Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	RNA polymerase II cis-regulatory region sequence-specific DNA binding	HOXA11 SP8 ZFHX3 EVX1 OTX1 SOX30 BHLHE22 ZIC2 TBX2 PITX3 FOXB2	3.96e-06	1244	34	11	GO:0000978
GeneOntologyMolecularFunction	cis-regulatory region sequence-specific DNA binding	HOXA11 SP8 ZFHX3 EVX1 OTX1 SOX30 BHLHE22 ZIC2 TBX2 PITX3 FOXB2	4.88e-06	1271	34	11	GO:0000987
GeneOntologyMolecularFunction	DNA-binding transcription factor activity, RNA polymerase II-specific	HOXA11 SP8 ZFHX3 EVX1 OTX1 SOX30 BHLHE22 ZIC2 TBX2 PITX3 FOXB2	1.33e-05	1412	34	11	GO:0000981
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	HOXA11 SP8 ZFHX3 EVX1 OTX1 SOX30 BHLHE22 ZIC2 TBX2 PITX3 FOXB2	1.81e-05	1459	34	11	GO:0000977
GeneOntologyMolecularFunction	chromatin binding	KDM3B RCOR1 TNRC18 TRIM28 BHLHE22 ZIC2	1.40e-03	739	34	6	GO:0003682
GeneOntologyBiologicalProcess	positive regulation of transcription by RNA polymerase II	ZFHX3 EVX1 AKIRIN2 OTX1 CDK13 SOX30 BHLHE22 ZIC2 TBX2 PITX3	4.13e-05	1390	33	10	GO:0045944
GeneOntologyBiologicalProcess	negative regulation of DNA-templated transcription	ZFHX3 AKIRIN2 RCOR1 TRIM28 PRDM6 SOX30 BHLHE22 ZIC2 ZNF503 TBX2	4.36e-05	1399	33	10	GO:0045892
GeneOntologyBiologicalProcess	negative regulation of RNA biosynthetic process	ZFHX3 AKIRIN2 RCOR1 TRIM28 PRDM6 SOX30 BHLHE22 ZIC2 ZNF503 TBX2	4.75e-05	1413	33	10	GO:1902679
GeneOntologyBiologicalProcess	regionalization	HOXA11 SP8 OTX1 BHLHE22 ZIC2 TBX2	9.77e-05	478	33	6	GO:0003002
GeneOntologyBiologicalProcess	stem cell differentiation	FBXL17 ZFP36L2 CDK13 ZIC2 TBX2	1.17e-04	306	33	5	GO:0048863
GeneOntologyBiologicalProcess	pattern specification process	HOXA11 SP8 OTX1 BHLHE22 ZIC2 TBX2	1.65e-04	526	33	6	GO:0007389
GeneOntologyBiologicalProcess	regulation of cell development	HOXA11 RCOR1 SH3RF1 ZFP36L2 MARCKS LRP8 SHB PITX3	2.60e-04	1095	33	8	GO:0060284
GeneOntologyBiologicalProcess	embryo development	HOXA11 SP8 EVX1 AKIRIN2 OTX1 TRIM28 MARCKS ZIC2 TBX2	3.15e-04	1437	33	9	GO:0009790
GeneOntologyCellularComponent	chromatin	KDM3B SP8 ZFHX3 EVX1 AKIRIN2 OTX1 TRIM28 SOX30 BHLHE22 TBX2 PITX3 FOXB2	1.92e-06	1480	34	12	GO:0000785
GeneOntologyCellularComponent	transcription regulator complex	HOXA11 ZFHX3 AKIRIN2 RCOR1 TRIM28 TBX2	3.57e-04	596	34	6	GO:0005667
Domain	-	HOXA11 ZFHX3 EVX1 RCOR1 OTX1 PITX3	9.01e-06	283	33	6	1.10.10.60
Domain	Homeobox_CS	HOXA11 ZFHX3 EVX1 OTX1 PITX3	1.76e-05	186	33	5	IPR017970
Domain	Homeodomain-like	HOXA11 ZFHX3 EVX1 RCOR1 OTX1 PITX3	2.23e-05	332	33	6	IPR009057
Domain	Homeobox	HOXA11 ZFHX3 EVX1 OTX1 PITX3	5.27e-05	234	33	5	PF00046
Domain	HOMEOBOX_1	HOXA11 ZFHX3 EVX1 OTX1 PITX3	5.49e-05	236	33	5	PS00027
Domain	HOX	HOXA11 ZFHX3 EVX1 OTX1 PITX3	5.60e-05	237	33	5	SM00389
Domain	Homeobox_dom	HOXA11 ZFHX3 EVX1 OTX1 PITX3	5.83e-05	239	33	5	IPR001356
Domain	HOMEOBOX_2	HOXA11 ZFHX3 EVX1 OTX1 PITX3	5.83e-05	239	33	5	PS50071
Domain	Zinc_finger_PHD-type_CS	DIDO1 TRIM28	5.87e-03	65	33	2	IPR019786
Domain	-	SP8 ZFHX3 PRDM6 ZIC2 ZNF503	6.38e-03	679	33	5	3.30.160.60
Domain	Znf_C2H2/integrase_DNA-bd	SP8 ZFHX3 PRDM6 ZIC2 ZNF503	6.99e-03	694	33	5	IPR013087
Domain	PHD	DIDO1 TRIM28	7.75e-03	75	33	2	PF00628
Domain	Znf_PHD-finger	DIDO1 TRIM28	8.57e-03	79	33	2	IPR019787
Domain	PHD	DIDO1 TRIM28	1.08e-02	89	33	2	SM00249
Domain	ZINC_FINGER_C2H2_2	SP8 ZFHX3 PRDM6 ZIC2 ZNF503	1.10e-02	775	33	5	PS50157
Domain	Homeobox_metazoa	HOXA11 EVX1	1.10e-02	90	33	2	IPR020479
Domain	ZINC_FINGER_C2H2_1	SP8 ZFHX3 PRDM6 ZIC2 ZNF503	1.11e-02	777	33	5	PS00028
Domain	Znf_PHD	DIDO1 TRIM28	1.12e-02	91	33	2	IPR001965
Domain	ZF_PHD_2	DIDO1 TRIM28	1.22e-02	95	33	2	PS50016
Domain	Znf_C2H2-like	SP8 ZFHX3 PRDM6 ZIC2 ZNF503	1.22e-02	796	33	5	IPR015880
Domain	ZF_PHD_1	DIDO1 TRIM28	1.24e-02	96	33	2	PS01359
Pubmed	A census of human transcription factors: function, expression and evolution.	HOXA11 ZFHX3 EVX1 RCOR1 OTX1 ZFP36L2 SOX30 BHLHE22 ZIC2 TBX2 PITX3	5.98e-10	908	34	11	19274049
Pubmed	Impact of cytosine methylation on DNA binding specificities of human transcription factors.	HOXA11 SP8 EVX1 OTX1 SOX30 BHLHE22 TBX2 PITX3	4.32e-08	544	34	8	28473536
Pubmed	Dlx1&2 and Mash1 transcription factors control MGE and CGE patterning and differentiation through parallel and overlapping pathways.	SP8 ZFHX3 OTX1 ZNF503 SHB	1.72e-07	130	34	5	19386638
Pubmed	Dlx1&2 and Mash1 transcription factors control striatal patterning and differentiation through parallel and overlapping pathways.	SP8 ZFHX3 OTX1 ZNF503 SHB	2.00e-07	134	34	5	19030180
Pubmed	Interaction network of human early embryonic transcription factors.	ZFHX3 RCOR1 TNRC18 PRDM6 ZNF503 TBX2	1.07e-06	351	34	6	38297188
Pubmed	The Tumor Suppressor CIC Directly Regulates MAPK Pathway Genes via Histone Deacetylation.	HOXA11 ZFHX3 RCOR1 OTX1 TRIM28 ZIC2 TBX2	1.30e-06	583	34	7	29844126
Pubmed	Sp8 controls the anteroposterior patterning at the midbrain-hindbrain border.	SP8 OTX1 PITX3	1.93e-06	25	34	3	16571633
