Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcessregulation of anatomical structure morphogenesis

PLXNA3 NPPB PDE3B SARM1 GAS2 ADGRB2 SEMA3G ITGA7 DCX KLF2 THBS2 CELSR1 MKLN1 LRP6 NOS3 NOTCH1 PLXNB3 ARHGAP33 BRWD1

5.32e-06109011119GO:0022603
GeneOntologyBiologicalProcesscell morphogenesis

PLXNA3 SARM1 GAS2 SOX17 LAMA3 SEMA3G ITGA7 DCX ITPR1 KLF2 FRY MKLN1 KIAA1755 LRP6 NOTCH1 PLXNB3 ARHGAP33 NOTCH3 BRWD1

1.92e-05119411119GO:0000902
DomainEGF

ZAN THBS2 CELSR1 SCUBE3 LRP6 NOTCH1 NOTCH3

9.62e-061261107PF00008
DomainEGF

ZAN LAMA3 THBS2 CELSR1 SCUBE3 LRP6 NOTCH1 NOTCH3

7.58e-052351108SM00181
DomainDUF3454

NOTCH1 NOTCH3

1.03e-0431102PF11936
DomainDUF3454_notch

NOTCH1 NOTCH3

1.03e-0431102IPR024600
DomainDUF3454

NOTCH1 NOTCH3

1.03e-0431102SM01334
DomainEGF-like_dom

ZAN LAMA3 THBS2 CELSR1 SCUBE3 LRP6 NOTCH1 NOTCH3

1.13e-042491108IPR000742
DomainEGF_1

ZAN LAMA3 THBS2 CELSR1 SCUBE3 LRP6 NOTCH1 NOTCH3

1.34e-042551108PS00022
DomainEGF-like_CS

ZAN LAMA3 THBS2 CELSR1 SCUBE3 LRP6 NOTCH1 NOTCH3

1.57e-042611108IPR013032
DomainEGF_2

ZAN LAMA3 THBS2 CELSR1 SCUBE3 LRP6 NOTCH1 NOTCH3

1.74e-042651108PS01186
DomainNotch

NOTCH1 NOTCH3

2.05e-0441102IPR008297
DomainNODP

NOTCH1 NOTCH3

2.05e-0441102PF07684
DomainNotch_NODP_dom

NOTCH1 NOTCH3

2.05e-0441102IPR011656
DomainNotch_NOD_dom

NOTCH1 NOTCH3

2.05e-0441102IPR010660
DomainNOD

NOTCH1 NOTCH3

2.05e-0441102PF06816
DomainNOD

NOTCH1 NOTCH3

2.05e-0441102SM01338
DomainNODP

NOTCH1 NOTCH3

2.05e-0441102SM01339
DomainConA-like_dom

ZAN LAMA3 TRIM27 THBS2 CELSR1 TRIM36 ALK

3.17e-042191107IPR013320
DomainLNR

NOTCH1 NOTCH3

3.40e-0451102PS50258
DomainEGF_3

ZAN THBS2 CELSR1 SCUBE3 LRP6 NOTCH1 NOTCH3

4.84e-042351107PS50026
DomainTSP_1

ADAMTS4 ADGRB2 THBS2 SPON2

5.19e-04631104PF00090
DomainTSP1

ADAMTS4 ADGRB2 THBS2 SPON2

5.85e-04651104SM00209
DomainTSP1_rpt

ADAMTS4 ADGRB2 THBS2 SPON2

5.85e-04651104IPR000884
DomainTSP1

ADAMTS4 ADGRB2 THBS2 SPON2

5.85e-04651104PS50092
DomainNotch_dom

NOTCH1 NOTCH3

7.08e-0471102IPR000800
DomainNotch

NOTCH1 NOTCH3

7.08e-0471102PF00066
DomainNL

NOTCH1 NOTCH3

7.08e-0471102SM00004
DomainEGF_CA

THBS2 CELSR1 SCUBE3 NOTCH1 NOTCH3

7.76e-041221105SM00179
DomainSemap_dom

PLXNA3 SEMA3G PLXNB3

7.92e-04311103IPR001627
DomainSEMA

PLXNA3 SEMA3G PLXNB3

7.92e-04311103PS51004
DomainSema

PLXNA3 SEMA3G PLXNB3

7.92e-04311103SM00630
DomainSema

PLXNA3 SEMA3G PLXNB3

7.92e-04311103PF01403
DomainEGF-like_Ca-bd_dom

THBS2 CELSR1 SCUBE3 NOTCH1 NOTCH3

8.35e-041241105IPR001881
DomainPlexin_repeat

PLXNA3 SEMA3G PLXNB3

8.71e-04321103IPR002165
DomainPSI

PLXNA3 SEMA3G PLXNB3

8.71e-04321103PF01437
DomainPlexin_cytopl

PLXNA3 PLXNB3

1.20e-0391102PF08337
DomainPlexin_cytoplasmic_RasGAP_dom

PLXNA3 PLXNB3

1.20e-0391102IPR013548
DomainPlexin

PLXNA3 PLXNB3

1.20e-0391102IPR031148
DomainEGF_CA

THBS2 SCUBE3 NOTCH1 NOTCH3

1.67e-03861104PF07645
DomainKRAB_RELATED

SSX9P PRDM9

1.83e-03111102PS50806
DomainGAIN_dom_N

ADGRB2 CELSR1

1.83e-03111102IPR032471
DomainGAIN

ADGRB2 CELSR1

1.83e-03111102PF16489
DomainEGF_dom

THBS2 SCUBE3

2.18e-03121102IPR024731
DomainEGF_3

THBS2 SCUBE3

2.18e-03121102PF12947
DomainPSI

PLXNA3 SEMA3G PLXNB3

2.21e-03441103IPR016201
DomainGrowth_fac_rcpt_

LAMA3 CELSR1 SCUBE3 NOTCH1 NOTCH3

2.31e-031561105IPR009030
DomainPSI

PLXNA3 SEMA3G PLXNB3

2.51e-03461103SM00423
DomainKrueppel-associated_box-rel

SSX9P PRDM9

2.57e-03131102IPR003655
Pubmed

Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins.

NPPB TAS1R2 LOXL4 ALK NOTCH1 NOTCH3

1.18e-06101116623382219
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

CFAP47 PDE3B ACACA KIF26B PCARE IRS1 ICE1 NUDT12 FRY DYNC1H1 PLXNB3 FBXO34

6.82e-067361161229676528
Pubmed

Endothelial nitric oxide signaling regulates Notch1 in aortic valve disease.

NOS3 NOTCH1

1.10e-052116223583836
Pubmed

Impaired endothelial function in never-treated hypertensive subjects carrying the Arg972 polymorphism in the insulin receptor substrate-1 gene.

IRS1 NOS3

1.10e-052116215240653
Pubmed

Notch1 promotes ordered revascularization through Semaphorin 3g modulation of downstream vascular patterning signalling factors.

SEMA3G NOTCH1

1.10e-052116234921404
Pubmed

A protein (ORF2) encoded by the latency-related gene of bovine herpesvirus 1 interacts with Notch1 and Notch3.

NOTCH1 NOTCH3

1.10e-052116221191019
Pubmed

Induction of KLF2 by Exercise Activates eNOS to Improve Vasodilatation in Diabetic Mice.

KLF2 NOS3

1.10e-052116237347764
Pubmed

Endothelial nitric oxide synthase controls the expression of the angiogenesis inhibitor thrombospondin 2.

THBS2 NOS3

1.10e-052116221949402
Pubmed

Distinct roles for Notch1 and Notch3 in human adipose-derived stem/stromal cell adipogenesis.

