Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncytoskeletal protein binding

CLIP4 FMR1 GAS2L3 SNX6 MARK3 CLMN TLN1 ARFGEF2 BBS4 FAM83D TLN2 ADD1 MAP3K1

1.35e-0410997213GO:0008092
GeneOntologyBiologicalProcesscell division

CDCA2 INTU FBXO5 CCNB3 ANAPC1 PKP4 BBS4 FAM83D NKX3-1 MYB CEP63

2.81e-056977211GO:0051301
Domain-

TLN1 TLN2

1.47e-0527221.20.1420.10
DomainTalin_middle

TLN1 TLN2

1.47e-052722PF09141
DomainVBS

TLN1 TLN2

1.47e-052722PF08913
DomainVinculin-bd_dom

TLN1 TLN2

1.47e-052722IPR015009
DomainTalin_cent

TLN1 TLN2

1.47e-052722IPR015224
DomainTalin-1

TLN1 TLN2

4.39e-053722IPR015710
DomainI_LWEQ

TLN1 TLN2

8.75e-054722PF01608
DomainILWEQ_dom

TLN1 TLN2

8.75e-054722IPR002558
DomainI_LWEQ

TLN1 TLN2

8.75e-054722PS50945
DomainILWEQ

TLN1 TLN2

8.75e-054722SM00307
DomainFERM_f0

TLN1 TLN2

8.75e-054722IPR032425
DomainFERM_f0

TLN1 TLN2

8.75e-054722PF16511
DomainILWEQ

TLN1 TLN2

8.75e-054722PD011820
Domain-

TLN1 TLN2

8.75e-0547221.20.1410.10
DomainVinculin/catenin

TLN1 TLN2

3.04e-047722IPR006077
DomainDUF1220

NBPF4 NBPF6

5.18e-049722SM01148
DomainNBPF_dom

NBPF4 NBPF6

7.88e-0411722IPR010630
DomainNBPF

NBPF4 NBPF6

7.88e-0411722PS51316
DomainDUF1220

NBPF4 NBPF6

7.88e-0411722PF06758
DomainIRS_PTB

TLN1 TLN2

1.29e-0314722IPR002404
DomainIRS

TLN1 TLN2

1.29e-0314722PF02174
DomainARM-type_fold

PKP4 CTNNBL1 ARFGEF2 HUWE1 TEX10 MAP3K1

1.95e-03339726IPR016024
DomainKRAB

ZSCAN20 ZNF540 ZFP28 ZNF350 ZNF699 ZNF160

2.98e-03369726SM00349
DomainKRAB

ZSCAN20 ZNF540 ZFP28 ZNF350 ZNF699 ZNF160

3.02e-03370726IPR001909
DomainUIM

STAM2 HUWE1

3.83e-0324722PS50330
DomainFERM_CS

TLN1 TLN2

3.83e-0324722IPR019747
DomainARM-like

PKP4 CTNNBL1 ARFGEF2 HUWE1 TEX10

3.87e-03270725IPR011989
DomainUIM_dom

STAM2 HUWE1

4.15e-0325722IPR003903
Domain-

ZNF502 ZSCAN20 ZNF644 ZNF540 ZFP28 ZNF350 ZNF699 ZNF160

4.52e-036797283.30.160.60
DomainHECT

HUWE1 HERC1

4.83e-0327722PF00632
DomainHECTc

HUWE1 HERC1

4.83e-0327722SM00119
DomainHECT_dom

HUWE1 HERC1

4.83e-0327722IPR000569
DomainHECT

HUWE1 HERC1

4.83e-0327722PS50237
Domainzf-C2H2

ZNF502 ZSCAN20 ZNF644 ZNF540 ZFP28 ZNF350 ZNF699 ZNF160

5.10e-03693728PF00096
DomainZnf_C2H2/integrase_DNA-bd

ZNF502 ZSCAN20 ZNF644 ZNF540 ZFP28 ZNF350 ZNF699 ZNF160

5.14e-03694728IPR013087
DomainUBA

MARK3 HUWE1

5.95e-0330722SM00165
DomainVWF_A

ANAPC1 SEC23B ITIH4

6.61e-0399723IPR002035
DomainFERM_N

TLN1 TLN2

7.16e-0333722PF09379
DomainFERM_N

TLN1 TLN2

7.16e-0333722IPR018979
Domainzf-C2H2_6

ZNF502 ZNF540 ZFP28 ZNF699 ZNF160

7.27e-03314725PF13912
DomainUBA

MARK3 HUWE1

8.48e-0336722PF00627
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

CDCA2 TET2 STAM2 ESYT2 RESF1 MARK3 CLMN PHF3 ANKRD26 DENND4C SEC23B

3.92e-06861791136931259
Pubmed

Both Talin-1 and Talin-2 correlate with malignancy potential of the human hepatocellular carcinoma MHCC-97 L cell.

TLN1 TLN2

5.09e-06279226822056
Pubmed

Extracellular rigidity sensing by talin isoform-specific mechanical linkages.

TLN1 TLN2

5.09e-06279226523364
Pubmed

[Association of the polymorphisms of sodium transport related genes with essential hypertension].

ATP1A2 ADD1

5.09e-06279219199261
Pubmed

An α2-Na/K ATPase/α-adducin complex in astrocytes triggers non-cell autonomous neurodegeneration.

ATP1A2 ADD1

5.09e-06279225344630
Pubmed

FMRP regulates actin filament organization via the armadillo protein p0071.

FMR1 PKP4

5.09e-06279224062571
Pubmed

New isoform-specific monoclonal antibodies reveal different sub-cellular localisations for talin1 and talin2.

TLN1 TLN2

5.09e-06279222306379
Pubmed

HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.

FMR1 FAM111A GAS2L3 MARK3 PHF3 CWC15 TLN1 CTNNBL1 OTUD4 TEX10 ADD1 MAP3K1 DUSP11

1.23e-051371791336244648
Pubmed

A novel gene family NBPF: intricate structure generated by gene duplications during primate evolution.

NBPF4 NBPF6 NBPF5P

1.46e-052179316079250
Pubmed

Type I gamma phosphatidylinositol phosphate kinase targets and regulates focal adhesions.

TLN1 TLN2

1.53e-05379212422220
Pubmed

Mechanotransduction in talin through the interaction of the R8 domain with DLC1.

TLN1 TLN2

1.53e-05379230028837
Pubmed

Vinculin and talin: focus on the myocardium.

TLN1 TLN2

1.53e-05379219952892
Pubmed

Talin depletion reveals independence of initial cell spreading from integrin activation and traction.

TLN1 TLN2

1.53e-05379219160486
Pubmed

Talin and vinculin are downregulated in atherosclerotic plaque; Tampere Vascular Study.

TLN1 TLN2

1.53e-05379227816808
Pubmed

CTNNBL1 facilitates the association of CWC15 with CDC5L and is required to maintain the abundance of the Prp19 spliceosomal complex.

CWC15 CTNNBL1

1.53e-05379226130721
Pubmed

Cytoskeletal proteins talin and vinculin in integrin-mediated adhesion.