Pubmed	A vertebrate gene related to orthodenticle contains a homeodomain of the bicoid class and demarcates anterior neuroectoderm in the gastrulating mouse embryo.	EVX1 OTX1	5.56e-06	4	34	2	8101484
Pubmed	A High-Density Map for Navigating the Human Polycomb Complexome.	FBXL17 DIDO1 RCOR1 CKAP4 TRIM28 ZNF503	7.73e-06	495	34	6	27705803
Pubmed	A screen for downstream effectors of Neurogenin2 in the embryonic neocortex.	ZFP36L2 MARCKS BHLHE22	1.83e-05	52	34	3	15328020
Pubmed	Two Pairs of ON and OFF Retinal Ganglion Cells Are Defined by Intersectional Patterns of Transcription Factor Expression.	EVX1 BHLHE22 PITX3	1.93e-05	53	34	3	27210758
Pubmed	Single-cell transcriptomics of the early developing mouse cerebral cortex disentangle the spatial and temporal components of neuronal fate acquisition.	SP8 BHLHE22 ZNF503	2.28e-05	56	34	3	34170322
Pubmed	Homologs of genes expressed in Caenorhabditis elegans GABAergic neurons are also found in the developing mouse forebrain.	RCOR1 PITX3 FOXB2	2.41e-05	57	34	3	21122108
Pubmed	Dual-mode operation of neuronal networks involved in left-right alternation.	EVX1 BHLHE22	2.59e-05	8	34	2	23812590
Pubmed	Transcriptional heterogeneity of ventricular zone cells in the ganglionic eminences of the mouse forebrain.	SP8 ZFHX3 ZNF503	2.81e-05	60	34	3	35175194
Pubmed	Location and size of dopaminergic and serotonergic cell populations are controlled by the position of the midbrain-hindbrain organizer.	OTX1 PITX3	3.33e-05	9	34	2	12764108
Pubmed	Genetic chimeras reveal the autonomy requirements for Vsx2 in embryonic retinal progenitor cells.	OTX1 BHLHE22	3.33e-05	9	34	2	25927996
Pubmed	The AERO system: a 3D-like approach for recording gene expression patterns in the whole mouse embryo.	HOXA11 SP8 TBX2 PITX3	3.59e-05	191	34	4	24146773
Pubmed	Foxa2 acts as a co-activator potentiating expression of the Nurr1-induced DA phenotype via epigenetic regulation.	RCOR1 PITX3	4.15e-05	10	34	2	24496614
Pubmed	Graded Arrays of Spinal and Supraspinal V2a Interneuron Subtypes Underlie Forelimb and Hindlimb Motor Control.	SP8 ZFHX3	4.15e-05	10	34	2	29398364
Pubmed	A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.	HOXA11 DIDO1 ZFHX3 OTX1 SH3RF1 TRIM28	5.81e-05	709	34	6	22988430
Pubmed	Orientation of the Hoxa complex and placement of the Hd locus distal to Hoxa2 on mouse chromosome 6.	HOXA11 EVX1	6.08e-05	12	34	2	8833244
Pubmed	Forebrain and midbrain regions are deleted in Otx2-/- mutants due to a defective anterior neuroectoderm specification during gastrulation.	EVX1 OTX1	6.08e-05	12	34	2	7588062
Pubmed	TRIM33 drives prostate tumor growth by stabilizing androgen receptor from Skp2-mediated degradation.	KDM3B DIDO1 ZFHX3 TRIM28	6.23e-05	220	34	4	35785414
Pubmed	Two Notch ligands, Dll1 and Jag1, are differently restricted in their range of action to control neurogenesis in the mammalian spinal cord.	EVX1 BHLHE22	7.19e-05	13	34	2	21124801
Pubmed	Sox6 and Otx2 control the specification of substantia nigra and ventral tegmental area dopamine neurons.	ZNF503 PITX3	7.19e-05	13	34	2	25127144
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	KCNN2 FBXL17 ZFHX3 TNRC18 CDK13 SLC22A3 LRP8 SHB	7.43e-05	1489	34	8	28611215
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	KDM3B TNRC18 SH3RF1 ZFP36L2 TRIM28 CDK13 ZNF503	8.14e-05	1105	34	7	35748872
Pubmed	Recruitment of 5' Hoxa genes in the allantois is essential for proper extra-embryonic function in placental mammals.	HOXA11 EVX1	1.10e-04	16	34	2	22219351
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	KDM3B DIDO1 ZFHX3 OTX1 ZFP36L2 TRIM28	1.19e-04	808	34	6	20412781
Pubmed	Selective expression of Bhlhb5 in subsets of early-born interneurons and late-born association neurons in the spinal cord.	EVX1 BHLHE22	1.25e-04	17	34	2	17219401
Pubmed	The transcription factor Zfp503 promotes the D1 MSN identity and represses the D2 MSN identity.	SP8 ZNF503	1.25e-04	17	34	2	36081908
Pubmed	Neuron-specific inactivation of Wt1 alters locomotion in mice and changes interneuron composition in the spinal cord.	EVX1 BHLHE22	1.41e-04	18	34	2	30456369
Pubmed	Tle4 controls both developmental acquisition and early post-natal maturation of corticothalamic projection neuron identity.	BHLHE22 SHB	1.57e-04	19	34	2	37561632
Pubmed	Transcriptional regulation of cortical neuron migration by POU domain factors.	OTX1 LRP8	1.74e-04	20	34	2	11859196
Pubmed	An atlas of combinatorial transcriptional regulation in mouse and man.	HOXA11 SP8 TRIM28 ZIC2 TBX2 PITX3	1.86e-04	877	34	6	20211142
Pubmed	Embryonic temporal-spatial delineation of excitatory spinal V3 interneuron diversity.	SP8 BHLHE22	2.12e-04	22	34	2	38160393
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	HOXA11 DIDO1 RCOR1 OTX1 CKAP4 TRIM28 CDK13	2.16e-04	1294	34	7	30804502
Pubmed	Tbr1 regulates differentiation of the preplate and layer 6.	OTX1 LRP8	2.32e-04	23	34	2	11239428
