Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	enzyme-substrate adaptor activity	ZSWIM8 PRAMEF9 ANKRD9 RPTOR PRAMEF11 PRAMEF15 TUT1 PRAMEF4 FBXL19	1.13e-06	95	222	9	GO:0140767
GeneOntologyMolecularFunction	ubiquitin-like ligase-substrate adaptor activity	ZSWIM8 PRAMEF9 ANKRD9 PRAMEF11 PRAMEF15 PRAMEF4 FBXL19	3.58e-05	82	222	7	GO:1990756
GeneOntologyCellularComponent	cullin-RING ubiquitin ligase complex	ZSWIM8 DCAF6 PRAMEF9 DCAF8 ANKRD9 FBXL7 PRAMEF11 PRAMEF15 PRAMEF4 FBXL19	9.06e-05	212	221	10	GO:0031461
GeneOntologyCellularComponent	Cul2-RING ubiquitin ligase complex	ZSWIM8 PRAMEF9 PRAMEF11 PRAMEF15 PRAMEF4	1.35e-04	47	221	5	GO:0031462
Domain	-	LRFN3 LRTM2 LRRC14B FBXL7 GP1BA LRRC8E FLII ISLR2 MXRA5 PRAMEF15 CHADL PRAMEF4 FBXL19 SCRIB LRIT1	5.26e-06	321	216	15	3.80.10.10
Domain	L_dom-like	LRFN3 LRTM2 LRRC14B FBXL7 GP1BA LRRC8E FLII ISLR2 MXRA5 PRAMEF15 CHADL PRAMEF4 FBXL19 SCRIB LRIT1	6.82e-06	328	216	15	IPR032675
Domain	LRR_8	LRFN3 LRTM2 GP1BA LRRC8E FLII ISLR2 MXRA5 CHADL SCRIB LRIT1	3.10e-05	171	216	10	PF13855
Domain	LRR_TYP	LRFN3 LRTM2 GP1BA LRRC8E FLII ISLR2 MXRA5 CHADL SCRIB LRIT1	4.16e-05	177	216	10	SM00369
Domain	Leu-rich_rpt_typical-subtyp	LRFN3 LRTM2 GP1BA LRRC8E FLII ISLR2 MXRA5 CHADL SCRIB LRIT1	4.16e-05	177	216	10	IPR003591
Domain	Leu-rich_rpt	LRFN3 LRTM2 FBXL7 GP1BA LRRC8E FLII ISLR2 MXRA5 CHADL FBXL19 SCRIB LRIT1	7.84e-05	271	216	12	IPR001611
Domain	Cys-rich_flank_reg_C	LRFN3 LRTM2 GP1BA ISLR2 MXRA5 CHADL LRIT1	8.32e-05	90	216	7	IPR000483
Domain	LRRCT	LRFN3 LRTM2 GP1BA ISLR2 MXRA5 CHADL LRIT1	8.32e-05	90	216	7	SM00082
Domain	Tscrpt_reg_Wos2-domain	MYB MYBL1	1.33e-04	2	216	2	IPR012642
Domain	LMSTEN	MYB MYBL1	1.33e-04	2	216	2	PF07988
Domain	LRRNT	LRFN3 LRTM2 GP1BA ISLR2 MXRA5 CHADL LRIT1	1.43e-04	98	216	7	IPR000372
Domain	LRRNT	LRFN3 LRTM2 GP1BA ISLR2 MXRA5 CHADL LRIT1	1.43e-04	98	216	7	SM00013
Domain	EGF-like_dom	RELN ADAM15 PROZ HMCN2 CD248 HYAL1 BCAN TECTA DLL3 CNTNAP2 SORL1	1.59e-04	249	216	11	IPR000742
Domain	LRR_1	LRFN3 LRTM2 FBXL7 LRRC8E FLII ISLR2 CHADL FBXL19 SCRIB LRIT1	2.42e-04	219	216	10	PF00560
Domain	PPR_3	PTCD3 LRPPRC	3.96e-04	3	216	2	PF13812
Domain	Cmyb_C	MYB MYBL1	3.96e-04	3	216	2	PF09316
Domain	C-myb_C	MYB MYBL1	3.96e-04	3	216	2	IPR015395
Domain	EGF	RELN ADAM15 PROZ CD248 HYAL1 BCAN TECTA DLL3 CNTNAP2 SORL1	4.24e-04	235	216	10	SM00181
Domain	EGF_3	RELN ADAM15 PROZ HMCN2 CD248 HYAL1 BCAN DLL3 CNTNAP2 SORL1	4.24e-04	235	216	10	PS50026
Domain	G8_domain	PKHD1 PKHD1L1	7.87e-04	4	216	2	IPR019316
Domain	G8	PKHD1 PKHD1L1	7.87e-04	4	216	2	PS51484
Domain	Gal-3-0_sulfotr	GAL3ST2 GAL3ST4	7.87e-04	4	216	2	PF06990
Domain	G8	PKHD1 PKHD1L1	7.87e-04	4	216	2	SM01225
Domain	G8	PKHD1 PKHD1L1	7.87e-04	4	216	2	PF10162
Domain	Gal-3-0_sulfotransfrase	GAL3ST2 GAL3ST4	7.87e-04	4	216	2	IPR009729
Domain	EGF-like_CS	RELN ADAM15 PROZ HMCN2 CD248 HYAL1 BCAN DLL3 CNTNAP2 SORL1	9.53e-04	261	216	10	IPR013032
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	TRPM4 MGAT4B EPPK1 ANKRD9 PFAS CARD10 COMTD1 MAST2 KIAA2013 C2CD2L PCNX2 URB1 MDN1 RPTOR WDR90 BRAT1 GCN1 LRRC8E FLII ZNF48 EP400 TMEM158 FBXL19 MED13L ZBED3 HDAC7 EML3 KIFC2 ANO8 MROH6 SUGP2 ZNF408 EIF4G1 DISP2 AKAP13 ARRDC2	1.66e-15	1105	226	36	35748872
Pubmed	Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.	SMDT1 KIF1B HMGCS2 COMTD1 CLPB COQ9 LIPT2 AURKAIP1 MTO1 MTARC1 PTCD3 NUDT19 GPD2 PDPR HDDC2 MSRB2 LRPPRC DDX28 ABHD11	1.15e-05	926	226	19	20877624
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	CDKN2A ZSWIM8 DCAF6 ATP7B DCAF8 TSPYL1 GPR108 MAST2 C2CD2L MALT1 HMCN2 RPTOR MTO1 PTCD3 ISLR2 EP400 OBSL1 TRMT2A SUGP2 SCRIB SORL1	1.45e-05	1116	226	21	31753913
Pubmed	Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context.	ATP7B SMDT1 GLYCTK STARD7 HMGCS2 COMTD1 CLPB COQ9 LIPT2 AURKAIP1 MTO1 MTARC1 PTCD3 NUDT19 GDF5-AS1 GPD2 PDPR MSRB2 LRPPRC DDX28 ABHD11	1.88e-05	1136	226	21	34800366
Pubmed	Targeting RICTOR Sensitizes SMAD4-Negative Colon Cancer to Irinotecan.	DCAF8 HMGCS2 MALT1 TFCP2L1 TRIM72 GPD2 CPD EML3	2.83e-05	183	226	8	31932471
Pubmed	Pediatric-type diffuse low-grade glioma with MYB/MYBL1 alteration: report of 2 cases.	MYB MYBL1	4.20e-05	2	226	2	36074655
Pubmed	Glucose restriction can extend normal cell lifespan and impair precancerous cell growth through epigenetic control of hTERT and p16 expression.	CDKN2A TERT	4.20e-05	2	226	2	20019239
Pubmed	DNA binding and transactivation activity of A-myb, a c-myb-related gene.	MYB MYBL1	4.20e-05	2	226	2	7987850
Pubmed	Anti-müllerian hormone and insulin-like 3 levels in healthy normal-weight ovulatory and anovulatory eumenorrheic late adolescent females: potential early biomarkers of ovarian dysfunction?	INSL3 AMH	4.20e-05	2	226	2	26579638
Pubmed	Cyclin-dependent kinase inhibitor p16(INK4a) and telomerase may co-modulate endothelial progenitor cells senescence.	CDKN2A TERT	4.20e-05	2	226	2	18343732
Pubmed	Isomorphic diffuse glioma is a morphologically and molecularly distinct tumour entity with recurrent gene fusions of MYBL1 or MYB and a benign disease course.	MYB MYBL1	4.20e-05	2	226	2	31563982
Pubmed	Breast primary epithelial cells that escape p16-dependent stasis enter a telomere-driven crisis state.	CDKN2A TERT	4.20e-05	2	226	2	26758019
Pubmed	Mutations in 3'-long terminal repeat of HERV-W family in chromosome 7 upregulate syncytin-1 expression in urothelial cell carcinoma of the bladder through interacting with c-Myb.	ERVW-1 MYB	4.20e-05	2	226	2	24013223
Pubmed	Expression of mouse c-myb during embryonic development.	MYB MYBL1	4.20e-05	2	226	2	8570177
Pubmed	Methylation-related silencing of p14ARF gene correlates with telomerase activity and mRNA expression of human telomerase reverse transcriptase in hepatocellular carcinoma.	CDKN2A TERT	4.20e-05	2	226	2	18683194
Pubmed	RAPTOR promotes colorectal cancer proliferation by inducing mTORC1 and upregulating ribosome assembly factor URB1.	URB1 RPTOR	4.20e-05	2	226	2	31886628
Pubmed	Parallel variations of insulin-like peptide 3 (INSL3) and antimüllerian hormone (AMH) in women with the polycystic ovary syndrome according to menstrual cycle pattern.	INSL3 AMH	4.20e-05	2	226	2	23928669
Pubmed	Expression of p16 and hTERT protein is associated with the presence of high-risk human papillomavirus in Bowenoid papulosis.	CDKN2A TERT	4.20e-05	2	226	2	16919029
Pubmed	Physical exercise prevents cellular senescence in circulating leukocytes and in the vessel wall.	NOS3 TERT	4.20e-05	2	226	2	19948976
Pubmed	A single-center study of the clinicopathologic correlates of gliomas with a MYB or MYBL1 alteration.	MYB MYBL1	4.20e-05	2	226	2	31595312
Pubmed	Immortalization of human primary prostate epithelial cells via CRISPR inactivation of the CDKN2A locus and expression of telomerase.	CDKN2A TERT	4.20e-05	2	226	2	32873916
Pubmed	Detecting MYB and MYBL1 fusion genes in tracheobronchial adenoid cystic carcinoma by targeted RNA-sequencing.	MYB MYBL1	4.20e-05	2	226	2	31028361
Pubmed	Expression of DISC1 binding partners is reduced in schizophrenia and associated with DISC1 SNPs.	RELN DISC1	4.20e-05	2	226	2	16510495
