Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	extracellular matrix structural constituent	THSD4 COL7A1 FBN1 FBN2 VWF FN1 LAMB1 LAMB2 PAPLN FBN3	6.50e-09	188	84	10	GO:0005201
GeneOntologyMolecularFunction	metalloendopeptidase activity	MEP1A PMPCA ADAMTS2 ADAMTS7 ADAMTS9 ADAMTS20 PAPPA ADAM12	4.00e-08	120	84	8	GO:0004222
GeneOntologyMolecularFunction	low-density lipoprotein particle receptor activity	LRP1 LRP1B SORL1 STAB1	5.10e-07	16	84	4	GO:0005041
GeneOntologyMolecularFunction	lipoprotein particle receptor activity	LRP1 LRP1B SORL1 STAB1	1.65e-06	21	84	4	GO:0030228
GeneOntologyMolecularFunction	metallopeptidase activity	MEP1A PMPCA ADAMTS2 ADAMTS7 ADAMTS9 ADAMTS20 PAPPA ADAM12	2.00e-06	200	84	8	GO:0008237
GeneOntologyMolecularFunction	zinc ion binding	MEP1A ZSWIM8 PDE2A ZMYND11 HIVEP1 DHX58 ADAMTS2 ADAMTS9 ZPR1 POLR2A MIB1 ADAMTS20 PAPPA ARIH1 RNF217	4.09e-06	891	84	15	GO:0008270
GeneOntologyMolecularFunction	GAF domain binding	PDE2A AIP	1.75e-05	2	84	2	GO:0036004
GeneOntologyMolecularFunction	transition metal ion binding	MEP1A ZSWIM8 PDE2A ZMYND11 HIVEP1 DHX58 FN1 ADAMTS2 ADAMTS9 ZPR1 POLR2A MIB1 ADAMTS20 PAPPA ARIH1 RNF217	3.10e-05	1189	84	16	GO:0046914
GeneOntologyMolecularFunction	structural constituent of synapse-associated extracellular matrix	LAMB1 LAMB2	5.23e-05	3	84	2	GO:0150043
GeneOntologyMolecularFunction	RNA-dependent RNA polymerase activity	POLR2A POLR2B	5.23e-05	3	84	2	GO:0003968
GeneOntologyMolecularFunction	endopeptidase activity	MEP1A PMPCA ADAMTS2 ADAMTS7 ADAMTS9 ADAMTS20 PAPPA ADAM12	4.52e-04	430	84	8	GO:0004175
GeneOntologyMolecularFunction	cargo receptor activity	LRP1 LRP1B SORL1 STAB1	4.55e-04	85	84	4	GO:0038024
GeneOntologyMolecularFunction	integrin binding	FBN1 VWF FN1 LAMB1 LAMB2	8.62e-04	175	84	5	GO:0005178
GeneOntologyMolecularFunction	RNA polymerase II activity	POLR2A POLR2B	9.38e-04	11	84	2	GO:0001055
GeneOntologyMolecularFunction	extracellular matrix constituent conferring elasticity	FBN1 FBN2	1.12e-03	12	84	2	GO:0030023
GeneOntologyMolecularFunction	calcium ion binding	FBN1 FBN2 ITLN1 LRP1 LRP4 VWCE LRP1B FBN3 NOTCH1 STAB1	1.17e-03	749	84	10	GO:0005509
GeneOntologyMolecularFunction	structural molecule activity conferring elasticity	FBN1 FBN2	1.54e-03	14	84	2	GO:0097493
GeneOntologyMolecularFunction	low-density lipoprotein particle binding	SORL1 STAB1	2.56e-03	18	84	2	GO:0030169
GeneOntologyMolecularFunction	apolipoprotein binding	LRP1 LRP4	3.16e-03	20	84	2	GO:0034185
GeneOntologyMolecularFunction	nucleotidyltransferase activity	POLR2A POLR2B SELENOO POLN	3.89e-03	152	84	4	GO:0016779
GeneOntologyMolecularFunction	structural molecule activity	THSD4 COL7A1 FBN1 FBN2 VWF FN1 LAMB1 LAMB2 PAPLN FBN3	4.14e-03	891	84	10	GO:0005198
GeneOntologyBiologicalProcess	extracellular matrix organization	THSD4 COL7A1 ADAMTSL1 FN1 ADAMTS2 ADAMTS7 ADAMTS9 LRP1 ADAMTS20 LAMB1 LAMB2 PAPLN NOTCH1	2.96e-09	377	82	13	GO:0030198
GeneOntologyBiologicalProcess	extracellular structure organization	THSD4 COL7A1 ADAMTSL1 FN1 ADAMTS2 ADAMTS7 ADAMTS9 LRP1 ADAMTS20 LAMB1 LAMB2 PAPLN NOTCH1	3.05e-09	378	82	13	GO:0043062
GeneOntologyBiologicalProcess	external encapsulating structure organization	THSD4 COL7A1 ADAMTSL1 FN1 ADAMTS2 ADAMTS7 ADAMTS9 LRP1 ADAMTS20 LAMB1 LAMB2 PAPLN NOTCH1	3.15e-09	379	82	13	GO:0045229
GeneOntologyBiologicalProcess	RNA-templated transcription	POLR2A POLR2B	4.67e-05	3	82	2	GO:0001172
GeneOntologyBiologicalProcess	extracellular matrix assembly	THSD4 LAMB1 LAMB2 NOTCH1	8.94e-05	59	82	4	GO:0085029
GeneOntologyBiologicalProcess	sequestering of TGFbeta in extracellular matrix	FBN1 FBN2	9.32e-05	4	82	2	GO:0035583
GeneOntologyBiologicalProcess	axon extension involved in regeneration	LRP1 LAMB2	1.55e-04	5	82	2	GO:0048677
GeneOntologyBiologicalProcess	positive regulation of melanocyte differentiation	ADAMTS9 ADAMTS20	1.55e-04	5	82	2	GO:0045636
GeneOntologyBiologicalProcess	establishment of protein localization to organelle	PMPCA ZPR1 LRSAM1 AIP DNAJA1 NIPBL TNPO3 NOTCH1 SORL1	2.05e-04	515	82	9	GO:0072594
GeneOntologyBiologicalProcess	sprouting of injured axon	LRP1 LAMB2	2.32e-04	6	82	2	GO:0048682
GeneOntologyCellularComponent	extracellular matrix	THSD4 COL7A1 ADAMTSL1 FBN1 FCGBP FBN2 VWF FN1 ADAMTS2 ADAMTS7 ADAMTS9 OTOGL ITLN1 ADAMTS20 LAMB1 LAMB2 PAPLN CFP FBN3	1.04e-11	656	84	19	GO:0031012
GeneOntologyCellularComponent	external encapsulating structure	THSD4 COL7A1 ADAMTSL1 FBN1 FCGBP FBN2 VWF FN1 ADAMTS2 ADAMTS7 ADAMTS9 OTOGL ITLN1 ADAMTS20 LAMB1 LAMB2 PAPLN CFP FBN3	1.09e-11	658	84	19	GO:0030312
GeneOntologyCellularComponent	collagen-containing extracellular matrix	THSD4 COL7A1 ADAMTSL1 FBN1 FBN2 VWF FN1 ADAMTS2 ADAMTS9 ITLN1 ADAMTS20 LAMB1 LAMB2 PAPLN CFP	2.80e-09	530	84	15	GO:0062023
GeneOntologyCellularComponent	microfibril	THSD4 FBN1 FBN2 FBN3	1.69e-07	13	84	4	GO:0001527
GeneOntologyCellularComponent	basement membrane	COL7A1 FBN1 FN1 LAMB1 LAMB2 PAPLN	9.79e-06	122	84	6	GO:0005604
