Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	fatty acyl-CoA hydrolase activity	ACOT1 ACOT6 ACOT4	6.81e-05	27	59	3	GO:0047617
GeneOntologyMolecularFunction	acyl-CoA hydrolase activity	ACOT1 ACOT6 ACOT4	7.62e-05	28	59	3	GO:0016289
GeneOntologyMolecularFunction	protein-cysteine S-myristoyltransferase activity	ZDHHC15 ZDHHC17	1.28e-04	6	59	2	GO:0019705
GeneOntologyMolecularFunction	protein-cysteine S-stearoyltransferase activity	ZDHHC15 ZDHHC17	1.79e-04	7	59	2	GO:0140439
GeneOntologyMolecularFunction	thiolester hydrolase activity	ACOT1 ACOT6 ACOT4	3.62e-04	47	59	3	GO:0016790
GeneOntologyMolecularFunction	acyltransferase activity	ZDHHC15 FBXO24 TRIM11 PELI3 SHARPIN FBXO17 ZDHHC17 RNF39 DDB2	4.21e-04	775	59	9	GO:0016746
GeneOntologyMolecularFunction	myristoyltransferase activity	ZDHHC15 ZDHHC17	4.64e-04	11	59	2	GO:0019107
GeneOntologyMolecularFunction	ubiquitin-protein transferase activity	FBXO24 TRIM11 PELI3 SHARPIN FBXO17 RNF39 DDB2	4.71e-04	473	59	7	GO:0004842
GeneOntologyMolecularFunction	ubiquitin-like protein transferase activity	FBXO24 TRIM11 PELI3 SHARPIN FBXO17 RNF39 DDB2	7.53e-04	512	59	7	GO:0019787
GeneOntologyMolecularFunction	aminoacyltransferase activity	FBXO24 TRIM11 PELI3 SHARPIN FBXO17 RNF39 DDB2	9.42e-04	532	59	7	GO:0016755
GeneOntologyMolecularFunction	low-density lipoprotein particle receptor activity	LRP1B LRP8	1.00e-03	16	59	2	GO:0005041
GeneOntologyMolecularFunction	carboxylic ester hydrolase activity	ABHD15 ACOT1 ACOT6 ACOT4	1.20e-03	157	59	4	GO:0052689
GeneOntologyMolecularFunction	calcium ion binding	DGKA NID1 RET LRP1B LETM1 NOTCH3 PROC LRP8	1.54e-03	749	59	8	GO:0005509
GeneOntologyMolecularFunction	lipoprotein particle receptor activity	LRP1B LRP8	1.74e-03	21	59	2	GO:0030228
GeneOntologyMolecularFunction	collagen binding	VWF NID1 TNXB	1.78e-03	81	59	3	GO:0005518
GeneOntologyMolecularFunction	extracellular matrix structural constituent	VWF NID1 SSPOP TNXB	2.31e-03	188	59	4	GO:0005201
GeneOntologyMolecularFunction	transforming growth factor beta binding	WFIKKN1 ACVRL1	2.67e-03	26	59	2	GO:0050431
GeneOntologyMolecularFunction	protein-cysteine S-palmitoyltransferase activity	ZDHHC15 ZDHHC17	2.67e-03	26	59	2	GO:0019706
GeneOntologyMolecularFunction	protein-cysteine S-acyltransferase activity	ZDHHC15 ZDHHC17	2.67e-03	26	59	2	GO:0019707
GeneOntologyMolecularFunction	S-acyltransferase activity	ZDHHC15 ZDHHC17	3.54e-03	30	59	2	GO:0016417
GeneOntologyMolecularFunction	palmitoyltransferase activity	ZDHHC15 ZDHHC17	5.35e-03	37	59	2	GO:0016409
GeneOntologyBiologicalProcess	saturated monocarboxylic acid metabolic process	ACOT1 ACOT4	8.04e-06	2	59	2	GO:0032788
GeneOntologyBiologicalProcess	unsaturated monocarboxylic acid metabolic process	ACOT1 ACOT4	8.04e-06	2	59	2	GO:0032789
MousePheno	absent ureter	FMN1 RET GDF11	3.54e-05	19	48	3	MP:0003722
MousePheno	abnormal brain thrombosis	NOTCH3 PROC	6.90e-05	4	48	2	MP:0031168
Domain	BAAT_C	ACOT1 ACOT6 ACOT4	2.83e-07	5	58	3	IPR014940
Domain	BAAT_C	ACOT1 ACOT6 ACOT4	2.83e-07	5	58	3	PF08840
Domain	EGF	NID1 LRP1B TNXB NOTCH3 PROC LRP8	2.54e-06	126	58	6	PF00008
Domain	TIL	VWF MUC5B SSPOP	6.13e-06	12	58	3	PF01826
Domain	C8	VWF MUC5B SSPOP	6.13e-06	12	58	3	PF08742
Domain	Unchr_dom_Cys-rich	VWF MUC5B SSPOP	7.95e-06	13	58	3	IPR014853
Domain	C8	VWF MUC5B SSPOP	7.95e-06	13	58	3	SM00832
Domain	EGF_3	NID1 LRP1B SSPOP TNXB NOTCH3 PROC LRP8	7.95e-06	235	58	7	PS50026
Domain	Growth_fac_rcpt_	NID1 HTRA3 LRP1B TNXB NOTCH3 LRP8	8.72e-06	156	58	6	IPR009030
Domain	TIL_dom	VWF MUC5B SSPOP	1.01e-05	14	58	3	IPR002919
Domain	Ldl_recept_b	NID1 LRP1B LRP8	1.01e-05	14	58	3	PF00058
Domain	LDLRB	NID1 LRP1B LRP8	1.01e-05	14	58	3	PS51120
Domain	EGF_Ca-bd_CS	NID1 LRP1B NOTCH3 PROC LRP8	1.25e-05	97	58	5	IPR018097
Domain	LY	NID1 LRP1B LRP8	1.26e-05	15	58	3	SM00135
Domain	LDLR_classB_rpt	NID1 LRP1B LRP8	1.26e-05	15	58	3	IPR000033
Domain	EGF_1	NID1 LRP1B SSPOP TNXB NOTCH3 PROC LRP8	1.35e-05	255	58	7	PS00022
Domain	EGF_CA	NID1 LRP1B NOTCH3 PROC LRP8	1.39e-05	99	58	5	PS01187
Domain	ASX_HYDROXYL	NID1 LRP1B NOTCH3 PROC LRP8	1.46e-05	100	58	5	PS00010
Domain	VWD	VWF MUC5B SSPOP	1.55e-05	16	58	3	SM00216
Domain	VWF_type-D	VWF MUC5B SSPOP	1.55e-05	16	58	3	IPR001846
Domain	VWFD	VWF MUC5B SSPOP	1.55e-05	16	58	3	PS51233
Domain	VWD	VWF MUC5B SSPOP	1.55e-05	16	58	3	PF00094
Domain	EGF_2	NID1 LRP1B SSPOP TNXB NOTCH3 PROC LRP8	1.73e-05	265	58	7	PS01186
Domain	EGF-type_Asp/Asn_hydroxyl_site	NID1 LRP1B NOTCH3 PROC LRP8	1.93e-05	106	58	5	IPR000152
Domain	RasGAP_dom	RASA4 RASA4B PLXNB1	2.24e-05	18	58	3	IPR001936
Domain	CTCK_1	VWF MUC5B SSPOP	2.24e-05	18	58	3	PS01185
Domain	VWC_out	VWF MUC5B SSPOP	2.66e-05	19	58	3	SM00215
Domain	-	RASA4 RASA4B	2.84e-05	3	58	2	4.10.1130.10
Domain	EGF_CA	NID1 LRP1B NOTCH3 PROC LRP8	3.80e-05	122	58	5	SM00179
Domain	EGF-like_Ca-bd_dom	NID1 LRP1B NOTCH3 PROC LRP8	4.11e-05	124	58	5	IPR001881
Domain	Bile_Hydr_Trans	ACOT1 ACOT4	5.66e-05	4	58	2	PF04775
Domain	Thio_Ohase/aa_AcTrfase	ACOT1 ACOT4	5.66e-05	4	58	2	IPR006862
Domain	Acyl-CoA_thioEstase_long-chain	ACOT1 ACOT4	5.66e-05	4	58	2	IPR016662
Domain	Cys_knot_C	VWF MUC5B SSPOP	6.23e-05	25	58	3	IPR006207
Domain	CTCK_2	VWF MUC5B SSPOP	6.23e-05	25	58	3	PS01225
