Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcesspositive regulation of transcription by RNA polymerase II

HOXA5 HOXB1 ABLIM1 HIVEP2 TCF12 VGLL2 BCLAF1 ZNF335 GLIS3 KMT2A LRP5 TBXT DOT1L TFAP2B RXRG NOTCH1 TP73

9.31e-0713906517GO:0045944
GeneOntologyBiologicalProcesscell-cell signaling involved in mammary gland development

HOXA5 LRP5

9.78e-062652GO:0060764
GeneOntologyBiologicalProcessanterior/posterior pattern specification

HOXA5 HOXB1 FRS2 KMT2A LRP5 TBXT NOTCH1

1.25e-05247657GO:0009952
GeneOntologyCellularComponentmethyltransferase complex

KANSL1 ZC3H13 ZNF335 KMT2A VIRMA

2.16e-05108655GO:0034708
GeneOntologyCellularComponentRNA N6-methyladenosine methyltransferase complex

ZC3H13 VIRMA

3.38e-049652GO:0036396
GeneOntologyCellularComponentadherens junction

FRS2 SORBS1 CTNND2 FERMT2 NOTCH1

5.16e-04212655GO:0005912
GeneOntologyCellularComponentpostsynaptic specialization

TANC2 ABLIM1 GRID2IP KCND3 CTNND2 ELFN2 NOTCH1

9.34e-04503657GO:0099572
GeneOntologyCellularComponentmitotic spindle midzone

TTC28 CENPE

1.11e-0316652GO:1990023
DomainAT_hook

CECR2 KMT2A DOT1L

2.28e-0516663PF02178
Domainzf-RanBP

RANBP2 TAB3

2.71e-0322662PF00641
DomainZnF_RBZ

RANBP2 TAB3

2.97e-0323662SM00547
DomainZF_RANBP2_2

RANBP2 TAB3

2.97e-0323662PS50199
DomainZF_RANBP2_1

RANBP2 TAB3

3.23e-0324662PS01358
DomainANTENNAPEDIA

HOXA5 HOXB1

3.23e-0324662PS00032
DomainZnf_RanBP2

RANBP2 TAB3

3.50e-0325662IPR001876
DomainAT_hook

KMT2A DOT1L

4.08e-0327662SM00384
DomainAT_hook_DNA-bd_motif

KMT2A DOT1L

4.08e-0327662IPR017956
DomainHMGI/Y_DNA-bd_CS

CECR2 DOT1L

5.35e-0331662IPR000637
Pubmed

The TRIM9/TRIM67 neuronal interactome reveals novel activators of morphogenesis.

TANC2 ZCCHC14 ABLIM1 NYAP2 R3HDM2 SORBS1 CTNND2 TAB3

9.95e-0921867833378226
Pubmed

Identification of Wilms' tumor 1-associating protein complex and its role in alternative splicing and the cell cycle.

BCLAF1 ZC3H13 VIRMA

1.36e-07667324100041
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

TANC2 CADM3 RANBP2 ABLIM1 NYAP2 KCND3 BCLAF1 ATG2B SORBS1 CTNND2 FERMT2 ELFN2 TAB3

2.29e-071139671336417873
Pubmed

Comprehensive identification of phosphorylation sites in postsynaptic density preparations.

TANC2 RANBP2 ABLIM1 BCLAF1 SORBS1 CTNND2 ELFN2

3.23e-0723167716452087
Pubmed

A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.

ZCCHC14 ABLIM1 HIVEP2 TCF12 SERTAD2 KMT2A TBXT TFAP2B DMBX1 RXRG

1.01e-06709671022988430
Pubmed

A census of human transcription factors: function, expression and evolution.

HOXA5 HOXB1 HIVEP2 TCF12 ZNF335 KMT2A TBXT TFAP2B DMBX1 RXRG TP73

1.22e-06908671119274049
Pubmed

Mesodermal defects and cranial neural crest apoptosis in alpha5 integrin-null embryos.

HOXB1 TBXT NOTCH1

3.06e-06156739334279
Pubmed

p73α1, a p73 C-terminal isoform, regulates tumor suppression and the inflammatory response via Notch1.

NOTCH1 TP73

3.66e-06267235617425
Pubmed

Distinct Responses to Menin Inhibition and Synergy with DOT1L Inhibition in KMT2A-Rearranged Acute Lymphoblastic and Myeloid Leukemia.

KMT2A DOT1L

3.66e-06267238892207
Pubmed

MLL-rearranged leukemia is dependent on aberrant H3K79 methylation by DOT1L.

KMT2A DOT1L

3.66e-06267221741597
Pubmed

DOT1L inhibition sensitizes MLL-rearranged AML to chemotherapy.

KMT2A DOT1L

3.66e-06267224858818
Pubmed

TCF12-regulated GRB7 facilitates the HER2+ breast cancer progression by activating Notch1 signaling pathway.

TCF12 NOTCH1

3.66e-06267239113057
Pubmed

Kindlin-2 controls angiogenesis through modulating Notch1 signaling.

FERMT2 NOTCH1

3.66e-06267237480504
Pubmed

T-cell lymphoblastic leukemia in early childhood presents NOTCH1 mutations and MLL rearrangements.

KMT2A NOTCH1

3.66e-06267219631984
Pubmed

The role of DOT1L in the maintenance of leukemia gene expression.

KMT2A DOT1L

3.66e-06267227151433
Pubmed

The molecular mechanics of mixed lineage leukemia.

KMT2A DOT1L

3.66e-06267226923329
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

TANC2 ZCCHC14 ABLIM1 HIVEP2 TTC28 KMT2A SORBS1 PAN3 VIRMA TAB3

5.69e-06861671036931259
Pubmed

Signaling by FGF4 and FGF8 is required for axial elongation of the mouse embryo.

HOXB1 TBXT NOTCH1

6.48e-061967322954964
Pubmed

An atlas of combinatorial transcriptional regulation in mouse and man.

HOXA5 HOXB1 HIVEP2 TCF12 CHAF1A SERTAD2 GLIS3 TFAP2B RXRG TP73

6.68e-06877671020211142
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

TANC2 ZCCHC14 HIVEP2 KANSL1 ZNF335 TMEM132A LRP5 PAPLN REV3L DOT1L NOTCH1

7.99e-061105671135748872
Pubmed

Evolutionarily conserved requirement of Cdx for post-occipital tissue emergence.

HOXA5 HOXB1 TBXT

8.87e-062167322675207
Pubmed

HEB-deficient T-cell precursors lose T-cell potential and adopt an alternative pathway of differentiation.

TCF12 NOTCH1

1.10e-05367221189289
Pubmed

Leukemic transformation by the MLL-AF6 fusion oncogene requires the H3K79 methyltransferase Dot1l.

KMT2A DOT1L

1.10e-05367223361907
Pubmed

Cooperative gene activation by AF4 and DOT1L drives MLL-rearranged leukemia.

KMT2A DOT1L

1.10e-05367228394257
Pubmed

Targeting DOT1L and HOX gene expression in MLL-rearranged leukemia and beyond.

KMT2A DOT1L

1.10e-05367226118503
Pubmed

Requirement for Dot1l in murine postnatal hematopoiesis and leukemogenesis by MLL translocation.

KMT2A DOT1L

1.10e-05367221398221
Pubmed

Molecular networks in FGF signaling: flotillin-1 and cbl-associated protein compete for the binding to fibroblast growth factor receptor substrate 2.