GeneOntologyCellularComponent	endoplasmic reticulum lumen	COL7A1 ADAMTSL1 FBN1 FN1 ADAMTS7 LAMB1 LAMB2 CFP	5.69e-05	332	84	8	GO:0005788
GeneOntologyCellularComponent	Cul3-RING ubiquitin ligase complex	ZSWIM8 KBTBD8 ARIH1	5.15e-04	39	84	3	GO:0031463
GeneOntologyCellularComponent	laminin complex	LAMB1 LAMB2	7.03e-04	10	84	2	GO:0043256
GeneOntologyCellularComponent	RNA polymerase II, core complex	POLR2A POLR2B	2.09e-03	17	84	2	GO:0005665
GeneOntologyCellularComponent	protein complex involved in cell-matrix adhesion	LAMB1 LAMB2	2.09e-03	17	84	2	GO:0098637
MousePheno	fused cornea and lens	AGAP7P AGAP4 AGAP6 AGAP1	3.72e-06	24	63	4	MP:0001307
MousePheno	abnormal aortic sinus morphology	THSD4 FBN1	2.00e-05	2	63	2	MP:0010482
MousePheno	abnormal viscerocranium morphology	FBN1 FBN2 ADAMTS2 LRP4 AGAP7P AGAP4 AGAP6 NIPBL VWDE DISP1 AGAP1	6.03e-05	593	63	11	MP:0005274
MousePheno	abnormal craniofacial morphology	COL7A1 ZMYND11 FBN1 FBN2 ADAMTS2 MIB1 LRP1 LRP4 AGAP7P AGAP4 AGAP6 NIPBL VWDE DISP1 NOTCH1 AGAP1 SORL1	8.35e-05	1372	63	17	MP:0000428
MousePheno	craniofacial phenotype	COL7A1 ZMYND11 FBN1 FBN2 ADAMTS2 MIB1 LRP1 LRP4 AGAP7P AGAP4 AGAP6 NIPBL VWDE DISP1 NOTCH1 AGAP1 SORL1	8.35e-05	1372	63	17	MP:0005382
MousePheno	abnormal tooth morphology	ADAMTS2 LRP4 AGAP7P AGAP4 AGAP6 VWDE DISP1 AGAP1	8.57e-05	318	63	8	MP:0002100
MousePheno	abnormal dental arch morphology	ADAMTS2 LRP4 AGAP7P AGAP4 AGAP6 VWDE DISP1 AGAP1	8.76e-05	319	63	8	MP:0030254
MousePheno	distended pericardium	FN1 MIB1 DISP1 NOTCH1	1.08e-04	55	63	4	MP:0000292
MousePheno	abnormal jaw morphology	FBN1 FBN2 ADAMTS2 LRP4 AGAP7P AGAP4 AGAP6 VWDE DISP1 AGAP1	1.18e-04	530	63	10	MP:0000454
MousePheno	abnormal snout morphology	ADAMTS2 AGAP7P AGAP4 AGAP6 NIPBL AGAP1 SORL1	1.50e-04	257	63	7	MP:0000443
MousePheno	abnormal skin coloration	ADAMTS9 ADAMTS20 AGAP7P AGAP4 AGAP6 AGAP1	1.65e-04	182	63	6	MP:0011239
MousePheno	failure of neuromuscular synapse postsynaptic differentiation	LRP4 LAMB2	2.96e-04	6	63	2	MP:0001055
MousePheno	failure of neuromuscular synapse presynaptic differentiation	LRP4 LAMB2	2.96e-04	6	63	2	MP:0001054
MousePheno	limbs/digits/tail phenotype	COL7A1 FBN1 FBN2 FN1 ADAMTS9 ITLN1 KBTBD8 LRP1 LRP4 ADAMTS20 LAMB1 PAPPA ARIH1 NIPBL DISP1	3.68e-04	1258	63	15	MP:0005371
MousePheno	increased total lung capacity	FBN1 ADAMTS7	4.14e-04	7	63	2	MP:0010937
MousePheno	abnormal lens development	AGAP7P AGAP4 AGAP6 AGAP1	4.16e-04	78	63	4	MP:0005545
Domain	EGF-like_dom	MEP1A FBN1 FCGBP FBN2 TENM1 LRP1 LRP4 LAMB1 LAMB2 VWCE ADAM12 LRP1B VWDE FBN3 NOTCH1 SORL1 STAB1	4.61e-16	249	81	17	IPR000742
Domain	EGF-like_CS	MEP1A FBN1 FBN2 FN1 TENM1 LRP1 LRP4 LAMB1 LAMB2 VWCE ADAM12 LRP1B VWDE FBN3 NOTCH1 SORL1 STAB1	1.01e-15	261	81	17	IPR013032
Domain	EGF	MEP1A FBN1 FCGBP FBN2 TENM1 LRP1 LRP4 LAMB1 LAMB2 VWCE LRP1B VWDE FBN3 NOTCH1 SORL1 STAB1	3.84e-15	235	81	16	SM00181
Domain	EGF_1	MEP1A FBN1 FBN2 FN1 TENM1 LRP1 LRP4 LAMB1 LAMB2 VWCE ADAM12 LRP1B VWDE FBN3 NOTCH1 STAB1	1.39e-14	255	81	16	PS00022
Domain	EGF_2	MEP1A FBN1 FBN2 TENM1 LRP1 LRP4 LAMB1 LAMB2 VWCE ADAM12 LRP1B VWDE FBN3 NOTCH1 SORL1 STAB1	2.53e-14	265	81	16	PS01186
Domain	EGF_3	MEP1A FBN1 FBN2 TENM1 LRP1 LRP4 VWCE ADAM12 LRP1B VWDE FBN3 NOTCH1 SORL1 STAB1	1.46e-12	235	81	14	PS50026
Domain	Growth_fac_rcpt_	ERBB4 FBN1 FBN2 LRP1 LRP4 LAMB1 LAMB2 VWCE LRP1B FBN3 NOTCH1 STAB1	3.24e-12	156	81	12	IPR009030
Domain	TSP_1	THSD4 ADAMTSL1 ADAMTS2 ADAMTS7 ADAMTS9 ADAMTS20 PAPLN CFP	2.81e-10	63	81	8	PF00090
Domain	TSP1	THSD4 ADAMTSL1 ADAMTS2 ADAMTS7 ADAMTS9 ADAMTS20 PAPLN CFP	3.63e-10	65	81	8	SM00209
Domain	TSP1_rpt	THSD4 ADAMTSL1 ADAMTS2 ADAMTS7 ADAMTS9 ADAMTS20 PAPLN CFP	3.63e-10	65	81	8	IPR000884
Domain	TSP1	THSD4 ADAMTSL1 ADAMTS2 ADAMTS7 ADAMTS9 ADAMTS20 PAPLN CFP	3.63e-10	65	81	8	PS50092
Domain	ADAM_spacer1	THSD4 ADAMTS2 ADAMTS7 ADAMTS9 ADAMTS20 PAPLN	5.24e-10	23	81	6	IPR010294
Domain	ADAM_spacer1	THSD4 ADAMTS2 ADAMTS7 ADAMTS9 ADAMTS20 PAPLN	5.24e-10	23	81	6	PF05986
Domain	Peptidase_M12B_ADAM-TS	ADAMTSL1 ADAMTS2 ADAMTS7 ADAMTS9 ADAMTS20 PAPLN	6.97e-10	24	81	6	IPR013273
Domain	cEGF	FBN1 FBN2 LRP1 LRP4 LRP1B FBN3	1.18e-09	26	81	6	IPR026823
Domain	cEGF	FBN1 FBN2 LRP1 LRP4 LRP1B FBN3	1.18e-09	26	81	6	PF12662
Domain	EGF_CA	FBN1 FBN2 LRP1 LRP4 VWCE LRP1B FBN3 NOTCH1 STAB1	2.82e-09	122	81	9	SM00179
Domain	EGF-like_Ca-bd_dom	FBN1 FBN2 LRP1 LRP4 VWCE LRP1B FBN3 NOTCH1 STAB1	3.26e-09	124	81	9	IPR001881
Domain	EGF_CA	FBN1 FBN2 LRP1 LRP4 VWCE LRP1B FBN3 NOTCH1	3.55e-09	86	81	8	PF07645
Domain	EGF_Ca-bd_CS	FBN1 FBN2 LRP1 LRP4 VWCE LRP1B FBN3 NOTCH1	9.30e-09	97	81	8	IPR018097
Domain	EGF_CA	FBN1 FBN2 LRP1 LRP4 VWCE LRP1B FBN3 NOTCH1	1.09e-08	99	81	8	PS01187
Domain	ASX_HYDROXYL	FBN1 FBN2 LRP1 LRP4 VWCE LRP1B FBN3 NOTCH1	1.18e-08	100	81	8	PS00010
Domain	PLAC	THSD4 ADAMTSL1 ADAMTS2 ADAMTS7 PAPLN	1.50e-08	19	81	5	PS50900
Domain	PLAC	THSD4 ADAMTSL1 ADAMTS2 ADAMTS7 PAPLN	1.50e-08	19	81	5	IPR010909
Domain	EGF-type_Asp/Asn_hydroxyl_site	FBN1 FBN2 LRP1 LRP4 VWCE LRP1B FBN3 NOTCH1	1.88e-08	106	81	8	IPR000152
Domain	MetalloPept_cat_dom	MEP1A ADAMTS2 ADAMTS7 ADAMTS9 ADAMTS20 PAPPA ADAM12	5.95e-08	81	81	7	IPR024079
