Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionhistone H3K4me/H3K4me2/H3K4me3 demethylase activity

KDM5B KDM5D KDM5A KDM5C

3.68e-106464GO:0034647
GeneOntologyMolecularFunctionhistone H3K4 demethylase activity

KDM5B KDM5D KDM5A KDM5C

1.71e-098464GO:0032453
GeneOntologyMolecularFunctionhistone H3 demethylase activity

KDM5B KDM5D KDM5A KDM5C

4.85e-0728464GO:0141052
GeneOntologyMolecularFunctionhistone demethylase activity

KDM5B KDM5D KDM5A KDM5C

7.41e-0731464GO:0032452
GeneOntologyMolecularFunctionprotein demethylase activity

KDM5B KDM5D KDM5A KDM5C

8.45e-0732464GO:0140457
GeneOntologyMolecularFunctionhistone binding

SMARCC1 KDM5B CHD2 CHD4 PRMT7 KDM5A CHD5

2.30e-06265467GO:0042393
GeneOntologyMolecularFunctiondemethylase activity

KDM5B KDM5D KDM5A KDM5C

3.13e-0644464GO:0032451
GeneOntologyMolecularFunction2-oxoglutarate-dependent dioxygenase activity

KDM5B KDM5D KDM5A KDM5C

1.51e-0565464GO:0016706
GeneOntologyMolecularFunctiondioxygenase activity

KDM5B KDM5D KDM5A KDM5C

7.60e-0598464GO:0051213
GeneOntologyMolecularFunctionATP-dependent chromatin remodeler activity

CHD2 CHD4 CHD5

8.42e-0537463GO:0140658
GeneOntologyMolecularFunctionhistone modifying activity

KDM5B KDM5D PRMT7 KDM5A KDM5C

1.77e-04229465GO:0140993
GeneOntologyMolecularFunctionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen

KDM5B KDM5D KDM5A KDM5C

1.02e-03194464GO:0016705
GeneOntologyMolecularFunctionmethylation-dependent protein binding

PHF20L1 KDM5A CHD5

1.09e-0388463GO:0140034
GeneOntologyMolecularFunctionmodification-dependent protein binding

PTPN6 PHF20L1 KDM5A CHD5

1.28e-03206464GO:0140030
GeneOntologyMolecularFunctionhydrolase activity, hydrolyzing O-glycosyl compounds

GBE1 MAN1A2 KLB

1.72e-03103463GO:0004553
GeneOntologyMolecularFunctionATP-dependent activity, acting on DNA

CHD2 CHD4 CHD5

3.12e-03127463GO:0008094
GeneOntologyMolecularFunctionhydrolase activity, acting on glycosyl bonds