TLN1 TLN2

1.53e-05379215494027
Pubmed

Glucose deprivation inhibits multiple key gene expression events and effector functions in CD8+ T cells.

TLN1 TLN2

1.53e-05379218792400
Pubmed

Vinculin controls talin engagement with the actomyosin machinery.

TLN1 TLN2

1.53e-05379226634421
Pubmed

Arginylation-dependent regulation of a proteolytic product of talin is essential for cell-cell adhesion.

TLN1 TLN2

1.53e-05379222665520
Pubmed

An essential role for talin during alpha(M)beta(2)-mediated phagocytosis.

TLN1 TLN2

1.53e-05379217202407
Pubmed

Loss of mouse cardiomyocyte talin-1 and talin-2 leads to β-1 integrin reduction, costameric instability, and dilated cardiomyopathy.

TLN1 TLN2

1.53e-05379228698364
Pubmed

A systems-wide screen identifies substrates of the SCFβTrCP ubiquitin ligase.

SMG7 ZNF644 DYNC2I1 HUWE1 DENND4C DUSP11

1.53e-0523279625515538
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

CDCA2 STAM2 ESYT2 SMG7 SNX6 PKP4 OTUD4 HUWE1 HERC1 TEX10 MTMR10

2.48e-051049791127880917
Pubmed

Rap1 binding to the talin 1 F0 domain makes a minimal contribution to murine platelet GPIIb-IIIa activation.

TLN1 TLN2

3.05e-05479230242097
Pubmed

Structural diversity in integrin/talin interactions.

TLN1 TLN2

3.05e-05479221134644
Pubmed

Vinculin regulates assembly of talin: β3 integrin complexes.

TLN1 TLN2

3.05e-05479224446374
Pubmed

Endothelial cell talin1 is essential for embryonic angiogenesis.

TLN1 TLN2

3.05e-05479221081121
Pubmed

Intrasteric inhibition mediates the interaction of the I/LWEQ module proteins Talin1, Talin2, Hip1, and Hip12 with actin.

TLN1 TLN2

3.05e-05479215581353
Pubmed

A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.

FMR1 SMG7 ANAPC1 PHF3 TLN1 ANKRD26 OTUD4 FAM83D ADD1

3.92e-0572479936232890
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

FBXO5 ANAPC1 CLMN PHF3 CWC15 DYNC2I1 HUWE1 DENND4C ADD1

4.32e-0573379934672954
Pubmed

Regulation of the action of early mitotic inhibitor 1 on the anaphase-promoting complex/cyclosome by cyclin-dependent kinases.

FBXO5 ANAPC1

5.07e-05579221454540
Pubmed

Clustering of alpha(5)beta(1) integrins determines adhesion strength whereas alpha(v)beta(3) and talin enable mechanotransduction.

TLN1 TLN2

5.07e-05579219805288
Pubmed

Talin1 regulates integrin turnover to promote embryonic epithelial morphogenesis.

TLN1 TLN2

5.07e-05579221670148
Pubmed

Quantification of integrin receptor agonism by fluorescence lifetime imaging.

TLN1 TLN2

5.07e-05579218216331
Pubmed

Kindlin-2 cooperates with talin to activate integrins and induces cell spreading by directly binding paxillin.

TLN1 TLN2

5.07e-05579226821125
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

ESYT2 ANAPC1 PHF3 ZNF644 ARFGEF2 OTUD4 TLN2 HUWE1 ADD1

6.55e-0577479915302935
Pubmed

Hypertonicity-responsive ubiquitin ligase RNF183 promotes Na, K-ATPase lysosomal degradation through ubiquitination of its β1 subunit.

STAM2 FBXO5 SNX6 TLN1 HUWE1 SEC23B ADD1

7.43e-0544979731732153
Pubmed

MEKK1-Dependent Activation of the CRL4 Complex Is Important for DNA Damage-Induced Degradation of p21 and DDB2 and Cell Survival.

IL17RB MAP3K1

7.60e-05679234251884
Pubmed

Mice carrying a complete deletion of the talin2 coding sequence are viable and fertile.

TLN1 TLN2

7.60e-05679222925892
Pubmed

Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

TET2 RESF1 HUWE1 ZNF160

8.52e-0510179410997877
Pubmed

Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

KIAA1210 ESYT2 INTU ZNF644

9.19e-0510379410574462
Pubmed

Talin regulates integrin β1-dependent and -independent cell functions in ureteric bud development.

TLN1 TLN2

1.06e-04779228993400
Pubmed

The primary cilium as the cell's antenna: signaling at a sensory organelle.

INTU BBS4

1.06e-04779216888132
Pubmed

Molecular architecture of the human Prp19/CDC5L complex.

CWC15 CTNNBL1

1.06e-04779220176811
Pubmed

Splicing and beyond: the many faces of the Prp19 complex.

CWC15 CTNNBL1

1.06e-04779223742842
Pubmed

TAF4b transcription networks regulating early oocyte differentiation.

FMR1 FAM83D

1.06e-04779235043944
Pubmed

Talin1 has unique expression versus talin 2 in the heart and modifies the hypertrophic response to pressure overload.

TLN1 TLN2

1.06e-04779223266827
Pubmed

A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.

CLIP4 FMR1 SNX6 CLMN TLN1 ANKRD26 ZNF160

1.39e-0449779723414517
Pubmed

The small muscle-specific protein Csl modifies cell shape and promotes myocyte fusion in an insulin-like growth factor 1-dependent manner.

TLN1 TLN2

1.41e-04879211381084
Pubmed

β2 integrin adhesion complexes maintain the integrity of HIV-1 assembly compartments in primary macrophages.

TLN1 TLN2

1.41e-04879222017400
Pubmed

Arginylation-dependent neural crest cell migration is essential for mouse development.

TLN1 TLN2

1.41e-04879220300656
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

CLIP4 TET2 SNX6 ARFGEF2 DYNC2I1 TLN2 ZNF350 HUWE1 ATP1A2 MTMR10 CEP63

1.52e-041285791135914814
Pubmed

C16orf72/HAPSTR1 is a molecular rheostat in an integrated network of stress response pathways.

TLN1 OTUD4 HUWE1 ADD1

1.61e-0411979435776542
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

ESYT2 SMG7 PHF3 TLN1 TLN2

1.66e-0422579512168954
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

RESF1 GAS2L3 CLMN PGAP1 OTUD4 BBS4 ZNF699 HUWE1 HERC1 CEP63

1.70e-041084791011544199
Pubmed

Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.

CLIP4 ESYT2 FAM111A SMG7 GAS2L3 CLMN PHF3 ZNF724

1.73e-0468979836543142
Pubmed

Comparative phenotypic analysis of the two major splice isoforms of phosphatidylinositol phosphate kinase type Iγ in vivo.

TLN1 TLN2

1.82e-04979222976293
Pubmed

Duplication and extensive remodeling shaped POTE family genes encoding proteins containing ankyrin repeat and coiled coil domains.

ANKRD26 POTEA

1.82e-04979216364570
Pubmed

BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.