NOTCH1 NOTCH3

1.10e-052116233021719
Pubmed

Nonoverlapping functions for Notch1 and Notch3 during murine steady-state thymic lymphopoiesis.

NOTCH1 NOTCH3

1.10e-052116221768299
Pubmed

Activation of NOTCH1 or NOTCH3 signaling skews human airway basal cell differentiation toward a secretory pathway.

NOTCH1 NOTCH3

1.10e-052116225700162
Pubmed

Evidence of Notch pathway activation in the ectatic ducts of chronic pancreatitis.

NOTCH1 NOTCH3

1.10e-052116218069660
Pubmed

Notch1 and Notch3 coordinate for pericyte-induced stabilization of vasculature.

NOTCH1 NOTCH3

1.10e-052116234878922
Pubmed

T-cells null for the MED23 subunit of mediator express decreased levels of KLF2 and inefficiently populate the peripheral lymphoid organs.

KLF2 MED23

1.10e-052116225054639
Pubmed

Differential regulation of gene expression and insulin-induced activation of phosphodiesterase 3B in adipocytes of lean insulin-resistant IRS-1 (-/-) mice.

PDE3B IRS1

1.10e-052116212213348
Pubmed

A Multi-Omics Approach Using a Mouse Model of Cardiac Malformations for Prioritization of Human Congenital Heart Disease Contributing Genes.

NOS3 NOTCH1

1.10e-052116234504875
Pubmed

The Expression of Notch 1 and Notch 3 in Gallbladder Cancer and Their Clinicopathological Significance.

NOTCH1 NOTCH3

1.10e-052116226634853
Pubmed

Notch3 and IL-1beta exert opposing effects on a vascular smooth muscle cell inflammatory pathway in which NF-kappaB drives crosstalk.

NOTCH1 NOTCH3

1.10e-052116217881497
Pubmed

The common oncogenomic program of NOTCH1 and NOTCH3 signaling in T-cell acute lymphoblastic leukemia.

NOTCH1 NOTCH3

1.10e-052116229023469
Pubmed

Nuclear Notch3 expression is associated with tumor recurrence in patients with stage II and III colorectal cancer.

NOTCH1 NOTCH3

1.10e-052116224728738
Pubmed

Combined deficiency of Notch1 and Notch3 causes pericyte dysfunction, models CADASIL, and results in arteriovenous malformations.

NOTCH1 NOTCH3

1.10e-052116226563570
Pubmed

Characterization of Notch3-deficient mice: normal embryonic development and absence of genetic interactions with a Notch1 mutation.

NOTCH1 NOTCH3

1.10e-052116214595837
Pubmed

Recruitment of insulin receptor substrate-1 and activation of NF-kappaB essential for midkine growth signaling through anaplastic lymphoma kinase.

IRS1 ALK

1.10e-052116216878150
Pubmed

Overexpression of activated murine Notch1 and Notch3 in transgenic mice blocks mammary gland development and induces mammary tumors.

NOTCH1 NOTCH3

1.10e-052116216507912
Pubmed

Maternal nicotine exposure induces congenital heart defects in the offspring of mice.

NPPB NOS3 NOTCH1

1.96e-0516116335521669
Pubmed

Notch Dosage: Jagged1 Haploinsufficiency Is Associated With Reduced Neuronal Division and Disruption of Periglomerular Interneurons in Mice.

DCX NOTCH1 NOTCH3

1.96e-0516116332161758
Pubmed

Multiple genetic variants along candidate pathways influence plasma high-density lipoprotein cholesterol concentrations.

NPPB ACACA ADAMTS4 IRS1 MED23 NOS3 ARHGAP33

2.18e-05250116718660489
Pubmed

The ability of inner-cell-mass cells to self-renew as embryonic stem cells is acquired following epiblast specification.

SOX17 KLF2 LRP6 NOTCH1 NOTCH3

2.21e-05100116524859004
Pubmed

Notch-mediated CBF-1/RBP-J{kappa}-dependent regulation of human vascular smooth muscle cell phenotype in vitro.

NOTCH1 NOTCH3

3.30e-053116215987768
Pubmed

Notch receptor expression in human brain arteriovenous malformations.

NOTCH1 NOTCH3

3.30e-053116225846406
Pubmed

Monocarboxylate transporters (MCTs) in gliomas: expression and exploitation as therapeutic targets.

MCTS1 SLC16A4

3.30e-053116223258846
Pubmed

Complementary and combinatorial patterns of Notch gene family expression during early mouse development.

NOTCH1 NOTCH3

3.30e-05311628645602
Pubmed

Notch/CXCR4 Partnership in Acute Lymphoblastic Leukemia Progression.

NOTCH1 NOTCH3

3.30e-053116231346528
Pubmed

Fractionated radiation suppresses Kruppel-like factor 2 pathway to a greater extent than by single exposure to the same total dose.

KLF2 NOS3

3.30e-053116232382091
Pubmed

Kruppel-like factor 2 as a novel mediator of statin effects in endothelial cells.

KLF2 NOS3

3.30e-053116216043642
Pubmed

PD-L1 and Notch as novel biomarkers in pancreatic sarcomatoid carcinoma: a pilot study.

NOTCH1 NOTCH3

3.30e-053116234846251
Pubmed

Increased expression of monocarboxylate transporters 1, 2, and 4 in colorectal carcinomas.

SLC16A4 SLC16A7

3.30e-053116218188595
Pubmed

Spatiotemporal expression of retrogene-host pair Mcts2/H13 in mouse embryo, and Mcts2 has no influence on H13 transcription pattern in NIH/3T3 cells.

MCTS1 MCTS2

3.30e-053116224063864
Pubmed

Effect of notch1,2,3 genes silicing on NF-κB signaling pathway of macrophages in patients with atherosclerosis.

NOTCH1 NOTCH3

3.30e-053116227697639
Pubmed

NOTCH1 and NOTCH3 coordinate esophageal squamous differentiation through a CSL-dependent transcriptional network.

NOTCH1 NOTCH3

3.30e-053116220801121
Pubmed

Genetic variations in monocarboxylate transporter genes as predictors of clinical outcomes in non-small cell lung cancer.

SLC16A4 SLC16A7

3.30e-053116225578492
Pubmed

Enhanced expression of three monocarboxylate transporter isoforms in the brain of obese mice.

SLC16A4 SLC16A7

3.30e-053116217599960
Pubmed

Hypoxia stimulates lactate release and modulates monocarboxylate transporter (MCT1, MCT2, and MCT4) expression in human adipocytes.

SLC16A4 SLC16A7

3.30e-053116219876643
Pubmed

Expression of Notch 1, 2 and 3 is regulated by epithelial-mesenchymal interactions and retinoic acid in the developing mouse tooth and associated with determination of ameloblast cell fate.

NOTCH1 NOTCH3

3.30e-05311627615640
Pubmed

The novel Notch homologue mouse Notch 3 lacks specific epidermal growth factor-repeats and is expressed in proliferating neuroepithelium.

NOTCH1 NOTCH3

3.30e-05311627918097
Pubmed

B-type natriuretic peptide, vascular endothelial growth factor, endothelin-1, and nitric oxide synthase in chronic mountain sickness.

NPPB NOS3

3.30e-053116221217075
Pubmed

Low density lipoprotein receptor-related protein-1 (LRP1) regulates thrombospondin-2 (TSP2) enhancement of Notch3 signaling.

THBS2 NOTCH3

3.30e-053116220472562
Pubmed

Expression of Notch1 to -4 and their ligands in renal cell carcinoma: a tissue microarray study.

NOTCH1 NOTCH3

3.30e-053116221471519
Pubmed

Smooth muscle Notch1 mediates neointimal formation after vascular injury.

