Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionextracellular matrix constituent, lubricant activity

MUC17 MUC3A MUC4

4.27e-084453GO:0030197
GeneOntologyMolecularFunctionaryl hydrocarbon receptor binding

NCOA2 TAF6

1.77e-049452GO:0017162
GeneOntologyMolecularFunctionmismatch repair complex binding

MLH1 PCNA

2.70e-0411452GO:0032404
GeneOntologyMolecularFunctionmismatched DNA binding

MLH1 PCNA

4.44e-0414452GO:0030983
GeneOntologyMolecularFunctionDNA polymerase binding

NCOA2 PCNA

1.22e-0323452GO:0070182
GeneOntologyMolecularFunctionstructural constituent of nuclear pore

POM121L2 NPAP1

1.44e-0325452GO:0017056
GeneOntologyMolecularFunctionnuclear localization sequence binding

POM121L2 NPAP1

1.68e-0327452GO:0008139
GeneOntologyMolecularFunctionDNA-binding transcription factor binding

NCOA2 KMT2A TBX3 TAF6 MED13 PCNA

1.85e-03582456GO:0140297
GeneOntologyBiologicalProcessureteric peristalsis

TBX3 TSHZ3

1.33e-053442GO:0072105
GeneOntologyBiologicalProcessureter smooth muscle contraction

TBX3 TSHZ3

1.33e-053442GO:0014849
GeneOntologyBiologicalProcessmammary placode formation

TBX3 NRG3

2.66e-054442GO:0060596
GeneOntologyCellularComponentGolgi lumen

MUC19 MUC16 MUC5B MUC3B MUC17 MUC3A MUC4

4.57e-09109477GO:0005796
GeneOntologyCellularComponentMLL1 complex

KMT2A TAF6 MGA

5.05e-0532473GO:0071339
GeneOntologyCellularComponentMLL1/2 complex

KMT2A TAF6 MGA

5.54e-0533473GO:0044665
GeneOntologyCellularComponentcyclin-dependent protein kinase holoenzyme complex

CCNB3 MED13 PCNA

3.50e-0461473GO:0000307
GeneOntologyCellularComponenthistone methyltransferase complex

KMT2A TAF6 MGA

6.42e-0475473GO:0035097
GeneOntologyCellularComponentnuclear protein-containing complex

NCOA2 MLH1 KMT2A POM121L2 ATF1 TAF6 MGA MED13 PCNA NPAP1

8.18e-0413774710GO:0140513
HumanPhenoThin vermilion border

SCYL2 KMT2A NBAS HUWE1 TAF6 MED13 NPAP1

1.66e-05433127HP:0000233
DomainSEA

MUC16 MUC3B MUC17 MUC3A

2.64e-0814444SM00200
DomainVWD

MUC19 MUC5B ZAN MUC4

4.78e-0816444SM00216
DomainVWF_type-D

MUC19 MUC5B ZAN MUC4

4.78e-0816444IPR001846
DomainVWFD

MUC19 MUC5B ZAN MUC4

4.78e-0816444PS51233
DomainVWD

MUC19 MUC5B ZAN MUC4

4.78e-0816444PF00094
DomainSEA

MUC16 MUC3B MUC17 MUC3A

2.30e-0723444PS50024
DomainSEA_dom

MUC16 MUC3B MUC17 MUC3A

2.30e-0723444IPR000082
DomainEGF_3

MUC3B NRG3 ZAN MUC17 MUC3A MUC4 LRP8

1.18e-06235447PS50026
DomainEGF

MUC3B NRG3 ZAN MUC17 MUC3A MUC4 LRP8

1.18e-06235447SM00181
DomainEGF-like_dom

MUC3B NRG3 ZAN MUC17 MUC3A MUC4 LRP8

1.73e-06249447IPR000742
DomainEGF_1

MUC3B NRG3 ZAN MUC17 MUC3A MUC4 LRP8

2.03e-06255447PS00022
DomainEGF-like_CS

MUC3B NRG3 ZAN MUC17 MUC3A MUC4 LRP8

2.37e-06261447IPR013032
DomainEGF_2

MUC3B NRG3 ZAN MUC17 MUC3A MUC4 LRP8

2.62e-06265447PS01186
DomainTIL

MUC19 MUC5B ZAN

2.64e-0612443PF01826
DomainC8

MUC19 MUC5B ZAN

2.64e-0612443PF08742
DomainUnchr_dom_Cys-rich

MUC19 MUC5B ZAN

3.43e-0613443IPR014853
DomainC8

MUC19 MUC5B ZAN

3.43e-0613443SM00832
DomainTIL_dom

MUC19 MUC5B ZAN

4.36e-0614443IPR002919
DomainVWC_out

MUC19 MUC5B ZAN

1.15e-0519443SM00215
DomainSEA

MUC16 MUC3B MUC17

1.82e-0522443PF01390
DomainVWC

MUC19 MUC5B ZAN

9.71e-0538443SM00214
DomainVWFC_2

MUC19 MUC5B ZAN

9.71e-0538443PS50184
DomainVWF_dom

MUC19 MUC5B ZAN

1.31e-0442443IPR001007
DomainEGF

NRG3 ZAN MUC4 LRP8

2.18e-04126444PF00008
Domain-

MUC16 MUC17

5.59e-04154423.30.70.960
DomainTF_T-box

TBX3 MGA

7.21e-0417442IPR001699
DomainTBOX

TBX3 MGA

7.21e-0417442SM00425
DomainTF_T-box_CS

TBX3 MGA

7.21e-0417442IPR018186
Domain-

TBX3 MGA

7.21e-04174422.60.40.820
DomainTBOX_3

TBX3 MGA

7.21e-0417442PS50252
DomainT-box

TBX3 MGA

7.21e-0417442PF00907
DomainTBOX_1

TBX3 MGA

7.21e-0417442PS01283
DomainTBOX_2

TBX3 MGA

7.21e-0417442PS01264
DomainCTCK_1

MUC19 MUC5B

8.10e-0418442PS01185
DomainARM-type_fold

SCYL2 HUWE1 TAF6 HECTD1 MAP3K1

1.16e-03339445IPR016024
DomainCT

MUC19 MUC5B

1.22e-0322442SM00041
DomainCys_knot_C

MUC19 MUC5B

1.57e-0325442IPR006207
DomainCTCK_2

MUC19 MUC5B

1.57e-0325442PS01225
DomainHECT

HUWE1 HECTD1

1.83e-0327442PF00632
DomainHECTc

HUWE1 HECTD1

1.83e-0327442SM00119
DomainHECT_dom

HUWE1 HECTD1

1.83e-0327442IPR000569
DomainHECT

HUWE1 HECTD1

1.83e-0327442PS50237
DomainVWFC_1

MUC5B ZAN

3.25e-0336442PS01208
DomainARM-like

SCYL2 HUWE1 TAF6 HECTD1

3.68e-03270444IPR011989
PathwayREACTOME_DEFECTIVE_GALNT3_CAUSES_HFTC

MUC16 MUC5B MUC17 MUC3A MUC4

4.63e-1016385M27410
PathwayREACTOME_DEFECTIVE_C1GALT1C1_CAUSES_TNPS

MUC16 MUC5B MUC17 MUC3A MUC4

6.54e-1017385M27412
PathwayREACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS

MUC19 MUC16 MUC5B MUC17 MUC4

2.14e-0921385MM15706
PathwayREACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS

MUC16 MUC5B MUC17 MUC3A MUC4

3.52e-0923385M556
PathwayREACTOME_DECTIN_2_FAMILY

MUC16 MUC5B MUC17 MUC3A MUC4

6.84e-0926385M27483
PathwayREACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS

MUC19 MUC16 MUC5B MUC17 MUC4

5.31e-0760385MM15636
PathwayREACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS

