Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionGTPase activator activity

TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D LARS1 TBC1D3C TBC1D3B RIN2 TBC1D3I TBC1D3G TBC1D3K TBC1D3F

1.83e-0827912313GO:0005096
GeneOntologyMolecularFunctionnucleoside-triphosphatase regulator activity

TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D LARS1 TBC1D3C TBC1D3B RIN2 EIF2B3 TBC1D3I TBC1D3G TBC1D3K RASGRP2 TBC1D3F

5.42e-0750712315GO:0060589
GeneOntologyMolecularFunctionGTPase regulator activity

TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D LARS1 TBC1D3C TBC1D3B RIN2 EIF2B3 TBC1D3I TBC1D3G TBC1D3K RASGRP2 TBC1D3F

5.42e-0750712315GO:0030695
GeneOntologyMolecularFunctionpeptide lactyltransferase (CoA-dependent) activity

CREBBP EP300

3.76e-0521232GO:0120300
GeneOntologyMolecularFunctionhistone H3K27 acetyltransferase activity

CREBBP EP300

3.76e-0521232GO:0044017
GeneOntologyMolecularFunctionUDP-glycosyltransferase activity

MGAT4A EXT2 RXYLT1 B3GNT8 MGAT1 POGLUT1 GYS1

4.57e-051531237GO:0008194
GeneOntologyMolecularFunctionhexosyltransferase activity

MGAT4A EXT2 GBA2 PIGZ B3GNT8 MGAT1 POGLUT1 GYS1

4.96e-052111238GO:0016758
GeneOntologyMolecularFunctionenzyme activator activity

TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D LARS1 TBC1D3C TBC1D3B FZR1 RIN2 TBC1D3I TBC1D3G TBC1D3K TBC1D3F

5.29e-0565612314GO:0008047
GeneOntologyMolecularFunctionglycosyltransferase activity

MGAT4A EXT2 RXYLT1 GBA2 PIGZ B3GNT8 MGAT1 POGLUT1 GYS1

7.47e-052881239GO:0016757
GeneOntologyMolecularFunctionhistone H3K18 acetyltransferase activity

CREBBP EP300

1.12e-0431232GO:0043993
GeneOntologyMolecularFunctionacetylglucosaminyltransferase activity

MGAT4A EXT2 B3GNT8 MGAT1

1.99e-04471234GO:0008375
GeneOntologyMolecularFunctionbeta-adrenergic receptor kinase activity

GRK2 GRK3

2.24e-0441232GO:0047696
GeneOntologyMolecularFunctionhistone acetyltransferase activity

CREBBP TAF1 TAF1L EP300

2.74e-04511234GO:0004402
GeneOntologyMolecularFunctionglucosyltransferase activity

GBA2 POGLUT1 GYS1

3.22e-04221233GO:0046527
GeneOntologyMolecularFunctionpeptide-lysine-N-acetyltransferase activity

CREBBP TAF1 TAF1L EP300

3.67e-04551234GO:0061733
GeneOntologyMolecularFunctionH3K27me3 modified histone binding

TAF1 TAF1L

3.72e-0451232GO:0061628
GeneOntologyMolecularFunctionN-acyltransferase activity

PLA2G4E CREBBP TAF1 TAF1L EP300

4.23e-041021235GO:0016410
GeneOntologyMolecularFunctionpeptide N-acetyltransferase activity

CREBBP TAF1 TAF1L EP300

5.12e-04601234GO:0034212
GeneOntologyMolecularFunctionhistone modifying activity

BAZ1B CREBBP BAP1 KMT2D TAF1 TAF1L EP300

5.48e-042291237GO:0140993
GeneOntologyMolecularFunctionRNA polymerase II general transcription initiation factor binding

CREBBP TAF1 TAF1L

5.99e-04271233GO:0001091
GeneOntologyMolecularFunctionG protein-coupled receptor kinase activity

GRK2 GRK3

7.75e-0471232GO:0004703
GeneOntologyMolecularFunctionacetylation-dependent protein binding

TAF1 TAF1L EP300

9.04e-04311233GO:0140033
GeneOntologyMolecularFunctionp53 binding

CREBBP TAF1 TAF1L EP300

1.31e-03771234GO:0002039
GeneOntologyMolecularFunctionRNA polymerase I general transcription initiation factor activity

TAF1 TAF1L

1.32e-0391232GO:0001181
GeneOntologyMolecularFunctionN-acetyltransferase activity

CREBBP TAF1 TAF1L EP300

1.38e-03781234GO:0008080
GeneOntologyMolecularFunctionpromoter-specific chromatin binding

IRF3 TAF1 TAF1L EP300

1.73e-03831234GO:1990841
GeneOntologyMolecularFunctionUDP-xylosyltransferase activity

RXYLT1 POGLUT1

2.00e-03111232GO:0035252
GeneOntologyMolecularFunctionxylosyltransferase activity

RXYLT1 POGLUT1

2.00e-03111232GO:0042285
GeneOntologyBiologicalProcessactivation of GTPase activity

TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3I TBC1D3G TBC1D3K TBC1D3F

7.16e-1110912711GO:0090630
GeneOntologyBiologicalProcesspositive regulation of GTPase activity

TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D LARS1 TBC1D3C TBC1D3B TBC1D3I TBC1D3G TBC1D3K RASGRP2 TBC1D3F

3.72e-0924412713GO:0043547
GeneOntologyBiologicalProcessregulation of GTPase activity

TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D LARS1 TBC1D3C TBC1D3B TBC1D3I TBC1D3G TBC1D3K RASGRP2 TBC1D3F

1.57e-0733512713GO:0043087
GeneOntologyBiologicalProcesspositive regulation of hydrolase activity

TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D LARS1 TBC1D3C TBC1D3B TBC1D3I TBC1D3G TBC1D3K RASGRP2 TBC1D3F

1.29e-0549912713GO:0051345
GeneOntologyBiologicalProcessglycosylation

FKRP MGAT4A EXT2 RXYLT1 GBA2 B3GNT8 MGAT1 POGLUT1 CHST4

4.56e-052701279GO:0070085
GeneOntologyBiologicalProcesspositive regulation of molecular function

KCTD7 TBC1D3E TCAF1 TBC1D3 ANGPT1 TBC1D3H TBC1D3L TBC1D3D LARS1 TBC1D3C CREBBP TBC1D3B GHR FZR1 TRAF4 TAF1 TBC1D3I TBC1D3G EP300 TBC1D3K RASGRP2 TBC1D3F

5.83e-05143012722GO:0044093
GeneOntologyBiologicalProcesscellular response to L-leucine

UBR1 LARS1 EP300

6.23e-05131273GO:0071233
GeneOntologyBiologicalProcessglycoprotein metabolic process

FKRP MGAT4A EXT2 RXYLT1 HPSE B3GNT8 MGAT1 POGLUT1 CHST4 DSEL EP300

7.25e-0543012711GO:0009100
GeneOntologyBiologicalProcessglycoprotein biosynthetic process

FKRP MGAT4A EXT2 RXYLT1 B3GNT8 MGAT1 POGLUT1 CHST4 DSEL EP300

7.41e-0535712710GO:0009101
GeneOntologyBiologicalProcessregulation of autophagosome size

DNAJC16 CLN3

1.12e-0431272GO:0016243
GeneOntologyBiologicalProcessresponse to L-leucine

UBR1 LARS1 EP300

1.20e-04161273GO:0043201
GeneOntologyBiologicalProcessheparin metabolic process

ANGPT1 EXT2 HPSE

1.46e-04171273GO:0030202
GeneOntologyBiologicalProcessmacromolecule glycosylation

FKRP MGAT4A EXT2 RXYLT1 B3GNT8 MGAT1 POGLUT1 CHST4

1.70e-042521278GO:0043413
GeneOntologyBiologicalProcessprotein glycosylation

FKRP MGAT4A EXT2 RXYLT1 B3GNT8 MGAT1 POGLUT1 CHST4

1.70e-042521278GO:0006486
GeneOntologyBiologicalProcesspositive regulation of catalytic activity

TBC1D3E TBC1D3 ANGPT1 TBC1D3H TBC1D3L TBC1D3D LARS1 TBC1D3C TBC1D3B GHR FZR1 TRAF4 TBC1D3I TBC1D3G TBC1D3K RASGRP2 TBC1D3F

1.91e-04102812717GO:0043085
GeneOntologyBiologicalProcessN-terminal peptidyl-lysine acetylation

CREBBP EP300

2.24e-0441272GO:0018076
HumanPhenoPilomatrixoma

CREBBP KMT2D EP300

5.22e-059453HP:0030434
HumanPhenoAbnormal nasal dorsum morphology

SLC25A24 UBR1 RPGRIP1L NUP85 ITGA8 LBR CREBBP GHR KMT2D EP300

7.03e-052624510HP:0011119
HumanPhenoPlantar crease between first and second toes

CREBBP EP300

7.63e-052452HP:0008107
HumanPhenoAortic isthmus hypoplasia

CREBBP EP300

7.63e-052452HP:0034227
HumanPhenoHigh axial triradius

CREBBP EP300

7.63e-052452HP:0001042
HumanPhenoInvoluntary movements

KCTD7 CACNA1B CACNA1S PDCD1 RPGRIP1L OXR1 FKRP MARS1 BAZ1B EXT2 GBA2 CREBBP CHRNA2 BAP1 FZR1 CLPB MYH14 CLN3 ZFYVE26 TAF1 SELENOI RMND1 EP300

9.89e-0512484523HP:0004305
HumanPhenoAbnormal nasolacrimal system morphology

SLC25A24 UBR1 CREBBP KMT2D TAF1 EP300

9.96e-0587456HP:0000614
HumanPhenoParietal foramina

EXT2 CREBBP EP300

2.19e-0414453HP:0002697
HumanPhenoLaryngeal cartilage malformation

CREBBP EP300

2.28e-043452HP:0008752
HumanPhenoPhobia

CREBBP EP300

2.28e-043452HP:5200232
HumanPhenoAgoraphobia

CREBBP EP300

2.28e-043452HP:0000756
HumanPhenoHumoral immunodeficiency

CREBBP EP300

2.28e-043452HP:0005363
HumanPhenoProminent nasal septum

CREBBP EP300

2.28e-043452HP:0005322
HumanPhenoRadial deviation of thumb terminal phalanx

CREBBP EP300

2.28e-043452HP:0005895
DomainTBC

TBC1D3E TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B USP6 TBC1D3I TBC1D3G TBC1D3K TBC1D3F