Domain	-	MEP1A ADAMTS2 ADAMTS7 ADAMTS9 ADAMTS20 PAPPA ADAM12	5.95e-08	81	81	7	3.40.390.10
Domain	FBN	FBN1 FBN2 FBN3	7.86e-08	3	81	3	IPR011398
Domain	ZINC_PROTEASE	MEP1A ADAMTS2 ADAMTS7 ADAMTS9 ADAMTS20 PAPPA ADAM12	2.23e-07	98	81	7	PS00142
Domain	Ldl_recept_b	LRP1 LRP4 LRP1B SORL1	3.18e-07	14	81	4	PF00058
Domain	LDLRB	LRP1 LRP4 LRP1B SORL1	3.18e-07	14	81	4	PS51120
Domain	LY	LRP1 LRP4 LRP1B SORL1	4.32e-07	15	81	4	SM00135
Domain	LDLR_classB_rpt	LRP1 LRP4 LRP1B SORL1	4.32e-07	15	81	4	IPR000033
Domain	Peptidase_M12B_N	ADAMTS2 ADAMTS7 ADAMTS9 ADAMTS20 ADAM12	6.94e-07	39	81	5	IPR002870
Domain	Pep_M12B_propep	ADAMTS2 ADAMTS7 ADAMTS9 ADAMTS20 ADAM12	6.94e-07	39	81	5	PF01562
Domain	-	TENM1 LRP1 LRP4 LRP1B SORL1	6.94e-07	39	81	5	2.120.10.30
Domain	DISINTEGRIN_1	ADAMTS2 ADAMTS7 ADAMTS9 ADAMTS20 ADAM12	7.91e-07	40	81	5	PS00427
Domain	Reprolysin	ADAMTS2 ADAMTS7 ADAMTS9 ADAMTS20 ADAM12	7.91e-07	40	81	5	PF01421
Domain	ADAM_MEPRO	ADAMTS2 ADAMTS7 ADAMTS9 ADAMTS20 ADAM12	7.91e-07	40	81	5	PS50215
Domain	DISINTEGRIN_2	ADAMTS2 ADAMTS7 ADAMTS9 ADAMTS20 ADAM12	7.91e-07	40	81	5	PS50214
Domain	Peptidase_M12B	ADAMTS2 ADAMTS7 ADAMTS9 ADAMTS20 ADAM12	7.91e-07	40	81	5	IPR001590
Domain	Disintegrin_dom	ADAMTS2 ADAMTS7 ADAMTS9 ADAMTS20 ADAM12	8.98e-07	41	81	5	IPR001762
Domain	EGF	MEP1A LRP1 LRP4 LRP1B FBN3 NOTCH1 STAB1	1.24e-06	126	81	7	PF00008
Domain	6-blade_b-propeller_TolB-like	TENM1 LRP1 LRP4 LRP1B SORL1	1.61e-06	46	81	5	IPR011042
Domain	TB	FBN1 FBN2 FBN3	2.72e-06	7	81	3	PF00683
Domain	-	FBN1 FBN2 FBN3	4.33e-06	8	81	3	3.90.290.10
Domain	EGF_extracell	TENM1 ADAM12 LRP1B NOTCH1 STAB1	6.13e-06	60	81	5	IPR013111
Domain	EGF_2	TENM1 ADAM12 LRP1B NOTCH1 STAB1	6.13e-06	60	81	5	PF07974
Domain	TB	FBN1 FBN2 FBN3	6.48e-06	9	81	3	PS51364
Domain	TB_dom	FBN1 FBN2 FBN3	6.48e-06	9	81	3	IPR017878
Domain	ArfGap	AGAP7P AGAP4 AGAP6 AGAP1	7.18e-06	29	81	4	SM00105
Domain	ArfGap	AGAP7P AGAP4 AGAP6 AGAP1	7.18e-06	29	81	4	PF01412
Domain	ARFGAP	AGAP7P AGAP4 AGAP6 AGAP1	7.18e-06	29	81	4	PS50115
Domain	ArfGAP	AGAP7P AGAP4 AGAP6 AGAP1	7.18e-06	29	81	4	IPR001164
Domain	Pept_M12B_GON-ADAMTSs	ADAMTS9 ADAMTS20	1.86e-05	2	81	2	IPR012314
Domain	GON	ADAMTS9 ADAMTS20	1.86e-05	2	81	2	PF08685
Domain	DUF5050	LRP1 LRP1B	1.86e-05	2	81	2	IPR032485
Domain	GON	ADAMTS9 ADAMTS20	1.86e-05	2	81	2	PS51046
Domain	DUF5050	LRP1 LRP1B	1.86e-05	2	81	2	PF16472
Domain	LDLR_class-A_CS	LRP1 LRP4 LRP1B SORL1	2.66e-05	40	81	4	IPR023415
Domain	PLAC	THSD4 ADAMTSL1 PAPLN	2.76e-05	14	81	3	PF08686
Domain	VWD	FCGBP VWF VWDE	4.23e-05	16	81	3	SM00216
Domain	VWF_type-D	FCGBP VWF VWDE	4.23e-05	16	81	3	IPR001846
Domain	VWFD	FCGBP VWF VWDE	4.23e-05	16	81	3	PS51233
Domain	VWD	FCGBP VWF VWDE	4.23e-05	16	81	3	PF00094
Domain	Ldl_recept_a	LRP1 LRP4 LRP1B SORL1	4.27e-05	45	81	4	PF00057
Domain	-	LRP1 LRP4 LRP1B SORL1	4.66e-05	46	81	4	4.10.400.10
Domain	LDLRA_1	LRP1 LRP4 LRP1B SORL1	5.52e-05	48	81	4	PS01209
Domain	LAMININ_IVB	LAMB1 LAMB2	5.56e-05	3	81	2	PS51116
Domain	Laminin_IV_B	LAMB1 LAMB2	5.56e-05	3	81	2	IPR013015
Domain	LDLRA_2	LRP1 LRP4 LRP1B SORL1	6.00e-05	49	81	4	PS50068
Domain	LDrepeatLR_classA_rpt	LRP1 LRP4 LRP1B SORL1	6.00e-05	49	81	4	IPR002172
Domain	LDLa	LRP1 LRP4 LRP1B SORL1	6.00e-05	49	81	4	SM00192
Domain	VWC_out	FCGBP VWF VWCE	7.24e-05	19	81	3	SM00215
Domain	hEGF	FBN2 FBN3 NOTCH1	2.38e-04	28	81	3	PF12661
Domain	EGF_LAM_2	LAMB1 LAMB2 STAB1	2.93e-04	30	81	3	PS50027
Domain	EGF_LAM_1	LAMB1 LAMB2 STAB1	2.93e-04	30	81	3	PS01248
Domain	Notch_dom	PAPPA NOTCH1	3.85e-04	7	81	2	IPR000800
Domain	Notch	PAPPA NOTCH1	3.85e-04	7	81	2	PF00066
Domain	NL	PAPPA NOTCH1	3.85e-04	7	81	2	SM00004
Domain	Laminin_EGF	LAMB1 LAMB2 STAB1	4.65e-04	35	81	3	PF00053
Domain	EGF_Lam	LAMB1 LAMB2 STAB1	4.65e-04	35	81	3	SM00180
Domain	VWC	FCGBP VWF VWCE	5.94e-04	38	81	3	SM00214
Domain	Laminin_EGF	LAMB1 LAMB2 STAB1	5.94e-04	38	81	3	IPR002049
Domain	GAF_dom-like	PDE2A DHX58	6.56e-04	9	81	2	IPR029016
Domain	-	PDE2A DHX58	6.56e-04	9	81	2	3.30.450.40
Domain	ANK	MIB1 AGAP7P AGAP4 AGAP6 NOTCH1 AGAP1	7.76e-04	251	81	6	SM00248
Domain	VWF_dom	FCGBP VWF VWCE	7.99e-04	42	81	3	IPR001007
Domain	ANK_REPEAT	MIB1 AGAP7P AGAP4 AGAP6 NOTCH1 AGAP1	8.09e-04	253	81	6	PS50088
Domain	E3_UB_ligase_RBR	ARIH1 RNF217	8.17e-04	10	81	2	IPR031127
Domain	Ankyrin_rpt-contain_dom	MIB1 AGAP7P AGAP4 AGAP6 NOTCH1 AGAP1	8.26e-04	254	81	6	IPR020683
Domain	ANK_REP_REGION	MIB1 AGAP7P AGAP4 AGAP6 NOTCH1 AGAP1	8.26e-04	254	81	6	PS50297
Domain	Ankyrin_rpt	MIB1 AGAP7P AGAP4 AGAP6 NOTCH1 AGAP1	9.70e-04	262	81	6	IPR002110
Domain	TIL	FCGBP VWF	1.19e-03	12	81	2	PF01826
Domain	C8	FCGBP VWF	1.19e-03	12	81	2	PF08742
Domain	Unchr_dom_Cys-rich	FCGBP VWF	1.40e-03	13	81	2	IPR014853
Domain	C8	FCGBP VWF	1.40e-03	13	81	2	SM00832
Domain	IBR	ARIH1 RNF217	1.63e-03	14	81	2	SM00647
Domain	TIL_dom	FCGBP VWF	1.63e-03	14	81	2	IPR002919
Domain	IBR	ARIH1 RNF217	1.63e-03	14	81	2	PF01485
Pathway	REACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS	THSD4 ADAMTSL1 ADAMTS2 ADAMTS7 ADAMTS9 ADAMTS20 CFP	2.16e-10	39	59	7	M27417