FRS2 SORBS1

1.10e-05367222235335
Pubmed

A higher-order configuration of the heterodimeric DOT1L-AF10 coiled-coil domains potentiates their leukemogenenic activity.

KMT2A DOT1L

1.10e-05367231527241
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

ZCCHC14 ABLIM1 KANSL1 TTC28 R3HDM2 SORBS1 VIRMA

1.36e-0540767712693553
Pubmed

Dissecting Wnt/beta-catenin signaling during gastrulation using RNA interference in mouse embryos.

HOXB1 TBXT NOTCH1

1.52e-052567315857914
Pubmed

Genomic analysis of gastrulation and organogenesis in the mouse.

HOXB1 TBXT DMBX1

1.72e-052667318061570
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

RANBP2 ABLIM1 KANSL1 BCLAF1 ZC3H13 CHAF1A ZNF335 KMT2A VIRMA

1.73e-0577467915302935
Pubmed

Reconstruction of phrenic neuron identity in embryonic stem cell-derived motor neurons.

HOXA5 PCDH11Y NOTCH1

1.93e-052767324496616
Pubmed

Why do cellular proteins linked to K63-polyubiquitin chains not associate with proteasomes?

TTC28 CENPE TMEM132A MUC16 DMBX1

1.99e-0517067523314748
Pubmed

Src-mediated phosphorylation converts FHL1 from tumor suppressor to tumor promoter.

BCLAF1 FERMT2

2.19e-05467229434030
Pubmed

Mutant p53 antagonizes p63/p73-mediated tumor suppression via Notch1.

NOTCH1 TP73

2.19e-05467231712410
Pubmed

DOT1L, the H3K79 methyltransferase, is required for MLL-AF9-mediated leukemogenesis.

KMT2A DOT1L

2.19e-05467221521783
Pubmed

MLL1 and DOT1L cooperate with meningioma-1 to induce acute myeloid leukemia.

KMT2A DOT1L

2.19e-05467226927674
Pubmed

Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.

ZCCHC14 ABLIM1 TCF12 ZC3H13 SERTAD2 GLIS3 TBXT DMBX1 IKZF5

2.42e-0580867920412781
Pubmed

Transcription factors expressed in olfactory bulb local progenitor cells revealed by genome-wide transcriptome profiling.

ABLIM1 BCLAF1 TFAP2B NOTCH1

2.96e-059167421194568
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

TANC2 HOXB1 NYAP2 TTC28 MUC16 REV3L CTNND2 VIRMA

3.09e-0563867831182584
Pubmed

The secretory protein Sec8 is required for paraxial mesoderm formation in the mouse.

TBXT NOTCH1

3.64e-0556729441674
Pubmed

Rescue of a Wnt mutation by an activated form of LEF-1: regulation of maintenance but not initiation of Brachyury expression.

TBXT NOTCH1

3.64e-05567211447280
Pubmed

Hox proteins have different affinities for a consensus DNA site that correlate with the positions of their genes on the hox cluster.

HOXA5 HOXB1

3.64e-0556727911971
Pubmed

Mesodermal development in mouse embryos mutant for fibronectin.

TBXT NOTCH1

3.64e-0556728906418
Pubmed

Restricted expression of homeobox genes distinguishes fetal from adult human smooth muscle cells.

HOXA5 HOXB1

3.64e-0556728570656
Pubmed

Germline genetic variation in an organic anion transporter polypeptide associated with methotrexate pharmacokinetics and clinical effects.

GLIS3 LRMDA

5.46e-05667219901119
Pubmed

Transcription factor gene AP-2 gamma essential for early murine development.

TBXT TFAP2B

5.46e-05667211940672
Pubmed

Zc3h13 Regulates Nuclear RNA m6A Methylation and Mouse Embryonic Stem Cell Self-Renewal.

ZC3H13 VIRMA

5.46e-05667229547716
Pubmed

Genetic architecture of the mouse hippocampus: identification of gene loci with selective regional effects.

HOXA5 RXRG

5.46e-05667212953790
Pubmed

Cloning of the gene for spinocerebellar ataxia 2 reveals a locus with high sensitivity to expanded CAG/glutamine repeats.

CHERP KCNN3

5.46e-0566728896557
Pubmed

Function of leukemogenic mixed lineage leukemia 1 (MLL) fusion proteins through distinct partner protein complexes.

KMT2A DOT1L

5.46e-05667221896721
Pubmed

NSD1 is essential for early post-implantation development and has a catalytically active SET domain.

HOXB1 TBXT

5.46e-05667212805229
Pubmed

Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.

TANC2 ABLIM1 CPNE1 SORBS1 CTNND2 ELFN2

5.65e-0534767617114649
Pubmed

BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.

RANBP2 ABLIM1 TTC28 BCLAF1 ATG2B FRS2 FERMT2 NOTCH1

6.42e-0570867839231216
Pubmed

Multiple epigenetic maintenance factors implicated by the loss of Mll2 in mouse development.

HOXB1 TBXT

7.63e-05767216540515
Pubmed

The enigma of the numb-Notch relationship during mammalian embryogenesis.

TBXT NOTCH1

7.63e-05767216508312
Pubmed

Histone and DNA methylation defects at Hox genes in mice expressing a SET domain-truncated form of Mll.

HOXA5 KMT2A

7.63e-05767216618927
Pubmed

The extracellular domain of Lrp5/6 inhibits noncanonical Wnt signaling in vivo.

LRP5 TBXT

7.63e-05767219056682
Pubmed

Impact of cytosine methylation on DNA binding specificities of human transcription factors.

HOXA5 HOXB1 TCF12 TBXT TFAP2B DMBX1 RXRG

8.52e-0554467728473536
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

ABLIM1 TTC28 BCLAF1 ATG2B KMT2A DOT1L TAB3

9.02e-0554967738280479
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

TANC2 RANBP2 ABLIM1 NYAP2 CENPE BCLAF1 SORBS1 CTNND2 VIRMA

9.35e-0596367928671696
Pubmed

Wnt3a plays a major role in the segmentation clock controlling somitogenesis.

TBXT NOTCH1

1.02e-04867212636920
Pubmed

Caudal regression in adrenocortical dysplasia (acd) mice is caused by telomere dysfunction with subsequent p53-dependent apoptosis.

TBXT NOTCH1

1.02e-04867219660449
Pubmed

Vertebrate homeobox gene nomenclature.

HOXA5 HOXB1 NOTCH1

1.04e-04476731358459
Pubmed

New insights into the role of Jmjd3 and Utx in axial skeletal formation in mice.

HOXA5 HOXB1 TBXT

1.26e-045067328188179
Pubmed

Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System.

HOXA5 TCF12 LRP5 RXRG NOTCH1

1.26e-0425167529031500
Pubmed

Dynamic expression patterns of the pudgy/spondylocostal dysostosis gene Dll3 in the developing nervous system.

HOXB1 NOTCH1

1.30e-04967211118901
Pubmed

SORBS2 is a genetic factor contributing to cardiac malformation of 4q deletion syndrome patients.

HOXB1 NOTCH1

1.30e-04967234099102
Pubmed

Human TOB, an antiproliferative transcription factor, is a poly(A)-binding protein-dependent positive regulator of cytoplasmic mRNA deadenylation.

CHAF1A PAN3

1.30e-04967217785442
Pubmed

Abnormalities of floor plate, notochord and somite differentiation in the loop-tail (Lp) mouse: a model of severe neural tube defects.