MUC16 MUC5B MUC17 MUC3A MUC4

6.27e-0762385M546
PathwayREACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS

MUC16 MUC5B MUC17 MUC3A MUC4

9.98e-0768385M27303
PathwayREACTOME_O_LINKED_GLYCOSYLATION

MUC19 MUC16 MUC5B MUC17 MUC4

1.03e-05109385MM15164
PathwayREACTOME_O_LINKED_GLYCOSYLATION

MUC16 MUC5B MUC17 MUC3A MUC4

1.13e-05111385M27416
PathwayREACTOME_C_TYPE_LECTIN_RECEPTORS_CLRS

MUC16 MUC5B MUC17 MUC3A MUC4

3.47e-05140385M27484
PathwayREACTOME_DISEASES_OF_GLYCOSYLATION

MUC16 MUC5B MUC17 MUC3A MUC4

3.84e-05143385M27275
PathwayWP_OXIDATIVE_DAMAGE_RESPONSE

OPRPN MAP3K1 PCNA

1.93e-0442383MM15945
PathwayWP_MISMATCH_REPAIR

MLH1 PCNA

2.52e-049382MM15932
PathwayREACTOME_DISEASES_OF_METABOLISM

MUC16 MUC5B MUC17 MUC3A MUC4

5.24e-04250385M27554
PathwayREACTOME_INNATE_IMMUNE_SYSTEM

MUC16 MUC5B ATF1 HUWE1 DSC1 MUC17 MUC3A MUC4 CD300A MAP3K1

6.14e-0411283810M1036
PathwayREACTOME_MISMATCH_REPAIR

MLH1 PCNA

7.27e-0415382M27442
PathwayREACTOME_MISMATCH_REPAIR

MLH1 PCNA

7.27e-0415382MM15184
Pubmed

Mucin gene expression in human laryngeal epithelia: effect of laryngopharyngeal reflux.

MUC19 MUC16 MUC5B MUC17 MUC3A MUC4

9.16e-141848618834073
Pubmed

Genomic organization and structure of the 3' region of human MUC3: alternative splicing predicts membrane-bound and soluble forms of the mucin.

MUC3B MUC17 MUC3A

2.47e-09348310512748
Pubmed

Expression of Muc19/Smgc gene products during murine sublingual gland development: cytodifferentiation and maturation of salivary mucous cells.

MUC19 MUC16 MUC5B

4.92e-08648319110483
Pubmed

Initiation of transcription of the MUC3A human intestinal mucin from a TATA-less promoter and comparison with the MUC3B amino terminus.

MUC3B MUC3A

1.87e-06248212958310
Pubmed

The beta sliding clamp binds to multiple sites within MutL and MutS.

MLH1 PCNA

1.87e-06248216546997
Pubmed

Multiple transcripts of MUC3: evidence for two genes, MUC3A and MUC3B.

MUC3B MUC3A

1.87e-06248210973822
Pubmed

MUC3 human intestinal mucin. Analysis of gene structure, the carboxyl terminus, and a novel upstream repetitive region.

MUC3B MUC3A

1.87e-0624829334251
Pubmed

Molecular cloning of cDNAs derived from a novel human intestinal mucin gene.

MUC3B MUC3A

1.87e-0624822393399
Pubmed

Associations of distinct variants of the intestinal mucin gene MUC3A with ulcerative colitis and Crohn's disease.

MUC3B MUC3A

1.87e-06248211289722
Pubmed

Immunocytochemistry for MUC4 and MUC16 is a useful adjunct in the diagnosis of pancreatic adenocarcinoma on fine-needle aspiration cytology.

MUC16 MUC4

1.87e-06248223544943
Pubmed

Expression of mucins in mucoid otitis media.

MUC5B MUC4

1.87e-06248214690056
Pubmed

The MUC3 gene encodes a transmembrane mucin and is alternatively spliced.

MUC3B MUC3A

1.87e-06248210405327
Pubmed

Regulation of oxidative DNA damage repair by DNA polymerase λ and MutYH by cross-talk of phosphorylation and ubiquitination.

HUWE1 PCNA

5.59e-06348222203964
Pubmed

Microbial products alter the expression of membrane-associated mucin and antimicrobial peptides in a three-dimensional human endocervical epithelial cell model.

MUC16 MUC4

5.59e-06348223053434
Pubmed

Expression of mucin (MUC) genes in mucoepidermoid carcinoma.

MUC19 MUC4

5.59e-06348221072847
Pubmed

DUSP28 links regulation of Mucin 5B and Mucin 16 to migration and survival of AsPC-1 human pancreatic cancer cells.

MUC16 MUC5B

5.59e-06348227230679
Pubmed

Integrative analysis of the cancer genome atlas and cancer cell lines encyclopedia large-scale genomic databases: MUC4/MUC16/MUC20 signature is associated with poor survival in human carcinomas.

MUC16 MUC4

5.59e-06348230236127
Pubmed

Expression of mucin 3 and mucin 5AC in arthritic synovial tissue.

MUC3B MUC3A

5.59e-06348218163520
Pubmed

Interaction of proliferating cell nuclear antigen with PMS2 is required for MutLα activation and function in mismatch repair.

MLH1 PCNA

5.59e-06348228439008
Pubmed

Regulation of membrane-associated mucins in the human corneal epithelial cells by dexamethasone.

MUC16 MUC4

5.59e-06348217592322
Pubmed

Two atypical enteropathogenic Escherichia coli strains induce the production of secreted and membrane-bound mucins to benefit their own growth at the apical surface of human mucin-secreting intestinal HT29-MTX cells.

MUC17 MUC4

5.59e-06348220065027
Pubmed

Recurrent YAP1 and KMT2A Gene Rearrangements in a Subset of MUC4-negative Sclerosing Epithelioid Fibrosarcoma.

KMT2A MUC4

5.59e-06348231592798
Pubmed

Genome-wide bidirectional CRISPR screens identify mucins as host factors modulating SARS-CoV-2 infection.

MUC16 MUC4

5.59e-06348235879412
Pubmed

Functional Consequences of Differential O-glycosylation of MUC1, MUC4, and MUC16 (Downstream Effects on Signaling).

MUC16 MUC4

5.59e-06348227483328
Pubmed

MicroRNA-200c modulates the expression of MUC4 and MUC16 by directly targeting their coding sequences in human pancreatic cancer.

MUC16 MUC4

5.59e-06348224204560
Pubmed

Expression of the transmembrane mucins, MUC1, MUC4 and MUC16, in normal endometrium and in endometriosis.

MUC16 MUC4

5.59e-06348224939955
Pubmed

Whole exome sequencing identifies MAP3K1, MSH2, and MLH1 as potential cancer-predisposing genes in familial early-onset colorectal cancer.

MLH1 MAP3K1

5.59e-06348237314251
Pubmed

Interaction network of human early embryonic transcription factors.

NCOA2 KMT2A TBX3 TSHZ3 MGA EMSY

8.69e-0635148638297188
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

SCYL2 NCOA2 KMT2A HUWE1 TAF6 MGA EMSY

9.88e-0654948738280479
Pubmed

Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF.

KMT2A TAF6 MGA

1.08e-053148315960975
Pubmed

FAN1 interaction with ubiquitylated PCNA alleviates replication stress and preserves genomic integrity independently of BRCA2.

MLH1 PCNA

1.12e-05448229051491
Pubmed

Secalonic acid D alters the expression and phosphorylation of the transcription factors and their binding to cAMP response element in developing murine secondary palate.

ATF1 PCNA

1.12e-05448211354513
Pubmed

HUWE1 interacts with PCNA to alleviate replication stress.

HUWE1 PCNA

1.12e-05448227146073
Pubmed

Nuclear reorganization of DNA mismatch repair proteins in response to DNA damage.