Domain	EGF	NID1 LRP1B TNXB NOTCH3 PROC LRP8	8.72e-05	235	58	6	SM00181
Domain	EGF-like_dom	NID1 LRP1B TNXB NOTCH3 PROC LRP8	1.20e-04	249	58	6	IPR000742
Domain	EGF_CA	NID1 LRP1B NOTCH3 LRP8	1.47e-04	86	58	4	PF07645
Domain	EGF-like_CS	NID1 LRP1B TNXB NOTCH3 PROC LRP8	1.55e-04	261	58	6	IPR013032
Domain	VWFC_1	VWF MUC5B SSPOP	1.89e-04	36	58	3	PS01208
Domain	VWC	VWF MUC5B SSPOP	2.22e-04	38	58	3	SM00214
Domain	VWFC_2	VWF MUC5B SSPOP	2.22e-04	38	58	3	PS50184
Domain	-	NID1 LRP1B LRP8	2.40e-04	39	58	3	2.120.10.30
Domain	LDLR_class-A_CS	LRP1B SSPOP LRP8	2.59e-04	40	58	3	IPR023415
Domain	VWF_dom	VWF MUC5B SSPOP	2.99e-04	42	58	3	IPR001007
Domain	BTK	RASA4 RASA4B	3.36e-04	9	58	2	SM00107
Domain	Znf_Btk_motif	RASA4 RASA4B	3.36e-04	9	58	2	IPR001562
Domain	BTK	RASA4 RASA4B	3.36e-04	9	58	2	PF00779
Domain	ZF_BTK	RASA4 RASA4B	3.36e-04	9	58	2	PS51113
Domain	Ldl_recept_a	LRP1B SSPOP LRP8	3.68e-04	45	58	3	PF00057
Domain	-	LRP1B SSPOP LRP8	3.92e-04	46	58	3	4.10.400.10
Domain	6-blade_b-propeller_TolB-like	NID1 LRP1B LRP8	3.92e-04	46	58	3	IPR011042
Domain	LDLRA_1	LRP1B SSPOP LRP8	4.45e-04	48	58	3	PS01209
Domain	LDLRA_2	LRP1B SSPOP LRP8	4.73e-04	49	58	3	PS50068
Domain	LDrepeatLR_classA_rpt	LRP1B SSPOP LRP8	4.73e-04	49	58	3	IPR002172
Domain	LDLa	LRP1B SSPOP LRP8	4.73e-04	49	58	3	SM00192
Domain	-	ABHD15 ACOT1 ACOT6 ACOT4	5.10e-04	119	58	4	3.40.50.1820
Domain	AB_hydrolase	ABHD15 ACOT1 ACOT6 ACOT4	5.10e-04	119	58	4	IPR029058
Domain	RasGAP	RASA4 RASA4B	8.42e-04	14	58	2	SM00323
Domain	RasGAP_CS	RASA4 RASA4B	8.42e-04	14	58	2	IPR023152
Domain	EGF_extracell	LRP1B TNXB NOTCH3	8.58e-04	60	58	3	IPR013111
Domain	EGF_2	LRP1B TNXB NOTCH3	8.58e-04	60	58	3	PF07974
Domain	RasGAP	RASA4 RASA4B	9.70e-04	15	58	2	PF00616
Domain	RAS_GTPASE_ACTIV_1	RASA4 RASA4B	9.70e-04	15	58	2	PS00509
Domain	RAS_GTPASE_ACTIV_2	RASA4 RASA4B	9.70e-04	15	58	2	PS50018
Domain	Glyco_hormone_CN	MUC5B GPHB5	9.70e-04	15	58	2	IPR006208
Domain	Cys_knot	MUC5B GPHB5	9.70e-04	15	58	2	PF00007
Domain	-	RASA4 RASA4B	1.11e-03	16	58	2	1.10.506.10
Domain	-	NTF4 GDF11 GPHB5	1.18e-03	67	58	3	2.10.90.10
Domain	Cystine-knot_cytokine	NTF4 GDF11 GPHB5	1.18e-03	67	58	3	IPR029034
Domain	KAZAL_1	WFIKKN1 HTRA3	1.40e-03	18	58	2	PS00282
Domain	CT	VWF MUC5B	2.10e-03	22	58	2	SM00041
Domain	zf-DHHC	ZDHHC15 ZDHHC17	2.30e-03	23	58	2	PF01529
Domain	Rho_GTPase_activation_prot	RASA4 RASA4B PLXNB1	2.59e-03	88	58	3	IPR008936
Domain	DHHC	ZDHHC15 ZDHHC17	2.72e-03	25	58	2	PS50216
Domain	Znf_DHHC_palmitoyltrfase	ZDHHC15 ZDHHC17	2.72e-03	25	58	2	IPR001594
Domain	cEGF	NID1 LRP1B	2.94e-03	26	58	2	IPR026823
Domain	cEGF	NID1 LRP1B	2.94e-03	26	58	2	PF12662
Pathway	WP_7OXOC_AND_7BETAHC_PATHWAYS	ACOT1 ACOT6 ACOT4	8.43e-05	27	45	3	M40054
Pubmed	Analysis of the mouse and human acyl-CoA thioesterase (ACOT) gene clusters shows that convergent, functional evolution results in a reduced number of human peroxisomal ACOTs.	ACOT1 ACOT6 ACOT4	5.38e-08	5	62	3	16940157
Pubmed	A revised nomenclature for mammalian acyl-CoA thioesterases/hydrolases.	ACOT1 ACOT6 ACOT4	4.50e-07	9	62	3	16103133
Pubmed	CAPRI regulates Ca(2+)-dependent inactivation of the Ras-MAPK pathway.	RASA4 RASA4B	3.13e-06	2	62	2	11448776
Pubmed	The mitochondrial inner membrane protein LETM1 modulates cristae organization through its LETM domain.	LETM1 PINK1	3.13e-06	2	62	2	32139798
Pubmed	Apolipoprotein E Receptor 2 Mediates Activated Protein C-Induced Endothelial Akt Activation and Endothelial Barrier Stabilization.	PROC LRP8	3.13e-06	2	62	2	26800564
Pubmed	PINK1-mediated phosphorylation of LETM1 regulates mitochondrial calcium transport and protects neurons against mitochondrial stress.	LETM1 PINK1	3.13e-06	2	62	2	29123128
Pubmed	An essential function for the calcium-promoted Ras inactivator in Fcgamma receptor-mediated phagocytosis.	RASA4 RASA4B	3.13e-06	2	62	2	16041389
Pubmed	Peroxisome proliferator-induced long chain acyl-CoA thioesterases comprise a highly conserved novel multi-gene family involved in lipid metabolism.	ACOT1 ACOT4	9.37e-06	3	62	2	10567408
Pubmed	CD28 inhibits T cell adhesion by recruiting CAPRI to the plasma membrane.	RASA4 RASA4B	9.37e-06	3	62	2	25637021
Pubmed	Protein C supports platelet binding and activation under flow: role of glycoprotein Ib and apolipoprotein E receptor 2.	PROC LRP8	9.37e-06	3	62	2	18489431
Pubmed	Associations between genetic variants of KIF5B, FMN1, and MGAT3 in the cadherin pathway and pancreatic cancer risk.	MGAT3 FMN1	9.37e-06	3	62	2	33200553
Pubmed	Polyamines are involved in murine kidney development controlling expression of c-ret, E-cadherin, and Pax2/8 genes.	ODC1 RET	1.87e-05	4	62	2	16138831
Pubmed	Ca2+-dependent monomer and dimer formation switches CAPRI Protein between Ras GTPase-activating protein (GAP) and RapGAP activities.	RASA4 RASA4B	1.87e-05	4	62	2	21460216
Pubmed	GRN, NOTCH3, FN1, and PINK1 expression in eutopic endometrium - potential biomarkers in the detection of endometriosis - a pilot study.	NOTCH3 PINK1	1.87e-05	4	62	2	33029756
Pubmed	Haemostatic changes and acquired activated protein C resistance in normal pregnancy.	VWF PROC	1.87e-05	4	62	2	17890957
Pubmed	Both WFIKKN1 and WFIKKN2 have high affinity for growth and differentiation factors 8 and 11.	WFIKKN1 GDF11	1.87e-05	4	62	2	18596030