NOTCH1 NOTCH3

3.30e-053116219433762
Pubmed

Notch signaling regulates platelet-derived growth factor receptor-beta expression in vascular smooth muscle cells.

NOTCH1 NOTCH3

3.30e-053116218483410
Pubmed

Identification of the essential extracellular aspartic acids conserved in human monocarboxylate transporters 1, 2, and 4.

SLC16A4 SLC16A7

3.30e-053116232819565
Pubmed

KCTD10 regulates brown adipose tissue thermogenesis and metabolic function via Notch signaling.

NOTCH1 NOTCH3

3.30e-053116234854382
Pubmed

Overlapping but distinct roles for NOTCH receptors in human cardiovascular disease.

NOTCH1 NOTCH3

3.30e-053116229767458
Pubmed

The human NOTCH1, 2, and 3 genes are located at chromosome positions 9q34, 1p13-p11, and 19p13.2-p13.1 in regions of neoplasia-associated translocation.

NOTCH1 NOTCH3

3.30e-05311627698746
Pubmed

Hepatitis B virus X protein and hypoxia‑inducible factor-1α stimulate Notch gene expression in liver cancer cells.

NOTCH1 NOTCH3

3.30e-053116227840976
Pubmed

Human UDP-glucuronosyltransferase UGT2A2: cDNA construction, expression, and functional characterization in comparison with UGT2A1 and UGT2A3.

UGT2A3 UGT2A1

3.30e-053116219858781
Pubmed

Fluid shear stress stimulates phosphorylation-dependent nuclear export of HDAC5 and mediates expression of KLF2 and eNOS.

KLF2 NOS3

3.30e-053116220042720
Pubmed

Class II phosphatidylinositol 3-kinase-C2α is essential for Notch signaling by regulating the endocytosis of γ-secretase in endothelial cells.

NOTCH1 NOTCH3

3.30e-053116233664344
Pubmed

Genome-wide association study of vitamin D levels in children: replication in the Western Australian Pregnancy Cohort (Raine) study.

PDE3B MTMR4 MKLN1

3.37e-0519116325208829
Pubmed

Notch 2 and Notch 1/3 segregate to neuronal and glial lineages of the developing olfactory epithelium.

DCX NOTCH1 NOTCH3

3.37e-0519116316518823
Pubmed

Klf2 is an essential regulator of vascular hemodynamic forces in vivo.

KLF2 NOS3 NOTCH1

5.32e-0522116317141159
Pubmed

SUMOylation of DDX39A Alters Binding and Export of Antiviral Transcripts to Control Innate Immunity.

HUNK NDUFB4 SLC66A1 KLF2 NUDT12 DUOX1 SLC16A4 FAM222B LOXL4 TRIM36 QDPR NOS3

5.75e-059151161232393512
Pubmed

Thrombospondin 2 potentiates notch3/jagged1 signaling.

THBS2 NOTCH3

6.59e-054116219147503
Pubmed

Hepatitis C virus NS3 protein can activate the Notch-signaling pathway through binding to a transcription factor, SRCAP.

NOTCH1 NOTCH3

6.59e-054116221673954
Pubmed

The 4 Notch receptors play distinct and antagonistic roles in the proliferation and hepatocytic differentiation of liver progenitors.

NOTCH1 NOTCH3

6.59e-054116224145721
Pubmed

A switch in Notch gene expression parallels stem cell to endothelial transition in infantile hemangioma.

NOTCH1 NOTCH3

6.59e-054116220069356
Pubmed

A case-by-case evolutionary analysis of four imprinted retrogenes.

MCTS1 MCTS2

6.59e-054116221166792
Pubmed

Expression and clinical significance of Notch receptors in human renal cell carcinoma.

NOTCH1 NOTCH3

6.59e-054116219404845
Pubmed

Notch signaling pathway regulates the growth and the expression of inflammatory cytokines in mouse basophils.

NOTCH1 NOTCH3

6.59e-054116228669409
Pubmed

Mouse jagged1 physically interacts with notch2 and other notch receptors. Assessment by quantitative methods.

NOTCH1 NOTCH3

6.59e-054116210551863
Pubmed

Characterization and developmental expression of the amphioxus homolog of Notch (AmphiNotch): evolutionary conservation of multiple expression domains in amphioxus and vertebrates.

NOTCH1 NOTCH3

6.59e-054116211401408
Pubmed

Functional conservation of mouse Notch receptor family members.

NOTCH1 NOTCH3

6.59e-05411628898100
Pubmed

Notch signalling is linked to epidermal cell differentiation level in basal cell carcinoma, psoriasis and wound healing.

NOTCH1 NOTCH3

6.59e-054116211978185
Pubmed

Par-4/THAP1 complex and Notch3 competitively regulated pre-mRNA splicing of CCAR1 and affected inversely the survival of T-cell acute lymphoblastic leukemia cells.

PAWR NOTCH3

6.59e-054116223975424
Pubmed

p300 and PCAF act cooperatively to mediate transcriptional activation from chromatin templates by notch intracellular domains in vitro.

NOTCH1 NOTCH3

6.59e-054116212391150
Pubmed

Oncogenic activation of the Notch1 gene by deletion of its promoter in Ikaros-deficient T-ALL.

NOTCH1 NOTCH3

6.59e-054116220829372
Pubmed

SoxF factors induce Notch1 expression via direct transcriptional regulation during early arterial development.

SOX17 NOTCH1

6.59e-054116228619820
Pubmed

Monocarboxylate transport in human corneal epithelium and cell lines.

SLC16A4 SLC16A7

6.59e-054116220035863
Pubmed

Notch pathway activity identifies cells with cancer stem cell-like properties and correlates with worse survival in lung adenocarcinoma.

NOTCH1 NOTCH3

6.59e-054116223444212
Pubmed

Deregulated expression of Notch receptors in human hepatocellular carcinoma.

NOTCH1 NOTCH3

6.59e-054116217920003
Pubmed

Analysis of HeyL expression in wild-type and Notch pathway mutant mouse embryos.

NOTCH1 NOTCH3

6.59e-054116211044625
Pubmed

Prognostic roles of mRNA expression of notch receptors in non-small cell lung cancer.

NOTCH1 NOTCH3

6.59e-054116228061457
Pubmed

Maintenance of hematopoietic stem and progenitor cells in fetal intra-aortic hematopoietic clusters by the Sox17-Notch1-Hes1 axis.

SOX17 NOTCH1

6.59e-054116229458175
Pubmed

Evolutionary analysis of vertebrate Notch genes.

NOTCH1 NOTCH3

6.59e-054116211466531
Pubmed

Abnormal expression pattern of Notch receptors, ligands, and downstream effectors in the dorsolateral prefrontal cortex and amygdala of suicidal victims.

NOTCH1 NOTCH3

6.59e-054116224151014
Pubmed

Activation of Notch signaling in human tongue carcinoma.

NOTCH1 NOTCH3

6.59e-054116220819128
Pubmed

Novel MIR143-NOTCH fusions in benign and malignant glomus tumors.

NOTCH1 NOTCH3

6.59e-054116223999936
Pubmed

Interplay between Notch1 and Notch3 promotes EMT and tumor initiation in squamous cell carcinoma.

NOTCH1 NOTCH3

6.59e-054116229170450
Pubmed

Notch as a mediator of cell fate determination in hematopoiesis: evidence and speculation.

NOTCH1 NOTCH3

6.59e-054116210194420
Pubmed

NOTCH1 regulates osteoclastogenesis directly in osteoclast precursors and indirectly via osteoblast lineage cells.

NOTCH1 NOTCH3

6.59e-054116218156632
Pubmed

Conservation of the biochemical mechanisms of signal transduction among mammalian Notch family members.