GBE1 MAN1A2 KLB

4.44e-03144463GO:0016798
GeneOntologyBiologicalProcesschromatin remodeling

SMARCC1 KDM5B CHD2 CHD4 KDM5D PRMT7 KDM5A KDM5C CHD5

3.17e-05741469GO:0006338
MousePhenoabnormal pulmonary circulation

GPR4 CHD2 LMF1 MAN1A2 LOX

1.28e-0669395MP:0002295
MousePhenolung hemorrhage

GPR4 CHD2 LMF1 MAN1A2

1.27e-0552394MP:0001182
MousePhenoabnormal respiratory system physiology

USP25 DCAF15 NDST1 GPR4 PTPN6 CHD2 LMF1 MAN1A2 CLCA1 HAS3 LOX

2.27e-058973911MP:0002133
MousePhenoabnormal respiratory function

DCAF15 NDST1 GPR4 PTPN6 CHD2 MAN1A2 CLCA1

1.02e-04399397MP:0002327
DomainLys_sp_deMease-like_dom

KDM5B KDM5D KDM5A KDM5C

3.22e-114464IPR013637
DomainPLU-1

KDM5B KDM5D KDM5A KDM5C

3.22e-114464PF08429
Domainzf-C5HC2

KDM5B KDM5D KDM5A KDM5C

1.61e-105464PF02928
DomainZnf_C5HC2

KDM5B KDM5D KDM5A KDM5C

1.61e-105464IPR004198
DomainZinc_finger_PHD-type_CS

KDM5B CHD4 KDM5D PHF20L1 KDM5A KDM5C CHD5

2.13e-1065467IPR019786
DomainZnf_FYVE_PHD

KDM5B CHD4 RIMS1 KDM5D PHF20L1 KDM5A KDM5C CHD5

2.46e-09147468IPR011011
DomainZF_PHD_1

KDM5B CHD4 KDM5D PHF20L1 KDM5A KDM5C CHD5

3.45e-0996467PS01359
DomainJmjN

KDM5B KDM5D KDM5A KDM5C

6.69e-0910464SM00545
DomainJMJN

KDM5B KDM5D KDM5A KDM5C

6.69e-0910464PS51183
DomainJmjN

KDM5B KDM5D KDM5A KDM5C

6.69e-0910464PF02375
DomainJmjN

KDM5B KDM5D KDM5A KDM5C

6.69e-0910464IPR003349
DomainPHD

KDM5B CHD4 KDM5D KDM5A KDM5C CHD5

2.82e-0875466PF00628
DomainZnf_PHD-finger

KDM5B CHD4 KDM5D KDM5A KDM5C CHD5

3.86e-0879466IPR019787
Domain-

KDM5B KDM5D KDM5A KDM5C

4.31e-08154641.10.150.60
DomainBRIGHT

KDM5B KDM5D KDM5A KDM5C

4.31e-0815464SM00501
DomainARID_dom

KDM5B KDM5D KDM5A KDM5C

4.31e-0815464IPR001606
DomainARID

KDM5B KDM5D KDM5A KDM5C

4.31e-0815464PS51011
DomainARID

KDM5B KDM5D KDM5A KDM5C

4.31e-0815464PF01388
DomainPHD

KDM5B CHD4 KDM5D KDM5A KDM5C CHD5

7.93e-0889466SM00249
DomainZnf_PHD

KDM5B CHD4 KDM5D KDM5A KDM5C CHD5

9.07e-0891466IPR001965
DomainZF_PHD_2

KDM5B CHD4 KDM5D KDM5A KDM5C CHD5

1.17e-0795466PS50016
DomainJmjC

KDM5B KDM5D KDM5A KDM5C

3.30e-0724464PF02373
DomainJMJC

KDM5B KDM5D KDM5A KDM5C

1.10e-0632464PS51184
DomainJmjC_dom

KDM5B KDM5D KDM5A KDM5C

1.10e-0632464IPR003347
Domain-

KDM5B CHD4 RIMS1 KDM5D PHF20L1 RNF139 KDM5A KDM5C CHD5

1.24e-064494693.30.40.10
DomainJmjC

KDM5B KDM5D KDM5A KDM5C

1.25e-0633464SM00558
DomainChromo/shadow_dom

SMARCC1 CHD2 CHD4 CHD5

1.25e-0633464IPR000953
DomainCHROMO

SMARCC1 CHD2 CHD4 CHD5

1.25e-0633464SM00298
DomainZnf_RING/FYVE/PHD

KDM5B CHD4 RIMS1 KDM5D PHF20L1 RNF139 KDM5A KDM5C CHD5

1.49e-06459469IPR013083
DomainCHDCT2

CHD4 CHD5

1.78e-053462PF08074
DomainCHDNT

CHD4 CHD5

1.78e-053462PF08073
DomainDUF1086

CHD4 CHD5

1.78e-053462IPR009462
DomainDUF1087

CHD4 CHD5

1.78e-053462IPR009463
DomainCHD_N

CHD4 CHD5

1.78e-053462IPR012958
DomainCHD_C2

CHD4 CHD5

1.78e-053462IPR012957
DomainDUF1087

CHD4 CHD5

1.78e-053462PF06465
DomainDUF1086

CHD4 CHD5

1.78e-053462PF06461
DomainDUF1087

CHD4 CHD5

1.78e-053462SM01147
DomainDUF1086

CHD4 CHD5

1.78e-053462SM01146
DomainChromo_domain

CHD2 CHD4 CHD5

2.73e-0524463IPR023780
DomainChromo

CHD2 CHD4 CHD5

3.49e-0526463PF00385
DomainCHROMO_1

CHD2 CHD4 CHD5

4.39e-0528463PS00598
DomainCHROMO_2

CHD2 CHD4 CHD5

4.39e-0528463PS50013
DomainSNF2_N

CHD2 CHD4 CHD5

6.60e-0532463IPR000330
DomainChromodomain-like

CHD2 CHD4 CHD5

6.60e-0532463IPR016197
DomainSNF2_N

CHD2 CHD4 CHD5

6.60e-0532463PF00176
DomainDNA/RNA_helicase_DEAH_CS

CHD2 CHD4 CHD5

8.66e-0535463IPR002464
DomainDEAH_ATP_HELICASE

CHD2 CHD4 CHD5

1.11e-0438463PS00690
DomainHelicase_C

CHD2 CHD4 CHD5

2.32e-03107463PF00271
DomainHELICc

CHD2 CHD4 CHD5

2.32e-03107463SM00490
DomainHelicase_C

CHD2 CHD4 CHD5

2.38e-03108463IPR001650
DomainHELICASE_CTER

CHD2 CHD4 CHD5

2.45e-03109463PS51194
DomainHELICASE_ATP_BIND_1

CHD2 CHD4 CHD5

2.45e-03109463PS51192
DomainDEXDc

CHD2 CHD4 CHD5

2.45e-03109463SM00487
DomainHelicase_ATP-bd

CHD2 CHD4 CHD5

2.51e-03110463IPR014001
Domain-

GBE1 KLB

3.35e-03354623.20.20.80
DomainSulfotransferase_dom

NDST1 DSEL

3.54e-0336462IPR000863
DomainSulfotransfer_1

NDST1 DSEL

3.54e-0336462PF00685
DomainGlyco_hydro_catalytic_dom

GBE1 KLB

3.94e-0338462IPR013781
PathwayREACTOME_CHROMATIN_MODIFYING_ENZYMES

SMARCC1 KDM5B CHD4 KDM5D PRMT7 KDM5A KDM5C

3.03e-07175377MM14941
PathwayREACTOME_HDMS_DEMETHYLATE_HISTONES

KDM5B KDM5D KDM5A KDM5C

9.10e-0729374MM14934
PathwayREACTOME_CHROMATIN_MODIFYING_ENZYMES

SMARCC1 KDM5B CHD4 KDM5D PRMT7 KDM5A KDM5C

5.78e-06272377M29619
PathwayREACTOME_HDMS_DEMETHYLATE_HISTONES

KDM5B KDM5D KDM5A KDM5C

8.48e-0650374M27232
PathwayREACTOME_GLYCOSAMINOGLYCAN_METABOLISM

NDST1 FMOD HAS3 DSEL

2.92e-04123374MM14623
PathwayREACTOME_GLYCOSAMINOGLYCAN_METABOLISM

NDST1 FMOD HAS3 DSEL

3.20e-04126374M695
PathwayREACTOME_METABOLISM_OF_CARBOHYDRATES

GBE1 NDST1 FMOD HAS3 DSEL

6.67e-04271375MM15406
Pubmed

Novel JARID1C/SMCX mutations in patients with X-linked mental retardation.

KDM5B KDM5D KDM5A KDM5C

2.68e-12446416541399
Pubmed

Multiplexed barcoded CRISPR-Cas9 screening enabled by CombiGEM.

KDM5B KDM5D PRMT7 KDM5A KDM5C

7.47e-103346526864203
Pubmed

The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6→ Tbr2→ Tbr1.

SMARCC1 KDM5B CHD2 CHD4 KDM5D KDM5A KDM5C

1.54e-0915746730186101
Pubmed

Dynamic patterns of histone H3 lysine 4 methyltransferases and demethylases during mouse preimplantation development.

KDM5B KDM5D KDM5A KDM5C

1.90e-091346424619213
Pubmed

Histone demethylase KDM5 regulates cardiomyocyte maturation by promoting fatty acid oxidation, oxidative phosphorylation, and myofibrillar organization.

KDM5B KDM5A KDM5C

2.17e-09346338230606
Pubmed

Characterization of a Linked Jumonji Domain of the KDM5/JARID1 Family of Histone H3 Lysine 4 Demethylases.

KDM5B KDM5A KDM5C

2.17e-09346326645689
Pubmed

The X-linked mental retardation gene SMCX/JARID1C defines a family of histone H3 lysine 4 demethylases.

KDM5B KDM5D KDM5C

8.65e-09446317320160
Pubmed

Histone lysine demethylase JARID1a activates CLOCK-BMAL1 and influences the circadian clock.

KDM5B KDM5A KDM5C

4.32e-08646321960634
Pubmed

Single-cell profiling of epigenetic modifiers identifies PRDM14 as an inducer of cell fate in the mammalian embryo.

KDM5B PRMT7 KDM5A KDM5C

3.50e-074446424183668
Pubmed

Identification of Jmjd3 as an Essential Epigenetic Regulator of Hox Gene Temporal Collinear Activation for Body Axial Patterning in Mice.

KDM5B KDM5D KDM5A KDM5C

5.43e-074946434368113
Pubmed

Evolutionary strata on the mouse X chromosome correspond to strata on the human X chromosome.

UBA1 KDM5D KDM5C

9.74e-071546314762062
Pubmed

New nomenclature for chromatin-modifying enzymes.