STAM2 ESYT2 FBXO5 MARK3 TLN1 ANKRD26 DENND4C ADD1

2.07e-0470879839231216
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

INTU RESF1 FMR1 FBXO5 SMG7 CCNB3 ANAPC1 PKP4 CTNNBL1 ITIH4

2.15e-041116791031753913
Pubmed

Cooperative polarization of MCAM/CD146 and ERM family proteins in melanoma.

ESYT2 SNX6 MARK3 PKP4 MTMR10 ADD1

2.23e-0437779638117590
Pubmed

Assembly of the cochlear gap junction macromolecular complex requires connexin 26.

TLN1 TLN2

2.27e-041079224590285
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

STAM2 SMG7 ANAPC1 PHF3 TLN1 HUWE1 ADD1

2.55e-0454979738280479
Pubmed

CEP63 upregulates YAP1 to promote colorectal cancer progression through stabilizing RNA binding protein FXR1.

FMR1 CEP63

2.76e-041179235989368
Pubmed

Systematic analysis of human protein complexes identifies chromosome segregation proteins.

FBXO5 ANAPC1 CWC15 ZNF644 TLN1 CTNNBL1 DYNC2I1 FAM83D TLN2 CEP63

2.83e-041155791020360068
Pubmed

E-cadherin interactome complexity and robustness resolved by quantitative proteomics.

ESYT2 MARK3 CLMN PKP4 TLN1 DENND4C ADD1

3.04e-0456579725468996
Pubmed

The mRNA repressor TRIM71 cooperates with Nonsense-Mediated Decay factors to destabilize the mRNA of CDKN1A/p21.

SMG7 MYB

3.31e-041279231732746
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

INTU MARK3 PHF3 ZNF644 TLN1 OTUD4

3.35e-0440779612693553
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

FMR1 ANAPC1 PKP4 OTUD4 TLN2 HUWE1 TEX10 ITIH4 ADD1

3.35e-0496379928671696
Pubmed

Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.

ANAPC1 CWC15 TLN1 ARFGEF2 TLN2 HUWE1 SEC23B

3.63e-0458279720467437
Pubmed

Human transcription factor protein interaction networks.

CDCA2 TET2 RESF1 SMG7 ZNF644 ZNF724 OTUD4 HERC1 TEX10 SEC23B MYB

3.77e-041429791135140242
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

TET2 RESF1 ANAPC1 ZNF644 HUWE1 DENND4C

3.86e-0441879634709266
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

STAM2 RESF1 SMG7 ANAPC1 ZNF644 ANKRD26 HUWE1

3.86e-0458879738580884
Pubmed

A Role for Mitochondrial Translation in Promotion of Viability in K-Ras Mutant Cells.

FMR1 FBXO5 PHF3 WDR25 TEX10 SEC23B

3.91e-0441979628700943
Pubmed

Emi1 stably binds and inhibits the anaphase-promoting complex/cyclosome as a pseudosubstrate inhibitor.

FBXO5 ANAPC1

3.91e-041379216921029
Pubmed

Functional proteomics mapping of a human signaling pathway.

STAM2 ARFGEF2 ZNF350 HUWE1 HERC1 TEX10 MTMR10

3.98e-0459179715231748
Pubmed

A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.

STAM2 ESYT2 MARK3 PKP4 ANKRD26 ADD1

4.01e-0442179636976175
Pubmed

Chromosomal assignments of 17 structural genes and 11 related DNA fragments in rats (Rattus norvegicus) by Southern blot analysis of rat x mouse somatic cell hybrid clones.

ATP1A2 MYB

4.55e-04147921572638
Pubmed

Targeted ablation of PINCH1 and PINCH2 from murine myocardium results in dilated cardiomyopathy and early postnatal lethality.

TLN1 TLN2

4.55e-041479219652092
Pubmed

Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.

FMR1 PHF3 PKP4 TLN2 SHISA6

4.60e-0428179528706196
Pubmed

Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.

CDCA2 FMR1 ANAPC1 PHF3 HUWE1 TEX10

5.06e-0444079634244565
Pubmed

Talin 1 and 2 are required for myoblast fusion, sarcomere assembly and the maintenance of myotendinous junctions.

TLN1 TLN2

5.25e-041579219793892
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

STAM2 ESYT2 SNX6 MARK3 CLMN CWC15 ZNF644 PKP4 TLN1 ANKRD26 ADD1

5.26e-041487791133957083
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

ESYT2 ANAPC1 MARK3 PHF3 PKP4 TLN1 CTNNBL1 OTUD4 FAM83D TEX10 DUSP11

5.56e-041497791131527615
Pubmed

Loss of alpha3beta1 integrin function results in an altered differentiation program in the mouse submandibular gland.

TLN1 TLN2

5.99e-041679211307167
Pubmed

Proximity interactions of the ubiquitin ligase Mind bomb 1 reveal a role in regulation of epithelial polarity complex proteins.

STAM2 SMG7 ANKRD26 CEP63

6.09e-0416979431462741
Pubmed

Atomic structure of the APC/C and its mechanism of protein ubiquitination.

FBXO5 ANAPC1

6.78e-041779226083744
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

FMR1 ANAPC1 PHF3 TLN1 HUWE1 TEX10 SEC23B

7.18e-0465379722586326
Pubmed

Organization of focal adhesion plaques is disrupted by action of the HIV-1 protease.

TLN1 TLN2

7.61e-041879212119179
Pubmed

Acetylation-Mimic Mutation of TRIM28-Lys304 to Gln Attenuates the Interaction with KRAB-Zinc-Finger Proteins and Affects Gene Expression in Leukemic K562 Cells.

ZNF644 ZNF724 ZNF699 ZNF160

7.86e-0418179437372979
Pubmed

Proximity labeling reveals dynamic changes in the SQSTM1 protein network.

ESYT2 SMG7 ANAPC1 OTUD4 SEC23B

8.49e-0432279539098523
Pubmed

Identification of seven new prostate cancer susceptibility loci through a genome-wide association study.

TET2 NKX3-1

8.50e-041979219767753
Pubmed

Prostate cancer risk-associated variants reported from genome-wide association studies: meta-analysis and their contribution to genetic Variation.

TET2 NKX3-1

9.43e-042079220564319
Pubmed

Spatial proteomics reveal that the protein phosphatase PTP1B interacts with and may modify tyrosine phosphorylation of the rhomboid protease RHBDL4.

STAM2 ESYT2 CLMN TLN1

9.60e-0419179431177093
Pubmed

Interactions of the Antiviral Factor Interferon Gamma-Inducible Protein 16 (IFI16) Mediate Immune Signaling and Herpes Simplex Virus-1 Immunosuppression.

FMR1 SNX6 HUWE1 TEX10 ADD1

9.73e-0433279525693804
Pubmed

Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.

ANAPC1 PHF3 TLN1 CTNNBL1 HUWE1

9.73e-0433279532786267
Pubmed

SIX1 and SIX4 homeoproteins regulate PAX7+ progenitor cell properties during fetal epaxial myogenesis.

TLN1 TLN2

1.04e-032179232591430
Pubmed

The sperm-associated antigen 6 interactome and its role in spermatogenesis.