NOTCH1 NOTCH3

6.59e-054116211459941
Pubmed

Mutational analysis of NOTCH1, 2, 3 and 4 genes in common solid cancers and acute leukemias.

NOTCH1 NOTCH3

6.59e-054116218184405
Pubmed

CDKN1C/P57 is regulated by the Notch target gene Hes1 and induces senescence in human hepatocellular carcinoma.

NOTCH1 NOTCH3

6.59e-054116222705236
Pubmed

Detection of Notch signaling molecules in cemento-ossifying fibroma of the jaws.

NOTCH1 NOTCH3

6.59e-054116220040020
Pubmed

Notch signaling in the mammalian central nervous system: insights from mouse mutants.

NOTCH1 NOTCH3

6.59e-054116215917835
Pubmed

Rbm24/Notch1 signaling regulates adult neurogenesis in the subventricular zone and mediates Parkinson-associated olfactory dysfunction.

DCX NOTCH1

6.59e-054116239113792
Pubmed

Cilostazol Induces eNOS and TM Expression via Activation with Sirtuin 1/Krüppel-like Factor 2 Pathway in Endothelial Cells.

KLF2 NOS3

6.59e-054116234638626
Pubmed

Loss of Gata5 in mice leads to bicuspid aortic valve.

NPPB NOS3 NOTCH1

6.95e-0524116321633169
Pubmed

Hepatic Notch2 deficiency leads to bile duct agenesis perinatally and secondary bile duct formation after weaning.

SOX17 NOTCH1 NOTCH3

8.89e-0526116325446530
Pubmed

Modulation of the notch signaling by Mash1 and Dlx1/2 regulates sequential specification and differentiation of progenitor cell types in the subcortical telencephalon.

GSX2 NOTCH1 NOTCH3

8.89e-0526116312397111
GeneFamilyPlexins

PLXNA3 PLXNB3

5.84e-049742683
CoexpressionDOUGLAS_BMI1_TARGETS_UP

PLXNA3 ACACA SARM1 ADGRB2 HUNK MED13L VSIG10 XYLT2 PAWR NOTCH1 NOTCH3 SH3BP5

6.49e-0656311412M15103
CoexpressionSMID_BREAST_CANCER_BASAL_DN

ACACA ZNF329 ADGRB2 IRS1 SEMA3G MED13L ITGA7 ITPR1 FRY CELSR1 TRIM36 QDPR CLBA1

1.13e-0569911413M4960
CoexpressionDAVICIONI_MOLECULAR_ARMS_VS_ERMS_UP

MED13L JAKMIP2 DCX FRY MTMR4 TRIM36 QDPR ALK NOTCH1

1.84e-053401149M2012
ToppCellLPS_IL1RA-Endothelial-Endothelial-Activated_Alv_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

PDE3B MYLK OAS2 FRY QDPR DYNC1H1 SH3BP5

9.02e-07200115779e51afb57ca38aacebd0298e5e727b55c0cfff9
ToppCellBrain_organoid-organoid_Tanaka_cellReport-6m-Neuronal-Neuron|6m / Sample Type, Dataset, Time_group, and Cell type.

PLXNA3 ADAMTS4 DCX HOXB3 DUOX1 RUNDC3A SPON2

9.02e-072001157b5019b9d48f32cffd4645a5c0f3e0ac504ea8019
ToppCellfacs-Lung-Endomucin-24m-Mesenchymal|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HUNK HOXB3 SPON2 SCUBE3 TRIM36 NOTCH3

5.89e-061731156a37f38478473290fe35aea8684befc3bf95b161f
ToppCellfacs-Lung-24m-Mesenchymal-myofibroblast|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PLXNA3 ITGA7 HOXB3 SPON2 SCUBE3 NOTCH3

6.09e-061741156a7ade7372e83edd4e3983e77f8417b51f0b47340
ToppCellCOVID-19-kidney-Epi_(Mes)|kidney / Disease (COVID-19 only), tissue and cell type

MYLK KIF26B LAMA3 FRY LOXL4 PAWR

7.16e-061791156e7c9dc63f03d3f3746b51a7e3c8393089e2ceb7d
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MYLK ADAMTS4 ZNF2 HOXB3 THBS2 KIAA1755

7.63e-061811156b116c68393d8836bac080f81a8fcbeb52e0403e7
ToppCellRA-13._Vascular_Smooth_Muscle|RA / Chamber and Cluster_Paper

MYLK LAMA3 ITPR1 FRY PAWR NOTCH3

8.13e-061831156818fd886e0188091310825f9145fa53328f2c979
ToppCellRA-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

MYLK LAMA3 ITPR1 FRY PAWR NOTCH3

8.13e-061831156cae2ee08f985a6f005b4b8e959e465350315156a
ToppCellCOVID-19-Fibroblasts-Airway_smooth_muscle|COVID-19 / group, cell type (main and fine annotations)

MYLK KIF26B ITGA7 FRY THBS2 NOTCH3

9.19e-061871156464a0c3b92b778911b5f9cd73642e09e3472063a
ToppCellLA-13._Vascular_Smooth_Muscle|LA / Chamber and Cluster_Paper

MYLK LAMA3 ITPR1 FRY PAWR NOTCH3

9.48e-06188115634e1b074a3995aa46ab194eb45115d76d1a5514d
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PDE3B KIF26B HUNK HOXB3 FRY CRYBG1

9.77e-0618911568ff3c3232eff9de4b5c9b22ecb82bc509d773f58
ToppCellLA-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

MYLK LAMA3 ITPR1 FRY PAWR NOTCH3

9.77e-0618911566b3e88751b95fc2173f2c3d5061ed632d0c5f01c
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PDE3B KIF26B HUNK HOXB3 FRY CRYBG1

1.01e-0519011564836ea19308d2a96694f12ab0653b7ce7b101d2f
ToppCellAdult-Epithelial|Adult / Lineage, Cell type, age group and donor

ACACA LAMA3 DUOX1 CELSR1 LRP6 PAWR

1.07e-051921156efb962a5fd3b9bdfd8cf8d13c435e29c8271713e
ToppCellnucseq-Mesenchymal-Myocytic-Myocytic_2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MYLK KIF26B IRS1 HOXB3 THBS2 NOTCH3

1.10e-0519311565de87fc94a6e58899ef4124cf4887ed3ff96163a
ToppCellnucseq-Mesenchymal-Myocytic|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MYLK KIF26B IRS1 HOXB3 THBS2 NOTCH3

1.13e-0519411562d66091097e106c7bee22e5281f50724700bdf8d
ToppCell(5)_Fibroblasts-(5)_Fibroblast-K_(Pericytes)|(5)_Fibroblasts / Lung cell shreds - cell class (v4) and cell subclass (v4)

MYLK ITGA7 FRY SCUBE3 PAWR NOTCH3

1.20e-051961156541b1fcf509e362f6f48720046cb5378aaf7c591
ToppCellBronchial_Biopsy-Mesenchymal-Smooth_muscle|Mesenchymal / Tissue, Lineage and Cell class of Lung Cells from 10X

SOX17 SEMA3G ITGA7 FRY PAWR NOTCH3

1.24e-05197115698f0184a09563a544f0c2d4df22c9db2fbc95019
ToppCell356C-Fibroblasts-Fibroblast-K_(Pericytes)|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

MYLK ITGA7 ITPR1 FRY SCUBE3 NOTCH3

1.24e-05197115671367bebc23d0e81f60f780d6b0ab3a1783ac014
ToppCell356C-Fibroblasts-Fibroblast-K_(Pericytes)-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