MLH1 PCNA

1.12e-05448220004149
Pubmed

TRPV4 activation in human corneal epithelial cells promotes membrane mucin production.

MUC16 MUC4

1.12e-05448239024979
Pubmed

Butyrate enemas upregulate Muc genes expression but decrease adherent mucus thickness in mice colon.

MUC17 MUC4

1.12e-05448218198997
Pubmed

Genetic variation in genes interacting with BRCA1/2 and risk of breast cancer in the Cypriot population.

MLH1 ATF1 PCNA

1.31e-053348319714462
Pubmed

Polymorphism of human mucin genes in chest disease: possible significance of MUC2.

MUC5B MUC4

1.86e-05548211062147
Pubmed

PCNA activates the MutLγ endonuclease to promote meiotic crossing over.

MLH1 PCNA

1.86e-05548232814343
Pubmed

Multifaceted transcriptional regulation of the murine intestinal mucus layer by endogenous microbiota.

MUC17 MUC4

1.86e-05548218035521
Pubmed

Activity-Based Probes for HECT E3 Ubiquitin Ligases.

HUWE1 HECTD1

1.86e-05548228425671
Pubmed

Characterization of human exonuclease 1 in complex with mismatch repair proteins, subcellular localization and association with PCNA.

MLH1 PCNA

1.86e-05548214676842
Pubmed

A novel mechanism of G protein-dependent phosphorylation of vasodilator-stimulated phosphoprotein.

VASP MAP3K1

1.86e-05548216046415
Pubmed

Genomic instability in mice lacking histone H2AX.

MLH1 PCNA

2.79e-05648211934988
Pubmed

Regulation of the MLH1-MLH3 endonuclease in meiosis.

MLH1 PCNA

2.79e-05648232814904
Pubmed

Identification of proximal SUMO-dependent interactors using SUMO-ID.

NCOA2 TBX3 TAF6 MGA EMSY PCNA

3.26e-0544448634795231
Pubmed

Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.

NCOA2 KMT2A MGA MED13 EMSY

3.42e-0526848533640491
Pubmed

Identification of the scaramanga gene implicates Neuregulin3 in mammary gland specification.

TBX3 NRG3

3.90e-05748216140987
Pubmed

A defined human system that supports bidirectional mismatch-provoked excision.

MLH1 PCNA

3.90e-05748215225546
Pubmed

Induced alpha-helix structure in the aryl hydrocarbon receptor transactivation domain modulates protein-protein interactions.

NCOA2 TAF6

3.90e-05748215641800
Pubmed

Targeted disruption of exons 1 to 6 of the Fanconi Anemia group A gene leads to growth retardation, strain-specific microphthalmia, meiotic defects and primordial germ cell hypoplasia.

MLH1 PCNA

3.90e-05748212913077
Pubmed

GATA-Binding Factor 6 Contributes to Atrioventricular Node Development and Function.

TBX3 PCNA

5.19e-05848225613430
Pubmed

An Oct4-centered protein interaction network in embryonic stem cells.

TAF6 MGA MED13 EMSY

8.46e-0516748420362541
Pubmed

Lineage and morphogenetic analysis of the cardiac valves.

TBX3 PCNA

1.02e-041148215297379
Pubmed

Mammalian BTBD12 (SLX4) protects against genomic instability during mammalian spermatogenesis.

MLH1 PCNA

1.22e-041248221655083
Pubmed

Generation and comprehensive analysis of an influenza virus polymerase cellular interaction network.

TAF6 PCNA

1.22e-041248221994455
Pubmed

NCOA2 promotes lytic reactivation of Kaposi's sarcoma-associated herpesvirus by enhancing the expression of the master switch protein RTA.

NCOA2 HECTD1 PCNA

1.27e-047048331751430
Pubmed

The deubiquitinase USP9X regulates FBW7 stability and suppresses colorectal cancer.

KMT2A HUWE1 HECTD1

1.32e-047148329346117
Pubmed

MKRN2 Physically Interacts with GLE1 to Regulate mRNA Export and Zebrafish Retinal Development.

TBX3 ATF1 HUWE1 VASP LRP8

1.34e-0435848532460013
Pubmed

Diminished pancreatic beta-cell mass in securin-null mice is caused by beta-cell apoptosis and senescence.

MLH1 PCNA

1.44e-041348219213844
Pubmed

DNA repair protein FANCD2 has both ubiquitination-dependent and ubiquitination-independent functions during germ cell development.

MLH1 PCNA

1.44e-041348236642183
Pubmed

Identification of KIAA1018/FAN1, a DNA repair nuclease recruited to DNA damage by monoubiquitinated FANCD2.

MLH1 PCNA

1.94e-041548220603015
Pubmed

Ectodysplasin/NF-κB Promotes Mammary Cell Fate via Wnt/β-catenin Pathway.

TBX3 NRG3

2.21e-041648226581094
Pubmed

LGALS3BP regulates centriole biogenesis and centrosome hypertrophy in cancer cells.

KMT2A HUWE1 DSC1 HECTD1 VASP PCNA

2.39e-0463948623443559
Pubmed

Teashirt 3 is necessary for ureteral smooth muscle differentiation downstream of SHH and BMP4.

TSHZ3 PCNA

2.50e-041748218776146
Pubmed

Genetic determinants of P wave duration and PR segment.

TBX3 MED13

2.50e-041748224850809
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

SCYL2 MLH1 KMT2A TAF6 DSC1 EMSY PCNA

2.78e-0493448733916271
Pubmed

Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.

MLH1 TBX3 HUWE1 MGA HECTD1 VASP MED13 PCNA

2.81e-04124748827684187
Pubmed

DVC1 (C1orf124) is a DNA damage-targeting p97 adaptor that promotes ubiquitin-dependent responses to replication blocks.

MLH1 PCNA

2.81e-041848223042605
Pubmed

Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.

TSHZ3 MGA VASP MAP3K1 STON2

3.12e-0443048535044719
Pubmed

Haploinsufficiency of SAMD9L, an endosome fusion facilitator, causes myeloid malignancies in mice mimicking human diseases with monosomy 7.

MUC19 MUC4 STON2

3.12e-049548324029230
Pubmed

An ARC/Mediator subunit required for SREBP control of cholesterol and lipid homeostasis.

KMT2A MED13

3.14e-041948216799563
Pubmed

STAGA recruits Mediator to the MYC oncoprotein to stimulate transcription and cell proliferation.

TAF6 MED13

3.49e-042048217967894
Pubmed

ALL-1 is a histone methyltransferase that assembles a supercomplex of proteins involved in transcriptional regulation.

KMT2A TAF6

3.85e-042148212453419
Pubmed

NuRD subunit CHD4 regulates super-enhancer accessibility in rhabdomyosarcoma and represents a general tumor dependency.

KMT2A TSHZ3 TAF6

3.96e-0410348332744500
Pubmed

Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

TRAK2 MGA MED13

4.19e-041054839628581
Pubmed

A mouse knockout library for secreted and transmembrane proteins.

MUC16 HAVCR1 SCPEP1 TMEM123 CD300A

4.25e-0446048520562862
Pubmed

Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.

KMT2A NBAS TAF6 MGA HECTD1 MED13 EMSY NPAP1

4.26e-04132748832694731
Pubmed

Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.

KMT2A HUWE1 USP42 MUC4 PCNA

4.64e-0446948527634302
Pubmed

E-cadherin is required for intestinal morphogenesis in the mouse.

MUC17 MUC4

5.05e-042448222766025
Pubmed

Single nucleotide polymorphisms in miRNA binding sites and miRNA genes as breast/ovarian cancer risk modifiers in Jewish high-risk women.

ATF1 PCNA

5.05e-042448219950226
Pubmed

The human CDK8 subcomplex is a molecular switch that controls Mediator coactivator function.

TAF6 MED13

5.48e-042548219240132
Pubmed

System-Wide Modulation of HECT E3 Ligases with Selective Ubiquitin Variant Probes.