Pathway	REACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS	THSD4 ADAMTSL1 ADAMTS2 ADAMTS7 ADAMTS9 ADAMTS20 CFP	2.16e-10	39	59	7	MM15165
Pathway	REACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS	THSD4 ADAMTSL1 ADAMTS2 ADAMTS7 ADAMTS9 ADAMTS20 CFP NOTCH1	3.50e-10	68	59	8	M27303
Pathway	REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION	COL7A1 FBN1 FBN2 VWF FN1 ADAMTS2 ADAMTS9 LRP4 LAMB1 LAMB2 ADAM12 FBN3	3.17e-09	300	59	12	M610
Pathway	REACTOME_DISEASES_OF_GLYCOSYLATION	THSD4 ADAMTSL1 GNE ADAMTS2 ADAMTS7 ADAMTS9 ADAMTS20 CFP NOTCH1	7.21e-09	143	59	9	M27275
Pathway	REACTOME_O_LINKED_GLYCOSYLATION	THSD4 ADAMTSL1 ADAMTS2 ADAMTS7 ADAMTS9 ADAMTS20 CFP	3.33e-07	109	59	7	MM15164
Pathway	REACTOME_O_LINKED_GLYCOSYLATION	THSD4 ADAMTSL1 ADAMTS2 ADAMTS7 ADAMTS9 ADAMTS20 CFP	3.78e-07	111	59	7	M27416
Pathway	REACTOME_DISEASES_OF_METABOLISM	THSD4 ADAMTSL1 GNE ADAMTS2 ADAMTS7 ADAMTS9 ADAMTS20 CFP NOTCH1	8.72e-07	250	59	9	M27554
Pathway	REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX	COL7A1 FBN1 FBN2 FN1 ADAMTS9 LAMB1 FBN3	1.82e-06	140	59	7	M587
Pathway	PID_INTEGRIN1_PATHWAY	COL7A1 FBN1 FN1 LAMB1 LAMB2	7.94e-06	66	59	5	M18
Pathway	REACTOME_MOLECULES_ASSOCIATED_WITH_ELASTIC_FIBRES	FBN1 FBN2 FN1 FBN3	1.65e-05	37	59	4	M27134
Pathway	REACTOME_ELASTIC_FIBRE_FORMATION	FBN1 FBN2 FN1 FBN3	3.32e-05	44	59	4	M26969
Pathway	REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION	COL7A1 FBN1 FBN2 VWF FN1 ADAMTS2 ADAM12	9.60e-05	258	59	7	MM14572
Pathway	WP_HYPOTHESIZED_PATHWAYS_IN_PATHOGENESIS_OF_CARDIOVASCULAR_DISEASE	FBN1 FBN2 FBN3	1.50e-04	25	59	3	M39713
Pathway	REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_TRANSPORT_AND_UPTAKE_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS	FBN1 FN1 LAMB1 LAMB2 PAPPA	1.66e-04	124	59	5	M27285
Pathway	REACTOME_MET_ACTIVATES_PTK2_SIGNALING	FN1 LAMB1 LAMB2	2.61e-04	30	59	3	M27772
Pathway	REACTOME_LAMININ_INTERACTIONS	COL7A1 LAMB1 LAMB2	2.61e-04	30	59	3	M27216
Pathway	WP_INFLAMMATORY_RESPONSE_PATHWAY	FN1 LAMB1 LAMB2	2.61e-04	30	59	3	M39641
Pathway	WP_INFLAMMATORY_RESPONSE_PATHWAY	FN1 LAMB1 LAMB2	2.61e-04	30	59	3	MM15812
Pathway	REACTOME_ECM_PROTEOGLYCANS	FN1 LRP4 LAMB1 LAMB2	2.84e-04	76	59	4	M27219
Pathway	REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS	COL7A1 FBN1 VWF FN1	2.84e-04	76	59	4	MM14867
Pathway	REACTOME_MOLECULES_ASSOCIATED_WITH_ELASTIC_FIBRES	FBN1 FBN2 FN1	3.17e-04	32	59	3	MM14854
Pathway	KEGG_ECM_RECEPTOR_INTERACTION	VWF FN1 LAMB1 LAMB2	4.16e-04	84	59	4	M7098
Pathway	REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS	COL7A1 FBN1 VWF FN1	4.35e-04	85	59	4	M16441
Pathway	REACTOME_ELASTIC_FIBRE_FORMATION	FBN1 FBN2 FN1	5.72e-04	39	59	3	MM14601
Pathway	REACTOME_MET_PROMOTES_CELL_MOTILITY	FN1 LAMB1 LAMB2	6.63e-04	41	59	3	M27778
Pathway	PID_INTEGRIN3_PATHWAY	FBN1 FN1 LAMB1	7.63e-04	43	59	3	M53
Pathway	REACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION	THSD4 COL7A1 ADAMTSL1 FBN1 DPH5 FN1 GNE ADAMTS2 ADAMTS7 ADAMTS9 KBTBD8 ADAMTS20 LAMB1 LAMB2 CFP	8.58e-04	1475	59	15	M19806
Pathway	PID_INTEGRIN4_PATHWAY	LAMB1 LAMB2	9.24e-04	11	59	2	M158
Pathway	REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX	COL7A1 FBN1 FBN2 FN1	1.31e-03	114	59	4	MM14571
Pathway	REACTOME_P130CAS_LINKAGE_TO_MAPK_SIGNALING_FOR_INTEGRINS	VWF FN1	1.75e-03	15	59	2	M12101
Pathway	REACTOME_GRB2_SOS_PROVIDES_LINKAGE_TO_MAPK_SIGNALING_FOR_INTEGRINS	VWF FN1	1.75e-03	15	59	2	M1262
Pathway	REACTOME_GRB2_SOS_PROVIDES_LINKAGE_TO_MAPK_SIGNALING_FOR_INTEGRINS	VWF FN1	1.75e-03	15	59	2	MM14959
Pathway	REACTOME_SIGNALING_BY_NOTCH1_HD_DOMAIN_MUTANTS_IN_CANCER	MIB1 NOTCH1	1.75e-03	15	59	2	M27202
Pathway	REACTOME_P130CAS_LINKAGE_TO_MAPK_SIGNALING_FOR_INTEGRINS	VWF FN1	1.75e-03	15	59	2	MM14961
Pathway	REACTOME_NON_INTEGRIN_MEMBRANE_ECM_INTERACTIONS	FN1 LAMB1 LAMB2	1.92e-03	59	59	3	M27218
Pathway	PID_NOTCH_PATHWAY	MIB1 ADAM12 NOTCH1	1.92e-03	59	59	3	M17
Pathway	PID_INTEGRIN5_PATHWAY	FBN1 FN1	2.25e-03	17	59	2	M212
Pathway	REACTOME_ESTROGEN_DEPENDENT_GENE_EXPRESSION	ERBB4 POLR2A POLR2B	2.31e-03	63	59	3	MM15613
Pathway	REACTOME_FGFR2_ALTERNATIVE_SPLICING	POLR2A POLR2B	2.52e-03	18	59	2	MM15334
Pathway	REACTOME_SIGNALING_BY_FGFR2_IIIA_TM	POLR2A POLR2B	2.81e-03	19	59	2	M27739
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	THAP4 ZSWIM8 PDE2A FBN1 VWF FN1 ADAMTS9 EIF4A2 LRSAM1 MIB1 LRP1 ZBTB47 LRP4 LAMB1 AIP ZNF439 DNAJA1 LRP1B NIPBL DSCAML1 TXNDC11 AGAP1 STAB1	3.62e-14	1285	85	23	35914814
Pubmed	Comparison of an expanded ataxia interactome with patient medical records reveals a relationship between macular degeneration and ataxia.	HIVEP1 FBN1 VWF FN1 LRSAM1 LRP1 LAMB1 LAMB2 NOTCH1 TXNDC11	3.46e-13	118	85	10	21078624
Pubmed	O-fucosylation of thrombospondin type 1 repeats restricts epithelial to mesenchymal transition (EMT) and maintains epiblast pluripotency during mouse gastrulation.	THSD4 ADAMTSL1 ADAMTS2 ADAMTS7 ADAMTS9 ADAMTS20 PAPLN CFP	1.34e-11	75	85	8	20637190