TBXT NOTCH1

1.30e-0496729545534
Pubmed

RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.

RANBP2 ABLIM1 TTC28 FRS2 TAB3

1.57e-0426367534702444
Pubmed

A higher-order complex containing AF4 and ENL family proteins with P-TEFb facilitates oncogenic and physiologic MLL-dependent transcription.

KMT2A DOT1L

1.63e-041067220153263
Pubmed

The RING finger protein MSL2 in the MOF complex is an E3 ubiquitin ligase for H2B K34 and is involved in crosstalk with H3 K4 and K79 methylation.

KMT2A DOT1L

1.63e-041067221726816
Pubmed

Crosstalk between NSL histone acetyltransferase and MLL/SET complexes: NSL complex functions in promoting histone H3K4 di-methylation activity by MLL/SET complexes.

KANSL1 KMT2A

1.63e-041067224244196
Pubmed

Genetic patterning of the posterior neuropore region of curly tail mouse embryos: deficiency of Wnt5a expression.

HOXB1 TBXT

1.63e-04106729712518
Pubmed

CBX8, a polycomb group protein, is essential for MLL-AF9-induced leukemogenesis.

KMT2A DOT1L

1.63e-041067222094252
Pubmed

Genetic patterning of the developing mouse tail at the time of posterior neuropore closure.

HOXB1 TBXT

1.63e-04106729415428
Pubmed

Porcupine homolog is required for canonical Wnt signaling and gastrulation in mouse embryos.

HOXB1 TBXT

1.63e-041067221554866
Pubmed

Segmental border is defined by Ripply2-mediated Tbx6 repression independent of Mesp2.

TBXT NOTCH1

1.63e-041067225641698
Pubmed

The retinoic acid-metabolizing enzyme, CYP26A1, is essential for normal hindbrain patterning, vertebral identity, and development of posterior structures.

HOXB1 TBXT

1.63e-041067211157778
Pubmed

Regionalisation of anterior neuroectoderm and its competence in responding to forebrain and midbrain inducing activities depend on mutual antagonism between OTX2 and GBX2.

HOXB1 DMBX1

1.63e-041067211731459
Pubmed

Large-scale screen for genes controlling mammalian embryogenesis, using high-throughput gene expression analysis in mouse embryos.

HOXA5 HOXB1 TBXT NOTCH1

2.17e-0415267411044609
Pubmed

Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.

TANC2 ABLIM1 TTC28 R3HDM2 SORBS1 NOTCH1

2.22e-0444667624255178
Pubmed

The bHLH regulator pMesogenin1 is required for maturation and segmentation of paraxial mesoderm.

TBXT NOTCH1

2.38e-041267211124811
Pubmed

Notch1 is required for the coordinate segmentation of somites.

TBXT NOTCH1

2.38e-04126727789282
Pubmed

Inhibition of RIF1 by SCAI Allows BRCA1-Mediated Repair.

REV3L DOT1L

2.38e-041267228700933
Pubmed

The transcription factor HNF3beta is required in visceral endoderm for normal primitive streak morphogenesis.

HOXB1 TBXT

2.38e-04126729671576
Pubmed

Requirement for tumor suppressor Apc in the morphogenesis of anterior and ventral mouse embryo.

HOXB1 TBXT

2.38e-041267212645927
Pubmed

Forebrain and midbrain regions are deleted in Otx2-/- mutants due to a defective anterior neuroectoderm specification during gastrulation.

HOXB1 TBXT

2.38e-04126727588062
Pubmed

Partial functional redundancy between Hoxa5 and Hoxb5 paralog genes during lung morphogenesis.

HOXA5 NOTCH1

2.38e-041267223585229
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

TANC2 GPBAR1 TCF12 TTC28 CECR2 CHAF1A C16orf96 REV3L TP73

2.81e-04111667931753913
Pubmed

Node and midline defects are associated with left-right development in Delta1 mutant embryos.

TBXT NOTCH1

2.81e-041367212441287
Pubmed

Long-range regulation by shared retinoic acid response elements modulates dynamic expression of posterior Hoxb genes in CNS development.

HOXA5 HOXB1

2.81e-041367224525295
Pubmed

TMEM132A regulates mouse hindgut morphogenesis and caudal development.

TMEM132A TBXT

2.81e-041367237390294
Pubmed

A targeted mouse Otx2 mutation leads to severe defects in gastrulation and formation of axial mesoderm and to deletion of rostral brain.

HOXB1 TBXT

2.81e-04136728565836
Pubmed

Hox-1.11 and Hox-4.9 homeobox genes.

HOXA5 HOXB1

3.28e-04146721348361
Pubmed

Altered neuronal lineages in the facial ganglia of Hoxa2 mutant mice.

HOXB1 NOTCH1

3.28e-041467218164701
Pubmed

Genetic rescue of segmentation defect in MesP2-deficient mice by MesP1 gene replacement.

TBXT NOTCH1

3.28e-04146729739106
Pubmed

O-linked N-acetylglucosamine proteomics of postsynaptic density preparations using lectin weak affinity chromatography and mass spectrometry.