KDM5B KDM5D KDM5A KDM5C

1.00e-065746418022353
Pubmed

Mutations of histone demethylase genes encoded by X and Y chromosomes, Kdm5c and Kdm5d, lead to noncompaction cardiomyopathy in mice.

KDM5D KDM5C

1.71e-06246232081420
Pubmed

KDM5A and KDM5B histone-demethylases contribute to HU-induced replication stress response and tolerance.

KDM5B KDM5A

1.71e-06246234184733
Pubmed

Drawing a line between histone demethylase KDM5A and KDM5B: their roles in development and tumorigenesis.

KDM5B KDM5A

1.71e-06246236509829
Pubmed

Fibromodulin Interacts with Collagen Cross-linking Sites and Activates Lysyl Oxidase.

FMOD LOX

1.71e-06246226893379
Pubmed

Analysis of mutation rates in the SMCY/SMCX genes shows that mammalian evolution is male driven.

KDM5D KDM5C

1.71e-0624629060413
Pubmed

Alcohol-associated fibrosis in females is mediated by female-specific activation of lysine demethylases KDM5B and KDM5C.

KDM5B KDM5C

1.71e-06246235468265
Pubmed

Mouse H-Y encoding Smcy gene and its X chromosomal homolog Smcx.

KDM5D KDM5C

1.71e-06246210441747
Pubmed

Inefficient purifying selection: the mammalian Y chromosome in the rodent genus Mus.

KDM5D KDM5C

1.71e-06246216416087
Pubmed

KDM5 Histone Demethylase Activity Links Cellular Transcriptomic Heterogeneity to Therapeutic Resistance.

KDM5B KDM5A

1.71e-06246230472020
Pubmed

KDM5 lysine demethylases are involved in maintenance of 3'UTR length.

KDM5B KDM5A

1.71e-06246228138513
Pubmed

A mouse Y chromosome gene encoded by a region essential for spermatogenesis and expression of male-specific minor histocompatibility antigens.

KDM5D KDM5C

1.71e-0624627524912
Pubmed

Sex differences in sex chromosome gene expression in mouse brain.

UBA1 KDM5D KDM5C

1.74e-061846312023983
Pubmed

The histone demethylase Jarid1b ensures faithful mouse development by protecting developmental genes from aberrant H3K4me3.

KDM5B KDM5A KDM5C

2.43e-062046323637629
Pubmed

Broad histone H3K4me3 domains in mouse oocytes modulate maternal-to-zygotic transition.

KDM5B KDM5A KDM5C

2.83e-062146327626377
Pubmed

Structural analysis of human KDM5B guides histone demethylase inhibitor development.

KDM5B KDM5C

5.13e-06346227214403
Pubmed

Identification of a mouse male-specific transplantation antigen, H-Y.

KDM5D KDM5C

5.13e-0634627544442
Pubmed

Re-expression of the retinoblastoma-binding protein 2-homolog 1 reveals tumor-suppressive functions in highly metastatic melanoma cells.

KDM5B KDM5A

5.13e-06346216645588
Pubmed

RBP2 belongs to a family of demethylases, specific for tri-and dimethylated lysine 4 on histone 3.

KDM5A KDM5C

5.13e-06346217320161
Pubmed

KDM5 family of demethylases promotes CD44-mediated chemoresistance in pancreatic adenocarcinomas.

KDM5A KDM5C

5.13e-06346237880235
Pubmed

Characterization of the CHD family of proteins.

CHD2 CHD4

1.03e-0544629326634
Pubmed

X- and Y-Linked Chromatin-Modifying Genes as Regulators of Sex-Specific Cancer Incidence and Prognosis.

KDM5D KDM5C

1.03e-05446232732223
Pubmed

A novel X gene with a widely transcribed Y-linked homologue escapes X-inactivation in mouse and human.

KDM5D KDM5C

1.03e-0544627951230
Pubmed

H3K4 demethylation by Jarid1a and Jarid1b contributes to retinoblastoma-mediated gene silencing during cellular senescence.

KDM5B KDM5A

1.03e-05446222615382
Pubmed

Molecular analysis of an isoYq chromosome in a sterile male mouse.

UBA1 KDM5D

1.03e-0544628678984
Pubmed

MicroRNAs regulate KDM5 histone demethylases in breast cancer cells.

KDM5B KDM5C

1.71e-05546226621457
Pubmed

An ikaros-containing chromatin-remodeling complex in adult-type erythroid cells.

SMARCC1 CHD4

2.56e-05646211003653
Pubmed

DNA-binding properties of ARID family proteins.

KDM5B KDM5A

3.58e-05746215640446
Pubmed

Potent and Selective KDM5 Inhibitor Stops Cellular Demethylation of H3K4me3 at Transcription Start Sites and Proliferation of MM1S Myeloma Cells.

KDM5B KDM5C

3.58e-05746228262558
Pubmed

The polycomb group protein L3mbtl2 assembles an atypical PRC1-family complex that is essential in pluripotent stem cells and early development.

SMARCC1 CHD4 KDM5C

4.31e-055146322770845
Pubmed

Jade-1S phosphorylation induced by CK1α contributes to cell cycle progression.

CHD4 PHF20L1 KDM5A

5.71e-055646326919559
Pubmed

The Brd4 extraterminal domain confers transcription activation independent of pTEFb by recruiting multiple proteins, including NSD3.

SMARCC1 CHD4 CHD5

6.03e-055746321555454
Pubmed

Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.

SMARCC1 KDM5B KDM5D PHF20L1 KDM5A KDM5C ZDHHC16

8.66e-0580846720412781
Pubmed

Ikaros DNA-binding proteins direct formation of chromatin remodeling complexes in lymphocytes.

SMARCC1 CHD4

9.34e-051146210204490
Pubmed

Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.

SMARCC1 GBE1 CHD2 LMF1 CHD4 MAN1A2 H6PD LOX CDS2

1.02e-04145146930550785
Pubmed

Lymph Node Mesenchymal and Endothelial Stromal Cells Cooperate via the RANK-RANKL Cytokine Axis to Shape the Sinusoidal Macrophage Niche.

SIGLEC1 CLCA1

1.12e-041246231201093
Pubmed

Sex differences in structure and expression of the sex chromosome genes CHD1Z and CHD1W in zebra finches.

KDM5D KDM5C

1.32e-041346214660691
Pubmed

Screen identifies bromodomain protein ZMYND8 in chromatin recognition of transcription-associated DNA damage that promotes homologous recombination.

CHD4 PHF20L1 KDM5A

1.37e-047546325593309
Pubmed

The in vivo Interaction Landscape of Histones H3.1 and H3.3.

SMARCC1 CHD2 CHD4 PHF20L1 KDM5A CHD5

1.44e-0460846636089195
Pubmed

DLX1 and the NuRD complex cooperate in enhancer decommissioning and transcriptional repression.