Pubmed	Molecular cloning and characterization of two mouse peroxisome proliferator-activated receptor alpha (PPARalpha)-regulated peroxisomal acyl-CoA thioesterases.	ACOT1 ACOT4	1.87e-05	4	62	2	15007068
Pubmed	Polymorphisms in the human high sulfur hair keratin-associated protein 1, KAP1, gene family.	KRTAP1-1 KRTAP1-3	1.87e-05	4	62	2	12228244
Pubmed	Identification of an alternatively spliced variant of Ca2+-promoted Ras inactivator as a possible regulator of RANKL shedding.	RASA4 RASA4B	1.87e-05	4	62	2	16234249
Pubmed	Palmitoylation and membrane interactions of the neuroprotective chaperone cysteine-string protein.	ZDHHC15 ZDHHC17	3.12e-05	5	62	2	18596047
Pubmed	Activated protein C ligation of ApoER2 (LRP8) causes Dab1-dependent signaling in U937 cells.	PROC LRP8	3.12e-05	5	62	2	19116273
Pubmed	Molecular basis of fatty acid selectivity in the zDHHC family of S-acyltransferases revealed by click chemistry.	ZDHHC15 ZDHHC17	3.12e-05	5	62	2	28167757
Pubmed	Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins.	RET LRP1B NOTCH3 LRP8	3.28e-05	101	62	4	23382219
Pubmed	Novel protein interactions with endoglin and activin receptor-like kinase 1: potential role in vascular networks.	FBXO24 RASA4 RASA4B ACVRL1	7.79e-05	126	62	4	24319055
Pubmed	Preferential expression of connexin37 and connexin40 in the endothelium of the portal veins during mouse liver development.	VWF NID1	8.69e-05	8	62	2	16505993
Pubmed	The cellular and molecular basis of direction selectivity of Aδ-LTMRs.	NTF4 RET	8.69e-05	8	62	2	25525881
Pubmed	Comparative genome mapping in the sequence-based era: early experience with human chromosome 7.	RASA4 RASA4B	8.69e-05	8	62	2	10810084
Pubmed	WFIKKN1 and WFIKKN2 bind growth factors TGFβ1, BMP2 and BMP4 but do not inhibit their signalling activity.	WFIKKN1 GDF11	1.12e-04	9	62	2	21054789
Pubmed	TGFbeta superfamily signals are required for morphogenesis of the kidney mesenchyme progenitor population.	RET ACVRL1 GDF11	1.32e-04	55	62	3	15342483
Pubmed	Regulation of metanephric kidney development by growth/differentiation factor 11.	RET GDF11	1.39e-04	10	62	2	12729564
Pubmed	Reelin signaling is necessary for a specific step in the migration of hindbrain efferent neurons.	RET LRP8	1.70e-04	11	62	2	15703280
Pubmed	The malformed kidney: disruption of glomerular and tubular development.	FMN1 RET	1.70e-04	11	62	2	10668924
Pubmed	YAC complementation shows a requirement for Wt1 in the development of epicardium, adrenal gland and throughout nephrogenesis.	RET TNXB	2.04e-04	12	62	2	10101119
Pubmed	Proteomics analysis of cardiac extracellular matrix remodeling in a porcine model of ischemia/reperfusion injury.	NID1 SSPOP TNXB	2.08e-04	64	62	3	22261194
Pubmed	Defining the membrane proteome of NK cells.	ABHD15 CAD ABCF3 GTF3C1 PRIM1 AGFG2 DGKA CORO7 LRP8	2.16e-04	1168	62	9	19946888
Pubmed	Inhibition of notch1-dependent cardiomyogenesis leads to a dilated myopathy in the neonatal heart.	VWF NOTCH3	2.41e-04	13	62	2	20558824
Pubmed	Cytoplasmic plaque formation in hemidesmosome development is dependent on SoxF transcription factor function.	VWF NID1	2.41e-04	13	62	2	22962592
Pubmed	Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.	VWF NID1 SSPOP TNXB	2.75e-04	175	62	4	28071719
Pubmed	The characterization of mice with a targeted combined deficiency of protein c and factor XI.	VWF PROC	3.23e-04	15	62	2	11159184
Pubmed	Regulation of GDF-11 and myostatin activity by GASP-1 and GASP-2.	WFIKKN1 GDF11	3.23e-04	15	62	2	24019467
Pubmed	Analysis of substrate specificity of human DHHC protein acyltransferases using a yeast expression system.	ZDHHC15 ZDHHC17	3.69e-04	16	62	2	23034182
Pubmed	Identification of PSD-95 palmitoylating enzymes.	ZDHHC15 ZDHHC17	4.18e-04	17	62	2	15603741
Pubmed	Integrin-linked kinase is an adaptor with essential functions during mouse development.	NID1 RET	4.70e-04	18	62	2	19829382
Pubmed	The ECM protein nephronectin promotes kidney development via integrin alpha8beta1-mediated stimulation of Gdnf expression.	RET GDF11	4.70e-04	18	62	2	17537792
Pubmed	Transcriptional regulatory network of SOX4 during myoblast differentiation.	RP1L1 PLXNB1	5.24e-04	19	62	2	25969425
Pubmed	Intracellular localization and tissue-specific distribution of human and yeast DHHC cysteine-rich domain-containing proteins.	ZDHHC15 ZDHHC17	5.82e-04	20	62	2	16647879
Pubmed	A dual-strategy expression screen for candidate connectivity labels in the developing thalamus.	RET PLXNB1 LRP8	5.86e-04	91	62	3	28558017
Pubmed	MESD is essential for apical localization of megalin/LRP2 in the visceral endoderm.	LRP1B LRP8	6.42e-04	21	62	2	21337463
Pubmed	A role for the primary cilium in Notch signaling and epidermal differentiation during skin development.	NID1 NOTCH3	6.42e-04	21	62	2	21703454
Pubmed	Sema4C-Plexin B2 signalling modulates ureteric branching in developing kidney.	RET PLXNB1	7.72e-04	23	62	2	21035938
Pubmed	Fras1, a basement membrane-associated protein mutated in Fraser syndrome, mediates both the initiation of the mammalian kidney and the integrity of renal glomeruli.	RET GDF11	7.72e-04	23	62	2	18787044
