2fd8eafadaf7eae3c6ad6521462
ToppCell	facs-Marrow-Granulocytes-3m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PFKFB4 SQOR LYST SVIL SLC27A4	1.43e-04	177	125	5	eb304f20aab075bd17aa3aef819386c0e1a235bd
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DSP ATP10B ADGRV1 PLCG2 PADI1	1.50e-04	179	125	5	6e965e424eebef50f0202cff75f458be395cfca1
ToppCell	COVID-19_Convalescent-PLT_1\|World / Disease Group and Platelet Clusters	SQOR NOMO2 ASNS MARF1 TNS1	1.50e-04	179	125	5	d0f2764c6fc5d61fd69e9231b3603a80ac373f65
ToppCell	5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TSNAXIP1 DYNC2H1 CDHR3 DLEC1 GRIN3B	1.50e-04	179	125	5	5e5f1cdf4aa66868d45b74ba91e20e848a3cbaff
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TSNAXIP1 DYNC2H1 CDHR3 DLEC1 GRIN3B	1.54e-04	180	125	5	92fb01b91261b3103454924cde56add337b41844
ToppCell	droplet-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l6-17\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MGAM SGCG FPGT NDUFAF1 SH3TC1	1.54e-04	180	125	5	455d1e3ccf2ab609954f3b870e8f514ddca735f4
ToppCell	COVID-19-kidney-NK\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ARHGAP15 LYST TXK SASH3 ARAP2	1.58e-04	181	125	5	8906ee8a7a1616dfe8c3b5c73988416641213629
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CNTN4 ATP10B KCNJ3 SLCO1A2 PKHD1	1.58e-04	181	125	5	6956ecd6264f7469a25e555673bce4eb97d28f7a
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ADGRV1 NAALADL2 LRP1B SYT7 KCNJ3	1.62e-04	182	125	5	041bc819e6cf2618bf86bce8dfe2df673f392ba3
ToppCell	COVID-19-kidney-Distal_Epi_Doublet_(PCT)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CNTN4 LRP1B CLDN10 KCNJ3 PKHD1	1.62e-04	182	125	5	9d67717a6e13bcb54c1297a3e4e3abf4e51628a3
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive\|renal_medulla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	ARHGAP15 LRP1B NRP1 PACS1 SVIL	1.71e-04	184	125	5	d2bf0135eb56bb410997dccea39c5ede88a0617f
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CNTN4 MGAM FMO5 CDHR3 CLDN10	1.71e-04	184	125	5	9434731f651820b05335085582960f08fbf895de
ToppCell	NS-moderate-d_16-33-Epithelial-Ciliated\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	TSNAXIP1 DYNC2H1 CDHR3 DLEC1 GRIN3B	1.75e-04	185	125	5	5e689c2fb36ce3ac2adc8d15f67107f21cf68868
ToppCell	NS-critical-d_16-33-Epithelial-Ciliated\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	TSNAXIP1 DYNC2H1 CDHR3 DLEC1 GRIN3B	1.80e-04	186	125	5	76033438426d8f9c72cd6691a7baf92104c9f03d
ToppCell	facs-Heart-LA-24m-Mesenchymal-ventricular_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DSP SGCG SLC4A3 KCNJ3 SLC17A7	1.80e-04	186	125	5	337f768cc43db2db96ba6495b076006b1a5b0331
ToppCell	facs-Heart-LA-24m-Mesenchymal-ventricular_myocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DSP SGCG SLC4A3 KCNJ3 SLC17A7	1.80e-04	186	125	5	e378c82ef6d6cb24751515aa499a01372b3e7ccf
ToppCell	Smart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte\|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	ADGRV1 LRP1B RXRA KMT2C PKHD1	1.80e-04	186	125	5	23b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CNTN4 CDHR3 NRP1 SLCO1A2 PKHD1	1.80e-04	186	125	5	f28d72b47624b69a580b4429e2be560a26898591
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	CACNA1E MGAM CDHR3 CLDN10 PKHD1	1.80e-04	186	125	5	5784d255e9ca449d375d81938d0fbbd8a7eb44f6
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	AP1S3 NAALADL2 LRP1B SVIL PKHD1	1.84e-04	187	125	5	87b3d0478693d4c54ff06b74e5903036b9c1ee6a
ToppCell	Ciliated_cells-B-SSc-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	TSNAXIP1 DYNC2H1 CDHR3 DLEC1 GRIN3B	1.84e-04	187	125	5	2b4262c2e7c7830a976be168cee6eeb738d4feda
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	AP1S3 NAALADL2 LRP1B SVIL PKHD1	1.84e-04	187	125	5	42a1267bfc27b4460b8409ada580a87c4385841c
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	AP1S3 NAALADL2 LRP1B SVIL PKHD1	1.84e-04	187	125	5	64afdea159f5e67a1e5cea35ce898aae6e80aea5