Pubmed	Evidence that senescent human prostate epithelial cells enhance tumorigenicity: cell fusion as a potential mechanism and inhibition by p16INK4a and hTERT.	CDKN2A TERT	4.20e-05	2	226	2	18059027
Pubmed	MYB and MYBL1 in adenoid cystic carcinoma: diversity in the mode of genomic rearrangement and transcripts.	MYB MYBL1	4.20e-05	2	226	2	29410490
Pubmed	Low p16INK4a Expression in Early Passage Human Prostate Basal Epithelial Cells Enables Immortalization by Telomerase Expression Alone.	CDKN2A TERT	4.20e-05	2	226	2	27859428
Pubmed	Adenoid cystic carcinoma of the Bartholin's gland is underpinned by MYB- and MYBL1- rearrangements.	MYB MYBL1	4.20e-05	2	226	2	38368814
Pubmed	p16(INK4a) inactivation is not required to immortalize human mammary epithelial cells.	CDKN2A TERT	4.20e-05	2	226	2	12420227
Pubmed	Influence of genetic variations in platelet glycoproteins and eNOS in the development of arterial ischaemia of lower limbs in type 2 diabetes mellitus patients.	NOS3 GP1BA	4.20e-05	2	226	2	27888791
Pubmed	Arrest of spermatogenesis and defective breast development in mice lacking A-myb.	MYB MYBL1	4.20e-05	2	226	2	9109487
Pubmed	Relationship between the expression of hTERT and EYA4 mRNA in peripheral blood mononuclear cells with the progressive stages of carcinogenesis of the esophagus.	EYA4 TERT	4.20e-05	2	226	2	19939248
Pubmed	Proteomic-based detection of a protein cluster dysregulated during cardiovascular development identifies biomarkers of congenital heart defects.	ADAM15 JARID2 CHST3	5.70e-05	12	226	3	19156209
Pubmed	A mitochondrial protein compendium elucidates complex I disease biology.	SMDT1 KIF1B GLYCTK HMGCS2 COMTD1 CLPB COQ9 LIPT2 AURKAIP1 MTO1 PTCD3 NUDT19 GPD2 PDPR HDDC2 MSRB2 LRPPRC DDX28 ABHD11	6.08e-05	1047	226	19	18614015
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	KIF1B C2CD2L STARD9 RAB3GAP2 MTCL1 EP400 OBSL1 MED13L SUGP2 DISP2 SCRIB	8.04e-05	407	226	11	12693553
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	C2CD2L URB1 FBXL7 RAB3GAP2 GCN1 OBSL1 MED13L SCRIB	1.21e-04	225	226	8	12168954
Pubmed	The CARMA3-Bcl10-MALT1 Signalosome Drives NFκB Activation and Promotes Aggressiveness in Angiotensin II Receptor-Positive Breast Cancer.	CARD10 MALT1	1.26e-04	3	226	2	29259013
Pubmed	IRF7 regulates TLR2-mediated activation of splenic CD11c(hi) dendritic cells.	IRF7 ITGAX	1.26e-04	3	226	2	22815909
Pubmed	The p16(INK4A)/pRb pathway and telomerase activity define a subgroup of Ph+ adult Acute Lymphoblastic Leukemia associated with inferior outcome.	CDKN2A TERT	1.26e-04	3	226	2	25675863
Pubmed	Telomerase reverse transcriptase delays aging in cancer-resistant mice.	CDKN2A TERT	1.26e-04	3	226	2	19013273
Pubmed	A rare cause of syndromic short stature: 3M syndrome in three families.	CCDC8 OBSL1	1.26e-04	3	226	2	33258289
Pubmed	Determination of insulin resistance and its relationship with hyperandrogenemia,anti-Müllerian hormone, inhibin A, inhibin B, and insulin-like peptide-3 levels in adolescent girls with polycystic ovary syndrome.	INSL3 AMH	1.26e-04	3	226	2	31286756
Pubmed	GLTSCR2 promotes the nucleoplasmic translocation and subsequent degradation of nucleolar ARF.	CDKN2A NOP53	1.26e-04	3	226	2	27323397
Pubmed	Identification of physiologically relevant substrates for cloned Gal: 3-O-sulfotransferases (Gal3STs): distinct high affinity of Gal3ST-2 and LS180 sulfotransferase for the globo H backbone, Gal3ST-3 for N-glycan multiterminal Galbeta1, 4GlcNAcbeta units and 6-sulfoGalbeta1, 4GlcNAcbeta, and Gal3ST-4 for the mucin core-2 trisaccharide.	GAL3ST2 GAL3ST4	1.26e-04	3	226	2	14701868
Pubmed	The myb gene family in cell growth, differentiation and apoptosis.	MYB MYBL1	1.26e-04	3	226	2	10378697
Pubmed	Three M Syndrome	CCDC8 OBSL1	1.26e-04	3	226	2	20301654
Pubmed	Expression of hTERT immortalises normal human urothelial cells without inactivation of the p16/Rb pathway.	CDKN2A TERT	1.26e-04	3	226	2	16619045
Pubmed	Evaluation of imputation-based association in and around the integrin-alpha-M (ITGAM) gene and replication of robust association between a non-synonymous functional variant within ITGAM and systemic lupus erythematosus (SLE).	ITGAX TRIM72	1.26e-04	3	226	2	19129174
Pubmed	MYBL1 rearrangements and MYB amplification in breast adenoid cystic carcinomas lacking the MYB-NFIB fusion gene.	MYB MYBL1	1.26e-04	3	226	2	29149504
Pubmed	Inactivation of p16INK4a, with retention of pRB and p53/p21cip1 function, in human MRC5 fibroblasts that overcome a telomere-independent crisis during immortalization.	CDKN2A TERT	1.26e-04	3	226	2	15308640
Pubmed	The CARMA3-BCL10-MALT1 (CBM) complex contributes to DNA damage-induced NF-κB activation and cell survival.	CARD10 MALT1	1.26e-04	3	226	2	28717989
Pubmed	Alterations of INK4a(p16-p14ARF)/INK4b(p15) expression and telomerase activation in meningioma progression.	CDKN2A TERT	1.26e-04	3	226	2	11859969
Pubmed	The Potential Role of BRCA1-Associated ATM Activator-1 (BRAT1) in Regulation of mTOR.	RPTOR BRAT1	1.26e-04	3	226	2	25657994
Pubmed	Molecular cloning and characterization of a novel human galactose 3-O-sulfotransferase that transfers sulfate to gal beta 1-->3galNAc residue in O-glycans.	GAL3ST2 GAL3ST4	1.26e-04	3	226	2	11333265
Pubmed	Alterations in the p16(INK4a) and p53 tumor suppressor genes of hTERT-immortalized human fibroblasts.	CDKN2A TERT	1.26e-04	3	226	2	14743210
Pubmed	Tubby and tubby-like protein 1 are new MerTK ligands for phagocytosis.	TULP1 MERTK	1.26e-04	3	226	2	20978472
Pubmed	Gene-environment interaction in chronic kidney disease among people with type 2 diabetes from The Malaysian Cohort project: a case-control study.	KCNQ1 NOS3	1.26e-04	3	226	2	32012348
Pubmed	Estrogen receptor-alpha and endothelial nitric oxide synthase nuclear complex regulates transcription of human telomerase.	NOS3 TERT	1.26e-04	3	226	2	18519947
Pubmed	The genetics of 3-M syndrome: unravelling a potential new regulatory growth pathway.	CCDC8 OBSL1	1.26e-04	3	226	2	22156540
Pubmed	The CARMA3-Bcl10-MALT1 signalosome promotes angiotensin II-dependent vascular inflammation and atherogenesis.	CARD10 MALT1	1.26e-04	3	226	2	20605784
Pubmed	CARMA3/Bcl10/MALT1-dependent NF-kappaB activation mediates angiotensin II-responsive inflammatory signaling in nonimmune cells.	CARD10 MALT1	1.26e-04	3	226	2	17101977
Pubmed	Exome sequencing identifies CCDC8 mutations in 3-M syndrome, suggesting that CCDC8 contributes in a pathway with CUL7 and OBSL1 to control human growth.	CCDC8 OBSL1	1.26e-04	3	226	2	21737058
Pubmed	Efficient immortalization of primary human cells by p16INK4a-specific short hairpin RNA or Bmi-1, combined with introduction of hTERT.	CDKN2A TERT	1.26e-04	3	226	2	17233832
Pubmed	Mutations in CUL7, OBSL1 and CCDC8 in 3-M syndrome lead to disordered growth factor signalling.	CCDC8 OBSL1	1.26e-04	3	226	2	23018678
Pubmed	Nucleolin, a novel partner for the Myb transcription factor family that regulates their activity.	MYB MYBL1	1.26e-04	3	226	2	10660576
Pubmed	Inactivation of heat shock factor Hsf4 induces cellular senescence and suppresses tumorigenesis in vivo.	CDKN2A HSF4	1.26e-04	3	226	2	22355043