HUWE1 HECTD1

5.93e-042648226949039
Pubmed

Bmp2 and Notch cooperate to pattern the embryonic endocardium.

TBX3 PCNA

5.93e-042648229853617
Pubmed

MRNIP interacts with sex body chromatin to support meiotic progression, spermatogenesis, and male fertility in mice.

MLH1 PCNA

5.93e-042648235920200
Pubmed

CEP63 deficiency promotes p53-dependent microcephaly and reveals a role for the centrosome in meiotic recombination.

MLH1 PCNA

6.40e-042748226158450
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

KMT2A HUWE1 TAF6 USP42 MED13 EMSY

6.60e-0477448615302935
Pubmed

Quantitative interaction proteomics and genome-wide profiling of epigenetic histone marks and their readers.

TAF6 MGA EMSY

6.80e-0412448320850016
Pubmed

Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.

MUC19 EMSY

6.89e-042848218587394
Pubmed

Human transcription factor protein interaction networks.

NCOA2 KMT2A TSHZ3 ATF1 TAF6 MGA EMSY PCNA

6.94e-04142948835140242
Pubmed

New interaction partners for Nek4.1 and Nek4.2 isoforms: from the DNA damage response to RNA splicing.

TRAK2 HECTD1 OMG EMSY PCNA

6.95e-0451348525798074
Pubmed

Evidence for significant overlap between common risk variants for Crohn's disease and ankylosing spondylitis.

MUC19 EMSY

8.45e-043148221072187
Pubmed

Tbx3 controls the sinoatrial node gene program and imposes pacemaker function on the atria.

TBX3 PCNA

8.45e-043148217473172
Pubmed

BioID identifies novel c-MYC interacting partners in cultured cells and xenograft tumors.

MLH1 KMT2A MGA

8.52e-0413448325452129
Pubmed

Molecular mapping of developing dorsal horn-enriched genes by microarray and dorsal/ventral subtractive screening.

TSHZ3 AJAP1

9.01e-043248216516881
Pubmed

Tbx3 controls the fate of hepatic progenitor cells in liver development by suppressing p19ARF expression.

TBX3 PCNA

9.58e-043348218356246
Pubmed

Hepatocyte nuclear factor 4alpha is essential for embryonic development of the mouse colon.

MUC17 MUC4

9.58e-043348216618389
Pubmed

The E3 ubiquitin ligases, HUWE1 and NEDD4-1, are involved in the post-translational regulation of the ABCG1 and ABCG4 lipid transporters.

HUWE1 HECTD1

9.58e-043348226296893
Pubmed

Genome-wide contribution of genotype by environment interaction to variation of diabetes-related traits.

NRG3 MAP3K1

9.58e-043348224204828
Pubmed

The splicing regulator Rbfox2 is required for both cerebellar development and mature motor function.

HUWE1 LRP8

9.58e-043348222357600
InteractionFEV interactions

NCOA2 KMT2A ATF1 TAF6 MGA EMSY

5.70e-06203456int:FEV
InteractionELF1 interactions

KMT2A ATF1 TAF6 MGA EMSY

8.82e-06126455int:ELF1
InteractionCA2 interactions

KMT2A HUWE1 USP42 PCNA

2.23e-0574454int:CA2
Cytoband7q22

MUC3B ZAN MUC3A

8.82e-06384837q22
CytobandEnsembl 112 genes in cytogenetic band chr7q22

TAF6 ZAN MUC17 MUC3A

8.31e-05219484chr7q22
GeneFamilyCD molecules|Mucins

MUC19 MUC16 MUC5B MUC3B MUC22 MUC17 MUC3A MUC4

5.59e-1821318648
GeneFamilyT-boxes

TBX3 MGA

4.28e-0418312766
CoexpressionNABA_ECM_AFFILIATED

MUC19 OPRPN MUC16 MUC5B MUC22 MUC17 MUC3A MUC4

6.73e-10170478M5880
CoexpressionNABA_MATRISOME_ASSOCIATED

MUC19 OPRPN MUC16 MUC5B NRG3 MUC22 MUC17 MUC3A MUC4

6.37e-06751479M5885
CoexpressionNABA_ECM_AFFILIATED

MUC19 MUC16 MUC5B MUC17 MUC4

9.34e-06158475MM17063
CoexpressionNABA_MATRISOME

MUC19 OPRPN MUC16 MUC5B NRG3 MUC22 MUC17 MUC3A MUC4

7.43e-051026479M5889
CoexpressionTHAKAR_PBMC_INACTIVATED_INFLUENZA_AGE_21_30YO_NONRESPONDER_7DY_UP

SCYL2 TRAK2 TMEM123 MAP3K1

7.98e-05127474M40905
CoexpressionBROWNE_HCMV_INFECTION_8HR_DN

NAV3 SPN LRP8

8.83e-0548473M7846
ToppCellnucseq-Epithelial-Epithelial_Glandular|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MUC16 MUC5B MUC17 MUC3A MUC4 MGAM2

3.42e-08179476859cd8ee414ad6207c046ada2e655e49322dd01c
ToppCellnucseq-Epithelial-Epithelial_Glandular-Goblet|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MUC16 MUC5B MUC17 MUC3A MUC4 MGAM2

3.53e-081804763dc80bc636bf0e6ffc9762853132a9fe59fd1f66
ToppCellnucseq-Epithelial-Epithelial_Glandular-Goblet-Goblet|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MUC16 MUC5B MUC17 MUC3A MUC4 MGAM2

3.53e-08180476668a2d8e1d5a390309d5eb62c836f5903144bea9
ToppCellControl-Epithelial_cells-Airway_mucous|Control / group, cell type (main and fine annotations)

MUC16 MUC5B MUC17 MUC3A MUC4 MGAM2

3.90e-0818347615d24a4fb1ffe6cbafbd54fcd7dde9ddcfbe03b2
ToppCellControl-Epithelial_cells-Airway_goblet|Control / group, cell type (main and fine annotations)

MUC16 MUC5B MUC17 MUC3A MUC4 MGAM2

4.03e-08184476d92a71441e4e19f8c301999d8186f8e48e3cd162
ToppCellCOVID-19-kidney-Glomerular_EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

TBX3 NRG3 AJAP1 ADGRL2 MTSS1

1.87e-06194475660535b492445063d965095a50e1e299ce04c50a
ToppCelldroplet-Lung-LUNG-30m-Myeloid-Neutrophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MUC5B MUC4 VASP STON2

2.56e-05162474dddf7a3901ae59e3494d8a6740db0fa15cc96d47
ToppCelldroplet-Lung-LUNG-30m-Myeloid-neutrophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MUC5B MUC4 VASP STON2

2.56e-051624742a4e09545e9874519f0f56e81065104987d81cd6
ToppCellAdult-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D231|Adult / Lineage, Cell type, age group and donor

TBX3 NRG3 AJAP1 ADGRL2

2.88e-051674745af9127bae05768a5164d5708a4ad37edca99324
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TBX3 NRG3 ADGRL2 MTSS1

3.02e-05169474987ff79ad563825dd9877ea8ccb536758f8c6700
ToppCellAdult-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D122|Adult / Lineage, Cell type, age group and donor

TBX3 NRG3 AJAP1 ADGRL2

3.16e-05171474bd20e85d36fa9d7ddc8afef6a1dea75efc9ee1dc
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell_prolif|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TBX3 NRG3 ADGRL2 MTSS1

3.31e-05173474f193c63cc536d891c9d23043765e320252bb6e65
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC16 MUC3A MUC4 LRP8

3.39e-05174474207aa0118633cbe9a65839bbb1bb3ba9f8118ad2
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Myeloid_monocytic-classical_monocyte-Classical_monocytes-Classical_monocytes_L.1.2.4.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TSHZ3 MUC5B CCNB3 CD300A