Pubmed	Nuclear receptors TR2 and TR4 recruit multiple epigenetic transcriptional corepressors that associate specifically with the embryonic β-type globin promoters in differentiated adult erythroid cells.	RCOR1 TRIM28	2.32e-04	23	34	2	21670149
Pubmed	Tbx2 and Tbx3 regulate cell fate progression of the otic vesicle for inner ear development.	OTX1 TBX2	2.32e-04	23	34	2	36521641
Pubmed	cDNAs with long CAG trinucleotide repeats from human brain.	TNRC18 BHLHE22	2.32e-04	23	34	2	9225980
Pubmed	The formation of the thumb requires direct modulation of Gli3 transcription by Hoxa13.	HOXA11 TBX2	2.53e-04	24	34	2	31896583
Pubmed	LRP2 Acts as SHH Clearance Receptor to Protect the Retinal Margin from Mitogenic Stimuli.	OTX1 ZIC2	2.97e-04	26	34	2	26439398
Pubmed	Transcriptional regulatory networks in epiblast cells and during anterior neural plate development as modeled in epiblast stem cells.	OTX1 ZIC2	2.97e-04	26	34	2	22992956
Pubmed	Retinoic acid deficiency impairs the vestibular function.	OTX1 TBX2	2.97e-04	26	34	2	23536097
Pubmed	A genome-wide RNAi screen identifies multiple synthetic lethal interactions with the Ras oncogene.	KDM3B DIDO1 TNRC18 C4orf54	2.98e-04	331	34	4	19490893
Pubmed	BMP receptor 1b is required for axon guidance and cell survival in the developing retina.	ZIC2 TBX2	3.21e-04	27	34	2	12654290
Pubmed	Distinct populations of GABAergic neurons in mouse rhombomere 1 express but do not require the homeodomain transcription factor PITX2.	EVX1 BHLHE22	3.21e-04	27	34	2	21925604
Pubmed	Rhombomere-specific analysis reveals the repertoire of genetic cues expressed across the developing hindbrain.	BHLHE22 ZNF503	3.21e-04	27	34	2	19208226
Pubmed	Gene expression is dynamically regulated in retinal progenitor cells prior to and during overt cellular differentiation.	OTX1 BHLHE22	3.21e-04	27	34	2	24148613
Pubmed	The cellular and molecular landscape of hypothalamic patterning and differentiation from embryonic to late postnatal development.	SP8 ZFHX3	3.45e-04	28	34	2	32868762
Pubmed	Temporal analysis of enhancers during mouse cerebellar development reveals dynamic and novel regulatory functions.	RCOR1 BHLHE22	3.45e-04	28	34	2	35942939
Pubmed	Genome-wide association study of bipolar disorder accounting for effect of body mass index identifies a new risk allele in TCF7L2.	FBXL17 MARCKS	3.45e-04	28	34	2	24322204
Pubmed	A novel role for Dbx1-derived Cajal-Retzius cells in early regionalization of the cerebral cortical neuroepithelium.	SP8 BHLHE22	3.45e-04	28	34	2	20668538
Pubmed	Zfhx3 is required for the differentiation of late born D1-type medium spiny neurons.	ZFHX3 ZNF503	3.70e-04	29	34	2	31491374
Pubmed	Single cell transcriptomics reveals spatial and temporal dynamics of gene expression in the developing mouse spinal cord.	ZFHX3 EVX1	3.70e-04	29	34	2	30846445
Pubmed	Genome-wide characterisation of Foxa1 binding sites reveals several mechanisms for regulating neuronal differentiation in midbrain dopamine cells.	OTX1 PITX3	3.97e-04	30	34	2	25804738
Pubmed	SMYD3 Impedes Small Cell Lung Cancer Sensitivity to Alkylation Damage through RNF113A Methylation-Phosphorylation Cross-talk.	RCOR1 TNRC18 TRIM28 CDK13 TBX2	4.13e-04	655	34	5	35819319
Pubmed	Activation of Wnt signaling reduces ipsilaterally projecting retinal ganglion cells in pigmented retina.	OTX1 ZIC2	4.24e-04	31	34	2	30254141
Pubmed	TTF-1/NKX2-1 binds to DDB1 and confers replication stress resistance to lung adenocarcinomas.	ZFHX3 RCOR1 TRIM28	4.43e-04	152	34	3	28192407
Pubmed	Dlx1/2-dependent expression of Meis2 promotes neuronal fate determination in the mammalian striatum.	SP8 ZNF503	4.52e-04	32	34	2	35156680
Pubmed	Selective neuronal lineages derived from Dll4-expressing progenitors/precursors in the retina and spinal cord.	EVX1 BHLHE22	4.81e-04	33	34	2	25179941
Pubmed	Gfi1b regulates the level of Wnt/β-catenin signaling in hematopoietic stem cells and megakaryocytes.	KDM3B RCOR1	5.10e-04	34	34	2	30894540
Pubmed	Roles for Dicer1 in the patterning and differentiation of the optic cup neuroepithelium.	OTX1 BHLHE22	5.10e-04	34	34	2	21138975
Pubmed	Deficient FGF signaling causes optic nerve dysgenesis and ocular coloboma.	OTX1 ZNF503	5.72e-04	36	34	2	23720040
Pubmed	BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.	CKAP4 SH3RF1 TRIM28 MARCKS SHB	5.88e-04	708	34	5	39231216
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	KDM3B DIDO1 RCOR1 TNRC18 CDK13 ZNF503	6.31e-04	1103	34	6	34189442
Pubmed	Aurora kinase A regulates Survivin stability through targeting FBXL7 in gastric cancer drug resistance and prognosis.	ZFHX3 SOX30	6.38e-04	38	34	2	28218735
Pubmed	Delayed maturation and migration of excitatory neurons in the juvenile mouse paralaminar amygdala.	SP8 BHLHE22	6.38e-04	38	34	2	38086370
