Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiontransporter activity

SLCO1B7 SLC6A2 TIMM17B SLC22A9 SLC22A25 SLC38A10 CNNM2 SLC4A7 SLC18A2 SV2B SV2A SLC22A11 SLC6A20 SLC22A15 APOF SLC5A7 SLC4A10 SLC16A11 CLDN4 SLC1A7 SLC2A3 ABCB1 ABCB4

2.71e-1212896323GO:0005215
GeneOntologyMolecularFunctiontransmembrane transporter activity

SLCO1B7 SLC6A2 TIMM17B SLC22A9 SLC22A25 SLC38A10 CNNM2 SLC4A7 SLC18A2 SV2B SV2A SLC22A11 SLC6A20 SLC22A15 SLC5A7 SLC4A10 SLC16A11 CLDN4 SLC1A7 SLC2A3 ABCB1 ABCB4

3.98e-1211806322GO:0022857
GeneOntologyMolecularFunctionorganic anion transmembrane transporter activity

SLCO1B7 SLC22A9 SLC22A25 SLC38A10 SLC4A7 SLC22A11 SLC6A20 SLC4A10 SLC16A11 SLC1A7 SLC2A3 ABCB1

1.09e-102936312GO:0008514
GeneOntologyMolecularFunctionsecondary active transmembrane transporter activity

SLCO1B7 SLC6A2 SLC22A9 SLC22A25 SLC4A7 SLC18A2 SLC22A11 SLC6A20 SLC5A7 SLC4A10 SLC16A11 SLC1A7

1.23e-102966312GO:0015291
GeneOntologyMolecularFunctionactive transmembrane transporter activity

SLCO1B7 SLC6A2 SLC22A9 SLC22A25 SLC4A7 SLC18A2 SLC22A11 SLC6A20 SLC5A7 SLC4A10 SLC16A11 SLC1A7 ABCB1 ABCB4

2.09e-104776314GO:0022804
GeneOntologyMolecularFunctionsolute:sodium symporter activity

SLC6A2 SLC4A7 SLC18A2 SLC6A20 SLC5A7 SLC4A10 SLC1A7

6.39e-0981637GO:0015370
GeneOntologyMolecularFunctionsymporter activity

SLC6A2 SLC4A7 SLC18A2 SLC6A20 SLC5A7 SLC4A10 SLC16A11 SLC1A7

2.30e-08150638GO:0015293
GeneOntologyMolecularFunctionsolute:monoatomic cation symporter activity

SLC6A2 SLC4A7 SLC18A2 SLC6A20 SLC5A7 SLC4A10 SLC1A7

9.38e-08119637GO:0015294
GeneOntologyMolecularFunctionsodium-independent organic anion transmembrane transporter activity

SLCO1B7 SLC22A9 SLC22A25 SLC22A11

2.66e-0718634GO:0015347
GeneOntologyMolecularFunctioncarboxylic acid transmembrane transporter activity

SLCO1B7 SLC22A9 SLC22A25 SLC38A10 SLC6A20 SLC16A11 SLC1A7 ABCB1

2.77e-07207638GO:0046943
GeneOntologyMolecularFunctionorganic acid transmembrane transporter activity

SLCO1B7 SLC22A9 SLC22A25 SLC38A10 SLC6A20 SLC16A11 SLC1A7 ABCB1

2.87e-07208638GO:0005342
GeneOntologyMolecularFunctioninorganic anion transmembrane transporter activity

SLC6A2 SLC4A7 SLC18A2 SLC22A11 SLC4A10 CLDN4 SLC1A7

1.10e-06171637GO:0015103
GeneOntologyMolecularFunctionsodium ion transmembrane transporter activity

SLC6A2 SLC4A7 SLC18A2 SLC6A20 SLC5A7 SLC4A10 SLC1A7

1.10e-06171637GO:0015081
GeneOntologyMolecularFunctionlipid transporter activity

SLCO1B7 SLC22A9 SLC22A25 SLC22A11 APOF ABCB1 ABCB4

2.74e-06196637GO:0005319
GeneOntologyMolecularFunctionmonoatomic anion transmembrane transporter activity

SLC6A2 SLC4A7 SLC18A2 SLC4A10 CLDN4 SLC1A7

8.06e-06151636GO:0008509
GeneOntologyMolecularFunctionceramide floppase activity

ABCB1 ABCB4

2.93e-053632GO:0099038
GeneOntologyMolecularFunctionhedgehog receptor activity

PTCH2 PTCH1

2.93e-053632GO:0008158
GeneOntologyMolecularFunctionactive monoatomic ion transmembrane transporter activity

SLC6A2 SLC4A7 SLC18A2 SLC6A20 SLC5A7 SLC4A10 SLC1A7

4.43e-05301637GO:0022853
GeneOntologyMolecularFunctionchloride transmembrane transporter activity

SLC6A2 SLC18A2 SLC4A10 CLDN4 SLC1A7

4.66e-05125635GO:0015108
GeneOntologyMolecularFunctionsphingolipid floppase activity

ABCB1 ABCB4

5.85e-054632GO:0046623
GeneOntologyMolecularFunctionsmoothened binding

PTCH2 PTCH1

5.85e-054632GO:0005119
GeneOntologyMolecularFunctionhedgehog family protein binding

PTCH2 PTCH1

5.85e-054632GO:0097108
GeneOntologyMolecularFunctionamino-acid betaine transmembrane transporter activity

SLC6A20 SLC22A15

5.85e-054632GO:0015199
GeneOntologyMolecularFunctionlipid transmembrane transporter activity

SLCO1B7 SLC22A9 SLC22A25 SLC22A11

8.32e-0573634GO:0170055
GeneOntologyMolecularFunctionshort-chain fatty acid transmembrane transporter activity

SLC22A9 SLC22A25

9.74e-055632GO:0015636
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

SLC6A2 CNNM2 SLC4A7 SLC18A2 SLC6A20 SLC5A7 SLC4A10 SLC1A7

1.03e-04465638GO:0046873
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

SLC6A2 CNNM2 SLC4A7 SLC18A2 SLC22A11 SLC6A20 SLC5A7 SLC4A10 CLDN4 SLC1A7

1.21e-047586310GO:0015318
GeneOntologyMolecularFunctionorganic cation transmembrane transporter activity

SLC6A2 SLC6A20 SLC22A15 SLC5A7

1.37e-0483634GO:0015101
GeneOntologyMolecularFunctionsolute:inorganic anion antiporter activity

SLC4A7 SLC22A11 SLC4A10

1.39e-0432633GO:0005452
GeneOntologyMolecularFunctionsodium:bicarbonate symporter activity

SLC4A7 SLC4A10

1.46e-046632GO:0008510
GeneOntologyMolecularFunctionmonocarboxylic acid transmembrane transporter activity

SLCO1B7 SLC22A9 SLC22A25 SLC16A11

1.88e-0490634GO:0008028
GeneOntologyMolecularFunctionphosphatidylcholine floppase activity

ABCB1 ABCB4

2.71e-048632GO:0090554
GeneOntologyMolecularFunctionendopeptidase regulator activity

SLCO1B7 USP14 WFIKKN2 SERPINA10 PSMD14

4.30e-04201635GO:0061135
GeneOntologyMolecularFunctionmonoamine transmembrane transporter activity

SLC6A2 SLC18A2

6.34e-0412632GO:0008504
GeneOntologyMolecularFunctiontoxin transmembrane transporter activity

SLC22A9 SLC22A25

6.34e-0412632GO:0019534
GeneOntologyMolecularFunctionmonoatomic cation:bicarbonate symporter activity

SLC4A7 SLC4A10

7.47e-0413632GO:0140410
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

SLC6A2 CNNM2 SLC4A7 SLC18A2 SLC6A20 SLC5A7 SLC4A10 SLC1A7

7.64e-04627638GO:0022890
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

SLC6A2 CNNM2 SLC4A7 SLC18A2 SLC6A20 SLC5A7 SLC4A10 CLDN4 SLC1A7

8.12e-04793639GO:0015075
GeneOntologyMolecularFunctionprostaglandin transmembrane transporter activity

SLCO1B7 SLC22A11

8.70e-0414632GO:0015132
GeneOntologyMolecularFunctionantiporter activity

SLC4A7 SLC18A2 SLC22A11 SLC4A10

9.49e-04138634GO:0015297
GeneOntologyMolecularFunctionquaternary ammonium group transmembrane transporter activity

SLC6A20 SLC22A15

1.00e-0315632GO:0015651
GeneOntologyMolecularFunctionicosanoid transmembrane transporter activity

SLCO1B7 SLC22A11

1.00e-0315632GO:0071714
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

SLC6A2 CNNM2 SLC4A7 SLC18A2 SLC6A20 SLC5A7 SLC4A10 SLC1A7

1.11e-03664638GO:0008324
GeneOntologyMolecularFunctionK63-linked deubiquitinase activity

USP14 PSMD14

1.14e-0316632GO:0061578
GeneOntologyMolecularFunctionfloppase activity

ABCB1 ABCB4

1.14e-0316632GO:0140328
GeneOntologyMolecularFunctionsodium:chloride symporter activity

SLC6A2 SLC18A2

1.29e-0317632GO:0015378
GeneOntologyMolecularFunctionpeptidase regulator activity

SLCO1B7 USP14 WFIKKN2 SERPINA10 PSMD14

1.30e-03257635GO:0061134
GeneOntologyMolecularFunctionorganic hydroxy compound transmembrane transporter activity

SLCO1B7 SLC6A2 SLC18A2

1.41e-0370633GO:1901618
GeneOntologyMolecularFunctionL-amino acid transmembrane transporter activity

SLC38A10 SLC6A20 SLC1A7

1.47e-0371633GO:0015179
GeneOntologyMolecularFunctionmonoatomic anion:sodium symporter activity

SLC6A2 SLC18A2

1.62e-0319632GO:0015373
GeneOntologyMolecularFunctionsphingolipid transporter activity

ABCB1 ABCB4

1.79e-0320632GO:0046624
GeneOntologyMolecularFunctionproteasome binding

USP14 PSMD14

1.79e-0320632GO:0070628
GeneOntologyMolecularFunctionfolic acid binding

MTR FTCD

1.79e-0320632GO:0005542
GeneOntologyMolecularFunctionphosphatidylcholine transporter activity

ABCB1 ABCB4

1.79e-0320632GO:0008525
GeneOntologyMolecularFunctionfatty acid transmembrane transporter activity

SLC22A9 SLC22A25

2.37e-0323632GO:0015245
GeneOntologyMolecularFunctionchloride:monoatomic cation symporter activity

SLC6A2 SLC18A2

2.37e-0323632GO:0015377
GeneOntologyMolecularFunctionamino acid:sodium symporter activity

SLC6A20 SLC1A7

2.37e-0323632GO:0005283
GeneOntologyMolecularFunctionendopeptidase inhibitor activity

SLCO1B7 USP14 WFIKKN2 SERPINA10

2.51e-03180634GO:0004866
GeneOntologyMolecularFunctionamide binding

MTR ITM2C HADHA FTCD EPHA4

2.52e-03299635GO:0033218
GeneOntologyMolecularFunctionprotein kinase activity

AKT3 LATS1 MYO3B PRKCZ ATM ZAP70 EPHA4

2.75e-03600637GO:0004672
GeneOntologyMolecularFunctionpeptidase inhibitor activity

SLCO1B7 USP14 WFIKKN2 SERPINA10

2.88e-03187634GO:0030414
GeneOntologyMolecularFunctionmonoatomic anion:monoatomic cation symporter activity

SLC6A2 SLC18A2

3.03e-0326632GO:0015296
GeneOntologyMolecularFunctionATPase-coupled intramembrane lipid transporter activity

ABCB1 ABCB4

3.51e-0328632GO:0140326
GeneOntologyMolecularFunctionamino acid:monoatomic cation symporter activity

SLC6A20 SLC1A7

3.77e-0329632GO:0005416
GeneOntologyMolecularFunctionserine-type endopeptidase inhibitor activity

SLCO1B7 WFIKKN2 SERPINA10

4.46e-03105633GO:0004867
GeneOntologyMolecularFunctionamino acid transmembrane transporter activity

SLC38A10 SLC6A20 SLC1A7

4.46e-03105633GO:0015171
GeneOntologyMolecularFunctionbicarbonate transmembrane transporter activity

SLC4A7 SLC4A10

4.57e-0332632GO:0015106
GeneOntologyMolecularFunctionmodified amino acid transmembrane transporter activity

SLC6A20 SLC22A15

4.86e-0333632GO:0072349
GeneOntologyMolecularFunctionxenobiotic transmembrane transporter activity

SLC18A2 ABCB1

5.15e-0334632GO:0042910
GeneOntologyMolecularFunctionorganic acid:sodium symporter activity

SLC6A20 SLC1A7

5.45e-0335632GO:0005343
GeneOntologyMolecularFunctionprotein serine kinase activity

AKT3 LATS1 MYO3B PRKCZ ATM

5.73e-03363635GO:0106310
GeneOntologyMolecularFunctionphosphotransferase activity, alcohol group as acceptor

AKT3 LATS1 MYO3B PRKCZ ATM ZAP70 EPHA4

6.81e-03709637GO:0016773
GeneOntologyMolecularFunctionneutral L-amino acid transmembrane transporter activity

SLC6A20 SLC1A7

7.42e-0341632GO:0015175
GeneOntologyMolecularFunctionoxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor

IMPDH1 HADHA MDH1

7.56e-03127633GO:0016616
GeneOntologyBiologicalProcessorganic anion transport

SLCO1B7 SLC22A9 EPRS1 SLC22A25 SLC38A10 SLC4A7 SV2A SLC22A11 SLC6A20 SLC4A10 SLC16A11 SLC1A7 SLC2A3 ABCB1 ABCB4

3.03e-115156315GO:0015711
GeneOntologyBiologicalProcesscarboxylic acid transport

SLCO1B7 SLC22A9 EPRS1 SLC38A10 SV2A SLC22A11 SLC6A20 SLC16A11 SLC1A7 ABCB1 ABCB4

4.08e-084106311GO:0046942
GeneOntologyBiologicalProcessorganic acid transport

SLCO1B7 SLC22A9 EPRS1 SLC38A10 SV2A SLC22A11 SLC6A20 SLC16A11 SLC1A7 ABCB1 ABCB4

4.29e-084126311GO:0015849
GeneOntologyBiologicalProcessmonoatomic ion transport

SLCO1B7 SLC6A2 SLC22A9 AKT3 SLC22A25 CNNM2 SLC4A7 PIRT SLC18A2 SLC22A11 SLC6A20 SLC22A15 SLC5A7 SLC4A10 CLDN4 SLC1A7 ABCB1

4.88e-0713746317GO:0006811
GeneOntologyBiologicalProcessinorganic anion transport

SLC4A7 ENPP1 SLC22A11 SLC4A10 CLDN4 SLC1A7 ABCB1

1.26e-06180637GO:0015698
GeneOntologyBiologicalProcessanterograde trans-synaptic signaling

SLC6A2 USP14 PTPRN2 SLC18A2 SV2B SV2A ENPP1 GLS SLC5A7 SLC4A10 PRKCZ SLC1A7 EPHA4

3.81e-069316313GO:0098916
GeneOntologyBiologicalProcesschemical synaptic transmission

SLC6A2 USP14 PTPRN2 SLC18A2 SV2B SV2A ENPP1 GLS SLC5A7 SLC4A10 PRKCZ SLC1A7 EPHA4

3.81e-069316313GO:0007268
GeneOntologyBiologicalProcesstrans-synaptic signaling

SLC6A2 USP14 PTPRN2 SLC18A2 SV2B SV2A ENPP1 GLS SLC5A7 SLC4A10 PRKCZ SLC1A7 EPHA4

4.19e-069396313GO:0099537
GeneOntologyBiologicalProcesssynaptic signaling

SLC6A2 USP14 PTPRN2 SLC18A2 SV2B SV2A ENPP1 GLS SLC5A7 SLC4A10 PRKCZ SLC1A7 EPHA4

6.37e-069766313GO:0099536
GeneOntologyBiologicalProcesscarboxylic acid transmembrane transport

SLC22A9 SLC38A10 SLC6A20 SLC16A11 SLC1A7 ABCB1

1.04e-05163636GO:1905039
GeneOntologyBiologicalProcessorganic acid transmembrane transport

SLC22A9 SLC38A10 SLC6A20 SLC16A11 SLC1A7 ABCB1

1.19e-05167636GO:1903825
GeneOntologyBiologicalProcessneurotransmitter transport

SLC6A2 PTPRN2 SLC18A2 SV2B SV2A SLC5A7 SLC1A7

1.38e-05259637GO:0006836
GeneOntologyBiologicalProcessceramide translocation

ABCB1 ABCB4

2.75e-053632GO:0099040
GeneOntologyBiologicalProcessamino acid transport

SLC6A2 SLC38A10 SV2A SLC6A20 SLC22A15 SLC1A7

2.87e-05195636GO:0006865
GeneOntologyBiologicalProcessmonocarboxylic acid transport

SLCO1B7 SLC22A9 EPRS1 SLC22A11 SLC16A11 ABCB4

4.70e-05213636GO:0015718
GeneOntologyBiologicalProcesslipid localization

SLCO1B7 SLC22A9 EPRS1 ENPP1 SLC22A11 APOF PTCH1 ABCB1 ABCB4

5.16e-05565639GO:0010876
GeneOntologyBiologicalProcesssphingolipid translocation

ABCB1 ABCB4

9.13e-055632GO:0099039
GeneOntologyBiologicalProcessmonoatomic anion transmembrane transport

SLC4A7 SLC4A10 CLDN4 SLC1A7 ABCB1

1.05e-04153635GO:0098656
GeneOntologyBiologicalProcessregeneration

CD9 ENPP1 MTR SERPINA10 PTCH1 EPHA4

1.19e-04252636GO:0031099
GeneOntologyBiologicalProcessepidermal cell fate specification

PTCH2 PTCH1

1.37e-046632GO:0009957
GeneOntologyBiologicalProcesslipid transport

SLCO1B7 SLC22A9 EPRS1 SLC22A11 APOF PTCH1 ABCB1 ABCB4

1.47e-04506638GO:0006869
GeneOntologyBiologicalProcesssodium ion transport

SLC6A2 AKT3 SLC4A7 SLC6A20 SLC5A7 SLC4A10

1.91e-04275636GO:0006814
GeneOntologyBiologicalProcessmonoatomic anion transport

SLC4A7 SLC4A10 CLDN4 SLC1A7 ABCB1

2.41e-04183635GO:0006820
GeneOntologyBiologicalProcessparanodal junction assembly

CD9 GNPAT

2.54e-048632GO:0030913
GeneOntologyBiologicalProcessnegative regulation of smoothened signaling pathway

ENPP1 PTCH2 PTCH1

2.86e-0442633GO:0045879
GeneOntologyBiologicalProcesschemical homeostasis

CNNM2 SLC4A7 PTPRN2 SV2B SV2A ENPP1 GLS SLC4A10 PTCH1 NR1D1 TMEM64 ABCB4

3.46e-0412496312GO:0048878
GeneOntologyBiologicalProcessneurotransmitter uptake

SLC6A2 SLC18A2 SLC1A7

5.39e-0452633GO:0001504
GeneOntologyBiologicalProcesschloride transport

SLC4A10 CLDN4 SLC1A7 ABCB1

6.35e-04128634GO:0006821
GeneOntologyBiologicalProcessprotein autophosphorylation

ENPP1 MYO3B ATM ZAP70 EPHA4

6.59e-04228635GO:0046777
GeneOntologyCellularComponentbasal plasma membrane

SLCO1B7 SLC22A9 SLC22A25 CNNM2 SLC4A7 ENPP1 SLC22A11 SLC4A10 CLDN4

1.09e-06354639GO:0009925
GeneOntologyCellularComponentexocytic vesicle membrane

PTPRN2 SLC18A2 SV2B SV2A SLC5A7 ATM SLC2A3

1.11e-06179637GO:0099501
GeneOntologyCellularComponentsynaptic vesicle membrane

PTPRN2 SLC18A2 SV2B SV2A SLC5A7 ATM SLC2A3

1.11e-06179637GO:0030672
GeneOntologyCellularComponentapical part of cell

SLC4A7 CD9 SLC22A11 SLC6A20 SLC5A7 SLC4A10 CLDN4 PRKCZ PTCH1 ABCB1 ABCB4

1.39e-065926311GO:0045177
GeneOntologyCellularComponentapical plasma membrane

SLC4A7 CD9 SLC22A11 SLC6A20 SLC5A7 SLC4A10 CLDN4 PRKCZ ABCB1 ABCB4

1.82e-064876310GO:0016324
GeneOntologyCellularComponentbasal part of cell

SLCO1B7 SLC22A9 SLC22A25 CNNM2 SLC4A7 ENPP1 SLC22A11 SLC4A10 CLDN4

1.88e-06378639GO:0045178
GeneOntologyCellularComponentpresynapse

SLC6A2 USP14 PTPRN2 SLC18A2 SV2B SV2A SLC5A7 SLC4A10 ATM SLC1A7 SLC2A3 EPHA4

1.13e-058866312GO:0098793
GeneOntologyCellularComponenttransport vesicle membrane

PTPRN2 SLC18A2 SV2B SV2A SLC5A7 ATM SLC2A3

2.80e-05293637GO:0030658
GeneOntologyCellularComponentsynaptic vesicle

PTPRN2 SLC18A2 SV2B SV2A SLC5A7 ATM SLC2A3

3.25e-05300637GO:0008021
GeneOntologyCellularComponentbasolateral plasma membrane

SLCO1B7 SLC22A9 SLC22A25 CNNM2 SLC4A7 ENPP1 SLC4A10

4.90e-05320637GO:0016323
GeneOntologyCellularComponentexocytic vesicle

PTPRN2 SLC18A2 SV2B SV2A SLC5A7 ATM SLC2A3

4.90e-05320637GO:0070382
GeneOntologyCellularComponentneuronal cell body

SLC6A2 SLC18A2 SV2A ENPP1 SLC5A7 SLC4A10 PRKCZ NR1D1 SLC2A3 EPHA4

1.84e-048356310GO:0043025
GeneOntologyCellularComponentintercellular canaliculus

ABCB1 ABCB4

3.17e-049632GO:0046581
GeneOntologyCellularComponentbasal dendrite

ENPP1 SLC4A10

3.96e-0410632GO:0097441
GeneOntologyCellularComponentaxon terminus

PTPRN2 SLC18A2 SLC4A10 SLC1A7 EPHA4

4.27e-04210635GO:0043679
GeneOntologyCellularComponentcell body

SLC6A2 SLC18A2 SV2A ENPP1 SLC5A7 SLC4A10 PRKCZ NR1D1 SLC2A3 EPHA4

4.30e-049296310GO:0044297
GeneOntologyCellularComponentneuron projection terminus

PTPRN2 SLC18A2 SLC4A10 SLC1A7 EPHA4

6.85e-04233635GO:0044306
GeneOntologyCellularComponentmembrane raft

MS4A4A SLC5A7 PTCH1 ZAP70 SLC2A3 ABCB4

7.66e-04362636GO:0045121
GeneOntologyCellularComponentmembrane microdomain

MS4A4A SLC5A7 PTCH1 ZAP70 SLC2A3 ABCB4

7.88e-04364636GO:0098857
GeneOntologyCellularComponenttransport vesicle

PTPRN2 SLC18A2 SV2B SV2A SLC5A7 ATM SLC2A3

9.29e-04519637GO:0030133
GeneOntologyCellularComponentsomatodendritic compartment

SLC6A2 SLC18A2 SV2A ENPP1 SLC5A7 SLC4A10 PRKCZ PTCH1 NR1D1 SLC2A3 EPHA4

1.01e-0312286311GO:0036477
GeneOntologyCellularComponentplasma membrane raft

MS4A4A SLC5A7 PTCH1 SLC2A3

1.01e-03147634GO:0044853
GeneOntologyCellularComponentaxon

SLC6A2 PTPRN2 SLC18A2 SLC5A7 SLC4A10 PRKCZ PTCH1 SLC1A7 EPHA4

1.34e-03891639GO:0030424
GeneOntologyCellularComponentcell-cell junction

SV2A CLDN4 PRKCZ ZAP70 EPHA4 ABCB1 ABCB4

1.96e-03591637GO:0005911
GeneOntologyCellularComponentdistal axon

PTPRN2 SLC18A2 SLC4A10 PTCH1 SLC1A7 EPHA4

1.96e-03435636GO:0150034
GeneOntologyCellularComponentficolin-1-rich granule

IMPDH1 PTPRN2 PSMD14 SLC2A3

2.35e-03185634GO:0101002
GeneOntologyCellularComponentanchoring junction

CD9 SV2A CLDN4 PRKCZ ZAP70 TSPAN9 EPHA4 ABCB1 ABCB4

2.49e-03976639GO:0070161
GeneOntologyCellularComponentglutamatergic synapse

USP14 CNNM2 SV2B SV2A PRKCZ SLC1A7 SLC2A3 EPHA4

3.04e-03817638GO:0098978
GeneOntologyCellularComponentterminal bouton

PTPRN2 SLC18A2 SLC1A7

3.05e-0396633GO:0043195
GeneOntologyCellularComponentsecretory vesicle

IMPDH1 CD9 PTPRN2 SLC18A2 SV2B SV2A SLC5A7 ATM PSMD14 SLC2A3

3.88e-0312466310GO:0099503
GeneOntologyCellularComponentdendrite

SLC18A2 SV2A ENPP1 SLC5A7 SLC4A10 PTCH1 NR1D1 EPHA4

4.10e-03858638GO:0030425
GeneOntologyCellularComponentdendritic tree

SLC18A2 SV2A ENPP1 SLC5A7 SLC4A10 PTCH1 NR1D1 EPHA4

4.15e-03860638GO:0097447
GeneOntologyCellularComponentapical dendrite

ENPP1 SLC4A10

4.18e-0332632GO:0097440
GeneOntologyCellularComponentperikaryon

SLC5A7 SLC4A10 SLC2A3 EPHA4

4.59e-03223634GO:0043204
GeneOntologyCellularComponentneuromuscular junction

SV2A SLC5A7 EPHA4

4.71e-03112633GO:0031594
GeneOntologyCellularComponentcytoplasmic vesicle membrane