PKP4 ZFP28 BBS4 FAM217A

1.12e-0319979431146259
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

STAM2 SMG7 CLMN CWC15 TLN1 ZNF724 ANKRD26 ADD1

1.27e-0393479833916271
Pubmed

SPATA2-Mediated Binding of CYLD to HOIP Enables CYLD Recruitment to Signaling Complexes.

TET2 ESYT2 CARD6 OTUD4 FAM83D

1.28e-0335379527545878
InteractionEBAG9 interactions

STAM2 ESYT2 SNX6 MARK3 PKP4 ANKRD26 ARFGEF2 DENND4C SEC23B ADD1

1.56e-073037410int:EBAG9
InteractionDIRAS3 interactions

STAM2 ESYT2 SNX6 MARK3 PKP4 ANKRD26 HUWE1 HERC1

5.27e-06262748int:DIRAS3
Cytoband1p13.3

NBPF4 NBPF6 NBPF5P

2.37e-04697931p13.3
Cytoband7q36.3

ESYT2 DYNC2I1

7.87e-04247927q36.3
Cytoband8p21.2

CDCA2 NKX3-1

8.55e-04257928p21.2
GeneFamilyNeuroblastoma breakpoint family

NBPF4 NBPF6 NBPF5P

3.60e-0523513662
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZNF502 ZNF717 ZSCAN20 ZNF540 ZFP28 ZNF350 ZNF699 ZNF160

8.35e-0471851828
GeneFamilyMitogen-activated protein kinase kinase kinases|RAF family

MAP3K1 MAP3K19

2.07e-0324512654
CoexpressionGSE3982_MAC_VS_BASOPHIL_DN

RESF1 SMG7 CTNNBL1 BBS4 MYB CEP63

2.82e-05198786M5498
CoexpressionGSE2770_IL12_VS_TGFB_AND_IL12_TREATED_ACT_CD4_TCELL_2H_UP

CLIP4 DTWD2 CARD6 ARFGEF2 CEP63

4.07e-05128785M6083
CoexpressionDUTERTRE_ESTRADIOL_RESPONSE_24HR_UP

CDCA2 TET2 FBXO5 GAS2L3 FAM83D IL17RB MYB

5.05e-05323787M2156
CoexpressionZHANG_BREAST_CANCER_PROGENITORS_UP

ANAPC1 PKP4 ANKRD26 ZNF699 ERI2 ZNF160 MYB DUSP11

5.64e-05448788MM1044
CoexpressionGSE13522_WT_VS_IFNG_KO_SKIN_UP

ENAM CCNB3 NKX3-1 ITIH4 SHISA6

5.83e-05138785M2913
CoexpressionREICHERT_MITOSIS_LIN9_TARGETS

CDCA2 FBXO5 ANAPC1

7.04e-0527783M2483
CoexpressionREICHERT_MITOSIS_LIN9_TARGETS

CDCA2 FBXO5 ANAPC1

7.87e-0528783MM1323
CoexpressionAtlasdev gonad_e13.5_F_MeioticGermCell_Oct_top-relative-expression-ranked_1000

ZNF717 LUZP4 ESYT2 FMR1 DTWD2 PGAP1 ANKRD26 ARFGEF2 OTUD4 HUWE1 HERC1 TEX10

2.14e-058207312gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_1000
CoexpressionAtlasDevelopingGonad_e18.5_ovary_emap-12283_top-relative-expression-ranked_500

CLIP4 RESF1 CCNB3 PKP4 CAPS2 HERC1 SHISA6 ADD1

5.42e-05387738gudmap_developingGonad_e18.5_ovary_500
CoexpressionAtlasfacebase_RNAseq_e10.5_MaxArch_2500_K3

CDCA2 C9orf85 TET2 RESF1 FBXO5 ZNF644 ST8SIA2 ANKRD26 DYNC2I1 ERI2 TEX10 ZNF160 MTMR10 SEC23B

7.98e-0512527314facebase_RNAseq_e10.5_MaxArch_2500_K3
CoexpressionAtlasDevelopingGonad_e12.5_ovary_emap-28876_top-relative-expression-ranked_1000

CDCA2 RESF1 GAS2L3 CLMN PKP4 ANKRD26 HUWE1 CAPS2 HERC1 ADD1 MAP3K1

8.94e-058047311gudmap_developingGonad_e12.5_ovary_1000
ToppCellfacs-Lung-24m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l15|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FAM111A SMG7 PGAP1 TEX10 MTMR10

9.44e-06159795999f30c7273ed77b34537621bcfcc7fc30121138
ToppCell(01)_Cycling_Basal_(homeostasis)|World / shred by cell type and Timepoint

CDCA2 FAM111A FBXO5 GAS2L3 FAM83D

1.59e-0517779505c57578142a6662f18b294d5cc11e6efd6b0f8e
ToppCelldroplet-Lung-nan-18m-Myeloid-Proliferating_Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDCA2 INTU GAS2L3 CLMN FAM83D

1.72e-0518079543fd5c498a87bb078d101298b472656f3294686a
ToppCelldroplet-Lung-18m-Hematologic-myeloid-alveolar_macrophage-proliferating_alveolar_macrophage|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CDCA2 INTU GAS2L3 CLMN FAM83D

1.86e-05183795e91f00b75d43ee6293fdd4a129b789cd95f8d11a
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_G2M|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CDCA2 FBXO5 GAS2L3 FAM83D ERI2

2.12e-0518879595d0a796d62ce6d121e2028c378faffc14b35275
ToppCellEndothelial-Endothelial-D_(cycle)|Endothelial / shred on cell class and cell subclass (v4)

CDCA2 FAM111A FBXO5 GAS2L3 FAM83D

2.29e-05191795a3c5a913a99f17633c140ec9ece81b73e59e0715
ToppCellP03-Mesenchymal-developing_mesenchymal_cell-mesenchymal_proliferating_cell|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CDCA2 FAM111A FBXO5 GAS2L3 FAM83D

2.29e-05191795b978afe76754cc56e1672abca27be289bb56375b
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25|PBMC_fresh-frozen / Compartment, severity and other cell annotations on 10x 3' data (130k)

PHF3 ZNF644 PGAP1 ARFGEF2 HERC1

2.29e-051917951ecd9849d14d5ebf3daf610e83fb50820cafd3ed
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Stem-like-NPC-like-NPC-like_Prolif-E|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CDCA2 FBXO5 GAS2L3 FAM83D SHISA6

2.46e-051947957a66bd7d4fc9c6db861cedd2487f241e406869d1
ToppCellTracheal-10x3prime_v2-Epithelial-Epi_submucosal-gland-SMG_Duct|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

ZSCAN20 DTWD2 ZNF699 IL17RB ITIH4

2.52e-05195795fdbb4abc0c79a6aeace71bfa5a5c5576ca39d758
ToppCellNon-neuronal-Dividing-IPC-IPC-div1-28|World / Primary Cells by Cluster

CDCA2 FAM111A FBXO5 GAS2L3 FAM83D

2.78e-05199795787688b68ae5d8768c0a24673ae07ab07616764a
ToppCellNon-neuronal-Dividing-IPC-IPC-div1|World / Primary Cells by Cluster

CDCA2 FAM111A FBXO5 GAS2L3 FAM83D

2.78e-0519979572823f26ecabcae1b514b7629cfce010c97b929a
ToppCellLPS_IL1RA_TNF-Endothelial-Endothelial-FOXM1|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

CDCA2 FBXO5 GAS2L3 ST8SIA2 ERI2

2.85e-052007954cfe08878a6981bf7b3567f9e82192d8f060ddde
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW26-Stem_cells|GW26 / Sample Type, Dataset, Time_group, and Cell type.