1.51e-144912311SM00164
DomainRabGAP-TBC

TBC1D3E TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B USP6 TBC1D3I TBC1D3G TBC1D3K TBC1D3F

3.87e-145312311PF00566
DomainRab-GTPase-TBC_dom

TBC1D3E TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B USP6 TBC1D3I TBC1D3G TBC1D3K TBC1D3F

6.00e-145512311IPR000195
DomainTBC_RABGAP

TBC1D3E TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B USP6 TBC1D3I TBC1D3G TBC1D3K TBC1D3F

6.00e-145512311PS50086
DomainBROMODOMAIN_1

BAZ1B CREBBP TRIM66 TAF1 TAF1L EP300

1.42e-07371236PS00633
DomainBromodomain

BAZ1B CREBBP TRIM66 TAF1 TAF1L EP300

1.68e-07381236PF00439
DomainBROMODOMAIN_2

BAZ1B CREBBP TRIM66 TAF1 TAF1L EP300

2.69e-07411236PS50014
DomainBromodomain

BAZ1B CREBBP TRIM66 TAF1 TAF1L EP300

3.12e-07421236IPR001487
DomainBROMO

BAZ1B CREBBP TRIM66 TAF1 TAF1L EP300

3.12e-07421236SM00297
Domain-

BAZ1B CREBBP TRIM66 TAF1 TAF1L EP300

3.12e-074212361.20.920.10
DomainBromodomain_CS

BAZ1B CREBBP TAF1 TAF1L EP300

6.72e-07261235IPR018359
DomainNuc_rcpt_coact_CREBbp

CREBBP EP300

4.30e-0521232IPR014744
DomainTFIID_sub1_DUF3591

TAF1 TAF1L

4.30e-0521232IPR022591
DomainZnF_TAZ

CREBBP EP300

4.30e-0521232SM00551
DomainCAPS

CADPS CADPS2

4.30e-0521232IPR033227
Domain-

CREBBP EP300

4.30e-05212321.20.1020.10
DomainRING_CBP-p300

CREBBP EP300

4.30e-0521232IPR010303
Domain-

CREBBP EP300

4.30e-05212321.10.1630.10
DomainCreb_binding

CREBBP EP300

4.30e-0521232PF09030
DomainTBP-binding

TAF1 TAF1L

4.30e-0521232PF09247
Domainzf-TAZ

CREBBP EP300

4.30e-0521232PF02135
DomainZF_TAZ

CREBBP EP300

4.30e-0521232PS50134
DomainDUF3591

TAF1 TAF1L

4.30e-0521232PF12157
DomainM60-like

TCAF2 TCAF1

4.30e-0521232SM01276
DomainKAT11

CREBBP EP300

4.30e-0521232SM01250
DomainZnf_TAZ

CREBBP EP300

4.30e-0521232IPR000197
DomainKIX

CREBBP EP300

4.30e-0521232PF02172
DomainTAF_II_230-bd

TAF1 TAF1L

4.30e-0521232IPR009067
DomainHAT_KAT11

CREBBP EP300

4.30e-0521232PF08214
DomainKIX

CREBBP EP300

4.30e-0521232PS50952
DomainCBP_P300_HAT

CREBBP EP300

4.30e-0521232IPR031162
DomainPeptidase_M60_dom

TCAF2 TCAF1

4.30e-0521232IPR031161
Domain-

TAF1 TAF1L

4.30e-05212321.10.1100.10
DomainDUF902

CREBBP EP300

4.30e-0521232PF06001
DomainPeptidase_M60

TCAF2 TCAF1

4.30e-0521232PF13402
Domain-

CREBBP EP300

4.30e-05212321.10.246.20
DomainHistone_AcTrfase_Rtt109/CBP

CREBBP EP300

4.30e-0521232IPR013178
DomainKIX_dom

CREBBP EP300

4.30e-0521232IPR003101
DomainTAF1_animal

TAF1 TAF1L

4.30e-0521232IPR011177
DomainCBP_P300_HAT

CREBBP EP300

4.30e-0521232PS51727
DomainPEPTIDASE_M60

TCAF2 TCAF1

4.30e-0521232PS51723
DomainExostosin

EXT2 RXYLT1

4.25e-0451232PF03016
DomainExostosin

EXT2 RXYLT1

4.25e-0451232IPR004263
DomainDUF1041

CADPS CADPS2

4.25e-0451232SM01145
DomainNuc_rcpt_coact

CREBBP EP300

6.34e-0461232IPR009110
DomainMunc13_1

CADPS CADPS2

8.84e-0471232IPR014770
DomainMHD1

CADPS CADPS2

8.84e-0471232PS51258
DomainCa_chan_IQ

CACNA1B CACNA1S

8.84e-0471232SM01062
DomainCa_chan_IQ

CACNA1B CACNA1S

8.84e-0471232PF08763
DomainDUF1041

CADPS CADPS2

8.84e-0471232PF06292
DomainVDCC_a1su_IQ

CACNA1B CACNA1S

8.84e-0471232IPR014873
DomainGPCR_kinase

GRK2 GRK3

8.84e-0471232IPR000239
DomainGPHH

CACNA1B CACNA1S

8.84e-0471232PF16905
DomainCAPS_dom

CADPS CADPS2

8.84e-0471232IPR010439
DomainGPHH_dom

CACNA1B CACNA1S

8.84e-0471232IPR031649
DomainC2

RPGRIP1L WWP2 PLA2G4E CADPS CADPS2

1.75e-031311235PF00168
DomainVDCCAlpha1

CACNA1B CACNA1S

1.87e-03101232IPR002077
DomainC2

RPGRIP1L WWP2 PLA2G4E CADPS CADPS2

2.14e-031371235SM00239
Domain-

MARS1 LARS1

2.28e-031112321.10.730.10
DomainC2

RPGRIP1L WWP2 PLA2G4E CADPS CADPS2

2.50e-031421235PS50004
DomainClass_I_gatase-like

TCAF2 TCAF1

2.72e-03121232IPR029062
DomainOLF

OLFML2B OLFML2A

3.20e-03131232PF02191
DomainOLF

OLFML2B OLFML2A

3.20e-03131232PS51132
DomainOlfac-like_dom

OLFML2B OLFML2A

3.20e-03131232IPR003112
DomainOLF

OLFML2B OLFML2A

3.20e-03131232SM00284
DomainDynein_heavy_chain_D4_dom

DNAH3 DNAH14

3.72e-03141232IPR024317
DomainDynein_HC_stalk

DNAH3 DNAH14

3.72e-03141232IPR024743
DomainMT

DNAH3 DNAH14

3.72e-03141232PF12777
DomainAAA_8

DNAH3 DNAH14

3.72e-03141232PF12780
DomainDHC_fam

DNAH3 DNAH14

4.27e-03151232IPR026983
DomainDynein_heavy

DNAH3 DNAH14

4.27e-03151232PF03028
DomainDynein_heavy_dom

DNAH3 DNAH14

4.27e-03151232IPR004273
DomaintRNAsynth_Ia_anticodon-bd

MARS1 LARS1

4.27e-03151232IPR009080
Domainfn3

IL20RB GHR PTPRB CNTN3 CNTN1

4.39e-031621235PF00041
DomainC2_dom

RPGRIP1L WWP2 PLA2G4E CADPS CADPS2

4.62e-031641235IPR000008
Domainaa-tRNA-synth_I_CS

MARS1 LARS1

6.14e-03181232IPR001412
DomainZF_ZZ_2

CREBBP EP300

6.14e-03181232PS50135
DomainZF_ZZ_1

CREBBP EP300

6.14e-03181232PS01357
DomainZZ

CREBBP EP300

6.14e-03181232PF00569
DomainChannel_four-helix_dom

CACNA1B CACNA1S SLC9C2

6.30e-03571233IPR027359
Domain-

CACNA1B CACNA1S SLC9C2

6.30e-035712331.20.120.350
PathwayWP_17Q12_COPY_NUMBER_VARIATION_SYNDROME

TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3C TBC1D3B SLFN13 TBC1D3I TBC1D3G TBC1D3K

7.37e-10999110M46448
PathwayREACTOME_LRR_FLII_INTERACTING_PROTEIN_1_LRRFIP1_ACTIVATES_TYPE_I_IFN_PRODUCTION

IRF3 CREBBP EP300

2.58e-065913M27228
PathwayKEGG_MEDICUS_REFERENCE_TLR3_IRF3_SIGNALING_PATHWAY

IRF3 CREBBP EP300

2.13e-059913M47451
PathwayREACTOME_TRAF3_DEPENDENT_IRF_ACTIVATION_PATHWAY

IRF3 CREBBP EP300

1.12e-0415913M953
PathwayREACTOME_ZYGOTIC_GENOME_ACTIVATION_ZGA

TUT7 CREBBP EP300

1.66e-0417913M48025
Pubmed

TBC1D3, a hominoid oncoprotein, is encoded by a cluster of paralogues located on chromosome 17q12.

TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3I TBC1D3G TBC1D3K TBC1D3F

9.88e-28111271116863688
Pubmed

Identification of novel sequences in the repertoire of hypervariable TRE17 genes from immortalized nonmalignant and malignant human keratinocytes.

TBC1D3 TBC1D3D USP6 TBC1D3F

1.70e-10412748406013
Pubmed

The Tre2 (USP6) oncogene is a hominoid-specific gene.

TBC1D3 TBC1D3D TBC1D3C USP6

8.45e-105127412604796
Pubmed

Human TRE17 oncogene is generated from a family of homologous polymorphic sequences by single-base changes.

TBC1D3 TBC1D3D USP6 TBC1D3F

8.45e-10512748471161
Pubmed

DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.