CHD4 CHD5

1.78e-041546235695185
Pubmed

TIF1beta/KAP-1 is a coactivator of the orphan nuclear receptor NGFI-B/Nur77.

SMARCC1 CHD4

1.78e-041546219321449
Pubmed

The chromatin remodeling factor CHD5 is a transcriptional repressor of WEE1.

CHD4 CHD5

1.78e-041546225247294
Pubmed

Evidence of Xist RNA-independent initiation of mouse imprinted X-chromosome inactivation.

UBA1 KDM5C

2.30e-041746219571810
Pubmed

Transcription precedes loss of Xist coating and depletion of H3K27me3 during X-chromosome reprogramming in the mouse inner cell mass.

UBA1 KDM5C

2.30e-041746221471155
Pubmed

A Functional Switch of NuRD Chromatin Remodeling Complex Subunits Regulates Mouse Cortical Development.

CHD4 CHD5

2.30e-041746227806305
Pubmed

An expanded Oct4 interaction network: implications for stem cell biology, development, and disease.

SMARCC1 CHD4 CHD5

2.42e-049146320362542
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

USP25 NDST1 KDM5B MRPL38 CHD4 MAN1A2 KDM5A USP32

2.54e-04128546835914814
Pubmed

Mesenchymal-epithelial interaction regulates gastrointestinal tract development in mouse embryos.

CLCA1 LOX

2.58e-041846235830795
Pubmed

Heterogeneous nuclear ribonucleoprotein C1/C2, MeCP1, and SWI/SNF form a chromatin remodeling complex at the beta-globin locus control region.

SMARCC1 CHD4

2.58e-041846216217013
Pubmed

TRIM28 interacts with EZH2 and SWI/SNF to activate genes that promote mammosphere formation.

SMARCC1 CHD4

2.58e-041846228068325
Pubmed

Binding specificity of Toll-like receptor cytoplasmic domains.

PTPN6 TLR8

2.88e-041946216482509
Pubmed

Purification and Transcriptomic Analysis of Mouse Fetal Leydig Cells Reveals Candidate Genes for Specification of Gonadal Steroidogenic Cells.

ADAMTS16 CLCA1

2.88e-041946225855264
Pubmed

NuRD subunit CHD4 regulates super-enhancer accessibility in rhabdomyosarcoma and represents a general tumor dependency.

SMARCC1 CHD4 CHD5

3.49e-0410346332744500
Pubmed

Failure of extra-embryonic progenitor maintenance in the absence of dosage compensation.

UBA1 KDM5C

4.25e-042346222573614
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

SMARCC1 CHD4 UBA1 RIMS1 KDM5A KDM5C

5.23e-0477446615302935
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

SMARCC1 CHD2 DENND4A CHD4 RIMS1 PHF20L1 KDM5A CHD5

5.48e-04144246835575683
Pubmed

Chromatin regulation by BAF170 controls cerebral cortical size and thickness.

SMARCC1 PROM1

6.33e-042846223643363
Pubmed

RNF138 inhibits late inflammatory gene transcription through degradation of SMARCC1 of the SWI/SNF complex.

SMARCC1 CHD4

6.79e-042946236800290
Pubmed

The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation.

SMARCC1 MRPL38 CHD2 CHD4 UBA1 KDM5A CHD5

7.47e-04115346729845934
Pubmed

Interaction of Sox2 with RNA binding proteins in mouse embryonic stem cells.

SMARCC1 KDM5B CHD4

7.68e-0413546331077711
Pubmed

Investigation of genetic susceptibility factors for human longevity - a targeted nonsynonymous SNP study.

GBE1 SIGLEC1 H6PD KLB

7.80e-0431346420800603
Pubmed

Protein interactome mining defines melatonin MT1 receptors as integral component of presynaptic protein complexes of neurons.

CHD4 UBA1 USP32 ZDHHC16

8.66e-0432246426514267
Pubmed

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.

SMARCC1 MRPL38 CHD4 PHF20L1 KDM5A KDM5C

8.89e-0485746625609649
Pubmed

Discovery and Characterization of ZUFSP/ZUP1, a Distinct Deubiquitinase Class Important for Genome Stability.

USP25 CHD4 USP32

9.83e-0414746329576527
Pubmed

Identification of the BRD1 interaction network and its impact on mental disorder risk.

CHD4 CHD5

9.90e-043546227142060
Pubmed

ZMYM3 regulates BRCA1 localization at damaged chromatin to promote DNA repair.

SMARCC1 CHD4 PHF20L1

1.04e-0315046328242625
Pubmed

A cryptic Tudor domain links BRWD2/PHIP to COMPASS-mediated histone H3K4 methylation.

CHD4 CHD5

1.05e-033646229089422
Pubmed

A Y2H-seq approach defines the human protein methyltransferase interactome.

GBE1 MRPL38 PRMT7 PHF20L1

1.08e-0334246423455924
Pubmed

LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow.

GBE1 PTPN6 CHD4 UBA1

1.11e-0334446430333137
Pubmed

Analysis of the SWI/SNF chromatin-remodeling complex during early heart development and BAF250a repression cardiac gene transcription during P19 cell differentiation.

SMARCC1 CHD4

1.11e-033746224335282
Pubmed

Cross-linking mass spectrometry reveals the structural topology of peripheral NuRD subunits relative to the core complex.

CHD4 CHD5

1.17e-033846233283408
Pubmed

Identification and Functional Characterization of a Novel Androgen Receptor Coregulator, EAP1.

SMARCC1 CHD4

1.29e-034046234585037
InteractionMBD2 interactions

SMARCC1 KDM5B CHD4 PHF20L1 KDM5C CHD5

1.49e-06161456int:MBD2
Cytoband16q22.1

SLC9A5 HAS3 PRMT7

1.88e-0411046316q22.1
CytobandEnsembl 112 genes in cytogenetic band chr16q22

SLC9A5 HAS3 PRMT7

8.34e-04183463chr16q22
Cytoband12p13

PTPN6 CHD4

1.90e-036446212p13
GeneFamilyPHD finger proteins

KDM5B CHD4 KDM5D PHF20L1 KDM5A KDM5C CHD5

2.88e-109034788
GeneFamilyAT-rich interaction domain containing

KDM5B KDM5D KDM5A KDM5C

1.40e-0815344418
GeneFamilyPHD finger proteins|Lysine demethylases

KDM5B KDM5D KDM5A KDM5C

1.08e-0724344485
GeneFamilyPHD finger proteins|NuRD complex

CHD4 CHD5

2.24e-04123421305
GeneFamilyUbiquitin specific peptidases

USP25 USP32

4.96e-0356342366
ToppCellfacs-Marrow-B-cells-3m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS16 RIMS1 FMOD KLB