Pubmed	Cross-linking mass spectrometry reveals the structural topology of peripheral NuRD subunits relative to the core complex.	ZFHX3 RCOR1	6.38e-04	38	34	2	33283408
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	ZFHX3 RCOR1 CKAP4 TRIM28 ZIC2 TBX2	6.71e-04	1116	34	6	31753913
Pubmed	Transcriptional network orchestrating regional patterning of cortical progenitors.	SP8 TRIM28	6.72e-04	39	34	2	34921112
Pubmed	Diverse spinal commissural neuron populations revealed by fate mapping and molecular profiling using a novel Robo3Cre mouse.	EVX1 BHLHE22	7.07e-04	40	34	2	31152445
Pubmed	Deterministic and stochastic allele specific gene expression in single mouse blastomeres.	ZFHX3 RCOR1 OTX1 TBX2	7.56e-04	424	34	4	21731673
Pubmed	OTX2 Transcription Factor Controls Regional Patterning within the Medial Ganglionic Eminence and Regional Identity of the Septum.	SP8 OTX1	7.79e-04	42	34	2	26166575
Pubmed	Identification of genes expressed preferentially in the developing peripheral margin of the optic cup.	OTX1 ZIC2	7.79e-04	42	34	2	19449303
Pubmed	The DNA sequence of human chromosome 7.	HOXA11 EVX1 TNRC18 CDK13	8.75e-04	441	34	4	12853948
Interaction	GSC interactions	ZFHX3 TNRC18 PRDM6 ZNF503	1.20e-05	87	33	4	int:GSC
Cytoband	7p15.2	HOXA11 EVX1	4.72e-04	43	34	2	7p15.2
Cytoband	Ensembl 112 genes in cytogenetic band chr7p15	HOXA11 EVX1	2.57e-03	101	34	2	chr7p15
GeneFamily	Ataxins\|Trinucleotide repeat containing	TNRC18 BHLHE22	6.31e-04	25	27	2	775
GeneFamily	HOXL subclass homeoboxes	HOXA11 EVX1	2.72e-03	52	27	2	518
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	SP8 ZFHX3 PRDM6 ZIC2 ZNF503	3.80e-03	718	27	5	28
GeneFamily	Ring finger proteins	SH3RF1 ZFP36L2 TRIM28	7.77e-03	275	27	3	58
GeneFamily	PHD finger proteins	DIDO1 TRIM28	7.93e-03	90	27	2	88
GeneFamily	PRD class homeoboxes and pseudogenes	OTX1 PITX3	8.28e-03	92	27	2	521
Coexpression	BENPORATH_EED_TARGETS	ZFHX3 EVX1 OTX1 SLC22A3 BHLHE22 ZIC2 ZNF503 TBX2 PITX3	5.84e-06	1059	34	9	M7617
Coexpression	MEISSNER_BRAIN_HCP_WITH_H3K4ME3_AND_H3K27ME3	SP8 OTX1 ZFP36L2 SLC22A3 BHLHE22 ZIC2 ZNF503 TBX2 PITX3	6.54e-06	1074	34	9	M1941
Coexpression	BENPORATH_ES_WITH_H3K27ME3	ZFHX3 EVX1 OTX1 TRIM28 SLC22A3 BHLHE22 ZNF503 TBX2 PITX3	8.85e-06	1115	34	9	M10371
Coexpression	RODRIGUES_THYROID_CARCINOMA_POORLY_DIFFERENTIATED_DN	KDM3B FBXL17 ZFHX3 SH3RF1 ZFP36L2 CDK13 LRP8	6.65e-05	807	34	7	M16651
Coexpression	MIKKELSEN_NPC_HCP_WITH_H3K27ME3	HOXA11 SP8 EVX1 SLC22A3 FOXB2	7.80e-05	345	34	5	M2009
Coexpression	MIKKELSEN_NPC_HCP_WITH_H3K27ME3	HOXA11 SP8 EVX1 SLC22A3 FOXB2	8.02e-05	347	34	5	MM860
Coexpression	MEISSNER_NPC_HCP_WITH_H3K4ME2_AND_H3K27ME3	SP8 EVX1 PRDM6 SLC22A3 FOXB2	8.35e-05	350	34	5	M1949
Coexpression	MEISSNER_NPC_HCP_WITH_H3K4ME2_AND_H3K27ME3	SP8 EVX1 PRDM6 SLC22A3 FOXB2	9.17e-05	357	34	5	MM828
Coexpression	GSE45365_NK_CELL_VS_CD8A_DC_DN	KCNN2 HOXA11 TMEM200C TBX2	1.25e-04	199	34	4	M10029
Coexpression	BENPORATH_PRC2_TARGETS	ZFHX3 OTX1 BHLHE22 ZNF503 TBX2 PITX3	1.69e-04	650	34	6	M8448
ToppCell	5'-GW_trimst-2-LargeIntestine-Mesenchymal-immature_mesenchymal_cell-Mesoderm_2_(ZEB2+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HOXA11 CKAP4 C4orf54 ZNF503	1.19e-05	192	33	4	f053b89bfd6048c227667ff01c38df7c51d8a496
ToppCell	wk_08-11-Mesenchymal\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	PRDM6 MARCKS ZNF503 TBX2	1.40e-05	200	33	4	91416639e69621c5b36eebf061d81bccfe66f135
ToppCell	Substantia_nigra\|World / BrainAtlas - Mouse McCarroll V32	ZFHX3 ZNF503 PITX3	8.39e-05	115	33	3	18174b8d57d444fab1e9d2b13d22939c83c958e0
ToppCell	(01)_Cycling_Basal_(homeostasis)-(4)_1wkpi\|(01)_Cycling_Basal_(homeostasis) / shred by cell type and Timepoint	HOXA11 SP8 ELFN2	1.00e-04	122	33	3	b2a070939c0660c82a1130ef423fd627e9e087ab
ToppCell	frontal_cortex-Non-neuronal-leptomeningeal_cell-VLMC-VLMC_Spp1_Hs3st6\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	PRDM6 ZIC2 ZNF503	1.02e-04	123	33	3	64a2d7e40d9c948a9ccaf61c465fb2207e0b7ab8
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L5_PT\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	KCNN2 OTX1 BHLHE22	1.50e-04	140	33	3	7cc891d676555609add6fc7880735d948a2ad801
ToppCell	facs-Trachea-18m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l20-23\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SP8 CCDC177 ELFN2	1.63e-04	144	33	3	e9d62f202f0fa8747961036ef0eafed91fe8a42f
ToppCell	Dendritic_Cells-Donor_03\|World / lung cells shred on cell class, cell subclass, sample id	ZFP36L2 TMEM200C MARCKS	1.99e-04	154	33	3	65013f696da623d37f1e3447a294dfb3c31ae93b
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-4_VIP_CHRNA2\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SP8 TMEM200C SLC22A3	2.03e-04	155	33	3	523a821963d2aecb67da7133a9a4b3bc33309b58
ToppCell	Children_(3_yrs)-Mesenchymal-chondrocyte\|Children_(3_yrs) / Lineage, Cell type, age group and donor	PRDM6 SOX30 TBX2	2.11e-04	157	33	3	f147e24f2ece82e1c54750868954d09b3c461804
