Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcesscell morphogenesis

LST1 ARHGAP32 ETV4 MGLL SIN3A NIBAN2 PRAG1 NRP2 LHX9 ENAM CCDC88C CDKL5 COL18A1 TFCP2L1 FAT1 NFIB ROBO2 IGSF9 EIF2AK4 ATOH1 CDH2 CDH5 CDH11 ARHGAP33 SOS1

2.12e-06119415225GO:0000902
GeneOntologyBiologicalProcessaxonogenesis

ARHGAP32 ETV4 MGLL SIN3A NIBAN2 NRP2 LHX9 CDKL5 NFIB ROBO2 IGSF9 ATOH1 CDH2 CDH11 SOS1

1.97e-0556615215GO:0007409
GeneOntologyBiologicalProcessgrowth

ARHGAP32 ERBB4 DCAF13 ARMC12 MGLL DLK1 SIN3A SIK3 DYSF PRDM4 ECM1 NRP2 MAGI2 CDKL5 TFCP2L1 HOXD11 MINAR1 EIF2AK4 MBD5 SMAD2 SMAD3 SOS1 WDTC1

3.70e-05123515223GO:0040007
GeneOntologyBiologicalProcesstransforming growth factor beta receptor signaling pathway

VEPH1 SIN3A LPXN LTBP2 SAP130 CDH5 SMAD2 ADAMTSL2 SMAD3 SMAD9

3.96e-0527615210GO:0007179
GeneOntologyBiologicalProcessdevelopmental growth

ARHGAP32 ERBB4 DCAF13 MGLL DLK1 SIN3A SIK3 DYSF ECM1 NRP2 MAGI2 CDKL5 HOXD11 EIF2AK4 MBD5 SMAD2 SMAD3 SOS1 WDTC1

4.24e-0591115219GO:0048589
GeneOntologyBiologicalProcessmonocyte activation involved in immune response

DYSF FER1L5

5.40e-0521522GO:0002280
GeneOntologyBiologicalProcessaxon development

ARHGAP32 ETV4 MGLL SIN3A NIBAN2 NRP2 LHX9 CDKL5 NFIB ROBO2 IGSF9 ATOH1 CDH2 CDH11 SOS1

8.27e-0564215215GO:0061564
GeneOntologyBiologicalProcessneuron projection morphogenesis

ARHGAP32 ETV4 MGLL SIN3A NIBAN2 NRP2 LHX9 CDKL5 NFIB ROBO2 IGSF9 EIF2AK4 ATOH1 CDH2 CDH11 ARHGAP33 SOS1

9.06e-0580215217GO:0048812
GeneOntologyBiologicalProcessplasma membrane bounded cell projection morphogenesis

ARHGAP32 ETV4 MGLL SIN3A NIBAN2 NRP2 LHX9 CDKL5 NFIB ROBO2 IGSF9 EIF2AK4 ATOH1 CDH2 CDH11 ARHGAP33 SOS1

1.17e-0481915217GO:0120039
GeneOntologyBiologicalProcesstranscription initiation-coupled chromatin remodeling

RBBP5 NIBAN2 ATAD2B PABPC1L SGF29

1.18e-04651525GO:0045815
GeneOntologyBiologicalProcesscell projection morphogenesis

ARHGAP32 ETV4 MGLL SIN3A NIBAN2 NRP2 LHX9 CDKL5 NFIB ROBO2 IGSF9 EIF2AK4 ATOH1 CDH2 CDH11 ARHGAP33 SOS1

1.29e-0482615217GO:0048858
GeneOntologyBiologicalProcesscell morphogenesis involved in neuron differentiation

ARHGAP32 ETV4 MGLL SIN3A NIBAN2 NRP2 LHX9 CDKL5 NFIB ROBO2 IGSF9 ATOH1 CDH2 CDH11 ARHGAP33 SOS1

1.33e-0474815216GO:0048667
GeneOntologyBiologicalProcesspositive regulation of gene expression, epigenetic

RBBP5 NIBAN2 ATAD2B PABPC1L SGF29

1.46e-04681525GO:0141137
GeneOntologyBiologicalProcessepigenetic regulation of gene expression

DCAF13 KMT2B RBBP5 ZNFX1 SIN3A NIBAN2 ATF7IP ATAD2B PABPC1L SGF29

1.73e-0433015210GO:0040029
GeneOntologyBiologicalProcesscellular response to growth factor stimulus

ERBB4 CAD VEPH1 SIN3A NIBAN2 NRP2 MAGI2 LPXN LTBP2 SAP130 CDH5 GAB1 SMAD2 ADAMTSL2 SMAD3 SMAD9 SOS1

1.82e-0485015217GO:0071363
GeneOntologyBiologicalProcessneuron projection development

LST1 ARHGAP32 ETV4 MGLL SIN3A NIBAN2 PRAG1 NRP2 LHX9 MAGI2 CDKL5 GDPD5 NFIB ROBO2 IGSF9 MINAR1 EIF2AK4 ATOH1 CDH2 CDH11 ARHGAP33 SOS1

1.88e-04128515222GO:0031175
GeneOntologyBiologicalProcesscellular response to transforming growth factor beta stimulus

VEPH1 SIN3A LPXN LTBP2 SAP130 CDH5 SMAD2 ADAMTSL2 SMAD3 SMAD9

2.00e-0433615210GO:0071560
GeneOntologyBiologicalProcessresponse to transforming growth factor beta

VEPH1 SIN3A LPXN LTBP2 SAP130 CDH5 SMAD2 ADAMTSL2 SMAD3 SMAD9

2.36e-0434315210GO:0071559
GeneOntologyBiologicalProcessaxon guidance

ETV4 NIBAN2 NRP2 LHX9 NFIB ROBO2 IGSF9 ATOH1 SOS1

2.71e-042851529GO:0007411
GeneOntologyBiologicalProcessneuron projection guidance

ETV4 NIBAN2 NRP2 LHX9 NFIB ROBO2 IGSF9 ATOH1 SOS1

2.78e-042861529GO:0097485
GeneOntologyBiologicalProcessresponse to growth factor

ERBB4 CAD VEPH1 SIN3A NIBAN2 NRP2 MAGI2 LPXN LTBP2 SAP130 CDH5 GAB1 SMAD2 ADAMTSL2 SMAD3 SMAD9 SOS1

2.83e-0488315217GO:0070848
GeneOntologyBiologicalProcessneuroligin clustering involved in postsynaptic membrane assembly

MAGI2 CDH2

3.21e-0441522GO:0097118
GeneOntologyCellularComponentheteromeric SMAD protein complex

SMAD2 SMAD3 SMAD9

2.06e-0581523GO:0071144
GeneOntologyCellularComponentSMAD protein complex

SMAD2 SMAD3 SMAD9

4.36e-05101523GO:0071141
GeneOntologyCellularComponentCul4-RING E3 ubiquitin ligase complex