Pubmed	Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism.	ZSWIM8 PFAS COMTD1 MALT1 CLPB CASKIN2 WDR90 GP1BA FLII ZNF48 CPD TERT ABCB9 ARMC5 EIF4G1 MYB TEDC1	1.29e-04	925	226	17	28986522
Pubmed	Differential expression of PRAMEL1, a cancer/testis antigen, during spermatogenesis in the mouse.	PRAMEF11 PRAMEF15 PRAMEF4	1.72e-04	17	226	3	23565261
Pubmed	Mouse Pramel1 regulates spermatogonial development by inhibiting retinoic acid signaling during spermatogenesis.	PRAMEF11 PRAMEF15 PRAMEF4	1.72e-04	17	226	3	37781892
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	CDKN2A CCDC8 RASSF2 KIF1B MAST2 MDN1 CASKIN2 STARD9 RPTOR RAB3GAP2 MTCL1 HDAC7 LRPPRC EIF4G1 AKAP13 SCRIB	1.79e-04	861	226	16	36931259
Pubmed	Novel protein interactions with endoglin and activin receptor-like kinase 1: potential role in vascular networks.	DCAF6 KIF1B IRAK2 IRF7 NOS3 TRIM13	1.81e-04	126	226	6	24319055
Pubmed	The promoter of the oocyte-specific gene, Oog1, functions in both male and female meiotic germ cells in transgenic mice.	PRAMEF11 PRAMEF15 PRAMEF4	2.06e-04	18	226	3	23894331
Pubmed	Pramel15 facilitates zygotic nuclear DNMT1 degradation and DNA demethylation.	PRAMEF11 PRAMEF15 PRAMEF4	2.06e-04	18	226	3	39181896
Pubmed	Oogenesin is a novel mouse protein expressed in oocytes and early cleavage-stage embryos.	PRAMEF11 PRAMEF15 PRAMEF4	2.06e-04	18	226	3	12890732
Pubmed	Oocyte-specific gene Oog1 suppresses the expression of spermatogenesis-specific genes in oocytes.	PRAMEF11 PRAMEF15 PRAMEF4	2.06e-04	18	226	3	29731491
Pubmed	Identification of a new expanding family of genes characterized by atypical LRR domains. Localization of a cluster preferentially expressed in oocyte.	PRAMEF11 PRAMEF15 PRAMEF4	2.06e-04	18	226	3	14675769
Pubmed	A physical map of the genomic region on mouse chromosome 3 containing the hindshaker (hsh) mutation.	ADAM15 PKLR BCAN	2.43e-04	19	226	3	14706451
Pubmed	Pramel7 mediates ground-state pluripotency through proteasomal-epigenetic combined pathways.	PRAMEF11 PRAMEF15 PRAMEF4	2.43e-04	19	226	3	28604677
Pubmed	Research progress in pathogenic genes of hereditary non-syndromic mid-frequency deafness.	EYA4 TECTA	2.50e-04	4	226	2	27142990
Pubmed	Desialylation accelerates platelet clearance after refrigeration and initiates GPIbα metalloproteinase-mediated cleavage in mice.	CDKN2A GP1BA	2.50e-04	4	226	2	22101895
Pubmed	Thrombin-dependent NF-{kappa}B activation and monocyte/endothelial adhesion are mediated by the CARMA3·Bcl10·MALT1 signalosome.	CARD10 MALT1	2.50e-04	4	226	2	21041303
Pubmed	CXCL12/SDF-1 alpha activates NF-kappaB and promotes oral cancer invasion through the Carma3/Bcl10/Malt1 complex.	CARD10 MALT1	2.50e-04	4	226	2	20695076
Pubmed	A two-stage, p16(INK4A)- and p53-dependent keratinocyte senescence mechanism that limits replicative potential independent of telomere status.	CDKN2A TERT	2.50e-04	4	226	2	12077343
Pubmed	FBXL19 recruits CDK-Mediator to CpG islands of developmental genes priming them for activation during lineage commitment.	FBXL19 MED13L	2.50e-04	4	226	2	29809150
Pubmed	The 3M complex maintains microtubule and genome integrity.	CCDC8 OBSL1	2.50e-04	4	226	2	24793695
Pubmed	Reelin controls position of autonomic neurons in the spinal cord.	RELN NOS3	2.50e-04	4	226	2	10880573
Pubmed	Temporal patterns of A-myb and B-myb gene expression during testis development.	MYB MYBL1	2.50e-04	4	226	2	8808690
Pubmed	Loss of Reelin protects mice against arterial thrombosis by impairing integrin activation and thrombus formation under high shear conditions.	RELN GP1BA	2.50e-04	4	226	2	28943410
Pubmed	BRAF V600E, TERT promoter mutations and CDKN2A/B homozygous deletions are frequent in epithelioid glioblastomas: a histological and molecular analysis focusing on intratumoral heterogeneity.	CDKN2A TERT	2.50e-04	4	226	2	29105198
Pubmed	Bimp1, a MAGUK family member linking protein kinase C activation to Bcl10-mediated NF-kappaB induction.	CARD10 MALT1	2.50e-04	4	226	2	11387339
Pubmed	Detailed characterizations of cranial nerve anatomy in E14.5 mouse embryos/fetuses and their use as reference for diagnosing subtle, but potentially lethal malformations in mutants.	CC2D2A COL4A2	2.50e-04	4	226	2	36438572
Pubmed	Preferentially Expressed Antigen in Melanoma (PRAME) and the PRAME Family of Leucine-Rich Repeat Proteins.	PRAMEF11 PRAMEF15 PRAMEF4	2.84e-04	20	226	3	26694250
Pubmed	Oog1, an oocyte-specific protein, interacts with Ras and Ras-signaling proteins during early embryogenesis.	PRAMEF11 PRAMEF15 PRAMEF4	2.84e-04	20	226	3	16580637
Pubmed	Pramel7 mediates LIF/STAT3-dependent self-renewal in embryonic stem cells.	PRAMEF11 PRAMEF15 PRAMEF4	2.84e-04	20	226	3	21425410
Pubmed	Proteomic analysis and identification of cellular interactors of the giant ubiquitin ligase HERC2.	FLII CCDC22 OBSL1 TRMT2A EIF4G1 PRKAR2B	3.08e-04	139	226	6	25476789
Pubmed	Identification and developmental analysis of genes expressed by dopaminergic neurons of the substantia nigra pars compacta.	JARID2 CERS4 PATL1 RUFY3 DLL3	3.11e-04	90	226	5	15033168
Pubmed	The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.	EPPK1 IRAK2 AURKAIP1 MTCL1 NEURL1B PLD4 EIF4G1 SCRIB AP4M1	3.49e-04	332	226	9	37433992
Pubmed	Identification of phagocytosis regulators using magnetic genome-wide CRISPR screens.	RASSF2 APOBR ITGAX RPTOR EIF4G1 AKAP13	3.59e-04	143	226	6	30397336
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	MGAT4B EYA4 PFAS MAST2 FREM2 CASKIN2 OBSL1 PATL1 TRMT2A ARMC5 AKAP13 SCRIB SORL1	3.64e-04	650	226	13	38777146
Pubmed	RSPO-LGR4 functions via IQGAP1 to potentiate Wnt signaling.	URB1 PKHD1 GCN1 CPD LRPPRC EIF4G1 SCRIB	3.75e-04	202	226	7	24639526
Pubmed	Sertoli cell-only phenotype and scRNA-seq define PRAMEF12 as a factor essential for spermatogenesis in mice.	PRAMEF11 PRAMEF15 PRAMEF4	3.81e-04	22	226	3	31729367
Interaction	TOP3B interactions	TRPM4 MGAT4B EPPK1 ANKRD9 KIF1B PFAS CARD10 COMTD1 MAST2 KIAA2013 C2CD2L PCNX2 URB1 MDN1 RPTOR WDR90 BRAT1 GCN1 NUDT19 LRRC8E FLII ZNF48 EP400 TMEM158 PLEKHA4 PATL1 FBXL19 MED13L ZBED3 HDAC7 EML3 KIFC2 ANO8 MROH6 SUGP2 ZNF408 EIF4G1 DISP2 AKAP13 ARRDC2 DDX28	2.27e-08	1470	220	41	int:TOP3B
Cytoband	8q24.3	IQANK1 EPPK1 KIFC2 MROH6 WDR97 TMEM249 SCRIB	1.58e-06	113	226	7	8q24.3
Cytoband	1p36.21	PRAMEF9 PRAMEF11 PRAMEF15 PRAMEF4	2.71e-04	63	226	4	1p36.21
GeneFamily	PRAME family	PRAMEF9 PRAMEF11 PRAMEF15 PRAMEF4	2.50e-05	24	131	4	686
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	LRFN3 HMCN2 ALPK3 MERTK MXRA5 OBSL1 LRIT1	1.73e-04	161	131	7	593
GeneFamily	Immunoglobulin like domain containing	MALT1 HMCN2 ALPK3 MERTK ISLR2 MXRA5 OBSL1	5.19e-04	193	131	7	594
GeneFamily	WD repeat domain containing	DCAF6 DCAF8 WDR81 RPTOR WDR90 EML3 WDR97 WDR86	6.52e-04	262	131	8	362
ToppCell	medial-2-Hematologic-OLR1+_Classical_Monocyte\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	RASSF2 IRAK2 ITGAX JARID2 MERTK IL4I1 TMEM158 TYMP CSF3R RTL1	7.46e-08	198	226	10	d0a63cb48deecfdb8902c9229e457b7678aff178