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CNTN4 MGAM CDHR3 CLDN10 PKHD1	1.84e-04	187	125	5	dcf6475ece5b34d9d58a0d1f51c18acedb19c119
ToppCell	COVID-19-kidney-tDL\|kidney / Disease (COVID-19 only), tissue and cell type	CNTN4 CDHR3 CLDN10 NRP1 VPS13A	1.84e-04	187	125	5	d35d27ca3c0e65f92f4508e1cb98a743f44fdcdf
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CNTN4 CDHR3 CLDN10 NRP1 PKHD1	1.84e-04	187	125	5	9d77ca45f7563bd6f2a0c1be5d99d93ad30983f7
ToppCell	E18.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NRDE2 NRP1 PACS1 MOGS SH3TC1	1.84e-04	187	125	5	3699d5e71d779da922920aa3160895db187bf81b
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CNTN4 MGAM CDHR3 CLDN10 PKHD1	1.84e-04	187	125	5	f1356273bd3587b6883295edf15cb9cdb706c057
ToppCell	E18.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NRDE2 NRP1 PACS1 MOGS SH3TC1	1.84e-04	187	125	5	033ba52c0c2f9978784947098fa697368ae44834
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	AP1S3 ADGRV1 CLDN10 SLCO1A2 PKHD1	1.84e-04	187	125	5	c41a2c81dd2ceef303f39f699032aa7d6ea67cf0
ToppCell	COVID-19-kidney-DCT\|kidney / Disease (COVID-19 only), tissue and cell type	DYNC2H1 RBBP8 NAALADL2 LRP1B PKHD1	1.89e-04	188	125	5	df1fd0819d301679f3c9ea404e942e39095912eb
ToppCell	COVID-19-kidney-CD-PC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	RBBP8 NAALADL2 LRP1B KCNJ3 PKHD1	1.89e-04	188	125	5	8f9996c3f3b27efaaae8960a66af77412de9c7ef
ToppCell	facs-Heart-RA-24m-Mesenchymal-ventricular_myocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DSP SGCG SLC4A3 KCNJ3 SLC17A7	1.94e-04	189	125	5	e758b264c0a47127e33e66c395cf5a3224c7305b
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CNTN4 CDHR3 NRP1 PKHD1 TNS1	1.94e-04	189	125	5	3b48b0d220cc24d5170713d61fa91f5bb6c21841
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DYNC2H1 RBBP8 NAALADL2 LRP1B PKHD1	1.94e-04	189	125	5	975c0f079903ae36b0ffa54e86294d42ec7697de
ToppCell	Fetal_29-31_weeks-Immune-natural_killer_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ARHGAP15 LYST TXK SASH3 PLCG2	1.94e-04	189	125	5	c604da558c9f4055fb36218452463539f2a73223
ToppCell	facs-Heart-RA-24m-Mesenchymal-ventricular_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DSP SGCG SLC4A3 KCNJ3 SLC17A7	1.94e-04	189	125	5	b98f60875b1a12b2ec9dc91889298ae57f98602f
ToppCell	COVID-19-kidney-PCT-S2\|kidney / Disease (COVID-19 only), tissue and cell type	CNTN4 CDHR3 CLDN10 NRP1 PKHD1	1.94e-04	189	125	5	0be5c669b6b308bd98ddb70c84877c62a6244bbd
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CAMKK1 SYT7 VPS13A SLC17A7 ARAP2	1.98e-04	190	125	5	49e09cdb843b3d889a06a811aa5affae68b25a75
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Inner_Medullary_Collecting_Duct_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MGAM NAALADL2 LRP1B NBEAL2 PKHD1	2.03e-04	191	125	5	3e828cffa24ded19f591a7ed6c1fe88ad57fdcac
ToppCell	droplet-Mammary_Gland-nan-18m-Epithelial-luminal_epithelial_cell_of_mammary_gland\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TLCD4 SYT7 CLDN10 RIN2 SVIL	2.03e-04	191	125	5	c21e7904e06a5c90176f935f6822dbb5a1aa6755
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	CNTN4 CDHR3 CLDN10 NRP1 PKHD1	2.03e-04	191	125	5	3c464645d0e7e423f791bd63bf5bcf11f6b590d3
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	CNTN4 CDHR3 CLDN10 NRP1 PKHD1	2.03e-04	191	125	5	1c1d13144259b998d4a0e85142f7afef2ef1e63f
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	AP1S3 RBBP8 ADGRV1 LRP1B PKHD1	2.03e-04	191	125	5	2fa1b9e76a0ed2d2f0de74349e266cf4a5f51aad
ToppCell	COPD-Endothelial-VE_Arterial\|Endothelial / Disease state, Lineage and Cell class	LYST CLDN10 NOMO1 NOMO2 NOMO3	2.03e-04	191	125	5	ef16ad1c1cd2c0c0377957398c98775b62a81754
ToppCell	COVID-19-kidney-TAL\|COVID-19 / Disease (COVID-19 only), tissue and cell type	AP1S3 RBBP8 LRP1B CLDN10 PKHD1	2.03e-04	191	125	5	fe55475ce0666ab5122447a813dc2369e24947b8
ToppCell	COVID-19-kidney-CNT\|COVID-19 / Disease (COVID-19 only), tissue and cell type	RBBP8 NAALADL2 LRP1B KCNJ3 PKHD1	2.08e-04	192	125	5	760c6b9628de9693034b00c5025c5c4df94bb2e8