DCAF15 DCAF13 DCAF5 WDTC1

1.64e-04381524GO:0080008
DomainMAD_homology1_Dwarfin-type

NFIB SMAD2 SMAD3 SMAD9

1.83e-06121494IPR003619
DomainDWA

NFIB SMAD2 SMAD3 SMAD9

1.83e-06121494SM00523
DomainMH1

NFIB SMAD2 SMAD3 SMAD9

1.83e-06121494PF03165
DomainDWB

SMAD2 SMAD3 SMAD9

2.71e-0581493SM00524
DomainMH2

SMAD2 SMAD3 SMAD9

2.71e-0581493PS51076
DomainMH1

SMAD2 SMAD3 SMAD9

2.71e-0581493PS51075
Domain-

SMAD2 SMAD3 SMAD9

2.71e-05814933.90.520.10
DomainMAD_homology_MH1

SMAD2 SMAD3 SMAD9

2.71e-0581493IPR013019
DomainDwarfin

SMAD2 SMAD3 SMAD9

2.71e-0581493IPR013790
DomainMH2

SMAD2 SMAD3 SMAD9

2.71e-0581493PF03166
DomainSMAD_dom_Dwarfin-type

SMAD2 SMAD3 SMAD9

2.71e-0581493IPR001132
DomainFerA

DYSF FER1L5

1.89e-0431492SM01200
DomainFerlin_A-domain

DYSF FER1L5

1.89e-0431492IPR012560
DomainFerA

DYSF FER1L5

1.89e-0431492PF08165
DomainLatrophilin

ADGRL2 ADGRL3

1.89e-0431492PF02354
DomainGPCR_2_latrophilin_rcpt_C

ADGRL2 ADGRL3

1.89e-0431492IPR003334
DomainSMAD_dom-like

SMAD2 SMAD3 SMAD9

2.58e-04161493IPR017855
Domain-

SMAD2 SMAD3 SMAD9

2.58e-041614932.60.200.10
DomainCA

FREM2 FAT1 FAT2 CDH2 CDH5 CDH11

3.21e-041151496SM00112
DomainCadherin

FREM2 FAT1 FAT2 CDH2 CDH5 CDH11

3.69e-041181496IPR002126
DomainDysFC

DYSF FER1L5

3.75e-0441492SM00694
DomainDysFN

DYSF FER1L5

3.75e-0441492SM00693
DomainPeroxin/Ferlin

DYSF FER1L5

3.75e-0441492IPR006614
Domaindsrm

DHX30 STAU1 DROSHA

5.13e-04201493PF00035
DomainDS_RBD

DHX30 STAU1 DROSHA

5.96e-04211493PS50137
DomainFerI

DYSF FER1L5

6.22e-0451492SM01202
DomainFerB

DYSF FER1L5

6.22e-0451492SM01201
DomainFerlin_B-domain

DYSF FER1L5

6.22e-0451492IPR012561
DomainFerlin_C

DYSF FER1L5

6.22e-0451492PF16165
DomainFerlin_C

DYSF FER1L5

6.22e-0451492IPR032362
DomainFerIin_dom

DYSF FER1L5

6.22e-0451492IPR012968
DomainFerI

DYSF FER1L5

6.22e-0451492PF08151
DomainFerB

DYSF FER1L5

6.22e-0451492PF08150
DomainGal_Lectin

ADGRL2 ADGRL3

6.22e-0451492PF02140
DomainGPCR_2_latrophilin

ADGRL2 ADGRL3

6.22e-0451492IPR003924
DomainLectin_gal-bd_dom

ADGRL2 ADGRL3

6.22e-0451492IPR000922
DomainSUEL_LECTIN

ADGRL2 ADGRL3

6.22e-0451492PS50228
Domain-

UBE2L6 RNF25 UBE2T EIF2AK4

7.27e-045114943.10.110.10
DomainSMAD_FHA_domain

MKI67 SMAD2 SMAD3 SMAD9

7.82e-04521494IPR008984
DomainUBQ-conjugating_enzyme/RWD

UBE2L6 RNF25 UBE2T EIF2AK4

8.41e-04531494IPR016135
DomainCadherin_C

CDH2 CDH5 CDH11

1.01e-03251493PF01049
DomainCadherin_cytoplasmic-dom

CDH2 CDH5 CDH11

1.01e-03251493IPR000233
DomainWD40

DCAF13 RAE1 RBBP5 DCAF5 THOC6 ZNF106 WDFY3 WDTC1

1.14e-032591498PF00400
DomainWD40

DCAF13 RAE1 RBBP5 DCAF5 THOC6 ZNF106 WDFY3 WDTC1

1.41e-032681498SM00320
DomainWD40_repeat

DCAF13 RAE1 RBBP5 DCAF5 THOC6 ZNF106 WDFY3 WDTC1

1.55e-032721498IPR001680
DomainCatenin_binding_dom

CDH2 CDH5 CDH11

1.56e-03291493IPR027397
Domain-

CDH2 CDH5 CDH11

1.56e-032914934.10.900.10
DomainWD_REPEATS_1

DCAF13 RAE1 RBBP5 DCAF5 THOC6 ZNF106 WDFY3 WDTC1

1.78e-032781498PS00678
DomainCadherin_CS

FAT1 FAT2 CDH2 CDH5 CDH11

1.81e-031091495IPR020894
DomainWD_REPEATS_2

DCAF13 RAE1 RBBP5 DCAF5 THOC6 ZNF106 WDFY3 WDTC1

1.82e-032791498PS50082
DomainWD_REPEATS_REGION

DCAF13 RAE1 RBBP5 DCAF5 THOC6 ZNF106 WDFY3 WDTC1

1.82e-032791498PS50294
DomainCADHERIN_1

FAT1 FAT2 CDH2 CDH5 CDH11

2.13e-031131495PS00232
DomainCadherin

FAT1 FAT2 CDH2 CDH5 CDH11

2.13e-031131495PF00028
DomainCADHERIN_2

FAT1 FAT2 CDH2 CDH5 CDH11

2.21e-031141495PS50268
Domain-

FAT1 FAT2 CDH2 CDH5 CDH11

2.21e-0311414952.60.40.60
DomainCadherin-like

FAT1 FAT2 CDH2 CDH5 CDH11

2.38e-031161495IPR015919
DomainWD40_repeat_dom

DCAF13 RAE1 RBBP5 DCAF5 THOC6 ZNF106 WDFY3 WDTC1

2.68e-032971498IPR017986
DomainRWD

RNF25 EIF2AK4

2.73e-03101492PS50908
DomainGPS

PKD1L1 ADGRL2 ADGRL3

2.93e-03361493PS50221
DomainEGF_CA

DLK1 LRP1B FAT1 FAT2 LTBP2

2.96e-031221495SM00179
DomainGPS

PKD1L1 ADGRL2 ADGRL3

3.17e-03371493IPR000203
DomainEGF-like_Ca-bd_dom

DLK1 LRP1B FAT1 FAT2 LTBP2

3.18e-031241495IPR001881
DomainRWD

RNF25 EIF2AK4

3.32e-03111492SM00591
DomainGAIN_dom_N

ADGRL2 ADGRL3

3.32e-03111492IPR032471
DomainRWD

RNF25 EIF2AK4

3.32e-03111492PF05773
DomainGAIN

ADGRL2 ADGRL3

3.32e-03111492PF16489
DomainEGF

DLK1 LRP1B FAT1 FAT2 LTBP2

3.41e-031261495PF00008
DomainRWD-domain

RNF25 EIF2AK4

3.96e-03121492IPR006575
DomainOLF

ADGRL2 ADGRL3

4.65e-03131492PF02191
DomainOLF

ADGRL2 ADGRL3

4.65e-03131492PS51132
DomainOlfac-like_dom

ADGRL2 ADGRL3

4.65e-03131492IPR003112
DomainOLF

ADGRL2 ADGRL3

4.65e-03131492SM00284
DomainLamG

COL18A1 FAT1 FAT2

5.19e-03441493SM00282
Domain-

DCAF13 RAE1 RBBP5 DCAF5 THOC6 ZNF106 WDFY3 WDTC1

5.33e-0333314982.130.10.10
DomainPB1

MAP3K3 MAP3K2

5.40e-03141492SM00666
DomainPB1

MAP3K3 MAP3K2

5.40e-03141492PF00564
DomainPB1

MAP3K3 MAP3K2

5.40e-03141492PS51745
DomainPB1_dom

MAP3K3 MAP3K2

5.40e-03141492IPR000270
DomainWD40/YVTN_repeat-like_dom

DCAF13 RAE1 RBBP5 DCAF5 THOC6 ZNF106 WDFY3 WDTC1

5.52e-033351498IPR015943
DomainCUB

TMPRSS15 NRP2 SEZ6L

7.01e-03491493PF00431
DomainCUB

TMPRSS15 NRP2 SEZ6L

7.42e-03501493SM00042
DomainMAM

TMPRSS15 NRP2

7.95e-03171492SM00137
Pubmed

Human transcription factor protein interaction networks.

ARHGAP32 CAD KMT2B RBBP5 RC3H1 ETV4 SIN3A LASP1 SOX13 LIN9 DCAF5 DHX30 STAU1 FAT1 HOXD11 NFIB SPZ1 ATF7IP SEC16A MKI67 HELZ PABPC1L SGF29 SAP130 CNOT2

3.34e-0914291522535140242
Pubmed

A human MAP kinase interactome.

ARHGAP32 SYNPO2 HIVEP2 SIK3 MAP3K3 ZNF106 ATF7IP SIMC1 HELZ CGNL1 MBD5 GAB1 ARHGAP33 MAP3K2 SOS1

4.25e-094861521520936779
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

ARHGAP32 ERBB4 HIVEP2 TBC1D5 RIPK2 SIK3 PTPN21 DPP8 PRAG1 MAP3K3 CCDC88C ZNF106 SEC16A HELZ CGNL1 USP6NL AQR GAB1 MAP3K2

8.21e-098611521936931259
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

A2M RBBP5 TBC1D5 ZNFX1 SIN3A COLGALT2 SIK3 INTS3 FREM2 EIF2D DROSHA TPP1 DDHD1 HELZ EIF2AK4 AQR

3.02e-086501521638777146
Pubmed

Functional proteomics mapping of a human signaling pathway.

A2M KMT2B CPXM2 NIBAN2 PRDM4 SOX13 DHX30 STAU1 ZNF106 DROSHA ATF7IP SAP130 SMAD2 SMAD3 SMAD9

5.62e-085911521515231748
Pubmed

Smad2/Smad3 in endothelium is indispensable for vascular stability via S1PR1 and N-cadherin expressions.

CDH2 CDH5 SMAD2 SMAD3

1.13e-0711152422498737
Pubmed

Activin A, B, and AB increase human trophoblast cell invasion by up-regulating N-cadherin.

CDH2 SMAD2 SMAD3

3.26e-074152325105734
Pubmed

The chromatin regulator Ankrd11 controls cardiac neural crest cell-mediated outflow tract remodeling and heart function.

MKI67 SMAD2 SMAD3 SMAD9

3.39e-0714152438951500
Pubmed

The function of growth/differentiation factor 11 (Gdf11) in rostrocaudal patterning of the developing spinal cord.

ETV4 SMAD2 SMAD3 SMAD9

3.39e-0714152416790475
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

ERBB4 RAE1 ZNF618 SIN3A SIK3 DCAF5 FAT1 DROSHA SEC16A HELZ WDFY3 MTO1 ADGRL2 SGF29 SAP130 ARHGAP33 SEZ6L SOS1 WDTC1

4.62e-0711161521931753913
Pubmed

Spatial and temporal expression of molecular markers and cell signals during normal development of the mouse patellar tendon.

MKI67 SMAD2 SMAD3 SMAD9

6.13e-0716152421939397
Pubmed

SMAD4 is essential for generating subtypes of neurons during cerebellar development.

MKI67 ATOH1 SMAD2 SMAD9

7.98e-0717152422370000
Pubmed

Role of RbBP5 and H3K4me3 in the vicinity of Snail transcription start site during epithelial-mesenchymal transition in prostate cancer cell.

RBBP5 SMAD2 SMAD3

8.13e-075152327566588
Pubmed

Identification and characterization of a PDZ protein that interacts with activin type II receptors.

MAGI2 SMAD2 SMAD3

8.13e-075152310681527
Pubmed

Brightfield proximity ligation assay reveals both canonical and mixed transforming growth factor-β/bone morphogenetic protein Smad signaling complexes in tissue sections.

SMAD2 SMAD3 SMAD9

8.13e-075152325141865
Pubmed

TGF-beta signalling is regulated by Schnurri-2-dependent nuclear translocation of CLIC4 and consequent stabilization of phospho-Smad2 and 3.

HIVEP2 SMAD2 SMAD3

8.13e-075152319448624
Pubmed

Smad7 is required for the development and function of the heart.

SMAD2 SMAD3 SMAD9

1.62e-066152318952608
Pubmed

Dynamic regulation of Smad expression during mesenchyme to epithelium transition in the metanephric kidney.

SMAD2 SMAD3 SMAD9

1.62e-066152311850197
Pubmed

Inflammation-dependent overexpression of c-Myc enhances CRL4DCAF4 E3 ligase activity and promotes ubiquitination of ST7 in colitis-associated cancer.

LST1 RBBP5 SIN3A DCAF5 STAU1 GAB1 SMAD2 SMAD3 WDTC1

2.14e-06257152930945288
Pubmed

Regulation of transforming growth factor-beta and bone morphogenetic protein signalling by transcriptional coactivator GCN5.

SMAD2 SMAD3 SMAD9

2.83e-067152315009097
Pubmed

Negative regulation of BMP/Smad signaling by Tob in osteoblasts.

SMAD2 SMAD3 SMAD9

2.83e-067152311163184
Pubmed

c-Ski acts as a transcriptional co-repressor in transforming growth factor-beta signaling through interaction with smads.

SIN3A SMAD2 SMAD3

2.83e-067152310575014
Pubmed

Pkd1 is required for male reproductive tract development.