CDCA2 FAM111A FBXO5 FAM83D IL17RB

2.85e-05200795a854e19703dc920e48304541e2b06ed013292f3e
ToppCelldistal-Hematologic-Proliferating_Macrophage|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CDCA2 FAM111A FBXO5 FAM83D IL17RB

2.85e-052007953835a8a9739b8cd5bf19c40765ef76907ac1ad38
ToppCelldistal-Hematologic-Proliferating_Macrophage-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CDCA2 FAM111A FBXO5 FAM83D IL17RB

2.85e-052007959c03a8da12d29618f72c429836c1d1bd84a78b12
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW19-Stem_cells|GW19 / Sample Type, Dataset, Time_group, and Cell type.

CDCA2 FMR1 FAM111A FBXO5 ERI2

2.85e-0520079531dd81df9aa754a1e69b905bf9b8ce73ff8175aa
ToppCell3'-GW_trimst-2-SmallIntestine-Mesenchymal-immature_mesenchymal_cell-cycling_stromal|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CDCA2 FAM111A FBXO5 GAS2L3 FAM83D

2.85e-0520079563f9481059be608ddc9fe9c7a8f8503fce9755dd
ToppCelldistal-3-Hematologic-Proliferating_Macrophage|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CDCA2 FAM111A FBXO5 FAM83D IL17RB

2.85e-052007951b65c97e8123d0572d31525d6a10bc7f16857959
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW19-Stem_cells-Neuroepithelial_cell|GW19 / Sample Type, Dataset, Time_group, and Cell type.

CDCA2 FMR1 FAM111A FBXO5 ERI2

2.85e-0520079554174a485a82480726fa06efa6e050ddea77cb3c
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW26-Stem_cells-Neuroepithelial_cell|GW26 / Sample Type, Dataset, Time_group, and Cell type.

CDCA2 FAM111A FBXO5 FAM83D IL17RB

2.85e-05200795203b9a5de4430713da01b3331e69381db449a3a0
ToppCellVE-CD8-naive_CD4|VE / Condition, Cell_class and T cell subcluster

ZSCAN20 PKP4 ZNF724 ITIH4

1.88e-04160794255d2a150bfe19ee3d4d34533feb9c37ce73d225
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C_(NP)-Glut_NP_L5/6_FEZF2-Exc_L5-6_FEZF2_CABP7|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CCNB3 NKX3-1 NBPF5P FAM217A

2.02e-04163794a0c973c1951bcd41c036ac18e1a0c815ed89d4f7
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CDCA2 GAS2L3 FAM83D MYB

2.21e-0416779450c29ea660bf07b890e4ac1a1985d0761d863dee
ToppCell5'-Adult-SmallIntestine-Epithelial-Tuft-related-Tuft|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TET2 CLMN GRK5 IL17RB

2.27e-041687948072d0496b7b730c4601009eaa69ec5366d26d73
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CDCA2 FAM111A GAS2L3 FAM83D

2.27e-04168794d35944fd9fea9934ce1e76b2b35d48e2300cca61
ToppCellPND01-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_G2M|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CDCA2 FAM111A FBXO5 GAS2L3

2.27e-0416879452fd65024af8683db11d931f7563cbe8eb815d1c
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-FOXM1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CDCA2 FBXO5 GAS2L3 ERI2

2.32e-04169794e0607af8ae8609d43e26ff2a2cab92650bfcd5b7
ToppCellPND03-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_G2M|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CDCA2 FBXO5 CTNNBL1 TLN2

2.32e-04169794a1efc20e34a81ae32f8d278a5486811ade03ef24
ToppCellE18.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-Sox9_Epi-Sox9_Epi_G2M|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CDCA2 FBXO5 GAS2L3 FAM83D

2.42e-04171794621f9da0bfa09c86fc89fd26919403e94cd56d2b
ToppCell5'-GW_trimst-1-SmallIntestine-Mesenchymal-fibroblastic|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CDCA2 FAM111A FBXO5 GAS2L3

2.42e-04171794d6114db2292fbb27b39d090d51fd305a135b1ccf
ToppCell5'-GW_trimst-1-SmallIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CDCA2 FAM111A FBXO5 GAS2L3

2.42e-0417179405014cf6746e6663e376fdd681f1b43a7081c603
ToppCellfacs-Lung-Endomucin-3m-Endothelial-Lymphatic_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GAS2L3 FAM83D WDR25 F8

2.48e-04172794b3c4adccc34bb9e4e78e40f4e2e23736c347cc75
ToppCellfacs-Lung-Endomucin-3m-Endothelial-endothelial_cell_of_lymphatic_vessel|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GAS2L3 FAM83D WDR25 F8

2.48e-041727942f1673fcb2356684d60871debb0f159aec553a1c
ToppCelldroplet-Marrow-BM_(NON-STC)-30m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RESF1 FBXO5 TLN2 HERC1

2.48e-0417279431c5710fd7ebb221e703545595f5ec0ee3a32bcf
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Epithelial-neuronal_stem_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDCA2 FBXO5 GAS2L3 FAM83D

2.48e-0417279435c20de4db47dbf31c857d23c7a25cd7f95c085c
ToppCelldroplet-Marrow-BM_(NON-STC)|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RESF1 FBXO5 TLN2 HERC1

2.48e-041727946004327045f03d832fdabe6cb2f8b1b1db57789a
ToppCellfacs-Brain_Myeloid-Cerebellum-3m-Myeloid-nan|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TET2 RESF1 FAM111A MAP3K1

2.53e-04173794869da6a65d1b9b7529c666ec44e3c8ddec2ea408
ToppCellfacs-Brain_Myeloid-Cerebellum-3m-Myeloid|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TET2 RESF1 FAM111A MAP3K1

2.53e-041737940672bd8a4a9d18af343d01f09253fb3388896c10
ToppCellfacs-Brain_Myeloid-Cerebellum-3m|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TET2 RESF1 FAM111A MAP3K1

2.53e-04173794870e091ec30be01a900e1cb8b9ef1880e3b7b50d
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PKP4 HERC1 F8 DENND4C

2.59e-04174794f1fe1f4216748a9562dd03bd48c70b23c7ff4d1d
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CDCA2 FBXO5 GAS2L3 FAM83D

2.59e-041747947b318796728001c17b4043d2b033330c7be40c78
ToppCellPND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CDCA2 FBXO5 GAS2L3 FAM83D

2.70e-0417679475412d58438d71c49a6096bb2ef12b7f349653d8
ToppCellPND10-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_G2M|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CDCA2 FBXO5 GAS2L3 FAM83D