Pubmed	Renal collecting system growth and function depend upon embryonic γ1 laminin expression.	NID1 RET	7.72e-04	23	62	2	21903675
Pubmed	The Krüppel-like zinc finger protein GLIS3 transactivates neurogenin 3 for proper fetal pancreatic islet differentiation in mice.	GDF11 NOTCH3	9.14e-04	25	62	2	21786021
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	CAD MGAT3 VWF SBF1 ATP9A CORO7 AQP4 ELFN2 LETM1	9.37e-04	1431	62	9	37142655
Pubmed	The TGFβ type I receptor TGFβRI functions as an inhibitor of BMP signaling in cartilage.	ACVRL1 GDF11	9.89e-04	26	62	2	31311865
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	GTF3C1 SBF1 DGKA ZDHHC17 LETM1 PLXNB1	1.05e-03	650	62	6	38777146
Pubmed	Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System.	NTF4 RET PLXNB1 LRP8	1.06e-03	251	62	4	29031500
Pubmed	Conditionals by inversion provide a universal method for the generation of conditional alleles.	RET GDF11	1.07e-03	27	62	2	23918385
Pubmed	Notch3 interactome analysis identified WWP2 as a negative regulator of Notch3 signaling in ovarian cancer.	RET NOTCH3	1.15e-03	28	62	2	25356737
Pubmed	Cross-disorder genome-wide analyses suggest a complex genetic relationship between Tourette's syndrome and OCD.	FAM201A ATP9A	1.15e-03	28	62	2	25158072
Pubmed	Mutations in Hcfc1 and Ronin result in an inborn error of cobalamin metabolism and ribosomopathy.	AQP4 LETM1	1.23e-03	29	62	2	35013307
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	GTF3C1 NID1 ATP9A USP48 LRP1B PLXNB1 NOTCH3 LRP8	1.28e-03	1201	62	8	35696571
Pubmed	TBX1 is required for normal stria vascularis and semicircular canal development.	NID1 NOTCH3	1.41e-03	31	62	2	31550482
Pubmed	ΔNp63 knockout mice reveal its indispensable role as a master regulator of epithelial development and differentiation.	NID1 NOTCH3	1.41e-03	31	62	2	22274697
Pubmed	Early embryonic expression of murine coagulation system components.	VWF PROC	1.69e-03	34	62	2	11154109
Interaction	CRYBA4 interactions	GTF3C1 SBF1 USP48 DDB2	3.03e-06	35	58	4	int:CRYBA4
Cytoband	Ensembl 112 genes in cytogenetic band chr7q22	FBXO24 RASA4 AGFG2 RASA4B	2.26e-04	219	62	4	chr7q22
Cytoband	14q24.3	ACOT1 ACOT6 ACOT4	2.79e-04	93	62	3	14q24.3
Cytoband	7q22	FBXO24 RASA4	1.22e-03	38	62	2	7q22
Cytoband	1q42.13	TRIM11 OBSCN-AS1	2.03e-03	49	62	2	1q42.13
Cytoband	Ensembl 112 genes in cytogenetic band chr14q24	ACOT1 ACOT6 ACOT4	2.55e-03	200	62	3	chr14q24
Cytoband	Ensembl 112 genes in cytogenetic band chr12q13	PRIM1 DGKA ACVRL1 GDF11	2.60e-03	423	62	4	chr12q13
Cytoband	Ensembl 112 genes in cytogenetic band chr4p16	HTRA3 CPZ LETM1	3.42e-03	222	62	3	chr4p16
Cytoband	Ensembl 112 genes in cytogenetic band chr1q42	TRIM11 NID1 OBSCN-AS1	4.25e-03	240	62	3	chr1q42
Cytoband	4p16.1	HTRA3 CPZ	5.17e-03	79	62	2	4p16.1
Cytoband	22q13.1	MGAT3 ELFN2	5.96e-03	85	62	2	22q13.1
GeneFamily	Acyl-CoA thioesterases	ACOT1 ACOT6 ACOT4	2.36e-06	10	50	3	41
GeneFamily	Pleckstrin homology domain containing\|SH2 domain containing\|C2 and RasGAP domain containing	RASA4 RASA4B	3.33e-04	10	50	2	830
GeneFamily	Low density lipoprotein receptors	LRP1B LRP8	5.73e-04	13	50	2	634
GeneFamily	Zinc fingers DHHC-type\|Ankyrin repeat domain containing	ZDHHC15 ZDHHC17	1.99e-03	24	50	2	76
Coexpression	NABA_MATRISOME	VWF NTF4 WFIKKN1 NID1 HTRA3 MUC5B SSPOP ELFN2 GDF11 TNXB PLXNB1	2.17e-05	1008	62	11	MM17056
Coexpression	NABA_MATRISOME	VWF NTF4 WFIKKN1 NID1 HTRA3 MUC5B SSPOP ELFN2 GDF11 TNXB PLXNB1	2.55e-05	1026	62	11	M5889
ToppCell	Club-club-8\|World / Class top	MGAT3 NID1 MUC5B TNXB PROC	5.50e-06	182	62	5	8111d917e588008d947021460ddf8f1e7ae1337a
ToppCell	facs-Trachea-3m-Epithelial-airway_epithelial-respiratory_basal_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MGAT3 MUC5B RNF39 AQP4 PLXNB1	6.44e-06	188	62	5	8ffb5394f7b00ea483a5fe4df894d22fda935e5c
ToppCell	facs-Trachea-3m-Epithelial-airway_epithelial-respiratory_basal_cell-basal_epithelial_cell_of_trachea\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MGAT3 MUC5B RNF39 AQP4 PLXNB1	6.44e-06	188	62	5	137ed9958044fab7a13648affb469585d1c48cf6
ToppCell	facs-Lung-18m-Epithelial-airway_epithelial-respiratory_basal_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CNKSR1 MGAT3 NTF4 AQP4 PLXNB1	6.78e-06	190	62	5	47e07ea22733306d8885ee9e5f0b033e2f5e2afb
ToppCell	facs-Lung-18m-Epithelial-airway_epithelial-respiratory_basal_cell-basal_epithelial_cell_of_bronchioalveolar_tree\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CNKSR1 MGAT3 NTF4 AQP4 PLXNB1	6.78e-06	190	62	5	261b8afddfdcba4f70b50df126cef7ad00a0aae0
ToppCell	facs-Heart-LV-3m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NID1 HTRA3 RET TNXB NOTCH3	6.96e-06	191	62	5	b7a57691a4742070cee640e285c1f4d0da95baf1
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Astrocyte-Astrocyte-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ACOT1 ACOT6 AQP4 LRP1B PLXNB1	8.70e-06	200	62	5	07d942803360e1a1e8e131d6e31c726dd0db1a0b
ToppCell	Tracheal-10x3prime_v2-Stromal-Peri/Epineurial_-NAF_epineurial\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	CAD SBF1 PRIM1 NID1 TNXB	8.70e-06	200	62	5	24e13b6d9d2d8b29df1f02544ea9c50084d9e75c