Pubmed	Heparin/heparan sulfate controls fibrillin-1, -2 and -3 self-interactions in microfibril assembly.	FBN1 FBN2 FN1 FBN3	3.32e-11	4	85	4	25034023
Pubmed	Biochemical Reduction of the Topology of the Diverse WDR76 Protein Interactome.	THSD4 FBN1 FBN2 FN1 POLR2A POLR2B LRP1 LAMB1 LAMB2 DNAJA1	1.65e-10	219	85	10	31353912
Pubmed	The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.	COL7A1 ADAMTSL1 FBN1 VWF FN1 ITLN1 LAMB1 LAMB2 PAPLN	3.29e-10	167	85	9	22159717
Pubmed	GGAPs, a new family of bifunctional GTP-binding and GTPase-activating proteins.	AGAP7P AGAP4 AGAP6 AGAP1	4.15e-09	9	85	4	12640130
Pubmed	AGAP1/AP-3-dependent endocytic recycling of M5 muscarinic receptors promotes dopamine release.	AGAP7P AGAP4 AGAP6 AGAP1	6.90e-09	10	85	4	20664521
Pubmed	Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c.	FBN1 VWF FN1 ADAMTS2 ADAMTS7 LAMB1 LAMB2 PAPPA ADAM12	1.06e-08	248	85	9	24006456
Pubmed	AGAP1, a novel binding partner of nitric oxide-sensitive guanylyl cyclase.	AGAP7P AGAP4 AGAP6 AGAP1	1.08e-08	11	85	4	15381706
Pubmed	Proteomics analysis of cardiac extracellular matrix remodeling in a porcine model of ischemia/reperfusion injury.	COL7A1 FN1 ADAMTS9 ADAMTS20 LAMB1 LAMB2	1.19e-08	64	85	6	22261194
Pubmed	Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.	COL7A1 ADAMTSL1 FBN1 FBN2 VWF FN1 LAMB1 LAMB2	1.21e-08	175	85	8	28071719
Pubmed	Protein interactome reveals converging molecular pathways among autism disorders.	ZSWIM8 HIVEP1 FBN1 VWF FN1 LRSAM1 LAMB2 AGAP7P VWCE ADAM12 NOTCH1 STAB1	1.22e-08	560	85	12	21653829
Pubmed	Insights on ADAMTS proteases and ADAMTS-like proteins from mammalian genetics.	ADAMTS2 ADAMTS7 ADAMTS9 ADAMTS20	1.62e-08	12	85	4	25770910
Pubmed	The Endosome Localized Arf-GAP AGAP1 Modulates Dendritic Spine Morphology Downstream of the Neurodevelopmental Disorder Factor Dysbindin.	AGAP7P AGAP4 AGAP6 AGAP1	2.34e-08	13	85	4	27713690
Pubmed	Normal development and fertility of knockout mice lacking the tumor suppressor gene LRP1b suggest functional compensation by LRP1.	LRP1 AIP DNAJA1 LRP1B	3.26e-08	14	85	4	15082773
Pubmed	GTP-binding protein-like domain of AGAP1 is protein binding site that allosterically regulates ArfGAP protein catalytic activity.	AGAP7P AGAP4 AGAP6 AGAP1	3.26e-08	14	85	4	22453919
Pubmed	Characterization of the Extracellular Matrix of Normal and Diseased Tissues Using Proteomics.	COL7A1 FBN1 FBN2 VWF FN1 LAMB1 LAMB2	4.35e-08	135	85	7	28675934
Pubmed	ADAMTS18-fibronectin interaction regulates the morphology of liver sinusoidal endothelial cells.	FBN1 FBN2 FN1 LAMB1	9.90e-08	18	85	4	39040056
Pubmed	Extracellular matrix signatures of human primary metastatic colon cancers and their metastases to liver.	THSD4 COL7A1 FBN1 VWF FN1 LAMB1 LAMB2	1.03e-07	153	85	7	25037231
Pubmed	Interaction of the apolipoprotein E receptors low density lipoprotein receptor-related protein and sorLA/LR11.	LRP1 LRP4 SORL1	1.40e-07	5	85	3	19047013
Pubmed	Laminin-10 and Lutheran blood group glycoproteins in adhesion of human endothelial cells.	FN1 LAMB1 LAMB2	2.80e-07	6	85	3	16236823
Pubmed	Biochemical dissection of Anosmin-1 interaction with FGFR1 and components of the extracellular matrix.	FN1 LAMB1 LAMB2	2.80e-07	6	85	3	20874775
Pubmed	ADAMTS9-Mediated Extracellular Matrix Dynamics Regulates Umbilical Cord Vascular Smooth Muscle Differentiation and Rotation.	FBN2 FN1 ADAMTS9 ADAMTS20	2.84e-07	23	85	4	26027930
Pubmed	Oncogenic functions of protein kinase D2 and D3 in regulating multiple cancer-related pathways in breast cancer.	LDHD ADAMTS7 TLE2 AGAP4 AGAP6 AGAP1	4.26e-07	116	85	6	30652415
Pubmed	Adamts18 modulates the development of the aortic arch and common carotid artery.	FBN1 FBN2 FN1 LAMB1	4.77e-07	26	85	4	34189436
Pubmed	Laminin-10/11 and fibronectin differentially prevent apoptosis induced by serum removal via phosphatidylinositol 3-kinase/Akt- and MEK1/ERK-dependent pathways.	FN1 LAMB1 LAMB2	4.90e-07	7	85	3	11891225
Pubmed	Basement membrane assembly of the integrin α8β1 ligand nephronectin requires Fraser syndrome-associated proteins.	COL7A1 FN1 LAMB1 LAMB2	7.53e-07	29	85	4	22613833
Pubmed	Putative functions of extracellular matrix glycoproteins in secondary palate morphogenesis.	FBN1 FBN2 FN1	7.82e-07	8	85	3	23055981
Pubmed	Semaphorin 3E/PlexinD1 signaling is required for cardiac ventricular compaction.	ERBB4 FN1 ADAMTS7 NOTCH1	1.13e-06	32	85	4	31434798
Pubmed	Microfibril-associated glycoprotein-2 interacts with fibrillin-1 and fibrillin-2 suggesting a role for MAGP-2 in elastic fiber assembly.	FBN1 FBN2 VWF	1.17e-06	9	85	3	12122015
Pubmed	Poglut2/3 double knockout in mice results in neonatal lethality with reduced levels of fibrillin in lung tissues.	FBN1 FBN2 FN1	1.17e-06	9	85	3	38844137
Pubmed	Transcriptome-based systematic identification of extracellular matrix proteins.	THSD4 COL7A1 LAMB1 LAMB2 PAPLN	1.51e-06	79	85	5	18757743
Pubmed	Limb- and tendon-specific Adamtsl2 deletion identifies a role for ADAMTSL2 in tendon growth in a mouse model for geleophysic dysplasia.	FBN1 FBN2 FN1	1.67e-06	10	85	3	30738849