TBC1D3E TBC1D3 TBC1D3H TBC1D3D TBC1D3B TBC1D3G TBC1D3F

1.08e-0874127716625196
Pubmed

Interferon regulatory factor 3 and CREB-binding protein/p300 are subunits of double-stranded RNA-activated transcription factor DRAF1.

IRF3 CREBBP EP300

4.76e-08312739488451
Pubmed

Transcriptional activity of interferon regulatory factor (IRF)-3 depends on multiple protein-protein interactions.

IRF3 CREBBP EP300

4.76e-083127312473110
Pubmed

Kaposi's sarcoma-associated herpesvirus-encoded vIRF-3 stimulates the transcriptional activity of cellular IRF-3 and IRF-7.

IRF3 CREBBP EP300

4.76e-083127314668346
Pubmed

Characterization of monoclonal antibodies raised against p300: both p300 and CBP are present in intracellular TBP complexes.

CREBBP TAF1 EP300

1.90e-07412738995708
Pubmed

HHV-8 encoded vIRF-1 represses the interferon antiviral response by blocking IRF-3 recruitment of the CBP/p300 coactivators.

IRF3 CREBBP EP300

1.90e-074127311314014
Pubmed

Virus infection induces the assembly of coordinately activated transcription factors on the IFN-beta enhancer in vivo.

IRF3 CREBBP EP300

1.90e-07412739660935
Pubmed

Interferon regulatory factor-7 synergizes with other transcription factors through multiple interactions with p300/CBP coactivators.

IRF3 CREBBP EP300

1.90e-074127312604599
Pubmed

MLL3/MLL4 are required for CBP/p300 binding on enhancers and super-enhancer formation in brown adipogenesis.

CREBBP KMT2D EP300

1.90e-074127328398509
Pubmed

Direct involvement of CREB-binding protein/p300 in sequence-specific DNA binding of virus-activated interferon regulatory factor-3 holocomplex.

IRF3 CREBBP EP300

1.90e-074127311940575
Pubmed

PRC17, a novel oncogene encoding a Rab GTPase-activating protein, is amplified in prostate cancer.

TBC1D3 TBC1D3D TBC1D3F

1.90e-074127312359748
Pubmed

Recruitment of activated IRF-3 and CBP/p300 to herpes simplex virus ICP0 nuclear foci: Potential role in blocking IFN-beta induction.

IRF3 CREBBP EP300

1.90e-074127317126870
Pubmed

New nomenclature for chromatin-modifying enzymes.

CREBBP KMT2D TAF1 TAF1L EP300

2.16e-0657127518022353
Pubmed

Immune evasion strategy involving propionylation by the KSHV interferon regulatory factor 1 (vIRF1).

IRF3 CREBBP EP300

5.60e-0610127337023208
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

IGSF8 FKRP DNAJC16 TUT7 EXT2 RXYLT1 LBR PIGU PDIA4 OLFML2A FAT1 POGLUT1 SGPL1 SELENOI DSEL USP48

8.29e-0612011271635696571
Pubmed

Screen identifies bromodomain protein ZMYND8 in chromatin recognition of transcription-associated DNA damage that promotes homologous recombination.

BAZ1B CREBBP TRIM66 TAF1 EP300

8.44e-0675127525593309
Pubmed

LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.

IGSF8 TCAF1 TBRG4 NUP85 FKRP MARS1 DNAJC16 TUT7 LARS1 EXT2 LBR PDIA4 MGAT1 EIF2B3

9.47e-069421271431073040
Pubmed

Mouse screen reveals multiple new genes underlying mouse and human hearing loss.

RPGRIP1L TTLL3 NUP85 OXR1 LARS1 BAZ1B FRYL GBA2 ATP8B2 BAP1 PDIA4 STK32A TRIM66 MYH14 GLO1 LEPROT

1.26e-0512421271630973865
Pubmed

Loss of p300 accelerates MDS-associated leukemogenesis.

CREBBP EP300

1.32e-052127227881875
Pubmed

CAPS1 and CAPS2 regulate stability and recruitment of insulin granules in mouse pancreatic beta cells.

CADPS CADPS2

1.32e-052127218177725
Pubmed

Molecular characterization of the histone acetyltransferase CREBBP/EP300 genes in myeloid neoplasia.

CREBBP EP300

1.32e-052127234845315
Pubmed

p300 plays a critical role in maintaining cardiac mitochondrial function and cell survival in postnatal hearts.

CREBBP EP300

1.32e-052127219729597
Pubmed

Crystal structure of IRF-3 in complex with CBP.

IRF3 CREBBP

1.32e-052127216154084
Pubmed

CREB-binding protein/P300 bromodomain inhibition reduces neutrophil accumulation and activates antitumor immunity in triple-negative breast cancer.

CREBBP EP300

1.32e-052127239287984
Pubmed

Phosphorylation of IRF-3 on Ser 339 generates a hyperactive form of IRF-3 through regulation of dimerization and CBP association.

IRF3 CREBBP

1.32e-052127218272581
Pubmed

Exon deletions of the EP300 and CREBBP genes in two children with Rubinstein-Taybi syndrome detected by aCGH.

CREBBP EP300

1.32e-052127220717166
Pubmed

The epigenetic regulators CBP and p300 facilitate leukemogenesis and represent therapeutic targets in acute myeloid leukemia.

CREBBP EP300

1.32e-052127225893291
Pubmed

Human T-lymphotropic virus type 1 p30(II) regulates gene transcription by binding CREB binding protein/p300.

CREBBP EP300

1.32e-052127211559821
Pubmed

CARM1 inhibition reduces histone acetyltransferase activity causing synthetic lethality in CREBBP/EP300-mutated lymphomas.

CREBBP EP300

1.32e-052127232576962
Pubmed

Syndromic features and mild cognitive impairment in mice with genetic reduction on p300 activity: Differential contribution of p300 and CBP to Rubinstein-Taybi syndrome etiology.

CREBBP EP300

1.32e-052127219822209
Pubmed

A specific CBP/p300-dependent gene expression programme drives the metabolic remodelling in late stages of spermatogenesis.

CREBBP EP300

1.32e-052127224522976
Pubmed

CBP is required for environmental enrichment-induced neurogenesis and cognitive enhancement.

CREBBP EP300

1.32e-052127221847097
Pubmed

The carbonic anhydrase domain of receptor tyrosine phosphatase beta is a functional ligand for the axonal cell recognition molecule contactin.

PTPRB CNTN1

1.32e-05212727628014
Pubmed

Taf1 knockout is lethal in embryonic male mice and heterozygous females show weight and movement disorders.

TAF1 TAF1L

1.32e-052127238804708
Pubmed

p300 or CBP is required for insulin-stimulated glucose uptake in skeletal muscle and adipocytes.

CREBBP EP300

1.32e-052127234813504
Pubmed

CAPS-1 and CAPS-2 are essential synaptic vesicle priming proteins.

CADPS CADPS2

1.32e-052127218022372
Pubmed

Rubinstein-Taybi Syndrome

CREBBP EP300

1.32e-052127220301699
Pubmed

Sustained expression of a neuron-specific isoform of the Taf1 gene in development stages and aging in mice.

TAF1 TAF1L

1.32e-052127222842574
Pubmed

Multi-ligand interactions with receptor-like protein tyrosine phosphatase beta: implications for intercellular signaling.

PTPRB CNTN1

1.32e-05212729584610
Pubmed

Potential biomarker of metformin action.

CREBBP EP300

1.32e-052127224639469
Pubmed

The histone acetyl transferases CBP and p300 regulate stress response pathways in synovial fibroblasts at transcriptional and functional levels.

CREBBP EP300

1.32e-052127237816914
Pubmed

Altered airway and cardiac responses in mice lacking G protein-coupled receptor kinase 3.

GRK2 GRK3

1.32e-052127210198406
Pubmed

Binding of p300/CBP co-activators by polyoma large T antigen.

CREBBP EP300

1.32e-052127211438528
Pubmed

Smad-dependent stimulation of type I collagen gene expression in human skin fibroblasts by TGF-beta involves functional cooperation with p300/CBP transcriptional coactivators.

CREBBP EP300

1.32e-052127210918613
Pubmed

Frameshift Mutations in the Mononucleotide Repeats of TAF1 and TAF1L Genes in Gastric and Colorectal Cancers with Regional Heterogeneity.

TAF1 TAF1L

1.32e-052127227571988
Pubmed

CAPS-1 requires its C2, PH, MHD1 and DCV domains for dense core vesicle exocytosis in mammalian CNS neurons.

CADPS CADPS2

1.32e-052127228883501
Pubmed

Striatal Cholinergic Dysregulation after Neonatal Decrease in X-Linked Dystonia Parkinsonism-Related TAF1 Isoforms.

TAF1 TAF1L

1.32e-052127234403156
Pubmed

Histone Acetyltransferases p300 and CBP Coordinate Distinct Chromatin Remodeling Programs in Vascular Smooth Muscle Plasticity.

CREBBP EP300

1.32e-052127235502657
Pubmed

p300 and cAMP response element-binding protein-binding protein in skeletal muscle homeostasis, contractile function, and survival.

CREBBP EP300

1.32e-052127231898871
Pubmed

G-protein coupled receptor kinase 2 and 3 expression in human detrusor cultured smooth muscle cells.

GRK2 GRK3

1.32e-052127211762794
Pubmed

Germline or inducible knockout of p300 or CBP in skeletal muscle does not alter insulin sensitivity.

CREBBP EP300

1.32e-052127230888860
Pubmed

Exploitation of EP300 and CREBBP Lysine Acetyltransferases by Cancer.

CREBBP EP300

1.32e-052127227881443
Pubmed

Spatiotemporal expression of histone acetyltransferases, p300 and CBP, in developing embryonic hearts.

CREBBP EP300

1.32e-052127219272189
Pubmed

Suppression of type I interferon production by porcine epidemic diarrhea virus and degradation of CREB-binding protein by nsp1.

IRF3 CREBBP

1.32e-052127226773386
Pubmed

Differential contribution of p300 and CBP to regulatory element acetylation in mESCs.