ToppCell	Substantia_nigra-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Mgp_(Mgp)-\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	FBXO24 HTRA3 CPZ TNXB	1.36e-05	104	62	4	11d91471b6c4fa6b00a91d9fd4db72ee60d1f801
ToppCell	Substantia_nigra-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	FBXO24 HTRA3 CPZ TNXB	1.36e-05	104	62	4	424a58b04c8b5108b70f15d8353c8e4b9db1e730
ToppCell	Substantia_nigra-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Mgp_(Mgp)\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	FBXO24 HTRA3 CPZ TNXB	1.36e-05	104	62	4	9b05ae514437eb0c8b1b23607ae8cbc371ffa85b
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-24m-Macroglial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FMN1 PELI3 LRP1B SSPOP	4.12e-05	138	62	4	c1a46fbf1beffa12c3d1b78361e0613e2e9e2d13
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Mesenchymal-nan\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBXO24 MGAT3 PLXNB1 NOTCH3	4.86e-05	144	62	4	121853910eeea1ea0642b3cc99f9200015480368
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-24m-Macroglial-oligodendrocyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FMN1 PELI3 LRP1B SSPOP	5.70e-05	150	62	4	afd651c654e715414eff64cf3a37378d057a56a2
ToppCell	PBMC-Severe-cDC_4\|Severe / Compartment, Disease Groups and Clusters	PELI3 RTL10 RASA4B LRP8	7.32e-05	160	62	4	4dac64e58d9366c399f3d830848ccb720d400be7
ToppCell	droplet-Kidney-KIDNEY-30m-Epithelial-Epcam____brush_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACOT1 ACOT4 AQP4 PROC	7.68e-05	162	62	4	de0fde4310a56dc96bfc134c44d104993526d9bc
ToppCell	368C-Myeloid-Dendritic-pDC\|368C / Donor, Lineage, Cell class and subclass (all cells)	ABHD15 RASA4B PROC LRP8	8.64e-05	167	62	4	1e2fc1637769405a61f4c7e44945712a1888a299
ToppCell	droplet-Kidney-nan-3m-Epithelial-Epcam____brush_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACOT1 AQP4 SSPOP PROC	8.64e-05	167	62	4	40d102e01ccbc7262d00fafd59ca5234909009cb
ToppCell	droplet-Kidney-KIDNEY-30m-Epithelial-brush_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GCDH ACOT1 AQP4 PROC	8.84e-05	168	62	4	b14fd50232887b6dca1f39014d43c6f66e5c3b5c
ToppCell	Transplant_Alveoli_and_parenchyma-Epithelial-Basal_1\|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X	NTF4 ZNF764 MUC5B GDF11	9.25e-05	170	62	4	aabe993c9f337b1caaeb0e64626a3920579c41b7
ToppCell	droplet-Kidney-nan-21m-Epithelial-brush_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACOT1 AQP4 PROC LRP8	9.46e-05	171	62	4	007f148f4611ea1826edfa9f91ced36541ad9f5a
ToppCell	droplet-Kidney-nan-21m-Epithelial-Epcam____brush_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACOT1 AQP4 PROC LRP8	9.46e-05	171	62	4	8e7223ba447947cdf4e1c82a52fd90439cf3d8f6
ToppCell	Transplant_Alveoli_and_parenchyma-Epithelial-Basal_1\|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X	NTF4 ZNF764 MUC5B GDF11	9.68e-05	172	62	4	b66dbfff5e4f53ca8ece91ff9c5dc66a71f07c63
ToppCell	droplet-Thymus-nan-21m-Lymphocytic-Double_negative_thymocyte,_DN3_(Cd8-,_Cd4-),_some_express_pre_TCR_alpha\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABHD15 ACOT6 ELFN2 NOTCH3	1.01e-04	174	62	4	a9f34d1237f335d27c5560ff514368f4709f9144
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DGKA PLXNB1 NOTCH3 LRP8	1.01e-04	174	62	4	207aa0118633cbe9a65839bbb1bb3ba9f8118ad2
ToppCell	droplet-Lung-21m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l21\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GCDH MUC5B RET DDB2	1.06e-04	176	62	4	91ad2c34144f72283ca112fd3b3784f2f6259f65
ToppCell	droplet-Thymus-nan-21m-Lymphocytic-DN3_thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABHD15 ACOT6 ELFN2 NOTCH3	1.06e-04	176	62	4	d43d9e86c4d4fa1e88fbf2b899ac7143717aac90
ToppCell	5'-GW_trimst-2-LymphNode-Endothelial-blood_vessel_EC-Mature_venous_EC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	VWF RASA4 RASA4B ACVRL1	1.10e-04	178	62	4	aa44851653d276226b922ee14dd1fc8d1a844cdf
ToppCell	facs-Lung-3m-Epithelial-airway_epithelial-respiratory_basal_cell-basal_epithelial_cell_of_bronchioalveolar_tree\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MGAT3 NTF4 MUC5B AQP4	1.10e-04	178	62	4	b89c4d015b44bf538aa39969ef8778877c8023f1
ToppCell	facs-Lung-3m-Epithelial-airway_epithelial-respiratory_basal_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MGAT3 NTF4 MUC5B AQP4	1.10e-04	178	62	4	fb8f8d95f6b08378fb42c4076ee040276faa296f
ToppCell	Endothelial\|World / shred by cell class for turbinate	VWF NID1 ACVRL1 TNXB	1.13e-04	179	62	4	052b2681974be00efb8503fa4e2c85d91d5ebd06
ToppCell	moderate-Myeloid-pDC\|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	ABHD15 RET ZDHHC17 PROC	1.15e-04	180	62	4	a0751ad5e42a21cb107d900abfa9ee967a0069fc
ToppCell	3'-Pediatric_IBD-SmallIntestine-Hematopoietic-Myeloid-pDC\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ABHD15 ZDHHC17 ELFN2 PROC	1.20e-04	182	62	4	02c0824373a0ecebc922d4ca848ace9d570722c4
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NID1 HTRA3 CPZ TNXB	1.23e-04	183	62	4	06a68fa2be36448064f4668be24a5b85ad85c6e8
ToppCell	facs-Lung-EPCAM-3m-Epithelial-Basal\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBXO24 MGAT3 NTF4 AQP4	1.23e-04	183	62	4	ecac1cfaff7553a60305b34d6cede6973ffb5430