3.39e-05174474b6e3fa995def40a8fbdfc249fe108c303931a171
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MUC19 POM121L2 NRG3 ADGRL2

3.78e-05179474d3438fed0d85d5ed5afa8ff820c45143d77b6c0d
ToppCellControl-Endothelial_cells-Capillary_endothelial_cells|Control / group, cell type (main and fine annotations)

TBX3 NRG3 AJAP1 ADGRL2

3.86e-05180474b043f9ffb9a4cd427a15bebb86a711c7b08866e8
ToppCellCiliated_cells-A-Donor_07|World / lung cells shred on cell class, cell subclass, sample id

MUC16 MUC5B MUC4 OMG

3.86e-05180474d9be152773fe9f2160edad9246fa03c03afeafd6
ToppCellCOVID-19-Endothelial_cells-Capillary_endothelial_cells|COVID-19 / group, cell type (main and fine annotations)

TBX3 NRG3 AJAP1 ADGRL2

3.95e-05181474c5f9c92af1384d9089c65afdf41c6feb8345a3ae
ToppCellAdult-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D175|Adult / Lineage, Cell type, age group and donor

TBX3 NRG3 AJAP1 ADGRL2

4.03e-051824748b4a07ebd7a133a33ef333cfa29d12c4f3d4d9ac
ToppCellCiliated_cells-A-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

MUC16 MUC5B MUC4 OMG

4.21e-0518447407c5a9633ccdcd18771e3230d6198a55c400afa6
ToppCellAdult-Endothelial-capillary_endothelial_cell_(Cap1)-D231|Adult / Lineage, Cell type, age group and donor

NAV3 TBX3 NRG3 ADGRL2

4.30e-0518547407f9f38f0739d7c830641723a38385550ac1ac92
ToppCellAdult-Immune-interstitial_macrophage_(C1Q_positive)-D175|Adult / Lineage, Cell type, age group and donor

TSHZ3 MAP3K1 MTSS1 STON2

4.30e-05185474ab5704b96f1d368911308797d10c7c52766ab134
ToppCellAdult-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)|Adult / Lineage, Cell type, age group and donor

TBX3 NRG3 AJAP1 ADGRL2

4.58e-05188474e5cad03f4a64147fe8174e7f614cf45233ffb9b7
ToppCellsystemic_lupus_erythematosus-flare-Myeloid-non-classical_monocyte-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

SPN VASP CD300A MTSS1

4.58e-051884743e94d105ca96ceb5fdcca39a8050217913bc02da
ToppCellsaliva-Severe-critical_progression_d12-22_with-steroid-Lymphocytic|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

MLH1 ATF1 TAF6 NPAP1

4.77e-05190474373629dde5eda722424c5e6087763f0c5db67cf4
ToppCellILEUM-non-inflamed-(7)_Endothelial_cell-(7)_Lymphatics|(7)_Endothelial_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

OMG MAP3K1 MTSS1 STON2

4.77e-051904749ce301841ce9486701fa28eb2a9929e35d476878
ToppCellfacs-Marrow-B-cells-18m-Lymphocytic-immature_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCPEP1 TMEM123 MAP3K1 MTSS1

4.87e-0519147410644258b97f9c99eb0e199b64b970f6b986aa41
ToppCellfacs-Marrow-B-cells-18m-Lymphocytic-immature_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCPEP1 TMEM123 MAP3K1 MTSS1

4.87e-05191474408942fc8db939239aeee6ae07a21362133c9e2e
ToppCellfacs-Marrow-T-cells-3m-Lymphocytic-immature_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM123 MED13 MAP3K1 MTSS1

4.97e-051924742de242d81dc085ae734eb7d1f091af9a542e0866
ToppCellfacs-Marrow-T-cells-3m-Lymphocytic-immature_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM123 MED13 MAP3K1 MTSS1

4.97e-05192474ba2a683472a8b785dbf666dc6e94356d879486c3
ToppCellnormal-na-Myeloid-non-classical_monocyte-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

SPN VASP CD300A MTSS1

5.07e-05193474053adc7ed9f997b503e12239a684bb9f5896e10c
ToppCellTCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6|TCGA-Prostate / Sample_Type by Project: Shred V9

HUWE1 MGA HECTD1 MED13

5.07e-05193474abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCellnucseq-Endothelial-Endothelial_Vascular-Endothelial_capillary-CAP1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

NAV3 TBX3 NRG3 ADGRL2

5.07e-05193474ad3f4fcc8e2816d696cbcde744dc16500e51ccac
ToppCellfacs-Marrow-B-cells-3m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM123 MED13 MAP3K1 MTSS1

5.07e-0519347424c34c6635eb7fc2878282803c421b64320e77d8
ToppCellfacs-Marrow-B-cells-3m-Lymphocytic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM123 MED13 MAP3K1 MTSS1

5.17e-051944747ee8ac172c2dee7df7dc4eb222e0985a0089bda8
ToppCellCOPD-Endothelial-VE_Capillary_B|COPD / Disease state, Lineage and Cell class

NAV3 TBX3 NRG3 ADGRL2

5.17e-0519447418b7f901c12ca4f21f9a1eafd092aefe4d668b6d
ToppCellBLOOD--(3)_MNP-(3)_Non_classical_monocytes|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

SPN VASP CD300A MTSS1

5.17e-05194474f80433c7dd7590ca8c49630d2cd018b63438fd92
ToppCellmyeloid-CD16+_Monocyte|myeloid / Lineage and Cell class

SPN VASP CD300A MTSS1

5.17e-05194474aeeadfeb01827dbc7de6576c76fb2e41a3c59247
ToppCellCOPD-Endothelial-VE_Capillary_B|World / Disease state, Lineage and Cell class

NAV3 TBX3 NRG3 ADGRL2

5.17e-0519447468705a6eca947c5b42b943d5224a7aef2a744007
ToppCellfacs-Marrow-B-cells-3m-Lymphocytic-immature_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM123 MED13 MAP3K1 MTSS1

5.27e-05195474d77423d0ec64b397c6d1eec181c5fc0acaa92d63
ToppCellSmart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

MUC19 MUC16 MUC3A VASP

5.27e-05195474d3755929ebbbf5e3afde44281e9056ddb614a291
ToppCellIIF-Myeloid-CD16_Mono|IIF / Disease, Lineage and Cell Type

SPN VASP CD300A MTSS1

5.27e-0519547487c1f52ab19b105bae3f315496c620c226a77a7f
ToppCellfacs-Marrow-B-cells-3m-Lymphocytic-immature_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM123 MED13 MAP3K1 MTSS1

5.27e-05195474f5bf4797972185afa76638293166abd536e5472f
ToppCellSmart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

MUC19 MUC16 MUC3A VASP

5.27e-0519547419853c654ac64b3ae3bc99841c6cb29c8aaba85c
ToppCellControl-Non-classical_Monocyte-|Control / Disease condition and Cell class

SPN VASP CD300A MTSS1

5.38e-05196474b17ab094cdc7050c2997e24ed474779b5d6f6146
ToppCell15-Trachea|15 / Age, Tissue, Lineage and Cell class

MUC16 MUC5B MUC4 OMG

5.38e-05196474fd17403422cf95c24f6be1c2d78764bb352f7f2e
ToppCellCOVID-19-lung-Capillary_Aerocytes|COVID-19 / Disease (COVID-19 only), tissue and cell type

TBX3 NRG3 AJAP1 ADGRL2

5.38e-0519647449cc0a2b9739abad61dff7292ea0b14d28ff35c4
ToppCellControl-Non-classical_Monocyte|Control / Disease condition and Cell class

SPN VASP CD300A MTSS1

5.38e-05196474404064ccfe2cb73df7a7f88aa65d86b97dcef9d4
ToppCellCOVID-19-lung-Capillary_Aerocytes|lung / Disease (COVID-19 only), tissue and cell type