CD9 PTPRN2 SLC18A2 SV2B SV2A SLC5A7 ATM PTCH1 SLC2A3 EPHA4

5.43e-0313076310GO:0030659
GeneOntologyCellularComponentclathrin-coated vesicle

CD9 SLC18A2 SLC5A7 ABCB4

5.69e-03237634GO:0030136
GeneOntologyCellularComponentvesicle membrane

CD9 PTPRN2 SLC18A2 SV2B SV2A SLC5A7 ATM PTCH1 SLC2A3 EPHA4

5.97e-0313256310GO:0012506
HumanPhenoOdontogenic keratocysts of the jaw

PTCH2 PTCH1

8.71e-053282HP:0010603
HumanPhenoCardiac fibroma

PTCH2 PTCH1

8.71e-053282HP:0010617
HumanPhenoOvarian fibroma

PTCH2 PTCH1

8.71e-053282HP:0010618
HumanPhenoBridged sella turcica

PTCH2 PTCH1

8.71e-053282HP:0005449
HumanPhenoBifid ribs

PTCH2 PRKCZ PTCH1

9.61e-0517283HP:0000892
DomainMFS

SLCO1B7 SLC22A9 SLC22A25 SLC18A2 SV2B SV2A SLC22A11 SLC22A15 SLC16A11 SLC2A3

2.70e-121086310PS50850
DomainMFS_dom

SLCO1B7 SLC22A9 SLC22A25 SLC18A2 SV2B SV2A SLC22A11 SLC22A15 SLC16A11 SLC2A3

2.38e-111346310IPR020846
DomainMFS_1

SLC22A9 SLC22A25 SLC18A2 SV2B SV2A SLC22A11 SLC16A11

7.04e-0977637PF07690
DomainMFS

SLC22A9 SLC22A25 SLC18A2 SV2B SV2A SLC22A11 SLC16A11

7.04e-0977637IPR011701
DomainMFS_sugar_transport-like

SV2B SV2A SLC22A11 SLC22A15 SLC2A3

1.29e-0736635IPR005828
DomainSugar_tr

SV2B SV2A SLC22A11 SLC22A15 SLC2A3

1.29e-0736635PF00083
DomainTM_rcpt_patched

PTCH2 PTCH1

1.12e-052632IPR004766
DomainSV2

SV2B SV2A

3.35e-053632IPR022308
DomainPentapeptide_4

SV2B SV2A

3.35e-053632PF13599
Domain5peptide_repeat

SV2B SV2A

6.69e-054632IPR001646
DomainAnion_exchange

SLC4A7 SLC4A10

1.11e-045632IPR001717
DomainSugar_transporter_CS

SV2B SV2A SLC2A3

1.69e-0432633IPR005829
DomainANION_EXCHANGER_2

SLC4A7 SLC4A10

2.33e-047632PS00220
DomainANION_EXCHANGER_1

SLC4A7 SLC4A10

2.33e-047632PS00219
DomainPkinase_C

AKT3 LATS1 PRKCZ

2.62e-0437633IPR017892
DomainPkinase_C

AKT3 LATS1 PRKCZ

3.82e-0442633PF00433
DomainBand3_cytoplasmic_dom

SLC4A7 SLC4A10

3.97e-049632IPR013769
DomainBand_3_cyto

SLC4A7 SLC4A10

3.97e-049632PF07565
Domain-

SLC4A7 SLC4A10

3.97e-0496323.40.1100.10
DomainPtc/Disp

PTCH2 PTCH1

3.97e-049632IPR003392
DomainPatched

PTCH2 PTCH1

3.97e-049632PF02460
DomainHCO3_cotransp

SLC4A7 SLC4A10

4.95e-0410632PF00955
DomainHCO3_transpt_C

SLC4A7 SLC4A10

4.95e-0410632IPR011531
DomainPTrfase/Anion_transptr

SLC4A7 SLC4A10

4.95e-0410632IPR016152
DomainHCO3_transpt_euk

SLC4A7 SLC4A10

4.95e-0410632IPR003020
DomainSSD

PTCH2 PTCH1

8.53e-0413632IPR000731
DomainSSD

PTCH2 PTCH1

8.53e-0413632PS50156
DomainAGC-kinase_C

AKT3 LATS1 PRKCZ

8.93e-0456633IPR000961
DomainAGC_KINASE_CTER

AKT3 LATS1 PRKCZ

8.93e-0456633PS51285
DomainS_TK_X

AKT3 LATS1 PRKCZ

8.93e-0456633SM00133
DomainNA_NEUROTRAN_SYMP_2

SLC6A2 SLC6A20

1.65e-0318632PS00754
DomainSNF

SLC6A2 SLC6A20

1.85e-0319632PF00209
DomainNA_NEUROTRAN_SYMP_1

SLC6A2 SLC6A20

1.85e-0319632PS00610
DomainNA_NEUROTRAN_SYMP_3

SLC6A2 SLC6A20

1.85e-0319632PS50267
DomainNa/ntran_symport

SLC6A2 SLC6A20

1.85e-0319632IPR000175
DomainCBS_dom

CNNM2 IMPDH1

2.05e-0320632IPR000644
DomainCBS

CNNM2 IMPDH1

2.05e-0320632PF00571
DomainCBS

CNNM2 IMPDH1

2.05e-0320632PS51371
DomainTetraspanin_CS

CD9 TSPAN9

2.26e-0321632IPR018503
DomainKinase-like_dom

AKT3 LATS1 MYO3B PRKCZ ATM ZAP70 EPHA4

2.26e-03542637IPR011009
DomainABC_membrane

ABCB1 ABCB4

2.95e-0324632PF00664
PathwayREACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

SLCO1B7 SLC6A2 SLC4A7 SLC18A2 SLC6A20 SLC22A15 SLC5A7 SLC4A10 SLC1A7 SLC2A3

8.85e-092385010MM15076
PathwayREACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

SLC6A2 SLC4A7 SLC18A2 SLC22A11 SLC6A20 SLC22A15 SLC5A7 SLC4A10 SLC1A7 SLC2A3

1.36e-082495010M5988
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

SLC6A2 SLC4A7 SLC18A2 SLC22A11 SLC6A20 SLC22A15 APOF SLC5A7 SLC4A10 PSMD14 SLC1A7 SLC2A3 ABCB1 ABCB4

1.60e-077365014M27287
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

SLCO1B7 SLC6A2 SLC4A7 SLC18A2 SLC6A20 SLC22A15 SLC5A7 SLC4A10 PSMD14 SLC1A7 SLC2A3 ABCB1 ABCB4

4.71e-076815013MM14985
PathwayREACTOME_TRANSPORT_OF_BILE_SALTS_AND_ORGANIC_ACIDS_METAL_IONS_AND_AMINE_COMPOUNDS

SLC6A2 SLC18A2 SLC22A11 SLC6A20 SLC22A15 SLC5A7

4.81e-0784506M27334
PathwayREACTOME_TRANSPORT_OF_BILE_SALTS_AND_ORGANIC_ACIDS_METAL_IONS_AND_AMINE_COMPOUNDS

SLC6A2 SLC18A2 SLC6A20 SLC22A15 SLC5A7

6.99e-0676505MM15072
PathwayREACTOME_NEUROTRANSMITTER_RELEASE_CYCLE

SLC18A2 GLS SLC5A7 SLC1A7

3.09e-0551504M4281
PathwayREACTOME_NEUROTRANSMITTER_RELEASE_CYCLE

SLC18A2 GLS SLC5A7 SLC1A7

3.09e-0551504MM14499
PathwayREACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS

SLC6A2 SLC18A2 SLC6A20

3.91e-0519503M27362
PathwayREACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS

SLC6A2 SLC18A2 SLC6A20

3.91e-0519503MM15107
PathwayREACTOME_TOXICITY_OF_BOTULINUM_TOXIN_TYPE_D_BOTD

SV2B SV2A

1.22e-045502M27427
PathwayREACTOME_UPTAKE_AND_ACTIONS_OF_BACTERIAL_TOXINS

CD9 SV2B SV2A

1.44e-0429503M27431
PathwayBIOCARTA_MRP_PATHWAY

ABCB1 ABCB4

1.83e-046502M22078
PathwayREACTOME_GLI_PROTEINS_BIND_PROMOTERS_OF_HH_RESPONSIVE_GENES_TO_PROMOTE_TRANSCRIPTION

PTCH2 PTCH1

2.56e-047502M27501
PathwayREACTOME_RHOH_GTPASE_CYCLE

SLC4A7 MTR ZAP70

2.76e-0436503MM15603
PathwayWP_AMINO_ACID_METABOLISM

EPRS1 GLS FTCD MDH1

2.98e-0491504M39570
PathwayREACTOME_RHOH_GTPASE_CYCLE

SLC4A7 MTR ZAP70

3.00e-0437503M41813
PathwayREACTOME_DISORDERS_OF_TRANSMEMBRANE_TRANSPORTERS

SLC6A2 SLC6A20 SLC5A7 PSMD14 ABCB4

3.96e-04177505M27476
PathwayWP_AMINO_ACID_METABOLISM

EPRS1 GLS FTCD MDH1

3.96e-0498504MM15942
PathwayKEGG_MEDICUS_REFERENCE_HEDGEHOG_SIGNALING_PATHWAY_PTCH_CORECEPTOR

PTCH2 PTCH1

4.37e-049502M47893
PathwayREACTOME_BICARBONATE_TRANSPORTERS

SLC4A7 SLC4A10

5.45e-0410502M27335
PathwayREACTOME_BICARBONATE_TRANSPORTERS

SLC4A7 SLC4A10

5.45e-0410502MM15073
PathwayREACTOME_NEUROTOXICITY_OF_CLOSTRIDIUM_TOXINS

SV2B SV2A

5.45e-0410502M27018
PathwayREACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES

SLC4A7 SLC6A20 SLC4A10 SLC1A7

5.72e-04108504M823
PathwayREACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES

SLC4A7 SLC6A20 SLC4A10 SLC1A7

5.92e-04109504MM15074
PathwayWP_NUCLEAR_RECEPTORS_METAPATHWAY

SLC6A2 SLC6A20 SLC5A7 SLC2A3 ABCB1 ABCB4

8.11e-04314506M39428
PathwayWP_PROXIMAL_TUBULE_TRANSPORT

SLC22A11 SLC6A20 ABCB1

1.07e-0357503M39812
PathwayKEGG_MEDICUS_REFERENCE_HEDGEHOG_SIGNALING_PATHWAY

PTCH2 PTCH1

1.09e-0314502M47414
PathwayREACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT

SLC22A11 SLC22A15

1.26e-0315502M888
PathwayREACTOME_ATORVASTATIN_ADME

SLCO1B7 ABCB1

1.26e-0315502MM15697
Pubmed

Use of a peptide mimotope to guide the humanization of MRK-16, an anti-P-glycoprotein monoclonal antibody.

ABCB1 ABCB4

3.23e-06263210488067
Pubmed

SV2 renders primed synaptic vesicles competent for Ca2+ -induced exocytosis.

SV2B SV2A

3.23e-06263219176798
Pubmed

Multidrug resistance gene expression and ABCB1 SNPs in plasma cell myeloma.

ABCB1 ABCB4

3.23e-06263221705081
Pubmed

Atypical protein kinase C zeta exhibits a proapoptotic function in ovarian cancer.

PLAAT3 PRKCZ

3.23e-06263220501645
Pubmed

The role of different P-glycoproteins in hepatobiliary secretion of fluorescently labeled short-chain phospholipids.

ABCB1 ABCB4

3.23e-06263210552998
Pubmed

Differential Coupling of Binding, ATP Hydrolysis, and Transport of Fluorescent Probes with P-Glycoprotein in Lipid Nanodiscs.

ABCB1 ABCB4

3.23e-06263228441502
Pubmed

Genetic dissection of the function of mammalian P-glycoproteins.

ABCB1 ABCB4

3.23e-0626329196326
Pubmed

Effects of cellular, chemical, and pharmacological chaperones on the rescue of a trafficking-defective mutant of the ATP-binding cassette transporter proteins ABCB1/ABCB4.

ABCB1 ABCB4

3.23e-06263222184139
Pubmed

Synaptic vesicle protein 2 binds adenine nucleotides.

SV2B SV2A

3.23e-06263218524768
Pubmed

Isolation and expression of a complementary DNA that confers multidrug resistance.

ABCB1 ABCB4

3.23e-0626323022150
Pubmed

Mammalian multidrug-resistance gene: correlation of exon organization with structural domains and duplication of an ancestral gene.

ABCB1 ABCB4

3.23e-0626322570420
Pubmed

MDR1 P-glycoprotein is a lipid translocase of broad specificity, while MDR3 P-glycoprotein specifically translocates phosphatidylcholine.

ABCB1 ABCB4

3.23e-0626328898203
Pubmed

The protein-specific activities of the transmembrane modules of Ptch1 and Ptch2 are determined by their adjacent protein domains.

PTCH2 PTCH1

3.23e-06263230166346
Pubmed

Differential overexpression of three mdr gene family members in multidrug-resistant J774.2 mouse cells. Evidence that distinct P-glycoprotein precursors are encoded by unique mdr genes.

ABCB1 ABCB4

3.23e-0626322473069
Pubmed

Common genetic variation and risk of gallbladder cancer in India: a case-control genome-wide association study.

ABCB1 ABCB4

3.23e-06263228274756
Pubmed

A missense mutation in ABCB4 gene involved in progressive familial intrahepatic cholestasis type 3 leads to a folding defect that can be rescued by low temperature.

ABCB1 ABCB4

3.23e-06263219185004
Pubmed

[Effect of papillary thyroid carcinoma related gene PTC1 on subcellular localization and function of ATM cell].

ATM PTCH1

3.23e-06263215142440
Pubmed

Polymorphisms in the drug transporter gene ABCB1 predict antidepressant treatment response in depression.

ABCB1 ABCB4

3.23e-06263218215618
Pubmed

Glycosylated SV2A and SV2B mediate the entry of botulinum neurotoxin E into neurons.

SV2B SV2A

3.23e-06263218815274
Pubmed

Brain contains two forms of synaptic vesicle protein 2.

SV2B SV2A

3.23e-0626327681585
Pubmed

What have we learnt thus far from mice with disrupted P-glycoprotein genes?