1.22e-051374644dcb15de821439011df1bb0bbd7682d674bd725d
ToppCellfacs-Marrow-B-cells-3m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS16 RIMS1 FMOD KLB

1.22e-05137464c05ceeb7b483324604cb3f647d2da2b3786071b1
ToppCelldroplet-Thymus-nan-24m-Lymphocytic-Double_negative_thymocyte,_DN3_(Cd8-,_Cd4-),_some_express_pre_TCR_alpha|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DENND4A LMF1 KDM5D OSBPL5

3.62e-05181464d8d11ef83c4b8b6a6f5c8728e03059e45a8ad264
ToppCellfacs-Pancreas-Exocrine-18m-Mesenchymal|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM47 FMOD LOX LRRC17

3.62e-05181464269b39ac65790061d54eab47a8eeb024403f0348
ToppCellfacs-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM47 FMOD LOX LRRC17

3.62e-05181464cd4f744b6b64ba6c22ec07afd1d3058a2546909d
ToppCelldroplet-Thymus-nan-24m-Lymphocytic-DN3_thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DENND4A LMF1 KDM5D OSBPL5

3.62e-05181464e2d03115a87f45a7ddd3ade6b9ac3843639bd41a
ToppCellfacs-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM47 FMOD LOX LRRC17

3.62e-05181464c8395ae872aa80b3ae1ab7c53e57b3ca15aeb0e2
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_adventitial_fibro_(10)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

ADAMTS16 FMOD LOX LRRC17

4.38e-051904644f775ee24b14733f06ae40b45f2dc1a0f0df0705
ToppCelldroplet-Pancreas-Exocrine-18m-Endothelial-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR4 TMEM47 SLC9A5 CLCA1

4.56e-05192464a42aed9e563f5f4af029b8804c104f11ad227a8f
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_adventitial_fibro_(10)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

ADAMTS16 FMOD LOX LRRC17

4.65e-05193464adc9fc94f9ec686a417d08c0b8b7b7ab687afec0
ToppCelltumor_Lung-Fibroblasts-Myofibroblasts|tumor_Lung / Location, Cell class and cell subclass

ADAMTS16 FMOD LOX LRRC17

5.14e-0519846431f9181dab689aabe9c6182c2ef7de65ba3f0ff6
ToppCell356C-Fibroblasts-Fibroblast-F|356C / Donor, Lineage, Cell class and subclass (all cells)

ADAMTS16 FMOD LOX LRRC17

5.24e-0519946459fe5f3c6338e019a149ab135acf9cc5657298bf
ToppCellwk_15-18-Mesenchymal-Fibroblast-Adventitial_fibro|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

ADAMTS16 FMOD LOX LRRC17

5.24e-051994648de6d7b2067b22cb9b5f01aa56a3803aebc4406d
ToppCell356C-Fibroblasts-Fibroblast-F-|356C / Donor, Lineage, Cell class and subclass (all cells)

ADAMTS16 FMOD LOX LRRC17

5.24e-05199464136f24597ddca5cf2175120975c94782a3232ec6
ToppCellwk_20-22-Mesenchymal-Fibroblast-Adventitial_fibro|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

ADAMTS16 FMOD DSEL LOX

5.24e-05199464ab0589c068c24aa989bdca083504fbad0c15221d
ToppCellLung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Fibroblasts-4|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

FMOD DSEL LOX LRRC17

5.34e-052004648256511b099c3eab8e33194f90c9ff354e7cfe8e
ToppCellBiopsy_Control_(H.)-Mesenchymal-Fibroblasts|Biopsy_Control_(H.) / Sample group, Lineage and Cell type

ADAMTS16 FMOD LOX LRRC17

5.34e-052004648d75ce89393df452defacf2ec9a5bd4b7708afbb
ToppCellBiopsy_IPF-Mesenchymal-PLIN2+_Fibroblasts|Biopsy_IPF / Sample group, Lineage and Cell type

ADAMTS16 FMOD LOX LRRC17

5.34e-052004642c5626ea8fb4b702d4560117e53edf6cfcf1971e
ToppCellLung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Fibroblasts-4-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

FMOD DSEL LOX LRRC17

5.34e-052004644dbe21cb63569f28c7017cda065ea5ee00d7254e
ToppCellParenchyma_COVID-19-Stromal-TX-Fibroblasts-4|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

FMOD DSEL LOX LRRC17

5.34e-05200464bde938e5a18844fb8cc1d1be5a086809f7e2b97d
ToppCellParenchymal-10x5prime-Stromal-Fibroblastic-Fibro_myofibroblast|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ADAMTS16 FMOD LOX LRRC17

5.34e-0520046454806080b5e97859ee6a4a9b4f19e22021c218f5
ToppCellBiopsy_IPF-Mesenchymal-HAS1_High_Fibroblasts|Biopsy_IPF / Sample group, Lineage and Cell type

ADAMTS16 FMOD LOX LRRC17

5.34e-05200464d02e256b5d65a5c982ba5696bc7e077281ca3e24
ToppCell367C-Fibroblasts|367C / Donor, Lineage, Cell class and subclass (all cells)

TMEM47 FMOD LOX LRRC17

5.34e-05200464c5aaa20c59b9f11b8abdf5de9e3fc54f4e6e39f7
ToppCell18-Airway-Mesenchymal|Airway / Age, Tissue, Lineage and Cell class

TMEM47 FMOD LOX LRRC17

5.34e-05200464aca1e8def8ed6ae5749402d0288ad90656213de1
ToppCellprimary_visual_cortex-Non-neuronal-macrophage-Macrophage-PVM_Mrc1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PTPN6 SIGLEC1 TLR8

3.27e-041304633a0846b74ba34bd0e2a05b4f1f39f3940df93780
ToppCell10x3'2.3-week_12-13-Hematopoietic-HSC/MPP_and_pro-MPP_myeloid|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

PROM1 KDM5B RIMS1

4.06e-04140463eb1d22f5f5dbf60b6485464baec4be9b3060f65c
ToppCellIIH-CD4-CD8_1|IIH / Condition, Cell_class and T cell subcluster

USP25 DCAF15 H6PD

4.50e-04145463296b6b0eea3233d76742ea35252b2f54d4c27ab6
ToppCellfrontal_cortex-Non-neuronal-macrophage-Macrophage-PVM_Mrc1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PTPN6 SIGLEC1 TLR8

4.77e-04148463d3ea907f8f408e9bb97ed223a3089e403e35f911
ToppCellTCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Ductal_and_Lobular_Carcinoma-6|TCGA-Breast / Sample_Type by Project: Shred V9

ADAMTS16 LOX LRRC17

4.87e-041494633904f8ce9078de238600ceceee0116af52256a1c
ToppCell3'-Parenchyma_lung-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SMARCC1 HAS3 KDM5C