2.76e-041777943081ce5fc66a1bb833719d6c0e0a6fc7115eeb91
ToppCellDividing_Macrophages-IPF_02|World / lung cells shred on cell class, cell subclass, sample id

CDCA2 TRAV8-6 FBXO5 FAM83D

2.82e-041787941893fadac2ec3d5de0a641e57b7b2f962012a9ba
ToppCellfacs-Marrow-KLS-24m-Hematologic-MPP_Fraction_B_+_C|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDCA2 FBXO5 FAM83D IL17RB

2.88e-041797945297f7459b40ca780a1983fecc1bb9c035c7677e
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CDCA2 FBXO5 GAS2L3 FAM83D

2.88e-0417979454191c00b29f53b520cd3243b5791daa4a2c72d7
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ST8SIA2 CAPS2 FAM217A MYB

2.95e-041807940c146e80d55d18b6988dd21b1da635801bd3140c
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_G2M|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CDCA2 FBXO5 GAS2L3 FAM83D

2.95e-041807945e1680088065be14447d5d5465f91f7edd071a1e
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ST8SIA2 CAPS2 FAM217A MYB

2.95e-04180794e9af22beae2f3c7fe213b4e19df84abfd2453433
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal-Deuterosomal_L.0.3.4.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ST8SIA2 CAPS2 FAM217A MYB

2.95e-0418079411455ba704ac73f69b474845136cfecec6a88349
ToppCellP15-Endothelial-proliferative_endothelial_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CDCA2 FBXO5 GAS2L3 FAM83D

3.01e-041817940c5bc1660b8fc1e905ab4230202862de5be46ebd
ToppCellP28-Endothelial-proliferative_endothelial_cell-proliferative_endothelial_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CDCA2 FBXO5 GAS2L3 FAM83D

3.01e-04181794e482fd116c00ff4d8db7be3c06b1bd1ffa2d479d
ToppCellCOVID-19-Heart-Pericyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

CLMN GRK5 ATP1A2 SHISA6

3.01e-0418179433cac65ed1ea5e7bd72250495df4f850b143d5aa
ToppCellP15-Endothelial-proliferative_endothelial_cell-proliferative_endothelial_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CDCA2 FBXO5 GAS2L3 FAM83D

3.01e-04181794f83565f09dd971c5cad2704a4a86bca0accd955e
ToppCellP28-Endothelial-proliferative_endothelial_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CDCA2 FBXO5 GAS2L3 FAM83D

3.01e-041817942be3d44619adb25d339e7a27b500a56e07e8de01
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling-Cycling_Connecting_Tubule_Cell_G2M|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CDCA2 GAS2L3 FAM83D ERI2

3.07e-04182794336cd05e46a741185ce3c59ee67a4b07fa6a5101
ToppCellTCGA-Liver-Primary_Tumor-Hepatocellular_Carcinoma-Hepatocellular_Carcinoma-5|TCGA-Liver / Sample_Type by Project: Shred V9

CDCA2 ZSCAN20 FBXO5 GAS2L3

3.14e-04183794f604a8b62c7088fad8365dbf8d910fc980bd3ba8
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CDCA2 FBXO5 GAS2L3 FAM83D

3.27e-0418579430e041d6f6e310d64809e9d6d93cd30052972f3b
ToppCellwk_20-22-Hematologic-Myeloid-MEP|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

CDCA2 CTNNBL1 FAM83D MYB

3.34e-04186794e6e9135a65da568b3a7d0e378f8ce9ae34483968
ToppCellTuft|World / Class top

CLMN WDR25 ATP1A2 IL17RB

3.34e-04186794f4d83f15ab7b49c0920a322cd832413ece7c9948
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1|TCGA-Pancreas / Sample_Type by Project: Shred V9

STAM2 RESF1 ZNF644 MAP3K1

3.34e-0418679403db813598b67b1e08f759758a1c2023396921fa
ToppCellTuft-tuft-2|World / Class top

CLMN WDR25 ATP1A2 IL17RB

3.40e-041877944ec6eee866619dfe13c84f5d2e812bb380d37139
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CDCA2 FBXO5 GAS2L3 FAM83D

3.40e-041877949351fa87b69a951af85b10bf91fe9b1cce8c0517
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Epithelial-neuronal_stem_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDCA2 GAS2L3 ST8SIA2 TEX10

3.40e-04187794a2076599b33ae6750961b573bfebcb9036fa4ee8
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Epithelial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDCA2 GAS2L3 ST8SIA2 TEX10

3.40e-0418779438ee33295a21db4aae5ba085df033db9693e41c6
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Epithelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDCA2 GAS2L3 ST8SIA2 TEX10

3.40e-04187794dbcec24d2c852964736c78e9d81650bff5c455ae
ToppCellE15.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_proliferating_cell|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CDCA2 FBXO5 GAS2L3 FAM83D

3.54e-04189794d049f33115610bda4489968759f754730698b9cd
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

ESYT2 PHF3 PGAP1 MAP3K1

3.62e-0419079491ba66d4b56c59523485b17738e93f14bb00afa4
ToppCell5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-immature_mesenchymal_cell-cycling_stromal|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CDCA2 FBXO5 GAS2L3 FAM83D

3.62e-04190794cd37ccd30c27cf65eda0a9165f35b7672f5acaf6
ToppCellPBMC-Severe-Myeloid-Neutrophil-Neutrophil-Neu_4|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

STAM2 CARD6 ERI2 MYB

3.62e-041907943f0c7d130f66faea778fe567604edf1b4cdf85b3
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-AC-like-AC-like_Prolif-D|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CDCA2 GAS2L3 FAM83D ZNF699

3.69e-0419179414144e0b0c12757358c9aa5dfc9b7edb2edde5c7
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_cycling-mes_proliferating2_(11)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

CDCA2 FBXO5 GAS2L3 FAM83D

3.69e-041917940ba5b112a82e489f5a21966f78a403a7436ce73b
ToppCellE17.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_proliferating_cell|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CDCA2 FBXO5 GAS2L3 FAM83D

3.69e-04191794f764cc21fef87ebad765011098f647ae1bdf6158
ToppCell(3)_Macrophage_Dividing|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

CDCA2 FAM111A ERI2 IL17RB

3.69e-04191794b42f0b89bb94fd43786ff50f1caeb3ebfbbb43fd
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_cycling-mes_proliferating2_(11)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

CDCA2 FBXO5 GAS2L3 FAM83D

3.76e-0419279427723f4e320e49d4a3daafa2d8d3946ff79fab64
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_cycling-mes_proliferating2_(11)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

CDCA2 FBXO5 GAS2L3 FAM83D

3.76e-04192794026f3e38970bea1e6e8d76a4e2becdfb8484b2ff
ToppCell10x_3'_v2v3-Neoplastic-Stem-like-NPC-like-NPC-like_Prolif-D|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CDCA2 FBXO5 GAS2L3 FAM83D

3.76e-04192794f518839ecd9377537a414e8798766f7d91eafeac
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_cycling-mes_proliferating2_(11)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