Pubmed	ADAMTS: a novel family of extracellular matrix proteases.	ADAMTS2 ADAMTS7 ADAMTS9	1.67e-06	10	85	3	11167130
Pubmed	Adamts18 Deficiency Causes Spontaneous SMG Fibrogenesis in Adult Mice.	FBN1 FBN2 FN1 LAMB1	2.06e-06	37	85	4	34323105
Pubmed	LRP2 mediates folate uptake in the developing neural tube.	LRP1 LRP4 LRP1B	2.29e-06	11	85	3	24639464
Pubmed	Proteomic identification of common SCF ubiquitin ligase FBXO6-interacting glycoproteins in three kinds of cells.	FBN2 POLR2B LRP1 LAMB1 LAMB2 ARIH1 DNAJA1 VWDE TXNDC11 SORL1	2.57e-06	613	85	10	22268729
Pubmed	Disruption of murine Adamtsl4 results in zonular fiber detachment from the lens and in retinal pigment epithelium dedifferentiation.	FBN1 FBN2 FN1	3.05e-06	12	85	3	26405179
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	ZSWIM8 ERBB4 ZMYND11 FBN2 ATXN7L2 ZNF618 POLR2A POLR2B LRP1 LRP4 LAMB1 DNAJA1 SORL1	3.10e-06	1116	85	13	31753913
Pubmed	Impaired ADAMTS9 secretion: A potential mechanism for eye defects in Peters Plus Syndrome.	FBN2 FN1 ADAMTS9	5.03e-06	14	85	3	27687499
Pubmed	Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins.	ERBB4 ITLN1 LRP1 LRP1B NOTCH1	5.10e-06	101	85	5	23382219
Pubmed	Homo- and heterotypic fibrillin-1 and -2 interactions constitute the basis for the assembly of microfibrils.	FBN1 FBN2	5.90e-06	2	85	2	12399449
Pubmed	Fibrillin-1 and fibrillin-2 are essential for formation of thick oxytalan fibers in human nonpigmented ciliary epithelial cells in vitro.	FBN1 FBN2	5.90e-06	2	85	2	21851253
Pubmed	Fibrillin assembly requires fibronectin.	FBN1 FN1	5.90e-06	2	85	2	19037100
Pubmed	Striking differences of LDL receptor-related protein 1B expression in mouse and human.	LRP1 LRP1B	5.90e-06	2	85	2	15963947
Pubmed	Type VII collagen specifically binds fibronectin via a unique subdomain within the collagenous triple helix.	COL7A1 FN1	5.90e-06	2	85	2	7963647
Pubmed	New Evidence Supporting the Role of FBN1 in the Development of Adolescent Idiopathic Scoliosis.	FBN1 FBN2	5.90e-06	2	85	2	30044367
Pubmed	Material and mechanical properties of bones deficient for fibrillin-1 or fibrillin-2 microfibrils.	FBN1 FBN2	5.90e-06	2	85	2	21440062
Pubmed	MAGP-2 has multiple binding regions on fibrillins and has covalent periodic association with fibrillin-containing microfibrils.	FBN1 FBN2	5.90e-06	2	85	2	15131124
Pubmed	Hepatitis delta antigen binds to the clamp of RNA polymerase II and affects transcriptional fidelity.	POLR2A POLR2B	5.90e-06	2	85	2	17584298
Pubmed	Microfibril structure masks fibrillin-2 in postnatal tissues.	FBN1 FBN2	5.90e-06	2	85	2	20404337
Pubmed	Stabilin-1 mediates beneficial monocyte recruitment and tolerogenic macrophage programming during CVB3-induced viral myocarditis.	FN1 STAB1	5.90e-06	2	85	2	34968453
Pubmed	Fibrillln mutations in Marfan syndrome and related phenotypes.	FBN1 FBN2	5.90e-06	2	85	2	8791520
Pubmed	Fibrillin genes map to regions of conserved mouse/human synteny on mouse chromosomes 2 and 18.	FBN1 FBN2	5.90e-06	2	85	2	8307578
Pubmed	Developmental expression of fibrillin genes suggests heterogeneity of extracellular microfibrils.	FBN1 FBN2	5.90e-06	2	85	2	7744963
Pubmed	Fibrillin microfibrils in bone physiology.	FBN1 FBN2	5.90e-06	2	85	2	26408953
Pubmed	The C-terminal region of laminin beta chains modulates the integrin binding affinities of laminins.	LAMB1 LAMB2	5.90e-06	2	85	2	19147489
Pubmed	Arg-Gly-Asp-containing domains of fibrillins-1 and -2 distinctly regulate lung fibroblast migration.	FBN1 FBN2	5.90e-06	2	85	2	18006876
Pubmed	Rare variants in FBN1 and FBN2 are associated with severe adolescent idiopathic scoliosis.	FBN1 FBN2	5.90e-06	2	85	2	24833718
Pubmed	Exome sequencing identified new mutations in a Marfan syndrome family.	FBN1 LRP1	5.90e-06	2	85	2	24484584
Pubmed	ADAMTSL6β protein rescues fibrillin-1 microfibril disorder in a Marfan syndrome mouse model through the promotion of fibrillin-1 assembly.	THSD4 FBN1	5.90e-06	2	85	2	21880733
Pubmed	Nonselective assembly of fibrillin 1 and fibrillin 2 in the rodent ocular zonule and in cultured cells: implications for Marfan syndrome.	FBN1 FBN2	5.90e-06	2	85	2	24265020
Pubmed	In vivo studies of mutant fibrillin-1 microfibrils.	FBN1 FBN2	5.90e-06	2	85	2	20529844
Pubmed	Fibrillin-1 mutations causing Weill-Marchesani syndrome and acromicric and geleophysic dysplasias disrupt heparan sulfate interactions.	FBN1 FBN2	5.90e-06	2	85	2	23133647
Pubmed	Forced expression of laminin beta1 in podocytes prevents nephrotic syndrome in mice lacking laminin beta2, a model for Pierson syndrome.	LAMB1 LAMB2	5.90e-06	2	85	2	21876163
Pubmed	Linkage of Marfan syndrome and a phenotypically related disorder to two different fibrillin genes.	FBN1 FBN2	5.90e-06	2	85	2	1852206
Pubmed	Fibrillins can co-assemble in fibrils, but fibrillin fibril composition displays cell-specific differences.	FBN1 FBN2	5.90e-06	2	85	2	12429739
Pubmed	Insight into interactions of the von-Willebrand-factor-A-like domain 2 with the FNIII-like domain 9 of collagen VII by NMR and SPR.	COL7A1 VWF	5.90e-06	2	85	2	21570975