ToppCell	medial-Hematologic-OLR1+_Classical_Monocyte-2\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	RASSF2 IRAK2 ITGAX JARID2 MERTK IL4I1 TMEM158 TYMP CSF3R RTL1	7.46e-08	198	226	10	74f79fd3b173c236e79b8b8f59a3b7c02ea082c6
ToppCell	medial-Hematologic-OLR1+_Classical_Monocyte\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	RASSF2 IRAK2 ITGAX JARID2 MERTK IL4I1 TMEM158 TYMP CSF3R RTL1	7.46e-08	198	226	10	3f21354eb3e5f0949aec21dc2a8940e70464ecc7
ToppCell	facs-Marrow-B-cells-18m-Hematologic-MPP_Fraction_B_+_C\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DISC1 INSL3 ST7L ITGAX ALPK3 GPR25 IRGQ CNNM3 ARMC5	3.68e-07	180	226	9	7368ab31c3273374ef260f0d710d4eea83cbc4a2
ToppCell	LPS-antiTNF-Epithelial_alveolar-Mes-like\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	COMTD1 APOBR MDN1 EME2 NAPSA RXFP4 DDX28 JPH3	4.33e-07	134	226	8	64979e1a056b7406e1be39c5ebe2f8d731ac3c17
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-6_LAMP5_CA13_(Lamp5_Lhx6_1)\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	EYA4 C8orf34 FREM2 FBXL7 COL4A2 SLCO5A1 LRIT1 MYB SLC22A31	4.43e-07	184	226	9	ae0a77e3e520a246b17776bb19503519636b02ee
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	C8orf34 FREM2 TFCP2L1 PKHD1 GPC5 NAPSA CSF3R AKAP13 SLC22A31	5.08e-07	187	226	9	5df9e1f5ca32217af255e76e6fb5afa346337811
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Hematopoietic-Myeloid-cDC2\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RASSF2 SIGLEC9 APOBR ITGAX HSF4 IL4I1 PLD4 TYMP CSF3R	5.31e-07	188	226	9	239bec13476dd43bebc2c6eba8d1fe35f2744673
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW09-Macroglial-Astrocyte\|GW09 / Sample Type, Dataset, Time_group, and Cell type.	IRAK2 COQ9 NOS3 COL4A2 CD248 HYAL1 PLEKHA4 EEPD1	6.74e-07	142	226	8	85e573616e54d41391b4ad8c3d38e4ca92112673
ToppCell	BAL-Control-Myeloid-cDC-cDC-cDC_4\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	RASSF2 KLHL33 CERS4 PLD4 TECTA KIAA1614 CNTNAP2 MYBL1	7.11e-07	143	226	8	5a279da1cd8e63db32f7c85a73b493c2121d0a96
ToppCell	BAL-Control-Myeloid-cDC-cDC-cDC_4\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	RASSF2 KLHL33 CERS4 PLD4 TECTA KIAA1614 CNTNAP2 MYBL1	7.90e-07	145	226	8	997bd540c43725a85ca97e4b79ebe0d336860287
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D122\|Adult / Lineage, Cell type, age group and donor	HMGCS2 C8orf34 TFCP2L1 NAPSA OBSL1 CSF3R AKAP13 SLC22A31	1.44e-06	157	226	8	31d1bd9138c60e8485664ec4144f987226e3eef9
ToppCell	390C-Epithelial_cells-Epithelial-H_(AT1)-\|390C / Donor, Lineage, Cell class and subclass (all cells)	EYA4 EPPK1 ERVW-1 MXRA5 RIPK4 CHADL PLCH2 CNTNAP2	1.66e-06	160	226	8	18ae6822915d16699beb9047baeef9b006901a35
ToppCell	390C-Epithelial_cells-Epithelial-H_(AT1)\|390C / Donor, Lineage, Cell class and subclass (all cells)	EYA4 EPPK1 ERVW-1 MXRA5 RIPK4 CHADL PLCH2 CNTNAP2	1.66e-06	160	226	8	830f17bad94de05612fe6d53d39e42a4b3f3e2f3
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)\|Adult / Lineage, Cell type, age group and donor	HMGCS2 C8orf34 TFCP2L1 GPC5 NAPSA CSF3R AKAP13 SLC22A31	1.91e-06	163	226	8	e819a1d6d28290854aa0672b3a18fa9e293d8f23
ToppCell	NS-critical-d_0-4-Epithelial-unknown_epithelial\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	EYA4 EPPK1 LRFN3 FBXL7 ALPK3 NUDT19 LRRC8E PLEKHA4	2.18e-06	166	226	8	dd02bbe4af609c6348dc92417254f4740f2900a8
ToppCell	390C-Epithelial_cells-Epithelial-H_(AT1)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	EYA4 ERVW-1 CHST3 MXRA5 TMEM158 CHADL PLCH2 CNTNAP2	2.85e-06	172	226	8	aff37b9689b0d30ee7097d997d9588efc475c8fd
ToppCell	390C-Epithelial_cells-Epithelial-H_(AT1)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	EYA4 ERVW-1 CHST3 MXRA5 TMEM158 CHADL PLCH2 CNTNAP2	2.85e-06	172	226	8	bb542f6ca4eb8167129bc84ca1160a54fbb68731
ToppCell	Hippocampus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Calb2\|Hippocampus / BrainAtlas - Mouse McCarroll V32	GASK1B KEL WNT9B TERT PKHD1L1 KASH5	3.08e-06	79	226	6	03c5af851b53800eced1c74e9da374c71092bcd4
ToppCell	droplet-Lung-LUNG-1m-Myeloid-Ccr7+_Dendritic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CDKN2A RASSF2 DISC1 GAL3ST2 EME2 IL4I1 SLCO5A1 WDR86	3.10e-06	174	226	8	7be0c6248e77f2d0260b852b01e17892f7828f1b
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Hematopoietic-Myeloid-cDC2\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RASSF2 APOBR ITGAX PLD4 FBXL19 TYMP CSF3R MROH6	3.82e-06	179	226	8	ce95b601bf17ae8167d382a105384b9e65e9407f
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Myeloid-Dendritic\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	IRF7 APOBR KCNQ1 IL4I1 PLD4 NAPSA TYMP PRKAR2B	4.88e-06	185	226	8	0a87d2ee8fffc812224c05a26c729733a5e64d2c
ToppCell	wk_15-18-Epithelial-Distal_epithelial_progenitor-epi-tip_intermediate\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	FREM2 TFCP2L1 PKHD1 PDPR RIPK4 FBXL19 MAMDC4 WDR97	4.88e-06	185	226	8	636505a3d96f75d951ab42bcf8af6ae07abc732d
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Myeloid-Dendritic-conventional_dendritic_cell\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	IRF7 APOBR KCNQ1 IL4I1 PLD4 NAPSA TYMP PRKAR2B	4.88e-06	185	226	8	e63fde030be822ebf32143a41f8cc684cb720f5b
ToppCell	3'-Adult-LargeIntestine-Hematopoietic-Myeloid-Lymphoid_DC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RELN EYA4 RASSF2 ITGAX MERTK IL4I1 BCAN SLCO5A1	5.28e-06	187	226	8	d69f4eee0304a7db226275ab77fc9d5d2b6f3a07
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ADAM15 FBXL7 CASKIN2 GPC5 NEURL1B ISLR2 HYAL1 PRKCH	6.65e-06	193	226	8	1f978e102a029a6beb10913052cd0a20c7253e8e
ToppCell	Adult-Immune-interstitial_macrophage_(C1Q_positive)-D231\|Adult / Lineage, Cell type, age group and donor	RASSF2 DISC1 ITGAX JARID2 MALT1 MERTK TYMP EEPD1	6.91e-06	194	226	8	800d3d7a9e864d2d6a100a4e4af22f45d5790a8d
ToppCell	distal-Hematologic-OLR1+_Classical_Monocyte\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	IRAK2 ITGAX JARID2 IL4I1 TMEM158 TYMP ETV3L CSF3R	7.45e-06	196	226	8	3f57216dbc9ef28fca09bbb8805f7c15b03b99e8
ToppCell	distal-Hematologic-OLR1+_Classical_Monocyte-2\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	IRAK2 ITGAX JARID2 IL4I1 TMEM158 TYMP ETV3L CSF3R	7.45e-06	196	226	8	80fc5b9e04ead0b38304dccbe39f66575e2bf203
ToppCell	Bronchial-NucSeq-Immune_Myeloid-Macrophage_other-Macrophage_intermediate\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	RASSF2 DISC1 IRAK2 ITGAX JARID2 MERTK BEST1 PRKAR2B	7.73e-06	197	226	8	e2983ae16c72371fbf0e5c123de9f4d900724e5e
ToppCell	Tracheal-10x3prime_v2-Immune_Myeloid-Dendritic_cell-DC_2\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	RASSF2 INSL3 APOBR ITGAX JARID2 PLD4 RPGRIP1 CSF3R	7.73e-06	197	226	8	febafd8f0f5bb9a09f496f240e6b6b5e9275669b
ToppCell	BAL-Control-Myeloid-cDC-cDC-cDC_0\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	RASSF2 GASK1B MALT1 MERTK IL4I1 PLD4 GAL3ST4 SORL1	8.02e-06	198	226	8	59214e34b077dffa989c48635fdef143f57f1320
ToppCell	BAL-Control-Myeloid-cDC-cDC-cDC_0\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	RASSF2 GASK1B MALT1 MERTK IL4I1 PLD4 GAL3ST4 SORL1	8.02e-06	198	226	8	7f7024b26337ae2bc7f57c3274a7dfdaaa64ab7c