ToppCell	COVID-19-kidney-CNT\|kidney / Disease (COVID-19 only), tissue and cell type	DYNC2H1 RBBP8 NAALADL2 LRP1B PKHD1	2.08e-04	192	125	5	d32ae226d95b4b6adb99d14b602be09b661d4cd9
ToppCell	5'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DSP CDHR3 ADGRV1 SYT7 SLC18A1	2.08e-04	192	125	5	5692bd57093852d442400383850f416c497dcc7d
ToppCell	Control-Endothelial-VE_Arterial\|Endothelial / Disease state, Lineage and Cell class	LRP1B CLDN10 NOMO1 NOMO2 NOMO3	2.08e-04	192	125	5	7e89b9125e8b85f6be85eeccef5c8644647ab0e1
ToppCell	PCW_13-14-Epithelial-Epithelial_airway-epi_proximal_secretory_(0)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	DSP ADGRV1 CLDN10 PKHD1 ARAP2	2.13e-04	193	125	5	b38aaffbea36ef6c08ebe82675438f873c89b242
ToppCell	15\|World / Age, Tissue, Lineage and Cell class	DSP NBEAL1 CDHR3 RIN2 DLEC1	2.13e-04	193	125	5	a8ad0de955494d6f5929dc44ba46627d06d95453
Drug	ApApG	UGT1A10 UGT1A8 UGT1A9 HPRT1 SLC45A2	3.72e-08	18	125	5	CID003081975
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; HL60; HT_HG-U133A	FXN LYST RXRA SNX13 NRP1 GTF2I VNN2 KAT8 UCK2 TNS1	9.99e-08	190	125	10	2137_DN
Drug	L 654969	UGT1A10 UGT1A8 UGT1A9 KCND3 SLCO1A2 SLC45A2	1.08e-07	42	125	6	CID000005218
Drug	thymine	CACNA1E TPTE UGT1A10 UGT1A8 UGT1A9 UCK1 NRP1 KMT2C HPRT1 UCK2 SLC45A2 DNMT1	1.74e-07	315	125	12	CID000001135
Drug	AC1O5XMV	UGT1A10 UGT1A8 UGT1A9 SLC45A2	2.77e-07	11	125	4	CID006442661
Drug	4-hydroxyestrone	UGT1A10 UGT1A8 UGT1A9 HPRT1	4.14e-07	12	125	4	ctd:C026418
Drug	benzo(c)phenanthrene	OPN1SW LYST HPRT1 RECQL5 SLC45A2	9.66e-07	33	125	5	CID000009136
Drug	Methoxamine hydrochloride [61-16-5]; Down 200; 16.2uM; HL60; HT_HG-U133A	CUL2 UBE4B DYNC2H1 ACTR3B SNX13 NRP1 GTF2I VNN2 NBEAL2	1.40e-06	196	125	9	2488_DN
Drug	quercetin-3,4'-diglucoside	UGT1A10 UGT1A8 UGT1A9 SLC45A2	1.50e-06	16	125	4	CID005320835
Drug	naringenin chalcone	UGT1A10 UGT1A8 UGT1A9	1.60e-06	5	125	3	ctd:C027329
Drug	anthrarobin	UGT1A10 UGT1A8 UGT1A9	1.60e-06	5	125	3	ctd:C032186
Drug	3 beta,5 alpha,25R)- 3-hydroxyspirostan-12-one	UGT1A10 UGT1A8 UGT1A9 SLC45A2	1.95e-06	17	125	4	CID000003573
Drug	1,2,5,8-tetrahydroxy anthraquinone	UGT1A10 UGT1A8 UGT1A9	3.19e-06	6	125	3	ctd:C543211
Drug	alloin	UGT1A10 UGT1A8 UGT1A9	3.19e-06	6	125	3	ctd:C006457
Drug	2',5'-dihydroxychalcone	UGT1A10 UGT1A8 UGT1A9	3.19e-06	6	125	3	ctd:C107497
Drug	tectochrysin	MGAM UGT1A10 UGT1A8 UGT1A9	3.92e-06	20	125	4	CID005281954
Drug	AC1L1OBF	UGT1A10 UGT1A8 UGT1A9 SLC45A2	3.92e-06	20	125	4	CID000032736
Drug	entacapone	UGT1A10 UGT1A8 UGT1A9 ACOX3	3.92e-06	20	125	4	ctd:C071192
Drug	ammonia	CACNA1E MGAM SGCG UGT1A10 UGT1A8 UGT1A9 LYST SLC4A3 YARS2 ASNS SLC17A7 GRIN3B PADI1	4.69e-06	509	125	13	CID000000222
Drug	2',4'-dihydroxychalcone	UGT1A10 UGT1A8 UGT1A9	5.56e-06	7	125	3	ctd:C059354
Drug	N-methylpiperazine	UGT1A10 UGT1A8 UGT1A9 DNAJB7	5.87e-06	22	125	4	CID000053167
Drug	imipramine	FMO5 UGT1A10 UGT1A8 UGT1A9 NRP1 SLC18A1 SLC45A2 PLCG2 GRIN3B	6.18e-06	235	125	9	CID000003696
Drug	1-hydroxypyrene	UGT1A10 UGT1A8 UGT1A9 HPRT1 SLC45A2	6.52e-06	48	125	5	CID000021387
Drug	campestrol	UGT1A10 UGT1A8 UGT1A9 SLCO1A2 SLC45A2	7.23e-06	49	125	5	CID000010134
Drug	1,4-dihydroxyanthraquinone	UGT1A10 UGT1A8 UGT1A9	8.87e-06	8	125	3	ctd:C034890
Drug	glabridin	UGT1A10 UGT1A8 UGT1A9	8.87e-06	8	125	3	ctd:C107601
Drug	Dipivefrin hydrochloride [64019-93-8]; Up 200; 10.4uM; PC3; HT_HG-U133A	FMO5 PDK3 LYST UBE2B RECQL5 VPS13A PADI1 BRWD1	9.61e-06	188	125	8	7124_UP
Drug	1-bromobutane	PDE6B UCK1 OPN1SW UCK2	1.00e-05	25	125	4	CID000008002
Drug	HCG 004	UGT1A10 UGT1A8 UGT1A9 FXN ACOX3	1.17e-05	54	125	5	CID000064928
Drug	AC1MRQNQ	UGT1A10 UGT1A8 UGT1A9	1.32e-05	9	125	3	CID003522271
Drug	DHPASiU	UGT1A10 UGT1A8 UGT1A9	1.32e-05	9	125	3	CID000197602
Drug	3-iodophenol	UGT1A10 UGT1A8 UGT1A9	1.32e-05	9	125	3	CID000012272
Drug	AC1L4J7U	UGT1A10 UGT1A8 UGT1A9	1.32e-05	9	125	3	CID000186631
Drug	Chebi:32663	UGT1A10 UGT1A8 UGT1A9	1.32e-05	9	125	3	CID005460873
Drug	Guanadrel sulfate [22195-34-2]; Down 200; 7.6uM; PC3; HT_HG-U133A	UBE4B UPF3A LYST ACOX3 NRP1 GTF2I RECQL5 BRWD1	1.35e-05	197	125	8	7396_DN