5.26e-0415346392a5307b8e4dcf9ee42134b4c0645f9d488df61a
ToppCellControl-Endothelial-Epi-like-Alv_Cap|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

RIMS1 HAS3 PRMT7

5.67e-041574632c369660c752c0fb3bd798a561d3359e2f9aa983
ToppCellTCGA-Endometrium-Primary_Tumor-Endometrial_Adenocarcinoma-Serous_adenocarcinoma-5|TCGA-Endometrium / Sample_Type by Project: Shred V9

ADAMTS16 PRSS50 CHD4

5.67e-0415746359450e9f580555091b159fbbe0a0756e51bcd9ad
ToppCellControl-Endothelial-Epi-like|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

RIMS1 HAS3 PRMT7

5.67e-041574634d02c50d5d1b892ea241e98724386d8a5a156a46
ToppCellfacs-Lung-EPCAM-3m-Myeloid-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPN6 SIGLEC1 TLR8

5.77e-04158463ef5feb48161c339c7b71c576bdda61479d29dfac
ToppCellfacs-Lung-EPCAM-3m-Myeloid-Classical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPN6 SIGLEC1 TLR8

5.77e-04158463c6e64b9b3342e37d54baadae8fb7dfb5d246e4cf
ToppCellE18.5-samps-Mesenchymal-Matrix_fibroblast-FB-1|E18.5-samps / Age Group, Lineage, Cell class and subclass

H6PD LOX LRRC17

5.88e-04159463b4bc888e978b1b577721b891b0af6ba9a1607044
ToppCellfacs-Brain_Myeloid-Cerebellum-3m-Myeloid-macrophage|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SIGLEC1 FMOD TLR8

5.88e-04159463323cb4a2416d2e6bff0a3f225d2edeae9ab7dc76
ToppCellCV-Mild-4|Mild / Virus stimulation, Condition and Cluster

GBE1 KDM5D HAS3

5.99e-041604632e24f8de5086b086863d3bf4d9afbd9bc93f4d5e
ToppCelldroplet-Liver-HEPATOCYTES-1m-Epithelial-Hepatocyte_(Pericentral)|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GBE1 H6PD ELOVL6

5.99e-04160463c42bcc6c7d113f0db43febb088b75ca4ac7cb7a3
ToppCellfacs-Lung-Endomucin_-18m-Myeloid-Neutrophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPN6 DENND4A USP32

6.10e-04161463e227f7b711475624cf80e77f235b1783d88d57b4
ToppCellfacs-Lung-Endomucin_-18m-Myeloid-neutrophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPN6 DENND4A USP32

6.10e-041614638280a029026c272cae9649b27575831b0dd4e242
ToppCellClub_cells-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

PROM1 RIMS1 LOX

6.66e-04166463a440aa338aa0c6cd0b5800dfa7e83f8ca16fce1a
ToppCellTCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-5|TCGA-Ovary / Sample_Type by Project: Shred V9

SMARCC1 CHD2 CHD4

6.66e-0416646332d2eaf8a5d03881bf74d680825af2d5110b082d
ToppCellfacs-SCAT-Fat-3m-Myeloid-myeloid_cell|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPN6 SIGLEC1 TLR8

6.66e-041664638395c74db8e4e54af97a3f2b75cb75171140ec31
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Degenerative_Podocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MRPL38 TLR8 LOX

6.66e-04166463dc443a3327dc8f9a0d808c3c6e06b0834d45f5c2
ToppCellfacs-SCAT-Fat-3m-Myeloid|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPN6 SIGLEC1 TLR8

6.66e-0416646376807edc5620514b53a14be354b84c54c112b8f9
ToppCellfacs-SCAT-Fat-3m-Myeloid-nan|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPN6 SIGLEC1 TLR8

6.66e-04166463645b842b94b8d2f4b26c2623f8589f56bd782c26
ToppCellTCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Squamous_Cell_Carcinoma-4|TCGA-Lung / Sample_Type by Project: Shred V9

ADAMTS16 FMOD LOX

6.90e-04168463aefea14b8b1c1b6a05f827effd22ba15274fddc9
ToppCellfacs-Heart-RV-3m-Myeloid-monocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPN6 SIGLEC1 TLR8

6.90e-04168463a405f0de70293f68b4e000c1fc8a9ad33d56539a
ToppCelldroplet-Liver-HEPATOCYTES-1m-Epithelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GBE1 H6PD ELOVL6

6.90e-04168463b98af4043dfa5dfa4413e482879fad88de484675
ToppCellfacs-Heart-RV-3m-Myeloid-monocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPN6 SIGLEC1 TLR8

6.90e-041684638ee57814c7e9d45444f48b6b269c4d535bc4d5e1
ToppCellfacs-Heart-RV-3m-Myeloid|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPN6 SIGLEC1 TLR8

6.90e-04168463c1a5f4f4d32a1f8583048db709a7037cc9357ad8
ToppCelldroplet-Liver-HEPATOCYTES-1m-Epithelial-hepatocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GBE1 H6PD ELOVL6

6.90e-04168463073b53d4cee6bc8c5c6fce51cf6cd9c316478f69
ToppCelldroplet-Liver-HEPATOCYTES|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GBE1 H6PD ELOVL6

7.02e-04169463f195467438c589f87224bde7da720dea072d110c
ToppCelldroplet-Liver-HEPATOCYTES-1m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GBE1 H6PD ELOVL6

7.02e-041694637785cab967a33560830c394c918d6ce625103858
ToppCellfacs-Lung-24m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l5|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CHD2 RIMS1 PKDREJ

7.02e-04169463a388e53deac861a185c31e9cceddae7bcb344700
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PROM1 FMOD RNF139

7.02e-041694638f397cf4f9fd7c6fa88d01a95289ce2a6bc6938d
ToppCellfacs-Lung-nan-3m-Endothelial-vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRSS50 NDST1 CLCA1

7.14e-0417046367d7e1da3ebd2d14cb2e67799e94d655027ed5c4
ToppCellfacs-Lung-nan-3m-Endothelial-Vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRSS50 NDST1 CLCA1

7.14e-041704638e1f757ed62218c0fb6525f49d142dd2cd29acf9
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PROM1 FMOD RNF139

7.26e-04171463effcc4b6d26eafc2ca6fa08b6fee2689eff48f0f
ToppCell367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)

MRPL38 SIGLEC1 LOX

7.39e-04172463da959c1abadafd79b7a0088a25eb8ef8efa3a0c2
ToppCellfacs-Heart-LA-3m-Myeloid|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPN6 SIGLEC1 TLR8

7.64e-0417446330c083fe4711735e83dccfd00fcd746ae673d353
ToppCellfacs-Heart-LV-3m-Myeloid-monocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPN6 SIGLEC1 TLR8