SORBS1 CTNND2

3.28e-041467216452088
InteractionBICD1 interactions

RANBP2 TTC28 CENPE SORBS1 SYBU PAN3 VIRMA TAB3

1.22e-06250648int:BICD1
InteractionYWHAH interactions

TANC2 ZCCHC14 ABLIM1 HIVEP2 GRID2IP TTC28 ZC3H13 RECQL4 KMT2A R3HDM2 SORBS1 PAN3 FERMT2 VIRMA TAB3

1.35e-0611026415int:YWHAH
InteractionCREBBP interactions

HOXB1 HIVEP2 TCF12 CHAF1A SERTAD2 KMT2A TBXT VIRMA TFAP2B RXRG TP73

2.60e-065996411int:CREBBP
InteractionTLE3 interactions

HIVEP2 TCF12 CHERP CECR2 KMT2A TBXT DOT1L VIRMA NOTCH1

2.77e-06376649int:TLE3
InteractionYWHAG interactions

TANC2 ABLIM1 HIVEP2 GRID2IP TTC28 BCLAF1 ZC3H13 CHAF1A RECQL4 KMT2A R3HDM2 SORBS1 PAN3 VIRMA TAB3

6.24e-0612486415int:YWHAG
InteractionASF1A interactions

ZC3H13 CHAF1A RECQL4 KMT2A PAN3 DOT1L TP73

1.38e-05249647int:ASF1A
InteractionCKS1B interactions

TCF12 SERTAD2 FRS2 KMT2A IKZF5

1.49e-0598645int:CKS1B
InteractionCDKL5 interactions

RANBP2 SORBS1 CTNND2 VIRMA ELFN2

2.97e-05113645int:CDKL5
InteractionYWHAE interactions

TANC2 ABLIM1 HIVEP2 TTC28 CENPE CHAF1A RECQL4 KMT2A R3HDM2 SORBS1 DOT1L FERMT2 VIRMA TAB3

3.14e-0512566414int:YWHAE
InteractionRBBP5 interactions

KANSL1 ZC3H13 ZNF335 RECQL4 KMT2A TBXT VIRMA

3.43e-05287647int:RBBP5
InteractionWTAP interactions

TCF12 ZC3H13 RECQL4 CPNE1 DOT1L VIRMA

3.47e-05194646int:WTAP
InteractionDHX8 interactions

CHERP KANSL1 BCLAF1 ZC3H13 DOT1L VIRMA NOTCH1

3.82e-05292647int:DHX8
InteractionYWHAQ interactions

TANC2 ABLIM1 HIVEP2 TTC28 ZC3H13 CHAF1A RECQL4 KMT2A R3HDM2 SORBS1 PAN3 VIRMA TAB3

4.10e-0511186413int:YWHAQ
InteractionSMARCA5 interactions

RANBP2 CECR2 ZC3H13 CHAF1A RECQL4 DOT1L VIRMA NOTCH1

4.88e-05415648int:SMARCA5
InteractionAFF1 interactions

SPATA6 KMT2A DOT1L VIRMA

5.75e-0566644int:AFF1
InteractionYWHAB interactions

TANC2 ABLIM1 GRID2IP TTC28 CENPE CHAF1A RECQL4 KMT2A R3HDM2 SORBS1 DOT1L VIRMA

7.17e-0510146412int:YWHAB
InteractionNCOA6 interactions

ZNF335 KMT2A TBXT VIRMA RXRG

9.75e-05145645int:NCOA6
InteractionSMARCC2 interactions

CHAF1A RECQL4 KMT2A TBXT DOT1L VIRMA NOTCH1

1.26e-04353647int:SMARCC2
GeneFamilyZinc fingers RANBP2-type |RNA binding motif containing

RANBP2 TAB3

1.23e-032145289
GeneFamilyTetratricopeptide repeat domain containing|Bardet-Biedl syndrome associated|BBSome

TANC2 RANBP2 TTC28

2.93e-03115453769
GeneFamilyZinc fingers C2H2-type|Lysine methyltransferases|PR/SET domain family

KMT2A DOT1L

3.23e-0334452487
CoexpressionMIKKELSEN_NPC_HCP_WITH_H3K27ME3

CADM3 HOXB1 VGLL2 TBXT TFAP2B DMBX1 RXRG TP73

2.76e-06345678M2009
CoexpressionMIKKELSEN_NPC_HCP_WITH_H3K27ME3

CADM3 HOXB1 VGLL2 TBXT TFAP2B DMBX1 RXRG TP73

2.88e-06347678MM860
CoexpressionLAKE_ADULT_KIDNEY_C4_PROXIMAL_TUBULE_EPITHELIAL_CELLS_S2

ABLIM1 TCF12 KANSL1 TTC28 GLIS3 LRMDA

5.98e-06176676M39223
CoexpressionGSE16450_IMMATURE_VS_MATURE_NEURON_CELL_LINE_UP

TANC2 ZCCHC14 ABLIM1 KANSL1 NLRP1 PAN3

1.07e-05195676M7397
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2-D175|Adult / Lineage, Cell type, age group and donor

TANC2 TTC28 KCND3 ARHGEF38 GLIS3 TMC5

3.97e-07188676ec38def1fdbb34ed9b30244806975bd5a4370164
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TANC2 PSORS1C1 ARHGEF38 GLIS3 ELFN2 TFAP2B

4.92e-07195676938b31dbf1674ee6fd0123bc88391ddcaf151217
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TANC2 PSORS1C1 ARHGEF38 GLIS3 ELFN2 TFAP2B

4.92e-07195676d39e9e6544f49e677ebe528c6fe60b99a3630e30
ToppCellParenchymal-NucSeq|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations

TANC2 TCF12 KANSL1 TTC28 GLIS3 PAN3

5.37e-071986761996373bdccc55aac347d349bd22f6aad6d0c668
ToppCellCOVID-19-Heart-Neuronal|COVID-19 / Disease (COVID-19 only), tissue and cell type

CADM3 SORBS1 SYBU CTNND2 RXRG

5.48e-0616867588c2c574f428c2502b5fe099bd73b0758f668ef6
ToppCellfacs-Large_Intestine-Distal-18m-Epithelial-epithelial_cell_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HIVEP2 CENPE CHAF1A REV3L NOTCH1

6.32e-06173675a5172dee859bf6c2eed46c48bd64dfef0ff9f28f
ToppCellfacs-Large_Intestine-Distal-18m-Epithelial-Lgr5-_amplifying_undifferentiated_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HIVEP2 CENPE CHAF1A REV3L NOTCH1

6.32e-06173675639b5b0b33ce5aa0bc26363c059717012ddc14c0
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TANC2 HOXB1 ABLIM1 ARHGEF38 MUC16

7.45e-061796756e965e424eebef50f0202cff75f458be395cfca1
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ABLIM1 NYAP2 CECR2 ARHGEF38 TFAP2B

7.87e-0618167522363c5835dd6cef8f895ab9362e0837d92b15b1
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TANC2 ABLIM1 CECR2 ARHGEF38 TFAP2B

8.52e-06184675d33de57876817050b294f2ecb0a4eb0634cfa7f0
ToppCellpdx|World / Sample and Cell Type and Tumor Cluster (all cells)

KANSL1 TTC28 FRS2 R3HDM2 CTNND2

8.98e-06186675de8e538c8767d41b8a52f5e58ba1affd4e7244c4
ToppCellpdx-Tumor_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

KANSL1 TTC28 FRS2 R3HDM2 CTNND2

8.98e-061866750b88a87158a9ca8de3bf40a4ff1687150707a5f0
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TANC2 ABLIM1 ARHGEF38 GLIS3 TFAP2B

9.95e-06190675bf4511395fa97efd1c1cd17cc9bebb0271ee7f0e
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TANC2 ABLIM1 ARHGEF38 GLIS3 TFAP2B

9.95e-06190675b6b8964b4910083499681b5fdf554e127b6a4c4e
ToppCellPBMC-Severe-Myeloid-Neutrophil-Neutrophil-Neu_4|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

KANSL1 CENPE RECQL4 ATG2B CPNE1

9.95e-061906753f0c7d130f66faea778fe567604edf1b4cdf85b3
ToppCellLV-06._Ventricular_Cardiomyocyte_II|LV / Chamber and Cluster_Paper

GREB1L ABLIM1 KCND3 SORBS1 CTNND2

1.02e-0519167525f3eb34f4e70761e81e84c8a5829f216108cbc6
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TANC2 ABLIM1 ARHGEF38 GLIS3 TFAP2B

1.02e-051916752fa1b9e76a0ed2d2f0de74349e266cf4a5f51aad
ToppCellLA-03._Atrial_Cardiomyocyte|LA / Chamber and Cluster_Paper

GREB1L ABLIM1 KCND3 SORBS1 CTNND2

1.02e-051916755d1b674eb7703830b7ce8bbeac3363cabd0e6ae9
ToppCell10x5'-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8|lymph-node_spleen / Manually curated celltypes from each tissue

RANBP2 ABLIM1 KANSL1 KMT2A NLRP1

1.05e-0519267547646d7e4990be85072987f92bf18d52f8da752e
ToppCellrenal_cortex_nuclei|World / Celltypes from Cells and Nuclei per compartment and clinical group

TCF12 TTC28 GLIS3 PAN3 LRMDA

1.05e-05192675e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCellPBMC-Severe-Myeloid-Neutrophil-Neutrophil-Neu_4|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

KANSL1 CENPE RECQL4 ATG2B CPNE1

1.05e-05192675c09dcc73ff9c3855a0f3d7bfa0d5c99c09a117f2
ToppCell5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-myocytic|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GPBAR1 KCND3 SORBS1 REV3L FERMT2