ToppCell	facs-Lung-EPCAM-3m-Epithelial-respiratory_basal_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBXO24 MGAT3 NTF4 AQP4	1.23e-04	183	62	4	f6ebfd7f61e912f92bd07313cc213a171747ac03
ToppCell	facs-Heart-LV-24m-Myeloid-macrophage\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CNKSR1 FMN1 RNF39 PROC	1.28e-04	185	62	4	a835f821a5e6568d648df831ec4c2d0048d67093
ToppCell	facs-Heart-LV-24m-Myeloid-macrophage\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CNKSR1 FMN1 RNF39 PROC	1.28e-04	185	62	4	386b08bcb304db543e3c5ff75f85e99bf0c592df
ToppCell	droplet-Kidney-KIDNEY-1m-Mesenchymal-Stroma____fibroblast\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NID1 HTRA3 CPZ TNXB	1.28e-04	185	62	4	785c55d39909fac74415f24427979691e7e694e6
ToppCell	droplet-Kidney-KIDNEY-1m-Mesenchymal\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NID1 HTRA3 CPZ TNXB	1.28e-04	185	62	4	97a1dcacbc48dc3f41c26fbb59af35c935f894d4
ToppCell	facs-Trachea-3m-Epithelial-airway_epithelial\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MGAT3 MUC5B AQP4 PLXNB1	1.31e-04	186	62	4	37b93ebd64ebbd08193a746e5bc9b350c2570733
ToppCell	droplet-Kidney-KIDNEY-1m-Mesenchymal-fibroblast\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NID1 HTRA3 CPZ TNXB	1.31e-04	186	62	4	94d577dbb6bfacf50632e1fe8af041b35a1e6b23
ToppCell	droplet-Fat-SCAT-30m-Epithelial\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CNKSR1 MUC5B ATP9A PLXNB1	1.34e-04	187	62	4	5fada3c5a58c1890029ccbfff2608b33f8cd2df7
ToppCell	droplet-Fat-SCAT-30m-Epithelial-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CNKSR1 MUC5B ATP9A PLXNB1	1.34e-04	187	62	4	766e808138fc2cd623c2e6d57fcb5c7378da0e03
ToppCell	droplet-Fat-SCAT-30m-Epithelial-epithelial_cell\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CNKSR1 MUC5B ATP9A PLXNB1	1.34e-04	187	62	4	f49d06600060deeb2fc1b1da5b93496535f20104
ToppCell	facs-Trachea-nan-3m-Epithelial-basal_epithelial_cell_of_tracheobronchial_tree\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CNKSR1 MGAT3 AQP4 PLXNB1	1.34e-04	187	62	4	fe9fc21192ede2eea61f419d20ccda254569d0a6
ToppCell	facs-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l20-1\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NID1 HTRA3 RET TNXB	1.36e-04	188	62	4	aa516273cdde53c8c0295f06830972388f890c97
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NID1 HTRA3 CPZ TNXB	1.36e-04	188	62	4	e18065bbc26d6f3774fd1f478fb41d8fb555fa26
ToppCell	facs-Lung-EPCAM-18m-Epithelial-Basal\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MGAT3 NTF4 AQP4 PLXNB1	1.39e-04	189	62	4	783c1db856f2defe6f3b8748dd0bc29a8102f6d1
ToppCell	Fibroblast-C\|World / shred on cell class and cell subclass (v4)	NID1 HTRA3 CPZ TNXB	1.39e-04	189	62	4	58e0400fbab5a0755504275aef5cf7986149abab
ToppCell	droplet-Lung-LUNG-1m-Mesenchymal-adventitial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NID1 HTRA3 CPZ TNXB	1.39e-04	189	62	4	f0a2d4ef9896d764971ebbc6952510c128bb76e8
ToppCell	facs-Trachea-24m-Epithelial-airway_epithelial-respiratory_basal_cell-basal_epithelial_cell_of_trachea\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MGAT3 MUC5B AQP4 PLXNB1	1.39e-04	189	62	4	ee15b4fb3a1cfda80bcf210a23f04f242594015e
ToppCell	facs-Trachea-24m-Epithelial-airway_epithelial-respiratory_basal_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MGAT3 MUC5B AQP4 PLXNB1	1.39e-04	189	62	4	dc6f6fae84347d145bea71b49eaeeb3028e9c4ae
ToppCell	droplet-Lung-LUNG-1m-Mesenchymal-Adventitial_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NID1 HTRA3 CPZ TNXB	1.39e-04	189	62	4	378f26f751ab4b470948c35dd8347de72dd12ff7
ToppCell	facs-Lung-EPCAM-18m-Epithelial-respiratory_basal_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MGAT3 NTF4 AQP4 PLXNB1	1.39e-04	189	62	4	88b72fafbe58463543e0818f27f3dd9e5b4d34d2
ToppCell	droplet-Kidney-nan-3m-Mesenchymal-fibroblast\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NID1 HTRA3 CPZ TNXB	1.42e-04	190	62	4	f61e21d53f2f7804ac6e40ab6c7f69838aa94d6a
ToppCell	droplet-Kidney-nan-3m-Mesenchymal\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NID1 HTRA3 CPZ TNXB	1.42e-04	190	62	4	2abeb013bb83c578e67dcb985ba44ca63134950b
ToppCell	PND01-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NID1 HTRA3 CPZ TNXB	1.42e-04	190	62	4	947807863a9b247c301c6cf63d6fd5a2c8018e66
ToppCell	facs-Trachea-24m-Epithelial-airway_epithelial\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MGAT3 MUC5B AQP4 PLXNB1	1.42e-04	190	62	4	576c45a30a4808b47433bc6c2c41396135556c40
ToppCell	(7)_Epithelial-G_(Club-Clara_cells)\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	NTF4 MUC5B RNF39 NOTCH3	1.42e-04	190	62	4	593fd1451038b155826a48de4caa38f44406d0b9
ToppCell	(011)_pDC\|World / immune cells in Peripheral Blood (logTPM normalization)	ABHD15 RET ZDHHC17 PROC	1.45e-04	191	62	4	d82ac4f6d9863734e09bf3cb71c1354a49b66b4f
ToppCell	droplet-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FBXO24 HTRA3 CPZ TNXB	1.45e-04	191	62	4	b51e0f5d1b93f526160c904e9091313a5364f3a7
ToppCell	PND01-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NID1 HTRA3 CPZ TNXB	1.45e-04	191	62	4	db4943dd19207663fb9e27f8940fa4b06a933625