MYLK ITGA7 ITPR1 FRY SCUBE3 NOTCH3

1.24e-0519711560f9836554ace3f9d155ebafdd719aa26466ca44e
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-chondrocyte-like|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYLK PCDHGA5 GAS2 THBS2 SPON2 LOXL4

1.24e-051971156cfd4cc5fb8d7a60dd5c0d2a1a7bad7ba38c19d40
ToppCellTracheal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_systemic_arterial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MYLK ADAMTS4 ADGRB2 ITGA7 FRY NOTCH3

1.27e-0519811567dd874b09c81cc512ccc1e9b65f290a5f94d736e
ToppCellBronchial-10x5prime-Stromal-Pericyte-Muscle_pericyte_systemic|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

MYLK ADAMTS4 LAMA3 ITGA7 C1QTNF6 NOTCH3

1.31e-05199115678a9b26215874a46a910a4b93a51fcac1a597618
ToppCell343B-Fibroblasts-Fibroblast-K_(Pericytes)|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

MYLK ITGA7 FRY SCUBE3 PAWR NOTCH3

1.35e-0520011564fb6fd703aca9a992924245105ad99163146a415
ToppCell343B-Fibroblasts-Fibroblast-K_(Pericytes)-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

MYLK ITGA7 FRY SCUBE3 PAWR NOTCH3

1.35e-052001156b50de1f8c8f598e281951e4587f2d96c11aac836
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KIF26B HUNK HOXB3 CRYBG1 TRIM36

4.54e-05151115510da94037225a71844281ddcb395072250a78094
ToppCellThalamus-Endothelial-ENDOTHELIAL_STALK|Thalamus / BrainAtlas - Mouse McCarroll V32

SOX17 SEMA3G KLF2 SLC16A4 NOS3

5.15e-051551155fe6c4aba0e98cda84bf178aeac2e9fa834477f22
ToppCellmild_COVID-19_(asymptomatic)-B_cell|World / disease group, cell group and cell class (v2)

MYLK VSIG10 PWP2 LRP6 PAWR

5.64e-051581155afa8fa21c39c2192c1e23a4660011d63d58b733f
ToppCellRV-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

MYLK LAMA3 FRY PAWR NOTCH3

5.98e-05160115529c9b4770d0e73d59cffc7937b179484c76b6dcc
ToppCellCOVID-19_Mild-PLT_0|COVID-19_Mild / Disease Group and Platelet Clusters

ICE1 ZNF2 MTMR4 MARCHF4 ARHGAP33

6.92e-051651155083a14d3b0162cee4e79f7398b8fb739582b39ff
ToppCellLV-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

MYLK LAMA3 FRY PAWR NOTCH3

6.92e-051651155f37fd95adc95d7753cf6e55ae819976513c7ec77
ToppCellfacs-Aorta-Heart-24m-Mesenchymal-fibroblast_of_cardiac_tissue|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GAS2 ITGA7 RUNDC3A MOG NOTCH3

7.75e-051691155daed9083ee05c220365200328c2c50047fe21efd
ToppCellfacs-SCAT-Fat-18m-Lymphocytic-T_cell|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFAP47 RAPGEF6 PLCXD2 CELSR1 ARHGAP33

7.75e-051691155700a3a36c379872585204caa6a6cc269b036ae22
ToppCellLV-13._Vascular_Smooth_Muscle|LV / Chamber and Cluster_Paper

MYLK LAMA3 FRY PAWR NOTCH3

8.19e-051711155e99ecae66530d1ae09330cee408c8f3950b87e67
ToppCell368C-Endothelial_cells-Endothelial-B_(Artery)-|368C / Donor, Lineage, Cell class and subclass (all cells)

SOX17 SEMA3G ITPR1 FRY NOS3

8.65e-051731155ec88e871b49331fca59bc610a8ae58e2d5e76bc1
ToppCellfacs-Marrow-KLS-3m-Lymphocytic-immature_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAA15 ACACA RBM12B USP37 ARHGAP33

8.65e-0517311558bffd512a4e561e23cc04478e2ca6fd5d3771fe4
ToppCellfacs-Marrow-KLS-3m-Lymphocytic-immature_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAA15 ACACA RBM12B USP37 ARHGAP33

8.65e-0517311553e3c61468e703330788a10d850ef41a85680f86d
ToppCell368C-Endothelial_cells-Endothelial-B_(Artery)|368C / Donor, Lineage, Cell class and subclass (all cells)

SOX17 SEMA3G ITPR1 FRY NOS3

8.65e-05173115522200fe74e33e2beae0eed289ca8476bbc0b1b2d
ToppCelldroplet-Fat-SCAT-30m-Endothelial-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RBM12B KIF26B SOX17 SEMA3G KLF2

8.65e-051731155eb58b0189e71e38d4f4f1cf544a82cde8d1c86bc
ToppCelldroplet-Thymus-nan-21m-Lymphocytic-Double_negative_thymocyte,_DN3_(Cd8-,_Cd4-),_some_express_pre_TCR_alpha|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCDC9B IRS1 HUNK NOTCH1 NOTCH3

8.89e-051741155a9f34d1237f335d27c5560ff514368f4709f9144
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Immune-Lymphocytic_T/NK-T_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PDE3B PSTPIP1 IL18RAP JAKMIP2 MARCHF4

8.89e-05174115547e308a777c927ae69ed344cb3dd8561bf2c48a5
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Immune-Lymphocytic_T/NK-T_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PDE3B PSTPIP1 IL18RAP JAKMIP2 MARCHF4

8.89e-051741155a92c745d20633909db0f08effa13fc738fda79a6
ToppCellfacs-Skin-Telogen-3m-Lymphocytic-nan|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE3B MYLK ADGRB2 PSTPIP1 C1QTNF6

9.38e-0517611553d372c1d527fcc118d1e5809f2524fc387682472
ToppCellfacs-Skin-Telogen-3m-Lymphocytic|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE3B MYLK ADGRB2 PSTPIP1 C1QTNF6

9.38e-0517611557b3f3d9b33770edf294cee0eccaf8a46f9331461
ToppCellfacs-Skin-Telogen-3m-Lymphocytic-T_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE3B MYLK ADGRB2 PSTPIP1 C1QTNF6

9.38e-0517611559c0fb2c6ae84febdf7c3d4e648985f597dcffe7a
ToppCell5'-Adult-Appendix-Mesenchymal-myocytic-myofibroblast|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYLK IRS1 GPR75 KIAA1755 PLXNB3

9.63e-051771155e65c0568dc5852108e9802273499bc7cf88fafab
ToppCelldroplet-Heart-nan-3m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYLK ITGA7 SCUBE3 PAWR NOTCH3

9.63e-051771155dbdbdc8ed9ef0b529694242ef9f9f07a42e16005
ToppCelldroplet-Heart-nan-3m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYLK ITGA7 SCUBE3 PAWR NOTCH3

9.89e-051781155416f85e51f45ec7949451fd47611a84e33e87245
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid-lung_macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OAS2 SLC66A1 SCMH1 MED23 PLXNB3

1.02e-0417911552c3abd646d2c8992e8ff76a824eab5beba8ba4c6
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid-Interstitial_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OAS2 SLC66A1 SCMH1 MED23 PLXNB3

1.02e-0417911556eb84fe9691ad40127b2d1f1c672428333c8fab4
ToppCellCOVID-19-Heart-VSMC|Heart / Disease (COVID-19 only), tissue and cell type

MYLK ADAMTS4 LAMA3 PAWR NOTCH3

1.02e-041791155a69ad6912b5c10bb9f9d800f724c792341e9bab1
ToppCell3'-Parenchyma_lung-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SOX17 SEMA3G KLF2 FRY NOS3