7.64e-04174463dc8a238ec1d954bec0f8eb67c04a61734c96f5b5
ToppCellfacs-Heart-LV-3m-Myeloid-monocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPN6 SIGLEC1 TLR8

7.64e-0417446354166a0faf748cccb6406c2c268e1e6e21caf6d0
ToppCellfacs-Heart-LA-3m-Myeloid-monocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPN6 SIGLEC1 TLR8

7.64e-0417446346d19c1144fff19be682b7ba59d4c3e014f79e15
ToppCellfacs-Heart-LA-3m-Myeloid-monocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPN6 SIGLEC1 TLR8

7.64e-041744631802a52552256d1e25d8b328ba62dcfe41671900
ToppCellfacs-Heart-LV-3m-Myeloid|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPN6 SIGLEC1 TLR8

7.76e-041754635d106ef542b97f97aeb19179e3f72963ead1e82a
ToppCelldroplet-Liver-HEPATOCYTES-1m-Epithelial-Hepatocyte_(Periportal)|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GBE1 H6PD ELOVL6

7.76e-041754635c38d4b6c03473d841e6203a7efaa6dcb2d59386
ToppCell(06)_Krt4/13+-(2)_48hpi|(06)_Krt4/13+ / shred by cell type and Timepoint

PROM1 CLCA1

7.78e-04404621e42cd186ee06ac9345e16ede649a72c15bdf2f8
ToppCellE16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GPR4 TMEM47 CLCA1

7.89e-0417646377516048aefbe1f48e825052756df0c310c1c486
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex_prolif|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DCAF15 RIMS1 LOX

7.89e-041764638eb91dcf55d4e3e28a72d447181bf6d2ad891fc6
ToppCellE16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GPR4 TMEM47 CLCA1

7.89e-0417646396779273b94345250cf53ba671203345b43d9e00
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Degenerative_Vascular_Smooth_Muscle_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TMEM47 FMOD CHD5

8.16e-04178463e5e5f5b4a27e120a1076b1cb250fa25d0c336956
ToppCell(5)_Glands_mucous|World / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)

PROM1 FMOD KDM5A

8.16e-04178463f0f19b0d78f2cc5df4d4c321a953a6e447d5114a
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Degenerative_Vascular_Smooth_Muscle_Cell-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TMEM47 FMOD CHD5

8.16e-04178463c661246269ce26c4fc62e12f86c5f90a2dcfdce0
ToppCellnormal-na-Lymphocytic_T-CD4-positive,_alpha-beta_T_cell-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

CHD2 RIMS1 KDM5D

8.16e-04178463fa3585383a1e7da460c88a802aaa81246d681b6b
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Mucinous_Colon_Adenocarcinoma-10|TCGA-Colorectal / Sample_Type by Project: Shred V9

ADAMTS16 TLR8 LOX

8.29e-04179463cc079ba015326dccde955c5eafa3e4a2e40de192
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

H6PD LOX LRRC17

8.29e-04179463948c2a01ec7a626c68281e6e796a9f0527a88591
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TMEM47 LOX ZDHHC16

8.29e-04179463ce3ca7f3a5864e62307aa744a3173f350a90df28
ToppCellASK440-Immune-NK_cell|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq

ELOVL6 PKDREJ OSBPL5

8.42e-04180463340e750356d23fe9af0e8f298f8a273ff426052f
ToppCellP15-Mesenchymal-mesenchymal_fibroblast-mesenchymal_alveolar_niche_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

FMOD LOX LRRC17

8.70e-04182463e9fcae9d03a6faf85b91882c5da699037bc61aeb
ToppCellfacs-Liver-Hepatocytes-24m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GBE1 H6PD KLB

8.84e-04183463d0721c6aa426953a520d40e976b6e65aa7ca65e8
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Endothelial-leukocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DENND4A CLCA1 KDM5D

8.84e-04183463919c9861073d12fd12aecd7469b1478b13838c43
ToppCell5'-Adult-LargeIntestine-Mesenchymal-myocytic-myofibroblast|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TMEM47 DSEL LRRC17

8.84e-04183463af8d86f15a549064530d94bd47081daf59d58ecd
ToppCellnormal-na-Lymphocytic_T-T8_naive-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

CHD2 KDM5D DSEL

8.98e-041844634a81190b36d197736663e6177d3b76c1cb6282d6
ToppCellBrain_organoid-organoid_Kanton_Nature|Brain_organoid / Sample Type, Dataset, Time_group, and Cell type.

SMARCC1 UBA1 MAN1A2

9.12e-04185463857c7ca8493e91ef1d0078ddafd6082020f9b169
ToppCellLPS_only|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GBE1 CHD2 DENND4A

9.12e-04185463a72ccb147ca505880e2da8f6a70b9d570464a691
ToppCell390C-Fibroblasts-Fibroblast-F|390C / Donor, Lineage, Cell class and subclass (all cells)

ADAMTS16 LOX LRRC17

9.12e-041854632c1f14f77faeee2acb388d997c5a27a7fef79be1
ToppCell390C-Fibroblasts-Fibroblast-F-|390C / Donor, Lineage, Cell class and subclass (all cells)

ADAMTS16 LOX LRRC17

9.12e-0418546337db8e0b1f59274227f6fc2362167eb44bd080ef
ToppCell368C-Myeloid-Macrophage-FABP4+_Macrophage_3|368C / Donor, Lineage, Cell class and subclass (all cells)

PTPN6 SIGLEC1 TLR8

9.26e-04186463ddfadd43efeac3b3e6b7062590cc2b8f2f2db2ab
ToppCellSubstantia_nigra-Neuronal-Inhibitory|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

RIMS1 SLC9A5 CHD5

9.26e-041864639d3efe2a4feea2bc205a7e45b9b9f9ed9b3609ce
ToppCellTCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Ductal_Carcinoma-6|TCGA-Breast / Sample_Type by Project: Shred V9

ADAMTS16 LOX LRRC17

9.40e-04187463a96495803ba13fcfadd1d83b3cf5774f3fed0a20
ToppCellRA-11._Adipocyte|World / Chamber and Cluster_Paper

GBE1 ELOVL6 KLB

9.55e-041884634dac9d636e5cad4cda540b93d4bfed6b5732c880
ToppCellE16.5-samps-Mesenchymal|E16.5-samps / Age Group, Lineage, Cell class and subclass

H6PD LOX LRRC17

9.55e-041884633f0f662be684e3a4c6652e636cc135a39a1d2790
ToppCell10x5'v1-week_14-16-Mesenchymal_fibro-stroma|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

ADAMTS16 FMOD LOX

9.70e-04189463eccf3d49354a67c94f1ed7c15a98a48a5e8e2ed0
ToppCell(2)_NK/T-(210)_NKT_cell|(2)_NK/T / immune cells in Peripheral Blood (logTPM normalization)