MKI67 SMAD2 SMAD3

2.83e-067152323933588
Pubmed

Transposon mutagenesis with coat color genotyping identifies an essential role for Skor2 in sonic hedgehog signaling and cerebellum development.

SAP130 SMAD2 SMAD3 SMAD9

2.91e-0623152421937600
Pubmed

Airway basal stem cells reutilize the embryonic proliferation regulator, Tgfβ-Id2 axis, for tissue regeneration.

MKI67 SMAD2 SMAD3 SMAD9

3.48e-0624152434129836
Pubmed

Interaction network of human early embryonic transcription factors.

HIVEP2 KMT2B RAE1 RBBP5 SOX13 LIN9 NFIB SEC16A MKI67 CDH2

3.64e-063511521038297188
Pubmed

Yap1 is required for endothelial to mesenchymal transition of the atrioventricular cushion.

MKI67 CDH5 SMAD2 SMAD3

4.13e-0625152424831012
Pubmed

A new nonsense mutation of SMAD8 associated with pulmonary arterial hypertension.

SMAD2 SMAD3 SMAD9

4.51e-068152319211612
Pubmed

Remarkable versatility of Smad proteins in the nucleus of transforming growth factor-beta activated cells.

SMAD2 SMAD3 SMAD9

4.51e-068152310647776
Pubmed

Smad7 Regulates Dental Epithelial Proliferation during Tooth Development.

MKI67 SMAD2 SMAD3

4.51e-068152331499015
Pubmed

Computational modelling of Smad-mediated negative feedback and crosstalk in the TGF-β superfamily network.

SMAD2 SMAD3 SMAD9

4.51e-068152323804438
Pubmed

TGF-beta signaling by Smad proteins.

SMAD2 SMAD3 SMAD9

4.51e-068152310708949
Pubmed

Loss of Sox9 in the periotic mesenchyme affects mesenchymal expansion and differentiation, and epithelial morphogenesis during cochlea development in the mouse.

ETV4 SMAD2 SMAD3 SMAD9

6.62e-0628152420346939
Pubmed

GATA4 is essential for bone mineralization via ERα and TGFβ/BMP pathways.

SMAD2 SMAD3 SMAD9

6.74e-069152324932701
Pubmed

Peg3/PW1 Is a Marker of a Subset of Vessel Associated Endothelial Progenitors.

MKI67 CDH5 SMAD3

6.74e-069152328090691
Pubmed

Smad7 Protein Interacts with Receptor-regulated Smads (R-Smads) to Inhibit Transforming Growth Factor-β (TGF-β)/Smad Signaling.

SMAD2 SMAD3 SMAD9

6.74e-069152326555259
Pubmed

Holding their own: the noncanonical roles of Smad proteins.

SMAD2 SMAD3 SMAD9

6.74e-069152319018011
Pubmed

TGF-beta signal transduction.

SMAD2 SMAD3 SMAD9

6.74e-06915239759503
Pubmed

Combinatorial Smad2/3 Activities Downstream of Nodal Signaling Maintain Embryonic/Extra-Embryonic Cell Identities during Lineage Priming.

SMAD2 SMAD3 SMAD9

6.74e-069152330134160
Pubmed

Interactions between BMP-7 and USAG-1 (uterine sensitization-associated gene-1) regulate supernumerary organ formations.

SMAD2 SMAD3 SMAD9

6.74e-069152324816837
Pubmed

Dullard/Ctdnep1 regulates endochondral ossification via suppression of TGF-β signaling.

SMAD2 SMAD3 SMAD9

6.74e-069152325155999
Pubmed

In vivo regulation of TGF-β by R-Ras2 revealed through loss of the RasGAP protein NF1.

MKI67 SMAD2 SMAD3

6.74e-069152322918885
Pubmed

The Smad pathway.

SMAD2 SMAD3 SMAD9

6.74e-069152310708948
Pubmed

Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

ZNF862 COLGALT2 PHLPP1 GREB1 AQR ADAMTSL2

7.11e-0610515269628581
Pubmed

Restrictive loss of plakoglobin in cardiomyocytes leads to arrhythmogenic cardiomyopathy.

MKI67 CDH2 SMAD2 SMAD9

8.80e-0630152421880664
Pubmed

TGF-β signaling inhibits canonical BMP signaling pathway during palate development.

SMAD2 SMAD3 SMAD9

9.60e-0610152329247325
Pubmed

Spatio-temporal distribution of Smads and role of Smads/TGF-β/BMP-4 in the regulation of mouse bladder organogenesis.

SMAD2 SMAD3 SMAD9

9.60e-0610152323620745
Pubmed

Protein Arginine Methyltransferase PRMT1 Is Essential for Palatogenesis.

SMAD2 SMAD3 SMAD9

9.60e-0610152329986157
Pubmed

Diversity of the cadherin family: evidence for eight new cadherins in nervous tissue.

CDH2 CDH5 CDH11

9.60e-061015232059658
Pubmed

Essential roles of inhibin beta A in mouse epididymal coiling.

MKI67 SMAD2 SMAD3

9.60e-0610152317592132
Pubmed

Adamtsl2 deletion results in bronchial fibrillin microfibril accumulation and bronchial epithelial dysplasia--a novel mouse model providing insights into geleophysic dysplasia.

SMAD2 ADAMTSL2 SMAD3 SMAD9

1.01e-0531152425762570
Pubmed

The non-canonical BMP and Wnt/β-catenin signaling pathways orchestrate early tooth development.

ETV4 SMAD2 SMAD3 SMAD9

1.15e-0532152425428587
Pubmed

Lhx2 is a direct NF-κB target gene that promotes primary hair follicle placode down-growth.

ETV4 NRP2 MKI67 SMAD2

1.30e-0533152426952977
Pubmed

Versican facilitates chondrocyte differentiation and regulates joint morphogenesis.

MKI67 SMAD2 SMAD3

1.32e-0511152320404343
Pubmed

Smad2 and Smad3 Regulate Chondrocyte Proliferation and Differentiation in the Growth Plate.

SMAD2 SMAD3 SMAD9

1.32e-0511152327741240
Pubmed

BMP receptor-activated Smads confer diverse functions during the development of the dorsal spinal cord.

LHX9 ATOH1 SMAD9

1.32e-0511152322609550
Pubmed

Downregulation of bone morphogenetic protein receptor axis during HIV-1 and cocaine-mediated pulmonary smooth muscle hyperplasia: implications for HIV-related pulmonary arterial hypertension.

SMAD2 SMAD3 SMAD9

1.32e-0511152324008158
Pubmed

FKBP8 cell-autonomously controls neural tube patterning through a Gli2- and Kif3a-dependent mechanism.

LHX9 MKI67 ATOH1 SMAD9

1.47e-0534152418590716
Pubmed

β-Catenin regulates endocardial cushion growth by suppressing p21.

ERBB4 MKI67 CDH5 SMAD9

1.65e-0535152437385754
Pubmed

BMPR-II is dispensable for formation of the limb skeleton.

SMAD2 SMAD3 SMAD9

1.75e-0512152321538804
Pubmed

Laminar organization of the developing lateral olfactory tract revealed by differential expression of cell recognition molecules.

ERBB4 NRP2 ROBO2

1.75e-0512152315457507
Pubmed

Smad expression during kidney development.

SMAD2 SMAD3 SMAD9

1.75e-0512152314656760
Pubmed

Regulation of TGF-beta signalling by Fbxo11, the gene mutated in the Jeff otitis media mouse mutant.

MKI67 SMAD2 SMAD3

1.75e-0512152319580641
Pubmed

Amelogenesis imperfecta in a new animal model--a mutation in chromosome 5 (human 4q21).

ENAM CSN3 WDFY3

1.75e-0512152315271968
Pubmed

Generation of Cajal-Retzius neurons in mouse forebrain is regulated by transforming growth factor beta-Fox signaling pathways.

MKI67 SMAD2 SMAD3

1.75e-0512152318005957
Pubmed

Crim1KST264/KST264 mice implicate Crim1 in the regulation of vascular endothelial growth factor-A activity during glomerular vascular development.

SMAD2 SMAD3 SMAD9

1.75e-0512152317460146
Pubmed

A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.

ARHGAP32 ERBB4 NIBAN2 SEC16A ROBO2 ADGRL2 CDH2 USP6NL GAB1 SMAD2

1.77e-054211521036976175
Pubmed

The kinases MEKK2 and MEKK3 regulate transforming growth factor-β-mediated helper T cell differentiation.

MAP3K3 MAP3K2

1.90e-052152221333552
Pubmed

Lack of extracellular matrix switches TGF-β induced apoptosis of endometrial cells to epithelial to mesenchymal transition.

SMAD2 SMAD3

1.90e-052152236050359
Pubmed

Receptor-regulated and inhibitory Smads are critical in regulating transforming growth factor beta-mediated Meckel's cartilage development.

SMAD2 SMAD3

1.90e-052152211984875
Pubmed

Polycomb determines responses to smad2/3 signaling in embryonic stem cell differentiation and in reprogramming.

SMAD2 SMAD3

1.90e-052152223666711
Pubmed

Phosphorylated Smad2/3 immunoreactivity in sporadic and familial amyotrophic lateral sclerosis and its mouse model.

SMAD2 SMAD3

1.90e-052152218210139
Pubmed

Gingipains from Porphyromonas gingivalis W83 induce cell adhesion molecule cleavage and apoptosis in endothelial cells.

CDH2 CDH5

1.90e-052152215731052
Pubmed

Smad2 and Smad3 have opposing roles in breast cancer bone metastasis by differentially affecting tumor angiogenesis.

SMAD2 SMAD3

1.90e-052152220010874
Pubmed

Deletion of Smad2 in mouse liver reveals novel functions in hepatocyte growth and differentiation.

SMAD2 SMAD3

1.90e-052152216382155
Pubmed

Molecular cloning of mitogen-activated protein/ERK kinase kinases (MEKK) 2 and 3. Regulation of sequential phosphorylation pathways involving mitogen-activated protein kinase and c-Jun kinase.

MAP3K3 MAP3K2

1.90e-05215228621389
Pubmed

CDH2 and CDH11 act as regulators of stem cell fate decisions.

CDH2 CDH11

1.90e-052152225771201
Pubmed

Evidence for a role of Smad3 and Smad2 in stabilization of the tumor-derived mutant Smad2.Q407R.

SMAD2 SMAD3

1.90e-052152212700238
Pubmed

Asthma-derived fibroblast to myofibroblast transition is enhanced in comparison to fibroblasts derived from non-asthmatic patients in 3D in vitro culture due to Smad2/3 signalling.