Pubmed	A disintegrin-like and metalloprotease (reprolysin-type) with thrombospondin type 1 motif (ADAMTS) superfamily: functions and mechanisms.	THSD4 PAPLN	5.90e-06	2	85	2	19734141
Pubmed	Further delineation of familial polycystic ovary syndrome (PCOS) via whole-exome sequencing: PCOS-related rare FBN3 and FN1 gene variants are identified.	FN1 FBN3	5.90e-06	2	85	2	35141985
Pubmed	Differences in susceptibility of inbred and outbred infant mice to enterotoxigenic Escherichia coli of bovine, porcine and human origin.	FBN2 FN1	5.90e-06	2	85	2	2179554
Pubmed	Fibrillin-1 and fibrillin-2 in human embryonic and early fetal development.	FBN1 FBN2	5.90e-06	2	85	2	12524050
Pubmed	Three-dimensional visualization of extracellular matrix networks during murine development.	FBN2 FN1	5.90e-06	2	85	2	29352963
Pubmed	Metalloprotease-disintegrin ADAM12 expression is regulated by Notch signaling via microRNA-29.	ADAM12 NOTCH1	5.90e-06	2	85	2	21518768
Pubmed	Structure and expression of fibrillin-2, a novel microfibrillar component preferentially located in elastic matrices.	FBN1 FBN2	5.90e-06	2	85	2	8120105
Pubmed	The fibrillinopathies: New insights with focus on the paradigm of opposing phenotypes for both FBN1 and FBN2.	FBN1 FBN2	5.90e-06	2	85	2	35419902
Pubmed	Fibrillin assembly: dimer formation mediated by amino-terminal sequences.	FBN1 FBN2	5.90e-06	2	85	2	10504303
Pubmed	Three novel mutations of the fibrillin-1 gene and ten single nucleotide polymorphisms of the fibrillin-3 gene in Marfan syndrome patients.	FBN1 FBN3	5.90e-06	2	85	2	15221638
Pubmed	Selective integrin subunit reduction disrupts fibronectin extracellular matrix deposition and fibrillin 1 gene expression.	FBN1 FN1	5.90e-06	2	85	2	22782528
Pubmed	The low density lipoprotein receptor-related protein mediates fibronectin catabolism and inhibits fibronectin accumulation on cell surfaces.	FN1 LRP1	5.90e-06	2	85	2	11867643
Pubmed	Characterization of ADAMTS-9 and ADAMTS-20 as a distinct ADAMTS subfamily related to Caenorhabditis elegans GON-1.	ADAMTS9 ADAMTS20	5.90e-06	2	85	2	12514189
Pubmed	RNA polymerase II acts as an RNA-dependent RNA polymerase to extend and destabilize a non-coding RNA.	POLR2A POLR2B	5.90e-06	2	85	2	23395899
Pubmed	Fibrillin-1 microfibril deposition is dependent on fibronectin assembly.	FBN1 FN1	5.90e-06	2	85	2	18653538
Pubmed	LRP1 is required for novobiocin-mediated fibronectin turnover.	FN1 LRP1	5.90e-06	2	85	2	30061663
Pubmed	Immunohistochemical expression of fibrillin-1 and fibrillin-2 during tooth development.	FBN1 FBN2	5.90e-06	2	85	2	25524144
Pubmed	Switch in Laminin β2 to Laminin β1 Isoforms During Aging Controls Endothelial Cell Functions-Brief Report.	LAMB1 LAMB2	5.90e-06	2	85	2	29599141
Pubmed	First-trimester maternal serum ADAM12-s and PAPP-A levels are altered in pregnancies conceived after assisted reproduction techniques (ART).	PAPPA ADAM12	5.90e-06	2	85	2	26697810
Pubmed	Fibrillins 1 and 2 perform partially overlapping functions during aortic development.	FBN1 FBN2	5.90e-06	2	85	2	16407178
Pubmed	Complex contributions of fibronectin to initiation and maturation of microfibrils.	FBN1 FN1	5.90e-06	2	85	2	24070235
Pubmed	ADAMTSL-6 is a novel extracellular matrix protein that binds to fibrillin-1 and promotes fibrillin-1 fibril formation.	THSD4 FBN1	5.90e-06	2	85	2	19940141
Pubmed	N-terminal domains of fibrillin 1 and fibrillin 2 direct the formation of homodimers: a possible first step in microfibril assembly.	FBN1 FBN2	5.90e-06	2	85	2	10359653
Pubmed	Plasma fibronectin supports hemostasis and regulates thrombosis.	VWF FN1	5.90e-06	2	85	2	25180602
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	COL7A1 FBN1 FBN2 LRP1 LRP4 LAMB1 LAMB2 AIP ADAM12 LRP1B NOTCH1 TXNDC11 SORL1	6.85e-06	1201	85	13	35696571
Pubmed	Comparative proteomic analysis of supportive and unsupportive extracellular matrix substrates for human embryonic stem cell maintenance.	FBN1 FBN2 FN1 LAMB1	7.02e-06	50	85	4	23658023
Pubmed	Shotgun sequencing of the human transcriptome with ORF expressed sequence tags.	ZSWIM8 COL7A1 FBN2 VWF DPH5 CDC42BPA POLR2A TENM1 STAB1	8.46e-06	552	85	9	10737800
Pubmed	Fibulin-1 is required during cardiac ventricular morphogenesis for versican cleavage, suppression of ErbB2 and Erk1/2 activation, and to attenuate trabecular cardiomyocyte proliferation.	ERBB4 ADAMTS9 ADAMTS20	9.35e-06	17	85	3	22183742
Pubmed	Integrin beta1-mediated matrix assembly and signaling are critical for the normal development and function of the kidney glomerulus.	FN1 LAMB1 LAMB2	9.35e-06	17	85	3	18082680
Pubmed	TGF-beta-1 up-regulates extra-cellular matrix production in mouse hepatoblasts.	FN1 LAMB1 LAMB2	1.12e-05	18	85	3	23041440
Pubmed	Proteolysis of fibrillin-2 microfibrils is essential for normal skeletal development.	FBN1 FBN2 FN1	1.12e-05	18	85	3	35503090
Interaction	IGFL3 interactions	FBN2 ADAMTS2 ADAMTS7 LRP4 LAMB1 LAMB2 LRP1B VWDE NOTCH1 SORL1	5.35e-13	75	83	10	int:IGFL3