ABCB1 ABCB4

3.23e-0626328763339
Pubmed

Congenital embryonal rhabdomyosarcoma caused by heterozygous concomitant PTCH1 and PTCH2 germline mutations.

PTCH2 PTCH1

3.23e-06263229230040
Pubmed

Biliary secretion of alpha-tocopherol and the role of the mdr2 P-glycoprotein in rats and mice.

ABCB1 ABCB4

3.23e-0626329473291
Pubmed

The three mouse multidrug resistance (mdr) genes are expressed in a tissue-specific manner in normal mouse tissues.

ABCB1 ABCB4

3.23e-0626322471060
Pubmed

MDR1 and MDR3 genes and drug resistance to cisplatin of ovarian cancer cells.

ABCB1 ABCB4

3.23e-06263218231753
Pubmed

SV2 mediates entry of tetanus neurotoxin into central neurons.

SV2B SV2A

3.23e-06263221124874
Pubmed

Ptch2 loss drives myeloproliferation and myeloproliferative neoplasm progression.

PTCH2 PTCH1

3.23e-06263226834157
Pubmed

ABCB1/4 gallbladder cancer risk variants identified in India also show strong effects in Chileans.

ABCB1 ABCB4

3.23e-06263232058310
Pubmed

Mammalian multidrug resistance gene: complete cDNA sequence indicates strong homology to bacterial transport proteins.

ABCB1 ABCB4

3.23e-0626323768958
Pubmed

Role of ABCB1 and ABCB4 in renal and biliary excretion of perfluorooctanoic acid in mice.

ABCB1 ABCB4

3.23e-06263238522903
Pubmed

Localization of the human multiple drug resistance gene, MDR1, to 7q21.1.

ABCB1 ABCB4

3.23e-0626323477522
Pubmed

Inherited rare and common variants in PTCH1 and PTCH2 contributing to the predisposition to reproductive cancers.

PTCH2 PTCH1

3.23e-06263234990798
Pubmed

SV2 regulates neurotransmitter release via multiple mechanisms.

SV2B SV2A

3.23e-06263220702688
Pubmed

Clinical factors and ABCB1 polymorphisms in prediction of antiepileptic drug response: a prospective cohort study.

ABCB1 ABCB4

3.23e-06263216857572
Pubmed

Synaptic vesicle protein 2 enhances release probability at quiescent synapses.

SV2B SV2A

3.23e-06263216436618
Pubmed

Chronic continuous hypoxia decreases the expression of SLC4A7 (NBCn1) and SLC4A10 (NCBE) in mouse brain.

SLC4A7 SLC4A10

3.23e-06263217928512
Pubmed

Physical mapping, amplification, and overexpression of the mouse mdr gene family in multidrug-resistant cells.

ABCB1 ABCB4

3.23e-0626321969609
Pubmed

Expression of MDR1 and MDR3 gene products in paclitaxel-, doxorubicin- and vincristine-resistant cell lines.

ABCB1 ABCB4

3.23e-06263224140176
Pubmed

Mutations in the MDR3 gene cause progressive familial intrahepatic cholestasis.

ABCB1 ABCB4

3.23e-0626329419367
Pubmed

[Studies on keratocystic odontogenic tumors].

PTCH2 PTCH1

3.23e-06263219221557
Pubmed

Cell-specific activity of cis-acting regulatory elements in the promoter of the mouse multidrug resistance gene mdr1.

ABCB1 ABCB4

3.23e-0626322248681
Pubmed

Altered balance between excitatory and inhibitory inputs onto CA1 pyramidal neurons from SV2A-deficient but not SV2B-deficient mice.

SV2B SV2A

3.23e-06263222847229
Pubmed

Abnormal neurotransmission in mice lacking synaptic vesicle protein 2A (SV2A).

SV2B SV2A

3.23e-06263210611374
Pubmed

The role of multiple drug resistance proteins in fetal and/or placental protection against teratogen-induced orofacial clefting.

ABCB1 ABCB4

3.23e-06263217440929
Pubmed

Amplification of the murine mdr2 gene and a reconsideration of the structure of the murine mdr gene locus.

ABCB1 ABCB4

3.23e-0626327832992
Pubmed

Mdr P-glycoproteins are not essential for biliary excretion of the hydrophobic heme precursor protoporphyrin in a griseofulvin-induced mouse model of erythropoietic protoporphyria.

ABCB1 ABCB4

3.23e-06263211826402
Pubmed

SV2A and SV2B function as redundant Ca2+ regulators in neurotransmitter release.

SV2B SV2A

3.23e-06263210624962
Pubmed

mdr1a-encoded P-glycoprotein is not required for peripheral T cell proliferation, cytokine release, or cytotoxic effector function in mice.

ABCB1 ABCB4

3.23e-06263210453001
Pubmed

Molecular cloning and characterization of multispecific organic anion transporter 4 expressed in the placenta.

SLC22A9 SLC22A11

3.23e-06263210660625
Pubmed

The nuclear envelope protein Net39 is essential for muscle nuclear integrity and chromatin organization.

AKT3 SV2B SV2A

4.53e-061863333514739
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

PLAAT3 EPRS1 SLC38A10 TRMT6 PTPRN2 MYO3B SLC5A7 HADHA ATM

6.92e-0673663929676528
Pubmed

Identification of new ciliary signaling pathways in the brain and insights into neurological disorders.

CNNM2 SV2A SLC4A10 ITM2C MDH1 SLC2A3 EPHA4

8.70e-0640563738187761
Pubmed

Regulation of biliary lipid secretion by mdr2 P-glycoprotein in the mouse.

ABCB1 ABCB4

9.68e-0636327814632
Pubmed

Ptch2 mediates the Shh response in Ptch1-/- cells.

PTCH2 PTCH1

9.68e-06363225085974
Pubmed

Identification of a novel murine organic anion transporter like protein 1 (OATLP1) expressed in the kidney.

SLC22A9 SLC22A25

9.68e-06363217079864
Pubmed

Transbilayer movement of NBD-labeled phospholipids in red blood cell membranes: outward-directed transport by the multidrug resistance protein 1 (MRP1).

ABCB1 ABCB4

9.68e-0636329778357
Pubmed

Expression pattern of synaptic vesicle protein 2 (SV2) isoforms in patients with temporal lobe epilepsy and hippocampal sclerosis.

SV2B SV2A

9.68e-06363223617838
Pubmed

Different expression of catecholamine transporters in phaeochromocytomas from patients with von Hippel-Lindau syndrome and multiple endocrine neoplasia type 2.

SLC6A2 SLC18A2

9.68e-06363216189177
Pubmed

Renal expression of organic anion transporter Oat5 in rats and mice exhibits the female-dominant sex differences.

SLC22A9 SLC22A25

9.68e-06363220865662
Pubmed

Differences between nuclear run-off and mRNA levels for multidrug resistance gene expression in the cephalocaudal axis of the mouse intestine.

ABCB1 ABCB4

9.68e-0636328547326
Pubmed

Functional differences in steroid sulfate uptake of organic anion transporter 4 (OAT4) and organic anion transporting polypeptide 2B1 (OATP2B1) in human placenta.

SLC22A9 SLC22A11

9.68e-06363218501590
Pubmed

Expression of SV2 isoforms during rodent brain development.

SV2B SV2A

9.68e-06363223937191
Pubmed

Overlapping functions of stonin 2 and SV2 in sorting of the calcium sensor synaptotagmin 1 to synaptic vesicles.

SV2B SV2A

9.68e-06363226015569
Pubmed

Differentiation of two human neuroblastoma cell lines alters SV2 expression patterns.

SV2B SV2A

9.68e-06363233588752
Pubmed

Identification of serine 643 of protein kinase C-delta as an important autophosphorylation site for its enzymatic activity.

AKT3 PRKCZ

9.68e-0636329305920
Pubmed

Ptch2, a second mouse Patched gene is co-expressed with Sonic hedgehog.

PTCH2 PTCH1

9.68e-0636329462734
Pubmed

Synaptic Vesicle Protein 2 and Vesicular Monoamine Transporter 1 and 2 Are Expressed in Neuroblastoma.

SLC18A2 SV2A

9.68e-06363231317476
Pubmed

Immunolocalization of ABC drug transporters in human placenta from normal and gestational diabetic pregnancies.

ABCB1 ABCB4

9.68e-06363225029804
Pubmed

Characterization of mouse organic anion transporter 5 as a renal steroid sulfate transporter.

SLC22A9 SLC22A25

9.68e-06363216150593
Pubmed

Selected ABCB1, ABCB4 and ABCC2 polymorphisms do not enhance the risk of drug-induced hepatotoxicity in a Spanish cohort.

ABCB1 ABCB4

9.68e-06363224732756
Pubmed

Intracellular expression of P-170 glycoprotein in peripheral blood mononuclear cell subsets from healthy donors and HIV-infected patients.

ABCB1 ABCB4

9.68e-0636329542318
Pubmed

Identification of a novel organic anion transporter mediating carnitine transport in mouse liver and kidney.

SLC22A9 SLC22A25

9.68e-06363220332632
Pubmed

No major role of common SV2A variation for predisposition or levetiracetam response in epilepsy.

SV2B SV2A

9.68e-06363218977120
Pubmed

SV2 is the protein receptor for botulinum neurotoxin A.

SV2B SV2A

9.68e-06363216543415
Pubmed

Differential distribution and developmental expression of synaptic vesicle protein 2 isoforms in the mouse retina.

SV2B SV2A

9.68e-06363212687700
Pubmed

SV2 modulates the size of the readily releasable pool of secretory vesicles.

SV2B SV2A

9.68e-06363211483953
Pubmed

Functionally Distinctive Ptch Receptors Establish Multimodal Hedgehog Signaling in the Tooth Epithelial Stem Cell Niche.

PTCH2 PTCH1

9.68e-06363231145830
Pubmed

Structural and functional characterization of the mouse multidrug resistance gene family.

ABCB1 ABCB4

9.68e-0636321980424
Pubmed

Mechanism of inhibition of the tumor suppressor Patched by Sonic Hedgehog.

PTCH2 PTCH1

9.68e-06363227647915
Pubmed

Human organic anion transporter 4 is a renal apical organic anion/dicarboxylate exchanger in the proximal tubules.

SLC22A9 SLC22A11

1.93e-05463215037815
Pubmed

Loss of the SV2-like protein SVOP produces no apparent deficits in laboratory mice.

SV2B SV2A

1.93e-05463223894296
Pubmed

Fibroblast growth factor 10 is required for proper development of the mouse whiskers.

PTCH2 PTCH1

1.93e-05463212615071
Pubmed

A SCL4A10 gene product maps selectively to the basolateral plasma membrane of choroid plexus epithelial cells.

SLC4A7 SLC4A10

1.93e-05463214592810
Pubmed

Spatial distribution and developmental appearance of postjunctional P2X1 receptors on smooth muscle cells of the mouse vas deferens.

SV2B SV2A

1.93e-05463211668586
Pubmed

Analysis of a large cluster of SLC22 transporter genes, including novel USTs, reveals species-specific amplification of subsets of family members.

SLC22A9 SLC22A25

1.93e-05463219417012
Pubmed

Pharmacogenetics of OATP (SLC21/SLCO), OAT and OCT (SLC22) and PEPT (SLC15) transporters in the intestine, liver and kidney.

SLC22A9 SLC22A25

1.93e-05463218466105
Pubmed

Identification of PSD-95 as a regulator of dopamine-mediated synaptic and behavioral plasticity.

SLC6A2 SLC18A2

1.93e-05463214980210
Pubmed

Identification and functional assessment of the novel murine organic anion transporter Oat5 (Slc22a19) expressed in kidney.

SLC22A9 SLC22A25

1.93e-05463215068970
Pubmed

Overlapping and non-overlapping Ptch2 expression with Shh during mouse embryogenesis.

PTCH2 PTCH1

1.93e-0546329858693
Pubmed

[Exploring parent-of-origin effects for non-syndromic cleft lip with or without cleft palate on PTCH1, PTCH2, SHH, SMO genes in Chinese case-parent trios].

PTCH2 PTCH1

1.93e-05463233047712
Pubmed

Cotrafficking of SV2 and synaptotagmin at the synapse.

SV2B SV2A

1.93e-05463220410110
Pubmed

ATM regulates a RASSF1A-dependent DNA damage response.

LATS1 ATM

1.93e-05463219962312
Pubmed

Murine mdr-1, mdr-2, and mdr-3 gene expression: no coinduction with the Cyp1a-1 and Nmo-1 genes in liver by 2,3,7,8-tetrachlorodibenzo-p-dioxin.

ABCB1 ABCB4

1.93e-0546322069718
Pubmed

Relative structural and functional roles of multiple deubiquitylating proteins associated with mammalian 26S proteasome.

USP14 PSMD14

1.93e-05463218162577
Pubmed

Synaptotagmin 1-triggered lipid signaling facilitates coupling of exo- and endocytosis.

SV2B SV2A

1.93e-05463237738980
Pubmed

Isolation of a family of organic anion transporters from human liver and kidney.

SLC22A9 SLC22A11

1.93e-05463211327718
Pubmed

The synaptic vesicle cycle.

SLC18A2 SV2B SV2A

2.46e-053163315217342
Pubmed

Discrete gene sets depend on POU domain transcription factor Brn3b/Brn-3.2/POU4f2 for their expression in the mouse embryonic retina.

SLC18A2 PTCH2 PTCH1

2.71e-053263314973295
Pubmed

Patched1 and Patched2 inhibit Smoothened non-cell autonomously.

PTCH2 PTCH1

3.22e-05563227552050
Pubmed

Activation of protein kinase B beta and gamma isoforms by insulin in vivo and by 3-phosphoinositide-dependent protein kinase-1 in vitro: comparison with protein kinase B alpha.