SMAD2 SMAD3

1.90e-052152233245228
Pubmed

KMT2B promotes SHPRH expression to regulate 131I sensitivity in thyroid carcinoma cells by affecting FYN protein stability.

KMT2B SHPRH

1.90e-052152234606908
Pubmed

Formation of the definitive endoderm in mouse is a Smad2-dependent process.

SMAD2 SMAD3

1.90e-052152210862745
Pubmed

Smad2-dependent downregulation of miR-30 is required for TGF-β-induced apoptosis in podocytes.

SMAD2 SMAD3

1.90e-052152224086574
Pubmed

Specific Smad2/3 Linker Phosphorylation Indicates Esophageal Non-neoplastic and Neoplastic Stem-Like Cells and Neoplastic Development.

SMAD2 SMAD3

1.90e-052152232705438
Pubmed

Latrophilin GPCRs direct synapse specificity by coincident binding of FLRTs and teneurins.

ADGRL2 ADGRL3

1.90e-052152230792275
Pubmed

Smad2/3 Linker Phosphorylation Is a Possible Marker of Pancreatic Stem/Progenitor Cells in the Regenerative Phase of Acute Pancreatitis.

SMAD2 SMAD3

1.90e-052152228099259
Pubmed

Arsenite Disrupts Zinc-Dependent TGFβ2-SMAD Activity During Murine Cardiac Progenitor Cell Differentiation.

SMAD2 SMAD3

1.90e-052152226354774
Pubmed

Differential effects of Smad2 and Smad3 in regulation of macrophage phenotype and function in the infarcted myocardium.

SMAD2 SMAD3

1.90e-052152235780861
Pubmed

Constitutively Active SMAD2/3 Are Broad-Scope Potentiators of Transcription-Factor-Mediated Cellular Reprogramming.

SMAD2 SMAD3

1.90e-052152229174331
Pubmed

Coexpression of two mesenchymal cadherins, cadherin 11 and N-cadherin, on murine fibroblast-like synoviocytes.

CDH2 CDH11

1.90e-052152218383368
Pubmed

SMAD2/3 Phosphorylation Is Downregulated in T Cells in HIV-Infected Patients.

SMAD2 SMAD3

1.90e-052152236226468
Pubmed

Phosphorylation of Smad2/3 at specific linker threonine indicates slow-cycling intestinal stem-like cells before reentry to cell cycle.

SMAD2 SMAD3

1.90e-052152225185661
Pubmed

Increased TGF-β1-mediated suppression of growth and motility in castrate-resistant prostate cancer cells is consistent with Smad2/3 signaling.

SMAD2 SMAD3

1.90e-052152222228025
Pubmed

Oocyte-secreted factor activation of SMAD 2/3 signaling enables initiation of mouse cumulus cell expansion.

SMAD2 SMAD3

1.90e-052152217192514
Pubmed

Latrophilin GPCR signaling mediates synapse formation.

ADGRL2 ADGRL3

1.90e-052152233646123
Pubmed

TGFβ pathway deregulation and abnormal phospho-SMAD2/3 staining in hereditary cerebral hemorrhage with amyloidosis-Dutch type.

SMAD2 SMAD3

1.90e-052152228557134
Pubmed

Insulin-like growth factor-1 enhances inflammatory responses in endothelial cells: role of Gab1 and MEKK3 in TNF-alpha-induced c-Jun and NF-kappaB activation and adhesion molecule expression.

MAP3K3 GAB1

1.90e-052152212065326
Pubmed

Differential activation of noncanonical SMAD2/SMAD3 signaling by bone morphogenetic proteins causes disproportionate induction of hyaluronan production in immortalized human granulosa cells.

SMAD2 SMAD3

1.90e-052152226992562
Pubmed

Global analysis of Smad2/3-dependent TGF-beta signaling in living mice reveals prominent tissue-specific responses to injury.

SMAD2 SMAD3

1.90e-052152215972691
Pubmed

Enrichment of human ESC-derived multipotent mesenchymal stem cells with immunosuppressive and anti-inflammatory properties capable to protect against experimental inflammatory bowel disease.

SMAD2 SMAD3

1.90e-052152221732483
Pubmed

Smad2 and 3 transcription factors control muscle mass in adulthood.

SMAD2 SMAD3

1.90e-052152219357234
InteractionSH2D2A interactions

ERBB4 LASP1 GAB1 SMAD2 SMAD3 MAP3K2

2.45e-06521516int:SH2D2A
InteractionDUSP16 interactions

ERBB4 CAD ATG2B SIK3 HAUS1 SEC16A KCTD20 HELZ EIF2AK4 DNAJB5

1.23e-0523715110int:DUSP16
InteractionYWHAG interactions

ARHGAP32 SYNPO2 CAD HIVEP2 UBE2L6 TBC1D5 RC3H1 RIPK2 SIK3 PTPN21 PRAG1 MAP3K3 CCDC88C ZNF106 SIMC1 SEC16A SHPRH HELZ CGNL1 C2orf49 USP6NL AQR GAB1 MAP3K2

1.89e-05124815124int:YWHAG
InteractionPAPPA interactions

ATF7IP SMAD2 SMAD3 SMAD9

1.99e-05221514int:PAPPA
InteractionCTNNB1 interactions

ARHGAP32 CAD UBE2L6 RAE1 RBBP5 STAU1 MAGI2 CCDC88C CDKL5 YOD1 SEC16A MKI67 CGNL1 CDH2 CDH5 CNOT2 USP6NL CDH11 SMAD2 SMAD3 MAP3K2

2.12e-05100915121int:CTNNB1
InteractionDCAF4 interactions

DCAF15 ARHGAP32 DCAF13 RBBP5 RC3H1 SIN3A DCAF5 DHX30 STAU1 SEC16A HELZ SMAD3

2.88e-0537815112int:DCAF4
InteractionCYP11A1 interactions

SMAD2 SMAD3 SMAD9

3.35e-0591513int:CYP11A1
InteractionCEP85 interactions

ARHGAP32 RC3H1 PTPN21 SOX13 STAU1 SEC16A HELZ CNOT2

4.16e-051691518int:CEP85
GeneFamilyWD repeat domain containing|DDB1 and CUL4 associated factors

DCAF15 DCAF13 DCAF5 WDTC1

2.75e-06181024498
GeneFamilySMAD family

SMAD2 SMAD3 SMAD9

9.56e-0681023750
GeneFamilyUPF1 like RNA helicases

ZNFX1 HELZ AQR

2.78e-051110231169
GeneFamilyAdhesion G protein-coupled receptors, subfamily L

ADGRL2 ADGRL3

1.88e-0441022918
GeneFamilyFerlin family

DYSF FER1L5

4.66e-0461022828
GeneFamilyWD repeat domain containing

DCAF13 RAE1 RBBP5 DCAF5 THOC6 WDFY3 WDTC1

7.10e-042621027362
GeneFamilyCD molecules|Type II classical cadherins

CDH5 CDH11

2.36e-031310221186
GeneFamilyCadherin related

FAT1 FAT2

4.06e-0317102224
CoexpressionDAZARD_RESPONSE_TO_UV_NHEK_DN

HIVEP2 FAT1 FAT2 MKI67 PHLPP1 TMEM131L HELZ WDFY3 ADGRL2 CNOT2 USP6NL SMAD3

1.85e-0730015112M8702
CoexpressionGSE7568_CTRL_VS_3H_TGFB_TREATED_MACROPHAGES_WITH_IL4_AND_DEXAMETHASONE_DN

ATG2B RNF25 SIK3 LIN9 MAP3K3 STAU1 PHLPP1 SGF29

5.89e-061671518M361
CoexpressionGSE24634_NAIVE_CD4_TCELL_VS_DAY10_IL4_CONV_TREG_UP

ARHGAP32 RIPK2 NRP2 TFCP2L1 GZMM LTBP2 ADGRL2 SGF29

2.03e-051981518M4596
CoexpressionDAZARD_UV_RESPONSE_CLUSTER_G6

FAT1 FAT2 MKI67 PHLPP1 ADGRL2 CNOT2 SMAD3

2.18e-051451517M1810
ToppCell-Unknown-Endothelial-Myofibroblast| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MAGI2 EIF2D ATF7IP ATAD2B SHPRH CNOT2 GAB1 SMAD3 SCAI

1.80e-0818815296468fa95ad0395395301115286f2d8c0df5d3882
ToppCell-Unknown-Endothelial| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MAGI2 EIF2D ATF7IP ATAD2B SHPRH CNOT2 GAB1 SMAD3 SCAI

1.80e-0818815297a81ac5c79c3eb26639b52d2b9fd5e7ef9798fd6
ToppCell-Unknown| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MAGI2 EIF2D ATF7IP ATAD2B SHPRH CNOT2 GAB1 SMAD3 SCAI

1.80e-0818815299cb718bfe1358c6fd842f096e228eb0abb9aefc6
ToppCellFetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

A2M SYNPO2 PRAG1 FAT1 NFIB ROBO2 LTBP2 GREB1 ADGRL3

2.16e-08192152972881b280a415e65f87a80ca1369cbb0b722a0c4
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM1_(8)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

SYNPO2 ETV4 FAT1 KCNJ2 ROBO2 GREB1 CDH11 ADAMTSL2 SMAD3

2.26e-081931529e2b455387d1de7812305200a2041a0f4759a6f54
ToppCellBronchial-NucSeq-Epithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ARHGAP32 ERBB4 VEPH1 MGLL CDKL5 FREM2 TFCP2L1 CGNL1 SCAI

2.94e-0819915295f7da3eab58ace6cddb3179a415cd839d5767958
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ERBB4 ETV4 MGLL LRP1B MAGI2 TFCP2L1 ROBO2 CGNL1

2.10e-07181152822363c5835dd6cef8f895ab9362e0837d92b15b1
ToppCellFetal_29-31_weeks-Mesenchymal-myofibroblast_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SYNPO2 MAGI2 FAT1 NFIB ROBO2 LTBP2 GREB1 ADAMTSL2

2.70e-071871528c104fbfef2d0bef64077ac721edf2379fd59d547
ToppCell5'-GW_trimst-1.5-SmallIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

A2M DYSF SOX13 CCDC88C GDPD5 KCNJ2 CGNL1 CDH5

3.30e-0719215285a0615fdc217554ccd611504b16e5d97628e207d
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM1_(8)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