1.02e-041791155d2db9e70b780643f1e004c41a70464d0abe26088
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SOX17 SEMA3G KLF2 NOS3 NOTCH1

1.07e-0418111554d7793026373cbcf04b15c77f95f1025d07d4c00
ToppCellFetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SLC17A2 MYLK IRS1 HOXB3 SPON2

1.07e-041811155d7e04e0ca549eac6d9b1192b6578f9b54943d54f
ToppCellfacs-Spleen-nan-3m-Lymphocytic-Cd3e_T_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE3B RAPGEF6 PLCXD2 CELSR1 NOTCH1

1.07e-041811155be7c7db6b99603759593e6f79cdcaa4bbf234cb7
ToppCellfacs-Lung-Endomucin-24m-Mesenchymal-pericyte_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HUNK HOXB3 SCUBE3 TRIM36 NOTCH3

1.10e-041821155be9c312a44868d4ee266a64d066feb8c5bce5687
ToppCellfacs-Lung-Endomucin-24m-Mesenchymal-Pericyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HUNK HOXB3 SCUBE3 TRIM36 NOTCH3

1.10e-04182115574dbb706bcaa0f8c922bf3b0424bce5bb27167fa
ToppCell3'-Broncho-tracheal-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell-SM_activated_stress_response-SM_activated_stress_response_L.2.3.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MYLK ADAMTS4 ITGA7 KLF2 NOTCH3

1.10e-04182115597bb07478f56a937b490fba121ee603db64134a1
ToppCelldroplet-Limb_Muscle-nan-21m-Macroglial-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HUNK OTOP1 MOG PLXNB3 ARHGAP33

1.10e-041821155a512863304fad80acaab60a8c6107eb7c9cbac99
ToppCell3'-Broncho-tracheal-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell-SM_activated_stress_response|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MYLK ADAMTS4 ITGA7 KLF2 NOTCH3

1.10e-0418211551c1a687f728341c209b048b6715bcddd0ac20069
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX17 OAS2 KLF2 FRY NOS3

1.10e-041821155ef65b095f4240d61cfd4a59aec19d72d324dba1d
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX17 OAS2 KLF2 FRY NOS3

1.10e-04182115597a805783a1f2b055c21307db250e3688674eff3
ToppCellwk_15-18-Epithelial-PNS-Late_Schwann|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

CCDC9B SEMA3G SLC16A4 KIAA1755 PLXNB3

1.10e-0418211556462e0469224457e249d10e224082f727caa02d6
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SOX17 SEMA3G KLF2 NOS3 NOTCH1

1.13e-0418311553427f3cbe6ea81709750e7dd3ff378f03ae65eab
ToppCellwk_15-18-Epithelial-PNS-Early_Schwann|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

DCX RUNDC3A KIAA1755 ALK MOG

1.13e-0418311557e8366ec8117d36cec67f77dcb0e9a6032d87fcb
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM2_(12)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

MYLK KIF26B IRS1 KIAA1755 MARCHF4

1.13e-041831155e84539978ab4de42e19186aed00f24bb50cbc21f
ToppCellControl-Stromal-SMC|World / Disease state, Lineage and Cell class

MYLK ADAMTS4 ITGA7 HOXB3 NOTCH3

1.16e-04184115588b1a4c9a96a99fc3a39f7a2c3d0838739606f3e
ToppCellfacs-Lung-24m-Mesenchymal-myofibroblast-pericyte_cell-pericyte|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HUNK ITGA7 SPON2 SCUBE3 NOTCH3

1.19e-041851155a6cd90f8f30c7bdf66958cf403e73c193aa32f5e
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-Pericytes-angiogenic_pericyte|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADAMTS4 LAMA3 ITGA7 FRY NOTCH3

1.19e-04185115535d39a1d04c871edcfb749653538dc5fd0054281
ToppCellfacs-Lung-24m-Mesenchymal-myofibroblast-pericyte_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HUNK ITGA7 SPON2 SCUBE3 NOTCH3

1.19e-0418511555053f932e2adfcf4d6faaecff2999ac53d8d7aa5
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_OPALIN|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ADAMTS4 KIAA1755 QDPR MOG PLXNB3

1.19e-0418511551d731d69d8db8aef4a11439b8abd1030c7e6ac4c
ToppCell3'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_B-Branch_B3_(IPAN)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PLCXD2 DCX FRY RUNDC3A MARCHF4

1.19e-041851155edb114487206e4e8df4c7878285df40f49b7fd64
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ADAMTS4 KIAA1755 QDPR MOG PLXNB3

1.19e-041851155b8d02c9426740ffcb69d2e6f95473b388149d297
ToppCell5'-GW_trimst-2-LymphNode-Mesenchymal-Pericytes|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LAMA3 ITGA7 FRY PAWR NOTCH3

1.22e-0418611551e3ab663e4756975db6d802b2c6c054a94a79393
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ADAMTS4 KIAA1755 QDPR MOG PLXNB3

1.22e-04186115590eaf6ffb4ce0c34fa1e79f0c8f36f217f44973b
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Mesenchymal-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYLK SOX17 SEMA3G NOTCH1 NOTCH3

1.22e-0418611554ae3c0fe8640a8d029875cf3f0f5ffbba38e85f8
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_OPALIN|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ADAMTS4 KIAA1755 QDPR MOG PLXNB3

1.22e-041861155bd8a9753df219084e19e7f94447856e86608325c
ToppCell5'-GW_trimst-2-LymphNode-Mesenchymal-Pericytes-angiogenic_pericyte|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LAMA3 ITGA7 FRY PAWR NOTCH3

1.25e-041871155b8f88599e22b9b345c7ec3bbecd87a8b2a033f9f
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_OPALIN|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ADAMTS4 KIAA1755 QDPR MOG PLXNB3

1.25e-041871155f0de86ef25e344d9b1860ee26308877d6c25ed31
ToppCelldroplet-Heart-nan-18m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYLK SARM1 ITGA7 SCUBE3 NOTCH3

1.25e-04187115559313a47a6012b2413d7d3673bb05fb7e49fd88f
ToppCelldroplet-Heart-nan-18m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYLK SARM1 ITGA7 SCUBE3 NOTCH3

1.25e-0418711552591fe1552cd10925ad1d8d1f062a057ce6bdad9
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ADAMTS4 KIAA1755 QDPR MOG PLXNB3

1.25e-041871155b71d0cd91bc98e020757c1d071a13ad48d718bcf
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PDE3B HUNK HOXB3 FRY CRYBG1

1.25e-041871155f6217d0dd425eac76900b44a4e48f45475f3ac36
ToppCellP03-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_artery|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

SOX17 SEMA3G KLF2 NOS3 NOTCH1

1.25e-04187115566ebe1788d51b3e17bec6cdb219f709756b4e530
ToppCellP07-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_artery|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

SOX17 SEMA3G KLF2 NOS3 NOTCH1

1.28e-0418811555bc1537e079c7435196c163bff5f639ea392a33a
ToppCelldroplet-Kidney-nan-3m-Epithelial-Pecam____Kidney_cortex_artery_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX17 SEMA3G THBS2 NOS3 NOTCH3

1.28e-041881155ec0e241de2c8310b4417b9d4e2420d7a1662f1c0
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRB2 LAMA3 FRY LOXL4 PAWR

1.28e-041881155b21e93a70583c30d05c0833cd3d4d4bca44a039e
ToppCellControl-Endothelial-VE_Capillary_A|Endothelial / Disease state, Lineage and Cell class

PDE3B MYLK FRY SPON2 SH3BP5

1.28e-04188115588b3415e33db81726dd29c1f50c886e057af50a0
ToppCellFetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