TBX3 NRG3 AJAP1 ADGRL2

5.38e-051964744ac4073380d939a73cec7413e9f3f5ef616d2924
ToppCellsystemic_lupus_erythematosus-treated-Myeloid-non-classical_monocyte|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

SPN VASP CD300A MTSS1

5.49e-051974741a82e0e74fc5fd71c490d98e8813d719b0b81aa6
ToppCellURO-Myeloid-CD16_Mono|URO / Disease, Lineage and Cell Type

SPN VASP CD300A MTSS1

5.49e-051974740201ba77419487e75edd5ea07ad7e5cbe87757d4
ToppCellsystemic_lupus_erythematosus-flare-Myeloid-non-classical_monocyte-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

SPN VASP CD300A MTSS1

5.49e-051974741463522df1b6358cbe3b5022a3e153878e9c9e43
ToppCellsystemic_lupus_erythematosus-treated-Myeloid-non-classical_monocyte-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

SPN VASP CD300A MTSS1

5.49e-0519747446d8c7e9b3aff70bc58894282d0ec9e87d37235f
ToppCellnormal-na-Myeloid-non-classical_monocyte-female|normal / PBMC cell types (v2) per disease, treatment status, and sex

SPN VASP CD300A MTSS1

5.60e-05198474d91bd26e499637949768587603cad3c03dcc56e7
ToppCellICU-SEP-Myeloid-CD16_Mono|ICU-SEP / Disease, Lineage and Cell Type

SPN VASP CD300A MTSS1

5.60e-051984743e6f262ec71e99a5dadbaaeaff1b4f1894907c7d
ToppCellsystemic_lupus_erythematosus-managed-Myeloid-non-classical_monocyte-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

SPN VASP CD300A MTSS1

5.60e-05198474ad8d4ad042f06fd1afbaef903fb36e57e4d23a7c
ToppCellsystemic_lupus_erythematosus-flare-Myeloid-non-classical_monocyte|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

SPN VASP CD300A MTSS1

5.60e-0519847411b0d021114df73a539b04f76dd7c63f1fdbdf4f
ToppCellsystemic_lupus_erythematosus-managed-Myeloid-non-classical_monocyte-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

SPN VASP CD300A MTSS1

5.60e-051984748de49c62ab533031936db4cee50ff13b259ecc22
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TBX3 NRG3 ADGRL2 MTSS1

5.60e-0519847492416e65a0dc1a4bf931833407620ea05d362f56
ToppCellnormal-na-Myeloid-non-classical_monocyte|normal / PBMC cell types (v2) per disease, treatment status, and sex

SPN VASP CD300A MTSS1

5.60e-05198474f5a12861e2b8ff8309f3e4d0ad83d4f6860cc616
ToppCellsystemic_lupus_erythematosus-managed-Myeloid-non-classical_monocyte|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

SPN VASP CD300A MTSS1

5.60e-0519847460e5bd8dfe27c43ce5f4da19b65270c41577ef4f
ToppCellCOVID-19_Convalescent-Non-classical_Monocyte-|COVID-19_Convalescent / Disease condition and Cell class

SPN VASP CD300A MTSS1

5.71e-05199474996a207b8b91e10dd018dc07aaf5ecd473bfeaad
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW13-Stem_cells|GW13 / Sample Type, Dataset, Time_group, and Cell type.

NCOA2 MLH1 NBAS PCNA

5.71e-05199474fd1d1b95e01719e3d0a17d9d1f29717a47209d32
ToppCellParenchymal-NucSeq-Endothelial-Endothelia_vascular-VE_alveolar_capillary_Car4_aerocyte|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TBX3 NRG3 AJAP1 ADGRL2

5.71e-05199474dc88ce36cc066eb6c28cfd5b9b60fe07f8cc7b53
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW13-Stem_cells-Stem_cells|GW13 / Sample Type, Dataset, Time_group, and Cell type.

NCOA2 MLH1 NBAS PCNA

5.71e-0519947491882af9dc7265c9b419f4415cbcf656087a2ab3
ToppCellCOVID-19_Convalescent-Non-classical_Monocyte|COVID-19_Convalescent / Disease condition and Cell class

SPN VASP CD300A MTSS1

5.71e-05199474c9250c80dd5bc3d27c6065b99119ff7dcf392e84
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW13-Stem_cells|GW13 / Sample Type, Dataset, Time_group, and Cell type.

NCOA2 MLH1 NBAS PCNA

5.82e-05200474d933978b55fefe52cad599b36f6b47a0c7f71f96
ToppCellLeuk-UTI-Myeloid-CD16_Mono|Leuk-UTI / Disease, Lineage and Cell Type

SCPEP1 VASP CD300A MTSS1

5.82e-05200474ea5cd46031c7e8604387be2a82a1d59022458632
ToppCellTracheal-10x5prime-Immune_Myeloid-Monocytic-Monocyte_CD16|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

SPN CD300A MAP3K1 MTSS1

5.82e-052004745ea3e74687893b8ca6cb915f0f14a14d4692775c
ToppCellLung_Parenchyma-Severe|Lung_Parenchyma / Location, Disease Group, Cell group, Cell class (2021.03.09)

MUC16 MUC5B MUC4 OMG

5.82e-0520047462502bb23ca732daed32c838ce9719093f3aaeb0
ToppCellMS-IIF-Myeloid-CD16+_Monocyte|IIF / Disease, condition lineage and cell class

SPN VASP CD300A MTSS1

5.82e-05200474c6245c24a5e7c550d06a3b2f180773638f9f3a4a
ToppCellSepsis-ICU-SEP-Myeloid-CD16+_Monocyte|ICU-SEP / Disease, condition lineage and cell class

SPN VASP CD300A MTSS1

5.82e-05200474de39d94af8ef489ea347b6ecf1a39e7849f2f72e
ToppCellNS-control|NS / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

MUC16 SCPEP1 HECTD1 MUC4

5.82e-05200474ecbe89ff95d046155b984c8c150e0b9e7278f839
ToppCellSepsis-URO-Myeloid-CD16+_Monocyte|URO / Disease, condition lineage and cell class

SPN VASP CD300A MTSS1

5.82e-0520047482408dac860899510a1f5849d2b0b1692053fb96
ToppCellBronchial-NucSeq-Endothelial-Endothelia_vascular-VE_alveolar_capillary_Car4_aerocyte|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TBX3 NRG3 AJAP1 ADGRL2

5.82e-05200474105c67e4f5eff036013d655c8e8ac577d32dae2e
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW13-Stem_cells-Neuroepithelial_cell|GW13 / Sample Type, Dataset, Time_group, and Cell type.