CREBBP EP300

1.32e-052127232690000
Pubmed

CBP/p300 antagonises EGFR-Ras-Erk signalling and suppresses increased Ras-Erk signalling-induced tumour formation in mice.

CREBBP EP300

1.32e-052127230953353
Pubmed

Disrupting the CH1 domain structure in the acetyltransferases CBP and p300 results in lean mice with increased metabolic control.

CREBBP EP300

1.32e-052127221803292
Pubmed

HIV-1 tat transactivator recruits p300 and CREB-binding protein histone acetyltransferases to the viral promoter.

CREBBP EP300

1.32e-05212729811832
Pubmed

Two independent regions of simian virus 40 T antigen increase CBP/p300 levels, alter patterns of cellular histone acetylation, and immortalize primary cells.

CREBBP EP300

1.32e-052127224089570
Pubmed

Activation of interferon regulatory factor 3 in response to DNA-damaging agents.

IRF3 CREBBP

1.32e-052127210521456
Pubmed

A ketogenic diet rescues hippocampal memory defects in a mouse model of Kabuki syndrome.

CREBBP KMT2D

1.32e-052127227999180
Pubmed

Genetic heterogeneity in Rubinstein-Taybi syndrome: mutations in both the CBP and EP300 genes cause disease.

CREBBP EP300

1.32e-052127215706485
Pubmed

AR coactivators, CBP/p300, are critical mediators of DNA repair in prostate cancer.

CREBBP EP300

1.32e-052127239266679
Pubmed

A boy with classical Rubinstein-Taybi syndrome but no detectable mutation in the CREBBP and EP300 genes.

CREBBP EP300

1.32e-052127222303793
Pubmed

Two distinct secretory vesicle-priming steps in adrenal chromaffin cells.

CADPS CADPS2

1.32e-052127220855507
Pubmed

Inhibition of histone acetyltransferase function radiosensitizes CREBBP/EP300 mutants via repression of homologous recombination, potentially targeting a gain of function.

CREBBP EP300

1.32e-052127234732714
Pubmed

Targeting histone acetylation dynamics and oncogenic transcription by catalytic P300/CBP inhibition.

CREBBP EP300

1.32e-052127234019788
Pubmed

Cloning of GRK2 cDNA from S49 murine lymphoma cells.

GRK2 GRK3

1.32e-05212728638670
Pubmed

Endogenous CCAAT/enhancer binding protein beta and p300 are both regulated by growth hormone to mediate transcriptional activation.

CREBBP EP300

1.32e-052127215860545
Pubmed

Further delineation of an entity caused by CREBBP and EP300 mutations but not resembling Rubinstein-Taybi syndrome.

CREBBP EP300

1.32e-052127229460469
Pubmed

CAPS facilitates filling of the rapidly releasable pool of large dense-core vesicles.

CADPS CADPS2

1.32e-052127218495893
Pubmed

Expression of p300 and CBP is associated with poor prognosis in small cell lung cancer.

CREBBP EP300

1.32e-052127224551300
Pubmed

Dissecting the roles of GRK2 and GRK3 in μ-opioid receptor internalization and β-arrestin2 recruitment using CRISPR/Cas9-edited HEK293 cells.

GRK2 GRK3

1.32e-052127233060647
Pubmed

Genome-wide CRISPR screens reveal synthetic lethal interaction between CREBBP and EP300 in diffuse large B-cell lymphoma.

CREBBP EP300

1.32e-052127233911074
Pubmed

The adenovirus 12 E1A proteins can bind directly to proteins of the p300 transcription co-activator family, including the CREB-binding protein CBP and p300.

CREBBP EP300

1.32e-05212729018065
Pubmed

Coactivators p300 and CBP maintain the identity of mouse embryonic stem cells by mediating long-range chromatin structure.

CREBBP EP300

1.32e-052127224648406
Pubmed

CBP and P300 regulate distinct gene networks required for human primary myoblast differentiation and muscle integrity.

CREBBP EP300

1.32e-052127230135524
Pubmed

Distribution of co-activators CBP and p300 during mouse oocyte and embryo development.

CREBBP EP300

1.32e-052127216596650
Pubmed

G protein--coupled receptor kinases.

GRK2 GRK3

1.32e-05212728035170
Pubmed

The p300 and CBP Transcriptional Coactivators Are Required for β-Cell and α-Cell Proliferation.

CREBBP EP300

1.32e-052127229217654
Pubmed

Evidence for opposing selective forces operating on human-specific duplicated TCAF genes in Neanderthals and humans.

TCAF2 TCAF1

1.32e-052127234433829
Pubmed

Differences in the interactions of oncogenic adenovirus 12 early region 1A and nononcogenic adenovirus 2 early region 1A with the cellular coactivators p300 and CBP.

CREBBP EP300

1.32e-052127210049825
Pubmed

Identification and characterization of photomedins: novel olfactomedin-domain-containing proteins with chondroitin sulphate-E-binding activity.

OLFML2B OLFML2A

1.32e-052127215836428
Pubmed

CBP/p300 acetyltransferase activity in hematologic malignancies.

CREBBP EP300

1.32e-052127227380996
Pubmed

CREBBP and p300 lysine acetyl transferases in the DNA damage response.

CREBBP EP300

1.32e-052127229170789
Pubmed

Crebbp haploinsufficiency in mice alters the bone marrow microenvironment, leading to loss of stem cells and excessive myelopoiesis.

CREBBP EP300

1.32e-052127221555743
Pubmed

CBP/p300 induction is required for retinoic acid sensitivity in human mammary cells.

CREBBP EP300

1.32e-052127212646247
Pubmed

Histone acetyltransferase activities of cAMP-regulated enhancer-binding protein and p300 in tissues of fetal, young, and old mice.

CREBBP EP300

1.32e-052127211867645
Pubmed

Expression of the nuclear coactivators CBP and p300 in developing craniofacial tissue.

CREBBP EP300

1.32e-052127211963968
Pubmed

Differential transcriptional activation by human T-cell leukemia virus type 1 Tax mutants is mediated by distinct interactions with CREB binding protein and p300.

CREBBP EP300

1.32e-05212729528808
Pubmed

Analysis of genetic stability at the EP300 and CREBBP loci in a panel of cancer cell lines.

CREBBP EP300

1.32e-052127212696060
Pubmed

Regulation of IRF-3-dependent innate immunity by the papain-like protease domain of the severe acute respiratory syndrome coronavirus.

IRF3 CREBBP

1.32e-052127217761676
Pubmed

TAFII250, Egr-1, and D-type cyclin expression in mice and neonatal rat cardiomyocytes treated with doxorubicin.

TAF1 TAF1L

1.32e-052127210070062
Pubmed

CBP Is Required for Establishing Adaptive Gene Programs in the Adult Mouse Brain.

CREBBP EP300

1.32e-052127236109165
Pubmed

Retinoids and retinoic acid receptors regulate growth arrest and apoptosis in human mammary epithelial cells and modulate expression of CBP/p300.

CREBBP EP300

1.32e-052127212242694
Pubmed

CBP/p300 Drives the Differentiation of Regulatory T Cells through Transcriptional and Non-Transcriptional Mechanisms.

CREBBP EP300

1.32e-052127231182547
InteractionOPA6 interactions

WWP2 FZR1 EP300

4.27e-0661223int:OPA6
InteractionPTPRB interactions

GHR PTPRB ADGRF5 CNTN1 FTSJ3

1.41e-05511225int:PTPRB
CytobandEnsembl 112 genes in cytogenetic band chr17q12

TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B SLFN13 TBC1D3I TBC1D3G TBC1D3K TBC1D3F

1.36e-1414912712chr17q12
Cytoband17q12

TBC1D3 TBC1D3H TBC1D3C TBC1D3B SLFN13 TBC1D3F

3.61e-0799127617q12
Cytoband7q35

TCAF2 TCAF1 PDIA4

4.88e-045512737q35
GeneFamilyZinc fingers ZZ-type|Lysine acetyltransferases

CREBBP TAF1 EP300

4.84e-0517773486
GeneFamilyFibronectin type III domain containing

IL20RB GHR PTPRB CNTN3 CNTN1

6.03e-04160775555
GeneFamilyMannosyl-glycoprotein N-acetylglucosaminyltransferases

MGAT4A MGAT1

6.32e-049772435
GeneFamilyDyneins, axonemal

DNAH3 DNAH14

2.34e-0317772536
GeneFamilyCadherin related

DCHS2 FAT1

2.34e-031777224
GeneFamilyZinc fingers ZZ-type|Lysine acetyltransferases

CREBBP EP300

2.62e-031877291
GeneFamilyAminoacyl tRNA synthetases, Class I

MARS1 LARS1

2.92e-0319772131
GeneFamilyGlycosyl transferases group 1 domain containing|Phosphatidylinositol glycan anchor biosynthesis

PIGU PIGZ

3.57e-0321772680
GeneFamilyCalcium voltage-gated channel subunits

CACNA1B CACNA1S

5.45e-0326772253
CoexpressionAtlasMesoderm Day 15_vs_Mesoderm Day 30-Confounder_removed-fold2.0_adjp0.05

TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3G TBC1D3K TBC1D3F

2.79e-09901249PCBC_ratio_MESO-15_vs_MESO-30_cfr-2X-p05
CoexpressionAtlasEndoderm Differentiated Cells-method_mRNA_vs_Endoderm Differentiated Cells-method_NA-Confounder_removed-fold2.0_adjp0.05

TBC1D3 ANGPT1 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3G TBC1D3K TBC1D3F

5.04e-0721312410PCBC_ratio_DE_from-mRNA_vs_DE_from-ESC_cfr-2X-p05
CoexpressionAtlasEndoderm Differentiated Cells-reprogram_OSKM-L_vs_Endoderm Differentiated Cells-reprogram_NA-Confounder_removed-fold2.0_adjp0.05

TBC1D3 ANGPT1 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3G TBC1D3K TBC1D3F

5.04e-0721312410PCBC_ratio_DE_from-OSKM-L_vs_DE_from-ESC_cfr-2X-p05
CoexpressionAtlasDE cord blood_vs_DE blastocyst-Confounder_removed-fold2.0_adjp0.05