SYNPO2 ETV4 PRAG1 FAT1 ROBO2 GREB1 CDH11 ADAMTSL2

3.57e-071941528fb80a0271ccb1cb3f954ebcf2c5945cb6adb6b8c
ToppCellASK428-Mesenchymal|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq

A2M SYNPO2 ETV4 ECM1 COL18A1 ROBO2 LTBP2 CDH11

3.71e-0719515282b156163975d9a3d3fda1402acd9831d0fdc9e25
ToppCellASK428-Mesenchymal-Fibroblast|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq

A2M SYNPO2 ETV4 ECM1 COL18A1 ROBO2 LTBP2 CDH11

3.71e-071951528c269c0d894a0f55da6495b59d4b9abb9f68df684
ToppCellBronchial-NucSeq|Bronchial / Cell types per location group and 10X technology with lineage, and cell group designations

ERBB4 TBC1D5 VEPH1 SIK3 MAGI2 MBD5 GAB1 SOS1

3.86e-071961528ab53c742866945545a92e2e61850d63c80d9a2a6
ToppCellParenchymal-NucSeq|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations

ARHGAP32 ERBB4 TBC1D5 SIK3 MAGI2 WDFY3 MBD5 GAB1

4.16e-0719815281996373bdccc55aac347d349bd22f6aad6d0c668
ToppCellBronchial-NucSeq-Epithelial-Epi_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ERBB4 VEPH1 MGLL CDKL5 FREM2 CGNL1 GAB1 SCAI

4.33e-071991528725610310e5c5fd7120c0be9acb55bf152026ddd
ToppCellTracheal-NucSeq|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations

ARHGAP32 ERBB4 TBC1D5 SIK3 MAGI2 WDFY3 MBD5 SOS1

4.33e-07199152894b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCellBronchial-NucSeq-Stromal-Fibroblastic-Fibro_peribronchial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

A2M SYNPO2 ECM1 ROBO2 LTBP2 ADGRL2 CDH11 ADAMTSL2

4.49e-072001528fb53be20392a8309a7393774c774a1b1aec6e676
ToppCellPND01-03-samps-Mesenchymal-Matrix_fibroblast-matrix_-_mature_3|PND01-03-samps / Age Group, Lineage, Cell class and subclass

SYNPO2 RNF25 VARS2 PRAG1 SH2D5 THOC6 ATOH1

4.66e-0713715279bfdbc102cdd861996b3c4eac35b606be8af97eb
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ERBB4 MGLL PRAG1 TFCP2L1 SUOX KCNJ2 ROBO2

6.83e-071451527b961b69befb15ff6f58635e0d4bda88ea732a346
ToppCellControl-Myeloid-MoAM2,_CCL18|Control / Condition, Lineage and Cell class

A2M SLC36A1 ZNF618 DYSF ECM1 NRP2 LTBP2

2.31e-0617415274c64ff5666812fb4efa440ba4faeca51d916d68e
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MAGI2 FAT1 IGSF9 WDFY3 CDH2 ADGRL3 SMAD9

2.50e-061761527327a3e81b724252e36d786de92a3ffd721ea6d7b
ToppCellControl-Myeloid-MoAM2,_CCL18|Myeloid / Condition, Lineage and Cell class

A2M SLC36A1 ZNF618 DYSF ECM1 NRP2 LTBP2

2.59e-061771527470f54fe2b21c7350ea471e02039461a3808f700
ToppCell5'-Adult-SmallIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

A2M MAGI2 COL18A1 GREB1 ADGRL2 CDH11 ADGRL3

2.90e-061801527f2f6e83127a4a415e65c76a35efa8175fbd5b5d9
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ERBB4 ETV4 MGLL IQCN PRAG1 LRP1B TFCP2L1

3.12e-061821527a8cc56f32efe180e8fb5d69dbe606a794b3db700
ToppCellAT1-AT2_cells-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

VEPH1 IQCN PTPN21 CDKL5 COL18A1 CGNL1 SMAD9

3.23e-0618315276821dca076318115d360ff426eb1218cfe104063
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

A2M TMPRSS15 ANO5 LRP1B FREM2 FAT1 ADGRL3

3.35e-0618415272cbed6462fea2622871bb7e49b0df3d984239281
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ERBB4 ETV4 MGLL LRP1B TFCP2L1 ROBO2 CGNL1

3.35e-061841527d33de57876817050b294f2ecb0a4eb0634cfa7f0
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

A2M TMPRSS15 ANO5 LRP1B FREM2 FAT1 ADGRL3

3.35e-061841527ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

A2M TMPRSS15 ANO5 LRP1B FREM2 FAT1 ADGRL3

3.35e-0618415272b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell3'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

A2M CHST1 CCDC88C GDPD5 TFCP2L1 KCNJ2 CDH5

3.47e-061851527602536a3308a848f106adcb0a83530997440c8f4
ToppCellMild_COVID-19-Epithelial-AT1/AT2|Mild_COVID-19 / Disease group,lineage and cell class (2021.01.30)

ERBB4 FREM2 TFCP2L1 FAT1 LTBP2 CGNL1 CDH2

3.47e-061851527c55fdba1e3818ec0404d7ab473bf18dd25f2bb0a
ToppCelltumor_Lymph_Node_/_Brain-Endothelial_cells-Tumor_ECs|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

A2M CPXM2 CHST1 COL18A1 ADGRL2 CDH5 ADAMTSL2

3.73e-061871527be5f8c5802b0fa8cc1e274fdf06b13eb8ceb8ad4
ToppCellChildren_(3_yrs)-Endothelial-capillary_endothelial_cell_(Cap1)|Children_(3_yrs) / Lineage, Cell type, age group and donor

A2M DYSF SOX13 NFIB ADGRL2 CDH5 ADGRL3

4.74e-06194152771ac69cdf7a08ca3ddfb5b492b14ac56b6cd5e5d
ToppCellCOVID-19-Fibroblasts-Alveolar_FB|COVID-19 / group, cell type (main and fine annotations)

A2M MAGI2 NFIB ROBO2 LTBP2 CDH11 ADGRL3

4.91e-061951527603050beeb33c331d4b2e3fa46cae3f3e0e4bdc7
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SYNPO2 NRP2 HOXD11 LTBP2 CDH11 ADGRL3 ADAMTSL2

5.07e-061961527fa445f4240c521cf04eb2e2f79a5c55fda31209a
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SYNPO2 NRP2 HOXD11 LTBP2 CDH11 ADGRL3 ADAMTSL2

5.07e-061961527802f61e78a9a1030a86c4a980c398a73cd4d1574
ToppCell3'-GW_trimst-1-SmallIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

A2M DYSF CCDC88C GDPD5 KCNJ2 CGNL1 CDH5

5.25e-06197152798e34e8612f111bb667a574de1faaa785d318ca4
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SYNPO2 MGLL PRELID3A ROBO2 LTBP2 GREB1 ADAMTSL2

5.42e-06198152763f7d25201613bd3404c28fb936954190bca91d3
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SYNPO2 MGLL PRELID3A ROBO2 LTBP2 GREB1 ADAMTSL2

5.42e-061981527a73534b6ca202c277a70a52281d5b97a3e6cb8ef
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Endothelial-Endothelial_immature-Tip-like-A|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

A2M CHST1 DYSF COL18A1 ADGRL2 CDH5 ADAMTSL2

5.42e-06198152772e8b9cccb7b0a2ea9d415218fff4fa2f09728f4
ToppCelltumor_Lung-Endothelial_cells-Tumor_ECs|tumor_Lung / Location, Cell class and cell subclass

A2M CPXM2 DYSF COL18A1 NFIB ADGRL2 CDH5

5.42e-0619815275228c4bf2513186140c2c4eaa67a268c732bdc84
ToppCell5'-Adult-SmallIntestine-Mesenchymal-fibroblastic-Stromal_1_(CCL11+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

A2M SYNPO2 ECM1 COL18A1 ADGRL2 CDH11 ADGRL3

5.42e-0619815277582ee9ec8a87ecb094201f1f9191b412f9d2875
ToppCellParenchymal-NucSeq-Epithelial-Epi_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ERBB4 VEPH1 MGLL CDKL5 FREM2 CGNL1 SCAI

5.61e-0619915278587bd98de7767a575088afbea07a1feb4516b9b
ToppCellParenchymal-NucSeq-Epithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ARHGAP32 ERBB4 VEPH1 CDKL5 FREM2 CGNL1 SCAI

5.61e-0619915275cea0d9e261903e0eaad60c28a07dff72ce65027
ToppCelltumor_Lymph_Node_/_Brain-Fibroblasts|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

A2M CPXM2 ECM1 COL18A1 ROBO2 LTBP2 CDH11

5.79e-0620015274f7e26b27bd51c32420ed8c2f52d070aee542159
ToppCellCOVID-19-Myeloid-MoAM2,_CCL18|COVID-19 / Condition, Lineage and Cell class

A2M LST1 MGLL NIBAN2 ECM1 NRP2 TPP1

5.79e-062001527b0a50622d00335843efad86bc56a1e910019984b
ToppCellBiopsy_Other_PF-Mesenchymal|Biopsy_Other_PF / Sample group, Lineage and Cell type

A2M SYNPO2 ECM1 COL18A1 ROBO2 LTBP2 CDH11

5.79e-062001527d6fcdd48858b53b5a8d18ae14b2dc4d9af41b070
ToppCellE18.5-samps-Mesenchymal-Myofibroblast-myofibroblast_-_mature_-_B|E18.5-samps / Age Group, Lineage, Cell class and subclass

DCAF15 ARMC12 ECM1 SUOX GZMM GREB1

7.69e-061371526b553958e7e6dcd887d860e34d3983cbb85cefaa6
ToppCellPBMC-Mild-Myeloid-Neutrophil-immature_Neutrophil-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

PKD1L1 ECM1 MKI67 TMEM131L ADGRL2 CDH5

9.44e-061421526e160f35b3c18e77c4107fe96db5f56227c91785e
ToppCellwk_15-18-Mesenchymal-Myofibro_&_SMC-Myofibro_2|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

PRAG1 FAT1 NFIB ROBO2 LTBP2 ADAMTSL2

1.67e-051571526b9d04ee417c0d8ea0801d10f1c54e138587009fd
ToppCellControl-Endothelial_cells-Inflamed_endothelial_cells|Control / group, cell type (main and fine annotations)

PKD1L1 CHST1 DYSF NFIB ADGRL2 CDH5

1.86e-051601526958256e3d3836160763b82bb48f794087918d935
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ERBB4 MGLL IQCN PRAG1 LRP1B TFCP2L1