CDCA2 FBXO5 GAS2L3 FAM83D

3.76e-041927940a54c79dcfdeb99e3b512d42b22359618cfd17e9
ToppCellDividing_Macrophages-SSc-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

CDCA2 FAM111A FBXO5 FAM83D

3.76e-04192794741bd0c2b0a7ce3fcb1610ce8bdacaf9a803c212
ToppCelldroplet-Skin-nan-21m-Epithelial-stem_cell_of_epidermis|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDCA2 FBXO5 GAS2L3 FAM83D

3.76e-0419279496f23d6e8604d1cb24910d3118d8171b57c93e14
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Stem-like-NPC-like-NPC-like_Prolif-D|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CDCA2 FBXO5 GAS2L3 FAM83D

3.76e-0419279490d25b0b38f1cd7a98c76c1f9e38166da6d7a316
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Stem-like-NPC-like-NPC-like_Prolif|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CDCA2 FBXO5 GAS2L3 FAM83D

3.76e-04192794849ac3c115e6f913e68ca050c308bc4c32cf662b
ToppCellP07-Mesenchymal-developing_mesenchymal_cell-mesenchymal_proliferating_cell|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CDCA2 FBXO5 GAS2L3 FAM83D

3.76e-041927945ef79faddb433c09ff36660d8bf7a3af5a67bf1d
ToppCellPBMC-Severe-Myeloid-Neutrophil-Neutrophil-Neu_4|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

STAM2 CARD6 ERI2 MYB

3.76e-04192794c09dcc73ff9c3855a0f3d7bfa0d5c99c09a117f2
ToppCellP07-Endothelial-proliferative_endothelial_cell|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CDCA2 FAM111A FBXO5 FAM83D

3.84e-041937941e95ef29357969ee385b4717c0b5a497390ac260
ToppCellPND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CDCA2 FBXO5 GAS2L3 FAM83D

3.84e-04193794a332dfdcc48c405020014e644aa4d14fda98cc86
ToppCellNS-moderate-d_0-4|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

INTU CLMN DYNC2I1 MAP3K19

3.84e-04193794ea345d34440b25f65358a53dc72831998d1c3620
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_proliferating-|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CDCA2 FAM111A FBXO5 GAS2L3

3.84e-04193794e45ce9cf8421512b57f157c24b64793b47b4ba4b
ToppCellP07-Endothelial-proliferative_endothelial_cell-proliferative_endothelial_cell|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CDCA2 FAM111A FBXO5 FAM83D

3.84e-041937940f21fb8b35f89f4c1c8109d1a4d3d08a452f9edd
ToppCell(07)_Brush|World / shred by cell type and Timepoint

CLMN WDR25 ATP1A2 IL17RB

3.84e-041937949af9d22a130ff97a9c37142a65e841b056d08640
ToppCellP03-Endothelial-proliferative_endothelial_cell|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CDCA2 FAM111A FBXO5 FAM83D

3.91e-0419479422bcfb0f3f73608feb22c0847ab4d34f87aeede0
ToppCell(3)_Chondrocytes-(33)_Chondro-prol/rest|(3)_Chondrocytes / Cell class and subclass of bone marrow stroma cells in homeostatis

CDCA2 FAM111A FBXO5 GAS2L3

3.91e-041947944a207630d72059345b10010f5cfd3b1462458324
ToppCellP03-Endothelial-proliferative_endothelial_cell-proliferative_endothelial_cell|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CDCA2 FAM111A FBXO5 FAM83D

3.91e-041947945e56ce9b9fe0721be3a9e6efe1422599bb867721
ToppCell(7)_Epithelial_cells-(7)_Epithelial-J_(AT1-AT2_progenitors)|(7)_Epithelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)

CDCA2 FAM111A FAM83D IL17RB

3.91e-041947944d6ae2b25db11a4ae6dadee83be5c8c05b1225c3
ToppCellPND03-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CDCA2 FBXO5 GAS2L3 FAM83D

3.91e-041947943a49c7c86036e09a8cd0114988380d04ad1a26fb
ToppCellCV-Severe-6|CV / Virus stimulation, Condition and Cluster

RESF1 TLN1 ZNF160 ADD1

3.99e-0419579469095c6ce2a7e763afa543c10d5710e0c3dda769
ToppCell3'-GW_trimst-1-LargeIntestine-Mesenchymal-immature_mesenchymal_cell-cycling_stromal|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CDCA2 FBXO5 GAS2L3 FAM83D

3.99e-04195794742c82c86487314cdb3178012004adb1164bcbdb
ToppCellPND03-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_G2M|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CDCA2 FBXO5 GAS2L3 FAM83D

3.99e-041957945790b47b0e028e49b99bda8d6d9e80ac79208cdf
ToppCellE18.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_G2M|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CDCA2 FBXO5 GAS2L3 FAM83D

3.99e-04195794a838bddeed487154791b69d27a68673783ff63c0
DrugAcetylsalicylsalicylic acid [530-75-6]; Down 200; 13.4uM; PC3; HT_HG-U133A

STAM2 PHF3 PKP4 BBS4 NKX3-1 F8 CEP63

4.35e-062007572061_DN
Drugcylindrospermopsin

CYLC1 ST8SIA2 ADD1

2.70e-0518753CID000115005
DrugDisulfiram [97-77-8]; Up 200; 13.4uM; HL60; HG-U133A

STAM2 RESF1 FMR1 FAM111A FBXO5 MARK3

3.78e-051897561369_UP
DrugAlfaxalone [23930-19-0]; Down 200; 12uM; MCF7; HT_HG-U133A

CLMN PGAP1 BBS4 F8 MAP3K1 CEP63

4.50e-051957566514_DN
Drugleukotoxin B (12,13-EODE); Up 200; 0.2uM; MCF7; HT_HG-U133A_EA

RESF1 MARK3 CLMN DYNC2I1 BBS4 CEP63

4.50e-051957561108_UP
DrugSulfasalazine [599-79-1]; Down 200; 10uM; MCF7; HT_HG-U133A

GRK5 TLN1 PGAP1 ANKRD26 MAP3K1 MYB

4.63e-051967565446_DN
DrugClorgyline hydrochloride [17780-75-5]; Down 200; 13uM; MCF7; HT_HG-U133A

STAM2 CLMN GRK5 TLN1 ARFGEF2 ZNF350

4.63e-051967565005_DN
DrugAdiphenine hydrochloride [50-42-0]; Up 200; 11.4uM; HL60; HT_HG-U133A

STAM2 PHF3 PGAP1 BBS4 F8 MYB

4.63e-051967561872_UP
DrugAtracurium besylate [64228-81-5]; Up 200; 3.2uM; PC3; HT_HG-U133A

STAM2 FMR1 SMG7 PGAP1 DYNC2I1 BBS4

4.77e-051977561824_UP
DrugPheniramine maleate [132-20-7]; Up 200; 11.2uM; HL60; HG-U133A

FBXO5 SMG7 TLN1 ZNF160 SEC23B CEP63

4.77e-051977561992_UP
DrugCyproterone acetate [427-51-0]; Down 200; 9.6uM; MCF7; HT_HG-U133A