TBC1D3 ANGPT1 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3G TBC1D3K TBC1D3F

1.61e-0624212410PCBC_ratio_DE cord blood_vs_DE blastocyst_cfr-2X-p05
CoexpressionAtlasMesoderm Day 5_vs_Endoderm Differentiated Cells-Confounder_removed-fold2.0_adjp0.05

TBC1D3 TTLL3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3G TBC1D3K TBC1D3F

1.88e-0532012410PCBC_ratio_MESO-5_vs_DE_cfr-2X-p05
CoexpressionAtlasMesoderm Day 5-reprogram_OSKM-L_vs_Mesoderm Day 5-reprogram_NA-Confounder_removed-fold2.0_adjp0.05

TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3G TBC1D3K TBC1D3F

4.12e-052811249PCBC_ratio_MESO-5_from-OSKM-L_vs_MESO-5_from-ESC_cfr-2X-p05
CoexpressionAtlasMesoderm Day 5-method_mRNA_vs_Mesoderm Day 5-method_NA-Confounder_removed-fold2.0_adjp0.05

TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3G TBC1D3K TBC1D3F

4.12e-052811249PCBC_ratio_MESO-5_from-mRNA_vs_MESO-5_from-ESC_cfr-2X-p05
ToppCellFrontal_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Sst|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

STK32B OOEP HPSE CHRNA2 STK32A OXTR

4.57e-071011276cf52c93f523c5f25bd45519a1444ce7bd1d8b577
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

STK32B OOEP HPSE CHRNA2 STK32A OXTR RASGRP2

5.93e-0717012778ab67e2b6e30fdf9e9a2c02e31d4df34e751a3ed
ToppCellLPS_only-Epithelial_alveolar|LPS_only / Treatment groups by lineage, cell group, cell type

NAPSA CYP4B1 OLFML2B PDIA4 MYH14 DSEL CADPS2

1.64e-061981277655df75b9692d815c7f6910275e1f684ac63bf62
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Crh_4930553C11Rik_|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

STK32B OOEP HPSE STK32A FAT1 RASGRP2

1.92e-0612912766bc85761dea1f97c19bb379a99e4daf85d53201e
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

STK32B OOEP CHRNA2 STK32A OXTR RASGRP2

6.92e-061611276dccb61d5e17a8f1c6d1fc146ee389f567659a0f0
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C_(NP)|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ANGPT1 ITGA8 PKD2L1 GHR FAT1 RASGRP2

9.12e-061691276bddb28a8b9afbe4a68f082e82caf96a6666fc674
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C_(NP)-Glut_NP_L5/6_FEZF2|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ANGPT1 ITGA8 PKD2L1 GHR FAT1 RASGRP2

9.12e-0616912765ce46bac8e767feec7ecdc61689de225c49bd3f7
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C_(NP)-Glut_NP_L5/6_FEZF2-Exc_L5-6_FEZF2_MYBPHL|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ANGPT1 ITGA8 PKD2L1 GHR FAT1 RASGRP2

1.11e-051751276bc6bd8c3ce956245ef4db91af9501649d5c09478
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L2-5_VIP_TOX2|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ANGPT1 ITGA8 HPSE CHRNA2 RIN2 DSEL

1.19e-05177127685e270b4a0b0da77ffe5987a099e827c02a4adf3
ToppCelldroplet-Liver-LIVER_NPC-30m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP4B1 ITGA8 HPSE PTPRB GYS1 ADGRF5

1.27e-051791276025d414ec88d5680d99c8173e70ee3bb0b694f74
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ANGPT1 ITGA8 HPSE CHRNA2 RIN2 DSEL

1.48e-05184127632473dbdb2de66391157c5814ef34e790806e4f2
ToppCelldroplet-Lung-3m-Endothelial-arterial_endothelial|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CYP4B1 STK32B STK32A PTPRB ADGRF5 CADPS2

1.57e-051861276b80aaeebc03a318052076d2f02c123f5ddc5e73a
ToppCelldroplet-Lung-3m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CYP4B1 STK32B STK32A PTPRB ADGRF5 CADPS2

1.57e-0518612768a8ed1502542d4895cba3fd5d534256206578716
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1|TCGA-Pancreas / Sample_Type by Project: Shred V9

UBR1 OXR1 CREBBP KLHL20 TAF1 EP300

1.57e-05186127603db813598b67b1e08f759758a1c2023396921fa
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ANGPT1 ITGA8 HPSE CHRNA2 RIN2 DSEL

1.67e-0518812766ee3f8f94ea7bdf652c9575fc65bff08070093a4
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ANGPT1 ITGA8 GHR OLFML2A CNTN3 CNTN1

1.72e-051891276203c80030df08ae112f9ae4043709f455d87ce89
ToppCellRA-10._Endothelium_II|RA / Chamber and Cluster_Paper

OXR1 ITGA8 PTPRB RIN2 ADGRF5 CADPS2

1.72e-051891276c81787a8c662db5d7814c583dd64562857629e81
ToppCellPCW_13-14|World / Celltypes from embryonic and fetal-stage human lung

ITGA8 OLFML2A GRK3 SLFN13 CNTN3 CNTN1

1.77e-05190127662a3ec1ae0829602b0569cc051210551644f1d46
ToppCellIPF-Epithelial-Club|World / Disease state, Lineage and Cell class

NAPSA CYP4B1 FAT1 MYH14 ADGRF5 CADPS2

1.83e-0519112763c88a6f1d74bb3b9173cd0ea3a63c6d9570e3954
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ANGPT1 ITGA8 HPSE CHRNA2 RIN2 DSEL

1.88e-0519212766a252e298f8a454623fa9c1c893a7a45a886d694
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro1_(4)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

ANGPT1 ITGA8 GHR CNTN3 CADPS2 CNTN1

1.94e-0519312769f69edc97b868d23998abc98928a2e89a885ef8a
ToppCellfacs-Lung-nan-3m-Endothelial-endothelial_cell_of_lung|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP4B1 GHR OLFML2A PTPRB RIN2 ADGRF5

1.99e-051941276f159ef8541d75a4e98468947f231bb463bec922c
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro1_(4)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

ANGPT1 ITGA8 GHR CNTN3 CADPS2 CNTN1

1.99e-05194127671d3c7448b1734de54187f902f65649f9283bd4c
ToppCellLV-09._Endothelium_I|World / Chamber and Cluster_Paper

MGAT4A FRYL PTPRB RIN2 ADGRF5 CADPS2

2.05e-05195127619e0a6c3eae1615aaa39767300acd937dfcb2a7f
ToppCellnucseq-Epithelial|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

NAPSA CYP4B1 DNAH14 MYH14 ADGRF5 CADPS2

2.05e-0519512769406866f99555198a9be311fbd65751b70f35446
ToppCellCOVID-19-Heart-EC_1|Heart / Disease (COVID-19 only), tissue and cell type

MGAT4A FRYL PTPRB RIN2 ADGRF5 CADPS2

2.05e-05195127650a193475db1bb1e05b8590225a553688c372c14
ToppCellLPS_IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

NAPSA CYP4B1 MYH14 ALOXE3 DSEL CADPS2

2.17e-051971276b94645d57efe8d9e032bffb8c89af1f425c6421e
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature1_(0)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

ANGPT1 ITGA8 GHR CNTN3 CADPS2 CNTN1

2.17e-05197127611a4c417f035e554431a8f03be13b5eefa3530c0
ToppCellLPS_IL1RA-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

NAPSA OLFML2B PDIA4 STK32A FAT1 CADPS2

2.24e-051981276285f729140b1df029c24f6ca1d2438470ac51794
ToppCellLPS_anti-TNF-Epithelial_alveolar|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

NAPSA CYP4B1 PDIA4 MYH14 DSEL CADPS2

2.24e-05198127653e9ed1b19cb26be58da0f37057caca0cdfaabeb
ToppCellLPS_anti-TNF-Epithelial_alveolar-AT_1-2_Progenitor-AT2_Progenitor|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

NAPSA CYP4B1 PDIA4 MYH14 DSEL CADPS2

2.24e-05198127682bcd44f8744e7e8477fbfd871a52f3d1a8b3adc
ToppCellLPS_IL1RA-Epithelial_alveolar|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

NAPSA CYP4B1 PDIA4 MYH14 DSEL CADPS2

2.30e-0519912765b140ac88ebc25ce397ae577e48f3e271faf46e7
ToppCellLPS_IL1RA_TNF-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

NAPSA CYP4B1 PDIA4 MYH14 DSEL CADPS2

2.30e-051991276121de4e02585de3a3010398387c523bacf8ce546
ToppCellNeuronal-Inhibitory-iA-iA_3(VIP)-VIP_2-TYR-L2-5|Neuronal / cells hierarchy compared to all cells using T-Statistic

ANGPT1 ITGA8 HPSE CHRNA2 RIN2 DSEL

2.37e-05200127604954fbe1e2264077228bb582c9a5897a70e6da2
ToppCellControl_saline-Epithelial_alveolar-AT_1-Differentiating_AT2|Control_saline / Treatment groups by lineage, cell group, cell type

NAPSA CYP4B1 CHRNA2 STK32A MYH14 GYS1

2.37e-052001276eac33be484dc443794e66e473f03e98406c2983e
ToppCellNeuronal-Inhibitory-iA-iA_3(VIP)-VIP_2-TYR|Neuronal / cells hierarchy compared to all cells using T-Statistic

ANGPT1 ITGA8 HPSE CHRNA2 RIN2 DSEL

2.37e-052001276bfdafb024a7b20d46837b2e6480dd4929253cd62
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Crhr2_Efemp1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

STK32B OOEP HPSE OXTR RASGRP2

4.43e-051361275e3a2425ba5ef538dbacab1479e682837ae42a888
ToppCellMild/Remission-B_naive-1|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)

TCAF1 TUT7 EEF1G GRK2 GRK3

5.63e-051431275bd3f5fbd4e9e4dc414682db5607494f3ce988deb
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Chrna2_Ptgdr|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