2.00e-051621526373513f9d0e5007b2e10a8b78d4909dcce9e3b62
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_bronchial_vessel|Children_(3_yrs) / Lineage, Cell type, age group and donor

A2M DYSF NFIB ADGRL2 CDH5 ADGRL3

2.07e-051631526977a970b1296234c22178420294cea73506ee02f
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_bronchial_vessel-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

A2M CHST1 NFIB ADGRL2 CDH5 ADGRL3

2.07e-051631526ba7d02db0f0e2f9916ec8db52c067c87b6917c23
ToppCellTCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-5|TCGA-Ovary / Sample_Type by Project: Shred V9

TBC1D5 RC3H1 INTS3 ATF7IP MBD5 WDTC1

2.29e-05166152632d2eaf8a5d03881bf74d680825af2d5110b082d
ToppCell390C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

HIVEP2 YOD1 ZNF718 ADGRL2 ADGRL3 ADAMTSL2

2.62e-051701526a6fa0cab1fa829ec601fe48306b4c43c83425b04
ToppCell390C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

HIVEP2 YOD1 ZNF718 ADGRL2 ADGRL3 ADAMTSL2

2.62e-051701526b40255eee45eb18b5a297336d7f3845fd8f8aa3b
ToppCellCOVID-19_Mild-PLT_2|COVID-19_Mild / Disease Group and Platelet Clusters

DNHD1 RNF25 INTS3 THAP7 TFCP2L1 MTO1

2.89e-051731526d11705e56b6b21eec963ea224717f27680c781ed
ToppCellPND07-Immune-Immune_Myeloid-DC-cDC1-cDC1_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SLC36A1 TBC1D5 ZBTB41 PRDM4 LIN9 HYLS1

2.89e-05173152628c98a9a54aa2cfa67464db4f628c9357ad185b9
ToppCell5'-Adult-Appendix-Mesenchymal-fibroblastic-Stromal_1_(CCL11+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

A2M COL18A1 GREB1 ADGRL2 CDH11 ADGRL3

2.98e-051741526f90ca117b729436cf452e2ddcec26ba525c5c13b
ToppCellBAL-Mild-Myeloid-MoAM-MoAM4-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

SLC36A1 RIPK2 MGLL DYSF NRP2 DNAJB5

2.98e-051741526fe105550a43b935affc73e32796115d20328a2f8
ToppCellBAL-Mild-Myeloid-MoAM-MoAM4|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

SLC36A1 RIPK2 MGLL DYSF NRP2 DNAJB5

2.98e-0517415269191f6abb37ca65da5105f91e21689d11ec1059b
ToppCellBAL-Mild-Myeloid-MoAM-MoAM4|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SLC36A1 RIPK2 MGLL DYSF NRP2 DNAJB5

3.08e-051751526b2099b4ab1bf74497f454a99fffe5f5561b1f968
ToppCellBAL-Mild-Myeloid-MoAM-MoAM4-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SLC36A1 RIPK2 MGLL DYSF NRP2 DNAJB5

3.08e-0517515266e54b74c735f249c7bfab7087c1638065ec1dd2e
ToppCellLPS-IL1RA+antiTNF|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ZNF618 NFIB TMEM131L CGNL1 MBD5 GAB1

3.28e-051771526b7fee75de7e96924af488a5baa2334711889ae7c
ToppCellNS-moderate-d_07-13-Epithelial-Ionocyte|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

VEPH1 PTPN21 ENAM TFCP2L1 LTBP2 SMAD9

3.28e-05177152699500aed584f793aaf308f8afbf5d1c6a9b4ee55
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ERBB4 CPXM2 COL18A1 TFCP2L1 LTBP2 ADGRL2

3.28e-051771526c9e8149639551a4c8daa90fcb2b895fdcff2e2ba
ToppCell5'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-Mature_venous_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DYSF MAP3K3 UBE2T MKI67 CDH5 ARHGAP33

3.39e-051781526ea10117026021c959ffc871fc377cdb3e161d264
ToppCellCOPD-Epithelial-PNEC|Epithelial / Disease state, Lineage and Cell class

ANO5 DLK1 CHST1 GREB1 CDH2 SEZ6L

3.50e-051791526988d0853c391da1e5004f73f3678047418d3f6d3
ToppCellLV|World / Chamber and Cluster_Paper

SYNPO2 ANO5 KCNJ2 ADGRL2 CDH2 GAB1

3.61e-0518015265ac6f485a58bb29462fec02dfbe8eb70864eafe3
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ETV4 NFIB ROBO2 CGNL1 CDH11 SEZ6L

3.61e-051801526e8841ef1239f9ee73ac4f4e11faca0742694f368
ToppCellfacs-Pancreas-Exocrine|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

B4GALNT1 MGLL GDPD5 COL18A1 NFIB CGNL1

3.84e-05182152645faefd7cbeac84d2c58650530b902af6ce921f8
ToppCelltumor_Lymph_Node_/_Brain-Endothelial_cells|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

A2M CPXM2 COL18A1 ADGRL2 CDH5 ADAMTSL2

3.84e-051821526d7cce5dd7046f06bf40f00c9dbfa610722b03333
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ETV4 NFIB ROBO2 CGNL1 CDH11 SEZ6L

3.84e-05182152605c167158815bf25d509df59ab386e1990712765
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MAGI2 FAT1 WDFY3 CDH2 ADGRL3 SMAD9

3.95e-051831526738e94b50c4c08c727d4eed0708dda08aa6891b4
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

VEPH1 CCDC88C TFCP2L1 PRR35 APCDD1L ROBO2

3.95e-051831526b5ede5a0048c585b73c00e88aeddbcaf669347b1
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MAGI2 FAT1 WDFY3 CDH2 ADGRL3 SMAD9

3.95e-05183152692fbd83a9d13ee91065cbd479fb298f1fd564568
ToppCellwk_20-22-Mesenchymal-Myofibro_&_SMC-Myofibro_3|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

PRAG1 FAT1 NFIB ROBO2 CDH11 ADAMTSL2

3.95e-051831526f4ea7113ce9099222743d9ff02388d3d8a9e987b
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ERBB4 ETV4 MGLL LRP1B TFCP2L1 ROBO2

4.08e-0518415268fd8bd3d28d0ee6f0ef1f14e354d8eaf63a8081b
ToppCellMild_COVID-19-Myeloid-MoAM4|Mild_COVID-19 / Disease group,lineage and cell class (2021.01.30)

SLC36A1 RIPK2 MGLL DYSF NRP2 DNAJB5

4.08e-05184152663ef6ba6ac33c3032735008ce3b411636ab3c395
ToppCellPericytes-Donor_07|World / lung cells shred on cell class, cell subclass, sample id

A2M SYNPO2 CHST1 COL18A1 ADGRL3 ADAMTSL2

4.08e-0518415263d2d55d0f22874be21665ab37da710482f77fc36
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Myeloid-Dendritic|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

LST1 UBE2L6 LASP1 TPP1 EIF2AK4 SEZ6L

4.20e-051851526405bd4ba7ca7f7b625c49f1313ff946509e17c13
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

COLGALT2 NRP2 NFIB ROBO2 LTBP2 CDH11

4.20e-0518515269f19f04fc4d97dfc2dd78cde77b515f1cb5d51ec
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Myeloid-Dendritic-conventional_dendritic_cell|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

LST1 UBE2L6 LASP1 TPP1 EIF2AK4 SEZ6L

4.20e-0518515262aa5e9f6f167d27317a01d22392b59512333fa64
ToppCell5'-Parenchyma_lung-Epithelial-Neuro-endocrine/ionocytic-lung_neuroendocrine_cell-Neuroendocrine|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ARMC12 ANO5 DLK1 GREB1 CDH2 SEZ6L

4.33e-0518615262fab7abed16a894afdd0207e86fc43a25a77fb9e
ToppCell5'-Parenchyma_lung-Epithelial-Neuro-endocrine/ionocytic-lung_neuroendocrine_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ARMC12 ANO5 DLK1 GREB1 CDH2 SEZ6L

4.33e-051861526ea2c8e0df038a00062d2098b4a9ac85141b9a728
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FREM2 FAT1 IGSF9 WDFY3 CDH2 ADGRL3

4.33e-0518615265c4ffe4e4d5536ae9f8794277fe032c693e7dd56
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-6_LAMP5_CA13_(Lamp5_Lhx6_1)|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ERBB4 SOX13 NRP2 COL18A1 FREM2 FAT1

4.33e-05186152677592a6397b44b2b59a4fc39d7224dd95343efe6
ToppCellTCGA-Kidney-Primary_Tumor-Renal_Cell_Carcinoma-Kidney_Clear_Cell_Renal_Carcinoma-2|TCGA-Kidney / Sample_Type by Project: Shred V9

SYNPO2 B4GALNT1 CHST1 KCNJ2 LTBP2 CDH11

4.33e-0518615261e6526fc9e9381b7ace864588cc7bd80194338d6
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(CH25H+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MGLL CHST1 ECM1 HOXD11 DDHD1 ADGRL3

4.33e-051861526360c3e9e5c3a943e68e6939b4a47821bfc75b553
ToppCell5'-Parenchyma_lung-Epithelial-Neuro-endocrine/ionocytic-lung_neuroendocrine_cell-Neuroendocrine-Neuroendocrine_L.0.7.2.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ARMC12 ANO5 DLK1 GREB1 CDH2 SEZ6L

4.33e-051861526714765585a644bf9817ab6eb3001b43b3c2d2410
ToppCellE16.5-samps-Mesenchymal-Myofibroblast|E16.5-samps / Age Group, Lineage, Cell class and subclass

SYNPO2 PRAG1 MAGI2 ROBO2 LTBP2 ADAMTSL2

4.33e-051861526e044b3428b7eacfdc72d0f57cdabaa1de04c74cd
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ERBB4 MGLL PRAG1 LRP1B TFCP2L1 SMAD3

4.46e-05187152687b3d0478693d4c54ff06b74e5903036b9c1ee6a
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ERBB4 MGLL PRAG1 LRP1B TFCP2L1 SMAD3

4.46e-05187152642a1267bfc27b4460b8409ada580a87c4385841c
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ERBB4 MGLL PRAG1 LRP1B TFCP2L1 SMAD3

4.46e-05187152664afdea159f5e67a1e5cea35ce898aae6e80aea5
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