AKT3 PRKCZ

3.22e-0556329512493
Cytoband12p13.3

CD9 NCAPD2 SLC2A3

9.74e-063063312p13.3
Cytoband2q12

SLC5A7 ZAP70

1.21e-04126322q12
Cytoband2q24.2

SLC4A10 PSMD14

4.21e-04226322q24.2
Cytoband11q12.3

PLAAT3 SLC22A25

1.26e-033863211q12.3
CytobandEnsembl 112 genes in cytogenetic band chr12p13

CD9 NCAPD2 TSPAN9 SLC2A3

1.43e-03353634chr12p13
Cytoband11q13.1

SLC22A9 SLC22A11

3.43e-036363211q13.1
GeneFamilySolute carriers

SLCO1B7 SLC6A2 SLC22A9 SLC22A25 SLC38A10 SLC4A7 SLC18A2 SLC22A11 SLC6A20 SLC22A15 SLC5A7 SLC4A10 SLC16A11 SLC1A7 SLC2A3

9.27e-163953815752
GeneFamilyATP binding cassette subfamily B

ABCB1 ABCB4

2.34e-0411382806
GeneFamilyCD molecules|Tetraspanins

CD9 TSPAN9

2.18e-0333382768
GeneFamilyOlfactory receptors, family 52

OR52N2 OR52N4

4.75e-0349382165
CoexpressionRATTENBACHER_BOUND_BY_CELF1

SLC6A2 TIMM17B AKT3 LATS1 CD9 PTPRN2 ENPP1 GTPBP1 EPHA4

9.71e-07444629M2505
CoexpressionZAK_PBMC_MRKAD5_HIV_1_GAG_POL_NEF_AGE_20_50YO_1DY_DN

EPRS1 AKT3 SLC4A7 DPH5 NCAPD2 SLC4A10 ATM PTCH1 NR1D1 ZAP70 EPHA4 ABCB1

3.74e-0610126212M40864
CoexpressionNAKAYA_PLASMACYTOID_DENDRITIC_CELL_FLUMIST_AGE_18_50YO_7DY_UP

PLAAT3 EPRS1 AKT3 SLC4A7 SLC18A2 GLS MTR ATM PSMD14 ABCB1 GNPAT ABCB4

2.35e-0512156212M41122
CoexpressionHE_LIM_SUN_FETAL_LUNG_C7_SST_POS_NEURON_CELL

PIRT SLC18A2 SV2A SLC5A7 PRKCZ SLC2A3 ABCB1

2.90e-05375627M45799
CoexpressionRUTELLA_RESPONSE_TO_HGF_VS_CSF2RB_AND_IL4_UP

MS4A4A AKT3 CD9 TMEM51 HADHA MDH1 SLC2A3

5.18e-05411627M19971
CoexpressionGSE6269_HEALTHY_VS_FLU_INF_PBMC_UP

DPH5 GLS PRKCZ ATM ABCB1

6.46e-05178625M5639
CoexpressionKORKOLA_CHORIOCARCINOMA_UP

CD9 SLC2A3

8.21e-056622M14050
CoexpressionGSE34156_UNTREATED_VS_24H_TLR1_TLR2_LIGAND_TREATED_MONOCYTE_UP

SLC38A10 ENPP1 SLC4A10 SERPINA10 TSPAN9

1.02e-04196625M8683
CoexpressionGSE10325_BCELL_VS_MYELOID_UP

DPH5 GLS ITM2C GTPBP1 ABCB4

1.04e-04197625M3081
CoexpressionGSE31082_DP_VS_CD4_SP_THYMOCYTE_DN

PLAAT3 AKT3 DPH5 ITM2C TSPAN9

1.09e-04199625M5065
CoexpressionGSE7460_CTRL_VS_TGFB_TREATED_ACT_TCONV_UP

DPH5 IMPDH1 CD9 ENPP1 TMEM51

1.09e-04199625M5694
CoexpressionGSE39556_UNTREATED_VS_3H_POLYIC_INJ_MOUSE_NK_CELL_DN

AKT3 CD9 SV2A GLS TSPAN9

1.12e-04200625M9411
CoexpressionGSE3039_NKT_CELL_VS_ALPHABETA_CD8_TCELL_DN

EPRS1 AKT3 SLC4A7 DPH5 GLS

1.12e-04200625M6430
CoexpressionGSE15735_2H_VS_12H_HDAC_INHIBITOR_TREATED_CD4_TCELL_UP

AKT3 SLC4A7 CD9 ITM2C TMEM64

1.12e-04200625M7159
CoexpressionGSE17186_MEMORY_VS_CD21HIGH_TRANSITIONAL_BCELL_DN

TIMM17B PLAAT3 PTCH1 ZAP70 SLC2A3

1.12e-04200625M7205
CoexpressionGSE17721_POLYIC_VS_CPG_4H_BMDC_DN

AKT3 CD9 SLC6A20 HADHA AZIN1

1.12e-04200625M3942
CoexpressionGSE7460_TCONV_VS_TREG_LN_DN

SLC4A7 ITM2C TMEM64 SLC2A3 ABCB1

1.12e-04200625M5674
CoexpressionKORKOLA_SEMINOMA_UP

CD9 TSPAN9 SLC2A3

1.56e-0444623M18387
CoexpressionFAN_EMBRYONIC_CTX_BIG_GROUPS_CAJAL_RETZIUS

PTPRN2 SV2B WFIKKN2 SLC22A15 ITM2C MDH1 TSPAN9

1.73e-04499627M39017
CoexpressionDESCARTES_FETAL_LIVER_HEPATOBLASTS

SLC22A9 SLC22A25 ENPP1 APOF SLC16A11 SERPINA10 FTCD

1.86e-04505627M40234
CoexpressionMATSUDA_NATURAL_KILLER_DIFFERENTIATION

MS4A4A SLC22A9 SLC22A25 DPH5 SV2A NCAPD2 ABCB1

2.23e-04520627MM1008
CoexpressionAtlasalpha beta T cells, NKT.4+.Sp, TCRb aGalCer-loaded CD1d-tetramer CD4, Spleen, avg-2

PLAAT3 WFIKKN2 NR1D1 ZAP70 TMEM64 SLC2A3 ABCB1

5.14e-05333627GSM538323_500
CoexpressionAtlasalpha beta T cells, T.8Eff.Sp.OT1.d15.VSVOva, CD8+ CD45.1+, Spleen, avg-2

ENPP1 CLDND2 MYO3B WFIKKN2 PRKCZ ZAP70 ABCB1

8.53e-05361627GSM538385_500
CoexpressionAtlasalpha beta T cells, T.8Eff.Sp.OT1.d10.LisOva, CD8+ CD45.1+, Spleen, avg-3

SLC4A7 CLDND2 WFIKKN2 PRKCZ ZAP70 SLC2A3 ABCB1

9.78e-05369627GSM605891_500
CoexpressionAtlasDevelopingLowerUrinaryTract_e15.5_ureteral tissue_emap-8234_top-relative-expression-ranked_1000

SLC6A2 PLAAT3 AKT3 SLC18A2 APOF MTR SERPINA10 FTCD SLC2A3 ABCB4

1.04e-048056210gudmap_developingLowerUrinaryTract_e15.5_ureteral tissue_1000
CoexpressionAtlasalpha beta T cells, T.8Eff.Sp.OT1.d6.VSVOva, CD8+ CD45.1+, Spleen, avg-3

SLC4A7 CLDND2 WFIKKN2 NCAPD2 PRKCZ ZAP70 ABCB1

1.06e-04374627GSM538389_500
CoexpressionAtlasalpha beta T cells, T.8Eff.Sp.OT1.d8.LisOva, CD8+ CD45.1+, Spleen, avg-3

SLC4A7 CLDND2 WFIKKN2 PRKCZ ZAP70 SLC2A3 ABCB1

1.17e-04380627GSM605901_500
CoexpressionAtlasgamma delta T cells, Tgd.vg2-24ahi.Th.TCRbko, TCRd+ Vg2- CD24+, Thymus, avg-3

ENPP1 NCAPD2 NR1D1 ZAP70 TMEM64 TSPAN9 ABCB1

1.51e-04396627GSM605799_500
CoexpressionAtlasNK cells, NK.49H+.Sp, NK1.1+ Ly49H+, Spleen, avg-3

PLAAT3 CD9 ENPP1 CLDND2 ZAP70 SLC2A3 ABCB1

1.69e-04403627GSM605814_500
ToppCellTCGA-Liver|World / Sample_Type by Project: Shred V9

SLC22A9 SLC22A25 APOF SERPINA10 FTCD ABCB4

1.74e-07174636452932f08cf53e5949672a025d78cecb874aa4b0
ToppCellwk_15-18-Hematologic_Lymphocytic-T_&_ILC-ILC3|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

ENPP1 SLC4A10 NR1D1 ZAP70 SLC2A3 ABCB1

2.65e-07187636a037631a01d2cce088e6522dceeb1eee806522a1
ToppCellHippocampus-Endothelial-ENDOTHELIAL_TIP|Hippocampus / BrainAtlas - Mouse McCarroll V32

ENPP1 WFIKKN2 SLC6A20 APOF TMEM64

4.03e-0616863526aa96b2b547d11941cb803995ea3d302ee0518c
ToppCellNS-critical-LOC-Lymphoid-NK|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

PLAAT3 AKT3 ZAP70 EPHA4 ABCB1

4.40e-06171635adda76991d9b150bb8ccf3989b7cbbf41843cf0b
ToppCellMild-Lymphoid-T-innate_T|Mild / Condition, Lineage, Cell class and cell subclass

SLC4A10 ITM2C NR1D1 ZAP70 ABCB1

5.50e-06179635abc0fbe101a464a2c85755a974a3d5c2b968fe46
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

AKT3 SLC4A7 MTR ITM2C ZAP70

5.80e-06181635986c036e656f24fe374807e2711cec9e3c83c892
ToppCellPCW_07-8.5-Neuronal-Neuronal_postreplicative-neuro_neuronal_(6)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

SLC6A2 PIRT SLC18A2 SLC5A7 ABCB1

6.28e-06184635571136c832cb8c08457744152231537aa8e8abd7
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_Invariant-Inducer-like|lymph-node_spleen / Manually curated celltypes from each tissue

ENPP1 SLC4A10 PTCH2 ITM2C ABCB1

6.28e-06184635d97471a4fe17cba6880ccf1a04cc00c741558124
ToppCellwk_20-22-Hematologic_Lymphocytic-T_&_ILC-ILC3|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

ENPP1 SLC4A10 ZAP70 SLC2A3 ABCB1

6.62e-06186635ac1d2a94674bd15885e70502abad3a2ff3c21d73
ToppCellwk_20-22-Hematologic_Lymphocytic-T_&_ILC-NKT1|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

SLC4A10 ATM ZAP70 SLC2A3 ABCB1

7.34e-06190635326002d7f9de5e425cee76d9a0277f42d79058e2
ToppCellPCW_05-06-Neuronal-Neuronal_postreplicative-neuro_neuronal_(6)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

SLC6A2 CD9 PIRT SLC5A7 ABCB1

7.53e-061916353a5081dc542ac6262acfe5f8084a86616fee8082
ToppCellPBMC-Control-Lymphocyte-T/NK-NK_cell-NK_CD56bright|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

AKT3 ENPP1 ZAP70 EPHA4 ABCB1

7.53e-06191635f1935e8f8467a2bc30588b7f2cc3b94e9c83b268
ToppCellwk_08-11-Epithelial-PNS-SST+_neuron|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

SLC6A2 PIRT SLC18A2 SLC5A7 ABCB1

7.53e-06191635df2bef74a54f4c23c99bd3b93225fd36bcd90723
ToppCellPBMC-Control-Lymphocyte-T/NK-NK_cell-NK_CD56bright-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

AKT3 ENPP1 ZAP70 EPHA4 ABCB1

7.53e-061916351161e465c50c2071764279e01cf08b1048cce0e3
ToppCellPBMC-Control-Lymphocyte-T/NK-NK_cell-NK_CD56bright-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

AKT3 ENPP1 ZAP70 EPHA4 ABCB1

7.53e-061916357a4fe96989f72159385270c712342ba3e1ca6fc3
ToppCellControl-Lymphoid_T/NK-NK_CD56bright|Control / Disease group, lineage and cell class

AKT3 ENPP1 ZAP70 EPHA4 ABCB1

7.53e-06191635e842f29bc03ed6734b2a7b975e7830a498f2743c
ToppCellPBMC-Control-Lymphocyte-T/NK-NK_cell-NK_CD56bright|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

AKT3 ENPP1 ZAP70 EPHA4 ABCB1

7.53e-06191635c023ca893ceae19b54967096f6e2588dc39fa268
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Cajal_Retzius-36|World / Primary Cells by Cluster

CD9 SV2B WFIKKN2 SLC22A15 ITM2C

8.33e-06195635bc76a0586cc78f013cb96a2444e63e3c5daa3bc7
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Cajal_Retzius|World / Primary Cells by Cluster

CD9 SV2B WFIKKN2 SLC22A15 ITM2C

8.33e-06195635424d8e2bc7f7e68f74219de06dbbb671c8b4c24c
ToppCellmild-low-quality_cells|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

AKT3 SLC4A7 ATM PTCH1 ZAP70

8.75e-06197635e4331969bd911d1ebb5453f40a7057297b5389b4
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c07-TYROBP|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PLAAT3 PTCH1 ZAP70 SLC1A7 ABCB1

8.75e-061976352abe27f6722fa0dab801bca4cd19e34c1fb4173e
ToppCellSepsis-URO-Lymphocyte-T/NK-gd_T|URO / Disease, condition lineage and cell class