Drug	DB04103	UGT1A10 UGT1A8 UGT1A9 HPRT1 SLC45A2 DYNC1H1	1.59e-05	97	125	6	CID004469987
Drug	CARMINE	UGT1A10 UGT1A8 UGT1A9 SLC45A2	1.60e-05	28	125	4	CID000014749
Drug	N-hydroxy-4-aminobiphenyl	UGT1A10 UGT1A8 UGT1A9 HPRT1	1.60e-05	28	125	4	CID000081261
Drug	ezetimibe	UGT1A10 UGT1A8 UGT1A9 LRP1B SLCO1A2 SLC45A2 SLC27A4	1.71e-05	147	125	7	CID000150311
Drug	7-hydroxy-4-trifluoromethylcoumarin	UGT1A10 UGT1A8 UGT1A9 SLC45A2	1.85e-05	29	125	4	CID005375667
Drug	Glucuronides	UGT1A10 UGT1A8 UGT1A9	1.88e-05	10	125	3	ctd:D020719
Drug	2,6-dihydroxyanthraquinone	UGT1A10 UGT1A8 UGT1A9	1.88e-05	10	125	3	ctd:C034889
Drug	PCB 156	UGT1A10 UGT1A8 UGT1A9 SLC45A2	2.43e-05	31	125	4	CID000038019
Drug	4'-HPPH	UGT1A10 UGT1A8 UGT1A9 SLC45A2	2.43e-05	31	125	4	CID000017732
Drug	4-nitrophenyl)imidazole	UGT1A10 UGT1A8 UGT1A9	2.58e-05	11	125	3	CID000123155
Drug	indole-2-carboxylic acid	UGT1A10 UGT1A8 UGT1A9 GRIN3B	2.76e-05	32	125	4	CID000072899
Drug	NNAL	UGT1A10 UGT1A8 UGT1A9 SLC45A2	2.76e-05	32	125	4	CID000104856
Drug	AC1L7UE9	UCK1 UCK2	2.99e-05	2	125	2	CID000341622
Drug	1-[butoxy(phenyl)methyl]piperidine	UCK1 UCK2	2.99e-05	2	125	2	CID000219169
Drug	Z 338	UGT1A8 UGT1A9	2.99e-05	2	125	2	ctd:C410959
Drug	geniposide	UGT1A10 UGT1A8 UGT1A9 SLC45A2	3.13e-05	33	125	4	CID000107848
Drug	gemfibrozil	UGT1A10 UGT1A8 UGT1A9 RXRA ACOX3 SLCO1A2 SLC45A2 BRWD1	3.19e-05	222	125	8	CID000003463
Drug	Ethylnitrosourea	PDE6B DYNC2H1 ADGRV1 HPRT1 PLCG2 HECTD1 DYNC1H1 DNMT1 BRWD1	3.37e-05	291	125	9	ctd:D005038
Drug	N-OH-DABZ	UGT1A10 UGT1A8 UGT1A9	3.43e-05	12	125	3	CID000051366
Drug	1-O-beta-D-glucopyranosyl-D-mannitol	UGT1A10 UGT1A8 UGT1A9	3.43e-05	12	125	3	CID000088735
Drug	2,4,6-TCB	UGT1A10 UGT1A8 UGT1A9	3.43e-05	12	125	3	CID000037247
Drug	nonanoyl-N-methylglucamide	UGT1A10 UGT1A8 UGT1A9	3.43e-05	12	125	3	CID000160090
Drug	7,7,7-triphenylheptanoic acid	UGT1A10 UGT1A8 UGT1A9	3.43e-05	12	125	3	CID000276709
Drug	ribose-5-P	PDE6B PFKFB4 UCK1 TXK HPRT1 UCK2	3.61e-05	112	125	6	CID000439167
Drug	estrone-3-glucuronide	UGT1A10 UGT1A8 UGT1A9 SLC45A2	3.97e-05	35	125	4	CID000115255
Drug	Clorgyline	SELENOP DYNC2H1 IBTK VPS13A GOLGA4 ARAP2 BRWD1	4.04e-05	168	125	7	ctd:D003010
Drug	2-hydroxyestrone	UGT1A10 UGT1A8 UGT1A9	4.44e-05	13	125	3	ctd:C024980
Drug	tritanol	UGT1A10 UGT1A8 UGT1A9	4.44e-05	13	125	3	CID000006457
Drug	5-azido-UDP-glucuronic acid	UGT1A10 UGT1A8 UGT1A9	4.44e-05	13	125	3	CID003081279
Drug	cotinine-N-glucuronide	UGT1A10 UGT1A8 UGT1A9	4.44e-05	13	125	3	CID000000411
Drug	alizarin	UGT1A10 UGT1A8 UGT1A9	4.44e-05	13	125	3	ctd:C010078
Drug	AC1L9DGV	UGT1A10 UGT1A8 UGT1A9 HPRT1	4.45e-05	36	125	4	CID000417381
Drug	acotiamide	UGT1A10 UGT1A8 UGT1A9 KCNJ3	4.97e-05	37	125	4	CID005282338
Drug	FR221647	FXN OPN1SW AKTIP CLTA	4.97e-05	37	125	4	CID005288241
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	RXRA NRP1 GTF2I KCNJ3 UCK2 NSMAF ARAP2	5.42e-05	176	125	7	1535_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	RXRA NRP1 GTF2I KCNJ3 RECQL5 UCK2 NSMAF	5.42e-05	176	125	7	2639_DN
Drug	4-methylumbelliferyl glucuronide	UGT1A10 UGT1A8 UGT1A9 SLC45A2	5.53e-05	38	125	4	CID000091553
Drug	propranolol glucuronide	UGT1A10 UGT1A8 UGT1A9	5.63e-05	14	125	3	CID000119515
Drug	PCB-61	UGT1A10 UGT1A8 UGT1A9	5.63e-05	14	125	3	CID000036401
Drug	Trichostatin A, Streptomyces sp.; Down 200; 1uM; HL60; HT_HG-U133A	LYST NRP1 GTF2I SH3TC1 UCK2 TNS1 NSMAF	5.83e-05	178	125	7	6193_DN
Drug	canola oil	COL6A6 PFKFB4 FXN NRP1 PLCG2 NSMAF	5.83e-05	122	125	6	ctd:C061996
Drug	1-phenylimidazole	UGT1A10 UGT1A8 UGT1A9 SLC45A2	6.14e-05	39	125	4	CID000081595
Drug	pyrophosphate	MGAM FMO5 FPGT PFKFB4 ACOX3 YARS2 UBE2B MOGS HPRT1 SLCO1A2 ASNS PLCG2 HARS1	6.47e-05	654	125	13	CID000001023
Drug	harmol	UGT1A10 UGT1A8 UGT1A9 SLCO1A2	6.79e-05	40	125	4	CID000068094
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	TPTE SGCG FXN NRP1 MTMR2 UCK2 NSMAF	6.94e-05	183	125	7	4770_DN
Drug	butamben	CACNA1E MGAM KCND3	7.00e-05	15	125	3	CID000002482
Drug	2,2',3,5,5'-pentachlorobiphenyl	UGT1A10 UGT1A8 UGT1A9	7.00e-05	15	125	3	CID000040469