COLGALT2 NRP2 NFIB ROBO2 LTBP2 CDH11

4.46e-05187152613731298bc562ec29582f5da1b4c97261284f6f1
ToppCellpdx-Tumor_cells-T5|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

NRP2 MAGI2 FREM2 CGNL1 WDFY3 SEZ6L

4.46e-0518715267e376831a11ee72ed87abcdac631ca46ae29c250
ToppCellAdult-Mesenchymal-matrix_fibroblast_1_cell-D175|Adult / Lineage, Cell type, age group and donor

A2M COLGALT2 ROBO2 LTBP2 CDH11 ADAMTSL2

4.46e-051871526e15d2967aac248da3517bc2c7d1beaa1d5a0aa7f
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ERBB4 MGLL LRP1B TFCP2L1 ADGRL2 SMAD3

4.46e-05187152677886f99c229610abd28c4c370d2c7d1536c9782
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ERBB4 CPXM2 LRP1B ADGRL2 GAB1 SMAD3

4.46e-051871526f124d2c699b717b7c02a1a70493f515b83dc2f4c
Diseaseneuroimaging measurement

KMT2B RBBP5 TBC1D5 PTPN21 DYSF SH2D5 NRP2 CCDC88C YOD1 COL18A1 ZNF106 BPGM NFIB ROBO2 IGSF9 CDH11 SCAI

3.01e-05106914917EFO_0004346
Diseaseprostate cancer (is_marker_for)

ERBB4 KMT2B PHLPP1 SMAD3 SMAD9 SOS1

1.46e-041561496DOID:10283 (is_marker_for)
Diseasecortical thickness

A2M B4GALNT1 KMT2B TBC1D5 TM7SF3 DYSF NRP2 STAU1 COL18A1 ZNF106 BPGM ROBO2 IGSF9 ATOH1 SGF29 CDH11

1.68e-04111314916EFO_0004840
Diseaseadverse effect, response to xenobiotic stimulus

LRP1B SOX13 MAGI2 NFIB

2.29e-04591494EFO_0009658, GO_0009410
DiseaseGeleophysic dysplasia

SMAD2 ADAMTSL2

2.51e-0451492C3489726
DiseaseAcromicric Dysplasia

SMAD2 ADAMTSL2

2.51e-0451492C0265287
Diseaseattention deficit hyperactivity disorder (implicated_via_orthology)

ADGRL2 CDH2 ADGRL3

3.77e-04281493DOID:1094 (implicated_via_orthology)
Diseaseplatelet component distribution width

HIVEP2 TBC1D5 DLK1 SIN3A LIN9 DCAF5 COL18A1 DDHD1 ATAD2B TMEM131L EIF2AK4 GAA

4.70e-0475514912EFO_0007984
Diseasebirth measurement, spontaneous preterm birth

ADGRL2 SMAD9

5.23e-0471492EFO_0006917, EFO_0006921
DiseaseCerebral ventriculomegaly

SIN3A CCDC88C

5.23e-0471492C1531647
DiseaseHydrocephalus Ex-Vacuo

SIN3A CCDC88C

5.23e-0471492C0270720
DiseaseLoeys-Dietz Syndrome

SMAD2 SMAD3

5.23e-0471492C2697932
Diseasemyoclonic-atonic epilepsy (implicated_via_orthology)

VARS2 ROBO2

5.23e-0471492DOID:0060475 (implicated_via_orthology)
DiseaseCommunicating Hydrocephalus

SIN3A CCDC88C

5.23e-0471492C0009451
DiseaseFetal Cerebral Ventriculomegaly

SIN3A CCDC88C

5.23e-0471492C2936718
Diseaselimb-girdle muscular dystrophy (implicated_via_orthology)

DYSF FER1L5

5.23e-0471492DOID:11724 (implicated_via_orthology)
DiseasePost-Traumatic Hydrocephalus

SIN3A CCDC88C

5.23e-0471492C0477432
DiseaseObstructive Hydrocephalus

SIN3A CCDC88C

5.23e-0471492C0549423
Diseasemean platelet volume

ARHGAP32 HIVEP2 RBBP5 TBC1D5 TM7SF3 DLK1 SIN3A SIK3 LIN9 DCAF5 DDHD1 ATAD2B KCTD20 TMEM131L

6.86e-04102014914EFO_0004584
DiseaseFamilial pulmonary arterial hypertension

EIF2AK4 SMAD9

6.95e-0481492C1701939
DiseaseCongenital Hydrocephalus

SIN3A CCDC88C

6.95e-0481492C0020256
DiseaseAqueductal Stenosis

SIN3A CCDC88C

6.95e-0481492C2936786
DiseaseIdiopathic pulmonary hypertension

EIF2AK4 SMAD9

8.91e-0491492C0152171
DiseaseHydrocephalus

SIN3A CCDC88C

8.91e-0491492C0020255
DiseasePulmonary arterial hypertension

EIF2AK4 SMAD9

1.11e-03101492C2973725
Diseasehemopexin measurement

ZBTB41 LHX9

1.35e-03111492EFO_0008149
DiseaseCopper-Overload Cirrhosis

MKI67 SMAD2

1.35e-03111492C1876165
Diseasedyslexia

TBC1D5 RC3H1 PTPN21 NFIB ADGRL2

1.42e-031621495EFO_0005424
DiseaseMale sterility

HOXD11 DROSHA MTRR

1.85e-03481493C0917731
DiseaseMale infertility

HOXD11 DROSHA MTRR

1.85e-03481493C0021364
DiseaseSubfertility, Male

HOXD11 DROSHA MTRR

1.85e-03481493C0848676
Diseasejuvenile polyposis syndrome (implicated_via_orthology)

HIVEP2 SMAD9

1.90e-03131492DOID:0050787 (implicated_via_orthology)
Diseasehepatocellular carcinoma (implicated_via_orthology)

CAD COL18A1 SMAD2

1.96e-03491493DOID:684 (implicated_via_orthology)
Diseasecardiac troponin I measurement

SYNPO2 ANO5 GREB1 ATOH1 GAB1

2.04e-031761495EFO_0010071
Disease2-oxo-hept-3-ene-1,7-dioate hydratase activity

EIF2AK4 SMAD9

2.21e-03141492C1150929
Diseasephoneme awareness

ZNFX1 STAU1

2.21e-03141492EFO_0021812
DiseaseAutosomal recessive limb-girdle muscular dystrophy

ANO5 DYSF

2.21e-03141492cv:C2931907
DiseaseFamilial thoracic aortic aneurysm and aortic dissection

COL18A1 SMAD2 SMAD3

2.46e-03531493C4707243
Diseaseattention deficit hyperactivity disorder, substance abuse, antisocial behaviour measurement

ERBB4 CPXM2 TBC1D5 MAGI2 NFIB HELZ ROBO2 ADGRL2 C2orf49 ADGRL3 SCAI

2.57e-0380114911EFO_0003888, EFO_0007052, MONDO_0002491
Diseasevision disorder

ANO5 MAGI2

2.90e-03161492MONDO_0021084
DiseaseIdiopathic pulmonary arterial hypertension

EIF2AK4 SMAD9

2.90e-03161492C3203102
DiseaseColorectal Neoplasms

FAT1 MKI67 MTRR CDH5 SMAD3 SMAD9

2.91e-032771496C0009404
DiseaseColorectal Carcinoma

CAD ADAM29 CDKL5 FAT1 MKI67 MTRR CDH5 SMAD2 SMAD3 SMAD9

3.09e-0370214910C0009402
Diseasevisceral adipose tissue measurement

ERBB4 HIVEP2 RIPK2 DLK1 IQCN MAGI2 HELZ ROBO2

3.17e-034811498EFO_0004765
DiseaseFamilial primary pulmonary hypertension

EIF2AK4 SMAD9

3.28e-03171492C0340543
Diseasegraft-versus-host disease (is_implicated_in)

LST1 MKI67

3.28e-03171492DOID:0081267 (is_implicated_in)
Diseasecaudal anterior cingulate cortex volume measurement

TMPRSS15 FAT2

3.28e-03171492EFO_0010289
Diseaseage at menarche

ERBB4 TBC1D5 DLK1 CHST1 LRP1B MAGI2 GREB1 ADGRL2 SMAD2

3.31e-035941499EFO_0004703
Diseasecolorectal cancer (is_implicated_in)

ERBB4 LRP1B FAT1 MKI67

3.36e-031211494DOID:9256 (is_implicated_in)
Diseasecerebral infarction (is_marker_for)

A2M SOS1

4.09e-03191492DOID:3526 (is_marker_for)
Diseaseinferior parietal cortex volume measurement