ToppCell	distal-2-Hematologic-OLR1+_Classical_Monocyte\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	IRAK2 ITGAX JARID2 IL4I1 TMEM158 TYMP ETV3L CSF3R	8.02e-06	198	226	8	43179d92e45b14f6f3d63949a9d88c2c7531f7d1
ToppCell	Tracheal-NucSeq-Immune_Myeloid-Dendritic_cell-DC_activated\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	APOBR C2CD2L IL4I1 PLD4 NAPSA BEST1 EVA1B CSF3R	8.32e-06	199	226	8	6dc446a5d183b01bdf227e45bd88d0b3d8b1c56a
ToppCell	IPF-Myeloid-Macrophage\|Myeloid / Disease state, Lineage and Cell class	SLC39A11 IRAK2 ITGAX GASK1B JARID2 MERTK COL4A2 EEPD1	8.32e-06	199	226	8	3c2b362d5e824e1a04830e70352f8818de984174
ToppCell	Tracheal-10x3prime_v2-Stromal-Peri/Epineurial_\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	FBXL7 MTARC1 GPD2 MTHFSD PLEKHA4 KIAA1614 ARMC5 PSPN	8.63e-06	200	226	8	f7c3a8f5ac156c05ad7335d6d142c154c7d86449
ToppCell	droplet-Liver-Hepatocytes-24m-Myeloid-macrophage/monocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CDKN2A ITGAX JARID2 CC2D2A IL4I1 NAPSA EP400	1.58e-05	157	226	7	d8e283414a770f05d71f0455d0822e9a9660b115
ToppCell	droplet-Liver-Hepatocytes-24m-Myeloid-myeloid_leukocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CDKN2A ITGAX JARID2 CC2D2A IL4I1 NAPSA EP400	1.58e-05	157	226	7	165e98bf944572cafbc06ef43c9eab7bd6bea1c2
ToppCell	droplet-Heart-nan-24m-Mesenchymal-nan\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZSWIM8 HSF4 CD248 RUFY3 WDR86 ABHD11 SORL1	1.72e-05	159	226	7	7ad3a91d29639b32f6264c91f401c14a35469ac0
ToppCell	PND07-Immune-Immune_Myeloid-DC-maDC\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CDKN2A RASSF2 STARD7 GAL3ST2 WDR90 IL4I1 SLCO5A1	1.79e-05	160	226	7	7db30647b596f0c419087e6fabb9b99dcd5bddd4
ToppCell	PND07-Immune-Immune_Myeloid-DC-maDC-maDC_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CDKN2A RASSF2 STARD7 GAL3ST2 WDR90 IL4I1 SLCO5A1	1.79e-05	160	226	7	01f22cdb2a2f73776b7f91746e95c1850df94235
ToppCell	CD8+_Memory_T_cell-FLU-1\|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster	SLC39A11 GAL3ST2 C2CD2L CASKIN2 NAPSA ZNF654 PSPN	1.94e-05	162	226	7	76f39935763848ea6e7917b2f9f1432c543063d9
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_vein-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ADAM15 FBXL7 NOS3 HYAL1 WNT9B DISP2 PRKCH	2.27e-05	166	226	7	f7926ee266dcbf10df375cd921f1db5a2fa604f8
ToppCell	PND28-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SLC39A11 QSOX1 FBXL7 NOS3 GP1BA TMEM158 EEPD1	2.36e-05	167	226	7	f01b96173deda0239fa482989873cf308e49d48c
ToppCell	PND28-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SLC39A11 QSOX1 FBXL7 NOS3 GP1BA TMEM158 EEPD1	2.36e-05	167	226	7	5fc85a05124cd2324e1b8ff940193880f83cd8af
ToppCell	mild_COVID-19_(asymptomatic)-pDC\|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)	CC2D2A MTCL1 PLD4 ZBED3 ABCB9 WDR86 MYB	2.45e-05	168	226	7	968405ea56f7d001ef83ff9274610923c3b2d55d
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Hematologic-fibroblast\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CDKN2A HMGCS2 WDR90 MERTK PLD4 NAPSA BEST1	2.54e-05	169	226	7	15a9183c838cc6384d7f5dfeae3d30602964c9b3
ToppCell	3'_v3-lymph-node_spleen-Hematopoietic_progenitors-Progenitor_Erythro-Mega\|lymph-node_spleen / Manually curated celltypes from each tissue	ATP7B KEL OBSL1 SLC1A6 PRKAR2B HACD1 MYB	2.74e-05	171	226	7	3ecd0a074344179c57eb2d9a857ba594904d00fa
ToppCell	Monocytes-IFN-activated_Monocytes\|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	SIGLEC9 SLC15A3 ITGAX IL4I1 BEST1 TYMP CSF3R	2.74e-05	171	226	7	df1b631618839bee4a18a2ba9c730321e5015f36
ToppCell	5'-Adult-LargeIntestine-Epithelial-neuro-epithelial-EECs\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CD164L2 KIF1B ALPK3 KLHL33 SLCO5A1 DLL3 RXFP4	2.74e-05	171	226	7	dd37e1693a5cfc42e40992d504f92048a8038b52
ToppCell	3'_v3-lymph-node_spleen-Myeloid_Dendritic-migDC\|lymph-node_spleen / Manually curated celltypes from each tissue	RELN EYA4 GPC5 IL4I1 PRAMEF11 ETV3L SLCO5A1	2.85e-05	172	226	7	1b24bed3cd8e3fa463c5e7cefdf9e99e639e2f84
ToppCell	3'-GW_trimst-2-LargeIntestine-Endothelial-lymphatic_endothelial-LEC1_(ACKR4+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RELN MALT1 EME2 RPGRIP1 REX1BD ZBED3 ARRDC2	3.06e-05	174	226	7	4a18b51501eaaeb7907e99316ba8ae15b2c7d529
ToppCell	5'-Adult-LargeIntestine-Hematopoietic-Myeloid-Lymphoid_DC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RELN EYA4 RASSF2 GPC5 MERTK BCAN SLCO5A1	3.06e-05	174	226	7	16204ff504b7b382b4d90ca35003ad5336020e07
ToppCell	droplet-Lung-1m-Hematologic-myeloid-myeloid_dendritic_cell-Ccr7+_dendritic\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CDKN2A RASSF2 DISC1 GAL3ST2 IL4I1 SLCO5A1 WDR86	3.18e-05	175	226	7	1b910c08d2bfbcc77431ee66103e63a11a9d39fe
ToppCell	LPS-antiTNF-Epithelial_alveolar-Mes-like-AT1_Progenitor\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	COMTD1 APOBR AURKAIP1 EME2 NAPSA EML3 ZNF408	3.42e-05	177	226	7	164ffbbf798defa3728197deb1a14b661490e525
ToppCell	10x5'-GI_large-bowel-Lymphocytic_T_CD4-Tnaive/CM_CD4\|GI_large-bowel / Manually curated celltypes from each tissue	EPPK1 PFAS BRAT1 GAL3ST4 CHADL DLL3 ARRDC2	3.42e-05	177	226	7	eb87ea93e36a8f97442ec8515f658ee61932dc0f
ToppCell	metastatic_Brain-Myeloid_cells-Activated_DCs\|metastatic_Brain / Location, Cell class and cell subclass	RASSF2 C2CD2L IL4I1 PLD4 FBXL19 TYMP SLCO5A1	3.42e-05	177	226	7	739496fcc4156f4d5e3de9cd21cf3856037f0678
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-6_LAMP5_CA13_(Lamp5_Lhx6_1)\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	EYA4 C8orf34 FREM2 FBXL7 COL4A2 SLCO5A1 MYB	3.54e-05	178	226	7	f332c7a96844abecf05ca057480fbea9296688a2
ToppCell	PND14-Immune-Immune_Myeloid-Megakaryocyte/Platelet\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SLC39A11 LY6G6F GP1BA TMEM158 CSF3R SUGP2 PRKAR2B	3.54e-05	178	226	7	cb91558469ae0748106fb0b6d702edb0ff21a884
ToppCell	PND14-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet-Megakaryocyte/Platelet_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SLC39A11 LY6G6F GP1BA TMEM158 CSF3R SUGP2 PRKAR2B	3.54e-05	178	226	7	63f5880a5b514e20ef2c07a6a9cb8df34e6cede5
ToppCell	PND14-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SLC39A11 LY6G6F GP1BA TMEM158 CSF3R SUGP2 PRKAR2B	3.54e-05	178	226	7	82c84f8b8a7e6a3d3be3351b348a37143279c100
ToppCell	10x5'-lymph-node_spleen-Myeloid_Mac-Intestinal_macrophages\|lymph-node_spleen / Manually curated celltypes from each tissue	ITGAX TFCP2L1 CROCC2 ALPK3 MERTK OBSL1 TYMP	3.80e-05	180	226	7	7be7d7a6906fff6dbdecd9cb013d855aba4eda2a
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Myeloid-Dendritic-conventional_dendritic_cell-DC_c2-CD1C\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	IRF7 APOBR IL4I1 PLD4 NAPSA TYMP PRKAR2B	3.94e-05	181	226	7	6771f2c72073c59aab905945a619907b7fd0fd77
ToppCell	5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage-Monocyte-derived_macrophage_L.1.2.3.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SIGLEC9 IRAK2 SLC15A3 ITGAX IL4I1 TMEM158 TYMP	4.37e-05	184	226	7	857ca1fc4de07b300839b22924211dc624453841