Drug	afloqualone	UGT1A10 UGT1A8 UGT1A9	7.00e-05	15	125	3	CID000002040
Drug	naphthyl sulphate	UGT1A10 UGT1A8 UGT1A9	7.00e-05	15	125	3	CID000114775
Drug	coumarin-3-carboxylic acid	UGT1A10 UGT1A8 UGT1A9	7.00e-05	15	125	3	CID000010752
Drug	bergamottin	UGT1A10 UGT1A8 UGT1A9	7.00e-05	15	125	3	ctd:C068337
Drug	sulforaphane nitrile	UGT1A10 UGT1A8 UGT1A9	7.00e-05	15	125	3	CID000543743
Drug	AC1N8H7N	UGT1A10 UGT1A8 UGT1A9 KCNJ3 SLC45A2	7.05e-05	78	125	5	CID004318740
Drug	testosterone glucuronide	UGT1A10 UGT1A8 UGT1A9 SLC45A2	7.49e-05	41	125	4	CID000108192
Drug	1'-hydroxyestragole	UGT1A10 UGT1A8 UGT1A9	8.59e-05	16	125	3	CID000040003
Drug	bilirubin-phosphate	UGT1A10 UGT1A8 UGT1A9	8.59e-05	16	125	3	CID005497144
Drug	sodium cholate	CACNA1E UGT1A10 UGT1A8 UGT1A9 LRP1B RXRA ACOX3 SLCO1A2 CLTA SLC27A4	8.70e-05	408	125	10	CID000000303
Drug	His-r	LYST HARS1	8.94e-05	3	125	2	CID000126923
Drug	calcium carbonate phosphate	MGAM OPN1SW	8.94e-05	3	125	2	CID006337635
Drug	Woodward's reagent K	UGT1A10 UGT1A8 UGT1A9 SLC4A3	9.05e-05	43	125	4	CID000077804
Drug	N-hydroxy-PhIP	UGT1A10 UGT1A8 UGT1A9 SLC45A2	9.05e-05	43	125	4	CID000104954
Drug	rottlerin; Down 200; 10uM; MCF7; HT_HG-U133A_EA	CUL2 UBE4B DYNC2H1 FPGT ACOX3 UBE2B KCNJ3	9.07e-05	191	125	7	941_DN
Drug	2-propylpentanoic acid; Up 200; 500uM; MCF7; HT_HG-U133A	FMO5 DYNC2H1 ATP10B UBE2B SH3TC1 SASH3 SLCO1A2	9.68e-05	193	125	7	5600_UP
Drug	Decamethonium bromide [541-22-0]; Up 200; 9.6uM; HL60; HT_HG-U133A	PDK3 SH3TC1 KCNJ3 SLCO1A2 RECQL5 SLC17A7 PADI1	9.68e-05	193	125	7	2933_UP
Drug	anthraflavic acid	UGT1A10 UGT1A8 UGT1A9 SLC45A2	9.92e-05	44	125	4	CID000006776
Disease	X-21339 measurement	UGT1A10 UGT1A8 UGT1A9 SLCO1A2	9.64e-09	7	122	4	EFO_0800808
Disease	indole-3-carboxylate measurement	UGT1A10 UGT1A8 UGT1A9	6.90e-08	3	122	3	EFO_0800043
Disease	blood 4-oxo-retinoic acid measurement	UGT1A10 UGT1A8 UGT1A9	6.90e-08	3	122	3	EFO_0022216
Disease	N-acetyl-4-chlorophenylalanine measurement	UGT1A10 UGT1A8 UGT1A9	6.85e-07	5	122	3	EFO_0801060
Disease	5-hydroxyindole sulfate measurement	UGT1A10 UGT1A8 UGT1A9	6.85e-07	5	122	3	EFO_0800085
Disease	nuclear receptor subfamily 1 group D member 2 measurement	UGT1A10 UGT1A8 UGT1A9	6.85e-07	5	122	3	EFO_0801853
Disease	3-carboxy-4-methyl-5-pentyl-2-furanpropionate (3-CMPFP) measurement	UGT1A10 UGT1A8 UGT1A9	1.37e-06	6	122	3	EFO_0800566
Disease	X-11793--oxidized bilirubin measurement	UGT1A10 UGT1A8 UGT1A9	3.80e-06	8	122	3	EFO_0021260
Disease	Succinimide measurement	UGT1A10 UGT1A8 UGT1A9	3.80e-06	8	122	3	EFO_0022118
Disease	X-11530 measurement	UGT1A10 UGT1A8 UGT1A9	3.80e-06	8	122	3	EFO_0021249
Disease	sulfate of piperine metabolite C16H19NO3 (2) measurement	UGT1A10 UGT1A8 UGT1A9	3.80e-06	8	122	3	EFO_0801034
Disease	cholelithiasis, bilirubin measurement	UGT1A10 UGT1A8 UGT1A9	3.80e-06	8	122	3	EFO_0004570, EFO_0004799
Disease	X-11522 measurement	UGT1A10 UGT1A8 UGT1A9	3.80e-06	8	122	3	EFO_0800696
Disease	X-10458 measurement	UGT1A10 UGT1A8 UGT1A9	3.80e-06	8	122	3	EFO_0800692
Disease	X-24849 measurement	UGT1A10 UGT1A8 UGT1A9	3.80e-06	8	122	3	EFO_0800909
Disease	serum N-desmethylclozapine measurement	UGT1A10 UGT1A8 UGT1A9	3.80e-06	8	122	3	EFO_0600043
Disease	plasma clozapine measurement	UGT1A10 UGT1A8 UGT1A9	3.80e-06	8	122	3	EFO_0600038
Disease	membrane-associated progesterone receptor component 1 measurement	UGT1A10 UGT1A8 UGT1A9	3.80e-06	8	122	3	EFO_0802740
Disease	X-16946 measurement	UGT1A10 UGT1A8 UGT1A9	3.80e-06	8	122	3	EFO_0800766
Disease	X-11442 measurement	UGT1A10 UGT1A8 UGT1A9	5.69e-06	9	122	3	EFO_0021236
Disease	X-11441 measurement	UGT1A10 UGT1A8 UGT1A9	5.69e-06	9	122	3	EFO_0021235
Disease	circulating cell free DNA measurement	UGT1A10 UGT1A8 UGT1A9	5.69e-06	9	122	3	EFO_0004739
Disease	sulfate of piperine metabolite C18H21NO3 (3) measurement	UGT1A10 UGT1A8 UGT1A9	5.69e-06	9	122	3	EFO_0801037
Disease	sulfate of piperine metabolite C18H21NO3 (1) measurement	UGT1A10 UGT1A8 UGT1A9	5.69e-06	9	122	3	EFO_0801036
Disease	X-11880 measurement	UGT1A10 UGT1A8 UGT1A9	5.69e-06	9	122	3	EFO_0800698