ToppCell	Children_(3_yrs)-Mesenchymal-chondrocyte-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	PRDM6 SOX30 TBX2	2.15e-04	158	33	3	e5636c0b608d68bd426a2b446ac508e4512e86a4
ToppCell	TCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_Tubular-6\|TCGA-Stomach / Sample_Type by Project: Shred V9	SH3RF1 ELFN2 LRP8	2.19e-04	159	33	3	655c0749c238bd68cb797adb83e25a23b8a3cc9d
ToppCell	RV-13._Vascular_Smooth_Muscle\|World / Chamber and Cluster_Paper	ZFHX3 SLC22A3 TBX2	2.23e-04	160	33	3	29c9b4770d0e73d59cffc7937b179484c76b6dcc
ToppCell	droplet-Marrow-BM-30m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZFHX3 EVX1 CKAP4	2.48e-04	166	33	3	019d365df44c3bbd88c1f4bdceb3de0ff76d3e8d
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Degenerative_Podocyte\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CKAP4 TRIM28 TMEM200C	2.48e-04	166	33	3	dc443a3327dc8f9a0d808c3c6e06b0834d45f5c2
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial-Lgr5+_amplifying_undifferentiated_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZFHX3 SH3RF1 MARCKS	2.57e-04	168	33	3	d69452e2cfeb74023b5cf3d09064d7dcad0008ec
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ZFHX3 LRP8 SHB	2.57e-04	168	33	3	7abaddbcc55e44653d54aa15464266aa6bd5c9d2
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2-Exc_L6_FEZF2_ETV4\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ZFHX3 ZNF503 SHB	2.61e-04	169	33	3	ccb7b2daa65cb5f4c1e7a48b3bcdf0cb8f7675c3
ToppCell	368C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	ELFN2 TBX2 PITX3	2.66e-04	170	33	3	054360a3b05f5e41221c98b122d241b1affad26a
ToppCell	368C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)-\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	ELFN2 TBX2 PITX3	2.66e-04	170	33	3	f0b0d2d0402de3ed7322284a599646db43475761
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ZFHX3 LRP8 SHB	2.66e-04	170	33	3	417b77c12a7982b1ce4b4bc57f30335d261220f5
ToppCell	LV-13._Vascular_Smooth_Muscle\|LV / Chamber and Cluster_Paper	ZFHX3 SLC22A3 TBX2	2.71e-04	171	33	3	e99ecae66530d1ae09330cee408c8f3950b87e67
ToppCell	droplet-Thymus-nan-18m-Lymphocytic-DN3_thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZFP36L2 MARCKS SLC22A3	2.80e-04	173	33	3	5d7c53c6d1cdd385e44b79b82faec901747d1736
ToppCell	droplet-Thymus-nan-18m-Lymphocytic-Double_negative_thymocyte,_DN3_(Cd8-,_Cd4-),_some_express_pre_TCR_alpha\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZFP36L2 MARCKS SLC22A3	2.85e-04	174	33	3	9eab43885496b8586f8ec5b4bcb1fd5b209218e5
ToppCell	COVID-19-kidney-REN+Pericyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	HOXA11 EVX1 TBX2	2.85e-04	174	33	3	8393f0b43c767839c1630bcb952d62b42efc788d
ToppCell	facs-Heart-RV-18m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCNN2 PRDM6 TBX2	2.90e-04	175	33	3	d8e385320f554d974538b7cdc4f8e4767f1455f2
ToppCell	COVID-19-Heart-VSMC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ZFHX3 SLC22A3 TBX2	2.90e-04	175	33	3	1125f0d3a5b2388fa77a820dea0288e824d84a82
ToppCell	facs-Heart-RV-18m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCNN2 PRDM6 TBX2	2.90e-04	175	33	3	cf15465855602ba135752c18755e3e058dbd42ec
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ZFHX3 LRP8 SHB	2.95e-04	176	33	3	e4b21fd6a5e0c5950f27c3e1868318e48330ae5e
ToppCell	E18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_prolif\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FBXL17 ZFHX3 PRDM6	2.99e-04	177	33	3	4553ee8cd9c24db6511b09fe49ed11a89e7cde9e
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ZFHX3 LRP8 SHB	2.99e-04	177	33	3	4c069f0d044a96118090b85ca592a21d6b5d9399
ToppCell	3'-GW_trimst-2-LargeIntestine-Mesenchymal-Pericytes-Immature_pericyte\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ZFHX3 MARCKS TBX2	3.04e-04	178	33	3	e5e4742e35c3d90f82b830d77bdbdc45828c7deb
ToppCell	COVID-19-Heart-VSMC\|Heart / Disease (COVID-19 only), tissue and cell type	ZFHX3 SLC22A3 TBX2	3.09e-04	179	33	3	a69ad6912b5c10bb9f9d800f724c792341e9bab1
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_FAM95C\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ZFHX3 LRP8 SHB	3.09e-04	179	33	3	f65889bf1e41396979cce44a5e63f49dea2bbd9b
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ZFHX3 LRP8 SHB	3.15e-04	180	33	3	e8841ef1239f9ee73ac4f4e11faca0742694f368
ToppCell	facs-Heart-RA-3m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZFHX3 BHLHE22 TBX2	3.20e-04	181	33	3	429df38438d5a7ff490c9ede34b69e2970c7ded2
ToppCell	Fetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	PRDM6 TMEM200C TBX2	3.20e-04	181	33	3	25915e2500430a902db37d79a749ce2990b69810
ToppCell	VE-matDC-\|VE / Condition, Cell_class and T cell subcluster	MARCKS BHLHE22 PITX3	3.20e-04	181	33	3	6252184ef098b911df50be4fe1b5565849a5b6b8
ToppCell	facs-Heart-RA-3m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZFHX3 BHLHE22 TBX2	3.20e-04	181	33	3	395cf5aa2d89b05328ab516b8c89401020b6d830