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic-Classical_Dendritic_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	RASSF2 DISC1 IRAK2 APOBR ITGAX TYMP SLCO5A1	4.37e-05	184	226	7	4f4aeef3b821a003e857fe4a195124d44b2d7479
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_low-phase\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CROCC2 ISLR2 SLC1A6 MYB MYBL1 TEDC1	4.48e-05	126	226	6	8ae631694bbba40f64e55e2be8162d7a40eeadc5
ToppCell	COVID-19_Moderate-HSPC\|COVID-19_Moderate / disease group, cell group and cell class	CCDC8 KEL NEURL1B OBSL1 SLC1A6 HACD1 MYB	4.53e-05	185	226	7	cacc6ab5f26f6c803894567fb838ea06eaa7efe5
ToppCell	saliva-Mild-Moderate_progression_d12-25-Myeloid-Monocytic-Classical_Monocyte-Mono_c2-CD14-HLA-DPB1\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	RASSF2 IRAK2 ITGAX PKHD1 BEST1 CPD CSF3R	4.53e-05	185	226	7	42690b95e2e7d56c822211bb1150acb787cfe2e8
ToppCell	PCW_07-8.5-Hematologic_ErythroMegGranulo-Hem_ErythroMeg\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	RELN ANKRD9 LY6G6F PKLR KEL PKHD1L1 EPB42	4.68e-05	186	226	7	3b60a153e6cfc1b977a1f8b8f3bcaf75d1f4ff5b
ToppCell	PCW_07-8.5-Hematologic_ErythroMegGranulo\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	RELN ANKRD9 LY6G6F PKLR KEL PKHD1L1 EPB42	4.68e-05	186	226	7	294839944266407c40ef86e1d3e0fce4652b70ff
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-6_LAMP5_CA13_(Lamp5_Lhx6_1)\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	EYA4 C8orf34 FREM2 FBXL7 COL4A2 SLCO5A1 MYB	4.68e-05	186	226	7	77592a6397b44b2b59a4fc39d7224dd95343efe6
ToppCell	10x3'2.3-week_17-19-Endothelial-stroma-proliferating_EC\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	ADAM15 CARD10 HMCN2 CASKIN2 NEURL1B COL4A2 MXRA5	4.68e-05	186	226	7	a844d4f79e0ad5d6c60a4488ffd8f4f21b7eed04
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Myeloid-Dendritic-conventional_dendritic_cell-DC_c2-CD1C\|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)	TRPM4 GPR108 SLC15A3 C8orf34 QSOX1 RUFY3 CYB561D1	4.68e-05	186	226	7	b9e0a819cd0b250f077b26eba99e6986d68d647b
ToppCell	PCW_10-12-Hematologic_ErythroMegGranulo-Hem_ErythroMeg\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	ANKRD9 LY6G6F KEL GP1BA TMEM158 PKHD1L1 EPB42	4.68e-05	186	226	7	1c39ced3b32dba2832991284720b6c5f508a2e73
ToppCell	3'_v3-bone_marrow-Hematopoietic_Erythro-Mega\|bone_marrow / Manually curated celltypes from each tissue	LY6G6F PKLR KEL GP1BA PRKAR2B EPB42 MYB	4.68e-05	186	226	7	9ff3c30b1728707bb8f9422941333fe3b2c430f4
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L5-6_LAMP5_SFTA3_(Lamp5_Lhx6_2)\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	EYA4 FREM2 FBXL7 COL4A2 SLCO5A1 EEPD1 MYB	5.01e-05	188	226	7	8268574584e5fb869a6cb8bbd7135cd7454a6a25
ToppCell	TCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Lobular_Carcinoma-6\|TCGA-Breast / Sample_Type by Project: Shred V9	WDR81 HMCN2 PLD4 ISLR2 WNT9B HDAC7 DACT3	5.01e-05	188	226	7	c90669b51e1902fe7726555290c91c92a911df83
ToppCell	10x5'v1-week_17-19-Hematopoietic\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	LY6G6F PKLR KEL GP1BA CHADL PKHD1L1 PRKAR2B	5.01e-05	188	226	7	c00ba0abd0c7bb2c8f9166a2ac6220aae4f4d857
ToppCell	5'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-venous_capillary\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ADAM15 GASK1B CASKIN2 NOS3 COL4A2 HDAC7 PRKCH	5.01e-05	188	226	7	0026c9479b30fb39daa91cfa220a88f9c9e65fe7
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-6_LAMP5_CA13_(Lamp5_Lhx6_1)\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	EYA4 FREM2 FBXL7 COL4A2 SLCO5A1 EEPD1 MYB	5.01e-05	188	226	7	3139540a656c0436b2123ea50741ff8d00112165
ToppCell	Adult\|World / Lineage, Cell type, age group and donor	SLC39A11 ITGAX C8orf34 NAPSA TYMP CSF3R SLC22A31	5.18e-05	189	226	7	5cd285bfad973125d46d704fec18b21266a63379
ToppCell	TCGA-Kidney-Primary_Tumor\|TCGA-Kidney / Sample_Type by Project: Shred V9	CDKN2A APOBR ITGAX HSF4 GAL3ST4 TYMP CAPN15	5.36e-05	190	226	7	773c4575d22483d89a54c8db0e09905deed0d088
ToppCell	TCGA-Kidney-Primary_Tumor-Renal_Cell_Carcinoma\|TCGA-Kidney / Sample_Type by Project: Shred V9	CDKN2A APOBR ITGAX HSF4 GAL3ST4 TYMP CAPN15	5.36e-05	190	226	7	e3696e7542424c03d0a41136b10729a3dd09549a
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-6_LAMP5_CA13_(Lamp5_Lhx6_1)\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	EYA4 C8orf34 FREM2 FBXL7 COL4A2 SLCO5A1 MYB	5.36e-05	190	226	7	2f54da2bee411f8868348a4c37034184b8f58a89
ToppCell	Fetal_29-31_weeks-Immune-monocyte-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	SIGLEC9 ITGAX JARID2 MALT1 IL4I1 TYMP CSF3R	5.36e-05	190	226	7	ad297172a74a80ed5c10f921e15efd1da0fd2d6b
ToppCell	PCW_13-14-Hematologic_Myeloid-Hem_Myeloid_dendritic\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	SIGLEC9 IRAK2 APOBR ITGAX IL4I1 PLD4 TYMP	5.54e-05	191	226	7	03e1ac489e918c7affc1cdc09fb3eb255bcf80e5
ToppCell	PCW_10-12-Hematologic_Myeloid-Hem_Myeloid_dendritic\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	SIGLEC9 IRAK2 APOBR ITGAX IL4I1 PLD4 TYMP	5.54e-05	191	226	7	a5ee4d72b2311c8fa98ff73adc2499debb2014f1
ToppCell	Control-Myeloid-transitional_Macro\|Control / Disease group,lineage and cell class （2021.01.30）	SLC39A11 GASK1B KEL MERTK IL4I1 GAL3ST4 EEPD1	5.54e-05	191	226	7	3ed0b1ff628a165e3c92c2e493206015f57dccfe
ToppCell	COVID-19-lung-AT2\|lung / Disease (COVID-19 only), tissue and cell type	C8orf34 FREM2 TFCP2L1 GPC5 NAPSA CSF3R SLC22A31	5.54e-05	191	226	7	276455a64c2c3503d5048615762eb2ee37f0ac70
ToppCell	proximal-Hematologic-Platelet/Megakaryocyte\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	DISC1 INSL3 CLPB WDR97 TMEM249 DLL3 CYB561D1	5.72e-05	192	226	7	522d1bb15edf1d6006b80289bd3baadb99584ae8
ToppCell	BAL-Control-Myeloid-cDC-cDC-cDC_10\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	RASSF2 MALT1 GPC5 IL4I1 CERS4 ETV3L SLCO5A1	5.72e-05	192	226	7	d5a7b546ebfb2e757dd9c64cb1b651f6ed0e0fc7
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	C8orf34 FREM2 TFCP2L1 PKHD1 GPC5 AKAP13 SLC22A31	5.72e-05	192	226	7	29f49f00770c991b5f27e4cb701dd2d2d6cb7178
ToppCell	PCW_10-12-Hematologic_Myeloid-Hem_Myeloid_monocytic-im_immature_monocyte2_(4)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	SIGLEC9 IRAK2 SLC15A3 APOBR ITGAX PLD4 CSF3R	5.72e-05	192	226	7	aa65557b35d3eba9f24b970849255d05174d1c05
ToppCell	BAL-Control-Myeloid-cDC-cDC-cDC_10\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	RASSF2 MALT1 GPC5 IL4I1 CERS4 ETV3L SLCO5A1	5.72e-05	192	226	7	2c69f3f388b69fb1c1968c923cdbab90658883dd
ToppCell	proximal-3-Hematologic-Platelet/Megakaryocyte\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	DISC1 INSL3 CLPB WDR97 TMEM249 DLL3 CYB561D1	5.72e-05	192	226	7	f5f83dec37dff32a0c471cb05d23d13b0b0ad0c9
ToppCell	proximal-Hematologic-Platelet/Megakaryocyte-3\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	DISC1 INSL3 CLPB WDR97 TMEM249 DLL3 CYB561D1	5.72e-05	192	226	7	57899a905ca3e336bb7f31edc6418a2546b9891a