NCOA2 MLH1 NBAS PCNA

5.82e-052004743d932765c31aef1f80a118d51e8e66c50a758dbb
ToppCellSepsis-Leuk-UTI-Myeloid-CD16+_Monocyte|Leuk-UTI / Disease, condition lineage and cell class

SCPEP1 VASP CD300A MTSS1

5.82e-05200474f4abe8b693db9e3d955b2529a8f848cb0459e900
ToppCellPosterior_cortex-Macroglia-OLIGODENDROCYTE-O2-Tfr-Oligodendrocyte.Tfr.Sez6_(Sez6)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

ZAN MUC4 STON2

7.12e-05764732b1d7bafad3d9a01fc47790418160950330576c5
ToppCellPosterior_cortex-Macroglia-OLIGODENDROCYTE-O2-Tfr-Oligodendrocyte.Tfr.Sez6_(Sez6)-|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

ZAN MUC4 STON2

7.12e-0576473322c3a4c3abdc419f162861ecd52c0ad6ef2381c
ToppCellMyeloid-Myeloid-C_(Cd16+_Monocyte)|Myeloid / shred on cell class and cell subclass (v4)

NCOA2 SPN CD300A

2.56e-04117473d1936e76a935216783a73ab414e4147fa48e68eb
ToppCellNS-moderate-d_07-13-Epithelial-unknown_epithelial|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

MUC16 MUC4 STON2

3.48e-041304731491e8975520e99c527a5b5bee64875d124f7bf4
ToppCell343B-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

TBX3 AJAP1 ADGRL2

4.24e-041394732fdc8f36510aff24abbc79ef2a842db75a85f946
ToppCell343B-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

TBX3 AJAP1 ADGRL2

4.24e-041394735970a654c64e3b54f9d18c102f5b125eec892fc5
ToppCellNS-critical-d_07-13-Epithelial-unknown_epithelial|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

MUC16 DSC1 MUC4

4.42e-0414147333ad925ff7be3c682741a6328216a89f9d4033e9
ToppCellfacs-Marrow-B-cells-24m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HAVCR1 DSC1 LRP8

4.60e-041434736df16bf0324661cd9707df69cb39f4b5498d6d49
ToppCellfacs-Marrow-B-cells-24m-Myeloid-CD4+_macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HAVCR1 DSC1 LRP8

4.99e-041474739d7e965fe61bd7b31e09c4b2129a5a98c36f4811
ToppCellfacs-Marrow-B-cells-24m-Myeloid-macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HAVCR1 DSC1 LRP8

4.99e-0414747338552953ff65a0fc20bee6ef57dc5885306ad18b
ToppCellpdx-Tumor_cells-T4|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

MUC16 DSC1 MUC4

5.50e-041524737ccc56b79c499dd48dab8e2d936edca5223b9356
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MUC16 HAVCR1 NRG3

5.60e-04153473499670e716fc85ce76630fc813cec86f8419f2a1
ToppCellPND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD4_T-CD4_T_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SPN PCNA LRP8

5.60e-041534730ad401cb70b9edfc6ae6ccba6879c6c2b6c4d296
ToppCelldroplet-Fat-SCAT-30m-Myeloid-monocyte|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MLH1 SPN CD300A

5.60e-041534732731c3d4ac40ecc22108f8f3f45a069077159125
ToppCell(6)_Endothelial_cells-(6)_Endothelial-C_(Capillary_Aerocyte_)|(6)_Endothelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)

TBX3 AJAP1 ADGRL2

6.04e-0415747384f629b7f589ca8a1abc220fa740c4a6fdc1b579
ToppCellfacs-Marrow-KLS-24m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSHZ3 SPN STON2

6.04e-04157473662d5026e0e4249029fc6f3abc771d775d7bc3bb
ToppCellfacs-Marrow-KLS-24m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSHZ3 SPN STON2

6.04e-041574733c6be6995c00c4cadbd209c66bf9a87c8c238652
ToppCell367C-Lymphocytic-NK_cells-NK_cell_B|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

SPN OMG MTSS1

6.15e-041584731bf692f1e85f677cd62805437b7a59cfaf3b0449
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC16 MUC5B MUC4

6.27e-0415947360b1f4dce2ce0911160fda17f137c064da31e2eb
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-myeloid-myeloid_macrophage-microglial_cell|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

NAV3 OPRPN MUC22

6.27e-0415947331ec8222c766cb614e1cf27f74ee9d99489eca5c
ToppCellfacs-Liver-Non-hepatocytes-3m-Myeloid-myeloid_leukocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HAVCR1 CD300A LRP8

6.38e-04160473237430af14830b38e58da8a4224036e5c6b71c5b
ToppCellChildren_(3_yrs)-Epithelial-lung_goblet_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

MUC16 MUC5B MUC4

6.50e-041614732d63b279d9a5132e1c09b03930bf9039036d24a2
ToppCelldroplet-Lung-30m-Hematologic-myeloid-neutrophil|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MUC5B MUC4 VASP

6.61e-041624739c9a63adb692651ea5a52cc77b02c5ce11d0ccea
Drugcellobiitol

MUC3B SPN MUC3A MUC4

9.17e-0737464CID000003871
DrugTn epitope

MUC3B SPN MUC3A MUC4

4.61e-0655464CID000447272
Druggeldanamycin

SCYL2 NCOA2 KMT2A NBAS HECTD1 MED13 MAP3K1

8.93e-06371467ctd:C001277
Drugmucic acid

HAVCR1 MUC3B SPN MUC3A

3.00e-0588464CID000000607
Drugrioprostil

MUC3B SPN MUC3A

3.67e-0532463CID005311413
Drug(-) -Levobunolol hydrochloride [27912-14-7]; Down 200; 12.2uM; MCF7; HT_HG-U133A

NCOA2 OPRPN POM121L2 TBX3 VASP

4.40e-051944654134_DN
DrugLasalocid sodium salt [25999-20-6]; Up 200; 6.6uM; MCF7; HT_HG-U133A

POM121L2 TBX3 MUC5B AJAP1 MAP3K1

4.62e-051964653360_UP
DrugAlcuronium chloride [15180-03-7]; Down 200; 5.4uM; MCF7; HT_HG-U133A

NCOA2 MUC5B AJAP1 SPN MAP3K1

4.62e-051964654409_DN
DrugPrimidone [125-33-7]; Down 200; 18.4uM; HL60; HT_HG-U133A

POM121L2 HUWE1 SPN OMG MTSS1

4.74e-051974653065_DN
DrugMedrysone [2668-66-8]; Up 200; 11.6uM; MCF7; HT_HG-U133A

HUWE1 SPN MUC4 OMG CD300A

4.97e-051994653603_UP
Diseasecholangiocarcinoma (is_marker_for)

MUC16 MUC5B MUC3A MUC4

3.35e-0664474DOID:4947 (is_marker_for)
Diseasemucositis (biomarker_via_orthology)

MUC4 PCNA

2.48e-055472DOID:0080178 (biomarker_via_orthology)
DiseaseProstatic Neoplasms

NCOA2 MLH1 KMT2A TBX3 MGA MUC4 MAP3K1

5.09e-05616477C0033578
DiseaseMalignant neoplasm of prostate

NCOA2 MLH1 KMT2A TBX3 MGA MUC4 MAP3K1

5.09e-05616477C0376358
Diseasecocaine use disorder, social environment measurement

TRAK2 ADGRL2

6.91e-058472EFO_0010445, EFO_0010552
Diseaseotitis media (is_marker_for)

MUC5B MUC4

1.11e-0410472DOID:10754 (is_marker_for)
DiseaseMalignant neoplasm of stomach

MLH1 KMT2A NBAS TBX3 MTSS1

1.14e-04300475C0024623
Diseasepancreatic ductal carcinoma (is_marker_for)

MUC5B MUC3A MUC4

1.28e-0461473DOID:3587 (is_marker_for)
Diseasemalignant pleural mesothelioma (is_marker_for)

NCOA2 MLH1

2.23e-0414472DOID:7474 (is_marker_for)
Diseasecolorectal cancer

MLH1 SCPEP1 TBX3 ATF1 NRG3 MUC22

3.78e-04604476MONDO_0005575
Diseasesystemising measurement

NBAS TSHZ3

5.12e-0421472EFO_0010221
DiseaseSjogren's syndrome (is_marker_for)

MUC19 MUC16

6.70e-0424472DOID:12894 (is_marker_for)
DiseaseRS-10-hydroxywarfarin to RS-warfarin ratio measurement

SCPEP1 MUC3B MUC3A

7.25e-04110473EFO_0803335
Diseasebreast cancer, lung cancer

POM121L2 MAP3K1

7.28e-0425472MONDO_0007254, MONDO_0008903
DiseaseHyalinosis, Segmental Glomerular