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L2-5_VIP_TOX2\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SP8 TMEM200C SLC22A3	3.20e-04	181	33	3	35bcdcd2651149692e5b150e887c0f450c81d2d4
ToppCell	VE-matDC\|VE / Condition, Cell_class and T cell subcluster	MARCKS BHLHE22 PITX3	3.20e-04	181	33	3	982fd96ef75bc9ab2c2f4970c01b76ba7a164871
ToppCell	3'-Broncho-tracheal-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell-SM_activated_stress_response\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ZFHX3 BHLHE22 TBX2	3.25e-04	182	33	3	1c1a687f728341c209b048b6715bcddd0ac20069
ToppCell	3'-Broncho-tracheal-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell-SM_activated_stress_response-SM_activated_stress_response_L.2.3.0.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ZFHX3 BHLHE22 TBX2	3.25e-04	182	33	3	97bb07478f56a937b490fba121ee603db64134a1
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM2_(12)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	ZFHX3 AKIRIN2 PRDM6	3.30e-04	183	33	3	e84539978ab4de42e19186aed00f24bb50cbc21f
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ZFHX3 LRP8 SHB	3.30e-04	183	33	3	65f2a5895d166189a095cf7ea9dda171f0419b08
ToppCell	wk_20-22-Mesenchymal-Myofibro_&_SMC-Myofibro_3\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	PRDM6 TMEM200C ZNF503	3.30e-04	183	33	3	f4ea7113ce9099222743d9ff02388d3d8a9e987b
ToppCell	COVID-19-Heart-Pericyte\|Heart / Disease (COVID-19 only), tissue and cell type	ZFHX3 SH3RF1 TBX2	3.35e-04	184	33	3	21790cdfa3b4036ad413fd44b94e31563116f25f
ToppCell	Primary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1_FGFR3_FOS\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	OTX1 ZFP36L2 ZIC2	3.35e-04	184	33	3	22c18964818fc9c8f18051f836d718937b0d8d12
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	ZFHX3 ZFP36L2 PRDM6	3.41e-04	185	33	3	1ac6a32cc56d5d819649bdd99518e2ead0eead4c
ToppCell	droplet-Liver-Hepatocytes-24m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SH3RF1 CDK13 ZNF503	3.46e-04	186	33	3	90d53c2597a9f3a2b39afba75adfc54f1ca0a4db
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ZFHX3 PRDM6 TBX2	3.46e-04	186	33	3	4780af76237d7af2abbe2d8d5530cdf53e3ed0b7
ToppCell	droplet-Liver-Hepatocytes-24m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SH3RF1 CDK13 ZNF503	3.46e-04	186	33	3	2cae34336f184f971f7c8684cc27c23a4e7369ed
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ZFHX3 PRDM6 TBX2	3.46e-04	186	33	3	a95744b8649096bd7cfc3591a02841fa411085b3
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	ZFHX3 ZFP36L2 PRDM6	3.46e-04	186	33	3	7def03dd856b765bd3f493288641981c4f7fd26e
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PRDM6 BHLHE22 TBX2	3.46e-04	186	33	3	5473283fb95cee556b1f6934cf72169b676b5bcc
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SP8 TMEM200C SLC22A3	3.52e-04	187	33	3	ae2ee6f8e5c37cb88a67f3e742cf86e57657bfaf
ToppCell	P15-Endothelial-unknown_endothelial_cell-endothelial_unknown_1\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	ZFHX3 MARCKS TBX2	3.52e-04	187	33	3	60f41b1f1b656d211b80398aa2cf0ac0cdad9372
ToppCell	P15-Endothelial-unknown_endothelial_cell\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	ZFHX3 MARCKS TBX2	3.52e-04	187	33	3	d543ddc63f864b6d0982c4ff652af174af085c4a
ToppCell	E12.5-Mesenchymal\|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	MARCKS ZNF503 TBX2	3.57e-04	188	33	3	9778dadc2bd7ded3a723e717d1c8cd3160e99c6c
ToppCell	-Donor_07\|World / lung cells shred on cell class, cell subclass, sample id	BHLHE22 TBX2 PITX3	3.57e-04	188	33	3	038f48e8daaeb72716e975d22a6b004a90654960
ToppCell	P15-Endothelial-capillary_endothelial_cell-capillary_endothelial_cell_of_alveolus\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	ZFHX3 MARCKS TBX2	3.57e-04	188	33	3	c0a03e33027f52b5c25ffbc8f822128e5160ed20
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM2_(12)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	ZFHX3 AKIRIN2 PRDM6	3.57e-04	188	33	3	3004e961d214919e08c7cd5f10c3de5cf85b35a3
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_myocytic\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	ZFHX3 AKIRIN2 PRDM6	3.63e-04	189	33	3	f75cebd4c3e54e297557449ba67ccc8d1a2a14f5
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ZFHX3 PRDM6 TBX2	3.63e-04	189	33	3	2cfb4d12f75678d1619f4743838a0e954bd57761
ToppCell	droplet-Liver-Hepatocytes-24m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SH3RF1 ZNF503 TBX2	3.63e-04	189	33	3	ce5b3d53c9a5457a5a02b221dee18334b5eaf8b7
ToppCell	LPS_only-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ZFHX3 PRDM6 TBX2	3.63e-04	189	33	3	975e7aa3b862a8b07c2ab8426a14f5cc54998aca
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ZFHX3 PRDM6 TBX2	3.63e-04	189	33	3	127ad2ba3e794df8cce2eee3e4171bccb5aad51b