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_1\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RELN EYA4 C8orf34 FBXL7 COL4A2 EEPD1 MYB	5.91e-05	193	226	7	294cb5b580bb83fe0eb04f112d5507aac35d4d44
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RELN EYA4 C8orf34 FBXL7 COL4A2 EEPD1 MYB	5.91e-05	193	226	7	3d3c45d5ff6f3396a1990615aae9fe176e799994
ToppCell	CTRL-Myeloid-Monocyte_Macrophage\|CTRL / Disease state, Lineage and Cell class	RASSF2 ITGAX GASK1B JARID2 MERTK IL4I1 PLD4	6.11e-05	194	226	7	927480f56cccd3940b689f3c40ee132fe3e63745
Drug	Albendazole [54965-21-8]; Down 200; 15uM; HL60; HG-U133A	DCAF8 PFAS URB1 MDN1 GCN1 HDDC2 IRGQ TERT SUGP2 EIF4G1 MYB	3.72e-06	194	224	11	1547_DN
Drug	Ivermectin [70288-86-7]; Down 200; 4.6uM; PC3; HT_HG-U133A	ATP7B DISC1 PCNX2 REX1BD TUT1 EVA1B SUGP2 CNTNAP2 AKAP13 MYB CAPN15	4.99e-06	200	224	11	5853_DN
Disease	granulosa cell tumor (is_marker_for)	CDKN2A AMH PRKAR2B	5.70e-05	11	211	3	DOID:2999 (is_marker_for)
Disease	3-M syndrome	CCDC8 OBSL1	1.52e-04	3	211	2	cv:C1848862
Disease	severe congenital neutropenia (is_implicated_in)	CLPB CSF3R	1.52e-04	3	211	2	DOID:0050590 (is_implicated_in)
Disease	3-M syndrome (is_implicated_in)	CCDC8 OBSL1	1.52e-04	3	211	2	DOID:0060241 (is_implicated_in)
Disease	autistic disorder (is_implicated_in)	RELN DISC1 JARID2 CNTNAP2	2.30e-04	42	211	4	DOID:12849 (is_implicated_in)
Disease	Tinnitus	ITGAX C8orf34 PKHD1 GPC5 SPATA31A1 CNTNAP2	3.56e-04	130	211	6	HP_0000360
Disease	Major Depressive Disorder	CDKN2A RELN ATP7B DISC1 IRF7 TERT SLC1A6 CNTNAP2	3.83e-04	243	211	8	C1269683
Disease	blood urea nitrogen measurement	ANKRD9 TFCP2L1 CLCNKB PKHD1 WDR90 COL4A2 WNT9B KIAA1614 PRKAR2B AKAP13 SORL1	4.43e-04	452	211	11	EFO_0004741
Disease	teratoma (is_marker_for)	TYMP TERT	5.02e-04	5	211	2	DOID:3307 (is_marker_for)
Disease	STROKE, ISCHEMIC	NOS3 PRKCH	5.02e-04	5	211	2	601367
Disease	Ischemic stroke	NOS3 PRKCH	5.02e-04	5	211	2	cv:C0948008
Disease	Leber Congenital Amaurosis	TULP1 MERTK RPGRIP1	5.02e-04	22	211	3	C0339527
Disease	Unipolar Depression	CDKN2A RELN ATP7B DISC1 IRF7 TERT SLC1A6 CNTNAP2	5.84e-04	259	211	8	C0041696
Disease	leiomyosarcoma (is_marker_for)	CDKN2A TERT	7.49e-04	6	211	2	DOID:1967 (is_marker_for)
Disease	Retinitis Pigmentosa	TULP1 MERTK RPGRIP1 BEST1 ZNF408	9.24e-04	104	211	5	C0035334
Disease	hepatitis C virus infection, cirrhosis of liver	TULP1 MERTK	1.04e-03	7	211	2	EFO_0001422, EFO_0003047
Disease	Familial melanoma	CDKN2A TERT	1.39e-03	8	211	2	cv:C1512419
Disease	Malignant melanoma of skin	CDKN2A TERT	1.39e-03	8	211	2	cv:C0151779
Disease	Melanoma	CDKN2A TERT	1.39e-03	8	211	2	cv:C0025202
Disease	platelet crit	CDKN2A MGAT4B ANKRD9 ST7L EPX APOBR ITGAX KCND1 KCNQ1 GP1BA COL4A2 TERT HDAC7 KIAA1614 MYB SORL1	1.44e-03	952	211	16	EFO_0007985
Disease	Malignant Glioma	CDKN2A TERT MYB MYBL1	1.61e-03	70	211	4	C0555198
Disease	mixed gliomas	CDKN2A TERT MYB MYBL1	1.61e-03	70	211	4	C0259783
Disease	familial melanoma (is_implicated_in)	CDKN2A TERT	1.77e-03	9	211	2	DOID:6846 (is_implicated_in)
Disease	melanoma	CDKN2A HMCN2 COL4A2 TERT SLC22A31	2.16e-03	126	211	5	EFO_0000756
Disease	neuroblastoma (is_implicated_in)	CDKN2A KIF1B	2.21e-03	10	211	2	DOID:769 (is_implicated_in)
Disease	Familial Atypical Mole Melanoma Syndrome	CDKN2A TERT	2.68e-03	11	211	2	C2314896
Disease	Posterior Choroidal Artery Infarction	NOS3 PRKCH	2.68e-03	11	211	2	C0887799
Disease	Cerebral Infarction, Left Hemisphere	NOS3 PRKCH	2.68e-03	11	211	2	C0751010
Disease	Anterior Choroidal Artery Infarction	NOS3 PRKCH	2.68e-03	11	211	2	C0751012
Disease	Cerebral Infarction, Right Hemisphere	NOS3 PRKCH	2.68e-03	11	211	2	C0751011
Disease	Subcortical Infarction	NOS3 PRKCH	2.68e-03	11	211	2	C0751014
Disease	Cerebral Infarction	NOS3 PRKCH	2.68e-03	11	211	2	C0007785
Disease	thyroid carcinoma	PCNX2 CHST3 TERT	2.73e-03	39	211	3	EFO_0002892
Disease	serum urea measurement	ADAM15 TFCP2L1 COL4A2 WNT9B PRKAR2B SORL1	2.88e-03	195	211	6	EFO_0009795
Disease	acute myeloid leukemia (is_implicated_in)	CDKN2A NOS3 TERT CSF3R	3.14e-03	84	211	4	DOID:9119 (is_implicated_in)
Disease	retinitis pigmentosa (is_implicated_in)	TULP1 CC2D2A RPGRIP1	3.15e-03	41	211	3	DOID:10584 (is_implicated_in)
Disease	Glioma	CDKN2A TERT MYB MYBL1	3.56e-03	87	211	4	C0017638
Disease	mood disorder	RELN SORL1	3.77e-03	13	211	2	EFO_0004247
Disease	Disorder of eye	TULP1 FREM2 CC2D2A MERTK RPGRIP1 BEST1	4.33e-03	212	211	6	C0015397
Disease	lysophosphatidylcholine 15:0 measurement	PKHD1 PATL1	4.38e-03	14	211	2	EFO_0020941
Disease	Neuroblastoma	CDKN2A KIF1B TERT	4.64e-03	47	211	3	C0027819
Disease	Meckel-Gruber syndrome	CC2D2A RPGRIP1	5.03e-03	15	211	2	C0265215
Disease	quinate measurement	KCNQ1 EEPD1	5.03e-03	15	211	2	EFO_0021167
Disease	fetal genotype effect measurement, body weights and measures	DISC1 TULP1 KCNQ1	5.21e-03	49	211	3	EFO_0004324, EFO_0007959
Disease	hepatocellular carcinoma (implicated_via_orthology)	CDKN2A ATP7B BECN2	5.21e-03	49	211	3	DOID:684 (implicated_via_orthology)
Disease	Leber congenital amaurosis	TULP1 RPGRIP1	5.72e-03	16	211	2	cv:C0339527
Disease	Spondyloepiphyseal Dysplasia	CHST3 DLL3	5.72e-03	16	211	2	C0038015
Disease	atherosclerosis (is_implicated_in)	NOS3 COL4A2	5.72e-03	16	211	2	DOID:1936 (is_implicated_in)
Disease	triacylglycerol 50:5 measurement	LRTM2 LRRC8E	5.72e-03	16	211	2	EFO_0010412
Disease	Spondyloepiphyseal Dysplasia Tarda, X-Linked	CHST3 DLL3	5.72e-03	16	211	2	C3541456
Disease	anthranilic acid measurement	KIF1B KCNQ1	5.72e-03	16	211	2	EFO_0010460
Disease	Schwartz-Jampel Syndrome, Type 1	CHST3 DLL3	5.72e-03	16	211	2	C4551479
Disease	Schwartz-Jampel Syndrome	CHST3 DLL3	5.72e-03	16	211	2	C0036391
Disease	Melnick-Needles Syndrome	CHST3 DLL3	5.72e-03	16	211	2	C0025237
Disease	Squamous cell carcinoma of the head and neck	CDKN2A ATP7B MERTK	6.16e-03	52	211	3	C1168401
Disease	major depressive disorder (is_implicated_in)	DISC1 CNTNAP2	6.45e-03	17	211	2	DOID:1470 (is_implicated_in)
Disease	Van Buchem disease	CHST3 DLL3	6.45e-03	17	211	2	C0432272
Disease	Mouth Neoplasms	CDKN2A ATP7B HMGCS2	6.84e-03	54	211	3	C0026640
Disease	Malignant neoplasm of mouth	CDKN2A ATP7B HMGCS2	6.84e-03	54	211	3	C0153381

Protein segments in the cluster

Peptide	Gene	Start	Entry
WQGLEELRLRRLQGT	PPP2R5B	461	Q15173
PVLLRRRRGELGTAW	MAMDC4	371	Q6UXC1
SLEGWTGQDRLLIPR	LINC00479	26	Q96M42
AELRKAGLWSQRRLP	EP400	786	Q96L91
LLNKRRGSVPILRQW	EPB42	241	P16452
RGSVPILRQWLTGRG	EPB42	246	P16452
VPTVRSGWIQGLRSL	BRAT1	116	Q6PJG6
GLLGRPGWRDSELLR	CARD10	956	Q9BWT7
PRLTRWLRRGSGILA	CYB561D1	16	Q8N8Q1
GLPLSRWLGVRDQTR	CERS4	61	Q9HA82
AWRKGQALVRSLLGP	CCDC187	286	A0A096LP49
GRTQPLLGSIRDLLW	ADAM15	586	Q13444
VLIGNREWLRRNGLT	ATP7B	1146	P35670
LRWTRAWRLPREGLG	ABHD11	11	Q8NFV4
AGPASRLLWIGLQRQ	CD248	76	Q9HCU0
VWLLAGRRGPRRLVD	GPR25	61	O00155
LLRLTWFLLQKPGGR	AKAP13	176	Q12802
GQSRLVPGRGLVLWL	ALPK3	21	Q96L96
NSSLLRPRVIGEWIG	C8orf34	261	Q49A92
RAVAGPALRRWLLLG	COL4A2	6	P08572
PALRRWLLLGTVTVG	COL4A2	11	P08572
RKPSLWRRLLLEQGG	ARMC5	666	Q96C12
ARWLVLAPVRSGALR	SMDT1	6	Q9H4I9
WLGGRIRDPILLQSL	BEST1	196	O76090