1.07e-051936754aa976b596830b585e8d9c808d5072ed23d13a7c
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT2-AT2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

TANC2 CECR2 ARHGEF38 GLIS3 TMC5

1.07e-05193675fd4d3c0d7caf8a2fff5b3d901fc28d19a8163cdf
ToppCellnucseq|World / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

TANC2 TCF12 KANSL1 PAN3 LRMDA

1.07e-05193675779276e775cb2492e8dd36436295a536084a6415
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TANC2 ABLIM1 ARHGEF38 GLIS3 TFAP2B

1.07e-05193675263d185af6ed80e639f864e4966268e0862c61dc
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TANC2 ABLIM1 ARHGEF38 GLIS3 TFAP2B

1.07e-0519367580e058c224749b5fe0ba3e944b48317c2371cb63
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TANC2 ABLIM1 ARHGEF38 GLIS3 TFAP2B

1.07e-05193675b991fbbb4618401624f0b3045f0e81a606d3a763
ToppCell5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-myocytic-SMC_(PLPP2+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GPBAR1 KCND3 SORBS1 REV3L FERMT2

1.07e-051936755578f7cb3ec68c9a38cc5304b618b81283024d5e
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

TANC2 CECR2 ARHGEF38 GLIS3 TMC5

1.07e-05193675f3cc7cfdbc164a4ed42f87647111522b7d393bcb
ToppCellBronchial-NucSeq|Bronchial / Cell types per location group and 10X technology with lineage, and cell group designations

TANC2 TCF12 KANSL1 TTC28 PAN3

1.16e-05196675ab53c742866945545a92e2e61850d63c80d9a2a6
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-AC-like-AC-like-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CADM3 KCNN3 SORBS1 CTNND2 FERMT2

1.16e-0519667545d1c0a962c4221c17393ee5566961d1deebf442
ToppCell3'-GW_trimst-1-SmallIntestine-Mesenchymal-myocytic-SMC_(PLPP2+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GPBAR1 KCND3 SORBS1 REV3L FERMT2

1.19e-05197675ba6393671a980a1d439307601d18db70a1b1e1f3
ToppCell(09)_Interm._secr.>cil.-(2)_GFP_FOXI1|(09)_Interm._secr.>cil. / shred by cell type by condition

TANC2 BCLAF1 ZC3H13 GLIS3 REV3L

1.24e-05199675fc680f85ebd3bab4c72876a19a461b0afb5f51ce
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-1_mon-Proliferating-Cycling_Progenitors|1_mon / Sample Type, Dataset, Time_group, and Cell type.

KANSL1 TPP1 SERTAD2 KMT2A NOTCH1

1.24e-05199675358c4b3037f59378db8916a2fbe9ed4830cf1449
ToppCellMacroglial-Astrocytes|Macroglial / cells hierarchy compared to all cells using T-Statistic

ABLIM1 GLIS3 KCNN3 PAPLN SORBS1

1.27e-05200675941536b7c32f1e63c70535233b2ccce0cd7bf96e
ToppCellMacroglial-Astrocytes-SLC14A1---|Macroglial / cells hierarchy compared to all cells using T-Statistic

ABLIM1 GLIS3 KCNN3 PAPLN SORBS1

1.27e-05200675d6fcbf4f4bc1b89a9929d7b114c6b907b6979900
ToppCellMacroglial-Astrocytes-SLC14A1----L1-6|Macroglial / cells hierarchy compared to all cells using T-Statistic

ABLIM1 GLIS3 KCNN3 PAPLN SORBS1

1.27e-05200675f861509b54185d89931db64da1b9d81986cc7938
ToppCellTracheal-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Mucous|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ABLIM1 ARHGEF38 MUC16 CTNND2 TMC5

1.27e-05200675c450a15e21fa72d071ed6e3b9f22de557a0f3cea
ToppCellTracheal-NucSeq-Epithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ABLIM1 ARHGEF38 MUC16 LRP5 TMC5

1.27e-05200675d3af0a706baf66e3f32e67b17dcfc31e5b32ce0e
ToppCellMacroglial-Astrocytes-SLC14A1|Macroglial / cells hierarchy compared to all cells using T-Statistic

ABLIM1 GLIS3 KCNN3 PAPLN SORBS1

1.27e-0520067516f468217427921fa18c6d078ffa990eb019b257
ToppCellMacroglial-Astrocytes-GFAP---|Macroglial / cells hierarchy compared to all cells using T-Statistic

ABLIM1 GLIS3 KCNN3 PAPLN SORBS1

1.27e-0520067588d66550781a3c9102ff7455f5cff6fb072943cd
ToppCellMacroglial-Astrocytes-GFAP-|Macroglial / cells hierarchy compared to all cells using T-Statistic

ABLIM1 GLIS3 KCNN3 PAPLN SORBS1

1.27e-05200675d6a059b0ef763c281c60b1ac76da6079ea822f80
ToppCellMacroglial-Astrocytes-GFAP--|Macroglial / cells hierarchy compared to all cells using T-Statistic

ABLIM1 GLIS3 KCNN3 PAPLN SORBS1

1.27e-0520067516269fa4adb28fc6ed032bbdba8781237dd0d249
ToppCellMacroglial-Astrocytes-GFAP----L1-2|Macroglial / cells hierarchy compared to all cells using T-Statistic

ABLIM1 GLIS3 KCNN3 PAPLN SORBS1

1.27e-05200675c6f43bbbd5df5f2c19ae385f1a6b6a330abede2f
ToppCellMacroglial-Astrocytes-SLC14A1--|Macroglial / cells hierarchy compared to all cells using T-Statistic

ABLIM1 GLIS3 KCNN3 PAPLN SORBS1

1.27e-052006750442894c39eec69850c090957a5dc7bcecd21e04
ToppCellMacroglial-Astrocytes-GFAP|Macroglial / cells hierarchy compared to all cells using T-Statistic

ABLIM1 GLIS3 KCNN3 PAPLN SORBS1

1.27e-0520067579634b1086934412ae92f259ab43554ce545008f
ToppCellMacroglial-Astrocytes-SLC14A1-|Macroglial / cells hierarchy compared to all cells using T-Statistic

ABLIM1 GLIS3 KCNN3 PAPLN SORBS1

1.27e-0520067501819446deeab9054f5cfe889d53bb49d137dbc0
ToppCellTracheal-NucSeq-Epithelial-Epi_submucosal-gland|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ABLIM1 ARHGEF38 MUC16 LRP5 TMC5

1.27e-052006750eb9ad8c0373bcc62029ec21c590ed03aaacd039
ToppCellEntopeduncular-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn_(Dcn)-|Entopeduncular / BrainAtlas - Mouse McCarroll V32

PCDHGB1 GLIS3 PAPLN TFAP2B

3.92e-05126674f1f24b06d301c266226d1a59dd28585f5ac68f29
ToppCellEntopeduncular-Endothelial-ENDOTHELIAL_TIP-Dcn_1|Entopeduncular / BrainAtlas - Mouse McCarroll V32

PCDHGB1 GLIS3 PAPLN TFAP2B

3.92e-05126674fe6900eb37e4f09465a1276586c73dd38545fa2a
ToppCellEntopeduncular-Endothelial-ENDOTHELIAL_TIP|Entopeduncular / BrainAtlas - Mouse McCarroll V32