PLAAT3 SLC16A11 ZAP70 SLC1A7 ABCB1

8.97e-06198635cb584f7754ef4e6d9ec7155022852f2d2676ab4f
ToppCellCOVID-19_Severe-NK|COVID-19_Severe / disease group, cell group and cell class

PLAAT3 ATM ZAP70 SLC1A7 ABCB1

8.97e-061986350cb88084eac25604ec8f9b1497fb8d2433f1971c
ToppCellcontrol-MAIT|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

SLC4A10 PTCH1 NR1D1 ZAP70 ABCB1

8.97e-0619863513955a4026c97e11d94973ac87bf018f64a2616c
ToppCellmild-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

AKT3 SLC4A7 GLS ATM ZAP70

9.19e-06199635f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Degenerative_Connecting_Tubule_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CD9 TMEM51 GLS ITM2C CLDN4

9.19e-061996355059a1d4df7d9989c922007a8dcba98b1f5687d5
ToppCellcontrol-MAIT|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

SLC4A10 PTCH1 NR1D1 ZAP70 ABCB1

9.41e-06200635aeea4bda2e38cc6db571ed2b47ce022d637619bd
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD8_c01-LEF1|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

USP14 MYO3B ATM GNPAT

2.80e-05123634511b7c20a4a85e49980936d52af7dbca19bb848e
ToppCellHippocampus-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Pvrl3|Hippocampus / BrainAtlas - Mouse McCarroll V32

SERPINA10 NR1D1 ZAP70 EPHA4

3.17e-051276349bc55cb9f4bddb274930784d12a83b9dceb35cb7
ToppCellNS-moderate-d_07-13-Epithelial-unknown_epithelial|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ENPP1 GLS PTCH2 CLDN4

3.47e-051306341491e8975520e99c527a5b5bee64875d124f7bf4
ToppCell356C-Lymphocytic-NK_cells-NK_cell_D3|356C / Donor, Lineage, Cell class and subclass (all cells)

MYO3B SLC4A10 ITM2C FTCD

5.61e-05147634551c249f921ee0e70208abe207f2044d234d1ddc
ToppCellBAL-Mild-Myeloid-cDC-cDC-cDC_3|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SLC18A2 ENPP1 ITM2C ABCB4

6.23e-0515163430225a1a7800b0ae19e16ac164f561379eedb99d
ToppCellPND28-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CD9 MYO3B PTCH1 NR1D1

7.42e-051586346811dc4f101dfa9a9cc13d949760d43aa522bf3b
ToppCellfacs-Marrow-B-cells-3m-Lymphocytic-BM_CD8_+_CD4_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC6A2 CNNM2 SLC6A20 ZAP70

7.79e-0516063455f599df6e3b7a5a505df4b094c834281311d94a
ToppCellfacs-Marrow-B-cells-3m-Lymphocytic-mature_alpha-beta_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC6A2 CNNM2 SLC6A20 ZAP70

7.79e-05160634296e53e1e0786346d38db2d4188b9a1c0430627b
ToppCellBAL-Mild-cDC_5|Mild / Compartment, Disease Groups and Clusters

DPH5 PTCH2 NR1D1 SLC2A3

7.98e-051616347a6e8ed0b5d999efce8945d8083ab01d71be9a92
ToppCelldroplet-Spleen-nan-24m-Lymphocytic-NK_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD9 CLDND2 SLC16A11 ZAP70

8.57e-051646347a51365bad2910c130bd952805f7a1bef51be481
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c09-SLC4A10|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

SLC4A10 NR1D1 ZAP70 ABCB1

8.78e-051656345e7ee76f3dcddbd1b560bacd043f9001b0c18b5f
ToppCellCF-Myeloid-Alveolar_Macrophage|Myeloid / Disease state, Lineage and Cell class

PLAAT3 MS4A4A CD9 MDH1

8.78e-0516563469ad83f2e4da62acfdf0a5a299d8444932a61160
ToppCellSevere-Lymphoid-NK-innate_T|Severe / Condition, Lineage, Cell class and cell subclass

SLC4A10 PTCH1 ZAP70 ABCB1

8.98e-05166634ee5ee75131fc0e22da0ceba3917f2104516af4b7
ToppCellBAL-Mild-Lymphocyte-T/NK-CD8+_T-MAIT-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SLC4A10 ITM2C ZAP70 ABCB1

8.98e-05166634bb93db4613c067c56614ab1ca39e73ee46484387
ToppCellBAL-Mild-Lymphocyte-T/NK-CD8+_T-MAIT|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SLC4A10 ITM2C ZAP70 ABCB1

8.98e-05166634c1f17a028bb27b8f202bcfffa7de7373b1cdd990
ToppCellSevere-Lymphoid-NK-CD8_T|Severe / Condition, Lineage, Cell class and cell subclass

ITM2C ZAP70 EPHA4 ABCB1

9.20e-051676348d41015871616ab7eced5104cd8f70d0efe504f2
ToppCellChildren_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

PTPRN2 SV2B SV2A SLC4A10

9.20e-05167634c87ebfa8c3284ad33579190e148c95bcaf670d17
ToppCelldroplet-Lung-nan-3m-Lymphocytic-Regulatory_T|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLAAT3 WFIKKN2 ZAP70 TMEM64

9.41e-051686341df3c8c7a6dceb901805eaba7f86f9943f4f1a9d
ToppCellfacs-Lung-18m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l21|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

WFIKKN2 NCAPD2 SLC5A7 ZAP70

9.41e-051686346c758eb120faf06ff72d157b495e399191c79ec9
ToppCelldroplet-Lung-nan-3m-Lymphocytic-regulatory_T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLAAT3 WFIKKN2 ZAP70 TMEM64

9.41e-051686341586451d437b70b2dffe41d782b694702dcaf50b
ToppCellPND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_prolif|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PLAAT3 NR1D1 ZAP70 TMEM64

9.63e-0516963420fbf78382fb0ba9a63ab1aa0abc615476994ac5
ToppCelldroplet-Lung-nan-21m-Lymphocytic-Natural_Killer_T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLAAT3 CLDND2 MYO3B ZAP70

9.63e-0516963418ba8fc2ba8838484d3b223428cd41568e2ccb10
ToppCellBAL-Control-Lymphocyte-T/NK-NK_cell-NK-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ENPP1 SLC6A20 ITM2C ABCB1

9.63e-05169634e9c0e0f4c421c7bdbf1a7e33002f3cf22ea307cb
ToppCellBAL-Control-Lymphocyte-T/NK-NK_cell|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ENPP1 SLC6A20 ITM2C ABCB1

9.63e-05169634d375a1df1ecc938f66bad92e54b8cda26ca9c472
ToppCelldroplet-Lung-nan-21m-Lymphocytic-mature_NK_T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLAAT3 CLDND2 MYO3B ZAP70

9.63e-0516963447a63afd80cb7ba2258ba57d3084d8b2a7bc4e8d
ToppCellBAL-Control-Lymphocyte-T/NK-NK_cell-NK|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ENPP1 SLC6A20 ITM2C ABCB1

9.63e-0516963458f805c0be507bd5fadc9ea3555032daabbc8ab8
ToppCellfacs-Lung-Endomucin-24m-Lymphocytic-T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRKCZ ATM NR1D1 ZAP70

9.85e-051706342b5b1f8d13b9806b76b44a53f47a23dd9ff09808
ToppCellfacs-Lung-Endomucin-24m-Lymphocytic-Ly6g5b+_T|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRKCZ ATM NR1D1 ZAP70

9.85e-0517063443c48267d8291c88263148a36fbb63c27f0e4f1c
ToppCelldroplet-Lung-30m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l9|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PLAAT3 WFIKKN2 PRKCZ ZAP70

9.85e-051706348e9b5f7bfb61f8d84d0b17fb0c191da4dabad63d
ToppCellfacs-Marrow-B-cells-18m-Lymphocytic-BM_CD4_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRN2 ENPP1 PTCH1 ZAP70

1.01e-041716346f49537f8d3cf18e65aa999fec32ed347ce2da3e
ToppCellfacs-Marrow-B-cells-18m-Lymphocytic-CD4-positive,_alpha-beta_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRN2 ENPP1 PTCH1 ZAP70

1.01e-04171634ab97ae2b127a585f170f028f1c475cdd1b0cdea5
ToppCellE12.5-Epithelial-alveolar_epithelial_cell-type_II_pneumocyte|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

PLAAT3 APOF CLDN4 SERPINA10

1.01e-04171634a4d6b0f57eead11b01153688b06b2a45a3b488f2
ToppCellControl-MAIT|Control / Disease group and Cell class

SLC4A10 NR1D1 PSMD14 TMEM64

1.03e-04172634552bc62e8e8bb0ac1cd0452f4410a3af087787eb
ToppCelldroplet-Lung-nan-21m-Myeloid-Basophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD9 SLC18A2 TMEM64 SLC2A3

1.03e-041726341b133be191252e7053faeacf9547730c3ae28d21
ToppCellURO-Lymphocyte-T_NK-gdT|URO / Disease, Lineage and Cell Type

PLAAT3 ZAP70 SLC1A7 ABCB1

1.03e-0417263497b1eb95234639fcaa5ea3c4ba7ec2f4eb929dbf
ToppCelldroplet-Lung-nan-21m-Myeloid-basophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD9 SLC18A2 TMEM64 SLC2A3

1.03e-04172634b3c53fd7e50f36de6a8585ae21d04e17932f262c
ToppCellfacs-Spleen-nan-24m-Lymphocytic-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLAAT3 CD9 TMEM51 ITM2C

1.05e-04173634e07e126e9dac6f1160cb3191d2e8374f39155d0d
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Mesenchymal-brain_pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC4A7 TMEM51 WFIKKN2 SLC16A11

1.05e-041736342415b6ff49f334da570577d4e93484d024a3dbd5
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Mesenchymal-Pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC4A7 TMEM51 WFIKKN2 SLC16A11

1.05e-041736342acd0693a2dfe04e3c1b2125ea63efe92d13150b
ToppCelldroplet-Lung-30m-Hematologic-myeloid-Basophil/Mast_cell-basophil_l26|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CD9 SLC18A2 SLC6A20 SLC2A3

1.08e-04174634009e88a6c79689a5d88b0af50aa89aa03b33f800
ToppCellTCGA-Colorectal-Recurrent_Tumor|TCGA-Colorectal / Sample_Type by Project: Shred V9

SLC22A9 SLC22A25 APOF FTCD

1.10e-041756347f74961436f88c0e380819095e6104489914d765
ToppCellPBMC-Severe-Lymphocyte-T/NK-NK_cell-NK_CD56bright-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

ATM ZAP70 EPHA4 ABCB1

1.10e-041756340ed053aa8353c72ff37fee830672704a3ddc7d85
ToppCellfacs-BAT-Fat-18m-Lymphocytic-T_cell|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLAAT3 DPH5 PRKCZ ZAP70

1.10e-04175634bf1ef77d5fed2135ac83a4f7e445ab59d1538696
ToppCellPBMC-Severe-Lymphocyte-T/NK-NK_cell-NK_CD56bright|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

ATM ZAP70 EPHA4 ABCB1

1.10e-041756340124a3c4696b39cee8b566e94603d1d3d128bfa5
ToppCellTCGA-Colorectal-Recurrent_Tumor-Colorectal_Adenocarcinoma|TCGA-Colorectal / Sample_Type by Project: Shred V9

SLC22A9 SLC22A25 APOF FTCD

1.10e-04175634bee8f31f036dfcf9fc6ed29156554771a9ee3c60
ToppCellPBMC-Severe-Lymphocyte-T/NK-NK_cell-NK_CD56bright|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ATM ZAP70 EPHA4 ABCB1

1.10e-04175634e219b61d6bc078d44ea7d06191d3462654d857a1
ToppCellPBMC-Severe-Lymphocyte-T/NK-NK_cell-NK_CD56bright-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ATM ZAP70 EPHA4 ABCB1

1.10e-04175634bd16c80418bf71127e6f1e50edf83967c9218b42
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c02-NCAM1|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ENPP1 ZAP70 EPHA4 ABCB1

1.10e-041756340c6cf88818037bef67211c1a8fcb1e7d47711c1d
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_Invariant-Inducer-like-MAIT|lymph-node_spleen / Manually curated celltypes from each tissue

SLC4A10 PTCH2 NR1D1 ABCB1

1.13e-0417663425c197d3b39deffa4801a1d12cdb54320cbae509
ToppCellfacs-Pancreas-Endocrine-24m-Epithelial-pancreatic_A_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRN2 GLS ITM2C CLDN4

1.13e-041766343027d34fd663c8a08544d469183dc45138916749
ToppCellControl-Lymphoid-ILC_B|World / Disease state, Lineage and Cell class

AKT3 ENPP1 ITM2C ABCB1

1.13e-0417663457ad9c9f5fda6bc24695587ed14190514fd8d96a
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_NK-T_mait|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

SLC4A10 ATM FTCD ABCB1

1.13e-04176634003076f1a983409ddf31b9c19e61c1facdd72566
ToppCellfacs-SCAT-Fat-18m-Lymphocytic-NK_cell|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO3B PRKCZ ZAP70 TMEM64

1.15e-04177634be35bb178fbc149f8a12984c012d98b486325ba9
ToppCellControl-Lymphoid-ILC_B|Control / Disease state, Lineage and Cell class

AKT3 ENPP1 ITM2C ABCB1

1.15e-041776343d0f4b4054185ba77071efbe53df34fee84b9b24
ToppCellControl-Epithelial_alveolar-AT_1-Differentiating_AT1|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CD9 MYO3B CLDN4 PRKCZ