STK32B OOEP CHRNA2 OXTR RASGRP2

5.82e-05144127571107275767a0728541a3695715c44874b3e5efc
ToppCellControl-Epithelial_alveolar-AT_2-Differentiating_AT1|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CACNA1B CHRNA2 MYH14 SLFN13 FTSJ3

8.76e-0515712754766f7d545bf2d775390589460677519cb92f4d5
ToppCellfacs-Brain_Myeloid-Cerebellum-24m-Myeloid|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAPSA PDCD1 ANGPT1 B3GNT8 RASGRP2

9.02e-051581275f41ee21e5888359d817be1e3a902c132cb68e350
ToppCellTCGA-Bladder-Primary_Tumor-Urothelial_Carcinoma-Papillary_Muscle_Invasive_Urothelial_Carcinoma|TCGA-Bladder / Sample_Type by Project: Shred V9

TTLL3 TBC1D3L STK32A FER1L4 DEGS2

9.02e-051581275dc559503bab3ec1b9ea54ef2e896d1be33e5344c
ToppCellfacs-Brain_Myeloid-Cerebellum-24m-Myeloid-nan|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAPSA PDCD1 ANGPT1 B3GNT8 RASGRP2

9.02e-051581275d689feb7f612aef170da76fcf14abf2dd589082b
ToppCellfacs-Brain_Myeloid-Cerebellum-24m|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAPSA PDCD1 ANGPT1 B3GNT8 RASGRP2

9.02e-051581275829ff3df46f173f2ff1c435e9bce35425e603b42
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell_prolif|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TBC1D3L ITGA8 PTPRB CADPS ADGRF5

9.58e-051601275830e3ef8c9708d25872c3052a0b2682fa9372111
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Chrna2_Glra3|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SLC25A24 STK32B OOEP CHRNA2 RASGRP2

9.58e-0516012750bfdaf979e6f128cba2928ce16bca4d3deff8ac9
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Calb2_Pdlim5|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

OOEP HPSE STK32A OXTR RASGRP2

9.86e-051611275bf70be1de418615b5442ec684552551edaf1f072
ToppCellfacs-Heart-LA-18m-Lymphocytic-B_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAPSA CACNA1S GCM2 NOXRED1 GRK2

1.17e-0416712758ce8d93c79ac6a3f52252b4cec53378c362bfe0a
ToppCellfacs-Heart-LA-18m-Lymphocytic-B_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAPSA CACNA1S GCM2 NOXRED1 GRK2

1.17e-0416712758340f7075d00dccb304cfd4c9b5711ca6dbf7cce
ToppCellmild_COVID-19_(asymptomatic)-Plasmablast|World / disease group, cell group and cell class (v2)

NAPSA OOEP MYH14 CADPS FTSJ3

1.17e-041671275f26ae4de4804a3486502e3df37eabf3dfca688f5
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DPP10 STK32B LBR CNTN3 LEPROT

1.24e-0416912758f397cf4f9fd7c6fa88d01a95289ce2a6bc6938d
ToppCelldroplet-Liver-LIVER-30m-Myeloid-plasmacytoid_dendritic_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAPSA GCM2 HPSE B3GNT8 TRAF4

1.34e-04172127524ecfda5e43e28f190089770cd2eae5bf2ed292b
ToppCelldroplet-Liver-LIVER-30m-Myeloid-plasmacytoid_dendritic_cells|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAPSA GCM2 HPSE B3GNT8 TRAF4

1.34e-041721275db5a31cafce4346fe459d7f35210823fd7004439
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L4-5_RORB_LCN15|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DPP10 DNAH14 GHR CNTN3 CADPS2

1.42e-0417412752947e5906b172d149412fa4e77476fce4ea695d2
ToppCellfacs-Trachea-24m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CACNA1B GCM2 STK32B OOEP SBK2

1.46e-041751275f1394aacc8a94ca555dd19aaed5a18da99c6bf40
ToppCellfacs-Trachea-24m-Mesenchymal-myofibroblast|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CACNA1B GCM2 STK32B OOEP SBK2

1.46e-0417512757bf1194d93fbe2dbf9d953e0a32b2a6d88251ed1
ToppCellfacs-Trachea-24m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l34|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

WWP2 STK32B MGAT4A OOEP CNTN1

1.50e-04176127577c3da2eaa072a6baefb5087fd07ec18c5e271cd
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ITGA8 OLFML2A PTPRB RIN2 ADGRF5

1.50e-04176127564e426f5e84884ce2c29acf6f4b958962a63927f
ToppCellfacs-Trachea-24m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l6-17|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CACNA1B TTLL3 ITGA8 STK32A SBK2

1.54e-0417712758abdf1d970b2f15e17e185f3e612dd5065c88757
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-enteroendocrine_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OOEP STK32A GRK3 CADPS ADGRF5

1.58e-04178127530ca37f70d267cc9b40ca3e211f16d30360c3e6b
ToppCellCOVID-19-Epithelial_cells-AT1|COVID-19 / group, cell type (main and fine annotations)

NAPSA CYP4B1 STK32A MYH14 ADGRF5

1.62e-041791275a0b33bd69ffdfd5d38d80207fb40058a490aa19e
ToppCellLPS_only-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NAPSA OLFML2B STK32A MYH14 CADPS2

1.62e-041791275fd2cbee532e7b44113410dca82aec7db1a7fb69f
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5-Exc_L4-5_RORB_HNRNPA1P46|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DPP10 PKD2L1 GHR CNTN3 CADPS2

1.62e-04179127553e700494d251ec5649b2dea5fc7d5aeeeed572b
ToppCellfacs-Marrow-T_cells-18m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAPSA CACNA1S CYP4B1 PTPRB ADGRF5

1.66e-041801275243622eee35d38748e945677ff115616e763e3b4
ToppCellfacs-Marrow-T_cells-18m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAPSA CACNA1S CYP4B1 PTPRB ADGRF5

1.66e-0418012753a8d9a71efe113d1df3933902a625c0a56812074
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L2-5_VIP_TOX2|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ITGA8 HPSE CHRNA2 RIN2 DSEL

1.70e-04181127535bcdcd2651149692e5b150e887c0f450c81d2d4
ToppCelldroplet-Lung-3m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

STK32B PTPRB ADGRF5 DEGS2 CADPS2

1.70e-0418112752c44c41b4e8a75ebdbaeb0c6cc5a03f17c44758c
ToppCelldroplet-Liver-nan-3m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP4B1 ITGA8 PTPRB ADGRF5 CADPS2

1.70e-041811275fcc94f04dae98b817ec06b282d2e887804d37ae5
ToppCell10x5'-bone_marrow-Myeloid_Mac-Macrophage|bone_marrow / Manually curated celltypes from each tissue

OLFML2B PKD2L1 RIN2 LEPROT TAF1

1.70e-041811275d2aa5b53162fb5c4cbbedbd2cb4b2b614e8c4afa
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L2-5_VIP_TOX2|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ITGA8 HPSE CHRNA2 RIN2 DSEL

1.70e-041811275154d5e586cab25155c6d06dfe6ae01203b88e0fb
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L2-5_VIP_TOX2|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ANGPT1 ITGA8 CHRNA2 RIN2 DSEL

1.75e-0418212753d7a8d2ee2137b098248597058974ef5ae09c19e
ToppCellCOVID-19-Epithelial_cells-ECM-high_epithelial|COVID-19 / group, cell type (main and fine annotations)

NAPSA CYP4B1 STK32A MYH14 ADGRF5

1.79e-041831275dc1d380bf7564f290256cb7108063d1bd2da732b
ToppCellCOVID-19-lung-Epithelial|COVID-19 / Disease (COVID-19 only), tissue and cell type

KCTD7 NAPSA CYP4B1 EEF1G LEPROT

1.79e-0418312753a5d00006a195b5a5c27e7ace615e5de73145e97
ToppCellCOVID-19-lung-AT1|lung / Disease (COVID-19 only), tissue and cell type

NAPSA CYP4B1 DNAH14 STK32A MYH14

1.79e-041831275942530449e9c6583705eeb8f6f12621daea57252
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L2-5_VIP_TOX2|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ITGA8 HPSE CHRNA2 RIN2 DSEL

1.89e-041851275caf4f57f2db9ff72a652c8573e16e7ab180ffc05
ToppCellCOVID-19-Epithelial_cells-Airway_club|COVID-19 / group, cell type (main and fine annotations)

DPP10 STK32A MYH14 ADGRF5 CADPS2

1.89e-041851275cfe6fd73d817e173fe803bc1683c291d9bcb8608
ToppCell(2)_5-FU-(2)_LEPR+_perivascular_cells_and_VE-Cad+_vascular_cells_(mixed)|(2)_5-FU / Stress and Cell class

ANGPT1 OLFML2B PDIA4 GHR RMND1

1.98e-0418712756bbf0f7fe203274dae8d582652f35cd3187c0065
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ANGPT1 HPSE CHRNA2 RIN2 DSEL

2.03e-041881275c66fccdfe68760b8c3efca77e3c25966dc9a8a5f
ToppCellCOVID-19-Epithelial_cells|COVID-19 / group, cell type (main and fine annotations)

NAPSA CYP4B1 STK32A MYH14 ADGRF5

2.03e-041881275c9cdee6f8d42ee69f5fb335f25084603c511bd29
ToppCell10x3'2.3-week_14-16-Mesenchymal_myocytic-stroma-muscle_stem_cell|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

OLFML2B ITGA8 GHR OLFML2A FAT1

2.03e-041881275de6f4889e0c5f39fbbaefd85526f645c6afa09d5
ToppCellRA-10._Endothelium_II|World / Chamber and Cluster_Paper

OXR1 ITGA8 PPEF1 PTPRB CADPS2

2.08e-04189127575c248b9de5e2fb7a0baa8cdbab516e575cc4394
ToppCellIPF-Epithelial-Club|IPF / Disease state, Lineage and Cell class

NAPSA CYP4B1 MYH14 ADGRF5 CADPS2

2.08e-041891275f3fcef008ef252b29ac6d567fef27f9acf9cd70f
ToppCellControl-Endothelial-VE_Capillary_B|Endothelial / Disease state, Lineage and Cell class