PCDHGB1 GLIS3 PAPLN TFAP2B

3.92e-051266743d507f829882d043f633db2612b76936e2042445
ToppCellEntopeduncular-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1|Entopeduncular / BrainAtlas - Mouse McCarroll V32

PCDHGB1 GLIS3 PAPLN TFAP2B

3.92e-051266741ac4cc747e466bc79e33b97608b19ad29a7a6a41
ToppCellEntopeduncular-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn_(Dcn)|Entopeduncular / BrainAtlas - Mouse McCarroll V32

PCDHGB1 GLIS3 PAPLN TFAP2B

3.92e-051266742de551d7a8765afec1da8852727c79fec90f45f8
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_low-phase|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CENPE C16orf96 RXRG TP73

4.99e-05134674e0f3ca643c206929203d80095663a5eac98ac088
ToppCellFetal_29-31_weeks-Epithelial-club_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

GREB1L ARHGEF38 SYBU TMC5

1.04e-041626745c9bc3c3857a99d8a3caf359a7eb279ce9cc1c81
ToppCellmild_COVID-19_(asymptomatic)-pDC|World / disease group, cell group and cell class (v2)

KCND3 CHAF1A LRP5 SORBS1

1.17e-04167674bf08f17965a4dd03f371b4ed0ab0d5e62ed61307
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Hematologic-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HOXA5 HOXB1 KANSL1 CECR2

1.22e-041696744e1322cc5e1733e9fb19e08f739a30206f43cea8
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ABLIM1 PSORS1C1 ARHGEF38 GLIS3

1.31e-041726740c2d0bb767e5ce089b42ad49e8b303a103de2d5c
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1_FGFR3_MT1G|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GLIS3 KCNN3 PAPLN NOTCH1

1.31e-0417267455fba5ce0ead1114e1a76f67ad68432c6bac90e5
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ABLIM1 PSORS1C1 ARHGEF38 GLIS3

1.31e-04172674eeed177a03c116e9815a8e086d24efc9643b16a4
ToppCellCOVID-19-Heart-Neuronal|Heart / Disease (COVID-19 only), tissue and cell type

CADM3 SYBU CTNND2 RXRG

1.34e-041736746fb5f9e6536a5d57fd8e6657b494047a2d0bc9c7
ToppCelldroplet-Liver-LIVER-NPC-1m-Endothelial-Hepatocyte_(Pericentral)|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HOXA5 SPATA6 SYBU NOTCH1

1.40e-0417567498dc3b6f69a29d587f503898f09912700950e3d9
ToppCellfacs-Lung-Endomucin_-18m-Endothelial-Lymphatic_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCF12 CENPE KCNN3 PLA2G2C

1.40e-041756740801cccec6915aefc135262fc74580280fd51aa5
ToppCellfacs-Lung-Endomucin_-18m-Endothelial-endothelial_cell_of_lymphatic_vessel|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCF12 CENPE KCNN3 PLA2G2C

1.40e-0417567409163e7030f76d706eccabdb1d5ec45f8412aa75
ToppCell10x_3'_v2v3-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia/MHC-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

KCNN3 SORBS1 SYBU CTNND2

1.40e-04175674e99e145a152f534b75267ec492a252a0b814b4f8
ToppCelldroplet-Lung-21m-Hematologic-myeloid-myeloid_dendritic_cell-proliferating_dendritic|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CADM3 CENPE CHAF1A CTNND2

1.40e-0417567473f25bd54309aed1480ddc44bdab518b17e71f92
ToppCellFrontal_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)-Synpr-Inhibitory_Neuron.Gad1Gad2-Slc17a8.Synpr-Sncg-Yjefn3_(Neuron.Gad1Gad2-Slc17a8.Synpr-Sncg-Yjefn3)-|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

GRID2IP VGLL2 DMBX1

1.41e-0467673e53dfc288c943656a0b064afe593ea2101d75437
ToppCellFrontal_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)-Synpr-Inhibitory_Neuron.Gad1Gad2-Slc17a8.Synpr-Sncg-Yjefn3_(Neuron.Gad1Gad2-Slc17a8.Synpr-Sncg-Yjefn3)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

GRID2IP VGLL2 DMBX1

1.41e-04676731841cee311a4b1b802c9e872793435afb730592f
ToppCellAdult-Epithelial-club_cell-D175|Adult / Lineage, Cell type, age group and donor

ARHGEF38 GLIS3 LRP5 TMC5

1.46e-04177674d652b7d84fe6aa38319d8d5adc72c70441bd0088
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

ABLIM1 NYAP2 CTNND2 TMC5

1.53e-041796744f6ca313b78aa93557937a046c44dcf8bcc9963c
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CHAF1A RECQL4 DOT1L TP73

1.53e-0417967488d44b04eb5c079531db663ed98ddb20b60feb9a
ToppCellControl-Epithelial_cells-AT2|Control / group, cell type (main and fine annotations)

TANC2 CECR2 ARHGEF38 GLIS3

1.56e-04180674198b19e7910b4a8cc7e820c525ab357c7f99f578
ToppCellcritical-Lymphoid-NK|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

CADM3 SORBS1 FERMT2 TFAP2B

1.56e-041806745abf778395392244daaec876f306ed7e4f388686
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TANC2 CECR2 ARHGEF38 TFAP2B

1.63e-04182674a8cc56f32efe180e8fb5d69dbe606a794b3db700
ToppCellChildren_(3_yrs)-Epithelial-lung_goblet_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

GLIS3 MUC16 SYBU TMC5

1.63e-041826743f1a666fe27dd7529c114539ed5f6b8ca585c875
ToppCellCOVID-19-lung-AT1|lung / Disease (COVID-19 only), tissue and cell type

ABLIM1 NYAP2 CTNND2 TMC5

1.66e-04183674942530449e9c6583705eeb8f6f12621daea57252
ToppCell5'-Adult-LargeIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KCND3 SORBS1 CTNND2 FERMT2

1.66e-0418367461a73de857f4ae02dcba3af348f436f602b28ff2
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ABLIM1 CECR2 ARHGEF38 TFAP2B

1.70e-041846748fd8bd3d28d0ee6f0ef1f14e354d8eaf63a8081b
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ABLIM1 CECR2 ARHGEF38 TFAP2B

1.70e-04184674e8238fe58f94b4f5700ab7f343fb06ea61e899a9
ToppCellLV-15._Ventricular_Cardiomyocyte_III|LV / Chamber and Cluster_Paper

GREB1L ABLIM1 SORBS1 CTNND2

1.70e-04184674ab7a1620c14a9d9b6be1b47c559931e345e9eef8
ToppCellwk_20-22-Epithelial-PNS-intermediate_Schwann|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

CADM3 TMEM132A SORBS1 TAB3

1.70e-041846744e3ba64692868563a579902aa9c6f88cab5bce26
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1|Children_(3_yrs) / Lineage, Cell type, age group and donor

ABLIM1 NYAP2 CTNND2 TMC5

1.73e-041856741c222f7285d6e3dae0354dc7e853ddc0ea55e63e
ToppCellCOVID-19-Heart-CM_2|COVID-19 / Disease (COVID-19 only), tissue and cell type

GREB1L ABLIM1 SORBS1 CTNND2

1.73e-04185674549eeb521c3985bff396ea0f202db21822efa51f
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1-D175|Adult / Lineage, Cell type, age group and donor