1.15e-041776349af14a056eb6d88c6f11b09f6d4c0d3448d647d5
ToppCellControl-Epithelial_alveolar-AT_1|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CD9 MYO3B CLDN4 PRKCZ

1.18e-04178634aa7d43c655df493f1330a5001efaa484e4a19f69
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5-Exc_L4-5_RORB_LINC01474|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SLC22A9 SLC22A25 SV2B EPHA4

1.18e-041786345522b179c2e7dd707de01e2df10556349d0382a6
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SLC22A9 SLC22A25 SV2B EPHA4

1.18e-04178634731e1e8eff2c4018c75dfc66632a316010a09a9a
ToppCell10x5'v1-week_17-19-Lymphocytic_NK-T_NK-ILC_precursor|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

SLC4A10 NR1D1 ZAP70 ABCB1

1.20e-04179634d18a520568cf4b031972d3dd7d4d4bd073ac1fea
ToppCell10x5'v1-week_12-13-Lymphocytic_NK-T_NK-ILC_precursor|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

ENPP1 SLC4A10 NR1D1 EPHA4

1.20e-04179634bc95c3e7edc5fc6fc913b09f087d221df64c6f48
ToppCell5'-GW_trimst-1.5-LargeIntestine-Hematopoietic-T_cells-ILCP|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC4A10 NR1D1 ZAP70 ABCB1

1.23e-04180634ca7c316027e31559103b2cab1a2c0de993e42e95
ToppCell5'-GW_trimst-1.5-LargeIntestine-Hematopoietic-T_cells|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC4A10 NR1D1 ZAP70 ABCB1

1.23e-04180634eb26ba86fba26899e54c448afc25382ddc853013
ToppCellCOVID-19-kidney-tDL|COVID-19 / Disease (COVID-19 only), tissue and cell type

ENPP1 SLC22A11 FTCD ABCB1

1.23e-04180634864c895b5eaedefae86f5829fa344f7b686fb59f
ToppCellAdult-Immune-T_lymphocyte-D122|Adult / Lineage, Cell type, age group and donor

AKT3 SLC4A7 ZAP70 ABCB1

1.23e-0418063406c371d0f0c5a7b234dd143e98800e19af95a8b5
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B-Plasma_cell-B_c06-MKI67|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

PLAAT3 SLC38A10 NCAPD2 APOF

1.25e-04181634c18e5a3f5d99043fa3cb33e2ac33fa98cd15d3db
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SLC22A9 SLC22A25 SV2B EPHA4

1.25e-041816346e8c5460021d3999daec58e3d6661a6fa998fd16
ToppCell10x5'-Liver-Lymphocytic_T_CD4-T_CD4/CD8|Liver / Manually curated celltypes from each tissue

AKT3 GLS ATM SLC2A3

1.25e-04181634f2315414e714ac86211546a935660c4be6e85f1b
ToppCell5'-GW_trimst-1-SmallIntestine-Epithelial-mature_enterocytic-Enterocyte|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PLAAT3 SLC6A20 CLDN4 ABCB1

1.25e-04181634c1203787cc3f968147fabdd3c646a04be96f6552
ToppCellCOVID-19-kidney-Stressed_PCT|COVID-19 / Disease (COVID-19 only), tissue and cell type

ENPP1 SLC22A11 FTCD ABCB1

1.25e-041816346980ea624151da32b7f537f263e40fcb87a02e81
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Transitional_Principal-Intercalated_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CD9 TMEM51 ITM2C CLDN4

1.25e-04181634c2a8ee8679a1d71fcbff792cd516d3ce114f3ca6
ToppCell5'-GW_trimst-1-SmallIntestine-Epithelial-mature_enterocytic|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PLAAT3 SLC6A20 CLDN4 ABCB1

1.25e-04181634f7258af89f4cc89446ff6754bdaa769320af95d6
ToppCellHealthy_donor-MAIT|Healthy_donor / disease group, cell group and cell class (v2)

SV2A SLC4A10 NR1D1 ABCB1

1.28e-04182634ac7c83464487ecde3df6804a99551307bd768f21
ToppCellAdult-Immune-natural_killer_cell-D231|Adult / Lineage, Cell type, age group and donor

ATM PTCH1 ZAP70 ABCB1

1.28e-04182634dbf47bf4754d8ec3bc3ab1d5be7a6c47a7afbf43
ComputationalGenes in the cancer module 11.

TIMM17B PLAAT3 PTPRN2 SV2B SV2A PRKCZ NR1D1 SLC2A3 EPHA4

1.92e-04540429MODULE_11
ComputationalGenes in the cancer module 100.

TIMM17B PLAAT3 PTPRN2 SV2B SV2A PRKCZ NR1D1 SLC2A3 EPHA4

2.03e-04544429MODULE_100
ComputationalGenes in the cancer module 66.

TIMM17B PLAAT3 PTPRN2 SV2B SV2A PRKCZ NR1D1 SLC2A3 EPHA4

2.26e-04552429MODULE_66
Drugsulfinpyrazone

SLC22A9 CD9 SLC22A11 SLC16A11 ABCB1 ABCB4

1.49e-0787636CID000005342
DrugIaci

CD9 ENPP1 ABCB1

2.01e-075633CID000656579
DrugNSC 117356

SLC22A9 CD9 SLC22A11 SLC5A7 MTR SLC16A11 ABCB1 ABCB4

3.85e-07246638CID000004112
DrugPIHCA

CD9 ABCB1 ABCB4

4.01e-076633CID000108097
Drugv 104

CD9 ABCB1 ABCB4

4.01e-076633CID000107262
Drugiodoarylazidoprazosin

CD9 ABCB1 ABCB4

1.12e-068633CID000115344
Drugprobenecid

SLC22A9 CD9 SLC22A11 SLC16A11 ABCB1 ABCB4

1.16e-06123636CID000004911
Drugglutamate

EPRS1 SLC4A7 IMPDH1 SV2A GLS MTR PRKCZ HADHA FTCD MDH1 PSMD14 SLC1A7 ABCB1

1.85e-069626313CID000000611
DrugAC1NN9F1

CD9 ABCB1 ABCB4

2.39e-0610633CID000000410
Drugmercaptoacetamide

CD9 GLS ABCB1

3.28e-0611633CID000012961
Drugbenzbromarone

CD9 SLC22A11 ABCB1 ABCB4

3.28e-0637634CID000002333
DrugS 16020-2

CD9 ABCB1 ABCB4

5.66e-0613633CID000177329
Drugniguldipine

CD9 ABCB1 ABCB4 AZIN1

7.28e-0645634CID000001236
DrugL3 23

CD9 ENPP1

7.54e-062632CID000064984
Drugnaphthyl sulfate

SLC22A9 SLC22A11

7.54e-062632ctd:C029092
DrugBurgess reagent

CD9 ABCB1

7.54e-062632CID002724994
Drug1-amino-4-chloroanthraquinone

CD9 ABCB1

7.54e-062632CID000017884
DrugProtriptyline

SLC6A2 ABCB4

7.54e-062632ctd:D011530
Drug1,9-dideoxyforskolin

ABCB1 ABCB4

7.54e-062632ctd:C047983
Drug4-methylumbelliferyl sulfate

SLC22A9 SLC22A11

7.54e-062632ctd:C019492
Drugdeoxyshikonin

CD9 ABCB1

7.54e-062632CID000098914
DrugNSC3096

PTPRN2 SLC5A7 FTCD PTCH1 ABCB1

7.69e-0698635CID000002832
Drugsodium

SLC6A2 SLC4A7 SLC18A2 GLS SLC6A20 SLC5A7 MTR CLDN4 PRKCZ MDH1 SLC1A7 SLC2A3

9.12e-069446312CID000000923
Drug8-azido-ADP

CD9 ABCB1 ABCB4

1.34e-0517633CID000121934
Drugcreatine

SLC6A2 SLC18A2 MYO3B MTR ITM2C SLC1A7

1.56e-05193636CID000000586
DrugAH23848 hemicalcium salt hydrate; Up 200; 1uM; MCF7; HT_HG-U133A

DPH5 GLS ITM2C GTPBP1 NR1D1 SLC2A3

1.65e-051956366903_UP
DrugEnilconazole [35554-44-0]; Up 200; 13.4uM; PC3; HT_HG-U133A

SLC6A2 LATS1 PTPRN2 SLC6A20 APOF SLC1A7

1.65e-051956365113_UP
Drugbetaine

SLC6A2 IMPDH1 SLC18A2 SLC6A20 MTR SLC1A7

1.91e-05200636CID000000247
DrugTechnetium Tc 99m Sestamibi

ABCB1 ABCB4

2.26e-053632ctd:D017256
DrugRibavirin

IMPDH1 ENPP1

2.26e-053632DB00811
Drugdendroamide A

CD9 ABCB1

2.26e-053632CID000177307
DrugNK-250

CD9 ABCB1

2.26e-053632CID000164220
DrugD-Val-Thz

CD9 ABCB1

2.26e-053632CID003082826
DrugNortriptyline

SLC6A2 ABCB1 ABCB4

2.59e-0521633ctd:D009661
Drugthioinosinic acid

IMPDH1 ABCB1 ABCB4

3.44e-0523633CID003034391
DrugL-Glutamic Acid

EPRS1 GLS FTCD SLC1A7

3.80e-0568634DB00142
Drugcepharanthine

CD9 PRKCZ HADHA ABCB1

4.26e-0570634CID000010206
Drug6-fluorometaraminol

SLC6A2 SLC18A2

4.51e-054632CID000159475
Drugethylphenidate

SLC6A2 SLC18A2

4.51e-054632CID003080846
Drugdimethylaminobenzoate

ABCB1 ABCB4

4.51e-054632CID012241998
DrugFluorescent Dyes

SLC6A2 ABCB1

4.51e-054632ctd:D005456
DrugEphedrine

SLC6A2 SLC18A2

4.51e-054632DB01364
Drug1-aminoanthraquinone

CD9 ABCB1

4.51e-054632CID000006710
Drug4-(4-Chlorophenyl)piperidine

SLC6A2 SLC18A2

4.51e-054632CID001203613
DrugAC1NB35J

ENPP1 ABCB4

4.51e-054632CID003743673
Drug7,3',4'-trimethoxyflavone

CD9 ABCB1

4.51e-054632CID000154227
Drugnorsalsolinol

SLC6A2 SLC18A2

4.51e-054632CID000036937
Drugsulfinosine

CD9 ABCB1

4.51e-054632CID000130209
Drugerysolin

CD9 ABCB1

4.51e-054632CID003080557
Drugtariquidar

CD9 ABCB1 ABCB4

5.63e-0527633CID000148201
Drugqueuosine

USP14 EPRS1 LATS1

5.63e-0527633CID000042119
Drug4-epidoxorubicin

SLC6A2 SLC4A7 IMPDH1 CD9 MYO3B SLC5A7 PRKCZ ATM ABCB1 ABCB4

5.66e-057886310CID000001690
Drughydroxyl radicals

USP14 IMPDH1 PTPRN2 SLC18A2 ENPP1 GLS MTR PRKCZ HADHA FTCD MDH1 ABCB1 ABCB4

6.40e-0513416313CID000000961
Drughemicholinium-3

SLC6A2 SLC18A2 SLC5A7 GNPAT

6.51e-0578634CID000003585
DrugAC1L38YU

CD9 SLC18A2 SLC5A7 ABCB1

6.84e-0579634CID000085196
DrugNSC671054

CD9 ABCB1

7.50e-055632CID005357223
Druglortalamine

SLC6A2 SLC18A2

7.50e-055632CID000051047
DrugL-gamma-Glu-L-Leu

CD9 ABCB1

7.50e-055632CID000151023
Drugsuccinonitrile

ENPP1 MTR

7.50e-055632CID000008062
DrugNomifensine

SLC18A2 ABCB4

7.50e-055632ctd:D009627
DrugAC1L2MCS

ABCB1 ABCB4

7.50e-055632CID000023441
DrugLoratadine

SLC2A3 ABCB1 ABCB4

7.77e-0530633ctd:D017336
DrugAC1LCF1F

SLC22A9 CD9 SLC22A11 ABCB1 ABCB4

8.39e-05161635CID000627275
DrugTetracycline

SLC22A9 SLC6A20 APOF HADHA GTPBP1 NR1D1 SLC2A3 ABCB1 ABCB4

8.78e-05668639ctd:D013752
Drugperfluoro-n-heptanoic acid

SLC22A11 HADHA ABCB4

1.04e-0433633ctd:C101815
DrugAC1MJ1SO

SLC16A11 ABCB1 ABCB4

1.04e-0433633CID003084042
Drugchloride

SLC6A2 SLC4A7 PTPRN2 SLC18A2 SLC6A20 SLC5A7 MTR CLDN4 MDH1 SLC1A7 ABCB1

1.08e-0410296311CID000000312
DrugBisacodyl [603-50-9]; Up 200; 11uM; MCF7; HT_HG-U133A