SMARCC1 SIGLEC1 H6PD

9.70e-04189463fa72e87e1e8cd7cbddae7b47e19cf90d181820a7
ToppCellFibroblast-C|World / shred on cell class and cell subclass (v4)

FMOD LOX LRRC17

9.70e-0418946358e0400fbab5a0755504275aef5cf7986149abab
ToppCell10x3'2.3-week_12-13-Mesenchymal_fibro-stroma-endosteal_fibroblast|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

ADAMTS16 LOX LRRC17

9.70e-04189463c392491aabe8a3e90974ab2ea123bbbe5200439d
ToppCell10x5'v1-week_14-16-Mesenchymal_fibro|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

ADAMTS16 FMOD LOX

9.70e-0418946340764f461b8aa1d3a2c5a30590b7fb9307d47d09
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-PMP-PMP_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

H6PD ELOVL6 LOX

9.70e-041894633169476f98b7385706cb618c9ad64ae83a290ef0
Diseasesyndromic X-linked intellectual disability Claes-Jensen type (implicated_via_orthology)

KDM5B KDM5D KDM5A KDM5C

4.30e-124444DOID:0060809 (implicated_via_orthology)
Diseaseautism spectrum disorder (implicated_via_orthology)

NDST1 KDM5B CHD2 RIMS1 KDM5D KDM5A KDM5C

2.74e-09152447DOID:0060041 (implicated_via_orthology)
Diseasesyndromic intellectual disability (implicated_via_orthology)

KDM5B KDM5D KDM5A KDM5C

7.72e-0916444DOID:0050888 (implicated_via_orthology)
Diseaseintellectual disability (implicated_via_orthology)

NDST1 KDM5B KDM5D KDM5A KDM5C

9.31e-0875445DOID:1059 (implicated_via_orthology)
Diseasealcohol use disorder (implicated_via_orthology)

SMARCC1 KDM5B KDM5D KDM5A KDM5C

1.05e-05195445DOID:1574 (implicated_via_orthology)
Diseasecolorectal cancer (is_marker_for)

SMARCC1 CHD4 LOX KDM5C

8.87e-05157444DOID:9256 (is_marker_for)
DiseaseAutistic Disorder

KDM5B CHD4 RIMS1 KDM5C

6.15e-04261444C0004352
Diseaseresponse to mTOR inhibitor

RIMS1 USP32

6.38e-0425442EFO_0005417
Diseasecolon adenocarcinoma (is_implicated_in)

CHD4 LOX

6.90e-0426442DOID:234 (is_implicated_in)
Diseaseanogenital venereal wart (is_marker_for)

PTPN6 TLR8

6.90e-0426442DOID:11168 (is_marker_for)
DiseaseCone-Rod Dystrophy 2

PROM1 RIMS1

8.60e-0429442C3489532
Diseasehepatocellular carcinoma (is_marker_for)

SMARCC1 CHD4 KDM5C CHD5

1.04e-03301444DOID:684 (is_marker_for)
DiseaseMental Retardation, Psychosocial

NDST1 KDM5A KDM5C

1.18e-03139443C0025363
DiseaseProfound Mental Retardation

NDST1 KDM5A KDM5C

1.18e-03139443C0020796
DiseaseMental deficiency

NDST1 KDM5A KDM5C

1.18e-03139443C0917816

Protein segments in the cluster

PeptideGeneStartEntry
KIYDIWHRRHDYWLL

CHD5

1731

Q8TDI0
VYHSYDLPWFRTLSW

CDS2

116

O95674
ALRRYYLNGHWTVDW

ADAMTS16

791

Q8TE57
DHHPIVFWNLVWYFR

DENND4A

1666

Q7Z401
WAHEHSYERLWPIYN

ACP7

331

Q6ZNF0
EDDPHWWFHYLRSQQ

FMOD

21

Q06828
WLRDNPWRCDYNIHY

LRRC17

346

Q8N6Y2
EDHWSYSINYLHWGE

KDM5D

506

Q9BY66
WYATHIERWLSAYHA

NDST1

756

P52848
EDHWSYSINYLHWGE

KDM5B

501

Q9UGL1
PLWVDYFLHHDNWIH

GPR4

71

P46093
DHWSYSINYLHWGEP

KDM5A

486

P29375
DLDYYWLDPATWHSR

RIMS1

561

Q86UR5
WGRYHHYCTRSQLAW

RGR

111

P47804
HWYHHITVLLYSWYS

ELOVL6

141

Q9H5J4
VNYDWIHWDPEHSYE

GBE1

171

Q04446
LPWHNLYFWYVRTAV

PRMT7

486

Q9NVM4
PWGSDRHHQYEQHWY

CHD2

1656

O14647
RPRYSWEWHSCHQHY

LOX

281

P28300
ETYWYLWRFTHDPRY

MAN1A2

536

O60476
WITIHNPYLVAWHGY

KLB

236

Q86Z14
YFREWLYNSLWFHKH

HAS3

361

O00219
HYGFPWAHTHLWLVD

H6PD

606

O95479
YEIWHRRHDYWLLAG

CHD4

1726

Q14839
RWSTLHTEYIWYDPQ

DSEL

381

Q8IZU8
IYHLYWWEFNVHSKL

DCAF15

106

Q66K64
ITQEWHYRYEDHSPW

OSBPL5

701

Q9H0X9
SHRYDEWIYWDSNRL

PHF20L1

51

A8MW92
LSYVLWHHYALNTWL

RNF139

406

Q8WU17
HWEEYLRKWHAYETA

PKDREJ

1476

Q9NTG1
HRNLPTLEEYDSYWW

PROM1

421

O43490
HGYHYWRDRWEQFDK

SLC9A5

491

Q14940
VHWGFYPDSYDTWVH

SMARCC1

231

Q92922
HEWAHLRWGVFDEYN

CLCA1

156

A8K7I4
ALAHHLFYWDVWFIY

TLR8

846

Q9NR97
QAPHWWRTYREYFGE

MRPL38

66

Q96DV4
GHYWAYIFDHRESRW

USP25

606

Q9UHP3
PAWVTADHQYYLSLW

TMEM47

41

Q9BQJ4
AHAPTLYTWYHNGRW

SIGLEC1

1286

Q9BZZ2
AAPRHQYYNQEWTLW

UBA1

941

P22314
IREIWHYQYLSWPDH

PTPN6

406

P29350
SVPRLCWHFFYSHWN

ZDHHC16

111

Q969W1
PIYLQVSSYQHWIWD

PRSS50

341

Q9UI38
VWRALYHWYGANLAL

USP32

566

Q8NFA0
EDHWSYSINYLHWGE

KDM5C

516

P41229
VAYYLHHSPWWFHRF

LMF1

251

Q96S06