PVKRLRLRGDWSDTG	DCAF6	306	Q58WW2
RLAAGGPWARDIQRA	DLL3	151	Q9NYJ7
LRQSWGLLGAPIQAR	CCDC22	256	O60826
QLRGGTRLPDRLSWP	DISC1	121	Q9NRI5
ARGRWEGSAPRRLLL	DISP2	656	A7MBM2
DGRPVLRLATWNLQG	EEPD1	256	Q7L9B9
GQRALWQGRALRIPP	ARRDC2	251	Q8TBH0
AFPWLVGQGLSSRRR	ABHD16B	421	Q9H3Z7
GRGELGLRAVWELAR	ANO8	496	Q9HCE9
LAEGALRWDLPRVQG	AP4M1	356	O00189
LRWDLPRVQGGSQLS	AP4M1	361	O00189
VRRQPRALDLSWTGV	FBXL19	481	Q6PCT2
REARVQLTPLAARWG	ISLR2	496	Q6UXK2
IVEGLLNISWGLRRP	RASSF2	51	P50749
RLWGPLEVRRVGRSS	QSOX1	661	O00391
ARGQVLLLRTRPVLW	ITGAX	606	P20702
WQLGPARGDERESLR	MTCL1	946	Q9Y4B5
EGAQLRRVGWTELLP	KASH5	356	Q8N6L0
ALSIVLWRQRVRGAP	LY6G6F	251	Q5SQ64
DVQGTRLLRLRNPWG	CAPN15	726	O75808
LTGPRSQWVLRGAEV	OBSL1	131	O75147
PEGRQGRLLGRWKAL	BCAN	886	Q96GW7
RRGILEVWSTQQGPR	RAB3GAP2	471	Q9H2M9
WDGSEVLRRIRGPLL	PATL1	126	Q86TB9
RRGLGTPRLQLWLLL	PCDHA11	6	Q9Y5I1
AVRWLGLRSRLGQPL	PTCD3	6	Q96EY7
VRARWPGLLRAAQAA	KLHL33	36	A6NCF5
LGGLKWRDSRQVPTR	KLHL34	576	Q8N239
ALPAGSSLRQRLWRA	KCND1	161	Q9NSA2
SRRRQILHLGLPWGN	KIAA0100	1056	Q14667
GLWGRLRFARKPISI	KCNQ1	186	P51787
LLGGFEQVDLIRPWR	MDN1	2101	Q9NU22
RGWRRLAQEPLGLEV	NOP53	46	Q9NZM5
ARAPSGKVRRWDQGL	FLII	466	Q13045
RGDVLAAWSGIRPLV	GPD2	391	P43304
SLPWRVVIGRLGRLG	MED13L	1891	Q71F56
RFVLLAQSRPGWLGV	MTARC1	11	Q5VT66
ERLRGRETLLPWSGL	IRAK2	501	O43187
DQAPEGRGWRRLAEL	MALT1	46	Q9UDY8
GNRTWGRLTEDPRLK	MGAT4B	86	Q9UQ53
LGRALEGLERWLPII	NUDT19	281	A8MXV4
VLPGERLVRNGVSWS	MERTK	956	Q12866
LFQWRLLGAVRGLPD	GPC5	36	P78333
RRKGPAVWGLRAQID	MTO1	116	Q9Y2Z2
VTWRRGDGQPLGLRL	HMCN2	816	Q8NDA2
ENLAGWRPRGDSLIL	KIF1B	1476	O60333
NRGLRVPFGREVWLD	FREM2	76	Q5SZK8
GIINSLLREWKGPRT	HECTD2	211	Q5U5R9
VPRTALLGERWRAGD	KIAA1614	266	Q5VZ46
RIQLPWDSVGRLEVG	HMGCS2	116	P54868
KNIWGGPITLDRIRT	PCNX2	1846	A6NKB5
LLSIVGRQRASPGWQ	PDPR	6	Q8NCN5
RRPLLGASNQALARW	EPX	156	P11678
RWQALPALRERELGS	DCAF8	151	Q5TAQ9
LNQPARLTLGRWERA	DDX28	76	Q9NUL7
RLTLGRWERAPLASQ	DDX28	81	Q9NUL7
GLDALLTQGVRPRRW	PRAMEF15	86	P0DUQ1
LRVGDLVIVVTGWRP	PKLR	546	P30613
RAVLGRWPLEEFRLG	LRRC14B	51	A6NHZ5
IETPGIRARSARLQW	LRPPRC	911	P42704
LRLLTWVIGTGSPRL	GCN1	1041	Q92616
ITGPLIRILGDRFSW	GCN1	2306	Q92616
RRLGAWLRDPGGQRL	AMH	116	P03971
RLGNRWAEIAKLLPG	MYB	161	P10242
LREVPLWVFGLRGLE	LRRC8E	496	Q6NSJ5
RVRWVSPQGRLLGNS	LRFN3	326	Q9BTN0
EGRPWRAALRVLSAL	MROH6	166	A6NGR9
GLHLELRGPQLWARR	IRF7	356	Q92985
EGIAEWLRRRVGPSA	PDIA2	141	Q13087
PARTLRLWGPRSLGV	GAL3ST4	6	Q96RP7
WQGRLEPVRLLLRAS	CASKIN2	91	Q8WXE0
GEAFRPLGRLEQLWL	LRIT1	76	Q9P2V4
RNTRIRWRQTGPILG	RELN	646	P78509
PGRGDFRIWNSQLVR	NOS3	236	P29474
IEAWDGGRPRRTGLL	DCHS2	266	Q6V1P9
RRPWDREAGTLQVLG	PLD4	21	Q96BZ4
RLGRLPTVRVGWNEI	BECN2	271	A8MW95
WAQLRAELGPRRLRG	GAL3ST2	291	Q9H3Q3
NLVKIGERPWRLVRG	GASK1B	171	Q6UWH4
GARLDVRDAWGRLPV	CDKN2A	101	P42771
GLLGPAKRDAWLQLR	EYA4	501	O95677
ILREIWRTGQPDLLG	EVA1B	131	Q9NVM1
RRWFGDDGRILALPN	CC2D2A	341	Q9P2K1
PERGRLRGWLEGSLA	DACT3	11	Q96B18
LALRVGAELRRWPLG	GLYCTK	426	Q8IVS8
PAGSLRELGVWRSLL	C2CD2L	56	O14523
ITTPNRLLRIWNDGR	GABRG1	161	Q8N1C3
TLRRGLGLQRQSPWA	CROCC2	1296	H7BZ55
PRLWRTIRLTGETIN	FBXL7	151	Q9UJT9
APGERRRLGVLATAW	HACD1	61	B0YJ81
LLRPGGILAVLRVLW	COMTD1	201	Q86VU5
LLGRLPWRVASGARR	GDF5-AS1	26	Q5U4N7
GRSVEGRPLWVLRLT	CPD	86	O75976
LLGDRPRWQRLLGED	ANKRD9	251	Q96BM1
RLGRVGWLQRLQESL	SLC1A6	16	P48664
DLWRGDLWRGLPRVR	C1QTNF8	46	P60827
ILWRLGAELQPGGRQ	CSF3R	61	Q99062
DVLDLRGSNWVPRRG	EIF4G1	981	Q04637
NSPIIWRELLDRGGK	MDH1B	61	Q5I0G3
RSSLFLWVRPNGRVG	GP1BA	606	P07359
WRPEDLGRLLGEVQA	HSF4	131	Q9ULV5
GRDRSWVIGSPEILR	MAST2	891	Q6P0Q8
LRGEGTLRLSWDQPA	ITIH6	1166	Q6UXX5
PGALWGLDRVTFRRI	PRKAR2B	241	P31323
LRLVGQLKRVPRTGW	HDDC2	21	Q7Z4H3
QRLPRAALGVTWGLD	HCFC1R1	16	Q9NWW0
FRRWLGLPAGVLITR	CLPB	236	Q9H078
GRAGWRLLQLRCLPV	COQ9	11	O75208
IVPLDWNGEGRIGLR	CNTNAP2	161	Q9UHC6
LLSLWRQSSGRGRLP	CYP2C18	16	P33260
TLQLGRALRPRGLWG	HYAL1	186	Q12794
FGRGALIRLNIWPAV	CD164L2	36	Q6UWJ8
RRLVQWGPGLVALQE	EML3	536	Q32P44
PVARDGAGLQAAWRR	EME2	281	A4GXA9
SGTSVILLDRRRPQW	SDR42E2	56	A6NKP2
WEQQRLAGRLPRGST	HDAC7	451	Q8WUI4
LAPGDLGRTRALRWV	CHADL	536	Q6NUI6
GRAAVVPLGTWRRLS	EBP	51	Q15125
AGERLWLLSLRPEGL	ETV3L	296	Q6ZN32
LLIPREVRLAGGVWR	CCDC8	11	Q9H0W5
PLGLLRTRVTWRNGL	SLC22A31	326	A6NKX4
GPRRWRRAAGAAVLL	SLC15A3	26	Q8IY34
PGGSSWRRIALLILA	SLC39A11	186	Q8N1S5
ALLAWLRSPRGRQAL	KIFC2	126	Q96AC6
RLGNRWAEIAKLLPG	MYBL1	156	P10243
WRRGLGLEPTALARR	IRGQ	516	Q8WZA9
GLQDRWLRRLQAEPG	LIPT2	21	A6NK58
RRPATGGDRELLQWL	INSL3	56	P51460
KLGRRWGPNVQRLAC	JARID2	616	Q92833
RIVGGWDLLPRALLS	IL4I1	261	Q96RQ9
QELAELFLGPGRWQR	RTL1	1161	A6NKG5
AGTFRDLRLRLWPQG	RXFP4	321	Q8TDU9
LKTPVGRGRAWLRLA	RUFY3	156	Q7L099
LIQDNPGLRRAWKRL	TAS2R39	311	P59534
LILGNPGLRRAWKRF	TAS2R40	296	P59535
VQGDPRELRLWARGD	SORL1	51	Q92673
QRRAEELRNTGPWGL	ERVW-1	426	Q9UQF0
GALWKGRPLSVRLAR	TRMT2A	131	Q8IZ69
PLSETARRGQKAGWR	RPGRIP1	96	Q96KN7
SSPGQRGRLALQWRQ	LRTM2	6	Q8N967
PGRAWGRQRLLQDRL	PLEKHA4	416	Q9H4M7
LGISLTRWPDGRNFL	PNPLA5	116	Q7Z6Z6
RGSPAEWGQRLLLVL	GPR108	11	Q9NPR9
VGRLRGRAVPVWDVL	EPPK1	2526	P58107
LRGRAVPVWDVLASG	EPPK1	3596	P58107
LRGRAVPVWDVLASG	EPPK1	4666	P58107
RGRRPLWLAVGGLLI	SLCO5A1	191	Q9H2Y9
LPLLWGRERAEGQTS	SIGLEC9	6	Q9Y336
LLIPRTRGLLSGWAR	PROZ	291	P22891
PLWSNILLRLGFERG	PKHD1	551	P08F94
APWTLPGGRQRLIRK	SCRIB	591	Q14160
SRLSLWGIQRLIQPG	STARD9	1421	Q9P2P6
VGNRIRADGRWPLVI	IQANK1	421	A8MXQ7
QLEGWRWSRPGDRIL	TFCP2L1	116	Q9NZI6
IRQVLAALLPVTGRW	RIPK4	286	P57078
GRSLWQQPSVGDILR	URB1	1581	O60287
RLNDRRTPLGELNWI	RPTOR	301	Q8N122
NSALGPRRLRASWLV	ABCB9	71	Q9NP78
LTSQLLRAVPWAGGR	AURKAIP1	6	Q9NWT8
SRRGWRLQAVAVGLP	APOBR	736	Q0VD83
SAELGLRQPAWLRGR	CHST3	351	Q7LGC8
PRIRRGIRGGLEWLK	CLCNKB	26	P51801
ASPAGEWRALLRLRL	CNNM3	91	Q8NE01
RWTLALAPRALGLSR	CNNM3	246	Q8NE01
LRDVSRREGALGWAP	ZBED3	196	Q96IU2
AGPAWLRGLRILVAD	TECTA	761	O75443
TNEGLIPVRVRRSWL	SPATA31A3	741	Q5VYP0
PIRPRNASDGLLVRW	TULP1	436	O00294
GLDALLNLGVRPRRW	PRAMEF4	86	O60810
GSVRLWRLRGGVLRS	WDR90	526	Q96KV7
RLLGEPRWGQASSDR	ZNF48	96	Q96MX3
GILEGSVRNSLWRPA	TRIM13	36	O60858
WLLRGLTLGTAPRRA	MSRB2	6	Q9Y3D2
TNEGLIPVRVRRSWL	SPATA31A1	741	Q5TZJ5
VQGLRAWGRGLRVPT	REX1BD	66	Q96EN9
QMLSSLLVRWGRPRG	TMEM158	81	Q8WZ71
GRVVSLSTPIIWRRG	TSPYL1	346	Q9H0U9
GPGVRRDTLTEQLRW	PLCH2	1291	O75038
RRSSRGRDWGLLPLL	TUT1	581	Q9H6E5
RSWGTPQLRLRVLSE	WDR97	1426	A6NE52
GLDALLTQGVRPRRW	PRAMEF9	86	P0DUQ2
RSLGLQLPDGQRREW	PFAS	406	O15067
QLAREPRLGLDLGWN	ZNF408	16	Q9H9D4
ELARLVGARPGLIWI	TEDC1	476	Q86SX3
PWQRRGLLRAQGLRG	SUGP2	676	Q8IX01
LRELGSVPLRLTWQG	MTHFSD	326	Q2M296
QVRLRLVAVRPGWSG	NEURL1B	81	A8MQ27
NLELVTRIIRDGGPW	ZNF654	151	Q8IZM8
GLDALLTQGVRPRRW	PRAMEF11	86	O60813
PGLNPTLGWRERLRA	ST7L	21	Q8TDW4
TLGWRERLRAGLAGT	ST7L	26	Q8TDW4
RWALGVIAAEAPRRG	TRIM72	356	Q6ZMU5
RVRGNLIALSVWPGT	PKHD1L1	3381	Q86WI1
GREPEGVWNLLSIVR	ZSWIM8	341	A7E2V4
VLLGRLWRRLHGRPG	STARD7	56	Q9NQZ5
SVRLAQLLSRPGWRS	VPS33A	496	Q96AX1
LGRLELWAPARQGSL	WNT9B	256	O14905
SLARGWPRGLSKLQV	VRTN	546	Q9H8Y1
ALRLWDVRGLRGAPR	WDR86	336	Q86TI4
GTWLGTHRPLARLRR	PSPN	46	O60542
DVGQRLRRGTPWLRV	TYMP	426	P19971
TFVRRLGPQGWRLVQ	TERT	26	O14746
GGPVLQTWLQDLLRR	TRPM4	126	Q8TD43
VLLDTRTGLVLRGWP	WDR81	1811	Q562E7
TRLGGPVQALIAREW	ZFTA	466	C9JLR9
VGVGLWLVISSLPRR	TMEM249	96	Q2WGJ8
TGPLRQVIEELGGWR	KEL	166	P23276
RAWRGLRERGEVVPL	KIAA2013	71	Q8IYS2
LRLGGAEPRLLRWDL	JPH3	681	Q8WXH2
IGEAVGLQPTRWSLR	PRKCH	16	P24723
LPSVRWVLGDGTQIR	MXRA5	2076	Q9NR99
PGRRILNLLRGWREP	NAPSA	36	O96009