Disease	protein-tyrosine kinase 6 measurement	UGT1A10 UGT1A8 UGT1A9	5.69e-06	9	122	3	EFO_0020691
Disease	testis-specific chromodomain protein Y 1 measurement	UGT1A10 UGT1A8 UGT1A9	5.69e-06	9	122	3	EFO_0802127
Disease	bilirubin measurement, response to xenobiotic stimulus	UGT1A10 UGT1A8 UGT1A9	5.69e-06	9	122	3	EFO_0004570, GO_0009410
Disease	bilirubin measurement, response to tenofovir	UGT1A10 UGT1A8 UGT1A9	8.10e-06	10	122	3	EFO_0004570, EFO_0009279
Disease	indoleacetate measurement	UGT1A10 UGT1A8 UGT1A9	8.10e-06	10	122	3	EFO_0021015
Disease	X-21448 measurement	UGT1A10 UGT1A8 UGT1A9	8.10e-06	10	122	3	EFO_0800816
Disease	UDP-glucuronosyltransferase 1-6 measurement	UGT1A10 UGT1A8 UGT1A9	8.10e-06	10	122	3	EFO_0802185
Disease	X-23974 measurement	UGT1A10 UGT1A8 UGT1A9	8.10e-06	10	122	3	EFO_0800867
Disease	pregnenetriol sulfate measurement	UGT1A10 UGT1A8 UGT1A9	1.11e-05	11	122	3	EFO_0800586
Disease	plasma N-desmethylclozapine measurement	UGT1A10 UGT1A8 UGT1A9	1.11e-05	11	122	3	EFO_0600039
Disease	histidine betaine (hercynine) measurement	UGT1A10 UGT1A8 UGT1A9	1.11e-05	11	122	3	EFO_0800972
Disease	X-21796 measurement	UGT1A10 UGT1A8 UGT1A9	1.11e-05	11	122	3	EFO_0800825
Disease	insomnia, bilirubin measurement	UGT1A10 UGT1A8 UGT1A9	1.11e-05	11	122	3	EFO_0004570, EFO_0004698
Disease	aldosterone measurement	UGT1A10 UGT1A8 UGT1A9	1.11e-05	11	122	3	EFO_0010219
Disease	p-cresol glucuronide measurement	UGT1A10 UGT1A8 UGT1A9	1.48e-05	12	122	3	EFO_0800079
Disease	biliverdin measurement	UGT1A10 UGT1A8 UGT1A9	1.48e-05	12	122	3	EFO_0021033
Disease	vitamin D deficiency	UGT1A10 UGT1A8 UGT1A9 PADI1	1.65e-05	37	122	4	EFO_0003762
Disease	cognitive function measurement, self reported educational attainment	CACNA1E ARHGAP15 SGCG PFKFB4 SYT7 KCNJ3 MTMR2 PKHD1 HARS1	1.77e-05	355	122	9	EFO_0004784, EFO_0008354
Disease	pregnenetriol disulfate measurement	UGT1A10 UGT1A8 UGT1A9	1.91e-05	13	122	3	EFO_0800587
Disease	X-24588 measurement	UGT1A10 UGT1A8 UGT1A9	1.91e-05	13	122	3	EFO_0800898
Disease	retinol dehydrogenase 16 measurement	UGT1A10 UGT1A8 UGT1A9	1.91e-05	13	122	3	EFO_0802007
Disease	hormone measurement	UGT1A10 UGT1A8 UGT1A9 NAALADL2 RIN2	2.65e-05	84	122	5	EFO_0004730
Disease	low density lipoprotein cholesterol measurement, body fat percentage	UGT1A10 UGT1A8 UGT1A9	4.49e-05	17	122	3	EFO_0004611, EFO_0007800
Disease	X-21441 measurement	UGT1A10 UGT1A8 UGT1A9	4.49e-05	17	122	3	EFO_0800814
Disease	angiopoietin-related protein 1 measurement	UGT1A10 UGT1A8 UGT1A9	5.38e-05	18	122	3	EFO_0801382
Disease	tissue factor measurement	UGT1A10 UGT1A8 UGT1A9	8.69e-05	21	122	3	EFO_0010623
Disease	Nystagmus	ATP10B NAALADL2 SH3TC1	8.69e-05	21	122	3	HP_0000639
Disease	cognitive function measurement	CNTN4 CACNA1E ARHGAP15 DSP SGCG CNOT10 FPGT KMT2E NAALADL2 LRP1B SYT7 RXRA KCNJ3 MTMR2 PKHD1 HARS1 MYBPC2	8.73e-05	1434	122	17	EFO_0008354
Disease	Chediak-Higashi syndrome (implicated_via_orthology)	LYST NSMAF	1.01e-04	4	122	2	DOID:2935 (implicated_via_orthology)
Disease	serum gamma-glutamyl transferase measurement	UGT1A10 UGT1A8 UGT1A9 CDC42BPB NBEAL2 HPRT1 SLCO1A2 SVIL PKHD1 GOLGA4 NSMAF ARAP2 DNMT1	1.09e-04	914	122	13	EFO_0004532
Disease	congenital heart disease (implicated_via_orthology)	RXRA KMT2C UBE2B MYBPC2	1.95e-04	69	122	4	DOID:1682 (implicated_via_orthology)
Disease	neuroblastoma, cutaneous melanoma	UGT1A10 UGT1A8 UGT1A9	2.09e-04	28	122	3	EFO_0000389, EFO_0000621
Disease	xanthurenate measurement	UGT1A10 UGT1A8 UGT1A9	2.33e-04	29	122	3	EFO_0010551
Disease	response to dolutegravir	UGT1A10 UGT1A8 UGT1A9	2.58e-04	30	122	3	EFO_0600017
Disease	lysophosphatidylcholine 20:4 measurement	SGCG SYT7 KCND3	3.13e-04	32	122	3	EFO_0010363
Disease	small cell lung carcinoma	DYNC2H1 ADGRV1 NRP1 DLEC1	3.45e-04	80	122	4	EFO_0000702
Disease	Sudden Cardiac Arrest	DSP KCND3	4.67e-04	8	122	2	C1720824
Disease	vitamin D measurement	TDRD15 UGT1A10 UGT1A8 UGT1A9 KMT2E PDILT PADI1	5.10e-04	336	122	7	EFO_0004631
Disease	childhood aggressive behaviour measurement	CNTN4 DLEC1 PLCG2 HECTD1	5.18e-04	89	122	4	EFO_0007663