MYLK KIF26B IRS1 ITGA7 THBS2

1.28e-041881155c29aaae3c5bb7cd6b9b3defd4d27afde3af19ba0
ToppCellFetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

MYLK KIF26B IRS1 THBS2 PAWR

1.28e-0418811554d1e5f85342ae550086609d7680e32730b78b5d2
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Oligo|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ADAMTS4 THBS2 KIAA1755 MOG PLXNB3

1.28e-041881155d9692b6048d9b85524a07a1807bdd4757731c151
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRB2 LAMA3 FRY LOXL4 PAWR

1.28e-041881155874404a4fd9aa42873f6c53dc42da22d3b0fdb9e
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_OPALIN|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ADAMTS4 KIAA1755 QDPR MOG PLXNB3

1.31e-041891155b60c8a29d3169c4830fe63b01db90c57660fc239
ToppCellPND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SOX17 SEMA3G KLF2 NOS3 NOTCH1

1.31e-0418911559da012fdfa9a8d488cab710a463a1d70e89f990c
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SOX17 SEMA3G OVCH1 KLF2 NOS3

1.31e-04189115512b6f1c3bf526b90e112374bf937701f645c5780
ToppCellPND01-Endothelial-Endothelial_blood-vessel-Macrovascular_EC|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SOX17 SEMA3G KLF2 NOS3 NOTCH1

1.31e-0418911551e1afa66b32ae752c0a42b02b80f10205464569c
ToppCellfacs-GAT-Fat-24m-Endothelial-nan|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX17 FRY NOS3 NOTCH1 SH3BP5

1.34e-041901155da2fcd4a2cc6e45c8174109d892f1424e39919a1
ToppCellfacs-Heart-RV-3m-Endothelial-endothelial_cell_of_coronary_artery|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX17 KLF2 FRY NOS3 NOTCH1

1.34e-04190115589d1d686cc683206534e2157554d7d0df5d53497
ToppCellfacs-GAT-Fat-24m-Endothelial|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX17 FRY NOS3 NOTCH1 SH3BP5

1.34e-0419011553395b2ff6ffadf84cdb1b5a37a5b6be05b56c30f
ToppCellPND01-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SOX17 SEMA3G KLF2 NOS3 NOTCH1

1.34e-041901155eae5bcdb8a35f3fba4d25854c1a43f83f80832a2
ComputationalGenes in the cancer module 162.

SLC17A2 SLC16A4 SLC16A7

2.59e-0419723MODULE_162
ComputationalGenes in the cancer module 218.

SLC17A2 SLC16A4 SLC16A7

3.03e-0420723MODULE_218
DrugLevopropoxyphene napsylate [5714-90-9]; Up 200; 7.4uM; PC3; HT_HG-U133A

NPPB ADGRB2 DCX PRDM9 RUNDC3A SLC16A4 ALOXE3 NOTCH3 LILRA4

5.77e-0719711295083_UP
DiseaseCongenital aneurysm of ascending aorta

MYLK NOTCH1

1.28e-0521062C0345050
Diseaseobesity (implicated_via_orthology)

ADAMTS4 IRS1 MED13L ITPR1 NOTCH1 PLXNB3 NOTCH3

1.31e-052151067DOID:9970 (implicated_via_orthology)
Diseaselissencephaly (implicated_via_orthology)

DCX NOS3 DYNC1H1

1.24e-04271063DOID:0050453 (implicated_via_orthology)
Diseasetransient cerebral ischemia (biomarker_via_orthology)

ADAMTS4 ITPR1 PAWR NOS3 NOTCH1

2.63e-041571065DOID:224 (biomarker_via_orthology)
Diseaseadenocarcinoma (implicated_via_orthology)

NOTCH1 NOTCH3

2.65e-0471062DOID:299 (implicated_via_orthology)
Diseasecentral nervous system cancer (implicated_via_orthology)

NOTCH1 NOTCH3

2.65e-0471062DOID:3620 (implicated_via_orthology)
DiseaseTachycardia, Ventricular

NPPB NOS3

6.88e-04111062C0042514
DiseaseOligospermia

NOS3 BRWD1

8.24e-04121062C0028960
Diseaseright ventricular stroke volume measurement

KIAA1755 NOS3

8.24e-04121062EFO_0021817
DiseaseFamilial thoracic aortic aneurysm and aortic dissection

MYLK SKI NOTCH1

9.26e-04531063C4707243
Diseasepolycystic kidney disease (implicated_via_orthology)

NPPB XYLT2

1.13e-03141062DOID:0080322 (implicated_via_orthology)
DiseaseDiabetic Angiopathies

THBS2 NOS3

1.48e-03161062C0011875
Diseaseatherosclerosis (is_implicated_in)

NPPB NOS3

1.48e-03161062DOID:1936 (is_implicated_in)
DiseaseMicroangiopathy, Diabetic

THBS2 NOS3

1.48e-03161062C0025945
DiseaseHuntington's disease (biomarker_via_orthology)

ITPR1 NOS3

1.48e-03161062DOID:12858 (biomarker_via_orthology)
DiseaseProfound Mental Retardation

NAA15 MED13L FRY DYNC1H1

1.62e-031391064C0020796
DiseaseMental Retardation, Psychosocial

NAA15 MED13L FRY DYNC1H1

1.62e-031391064C0025363
DiseaseMental deficiency

NAA15 MED13L FRY DYNC1H1

1.62e-031391064C0917816
DiseaseCoronary Arteriosclerosis

NPPB IRS1 NOS3

1.67e-03651063C0010054
DiseaseCoronary Artery Disease

NPPB IRS1 NOS3

1.67e-03651063C1956346
DiseaseSLAM family member 7 measurement

ADAMTS4 SARM1

1.68e-03171062EFO_0008287
DiseaseLipidemias

IRS1 NOS3

1.68e-03171062C1706412
DiseaseHyperlipidemia

IRS1 NOS3

1.68e-03171062C0020473
Diseasebrain infarction

THBS2 ALK

1.88e-03181062EFO_0004277
DiseaseAlzheimer's disease (is_marker_for)

IRS1 ITPR1 PAWR NOS3 DYNC1H1

2.39e-032571065DOID:10652 (is_marker_for)
Diseasepulmonary hypertension (biomarker_via_orthology)