ABLIM1 CTNND2 TMC5 FERMT2

1.73e-0418567432b4e68e551d435a732f253f6ad83408c759a642
ToppCellLV-15._Ventricular_Cardiomyocyte_III|World / Chamber and Cluster_Paper

GREB1L ABLIM1 SORBS1 CTNND2

1.73e-041856746baccb26f999145e51b91d94315bf8d4655bef31
ToppCell(5)_Epithelial_cells-(5)_Glands_duct|(5)_Epithelial_cells / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)

ARHGEF38 GLIS3 MUC16 TMC5

1.77e-04186674219b1aeca17503244fabbb780bca58f22c7c0f27
ToppCell(5)_Glands_duct|World / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)

ARHGEF38 GLIS3 MUC16 TMC5

1.77e-04186674ad8d5010e5095508f4995e0c6c016a44e8ffb8dd
ToppCellEpithelial-alveolar_epithelial_cell_type_1|World / Lineage, Cell type, age group and donor

ABLIM1 NYAP2 CTNND2 TMC5

1.77e-0418667409d95daa3387a4814cffaa4b798cc2810c3759d0
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Astro-Astrocyte|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CECR2 GLIS3 PAPLN NOTCH1

1.81e-04187674dd1d91f101b837bba513f77defa6e6902b2c0570
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TANC2 ARHGEF38 SYBU TFAP2B

1.81e-0418767487b3d0478693d4c54ff06b74e5903036b9c1ee6a
ToppCellCOVID-19-Fibroblasts-Airway_smooth_muscle|COVID-19 / group, cell type (main and fine annotations)

TTC28 GLIS3 SORBS1 FERMT2

1.81e-04187674464a0c3b92b778911b5f9cd73642e09e3472063a
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Astro|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CECR2 GLIS3 PAPLN NOTCH1

1.81e-04187674ae90c263f80c36a410150d499e268d198944a3d9
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TANC2 ARHGEF38 SYBU TFAP2B

1.81e-0418767442a1267bfc27b4460b8409ada580a87c4385841c
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TANC2 ARHGEF38 SYBU TFAP2B

1.81e-0418767464afdea159f5e67a1e5cea35ce898aae6e80aea5
ToppCellhuman_hepatoblastoma-Tumor_cells-T2|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

ZC3H13 R3HDM2 CTNND2 LRMDA

1.81e-04187674f3e37c18ac6471c7992609bbddfa4975571c815c
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

HOXB1 MUC16 LRP5 TMC5

1.81e-0418767471d99a1a95d3692a2891da49d4a243bae6e07fd0
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CENPE CHAF1A RECQL4 TP73

1.81e-041876749351fa87b69a951af85b10bf91fe9b1cce8c0517
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-myocytic-SMC_(PLPP2+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GPBAR1 KCND3 SORBS1 FERMT2

1.81e-041876743912bbb610a4a84791e9bda92a2d57a52c31d29e
ToppCellLA-03._Atrial_Cardiomyocyte|World / Chamber and Cluster_Paper

GREB1L KCND3 SORBS1 CTNND2

1.84e-041886746d249fe92d51a19da19ec14bb2262d394255d577
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

RANBP2 KANSL1 BCLAF1 KMT2A

1.84e-04188674ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
Diseasehematocrit

NYAP2 HIVEP2 CHAF1A PSORS1C1 SERTAD2 GLIS3 R3HDM2 SORBS1 DOT1L TMC5 LRMDA TFAP2B

2.59e-0610116712EFO_0004348
Diseasefree androgen index

NYAP2 TCF12 SERTAD2 GLIS3 LRP5 R3HDM2 RNF212B

2.25e-05374677EFO_0007005
Diseaseasthma

CADM3 SPEM2 HIVEP2 VGLL2 PSORS1C1 GLIS3 MUC16 TBXT CTNND2

4.89e-05751679MONDO_0004979
Diseaseinsomnia measurement

TANC2 HOXB1 TCF12 GLIS3 KMT2A CTNND2 LRMDA

6.56e-05443677EFO_0007876
DiseaseQRS-T angle

KANSL1 VGLL2 KMT2A LRMDA

1.01e-04106674EFO_0020097
DiseaseAngle Closure Glaucoma

GLIS3 FERMT2

1.06e-047672C0017605
DiseaseBMI-adjusted waist-hip ratio, sex interaction measurement

NYAP2 CECR2 FERMT2

1.29e-0443673EFO_0007788, EFO_0008343
Diseasetestosterone measurement

NYAP2 TCF12 TTC28 CENPE CECR2 SERTAD2 GLIS3 LRP5 C16orf96 R3HDM2 RNF212B

1.30e-0412756711EFO_0004908
Diseasechronic obstructive pulmonary disease

HIVEP2 KANSL1 SERTAD2 ARHGEF38 FRS2 GLIS3 DOT1L LRMDA

1.63e-04688678EFO_0000341
DiseaseSmall cell carcinoma of lung

BCLAF1 KMT2A TP73

2.55e-0454673C0149925
Diseaseprimary angle closure glaucoma

GLIS3 FERMT2

2.76e-0411672EFO_1001506
Diseaseforced expiratory volume

HOXA5 KANSL1 ARHGEF38 FRS2 GLIS3 LRP5 CTNND2 LRMDA

4.09e-04789678EFO_0004314
DiseaseCraniofacial Abnormalities

HOXB1 KANSL1 TFAP2B NOTCH1

4.45e-04156674C0376634
Diseaseearly cardiac repolarization measurement

KCND3 LRP5

4.54e-0414672EFO_0004885
Diseasehepcidin:transferrin saturation ratio

MUC16 PAN3

5.23e-0415672EFO_0007902
DiseaseAutosomal recessive primary microcephaly

CENPE ZNF335

5.23e-0415672cv:C3711387
Diseasevisceral:subcutaneous adipose tissue ratio

NYAP2 TBXT TP73

5.49e-0470673EFO_0004767
Diseasechildhood trauma measurement, alcohol consumption measurement

TANC2 PCDHGB1 NLRP1

5.73e-0471673EFO_0007878, EFO_0007979
DiseaseQRS duration

NYAP2 TCF12 KCND3 KMT2A LRMDA

5.88e-04298675EFO_0005055
Diseaseleptin measurement, type 2 diabetes mellitus

NYAP2 GLIS3

5.97e-0416672EFO_0005000, MONDO_0005148
DiseaseMyeloid Leukemia

ATG2B KMT2A

7.59e-0418672C0023470
DiseaseLeukemia, Monocytic, Chronic

ATG2B KMT2A

7.59e-0418672C0023466
Diseaseovarian carcinoma

NYAP2 SPATA6 TTC28 PSORS1C1 NLRP1

8.22e-04321675EFO_0001075
DiseaseSplenomegaly

KCNN3 NOTCH1

1.14e-0322672C0038002
Diseasealbuminuria

NYAP2 PAPLN LRMDA

1.29e-0394673EFO_0004285
Diseaseunipolar depression, schizophrenia

ZCCHC14 PSORS1C1

1.47e-0325672EFO_0003761, MONDO_0005090
Diseaseatrial fibrillation

KCND3 VGLL2 KCNN3 LRMDA RXRG

1.56e-03371675EFO_0000275
Diseaseleprosy

KANSL1 PSORS1C1 ELFN2

1.68e-03103673EFO_0001054
Diseaseneuroticism measurement, cognitive function measurement