HAVCR1 PCNA

9.14e-0428472C0086432
Diseasestimulant use measurement

NCOA2 NBAS

9.14e-0428472EFO_0600076
Diseaseeicosapentaenoic acid measurement

TSHZ3 MUC22

1.12e-0331472EFO_0007760
Diseaserenal cell carcinoma (is_marker_for)

MLH1 HAVCR1 PCNA

1.12e-03128473DOID:4450 (is_marker_for)
DiseaseHereditary Diffuse Gastric Cancer

KMT2A NBAS TBX3 MTSS1

1.21e-03293474C1708349
DiseaseStomach Neoplasms

KMT2A NBAS TBX3 MTSS1

1.28e-03297474C0038356
Diseasediet measurement

SCYL2 NBAS POM121L2 NRG3 ADGRL2 MUC17 STON2

1.28e-031049477EFO_0008111
Diseaseglomerular filtration rate, renal transplant outcome measurement

NBAS ADGRL2

1.43e-0335472EFO_0005199, EFO_0005208
Diseaseanti-GAD65 autoimmune neurological syndromes

ZAN MUC22

1.43e-0335472EFO_0803379
DiseaseFocal glomerulosclerosis

HAVCR1 PCNA

1.51e-0336472C0017668
Diseasestomach cancer (is_marker_for)

NCOA2 TBX3 PCNA

1.52e-03142473DOID:10534 (is_marker_for)
Diseasediabetic nephropathy

NAV3 ADGRL2 LRP8

1.77e-03150473EFO_0000401
Diseasecolorectal cancer, colorectal adenoma

TBX3 ATF1 MUC22

1.84e-03152473EFO_0005406, MONDO_0005575
Diseaseheart rate response to exercise

MUC3B MUC3A

2.15e-0343472EFO_0009184
DiseaseProteinuria

MUC16 HAVCR1

2.15e-0343472C0033687
Diseaseesophagus squamous cell carcinoma (is_implicated_in)

MLH1 MAP3K1

2.35e-0345472DOID:3748 (is_implicated_in)
Diseasemultiple sclerosis symptom measurement

NCOA2 MTSS1

2.46e-0346472EFO_0803536
Diseaseprimary ovarian insufficiency (implicated_via_orthology)

MLH1 USP42

2.46e-0346472DOID:5426 (implicated_via_orthology)
Diseaseserum gamma-glutamyl transferase measurement

MLH1 KMT2A ADGRL2 OMG MED13 EMSY

3.16e-03914476EFO_0004532
Diseaseamino acid measurement

NAV3 NBAS NRG3 ADGRL2 MGAM2

4.37e-03678475EFO_0005134

Protein segments in the cluster

PeptideGeneStartEntry
VAATTTTTTTATPMT

AJAP1

216

Q9UKB5
TTTTTATPMTLQTKG

AJAP1

221

Q9UKB5
TIISTTSTTSQKGPM

ADGRL2

416

O95490
SSIATMTSVGKSRTT

CCNB3

1071

Q8WWL7
TTTTTTVATGSMATP

MUC5B

2106

Q9HC84
TKATTTRATSSMSTP

MUC5B

3111

Q9HC84
TTTTTVATGSMATPS

MUC5B

3921

Q9HC84
FPKAMETTTTTTSTT

NRG3

121

P56975
STSATSLSATVMVSK

MUC16

986

Q8WXI7
TSIASSTMDVTKTAS

MUC16

2376

Q8WXI7
STMDVTKTASISPTS

MUC16

2381

Q8WXI7
TKTASISPTSISGMT

MUC16

2386

Q8WXI7
TITTMGTNSISTTTP

MUC16

3541

Q8WXI7
SPVSMSSVLTSSLVK

MUC16

4771

Q8WXI7
TTVSTSMSVSSETTK

MUC16

6926

Q8WXI7
STSPIKTESTEMTIT

MUC16

9066

Q8WXI7
TSMMTSEKITVTTST

MUC4

256

Q99102
TTRSVSPMTDTKTVT

MUC4

651

Q99102
TTMPSPTSSTTVSTI

MGAM2

2081

Q2M2H8
ATVTTTSTKDNTMSP

MGAM2

2356

Q2M2H8
VTAAASSSMVTTPTS

MGA

1701

Q8IWI9
TSEPLSSKMYTTSIT

SPN

36

P16150
TTVPETTMASSTTST

MUC22

146

E2RYF6
TKATPLSSTVTLSMS

PCNA

216

P12004
SSPSTTMSRKSSVCS

MTSS1

261

O43312
ASGMTGVTTTTKTTT

MUC19

7096

Q7Z5P9
TFTVSSSSAMSTSVI

MUC3A

471

Q02505
APTTTTSFTTSTTME

MUC3A

571

Q02505
STSMISSTVSTGIPT

MUC3A

806

Q02505
VTSTTMTPSSLSTDT

MUC3A

1181

Q02505
VSSSSAMSTSVIPSS

MUC3A

1226

Q02505
ITSVPTTLGTMVTST

MUC3A

1546

Q02505
TMLTVKQSSTATSPT

NAV3

346

Q8IVL0
TTTVSISPTTKGSKS

HUWE1

3541

Q7Z6Z7
TATTMKVLSNTTTTT

NBAS

1411

A2RRP1
SSNTTVTTMKPTAAS

TMEM123

81

Q8N131
NMTSTTLKSTPKTTS

TMEM123

106

Q8N131
TPGTTSTVTMSTSSV

HECTD1

1601

Q9ULT8
ASSQTPTMCTTTVTV

DSC1

446

Q08554
KIQLTSSVSSTPSVM

KMT2A

3101

Q03164
SGTTTKITTIPMTSK

EMSY

561

Q7Z589
TSTTTLASTMTRTVP

LRP8

741

Q14114
MPVSTTVVASSAIST

MUC17

2166

Q685J3
MPVSTTTVASSETST

MUC17

3286

Q685J3
TMTTRTKPSTRTTSF

MUC17

4091

Q685J3
STNTVTSMTTTTSRP

MUC3B

266

Q9H195
TSMTTTTSRPTATNT

MUC3B

271

Q9H195
SSLVGTTSPTMSTVR

MUC3B

451

Q9H195
STTTTTTTTEQPKPM

MAP3K1

941

Q13233
TKFIVMSSSSSAPST

TAF6

536

P49848
SSTLSSSSMSLSPKL

TBX3

696

O15119
NILTKSTPTSTMESS

SCPEP1

271

Q9HB40
SIPTTTTVLTTMTVS

HAVCR1

171

Q96D42
TMTVSTTTSVPTTTS

HAVCR1

181

Q96D42
NMSSLTSLSVSTPKS

SCYL2

726

Q6P3W7
ATATTSTSTKPTMTI

OPRPN

161

Q99935
STSTKPTMTISSSTV

OPRPN

166

Q99935
SSTMTVTSGVAISTS

MED13

1511

Q9UHV7
SGEMVKSTTSLTSSS

MLH1

356

P40692
SVITSKPMNSTSVIS

NPAP1

541

Q9NZP6
MVTNTSLTSSTKSSP

OMG

361

P23515
SVVMSTTLASTSKDS

POM121L2

621

Q96KW2
SMPTTSASKASVRSI

STON2

836

Q8WXE9
MTSPVTLTSQTTKTD

ATF1

196

P18846
MTPASITAAKTSTIT

CD300A

131

Q9UGN4
ISMTSVTSVPTSGLS

NCOA2

1411

Q15596
STTTFSSTMSLAKLL

TRAK2

731

O60296
TSNASTMSVSSKVTK

USP42

566

Q9H9J4
VMSPSSSKSTKSTST

SRRM5

56

B3KS81
TVTTAKTSAVVSFMS

TSHZ3

821

Q63HK5
TLPRMKSSSSVTTSE

VASP

316

P50552
MTSVILGTTTTSRSS

ZAN

1026

Q9Y493