SLC4A7 GLS NR1D1 SLC1A7 TSPAN9

1.11e-041716353297_UP
DrugDextroamphetamine

SLC6A2 SLC18A2

1.12e-046632DB01576
DrugAC1L73U3

CD9 ABCB1

1.12e-046632CID000354191
DrugAC1L99H3

ABCB1 ABCB4

1.12e-046632CID000440540
Drugniaprazine

SLC18A2 ATM

1.12e-046632CID000071919
Druglaniquidar

CD9 ABCB1

1.12e-046632CID006450806
Drug1 sq

CD9 ABCB1

1.12e-046632CID000073742
Drugalsterpaullone

CD9 ATM ABCB1

1.24e-0435633CID005005498
Drugaristolochic acid I

SV2B SLC22A11 SERPINA10 NR1D1 ABCB1

1.34e-04178635ctd:C000228
DrugMCNU

PTPRN2 ENPP1 ABCB1

1.35e-0436633CID000071741
Drugcimetidine

SLC22A9 SLC22A11 SLC16A11 ABCB1 ABCB4

1.38e-04179635CID000002756
Drugpyridoxine

IMPDH1 GLS MTR FTCD

1.40e-0495634CID000001054
Drugpseudoisocyanin

SLC6A2 ABCB1

1.57e-047632CID000075462
DrugAC1LAQXR

CD9 ENPP1

1.57e-047632CID000473367
DrugC12-NBD-PC

ABCB1 ABCB4

1.57e-047632CID006439314
Drug3,4-Methylenedioxymethamphetamine

SLC6A2 SLC18A2

1.57e-047632DB01454
DrugMMDA

SLC6A2 SLC18A2

1.57e-047632DB01442
DrugPEG-PPG-PEG

CD9 ABCB1

1.57e-047632CID010129990
Drugsarcosinamide

SLC6A2 ABCB1

1.57e-047632CID000151411
Drugoracaine

SLC6A2 SLC18A2

1.57e-047632CID000004065
Drugisovalerylshikonin

CD9 ABCB1

1.57e-047632CID000335426
DrugCaLam

CD9 ABCB1 ABCB4

1.72e-0439633CID004126474
Drugvinblastine

SLC4A7 CD9 SLC5A7 ABCB1 ABCB4

1.78e-04189635CID000013342
Drugpyridoxal 5'-phosphate

IMPDH1 GLS MTR FTCD PSMD14 AZIN1

1.83e-04301636CID000001051
Drugtetrabenazine

SLC6A2 SLC18A2 ABCB1

1.85e-0440633CID000006018
DrugFillalbin [4540-25-4]; Up 200; 13.8uM; MCF7; HT_HG-U133A

LATS1 SLC4A7 GLS ATM TSPAN9

1.91e-041926352813_UP
Drugsulfobromophthalein

SLC22A9 SLC22A11 ABCB1 ABCB4

1.92e-04103634CID000005345
DrugRoxarsone [121-19-7]; Down 200; 15.2uM; PC3; HT_HG-U133A

AKT3 CNNM2 LATS1 SLC4A7 SLC18A2

2.01e-041946355051_DN
DrugSpiramycin [8025-81-8]; Up 200; 4.8uM; MCF7; HT_HG-U133A

AKT3 SV2B SLC6A20 SLC5A7 SLC1A7

2.01e-041946353938_UP
DrugChelidonine monohydrate (+) [476-32-4]; Up 200; 10.8uM; PC3; HT_HG-U133A

AKT3 PTPRN2 SLC18A2 PTCH1 TSPAN9

2.06e-041956355760_UP
DrugRTI-121

SLC6A2 SLC18A2

2.09e-048632CID000122190
DrugAC1L1GIZ

SLC6A2 SLC18A2

2.09e-048632CID000003703
Drug11-keto-beta-boswellic acid

ENPP1 ABCB1

2.09e-048632CID006918114
DiseaseParkinson's disease (implicated_via_orthology)

AKT3 PTPRN2 SLC18A2 PTCH2 PTCH1

1.73e-05157605DOID:14330 (implicated_via_orthology)
DiseaseBASAL CELL CARCINOMA, SUSCEPTIBILITY TO, 1

PTCH2 PTCH1

2.43e-054602605462
DiseaseBasal cell carcinoma, susceptibility to, 1

PTCH2 PTCH1

2.43e-054602cv:C2751544
DiseaseOculo-dento-digital syndrome

PTCH2 PTCH1

2.43e-054602C0812437
Diseasetoxic encephalopathy (biomarker_via_orthology)

SLC18A2 EPHA4

2.43e-054602DOID:3602 (biomarker_via_orthology)
DiseasePigmented Basal Cell Carcinoma

LATS1 PTCH2 PTCH1

2.53e-0528603C1368275
DiseaseCarcinoma, Basal Cell

LATS1 PTCH2 PTCH1

2.81e-0529603C4721806
DiseaseBasal Cell Nevus Syndrome

PTCH2 PTCH1

4.05e-055602C0004779
DiseaseSchizophrenia

SLC6A2 CNNM2 SLC18A2 SV2A MTR ATM MDH1 ABCB1 GNPAT

6.95e-05883609C0036341
DiseaseColorectal Carcinoma

SLC22A9 CD9 PTPRN2 SLC22A15 PRKCZ SLC1A7 ABCB1 ABCB4

8.48e-05702608C0009402
Diseasecholestasis (biomarker_via_orthology)

SLCO1B7 ABCB1 ABCB4

1.38e-0449603DOID:13580 (biomarker_via_orthology)
DiseaseRecurrent depression

SLC6A2 SLC5A7

1.45e-049602C0221480
Diseasegallbladder neoplasm

ABCB1 ABCB4

1.45e-049602EFO_0004606
Diseasecystic fibrosis (implicated_via_orthology)

ABCB1 ABCB4

1.45e-049602DOID:1485 (implicated_via_orthology)
DiseaseMedulloblastoma

PTCH2 ATM PTCH1

1.46e-0450603C0025149
Diseaseestrogen measurement

SLC22A9 SLC22A25

1.81e-0410602EFO_0011007
Diseaseneurodegenerative disease (implicated_via_orthology)

LATS1 PTCH2 PTCH1 SLC1A7

2.20e-04145604DOID:1289 (implicated_via_orthology)
Diseasebasal cell carcinoma (is_implicated_in)

PTCH2 PTCH1

2.65e-0412602DOID:2513 (is_implicated_in)
DiseaseDepressive disorder

SLC6A2 SLC18A2 MTR NR1D1 ABCB1

3.06e-04289605C0011581
DiseaseEpstein-Barr virus infection

SLC6A2 PTPRN2 SLC22A15

3.34e-0466603EFO_0000769
DiseaseGerm Cell Cancer

CD9 SLC2A3

4.20e-0415602C0740345
DiseaseGerm cell tumor

CD9 SLC2A3

4.20e-0415602C0205851
DiseaseNeoplasms, Embryonal and Mixed

CD9 SLC2A3

4.20e-0415602C0205852
Diseaseanemia (implicated_via_orthology)

SLC4A7 SLC4A10

4.20e-0415602DOID:2355 (implicated_via_orthology)
DiseaseEmbryonal Neoplasm

CD9 SLC2A3

4.20e-0415602C0027654
DiseaseNeoplasms, Germ Cell and Embryonal

CD9 SLC2A3

4.20e-0415602C0027658
DiseaseCancer, Embryonal

CD9 SLC2A3

4.20e-0415602C0751364
DiseaseCancer, Embryonal and Mixed

CD9 SLC2A3

4.20e-0415602C0751365
Diseasemethylcobalamin deficiency type cblE, brain serotonin transporter measurement

CD9 EPHA4

4.79e-0416602EFO_0004569, MONDO_0009354
DiseaseIntrahepatic cholestasis of pregnancy

ABCB1 ABCB4

4.79e-0416602EFO_0009048
DiseaseCarcinoma of bladder

ATM EPHA4

6.09e-0418602C0699885
Diseaseresponse to mepolizumab, Glucocorticoid use measurement

TSPAN9 EPHA4

6.09e-0418602EFO_0008459, EFO_0009942
Diseaseprostate adenocarcinoma (is_implicated_in)

AKT3 CD9

7.55e-0420602DOID:2526 (is_implicated_in)
Diseasebrain measurement, neuroimaging measurement

AKT3 LATS1 SLC4A10 PRKCZ PTCH1 EPHA4

8.71e-04550606EFO_0004346, EFO_0004464
DiseaseImmunologic Deficiency Syndromes

ATM ZAP70

1.00e-0323602C0021051
Diseaselung squamous cell carcinoma (is_implicated_in)

ATM PTCH1

1.09e-0324602DOID:3907 (is_implicated_in)
Diseaseindole-3-propionate measurement

SLC6A2 TRMT6

1.38e-0327602EFO_0010501
Diseasepancreatic cancer (is_implicated_in)

MTR CLDN4 ATM

1.56e-03112603DOID:1793 (is_implicated_in)
DiseaseMental Depression

SLC6A2 SLC18A2 MTR ABCB1

1.79e-03254604C0011570
DiseaseAlzheimer's disease (is_marker_for)

HADHA ATM SLC2A3 EPHA4

1.87e-03257604DOID:10652 (is_marker_for)

Protein segments in the cluster

PeptideGeneStartEntry
MAGEIGFTMNMLDIG

AZIN1

221

O14977
LGYDLLMTMAGMSGG

APOF

221

Q13790
GMTGHLPDFCMLMVG

GTPBP1

266

O00178
GLGVVMYEMMCGRLP

AKT3

331

Q9Y243
GGILLVVPNVMGMMC

GLS

486

O94925
GLELDGMAELMAGLM

PTPRN2

326

Q92932
HGAGLPLMMLVFGEM

ABCB1

61

P08183
GGSIHPMEMEMLSLF

DPH5

256

Q9H2P9
GMESGVLMLMALDRY

OR52N4

111

Q8NGI2
GGVVQATGLVMMLMS

SLC16A11

371

Q8NCK7
ATGLVMMLMSLGGLL

SLC16A11

376

Q8NCK7
PGGDMMSLLIRMGIF

LATS1

786

O95835
MLRGIGSGMKYLSDM

EPHA4

726

P54764
LDITPMMGVLDGVLM

MDH1

41

P40925
VDGMVGMLMDGLKEL

ENPP1

396

P22413
GMESGVLMLMALDRY

OR52N2

111

Q8NGI0
ADMAIAMALMGGIGF

IMPDH1

76

P20839
GGVCYLSMGMVVLLM

ITM2C

56

Q9NQX7
LSMGMVVLLMGLVFA

ITM2C

61

Q9NQX7
TIMAIAHGSGLPLMM

ABCB4

61

P21439
QELGAMGMGDLLSAM

NR1D1

506

P20393
RMGTKMMGGLGFHEV

ATM

2526

Q13315
IGIAVVMIFGMIFSM

CD9

201

P21926
VFFSATMGIMLGRMG

SLC1A7

226

O00341
AAGMDFLGMKMVGEL

GNPAT

186

O15228
FLGMKMVGELLRMSG

GNPAT

191

O15228
GTMSILMGLDGMVLL

MS4A4A

176

Q96JQ5
MVGVPAALDMMLTGR

HADHA

191

P40939
MIGLGGMAFCSTLMT

SLC2A3

336

P11169
IFFMVMPIMIGGFGN

MT-CO1

66

P00395
VGRLGAMMGPLILMS

SLC22A11

471

Q9NSA0
LVGMMNGGMSLVAFV

SLC22A15

171

Q8IZD6
SVAKFLFMAGMMVGG

SLC22A25

146

Q6T423
GKMLVETSMIGLMLG

SLC38A10

81

Q9HBR0
MGAALGSMVGLMTYG

FTCD

366

O95954
RAGVPMEVMGLMLGE

PSMD14

46

O00487
MGGLLFIPALMGEMF

SLC5A7

126

Q9GZV3
MLLALGLDSSMGGME

SLC6A2

411

P23975
GVMTMVHGDNMGLVL

EPRS1

1281

P07814
LMVGVMLGVCSVMGL

SLC4A7

956

Q9Y6M7
TGLMIFILMGLSVFM

SLC4A7

1011

Q9Y6M7
GMGLAAMSLIGVMFS

PLAAT3

141

P53816
GMIVYLGMMAGAFIL

SV2B

151

Q7L1I2
SVAKFVFMAGMMVGG

SLC22A9

146

Q8IVM8
MVGPGFLSLGLMMLV

PIRT

91

P0C851
MGLMVFLIYLGGMMV

MT-ND6

51

P03923
LAMMTVELFGIMGFL

PTCH2

996

Q9Y6C5
LQKRIMVLDGGMGTM

MTR

26

Q99707
ALMTVELFGMMGLIG

PTCH1

1061

Q13635
NVMGMTGLVFAFMLG

SLCO1B7

166

G3V0H7
FFMLLMLGIGSMLGN

SLC6A20

396

Q9NP91
MLGLIVYLGMMVGAF

SV2A

206

Q7L0J3
MASMGLQVMGIALAV

CLDN4

1

O14493
MVLAVGVGVVGMVMG

CLDND2

66

Q8NHS1
MLLGMMARGKPEIVG

NCAPD2

776

Q15021
MFSGLNLGLMALDPM

CNNM2

271

Q9H8M5
FVLGMGLMMVGVLIG

TMEM64

191

Q6YI46
MLVMEMAGGGPLHKF

ZAP70

411

P43403
LLMVAVMLGVCSIMG

SLC4A10

856

Q6U841
AIGLGMLVLGVIMAM

TMEM51

16

Q9NW97
AMVGSAMMGGILLAL

TIMM17B

111

O60830
SPFGMSLAMTGLMLG

SERPINA10

101

Q9UK55
AMMERMGGFGSIIQL

TRMT6

216

Q9UJA5
GMTLLMMGSADALPE

USP14

66

P54578
VGFAIGMVDSSMMPI

SLC18A2

391

Q05940
GTVGMCILIMQILGM

TSPAN9

206

O75954
PLIIMGEVDGGMAML

WFIKKN2

526

Q8TEU8
ALGVLMFEMMAGRSP

PRKCZ

436

Q05513
LEMMFTPTGVVMGAR

MYO3B

496

Q8WXR4