Disease	neuroticism measurement, cognitive function measurement	CACNA1E ARHGAP15 NBEAL1 FPGT SQOR LRP1B NRP1 MTMR2 MYBPC2	5.91e-04	566	122	9	EFO_0007660, EFO_0008354
Disease	thoracic aortic calcification measurement	COL6A6 VPS13A	5.99e-04	9	122	2	EFO_0010273
Disease	Colorectal Carcinoma	CNTN4 SELENOP KMT2C SH3TC1 KCND3 SLCO1A2 PDILT PANK4 VPS13A PKHD1	6.88e-04	702	122	10	C0009402
Disease	upper face morphology measurement	ADGRV1 NRP1 RIN2 DLEC1	7.16e-04	97	122	4	EFO_0010949
Disease	Tetralogy of Fallot	NRP1 MFSD1	7.47e-04	10	122	2	HP_0001636
Disease	gallstones	AP1S3 UGT1A10 UGT1A8 UGT1A9	1.07e-03	108	122	4	EFO_0004210
Disease	dodecanedioate measurement	UGT1A10 UGT1A8	1.09e-03	12	122	2	EFO_0021054
Disease	unipolar depression, multiple sclerosis	TDRD15 PADI1	1.09e-03	12	122	2	EFO_0003761, MONDO_0005301
Disease	vitamin D measurement, COVID-19	UGT1A10 UGT1A8 UGT1A9	1.11e-03	49	122	3	EFO_0004631, MONDO_0100096
Disease	health study participation	ARHGAP15 FPGT PFKFB4 SQOR LRP1B	1.33e-03	195	122	5	EFO_0010130
Disease	late-onset Alzheimers disease	SELENOP UGT1A10 UGT1A8 NAALADL2 DLEC1 PLCG2	1.38e-03	292	122	6	EFO_1001870
Disease	1-methylurate measurement	CNTN4 SLC18A1	1.49e-03	14	122	2	EFO_0021173
Disease	lysophosphatidylcholine 15:0 measurement	LRP1B PKHD1	1.49e-03	14	122	2	EFO_0020941
Disease	amyotrophic lateral sclerosis, age at onset	SLC18A1 ARAP2	1.72e-03	15	122	2	EFO_0004847, MONDO_0004976
Disease	employment status	ARHGAP15 SQOR	1.72e-03	15	122	2	EFO_0005241
Disease	urate measurement, spine bone mineral density	UGT1A10 UGT1A8 UGT1A9	1.80e-03	58	122	3	EFO_0004531, EFO_0007701
Disease	level of Phosphatidylcholine (18:0_20:3) in blood serum	TLCD4 NOMO1	1.96e-03	16	122	2	OBA_2045093
Disease	lysophosphatidylcholine measurement	MGAM SYT7 PLA2G4B	2.18e-03	62	122	3	EFO_0010224
Disease	hypertrophic cardiomyopathy (is_marker_for)	DSP DNMT1	2.21e-03	17	122	2	DOID:11984 (is_marker_for)
Disease	coronary artery disease, plasminogen activator inhibitor 1 measurement	TDRD15 NBEAL1 DYNC2H1	2.29e-03	63	122	3	EFO_0001645, EFO_0004792
Disease	keratoconus	LRP1B RXRA PKHD1	2.61e-03	66	122	3	MONDO_0015486
Disease	lung non-small cell carcinoma (is_implicated_in)	LRP1B NRP1 KMT2C DNMT1	2.70e-03	139	122	4	DOID:3908 (is_implicated_in)
Disease	carotid artery intima media thickness	TDRD15 DYNC2H1 RBBP8 LRP1B SVIL MARF1 DLEC1	2.73e-03	450	122	7	EFO_0007117
Disease	opioid dependence	ADGRV1 TXK DLEC1 PLCG2 C9	3.10e-03	237	122	5	EFO_0005611
Disease	tissue plasminogen activator measurement, coronary artery disease	TDRD15 NBEAL1 DYNC2H1	3.21e-03	71	122	3	EFO_0001645, EFO_0004791
Disease	type 2 diabetes mellitus (biomarker_via_orthology)	UGT1A10 UGT1A8 UGT1A9 DNMT1	3.30e-03	147	122	4	DOID:9352 (biomarker_via_orthology)
Disease	bipolar disorder, body mass index	NAALADL2 RIN2 PKHD1	3.34e-03	72	122	3	EFO_0004340, MONDO_0004985
Disease	myocardial infarction	TDRD15 ARHGAP15 NBEAL1 DYNC2H1 PLCG2 TNS1	3.41e-03	350	122	6	EFO_0000612
Disease	Alzheimer disease, educational attainment	ARHGAP15 PFKFB4 LRP1B KCNJ3 MTMR2	3.70e-03	247	122	5	EFO_0011015, MONDO_0004975
Disease	response to alcohol	AP1S3 NAALADL2 PKHD1	3.75e-03	75	122	3	EFO_0005526
Disease	JT interval	SLC4A3 NDUFAF1 KCNA7 KCND3 BRWD1	3.76e-03	248	122	5	EFO_0007885
Disease	chronic widespread pain	SNX13 PLCG2	4.05e-03	23	122	2	EFO_0010099
Disease	Paroxysmal atrial fibrillation	UBE4B OPN1SW GTF2I KCND3	4.07e-03	156	122	4	C0235480
Disease	familial atrial fibrillation	UBE4B OPN1SW GTF2I KCND3	4.07e-03	156	122	4	C3468561
Disease	Persistent atrial fibrillation	UBE4B OPN1SW GTF2I KCND3	4.07e-03	156	122	4	C2585653

Protein segments in the cluster

Peptide	Gene	Start	Entry
YDNVEKLFPGFEIET	ASNS	216	P08243
GFSGPLLVFEEAFFK	SLC4A3	766	P48751
YFIGFLGDELIFLDP	ATG4A	266	Q8WYN0
FVEPYFKGDERETSL	RBBP8	776	Q99708
KTEPYFIGIFCFEAG	CACNA1E	126	Q15878
IELFFSGSAKPIYDD	DNMT1	431	P26358
VDFLDAYPGILDQKF	ACOX3	486	O15254
KFVIDVGYERFLGPE	ACTR3B	266	Q9P1U1
AEGIIEFDPKYTAFE	ADGRV1	4396	Q8WXG9
LYQDGVFKFTVYIPD	AKTIP	116	Q9H8T0