CYLC1 STAM2 CLMN ARFGEF2 OTUD4 MAP3K1

5.04e-051997566806_DN
DrugIsotretinoin [4759-48-2]; Down 200; 13.4uM; PC3; HT_HG-U133A

SMG7 PGAP1 ARFGEF2 BBS4 ZNF350 MYB

5.19e-052007567315_DN
Diseasemorbid obesity (is_implicated_in)

CTNNBL1 BBS4

1.81e-048762DOID:11981 (is_implicated_in)
Diseasevenous thromboembolism, plasminogen activator inhibitor 1 measurement

GRK5 ZNF160

1.33e-0321762EFO_0004286, EFO_0004792
Diseasevenous thromboembolism, tissue plasminogen activator measurement

GRK5 ZNF160

1.60e-0323762EFO_0004286, EFO_0004791
Diseaseaggressive behavior

ARFGEF2 ZNF160

1.89e-0325762EFO_0003015
Diseasecorpus callosum volume measurement

DTWD2 TLN1 ADD1

2.22e-03100763EFO_0010299

Protein segments in the cluster

PeptideGeneStartEntry
DRFKSHPSLSTTNQQ

PKP4

1021

Q99569
LPEHKSSTFNRVNAN

ERI2

501

A8K979
THVSKKTLNPVFDQS

ESYT2

841

A0FGR8
KHQTTSTSKPASFQQ

BBS4

446

Q96RK4
QQLSVFKRHNPSTAE

CTNNBL1

291

Q8WYA6
ENTKSNVTHKQSPRN

CAPS2

156

Q9BXY5
NKVLSNNASSQKPTH

BCORP1

36

Q8N888
VSPKFVRLKHSQAQS

ARFGEF2

226

Q9Y6D5
PSHTKIKYRQTTQDA

CWC15

36

Q9P013
YKEERIPKHSSQNSN

ANKRD26

221

Q9UPS8
TSSLEHRQSYPKKQN

CLIP4

431

Q8N3C7
NSLFRHPKQVQLKTS

DTWD2

191

Q8NBA8
FSQEPSALQKKHTTQ

CCNB3

431

Q8WWL7
AHIRFKPTLSQQQKS

ITIH4

211

Q14624
NSNQPHRSTKITFKE

NBPF4

221

Q96M43
SQKFSSEHKNLSRTP

OTUD4

401

Q01804
RQNHSKKESPSRQQS

LUZP4

51

Q9P127
VQRFNISSHNQSPKR

ANAPC1

366

Q9H1A4
NSPHQRVKQSTEFAI

MTMR10

506

Q9NXD2
NNQSTLKKLTFEPHR

HERC1

441

Q15751
QVFEPHQKKQTRASV

IL17RB

221

Q9NRM6
HKKQSFVLSPFSTQE

DYNC2I1

776

Q8WVS4
SKKTNTEFLHTKNNP

CYLC1

206

P35663
QSSNKFDHLTNRKPQ

FAM83D

306

Q9H4H8
RHPSTRQKQFNATTI

F8

766

P00451
VTTPFHRDQTVKTQK

MYB

431

P10242
LQNHTFTENIKPFTT

POMGNT2

541

Q8NAT1
VFPSHFTQQRTKETN

HUWE1

3346

Q7Z6Z7
TSHPRQKKTQSNTSD

INTU

271

Q9ULD6
NHTEIVFARTSPQQK

ATP1A2

681

P50993
NSTHFSQPNSTKVQR

FMR1

361

Q06787
QFKSDQSNPSTVKHS

CARD6

941

Q9BX69
SLQQSVRKFSENPHV

DUSP11

306

O75319
RVTENNNKFSPHAST

FBXO5

301

Q9UKT4
KQNDRIFKPTHSRTT

CEP63

536

Q96MT8
QTAPKSAQTVAKSQH

GAS2L3

626

Q86XJ1
ATTNTQAQRFHSPKK

FAM111A

51

Q96PZ2
FTGRFKQQTPSRTHK

DENND4C

1306

Q5VZ89
PHHKVQRSVSSSQKQ

MARK3

401

P27448
FSSSNNHEKISSPKV

CDCA2

486

Q69YH5
KHSSQASDRSKFQPQ

KIAA1210

1331

Q9ULL0
KSSAPKRHNKTDQTQ

ENAM

106

Q9NRM1
VHSQKSTQNSKQGIF

FAM217A

71

Q8IXS0
KRQHQNNSKSSPSSK

GRK5

556

P34947
SRPQKHQNTFSFKND

C9orf85

11

Q96MD7
QSTHRTQKPKKQSFP

MAP3K19

601

Q56UN5
RKSRKHENQQFPNTE

POTEA

376

Q6S8J7
SASPQTQRKFSLQFH

MAP3K1

1016

Q13233
NSNQPHRSTKITFKE

NBPF5P

221

Q86XG9
NSNQPHRSTKITFKE

NBPF6

221

Q5VWK0
HVTQNSRPLKTKTAF

RESF1

1326

Q9HCM1
NKQTHTSAIVKPQSS

SMG7

131

Q92540
SNESIKHNIQPASSK

ST8SIA2

71

Q92186
SSKNHYTPVRTAKQT

SHISA6

251

Q6ZSJ9
KQPQKRSRAAFSHTQ

NKX3-1

121

Q99801
TTFKNSQPVNPKHSR

PGAP1

771

Q75T13
QARFLLSKVNPSQTH

SEC23B

716

Q15437
SPLRHSFQKQQREKT

ADD1

431

P35611
TSQAFNKVPSPHETK

CLMN

576

Q96JQ2
QFRQEPITHNKTLSK

ZFP28

356

Q8NHY6
PSFTLNQRIHNSEKS

ZNF540

156

Q8NDQ6
QQIPSSVQTHRSKKY

ZNF160

221

Q9HCG1
KFSNSNRHKTEKNPF

ZNF724

156

A8MTY0
STNVKNVAKPSTIFH

ZNF826P

66

Q6ZT77
SPFSEKLRTCHQNSQ

ZSCAN20

501

P17040
TTNPTAKRQFVQSAK

TLN1

1516

Q9Y490
FNKSQTSFHLRKPSV

TRAV8-6

86

A0A0B4J262
SFTTVLHKQRNKPQQ

PHF3

1401

Q92576
QNATPTNFKTKTIHL

TEX10

26

Q9NXF1
QKQQHTETKSLYPSS

STAM2

181

O75886
HTKSSLPNFKQNEFS

SNX6

51

Q9UNH7
STKSQFISPKHQKTR

ZNF350

186

Q9GZX5
KTFRQKSNLSTHQGT

ZNF717

626

Q9BY31
QNSSPHKNVTIKSSV

ZNF644

701

Q9H582
KAFTQSTPLTKHQRI

ZNF502

386

Q8TBZ5
SKTANPVAKRHFVQS

TLN2

1516

Q9Y4G6
QVKLSRNFPKSSFHA

WDR25

136

Q64LD2
PTSLNTHVKNQSREK

ZNF699

431

Q32M78
PRQAYTQKTTQLEHK

TET2

616

Q6N021