ToppCell	PND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NID1 HTRA3 CPZ TNXB	1.45e-04	191	62	4	9f478f36a0b895e607e3bb77fa0f9f03cc0f33fc
ToppCell	droplet-Kidney-nan-3m-Mesenchymal-Stroma____fibroblast\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NID1 HTRA3 CPZ TNXB	1.45e-04	191	62	4	d1205aab0937f2becfcd239610e9b78fb8a0c886
ToppCell	droplet-Kidney-KIDNEY-30m-Mesenchymal-fibroblast\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NID1 HTRA3 CPZ TNXB	1.48e-04	192	62	4	853a930e0641ffb50cbb4cef5837c70d75c3fc39
ToppCell	facs-Heart-LV-3m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NID1 HTRA3 RET TNXB	1.48e-04	192	62	4	671d4e1eee5aba03c43dbc98f4b51ce42b3df5d5
ToppCell	facs-Lung-nan-3m-Mesenchymal-Adventitial_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NID1 HTRA3 CPZ TNXB	1.48e-04	192	62	4	a2c31390da4962bda9a936470b0b68fa1f5d47d1
ToppCell	facs-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l1\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NID1 HTRA3 CPZ TNXB	1.48e-04	192	62	4	7b48df661f61ce494bf6f0b9a74b0422e29c24bf
ToppCell	facs-Lung-nan-3m-Mesenchymal-adventitial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NID1 HTRA3 CPZ TNXB	1.48e-04	192	62	4	eeab1cef7c36ae824381952c5b2c982368c379fd
ToppCell	droplet-Kidney-KIDNEY-30m-Mesenchymal-Stroma____fibroblast\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NID1 HTRA3 CPZ TNXB	1.48e-04	192	62	4	d2c03490c5e835d0f0a732803093c64b8d4b4029
ToppCell	facs-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NID1 HTRA3 CPZ TNXB	1.48e-04	192	62	4	32acd89617934016cd135d2cc797e8e79ae1b37f
ToppCell	facs-Heart-LV-3m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NID1 HTRA3 RET TNXB	1.48e-04	192	62	4	840a34c1b82d218be999ab5e1bcafd6370d7a4b1
ToppCell	droplet-Kidney-KIDNEY-30m-Mesenchymal\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NID1 HTRA3 CPZ TNXB	1.48e-04	192	62	4	49281626ecad0456fdbded2378b7028d7b589686
ToppCell	facs-Lung-EPCAM-18m-Epithelial\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MGAT3 NTF4 AQP4 PLXNB1	1.48e-04	192	62	4	12096302a3a4d26e21ca04357aa557143f482155
ToppCell	droplet-Fat-Scat-18m-Mesenchymal-Cd34+\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NID1 HTRA3 CPZ TNXB	1.51e-04	193	62	4	316ebdf15f75d88c348f909b643fcd315364ca84
ToppCell	droplet-Fat-Scat-18m-Mesenchymal-mesenchymal_stem_cell_of_adipose\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NID1 HTRA3 CPZ TNXB	1.51e-04	193	62	4	1afdd3f7d703f4204a2cbfe40e135ac7b09213f7
ToppCell	facs-Lung-18m-Epithelial\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CNKSR1 NTF4 AQP4 PLXNB1	1.51e-04	193	62	4	8e934f127bc763e905c788beabfa867bd559b682
ToppCell	droplet-Fat-Scat-18m-Mesenchymal\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NID1 HTRA3 CPZ TNXB	1.51e-04	193	62	4	8dc6db335678f3a5cfd36026ad811fed8d9cb4bc
ToppCell	PND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NID1 HTRA3 CPZ TNXB	1.51e-04	193	62	4	051f61156b0e2e95292b2d8377faf3190b50f264
ToppCell	facs-BAT-Fat-3m-Mesenchymal-mesenchymal_progenitor\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NID1 HTRA3 CPZ TNXB	1.54e-04	194	62	4	da45811ba07d746e7cba7ed78882b5d98ac7397d
ToppCell	facs-BAT-Fat-3m-Mesenchymal\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NID1 HTRA3 CPZ TNXB	1.54e-04	194	62	4	76b8512fd92014b3ecc42b0a20d6d1df074cba2c
ToppCell	facs-BAT-Fat-3m-Mesenchymal-mesenchymal_stem_cell_of_adipose\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NID1 HTRA3 CPZ TNXB	1.54e-04	194	62	4	ef0fa9daecd3bf43c6cf56345928cacdbee19779
ToppCell	facs-Lung-18m-Epithelial-airway_epithelial\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CNKSR1 MGAT3 NTF4 AQP4	1.57e-04	195	62	4	ed052c6d3dc104b02e34b645abfdee477af050c6
ToppCell	5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_pulmonary-EC_venous_pulmonary_L.2.2.2.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	VWF RASA4 RASA4B ACVRL1	1.57e-04	195	62	4	81a98ebb0d43f416f9a8bba580531dc0cfea8f74
ToppCell	Tracheal-10x5prime-Epithelial-Epi_airway_secretory-Secretory_Club\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	MUC5B AQP4 ELFN2 NOTCH3	1.63e-04	197	62	4	01e9505d947e5a5f005d1eab96301f84fc194809
ToppCell	distal-1-Hematologic-Plasmacytoid_Dendritic\|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ABHD15 RET LRP1B PROC	1.63e-04	197	62	4	166d47359df9279ea8c3946f10bd3d4b88c95857
ToppCell	5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-vein_endothelial_cell\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	VWF RASA4 ACVRL1 TNXB	1.63e-04	197	62	4	0542badae77d2f606c13cfaf361319495c354351
ToppCell	5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_pulmonary\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	VWF RASA4 ACVRL1 TNXB	1.63e-04	197	62	4	a6a64581699cfcb9607b288976fa3b09648725b7
ToppCell	3'-Adult-LymphNode-Mesenchymal-fibroblastic-mLN_Stroma_(FMO2+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NID1 HTRA3 LRP1B TNXB	1.66e-04	198	62	4	abac765c4f6864bdb1700bc546c3b9771edc25c3
ToppCell	droplet-Limb_Muscle-MUSCLE-1m-Mesenchymal-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NID1 HTRA3 RET TNXB	1.66e-04	198	62	4	5e70246a9ce199cb2fb5379912b8ab59456219e4