ZCCHC14 GLIS3 CPNE1 R3HDM2 SYBU CTNND2

1.80e-03566676EFO_0007660, EFO_0008354
DiseaseIniencephaly

CECR2 TBXT

1.85e-0328672C0152234
DiseaseTethered Cord Syndrome

CECR2 TBXT

1.85e-0328672C0080218
DiseaseSpinal Cord Myelodysplasia

CECR2 TBXT

1.85e-0328672C0344479
DiseaseExencephaly

CECR2 TBXT

1.85e-0328672C0266453
DiseaseNeurenteric Cyst

CECR2 TBXT

1.85e-0328672C0027806
DiseaseAcrania

CECR2 TBXT

1.85e-0328672C0702169
DiseaseDiastematomyelia

CECR2 TBXT

1.85e-0328672C0011999
DiseaseCraniorachischisis

CECR2 TBXT

1.98e-0329672C0152426
Diseasetriglyceride measurement, intermediate density lipoprotein measurement

NYAP2 CPNE1 R3HDM2

2.08e-03111673EFO_0004530, EFO_0008595
DiseaseNeural Tube Defects

CECR2 TBXT

2.12e-0330672C0027794
Diseasecardiac arrhythmia

KCND3 LRMDA

2.12e-0330672EFO_0004269
Diseasecervical cancer (is_implicated_in)

KMT2A TP73

2.12e-0330672DOID:4362 (is_implicated_in)

Protein segments in the cluster

PeptideGeneStartEntry
YTPTTSRSPQHFHRP

ABLIM1

466

O14639
NSTPPSHPDYRALDD

ARHGEF38

256

Q9NXL2
ASSPQDAYRSPHSPF

DOT1L

446

Q8TEK3
VNDPSPVPSSSSTYH

CADM3

316

Q8N126
PSTTYLHTPTPSEDA

CHAF1A

776

Q13111
PQRPASHFQPRAYSS

CECR2

1371

Q9BXF3
PPAHTGTYRTSTAPS

CTNND2

446

Q9UQB3
TSPAKSYISPHSSPS

ATG2B

1571

Q96BY7
SYISPHSSPSHTPTR

ATG2B

1576

Q96BY7
YSSAPPLSHTPSSDF

TFAP2B

51

Q92481
PRDSYNETPSPASTH

RNF212B

206

A8MTL3
NETPSPASTHSLSYR

RNF212B

211

A8MTL3
LPTSNYSTSSHAPPT

R3HDM2

486

Q9Y2K5
KHSTPSPTRYSLSPS

RANBP2

776

P49792
DDTDRHSPSSPSPYE

PLA2G2C

56

Q5R387
SPLYSTPSESSHSSP

MUC16

8866

Q8WXI7
PNYSHSEPDTTPSIA

MUC16

11366

Q8WXI7
QNYPSTRSPSLSSHP

KCND3

526

Q9UK17
FLTPPSQHSYSSPVD

NOTCH1

2481

P46531
ASSPERHYTPLPSAS

LRMDA

151

Q9H2I8
ASRDSPGPSIAYHPS

GPBAR1

306

Q8TDU6
HYTLDPSSRNCSPPT

LRP5

931

O75197
LHSSPTAFRAPPSSN

KCNN3

101

Q9UGI6
YDPSLSSHQAPPNTD

PCDHGB1

796

Q9Y5G3
LYQALPSSPDHESPS

NLRP1

156

Q9C000
PAEPRYSQPATSTHS

HOXA5

81

P20719
SHDRLSYPPHSVSPT

TCF12

271

Q99081
STSSSPYVAASHTPP

TCF12

301

Q99081
IYSPDHTSSSFPSNP

TCF12

346

Q99081
SEYSHGQSPRSPISP

KANSL1

981

Q7Z3B3
PYDAVHSGSLSRSSP

NYAP2

456

Q9P242
TPAHTGNYSLSPRPS

GREB1L

296

Q9C091
TSPEPRPSHSQRNYS

IKZF5

311

Q9H5V7
KPYSAHDPLTSPASS

PAN3

201

Q58A45
SSRAASASPYTPEHA

TP73

76

O15350
SASPYTPEHAASVPT

TP73

81

O15350
AYSAHSAPTSFPPSS

HOXB1

21

P14653
ESHPYASLDSSRAPS

GRID2IP

626

A4D2P6
EAFYSPPSHDRPRNS

CHERP

691

Q8IWX8
APSPPSQSLYDRVHS

C16orf96

1046

A6NNT2
GPSHSYSSSPLSLFR

DMBX1

251

Q8NFW5
PRYPSFGDASSHPSS

FRS2

151

Q8WU20
LSAYDNSPRSPHSPS

BCLAF1

216

Q9NYF8
TESSHSPYPSPRHSS

GLIS3

121

Q8NEA6
SPYPSPRHSSTRSHS

GLIS3

126

Q8NEA6
SPDRPPHSQTSGSCY

KMT2A

2121

Q03164
PTYDAHDGSPLSPTS

FERMT2

191

Q96AC1
SLPSPHPVRYFDNSS

CENPE

2651

Q02224
NGDPSSPDSLHYLSP

CPNE1

296

Q99829
HSPPSAQASALCYSP

PCDH11Y

1226

Q9BZA8
SSSDPLPATSYHSRD

nan

286

A6NNC1
PLFSSSDPLPATSSH

nan

826

A6NNC1
HYPPANSSLSSRSET

TMEM132A

66

Q24JP5
PSPRNQHSLYTATTP

TAB3

391

Q8N5C8
QHSLYTATTPPSSSP

TAB3

396

Q8N5C8
CSSPSNPRYHGLSPS

RECQL4

311

O94761
SPPHRDSAYISSSPL

TANC2

1446

Q9HCD6
EHFSRALSQPSSYSP

VGLL2

101

Q8N8G2
SHAILSPPSPSYNAE

REV3L

1081

O60673
HRSPHPSTEPLGYSS

SPEM2

361

Q0P670
GSPAPPFHSSSYRIS

PAPLN

896

O95428
REAPPAFSHLASPSS

SERTAD2

101

Q14140
VNIHPSYAPSSPSSS

SYBU

216

Q9NX95
YNTDHLALSPRASPS

SORBS1

1016

Q9BX66
PSPHKTYSLAPTSQA

SORBS1

1056

Q9BX66
LYSSPPSHSPFGLSS

PSORS1C1

136

Q9UIG5
SHPSYTDTPVSAPRT

RXRG

41

P48443
TLRSHRSSPYPSPYA

TBXT

281

O15178
HNASPPTSSSQYPSL

TBXT

336

O15178
HAPYSSSGTPDPVLS

ZCCHC14

851

Q8WYQ9
PSSPYSAHISKSPRN

TTC28

2291

Q96AY4
YSAASRTSPDHPTSL

TMC5

91

Q6UXY8
PRDFSPSSHHSSPGY

HIVEP2

2036

P31629
PNSYLPDSSSVSHGP

ZNF335

81

Q9H4Z2
SSLPDNRAYGETSPH

VIRMA

51

Q69YN4
YEQPTISSKSHSPSP

SPATA6

206

Q9NWH7
ASPYPSHSLSSPQRK

ZC3H13

371

Q5T200
SHPTPYSTDAQREPD

ELFN2

256

Q5R3F8
SSSPHLPPSSYFNAS

TPP1

431

O14773