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ZFHX3 PRDM6 TBX2	3.63e-04	189	33	3	7ab1cfc1657277858339f7258a0c4ae9cb42fdf8
ToppCell	wk_15-18-Mesenchymal-Myofibro_&_SMC-Myofibro_1\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	PRDM6 ZNF503 TBX2	3.68e-04	190	33	3	d24af6af3271e34afab744352afd28be8a7cc5c3
ToppCell	5'-GW_trimst-2-LargeIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HOXA11 PRDM6 ZNF503	3.68e-04	190	33	3	c01a8bfb9fbc0e6f37d7e9be25512eda63acabbc
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ZFHX3 PRDM6 TBX2	3.68e-04	190	33	3	73d94fbae92029745989a8712eed8b99fd84c193
ToppCell	E16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ZFHX3 MARCKS TBX2	3.68e-04	190	33	3	106862ef44fcaa0971c3ba0147d13eb08015ca77
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-3.5_mon-Neuronal-Immature_INs\|3.5_mon / Sample Type, Dataset, Time_group, and Cell type.	SP8 ZFHX3 MARCKS	3.68e-04	190	33	3	842760bfe0a52e67bad800efa7d99448a4a23ebb
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ZFHX3 PRDM6 TBX2	3.74e-04	191	33	3	7853ac7dff649150e6ff27cd4c8cf7c1fc034ed4
ToppCell	facs-Lung-3m-Mesenchymal-fibroblast-alveolar_fibroblast\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PRDM6 SLC22A3 TBX2	3.74e-04	191	33	3	beb5bb42bd53bce01339da9110d374901548793c
ToppCell	facs-Lung-3m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l49\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PRDM6 SLC22A3 TBX2	3.74e-04	191	33	3	6609d85fd2577633dcc067507304a6f9e5865ca3
ToppCell	LPS_only-Stromal_mesenchymal-Lung_smooth_muscle\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ZFHX3 PRDM6 TBX2	3.74e-04	191	33	3	08042952431ca1a6fd7dfc13f36eb28643979598
ToppCell	E16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ZFHX3 MARCKS TBX2	3.80e-04	192	33	3	430ef714bf2544d32f3fd96a55af010f79aa9be0
ToppCell	wk_08-11-Mesenchymal-Myofibro_&_SMC-Early_airway_SMC_1\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	ZFHX3 AKIRIN2 PRDM6	3.80e-04	192	33	3	7ae3e1ca8bfc078c0e12a1595ecb0e343dab5d2f
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SP8 TMEM200C SLC22A3	3.80e-04	192	33	3	3abee376c37c3646da33ac381aa63d50a01607a6
ToppCell	PND28-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ZFHX3 MARCKS TBX2	3.80e-04	192	33	3	9a1aeac3ecf31f865a23d8ee15a82aef31779089
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ZFHX3 PRDM6 TBX2	3.80e-04	192	33	3	992d08092edbc68c47b945deb8708379738c239a
ToppCell	PND28-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2-CAP2_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ZFHX3 MARCKS TBX2	3.80e-04	192	33	3	53d438e35c14e7656585942b788459e6d843c555
ToppCell	Endothelial-Endothelial-B\|Endothelial / shred on cell class and cell subclass (v4)	ZFHX3 MARCKS TBX2	3.80e-04	192	33	3	f8d7bd81e031d09a557722627c2f6180811cc6ab
ToppCell	PBMC-Control-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_4\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	RCOR1 CKAP4 MARCKS	3.80e-04	192	33	3	0219093e7921a0db78053aee13ec480b520f5662
ToppCell	PBMC-Control-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_4\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	RCOR1 CKAP4 MARCKS	3.80e-04	192	33	3	f14ee74ac3275601749a23c5efe39c2413a62e1a
ToppCell	facs-Lung-EPCAM-3m-Mesenchymal\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRDM6 SLC22A3 TBX2	3.86e-04	193	33	3	abdfb8b1dbdcb424042e21017a9e829fced4457e
ToppCell	E15.5-Mesenchymal\|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	PRDM6 MARCKS TBX2	3.86e-04	193	33	3	22a9f5b61f197757f72840b9cb849cdb20430e72
ToppCell	21-Trachea-Epithelial-Epithelial\|Trachea / Age, Tissue, Lineage and Cell class	KCNN2 SLC22A3 ZIC2	3.86e-04	193	33	3	9a8bb44a37f3202e3123a6680bd5545dc91a6d40
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM1_(8)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	ZFHX3 PRDM6 TBX2	3.86e-04	193	33	3	e2b455387d1de7812305200a2041a0f4759a6f54
ToppCell	Control-Stromal-Myofibroblast\|Control / Disease state, Lineage and Cell class	PRDM6 BHLHE22 TBX2	3.97e-04	195	33	3	ffcf76cd72e43d8cf1058a49c76e0956065038bc
ToppCell	Bronchial_Biopsy-Mesenchymal-Fibroblasts\|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X	PRDM6 BHLHE22 TBX2	3.97e-04	195	33	3	5870b2956d50d6550a3174a220a6cc70c5538d70
ToppCell	3'-Parenchyma_lung-Endothelial-Blood_vessel_EC-capillary_endothelial_cell-EC_aerocyte_capillary-EC_aerocyte_capillary_L.2.0.1.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	KCNN2 MARCKS TBX2	3.97e-04	195	33	3	e8992c549dad9a88d2b8d01039a8d02a950b29b4
ToppCell	tumor_Lung-Fibroblasts-Smooth_muscle_cells\|tumor_Lung / Location, Cell class and cell subclass	PRDM6 ZNF503 TBX2	3.97e-04	195	33	3	ea9ff25020c2fcd1bab80e1829af0f4e4777de8b
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature3_(17)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	PRDM6 MARCKS TBX2	3.97e-04	195	33	3	1cdf5f296029ae424d9dba42e86a6d111e4896e6