ToppCell	Non-neuronal-Postmitotic-Mural-Mural\|World / Primary Cells by Cluster	VWF NID1 ACVRL1 NOTCH3	1.66e-04	198	62	4	9fc1035ea447a4551a66944c869c4671e17cec61
ToppCell	Non-neuronal-Postmitotic-Mural\|World / Primary Cells by Cluster	VWF NID1 ACVRL1 NOTCH3	1.66e-04	198	62	4	dd38840a96171f58da243daa22b013e15a81db4a
ToppCell	droplet-Limb_Muscle-MUSCLE-1m-Mesenchymal-mesenchymal_stem_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NID1 HTRA3 CPZ TNXB	1.66e-04	198	62	4	1b90d632e59c3c47b936e829cceeb0334f05f34f
ToppCell	3'-Adult-LymphNode-Mesenchymal-fibroblastic\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NID1 HTRA3 LRP1B TNXB	1.66e-04	198	62	4	ff57addcbdd53e5d2d0c80ec76b5eab3b3a67ca2
ToppCell	Parenchymal-10x5prime-Stromal-Pericyte-Muscle_pericyte_systemic\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	FBXO24 NID1 RET NOTCH3	1.66e-04	198	62	4	0dc5806714fb3d3983e9d19fa7a108e93a8090ed
ToppCell	Non-neuronal-Postmitotic-Mural-Mural-18\|World / Primary Cells by Cluster	VWF NID1 ACVRL1 NOTCH3	1.66e-04	198	62	4	21efb7bcd24f24d20791b34e75d6f9d46a129481
ToppCell	3'-Adult-LymphNode-Mesenchymal\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NID1 HTRA3 LRP1B TNXB	1.66e-04	198	62	4	698166b4ca173176ed563af6a1efc8c7d0a18e0b
ToppCell	Sigmoid-(1)_T_cell-(14)_Tcm\|Sigmoid / shred on region, Cell_type, and subtype	ZDHHC15 DGKA RASA4B FBXO17	1.69e-04	199	62	4	ec454fa22fb7f50a947bdf4c4bb6f0ba13f62b4c
ToppCell	Bronchial-10x5prime-Epithelial-Epi_airway_secretory-Secretory_Club\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	MUC5B RNF39 AQP4 NOTCH3	1.69e-04	199	62	4	2b357cc08c425a58d45aa6c086101c8fff53e218
Computational	Trachea genes.	CNKSR1 VWF DGKA MUC5B ATP9A TNXB NOTCH3	1.43e-04	415	31	7	MODULE_6
Disease	cardiovascular event measurement, response to placebo	ACOT6 ACOT4	1.10e-05	3	57	2	EFO_0006919, EFO_0008344
Disease	osteonecrosis (is_marker_for)	VWF PROC	2.19e-05	4	57	2	DOID:10159 (is_marker_for)
Disease	X-16935 measurement	ACOT6 ACOT4	7.65e-05	7	57	2	EFO_0800763
Disease	X-24747 measurement	ACOT6 ACOT4	1.02e-04	8	57	2	EFO_0022135
Disease	response to darapladib, cardiovascular event measurement	ACOT6 ACOT4	1.02e-04	8	57	2	EFO_0006919, EFO_0008395
Disease	X-17653 measurement	ACOT6 ACOT4	1.31e-04	9	57	2	EFO_0800783
Disease	Hirschsprung's disease (implicated_via_orthology)	RET PINK1	2.39e-04	12	57	2	DOID:10487 (implicated_via_orthology)
Disease	undecenoylcarnitine (C11:1) measurement	ACOT6 ACOT4	2.82e-04	13	57	2	EFO_0800588
Disease	Nerve Degeneration	NTF4 PINK1 LRP8	5.63e-04	83	57	3	C0027746
Disease	arginine measurement	PRIM1 GCDH	9.04e-04	23	57	2	EFO_0020990
Disease	factor VIII measurement, von Willebrand factor measurement	MGAT3 VWF	1.25e-03	27	57	2	EFO_0004629, EFO_0004630
Disease	pulmonary hypertension (is_implicated_in)	VWF ACVRL1	1.54e-03	30	57	2	DOID:6432 (is_implicated_in)

Protein segments in the cluster

Peptide	Gene	Start	Entry
GRCCWDEPVRIAVRG	ACOT1	11	Q86TX2
TARRWGKCGPLCTRE	AQP4	6	P55087
RLVCRELWVCEGGGV	ABCF3	671	Q9NUQ8
WIERPCCGDTVCVRT	RTL10	46	Q7L3V2
GRCCWDEPLRIAVRG	ACOT6	11	Q3I5F7
CRGAWCTVVLVREEG	ACVRL1	46	P37023
TPCDRCGVRGEQWRI	FAM187A	176	A6NFU0
ALDWVVGPCVRGRRI	ABHD15	136	Q6UXT9
CISPVLRCREWFEAG	ABHD15	261	Q6UXT9
ELCRARGVCSDWRGA	MUC5B	5336	Q9HC84
VWPGARACRLRCSVL	RASA4	126	O43374
GGCRGVDRRHWVSEC	NTF4	156	P34130
VWPGARACRLRCSVL	RASA4B	126	C9J798
RWRGGCEERKDVCIS	FMN1	776	Q68DA7
GVDRCVRACRTWSAP	FHIP1B	561	Q8N612
VLRCGECWRARGLPG	FAM201A	26	Q5SY85
NGRCIPRAWLCDRED	LRP1B	936	Q9NZR2
SRACVPRHWLCDGER	LRP1B	2771	Q9NZR2
GRGARRKWVECVCLP	MGAT3	161	Q09327
GCWALRPECLRIVSR	LETM1	71	O95202
GGRGARIVWVCDGRC	CORO7	681	P57737
CVWCEGERPRCVTRE	PLXNB1	1041	O43157
VVRAWGCAGPCGRAV	PINK1	86	Q9BXM7
CWCVDRDGREVEGTR	NID1	896	P14543
FWGPRCERVARSCRE	NOTCH3	1281	Q9UM47
VWVRGGCESGRCDRC	DGKA	271	P23743
IRWCRPDCRVEGTCL	KRTAP1-1	116	Q07627
IRWCRPDCRVEGTCL	KRTAP1-3	106	Q8IUG1
EWLRCCGGGEARPRT	ATP9A	26	O75110
RRCDSDCLWVGLAGP	DDB2	46	Q92466
EKGERRGQVPCRSVW	SBF1	1541	O95248
CLEEVGWRRCSCAPG	PROC	151	P04070
GRRGVHCWVCDESVR	PRIM1	161	P49642
RCRPVCRAWRDIVDG	FBXO17	41	Q96EF6
GESLECVRGLCRCRW	HTRA3	71	P83110
GCAVLAPRCEGGWVR	CPZ	101	Q66K79
APRCEGGWVRRPCRH	CPZ	106	Q66K79
GGWVRRPCRHICEGL	CPZ	111	Q66K79
LFVVWARCEDGCIRG	GCDH	221	Q92947
RGLRITTDACWGRCE	GPHB5	51	Q86YW7
GCPVCVWRQHSRELR	GDF11	61	O95390
EVCDGEGVWRRICRR	FBXO24	71	O75426
WGPTCDGLDRIVERC	ODC1	356	P11926
DGGGACIPERWVCDR	LRP8	216	Q14114
WTPCRCRGRGPTACR	OBSCN-AS1	141	Q96MR7
RVGERWHGGPCRVCQ	SSPOP	1976	A2VEC9
WREAEALCGGGCREP	SSPOP	4641	A2VEC9
WGCRRERGPQERECP	PELI3	371	Q8N2H9
AVQRWVIGRCLCVPE	SHARPIN	266	Q9H0F6
GRCCWNEPVRIAVRG	ACOT4	11	Q8N9L9
SEVWCRRVRELGGCS	AGFG2	26	O95081
VSCRELGRPDCDGWL	CNKSR1	396	Q969H4
CRECIRRCWGQPEGP	TRIM11	36	Q96F44
RGVRVAWREPGRCEL	VWF	636	P04275
VWGPRPCRVGCREVF	RP1L1	381	Q8IWN7
RGRGRCESGRCMCWP	TNXB	471	P22105
RCLCQRGAEVTVVPW	CAD	191	P27708
SLREGECQWPGCARV	RET	131	P07949
DEGVLEAWGCCRRCR	nan	66	Q3C1V9
RCCGLFRPVIVDWTR	ZDHHC17	601	Q8IUH5
DIWDGQPVCRCRDRC	WFIKKN1	106	Q96NZ8
RGETDVCVPDACRWR	LINC01356	106	Q8N9X3
DCESVCFIGRPWRVV	GTF3C1	1976	Q12789
AYRIWLEPCIRGVCR	USP48	31	Q86UV5
CREEWGCLRPAQRAL	ZNF764	36	Q96H86
QRKGCVRLCPAGAVW	RNF39	321	Q9H2S5
GGLRCCRRVLSWVPV	ZDHHC15	11	Q96MV8
LLCVCRPGAVRADCW	ELFN2	11	Q5R3F8