SLPFDEDYIIEIKPF	CNTN4	961	Q8IWV2
FEIYLPSERVFLFGA	ARAP2	971	Q8WZ64
LKYDPDVVVTDFRFG	AADACL3	81	Q5VUY0
FFDPLFVEQKYELGA	CLDN10	146	P78369
FIPYLAYKGSDIDVF	ATP10B	1211	O94823
DIFEGVYFPAISLYK	ASH2L	556	Q9UBL3
VKELIPEFFYFPEFL	NBEAL1	2151	Q6ZS30
FAFFKVLPGDYEILA	NOMO3	171	P69849
EIKFYVEGLTFPDAD	PADI1	246	Q9ULC6
LEKELLFFAYDVFGI	P3H1	371	Q32P28
FVIFPTDLEIYKAFS	PARP9	466	Q8IXQ6
NFEKAYFILDEFIIG	AP1S3	106	Q96PC3
LAEFFEDLADKPYTF	FXN	106	Q16595
IFFTLDSVKLPDGYV	CT55	196	Q8WUE5
FAFFKVLPGDYEILA	NOMO2	171	Q5JPE7
YPDTLLGSTEKEFFF	KCND3	61	Q9UK17
EETFPAYLQEAFFGK	KMT2C	1356	Q8NEZ4
IAVDPIAGKLFFTDY	LRP1B	331	Q9NZR2
VSLFGEPTEFEYLRK	GOLGA4	2166	Q13439
VFYEAFGNPEEFVIV	IBTK	1321	Q9P2D0
FVYGKCPFIDDFILA	CAMKK1	346	Q8N5S9
LDHKTLYFDVEPFVF	KAT8	271	Q9H7Z6
AFTRGVEDDVFIKYP	MGAM	2226	O43451
FVYKEFSRFHEEILP	PDE6B	781	P35913
YKSFEFFLPDNEEGL	PFKFB4	86	Q16877
SFPGIYDALFDIESK	FOLH1B	396	Q9HBA9
IFDNGLYDEKPLTFF	NRDE2	666	Q9H7Z3
FAFFKVLPGDYEILA	NOMO1	171	Q15155
PVFVFPTELIFYADD	MOSPD1	16	Q9UJG1
IPKGTEITIAFDFDY	KMT2E	436	Q8IZD2
PLFAFEYKEVFPENG	MTMR2	191	Q13614
FPFIGLGKVFFTEKF	MFSD1	281	Q9H3U5
IPEDFFIFYGDLVYL	LRRC38	71	Q5VT99
KYGAFIPSELFGSEF	PLA2G4B	466	P0C869
AEPFLFVDEFLTYLF	PLCG2	281	P16885
GLKLPDFQDSIFEYF	CDC42BPB	941	Q9Y5S2
IYGNEFDKRFFVPAE	IL20RA	291	Q9UHF4
FPDEDSYQKFIPFIG	PACS1	736	Q6VY07
FEIPDKFVVGYALDY	HPRT1	181	P00492
PLVSLFFYVVTDGKE	MOGS	201	Q13724
FFYVVTDGKEVLLPE	MOGS	206	Q13724
AVLESDPYFGFEEAK	PANK4	576	Q9NVE7
GPFLFIKFVSDYETH	NRP1	116	O14786
YGFTFHKPDDVFKEI	DNAJB7	86	Q7Z6W7
FPRFYFIGDDDLLEI	DYNC2H1	1426	Q8NCM8
LGPTLEFYALVAAEF	HECTD1	2171	Q9ULT8
DFVAILPYFVALGTE	KCNA7	246	Q96RP8
LEFLVGLFKPFVESY	GNPAT	566	O15228
EFPLIFDRPSYVFDV	CDHR3	456	Q6ZTQ4
GYSFDFPFLEDSVKV	FMO5	331	P49326
IYAAEKAITGFDDPF	DSP	2086	P15924
LADKVDGPFFLEIDF	NDUFAF1	286	Q9Y375
IFESPFLTETGEYYK	CUL2	206	Q13617
YFLGFEAPEKIAELE	BRWD1	351	Q9NSI6
KELIPEFFYLPEFLV	LYST	3291	Q99698
YGFTKLLELFEAIPD	MARF1	1301	Q9Y4F3
PFNLFYIEKDTGDIF	DSC1	181	Q08554
FPRFYFVGDEDLLEI	DYNC1H1	1626	Q14204
DDLYGPIAFKDFILS	FAM47A	731	Q5JRC9
LDGATDFKELIPEFY	NSMAF	436	Q92636
DFKELIPEFYGDDVS	NSMAF	441	Q92636
LFESFPEDFYVEGLP	GTF2I	761	P78347
VFLAKPPIGFFTDYE	DLEC1	371	Q9Y238
VGSFKFIYVDVLPEE	SASH3	221	O75995
ADFIDGPIKAYLFDV	SLC45A2	156	Q9UMX9
LFFFKLIGDTPIDTF	RXRA	436	P19793
FEYLTLFGIDDKISF	HARS1	306	P12081
DPEVLFYLDDFGTKL	COL6A6	856	A6NMZ7
DLADLPYIEFGKGFE	COL6A6	1341	A6NMZ7
LPTTYEKGEYFAFLE	C9	326	P02748
YSIGEFEFIRFDKPG	FPGT	186	O14772
EEEFYLFKNISSVGP	OPN1SW	6	P03999
TPFDFELYLVGDGKY	GRIN3B	491	O60391
FYDVIKDFPELTFGV	PDILT	191	Q8N807
NETFLFEGFPYEKVV	SYT7	201	O43581
VFLEGFLETLFPQYK	SNX13	921	Q9Y5W8
AEFDYKAEPLETFPF	SQOR	391	Q9Y6N5
PKEVLVFDFGSEVYV	SVIL	1591	O95425
KILPGNSFEVEFIDY	TDRD15	1366	B5MCY1
ELFKEAPFSEFFLDP	YARS2	391	Q9Y2Z4
FLDSKGLEYPAVVEF	UPF3A	136	Q9H1J1
DVKELIPEFFYFPDF	NBEAL2	2211	Q6ZNJ1
LFPYSFFEQFVEAIK	ARHGAP15	366	Q53QZ3
VLGDIIFYDLKDPFD	SH3TC1	1241	Q8TE82
PAYFEEVFGFEISKV	SLC17A7	326	Q9P2U7
VLVDTDLPFFKGLYV	PKHD1	2771	P08F94
LPLGISYIEDFAKFE	SLCO1A2	176	P46721
IEYKEKFGFDPFIST	PDK3	131	Q15120
FSFLTFPYVEEAIKI	SELENOP	151	P49908
EGESEFLFPLYAKEI	SGCG	81	Q13326
EAFYKQPFADVIGYV	CLTA	166	P09496
SVGEKLYQFIEPFEE	CNOT10	131	Q9H9A5
FYDVQFKELISDPYG	RECQL5	226	O94762
FELYPEFLLVFKEAF	TMEM31	91	Q5JXX7
CFDIFFYDPGVTLVK	VNN2	211	O95498
FKVGDPEEYSLFLFV	RIN2	826	Q8WYP3
VFDGLPLYDDVKVQF	TPTE	466	P56180
IYPSDFAVEILFGEK	TPTE	526	P56180
PADVVLFEGILVFYS	UCK1	131	Q9HA47
YSFDEFTKEPFIVHG	VPS13A	3111	Q96RL7
YLKESSFDAVFLDPF	UGT1A10	136	Q9HAW8
FDPAIVKDPLFYLDA	SLC27A4	606	Q6P1M0
PEFYVEDVAEFLFFI	UBE4B	881	O95155
DDRFPEYGKVEFVFS	TNS1	291	Q9HBL0
GLYIFLFDEATKADP	TLCD4	66	Q96MV1
KSYFLFIFGVEFVGP	PROKR2	221	Q8NFJ6
FPDGFYKGKLFVFDE	TSTD2	391	Q5T7W7
VYPADVVLFEGILAF	UCK2	126	Q9BZX2
YLKESSFDAVFLDPF	UGT1A9	136	O60656
EPEFYTSLFQEVGLK	RALGAPB	1476	Q86X10
LDDEYVSSFGAKFPI	TXK	416	P42681
KYDPSYIEFGFVAVI	ZBED9	736	Q6R2W3
SFFIPDIEYLSDIKG	ZNF622	276	Q969S3
PYREIFEFFIEDFKT	TSNAXIP1	76	Q2TAA8
GTFKLVIEFSEEYPN	UBE2B	51	P63146
YLKESSFDAVFLDPF	UGT1A8	136	Q9HAW9
YEFVGKSAPFLILAF	SLC18A1	251	P54219
RFFPVISLEEGFFKV	KCNJ3	326	P48549
FAYEDIKTLEGPSFL	NAALADL2	591	Q58DX5
GITFKPFEYKEHDFR	MYBPC2	1031	Q14324