ToppCell	PCW_05-06-Mesenchymal\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	PRDM6 MARCKS TBX2	4.03e-04	196	33	3	dca52c57ba35d9395cdbca8b881f12ece721b10f
ToppCell	367C-Fibroblasts-Fibroblast-C_(Myofibroblast)-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	ZFP36L2 MARCKS TBX2	4.03e-04	196	33	3	6730743cf088c419ccc2d28765769fc09d3ba6a7
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	PRDM6 MARCKS TBX2	4.03e-04	196	33	3	1450cb69c5bf469e97c03bf1890f6f7c54165b8a
ToppCell	Bronchial_Biopsy-Mesenchymal\|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X	PRDM6 BHLHE22 TBX2	4.03e-04	196	33	3	d37d821229dce716a05c2a5865415e10f79032de
ToppCell	COVID-19-lung-Pericytes/_Smooth_Muscle\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ZFHX3 PRDM6 TBX2	4.03e-04	196	33	3	754a3613340932563cd8424d775e18b93c3a1aaa
Drug	Trichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A_EA	DIDO1 ZFHX3 ZFP36L2 CDK13 LRP8 TBX2	1.59e-07	172	33	6	1072_DN
Drug	SAHA; Down 200; 10uM; MCF7; HT_HG-U133A_EA	DIDO1 ZFHX3 ZFP36L2 CDK13 LRP8 TBX2	1.76e-07	175	33	6	1058_DN
Disease	response to darapladib, Diarrhea	SP8 FOXB2	1.53e-04	16	34	2	EFO_0008395, HP_0002014
Disease	prostate carcinoma	SP8 ZFHX3 RCOR1 OTX1 SH3RF1 SLC22A3	4.86e-04	891	34	6	EFO_0001663
Disease	Prostatic Neoplasms	ZFHX3 ZFP36L2 SLC22A3 ZIC2 PITX3	6.58e-04	616	34	5	C0033578
Disease	Malignant neoplasm of prostate	ZFHX3 ZFP36L2 SLC22A3 ZIC2 PITX3	6.58e-04	616	34	5	C0376358
Disease	unipolar depression, systolic blood pressure	HOXA11 EVX1	7.06e-04	34	34	2	EFO_0003761, EFO_0006335
Disease	atrial fibrillation	KCNN2 ZFHX3 PRDM6 PITX3	8.46e-04	371	34	4	EFO_0000275
Disease	lung non-small cell carcinoma (is_marker_for)	KDM3B ZFHX3 SOX30	9.69e-04	169	34	3	DOID:3908 (is_marker_for)
Disease	hepatocellular carcinoma (is_implicated_in)	ZFHX3 CDK13 SOX30	1.18e-03	181	34	3	DOID:684 (is_implicated_in)
Disease	breast cancer (is_marker_for)	KDM3B ZFHX3 CDK13	1.26e-03	185	34	3	DOID:1612 (is_marker_for)
Disease	risk-taking behaviour	FBXL17 ZFHX3 OTX1 BHLHE22 LRP8	1.71e-03	764	34	5	EFO_0008579
Disease	mean arterial pressure	HOXA11 ZFHX3 PRDM6 TBX2	2.51e-03	499	34	4	EFO_0006340
Disease	autosomal dominant compelling helio-ophthalmic outburst syndrome	ZFHX3 SH3RF1	3.57e-03	77	34	2	EFO_0007887
Disease	pulse pressure measurement	FBXL17 ZFHX3 PRDM6 SLC22A3 TBX2 SHB	4.71e-03	1392	34	6	EFO_0005763
Disease	hepatocellular carcinoma (is_marker_for)	ZFHX3 CKAP4 SOX30	4.98e-03	301	34	3	DOID:684 (is_marker_for)
Disease	age at menopause	FBXL17 DIDO1 TNRC18	5.02e-03	302	34	3	EFO_0004704
Disease	social interaction measurement	FBXL17 OTX1	5.27e-03	94	34	2	EFO_0009592
Disease	creatinine measurement	FBXL17 ZFHX3 ZFP36L2 SLC22A3 TBX2	5.33e-03	995	34	5	EFO_0004518
Disease	alcohol use disorder measurement, alcohol consumption measurement	SP8 ZFHX3	5.60e-03	97	34	2	EFO_0007878, EFO_0009458
Disease	diet measurement	KDM3B SP8 ZFHX3 OTX1 SH3RF1	6.64e-03	1049	34	5	EFO_0008111
Disease	schizophrenia, intelligence, self reported educational attainment	KCNN2 FBXL17 SH3RF1	7.31e-03	346	34	3	EFO_0004337, EFO_0004784, MONDO_0005090
Disease	sleep duration	KDM3B KCNN2 SH3RF1	8.27e-03	362	34	3	EFO_0005271

Protein segments in the cluster

Peptide	Gene	Start	Entry
SAAAAAAAASSSASC	CKAP4	86	Q07065
AAASPLSAAAATAAS	AKIRIN2	36	Q53H80
ISAASLPSSAAAAAA	BHLHE22	316	Q8NFJ8
APRAAAASDFTCAST	EVX1	361	P49640
TAAAAAAAAAASSSC	CDK13	66	Q14004
SAAAASAAASAACAS	RCOR1	26	Q9UKL0
SAAASAACASPAATA	RCOR1	31	Q9UKL0
AACASPAATAASGAA	RCOR1	36	Q9UKL0
PAATAASGAAASSAS	RCOR1	41	Q9UKL0
ASGAAASSASAAAAS	RCOR1	46	Q9UKL0
ASSASAAAASAAAAP	RCOR1	51	Q9UKL0
SAAAAAAAAAASTSG	FOXB2	251	Q5VYV0
ASSPSAAAAAAAAVS	KCNN2	46	Q9H2S1
AAAAAAAAVSSSAPE	KCNN2	51	Q9H2S1
AASASASAPAAAAAS	KDM3B	21	Q7LBC6
SAAAAAAATGAPATS	HOXA11	176	P31270
SASSSSANPAAAAAA	OTX1	141	P32242
SSASSCAAAAAAAAL	PRDM6	91	Q9NQX0
LSSAAAAAAAAASAS	FBXL17	121	Q9UF56
AAAAAAASASSPASC	FBXL17	126	Q9UF56
PATAATTAAAASTAA	DIDO1	1286	Q9BTC0
PAAAAASSACAAPSQ	MARCKS	301	P29966
EPAASSASASASAAV	CCDC177	36	Q9NQR7
ASGAAAAAASSCGSA	C4orf54	501	D6RIA3
SASATSALSCADPLA	SLC22A3	101	O75751
SCPYASAAAAAAAAA	PITX3	236	O75364
SAAAAAAAAASSPYV	PITX3	241	O75364
GATSAPAACATASQF	LRP8	251	Q14114
QASSAASASCGPATA	SHB	46	Q15464
AAAAASSSSSAPAAA	TMEM200C	226	A6NKL6
RRAAAATAAAAASSC	TMEM200C	336	A6NKL6
ATAAAAASSCSSPAP	TMEM200C	341	A6NKL6
AASATLASSCGEAVA	SOX30	46	O94993
AAAAAALVSDSFSCG	SP8	76	Q8IXZ3
AAAAAAAAAAASSSP	SP8	106	Q8IXZ3
AGECSSAAAQSSTAP	SH3RF1	276	Q7Z6J0
NCSAASSRAASPASS	TNRC18	2601	O15417
AAAAAAASALPATSA	TBX2	581	Q13207
AASALPATSAAAAAA	TBX2	586	Q13207
PATSAAAAAAAAAGS	TBX2	591	Q13207
CAAAAAPSAARSASA	SCAND2P	181	Q9GZW5
AASASCAHDPAAAAA	ZNF503	446	Q96F45
SGAPTCCASAAAAAA	ZFP36L2	316	P47974
AAASAAAASAASGSP	TRIM28	6	Q13263
PSAAASASASAAASS	TRIM28	36	Q13263
SNLSPAAAAAAAAAA	ZIC2	451	O95409
AVAAAAAAANISSSC	ZFHX3	776	Q15911
FECQSLPAAAAASSA	ELFN2	576	Q5R3F8