FAT1 PTPRB RIN2 ADGRF5 CADPS2

2.14e-0419012757f3f419fffe02934b6f27b697f7a6401072491ed
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DCHS2 ANGPT1 ITGA8 GHR CNTN1

2.14e-0419012752306aa9dbeaef3be8484a5b236605de23cd75d4c
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DCHS2 ANGPT1 ITGA8 GHR CNTN1

2.14e-0419012751f83f7f24288a3b9ab33c2e113e845dba96adc8a
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DCHS2 ANGPT1 ITGA8 GHR CNTN1

2.19e-041911275a58c75e9580139fb370b498d95660f10f3a2a27b
ToppCellCOVID-19-lung-AT2|lung / Disease (COVID-19 only), tissue and cell type

NAPSA DNAH14 STK32A MYH14 ADGRF5

2.19e-041911275276455a64c2c3503d5048615762eb2ee37f0ac70
ToppCellEpithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|World / Lineage, Cell type, age group and donor

CYP4B1 DNAH14 MYH14 ADGRF5 CADPS2

2.19e-041911275d3733c8c4bda70c4390e5601fdda6188a64be944
ToppCell10x3'2.3-week_12-13-Mesenchymal_osteo-stroma-osteoblast_precursor|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

OLFML2B ITGA8 GHR FAT1 CNTN1

2.19e-04191127598b907f8fa024cf32e462323b782c5a371327bbd
ToppCellChildren_(3_yrs)-Epithelial|Children_(3_yrs) / Lineage, Cell type, age group and donor

NAPSA DNAH14 MYH14 ADGRF5 CADPS2

2.19e-041911275e432c6e1ae82dddf84314ce73d2b7a991630d905
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DCHS2 ANGPT1 ITGA8 GHR CNTN1

2.24e-0419212759093a9e94a25682d109a7f6edc256a25a61103a0
ToppCellEpithelial|World / Lineage, Cell type, age group and donor

NAPSA DNAH14 MYH14 ADGRF5 CADPS2

2.24e-041921275499e8893afea5e6d3371e0bd018f7e86a524d669
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DCHS2 ANGPT1 ITGA8 GHR CNTN1

2.24e-0419212759ed5d49621ec1aa01716dc369bba1450b5f015f5
ToppCellAdult-Epithelial|Adult / Lineage, Cell type, age group and donor

NAPSA DNAH14 MYH14 ADGRF5 CADPS2

2.24e-041921275efb962a5fd3b9bdfd8cf8d13c435e29c8271713e
ToppCellRV-10._Endothelium_II|RV / Chamber and Cluster_Paper

OXR1 PTPRB RIN2 ADGRF5 CADPS2

2.30e-04193127501c2df9206f1527c578e808978e58196c35e72f5
ToppCellRV-10._Endothelium_II|World / Chamber and Cluster_Paper

OXR1 PTPRB RIN2 ADGRF5 CADPS2

2.30e-0419312752531266bc57339d4e2b22a88817008e32b8c1598
ToppCellMesenchymal-matrix_fibroblast_1_cell|World / Lineage, Cell type, age group and donor

ANGPT1 ITGA8 GHR OLFML2A CNTN3

2.30e-041931275acad568621ed677031797b8c2e34dafea798d681
ToppCellwk_20-22-Mesenchymal-Myofibro_&_SMC-Vascular_SMC_1|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

ANGPT1 OLFML2B FAT1 CADPS ADGRF5

2.30e-041931275ba6eb29478d16589172f48f9992e5116328c81d6
ToppCellRV-09._Endothelium_I|World / Chamber and Cluster_Paper

FRYL PTPRB RIN2 ADGRF5 CADPS2

2.30e-041931275e3fa47e2c7cd8a5b69186711c57751f2296de8ae
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ANGPT1 ITGA8 OLFML2A CNTN3 CNTN1

2.35e-041941275011e14d9ed1393275f892060e7708ffadcd0767f
DiseaseRUBINSTEIN-TAYBI SYNDROME 1

CREBBP EP300

1.53e-0521162180849
DiseaseRubinstein-Taybi syndrome due to CREBBP mutations

CREBBP EP300

1.53e-0521162cv:C4551859
DiseaseInfantile liver failure

MARS1 LARS1

1.53e-0521162cv:C5681094
DiseaseMenke-Hennekam syndrome

CREBBP EP300

1.53e-0521162cv:C5681632
DiseaseRubinstein-Taybi syndrome (implicated_via_orthology)

CREBBP EP300

1.53e-0521162DOID:1933 (implicated_via_orthology)
DiseaseRubinstein-Taybi syndrome

CREBBP EP300

1.53e-0521162cv:C0035934
DiseaseRUBINSTEIN-TAYBI SYNDROME 1

CREBBP EP300

1.53e-0521162C4551859
DiseaseRubinstein-Taybi syndrome (is_implicated_in)

CREBBP EP300

1.53e-0521162DOID:1933 (is_implicated_in)
DiseaseRubinstein-Taybi Syndrome

CREBBP EP300

1.53e-0521162C0035934
DiseaseSquamous cell carcinoma of esophagus

CREBBP FAT1 KMT2D GLO1 EP300

3.76e-05951165C0279626
DiseaseNeuronal Ceroid-Lipofuscinoses

KCTD7 CLN3

2.27e-0461162C0027877
DiseaseBladder Neoplasm

CYP4B1 CREBBP BAP1 KMT2D EP300

2.35e-041401165C0005695
DiseaseMalignant neoplasm of urinary bladder

CYP4B1 CREBBP BAP1 KMT2D EP300

2.43e-041411165C0005684
Diseaseglycosyl-N-behenoyl-sphingadienine (d18:2/22:0) measurement

GBA2 SGPL1

3.18e-0471162EFO_0800520
Diseasesystemic lupus erythematosus (implicated_via_orthology)

PDCD1 LBR EP300

6.51e-04431163DOID:9074 (implicated_via_orthology)
DiseaseSmall cell carcinoma of lung

CREBBP TAF1L EP300

1.27e-03541163C0149925
DiseaseMetastatic melanoma

STK32B STK32A TAF1

1.27e-03541163C0278883
DiseaseDiffuse Large B-Cell Lymphoma

CREBBP KMT2D EP300

1.34e-03551163C0079744
DiseaseMUSCULAR DYSTROPHY, LIMB-GIRDLE, TYPE 2K

FKRP RXYLT1

1.35e-03141162C1836373
Diseasealpha-Dystroglycanopathies

FKRP RXYLT1

1.35e-03141162C2936406
DiseaseFukuyama Type Congenital Muscular Dystrophy

FKRP RXYLT1

1.35e-03141162C0410174
Diseasethalamus volume change measurement

OOEP FAT1

1.35e-03141162EFO_0021496
DiseaseMuscle eye brain disease

FKRP RXYLT1

1.35e-03141162C0457133
DiseaseMuscular Dystrophy-Dystroglycanopathy (Congenital with Brain and Eye Anomalies) Type A, 1

FKRP RXYLT1

1.35e-03141162C4284790
DiseaseWalker-Warburg congenital muscular dystrophy

FKRP RXYLT1

1.56e-03151162C0265221
DiseaseLymphoma, Follicular, Grade 2

CREBBP KMT2D

1.56e-03151162C1956132
DiseaseLymphoma, Follicular, Grade 3

CREBBP KMT2D

1.56e-03151162C1956131
DiseaseLymphoma, Follicular, Grade 1

CREBBP KMT2D

1.56e-03151162C1956130
Diseasemyelodysplastic syndrome (implicated_via_orthology)

CREBBP BAP1

1.56e-03151162DOID:0050908 (implicated_via_orthology)
DiseaseLymphoma, Large-Cell, Follicular

CREBBP KMT2D

1.56e-03151162C0079745
DiseaseLymphoma, Small Cleaved-Cell, Follicular

CREBBP KMT2D

1.56e-03151162C0079765
DiseaseLymphoma, Mixed-Cell, Follicular

CREBBP KMT2D

1.56e-03151162C0079758
DiseaseSeizures

CACNA1B OXR1 FKRP PIGU CLPB

1.74e-032181165C0036572
DiseaseT-Cell Lymphoma

KMT2D EP300

1.77e-03161162C0079772
DiseaseGlobal developmental delay

CACNA1B OXR1 PIGU TAF1

1.91e-031331164C0557874
Diseasemacrophage inflammatory protein 1b measurement

TBC1D3 ANGPT1 TBC1D3B TBC1D3F

2.07e-031361164EFO_0008219
Diseasebreast carcinoma (is_marker_for)

SRD5A1 KMT2D EP300

2.26e-03661163DOID:3459 (is_marker_for)
Diseasetoxic shock syndrome (is_marker_for)

PDCD1 GRK2

2.51e-03191162DOID:14115 (is_marker_for)
Diseaseskin pigmentation

TTLL3 CADPS2 USP48

2.57e-03691163EFO_0003784
DiseaseCCL4 measurement

TBC1D3 TBC1D3F

2.78e-03201162EFO_0004751
DiseaseLymphoma, Follicular

CREBBP KMT2D

2.78e-03201162C0024301
Diseasebipolar disorder, body mass index

RPGRIP1L CLN3 RIN2

2.90e-03721163EFO_0004340, MONDO_0004985
Diseasemelanoma

PDCD1 HPSE BAP1 GLO1 EP300

3.03e-032481165C0025202
DiseaseProstatic Neoplasms

SRD5A1 CREBBP BAP1 GHR KMT2D MYH14 ALOXE3 TAF1L

3.05e-036161168C0033578
DiseaseMalignant neoplasm of prostate

SRD5A1 CREBBP BAP1 GHR KMT2D MYH14 ALOXE3 TAF1L

3.05e-036161168C0376358
Diseasegestational age, birth measurement

OXR1 OLFML2B

3.06e-03211162EFO_0005112, EFO_0006921
Diseasecardiovascular system disease (is_implicated_in)