CPXM2 GREB1

4.09e-03191492EFO_0010307
Diseasehousehold income

ERBB4 LRP1B SUOX NFIB ATF7IP CDH2

4.57e-033041496EFO_0009695
Diseasekeratoconus

LRP1B ZNF106 SMAD3

4.58e-03661493MONDO_0015486
Diseaseretinal vasculature measurement

ERBB4 SLC36A1 NIBAN2 DYSF PRAG1 ZNF106 LTBP2 SMAD2

4.88e-035171498EFO_0010554
DiseaseLeft Ventricle Remodeling

SMAD2 SMAD3

4.99e-03211492C0600520
DiseaseVentricular Remodeling

SMAD2 SMAD3

4.99e-03211492C0600519

Protein segments in the cluster

PeptideGeneStartEntry
QYHSPPDVVIPVRIT

ADAM29

26

Q9UKF5
DLYVQHAIPLPQRDL

C2orf49

51

Q9BVC5
SLPPRSTLQHPDYLQ

ERBB4

1246

Q15303
YPRRKVQDPPVVHEL

DNAJB5

161

O75953
TIQEGSREQPYHPPD

EIF2D

366

P41214
QYLNVPPSPKVEDRH

ANKRD34C

166

P0C6C1
SEPPNPTNERYTLHQ

ANO5

261

Q75V66
HTPLYERSLPINPAQ

C9orf129

76

Q5T035
GRDEPPESYPQRQDH

EIF2AK4

11

Q9P2K8
PEPRYAHIPVRIKEQ

B4GALNT1

56

Q00973
AIQHPRYKPVPALEN

GZMM

96

P51124
PLLPPRVYSTENHQP

ADGRL3

1306

Q9HAR2
QPQPRASPRLVEELY

APCDD1L

206

Q8NCL9
PLIPQRTHSLLYQPQ

ADGRL2

1326

O95490
TLIVEPHVIPNRGPY

AQR

776

O60306
NFILHVPYEPPASER

DNHD1

1171

Q96M86
APQLPVDPHRDTILN

DHX30

431

Q7L2E3
YRLTPGVHELPVQQP

DLK1

266

P80370
RPSLYAQVQKPPRHA

CDH5

681

P33151
LQRVPRNYDPALHPF

DCAF13

21

Q9NV06
RNYDPALHPFEVPRE

DCAF13

26

Q9NV06
KIIYEPHPQLTRNLP

ATG2B

261

Q96BY7
NLPLPDYVHPQLRRV

ARMC12

176

Q5T9G4
HPLNELIPLVYIQDP

A2M

156

P01023
NVPRKVPNHYIAIPE

CPXM2

471

Q8N436
GREPLPAPYQHQLSE

ETV4

201

P43268
IEGRVAIHYINPPNP

RAE1

236

P78406
VAPHPTQIRPSYLRE

RC3H1

721

Q5TC82
TIRYPPHLNPQDTLK

NFIB

386

O00712
PQHLPRGLYPTEEIQ

QRICH2

1571

Q9H0J4
QLLEVPDPNVVPHYA

RFT1

106

Q96AA3
IIPNFYPPLEGHVRQ

INTS3

441

Q68E01
VRFQHPEENRLLSPP

IQCN

171

Q9H0B3
RNHVQPYIPSILEAL

NIBAN2

336

Q96TA1
IHYDPLQRNFPDPDT

YOD1

266

Q5VVQ6
IDLHNQASVPLEPRP

KCNJ2

406

P63252
NPINEPLFYHILNPD

FAT1

2006

Q14517
AQPFDLQIYHPSRQP

LRP1B

1511

Q9NZR2
LHYTPPLQSPIIDND

LIN9

301

Q5TKA1
QPPLLDYRQHSPDTR

MAGI2

1116

Q86UL8
HLTEIRQYQQAPPQP

GREB1

471

Q4ZG55
PQSIPYQDLPHLVNA

MGLL

11

Q99685
PHNLTYPLGPRNEDL

KCTD20

41

Q7Z5Y7
PEDQLPCYLTHTNPR

MTO1

276

Q9Y2Z2
PYQLINVPPHLETLG

GAB1

161

Q13480
TVDRYQAPPIVPAHQ

ATAD2B

291

Q9ULI0
NIPGLPPEYLQVHLQ

MTRR

241

Q9UBK8
PRLIDEIVINPHYNR

TMPRSS15

856

P98073
YLHPVDNQPPEILNT

FREM2

821

Q5SZK8
SYRRPLEQQQPHHIP

LASP1

151

Q14847
ERDYLQAQHPPSPIK

CCDC88C

216

Q9P219
EHRPQFPQDPYSTRV

FAT2

3316

Q9NYQ8
ADHLDRDQQPYPPSQ

LHX9

251

Q9NQ69
QPPVVQLHDSNPYPR

COL18A1

1506

P39060
PPGYIPDELHQVARN

MAP3K2

166

Q9Y2U5
PAVYEKQPQPINRHL

VEPH1

186

Q14D04
EGQYARLISPPVHLP

NRP2

696

O60462
PPVLYDIHSRLPVFQ

DCAF5

256

Q96JK2
DLEQAPPPHRTYLTV

MYOCOS

51

A0A1B0GUC4
FEYTLLQPPHESRPQ

ADAMTSL2

326

Q86TH1
EYSNPAPLPLDQHSR

LPXN

21

O60711
TYLNREPQLKAPTPH

GABRA1

441

P14867
DPPREHPYRSSFINV

GDPD5

361

Q8WTR4
VLPNAVLPPSLDHVY

KMT2B

1526

Q9UMN6
HLRPELFDENLPPNT

MKI67

511

P46013
RRSYNVTPPPIEESH

BPGM

116

P07738
YRVQEPAVHIPGQEP

PABPC1L

516

Q4VXU2
IQQLPPPHYRTLEFL

ARHGAP32

486

A7KAX9
LHPYVEAGNPQARPL

HELZ

711

P42694
FPSPILKVQYHPRDQ

RBBP5

106

Q15291
YSQPEIREHAQLPSP

PTPN21

491

Q16825
HQALEQAVRPPDAPL

PRR35

451

P0CG20
HDVIQQLPPPHYRTL

ARHGAP33

426

O14559
PNYLPIRQDTHPPSV

GIG44

56

P09565
RPALPVQLQYPHVES

HYLS1

61

Q96M11
QRHPELLQPYDPEKN

CGNL1

146

Q0VF96
DLQIYPQERHSIRVP

DPP8

856

Q6V1X1
PYSSNLAPHVQPVRE

HOXD11

46

P31277
QPPATLQAREHPVYP

ATOH1

36

Q92858
LPPEIIHNPNFTVRD

CDH11

531

P55287
LPVPRAPANHQVVYT

ATF7IP

1051

Q6VMQ6
PANRRYEVPLETPHV

GAA

186

P10253
ESPLQPSELQPHYVA

LTBP2

1706

Q14767
LPGSQQQELHPVYPR

MBD5

186

Q9P267
YANPAVVRPHAQIPQ

CSN3

81

P07498
VVRPHAQIPQRQYLP

CSN3

86

P07498
QEEAPQPHYQLRACP

ECM1

271

Q16610
IRENHPYPNIRNFPS

ENAM

316

Q9NRM1
NIFHPTDPVAYRLEP

DDHD1

656

Q8NEL9
YLPIPLKPHQTLQED

COLGALT2

291

Q8IYK4
APKENRHLYNDPVPR

CDKL5

696

O76039
VPEHVESRPLYSPLQ

DYSF

1761

O75923
YPPTQHPPVAILARN

PKD1L1

271

Q8TDX9
ERPIHAEPQYPVRSA

CDH2

811

P19022
NHRDIYVSTVAVPPP

DCAF15

176

Q66K64
INTIYQPPEPRSRHL

MAP3K3

151

Q99759
LADRPPPQYIHPNSI

PRDM4

116

Q9UKN5
EQELHYASLQRLPVP

LST1

51

O00453
EADRQYDIPPQHRLP

MINAR1

766

Q9UPX6
GQPLPLITDYAVQPH

VARS2

371

Q5ST30
YPLHPLQLQEPNTDR

DROSHA

1081

Q9NRR4
TSQPYVAHTLPQRPE

SEZ6L

206

Q9BYH1
NSPQYHQPDLPEISR

TMEM131L

1121

A2VDJ0
QSEPNQYPTLHPPLR

FER1L5

1921

A0AVI2
DHPIPQYEVNPRTTE

HAUS1

21

Q96CS2
YLLQHPEERAQPEPC

SH2D5

146

Q6ZV89
VNERLVYTPHPENPE

PRELID3A

106

Q96N28
PGLPQSILHPQDVAY

SIMC1

271

Q8NDZ2
HRVLAPAPPVYEAVS

SIN3A

31

Q96ST3
LLSPTPPDYTRHQQV

SIK3

951

Q9Y2K2
PPDYTRHQQVPHILQ

SIK3

956

Q9Y2K2
QHPALIPVLRPYQRE

SHPRH

296

Q149N8
LSPENEARLPPLQYV

TFCP2L1

36

Q9NZI6
RHPTPLQQEPRKISY

SOS1

1051

Q07889
PVLVPRHSEYNPQLS

SMAD9

141

O15198
LRLPPPAGAYIQNEH

THAP7

216

Q9BT49
ENYIKPPPVNHTTDR

CHST1

136

O43916
LEERPHLPSTFNYNP

CNOT2

521

Q9NZN8
TEEPDVHLPQPYAVA

TPRA1

301

Q86W33
HVSPQVELPPYLERV

WDTC1

351

Q8N5D0
QPLVEHYVPRSLDPN

SOX13

556

Q9UN79
EPYNLKIHETAARPP

ZNF718

61

Q3SXZ3
KVQPPSHARYPSQLD

USP6NL

606

Q92738
QQKLRPVPPYQHEEI

ZNF618

811

Q5T7W0
HPHPNPIEVRNYSRL

WDFY3

3366

Q8IZQ1
NVRAPPPVAYNPIHS

SYNPO2

916

Q9UMS6
YQFIVQRIPDPSHLP

SLC36A1

236

Q7Z2H8
PPVLIAQPDHSYNLA

SEC16A

826

O15027
VPHGPLTRPSEQLDY

STAU1

481

O95793
RALIHAPPQRPQDDY

SGF29

246

Q96ES7
HYQRVETPVLPPVLV

SMAD2

166

Q15796
HYQRVETPVLPPVLV

SMAD3

126

P84022
HRPVINEESLPYDIP

RIPK2

246

O43353
LVLQVPAEYPHEVPQ

RNF25

66

Q96BH1
PAEYPHEVPQISIRN

RNF25

71

Q96BH1
LQPPPVTTEQHGARY

TAPBP

366

O15533
HEILSPQPQSTDYPR

ZBTB41

836

Q5SVQ8
QQITHTSPRIQPDYP

SAP130

436

Q9H0E3
PDQPPYHLKAFNLRI

UBE2L6

41

O14933
PQIRFLTPIYHPNID

UBE2T

66

Q9NPD8
RQPPYRTSLEVPEIN

THOC6

116

Q86W42
SYPQLPRDETVENPH

SCAI

566

Q8N9R8
PPLPVQTYLHQGLED

ROBO2

1106

Q9HCK4
ARLPAYRQPVPHPEQ

IGSF9

1161

Q9P2J2
AHPREATQPEPIYAE

PRAG1

401

Q86YV5
PRRIFHLPPQEDTYV

CAD

1736

P27708
EPIPDIRNQYPEHIS

ZNFX1

231

Q9P2E3
EPPERLLYPHTSQEA

ZNF862

1151

O60290
LQPQLPRHYQLDQLP

PHLPP1

1696

O60346
PDPHQEYLDPRITIA

SPZ1

21

Q9BXG8
TRNHLPVPNLDPDTY

SUOX

216

P51687
PVPNLDPDTYRLHVV

SUOX

221

P51687
RNPRPVTYQFHPNLD

TBC1D5

416

Q92609
SPPRPNHYLLIDTQG

ZNF581

46

Q9P0T4
VQQVAEKQYPPHRPS

HIVEP2

76

P31629
LQETYEPSEHPDQVP

ZNF106

1116

Q9H2Y7
RRVTNILDPSYHIPP

TM7SF3

526

Q9NS93
VRSPHPYQLPQALAP

TPP1

151

O14773
PFQEYVEQLLHPQDP

JMJD8

111

Q96S16