NPPB SOX17 NOS3

3.03e-03801063DOID:6432 (biomarker_via_orthology)
DiseaseUreteral obstruction

NPPB NOS3

3.35e-03241062C0041956
DiseaseCarcinoma, Pancreatic Ductal

NOTCH1 NOTCH3

3.35e-03241062C0887833

Protein segments in the cluster

PeptideGeneStartEntry
SRMRTCVPPQHGGKA

ADGRB2

386

O60241
MFPVLGPRSECSGAS

SH3BP5

361

O60239
LSGLAPGPFCAMVLA

AMACR

11

Q9UHK6
PFGILSPNVLCSMSG

FBXO34

61

Q9NWN3
LLDNSFTPPCQRMGG

ACACA

1221

Q13085
PLRFGGKNCEQAMPH

CELSR1

1676

Q9NYQ6
CQSLAGKNSGMPPGA

QDPR

161

P09417
PLGKGAMVASFSPAA

DCP1A

411

Q9NPI6
PRPLAFCSFGSRLMG

ATXN7L1

461

Q9ULK2
FMPDPKINCGSGRVT

RBM12B

911

Q8IXT5
CAVGSAMLTRAAPGP

PAWR

91

Q96IZ0
PGFCARARVPMPSNK

IWS1

746

Q96ST2
PFMLLGTLCEPGSGQ

PCDHGA5

16

Q9Y5G8
SNMGARSKGQCPEPP

PTPN9

496

P43378
QVRKIGVFSCGPPGM

DUOX1

1511

Q9NRD9
TSSPGIQPSCGMIKR

PSTPIP1

296

O43586
PGVNNSGSYICRPKM

IL18RAP

116

O95256
CNMSSPKREIPGRAG

JAKMIP2

256

Q96AA8
KLRPACPGGMHAVVS

LOXL4

271

Q96JB6
PMGPLTFSNRGTFRC

LILRA4

181

P59901
QMGRFSCKITGRPQP

MYLK

176

Q15746
VRGPDGFTPLMIASC

NOTCH1

1876

P46531
LSGANIMCPGLTSPG

MCTS1

106

Q9ULC4
LSGANIMCPGLTSPG

MCTS2

106

A0A3B3IRV3
GLGSVKDPSNCGMPL

MED13L

311

Q71F56
GCSLNKPPFLMLLKG

LAMA3

2926

Q16787
KLLQAPFTDCGDGPM

ITPR1

521

Q14643
PPGGMQEATRCLSKS

KIAA1755

751

Q5JYT7
GMACATPLLSAAGPV

SLC66A1

141

Q6ZP29
PLGCTMAPGARNVFV

KRT37

11

O76014
SGFPSRLCTPGEMVK

ALOXE3

561

Q9BYJ1
NSCGFVEGKPRPMGS

KIF26B

1051

Q2KJY2
PLGCTMAPGARNVSV

KRT38

11

O76015
PRGCSGILSVPAVAM

CCDC9B

31

Q6ZUT6
LVMSVSGPGCPSRKS

GSX2

41

Q9BZM3
LISALLGTKMPGPGC

HTD2

91

P86397
LGTKMPGPGCVFLSQ

HTD2

96

P86397
AMLCKAPGIFLGRPQ

PLXNA3

1076

P51805
GPRGTQAALCAFPMV

PLXNB3

306

Q9ULL4
LMGAFSGSCRPKINP

PDE3B

386

Q13370
MLACLPGPGDLSFQL

FAM222B

1

Q8WU58
RIPLPGTNCMASGSI

MED23

506

Q9ULK4
TPLMLASFCGGALEP

NOTCH3

1791

Q9UM47
SASPGCGRPSSNKML

FAM157C

126

P0CG43
LNACVAGSLMRPLGP

SLC16A7

186

O60669
GGCSHLCLMSPVKPF

LRP6

291

O75581
PRSPKMVQGSGCFGR

NPPB

101

P16860
ICMGGKGPSTLTAPN

IRS1

466

P35568
KVPTMQTPGSCGARI

OAS2

681

P29728
RPTPKNSLMGALCGF

NDUFB4

81

O95168
MVLGKQPNRTASFPC

GPR75

146

O95800
LPCRISPGKNATGME

MOG

51

Q16653
MNFSKGCPPVFNTLR

NAA15

316

Q9BXJ9
RPNSKQMRATGPCFG

MTMR4

936

Q9NYA4
GLQPTPMTLVFGCRC

NOS3

1036

P29474
FSSPPKGQMGSCRVG

PRDM9

476

Q9NQV7
TMPLASSCPKSGGVA

OTOP1

471

Q7RTM1
MCSKLRGAQGPLGPD

ARHGAP33

856

O14559
ASFPRMNGPAGKSFV

DERPC

476

P0CG12
LRRKSPASGQGPMCN

ADAMTS4

181

O75173
ADCKNLPGPASAMIG

ICE1

1781

Q9Y2F5
EMGSPGAPCQKRFFA

C1QTNF6

131

Q9BXI9
TGCSMNPARSFGPAI

AQP6

191

Q13520
CRVMKGNPSATAGPK

DCX

271

O43602
SKELNGSCMRPGLAP

HOXB3

66

P14651
LGSPNCVKSRGRFPM

HUNK

651

P57058
GAPEGSKMLRATAPC

REXO1L1P

86

Q8IX06
CPSVKFRPGLPAMAL

DUX3

16

Q96PT4
PRPGVQMLCSSFSVG

BRWD1

321

Q9NSI6
SGMRTPLCRICFQGP

MARCHF4

156

Q9P2E8
LVLCGPPGSGKTMTL

DYNC1H1

2591

Q14204
GISPLRLCGSPDSMF

ITGA7

411

Q13683
IGMFLLSGDPCFKTP

FAM102A

141

Q5T9C2
LCFGVAKPSIMSPGH

FRY

921

Q5TBA9
MGCPPGATFKSLRFI

CRYBG1

1481

Q9Y4K1
PMESCRPGQHRAGTK

SCUBE3

621

Q8IX30
GPVLNFKPCFMGERS

CFAP47

416

Q6ZTR5
SGRPQDCLLSGAPMA

PCARE

406

A6NGG8
MCTALSPKVRSGPGL

GAS2

1

O43903
KDPTPSMLGLCGSLA

RUNDC3A

401

Q59EK9
TQSALPAVMAGLGPC

SOX17

16

Q9H6I2
GKSAAPLIICPMSGI

TRIM27

481

P14373
PMPTSIGIFLDCDKG

TRIM36

661

Q9NQ86
GSMVLPPCSFGKQFG

RAPGEF6

86

Q8TEU7
MENPSPAAALGKALC

SPON2

1

Q9BUD6
FGGNPGKSCSPKMRL

MKLN1

601

Q9UL63
MNLPPLGRTMLCAGF

OVCH1

211

Q7RTY7
RQKRFPPGMFTCLAG

NUDT12

341

Q9BQG2
VLMASLPFCGPNGID

OR6T1

161

Q8NGN1
LKVMGILPFSAPSCG

SKI

161

P12755
CEKNGGMLQPPLGFR

SCMH1

116

Q96GD3
FVTSGGRMDPPKNCP

ALK

1341

Q9UM73
PPGSKQGRLMTCSRF

CLBA1

276

Q96F83
DPGKKFSGRPMCTLL

CNOT10

336

Q9H9A5
FKSSPLMGCFLFGLP

TMX3

371

Q96JJ7
LCPKFEVHTPNGRMG

ZNF2

121

Q9BSG1
PFLCVTMGLLPGLGS

SLC16A4

111

O15374
ASLPDPILGGMFCTL

SLC23A1

421

Q9UHI7
KLCRFFAMSGPRPGA

SARM1

11

Q6SZW1
LRMGTICSPNPSGTK

PLCXD2

11

Q0VAA5
GTLQCPESGRMFPIS

TRMT112

96

Q9UI30
ARGAGESCPTFPKMV

TMEM247

11

A6NEH6
EGPISGLCFNPMKSV

PWP2

501

Q15269
LGFKATLPPFMCNTG

SSX9P

61

Q7RTT3
MDGKPATRKGPDFCS

SLC17A2

1

O00624
MSDNGGFKRPLAPSG

TSSC4

116

Q9Y5U2
FQTPIVRSAGGPMCF

TAS1R2

591

Q8TE23
RLPAAMKPSQGSGSF

USP37

106

Q86T82
TCGLLMSLGCPLFKP

ZNF543

41

Q08ER8
GNMERSCGKLPAPLS

UGT2A3

176

Q6UWM9
PSLLSEPMKTCFTGG

VSIG10

311

Q8N0Z9
VCPSKMTAQPGRPFG

SEMA3G

381

Q9NS98
ELIGGPPKTRNMSAC

THBS2

306

P35442
PAGRPTTLCETMGKA

UGT2A1

281

P0DTE4
SREGPSRCPQCGKMF

ZNF329

506

Q86UD4
AVPRHCQLTGKMSPG

XYLT2

201

Q9H1B5
SGCYMLLDPKNARPG

ZAN

256

Q9Y493
GLKREGAPGPAASCM

KLF2

146

Q9Y5W3