UBR1 GYS1

3.06e-03211162DOID:1287 (is_implicated_in)
DiseaseHereditary Paraganglioma-Pheochromocytoma Syndrome

BAP1 KMT2D

3.67e-03231162C1708353
DiseaseAutistic Disorder

GHR OXTR GLO1 CNTN3 CADPS2

3.77e-032611165C0004352

Protein segments in the cluster

PeptideGeneStartEntry
LYTVLGPWFFGEIID

TMEM62

491

Q0P6H9
LPYFEGDFWPNVLEE

EP300

1501

Q09472
FYLFPNRLEWRGEGE

GRK3

581

P35626
KPFNELWDYEVVEAF

C4orf33

51

Q8N1A6
RYWLFSDEVPGLFIE

BAZ1B

911

Q9UIG0
ELPYFEGDFWPNVLE

CREBBP

1536

Q92793
WIPDIVLYNNADGEF

CHRNA2

141

Q15822
GPVYGFIFLFKWIEE

BAP1

41

Q92560
PSGEYWLGNEFIFAI

ANGPT1

351

Q15389
EFERILQFYWVTGFP

CC2D2B

1366

Q6DHV5
PGAYFRDLWNILDFI

CACNA1B

1211

Q00975
IIFNGIADWLYEEEL

DPP10

221

Q8N608
FYLFPNRLEWRGEGE

GRK2

581

P25098
QVYLPWDEAVDSAFF

ATP8B2

326

P98198
LAFGDLVWVPFIYSF

LBR

456

Q14739
DYIWDFVLYPNGALE

AOC2

466

O75106
FHVGDEWLEFFYPQL

POGLUT1

291

Q8NBL1
LGWFSPGQVFVLDEY

CADPS

701

Q9ULU8
RFANLTPEEFVGDYW

FAT1

3646

Q14517
DFFWAITPIAGDYIL

MGAT4A

416

Q9UM21
ALEDYGVYWPLFVLI

LEPROT

26

O15243
PAGDWEQYRILLFND

PTPRB

401

P23467
EFLLIAFTEYPEWAL

OR9Q1

11

Q8NGQ5
SFGPWEAVADVYDLL

KCTD7

231

Q96MP8
GDIPNFGTVEYWFRL

RPGRIP1L

721

Q68CZ1
YWISAFPAEFDLNPE

RASGRP2

81

Q7LDG7
ELLYRTDFFPGLGWL

MGAT1

256

P26572
WQLLEQYPAAFEFSE

MTMR10

471

Q9NXD2
GNIFLADYWILAEAP

ALOXE3

321

Q9BYJ1
EFNHFEDWLNVFPLY

FER1L4

1181

A9Z1Z3
EEYQREGIPWTFLDF

MYH14

516

Q7Z406
VPVFSVDYGELDFQW

PDCD1

216

Q15116
LAFIQDPDGYWIEIL

GLO1

161

Q04760
LWQLGVDYFDYCPEL

NUP85

416

Q9BW27
FDWFFGYDEVQGLLL

CSKMT

51

A8MUP2
DFPDWREDVLSGFVY

FRYL

606

O94915
EWLEYLLEFAQDAAP

DNAJC16

666

Q9Y2G8
IDEVWPSLFLGDAYA

DUSP13

46

Q9UII6
QLLWDITFRFYGPDL

OXTR

96

P30559
DLTPNIGLFWYFFAE

PIGU

266

Q9H490
ENFDPLPDYWLSLLF

HPSE

396

Q9Y251
EVGWPFSARDEFLLY

ITGA8

841

P53708
LEDLGPQFEFLVAYW

IL20RB

156

Q6UXL0
YNFRVFAWIPEDGFL

DCHS2

1156

Q6V1P9
VFYLEAWLADELFGP

OOEP

51

A6NGQ2
FFIQWSPEIYAEDTG

OXR1

606

Q8N573
DFREWFEFSPYEVGL

PLA2G4E

526

Q3MJ16
APELQDDFYLNLVDW

FZR1

181

Q9UM11
PYEQSEILGYAELWF

DYRK4

51

Q9NR20
IWYPLNLLERVGFEE

EIF2B3

36

Q9NR50
NFEWFLYRPEAPDTA

IGSF8

61

Q969P0
IEVFDPDANTWRLYG

KLHL20

571

Q9Y2M5
GWNIPYEFNESDLRI

DNAH3

3691

Q8TD57
FNELYFLADGGTVWL

GBA2

481

Q9HCG7
EDFYFPWLLIIIFGI

GHR

261

P10912
GYFGDPWNVFDFLIV

CACNA1S

1176

Q13698
DDLSYRWLLNEFPVF

CNTN1

166

Q12860
VLWDFVFEDSLGPYA

DEGS2

296

Q6QHC5
LGWFSPGQVFVLDEY

CADPS2

666

Q86UW7
FLPEEEWNIFLYSGI

DNAH14

2841

Q0VDD8
SLGDGIFWIQERFYE

MBLAC2

11

Q68D91
AVVGVEAWYEPFLFN

SELENOI

201

Q9C0D9
NGWYDEEHPLVFLFL

CLPB

366

Q9H078
APDVYDFFLQWIGRG

CYP4B1

111

P13584
ELAFPLSPDWQVDYE

EEF1G

381

P26641
IIPWDYDVDLGIYLE

FKRP

356

Q9H9S5
VPWYDREANDAVLFG

GYS1

141

P13807
YSDLLLWDFLDVPFN

B3GNT8

206

Q7Z7M8
PLAEADPFYEDFLIW

SBK2

266

P0C263
FIIYDSPWINDVDVF

RXYLT1

226

Q9Y2B1
EKDCPGVLWIFLDYF

SLFN13

691

Q68D06
WFYGPESQLVFLDKF

DSEL

336

Q8IZU8
DPLLDIIFTWYFNGA

CNTN3

526

Q9P232
AAGFLIVDVPFYEWL

TBRG4

591

Q969Z0
IDFAVDESGLWVIYP

OLFML2A

521

Q68BL7
EFYAWLPIGTIVDNE

PPEF1

266

O14829
LVPGEEWEFEVTAFY

IRF3

196

Q14653
QFEYGVPEEDRIWLY

NOXRED1

11

Q6NXP6
WVEKYFGPDFLEQIV

NT5M

146

Q9NPB1
ETYLQLQEAFGWEPF

TCAF1

831

Q9Y4C2
ETYLQLQEAFGWEPF

TCAF2

831

A6NFQ2
DQLKQEFEFWYPVDL

LARS1

656

Q9P2J5
IFPIDNEDLVYGRWE

TAF1L

486

Q8IZX4
SIFPIDNEDLVYGRW

TAF1

466

P21675
ELALFDQFREWPDGY

GCM2

31

O75603
RYTFNEDEGELPEWF

FTSJ3

691

Q8IY81
ITPDFYWDRENLEGL

RMND1

371

Q9NWS8
VNDADIILVEFYAPW

PDIA4

191

P13667
PFLVNLWYSFQDEED

STK32A

81

Q8WU08
LFLLYLPEEDAFWAL

TBC1D3L

196

B9A6J9
YIEAREGWPLIDYVF

MROH2B

386

Q7Z745
EGWPLIDYVFSQFAT

MROH2B

391

Q7Z745
DFAVDENGLWLIYPA

OLFML2B

621

Q68BL8
LLIVWGYEFVFQPES

SGPL1

51

O95470
VFPYFDLWGNVVIDK

ADGRF5

871

Q8IZF2
ADVWFGFLPSIYLVF

CLN3

361

Q13286
YEFVGLEFLPHLQTW

CHST4

291

Q8NCG5
LFLLYLPEEDAFWAL

TBC1D3B

196

A6NDS4
LFLLYLPEEDAFWAL

TBC1D3H

196

P0C7X1
PEEYSLFLFVDETWQ

RIN2

831

Q8WYP3
DGFNEVAPLEWLRYF

WWP2

726

O00308
LFLLYLPEEDAFWAL

TBC1D3F

196

A6NER0
AVYFSEEEWQLLGPL

ZNF75CP

211

Q92670
SDELQFGYEVWREFP

EXT2

546

Q93063
LVGAVLAFPSLYWDD

UBR1

1406

Q8IWV7
LAFPSLYWDDPVDLQ

UBR1

1411

Q8IWV7
LFLLYLPEEDAFWAL

TBC1D3E

196

A0A087X179
YIRVLPGAFDNLLEW

TRAF4

366

Q9BUZ4
DFVFGEDFQPWLIEI

TTLL3

456

Q9Y4R7
EDILGVQAARPWEFY

PIGZ

71

Q86VD9
DFWDFAQGPLLDSLY

PKD2L1

156

Q9P0L9
YADDWVTDPRFLIGF

SRD5A1

141

P18405
EDLYEGFDAFWPSLE

SLC9C2

976

Q5TAH2
PFLVNLWYSFQDEED

STK32B

81

Q9NY57
LFLLYLPEEDAFWAL

TBC1D3D

196

A0A087WVF3
KPEIFVDGWNIYFFD

TUT7

1201

Q5VYS8
LEVFFEGWLKEIYPE

TRIM66

1136

O15016
LFLLYLPEEDAFWAL

TBC1D3G

196

Q6DHY5
LFLLYLPEEDAFWAL

TBC1D3

196

Q8IZP1
AGAEPYEFVSLEWLQ

USP48

481

Q86UV5
EQFPLFEAFLLAAWE

ZFYVE26

1361

Q68DK2
PLEGFEDKVFYVWFD

MARS1

506

P56192
EWRDYFLFNPVTDIE

SLC25A24

146

Q6NUK1
LFLLYLPEEDAFWAL

TBC1D3K

196

A0A087X1G2
FLLYLPEEDAFWALV

USP6

196

P35125
GPEFYFENISLSWEE

TEX13B

31

Q9BXU2
LFLLYLPEEDAFWAL

TBC1D3I

196

A0A087WXS9
LFLLYLPEEDAFWAL

TBC1D3C

196

Q6IPX1
EPQYFRFEGVWLTET

KMT2D

1581

O14686
IFGEALWEPSLVFAF

NAPSA

166

O96009