Interaction	NTN5 interactions	FBN1 FBN2 LRP4 LRP1B VWDE NOTCH1 SORL1	5.08e-12	24	83	7	int:NTN5
Interaction	CFC1 interactions	THSD4 ADAMTS7 LAMB1 LAMB2 PAPLN VWDE NOTCH1 TXNDC11 SORL1	2.43e-09	126	83	9	int:CFC1
Interaction	ZFP41 interactions	FBN1 FBN2 LRP1 LRP4 ARIH1 LRP1B SORL1	3.48e-09	57	83	7	int:ZFP41
Interaction	ATXN7 interactions	FBN1 VWF ATXN7L2 FN1 LRSAM1 LAMB1 LAMB2 TXNDC11	1.59e-08	109	83	8	int:ATXN7
Interaction	ZNF74 interactions	POLR2A LRP4 VWCE NOTCH1 SORL1	2.66e-07	34	83	5	int:ZNF74
Interaction	PRG2 interactions	THSD4 ZSWIM8 FBN2 ADAMTS2 ADAMTS7 LAMB2 PAPPA VWDE NOTCH1 SORL1	2.68e-07	285	83	10	int:PRG2
Interaction	FBXO2 interactions	THSD4 FBN1 FBN2 FN1 ADAMTS7 LAMB1 LAMB2 LRP1B NOTCH1 TXNDC11 SORL1	9.60e-07	411	83	11	int:FBXO2
Interaction	ZNF224 interactions	FBN2 LRP4 LRP1B SORL1	1.23e-06	20	83	4	int:ZNF224
Interaction	WDR76 interactions	THSD4 FBN1 FBN2 FN1 POLR2A POLR2B LRP1 LAMB1 LAMB2 DNAJA1	3.87e-06	383	83	10	int:WDR76
Interaction	ANKRD36B interactions	LRP1 LRP4 AHCYL2 LRP1B SORL1	4.80e-06	60	83	5	int:ANKRD36B
Interaction	EDN3 interactions	THSD4 ADAMTS7 LAMB2 VWDE NOTCH1 SORL1	5.56e-06	108	83	6	int:EDN3
Interaction	SDF2L1 interactions	THSD4 ADAMTS2 ADAMTS7 LAMB1 LAMB2 PAPLN VWDE TXNDC11 SORL1	7.07e-06	322	83	9	int:SDF2L1
Interaction	FST interactions	FN1 LRP4 ADAM12 SORL1	8.81e-06	32	83	4	int:FST
Interaction	MSTN interactions	ADAMTS2 ADAMTS7 LAMB2 VWDE	9.99e-06	33	83	4	int:MSTN
Interaction	DUSP10 interactions	ERBB4 FBN2 FN1 LRP1 SORL1	1.10e-05	71	83	5	int:DUSP10
Interaction	NDP interactions	ADAMTS7 LRP1B VWDE SORL1	1.27e-05	35	83	4	int:NDP
Interaction	BCAN interactions	THSD4 ADAMTS7 NACC2 LAMB2	1.42e-05	36	83	4	int:BCAN
Interaction	ZNF563 interactions	LRP4 LRP1B SORL1	1.44e-05	12	83	3	int:ZNF563
Interaction	HOXA1 interactions	FBN1 VWF FN1 GNE LAMB2 CFP VWCE ADAM12 NOTCH1	1.58e-05	356	83	9	int:HOXA1
Interaction	GREM2 interactions	FBN2 AHCYL2 VWDE SORL1	1.59e-05	37	83	4	int:GREM2
Interaction	VEGFD interactions	ADAMTS7 VWDE NOTCH1 SORL1	1.77e-05	38	83	4	int:VEGFD
Interaction	LYPD6B interactions	FCGBP ADAMTS7 LAMB2 VWDE	1.97e-05	39	83	4	int:LYPD6B
Interaction	LYZL2 interactions	ADAMTS2 LAMB1 LAMB2 VWDE TXNDC11	2.66e-05	85	83	5	int:LYZL2
Interaction	SIRPD interactions	ADAMTS7 LAMB2 VWDE NOTCH1 SORL1	2.81e-05	86	83	5	int:SIRPD
Interaction	SLURP1 interactions	ADAMTS2 ADAMTS7 LAMB1 LAMB2 ARIH1 SORL1	2.88e-05	144	83	6	int:SLURP1
Interaction	ZNF408 interactions	FBN1 FBN2 LRP4 VWCE LRP1B SORL1	2.99e-05	145	83	6	int:ZNF408
Interaction	DEFB123 interactions	LRP4 LRP1B SORL1	3.63e-05	16	83	3	int:DEFB123
Interaction	ELSPBP1 interactions	THSD4 ADAMTS7 LAMB2 VWDE NOTCH1	3.90e-05	92	83	5	int:ELSPBP1
Interaction	RLN1 interactions	ADAMTS2 LAMB2 LRP1B VWDE SORL1	4.10e-05	93	83	5	int:RLN1
Interaction	C3 interactions	FN1 LRP1 PAPPA C3AR1 CFP GFM1	4.35e-05	155	83	6	int:C3
Interaction	DKK2 interactions	AHCYL2 LRP1B NOTCH1 SORL1	4.92e-05	49	83	4	int:DKK2
Interaction	FOXD4L6 interactions	FBN2 LRP1B NOTCH1 SORL1	4.92e-05	49	83	4	int:FOXD4L6
Interaction	SNAR-B2 interactions	POLR2A POLR2B	5.01e-05	3	83	2	int:SNAR-B2
Interaction	CCN6 interactions	ADAMTS7 NOTCH1 SORL1	6.22e-05	19	83	3	int:CCN6
Interaction	MFAP5 interactions	FBN1 FBN2 VWF VWDE	6.23e-05	52	83	4	int:MFAP5
Interaction	DYRK1A interactions	FBN1 FN1 ADAMTS9 LRP4 LAMB1 LRP1B DSCAML1 AARSD1 AGAP1 STAB1	8.86e-05	552	83	10	int:DYRK1A
Interaction	EN1 interactions	HIVEP1 TLE2 AHCYL2 ARIH1 NIPBL	9.15e-05	110	83	5	int:EN1
Interaction	KLK3 interactions	FN1 ADAMTS7 POLR2A VWDE	1.09e-04	60	83	4	int:KLK3
Interaction	LAMA5 interactions	MEP1A COL7A1 FBN1 LAMB1 LAMB2	1.22e-04	117	83	5	int:LAMA5
Interaction	HRG interactions	FBN1 FBN2 FN1 LRP1B	1.32e-04	63	83	4	int:HRG
Interaction	FBN2 interactions	ADAMTSL1 FBN1 FBN2 VWCE	1.50e-04	65	83	4	int:FBN2
Interaction	LYPD4 interactions	FBN2 ADAMTS2 ADAMTS7 LAMB2 VWDE	1.55e-04	123	83	5	int:LYPD4
Interaction	CACNA1A interactions	HIVEP1 VWF LRP1 LAMB1 NOTCH1	1.55e-04	123	83	5	int:CACNA1A
Interaction	FBLN2 interactions	FBN1 FN1 ARIH1 VWDE	1.59e-04	66	83	4	int:FBLN2
Interaction	FBXO6 interactions	FBN2 ADAMTS7 POLR2B LRP1 LAMB1 LAMB2 ARIH1 DNAJA1 VWDE TXNDC11 SORL1	1.68e-04	717	83	11	int:FBXO6
Interaction	CDHR4 interactions	THSD4 LAMB2 VWDE TXNDC11	1.78e-04	68	83	4	int:CDHR4
Interaction	NTF3 interactions	LRP1 LAMB1 VWDE	1.83e-04	27	83	3	int:NTF3
Interaction	FEZF1 interactions	LRP4 LRP1B SORL1	2.05e-04	28	83	3	int:FEZF1
Interaction	TAFAZZIN interactions	ADAMTS2 ADAMTS7 POLR2A LRP1B VWDE SORL1	2.14e-04	207	83	6	int:TAFAZZIN
Interaction	DLL4 interactions	MIB1 NOTCH1	2.49e-04	6	83	2	int:DLL4
Interaction	MFAP4 interactions	THSD4 ADAMTS7 TLE2 LAMB2 ISL2	2.74e-04	139	83	5	int:MFAP4
Interaction	EGFL7 interactions	FN1 GNE VWCE NOTCH1	2.88e-04	77	83	4	int:EGFL7
Interaction	TAFA3 interactions	FBN2 AHCYL2 LRP1B SORL1	3.03e-04	78	83	4	int:TAFA3
Interaction	PI15 interactions	THSD4 ADAMTS7 LAMB2 SORL1	3.84e-04	83	83	4	int:PI15
Interaction	SOST interactions	LRP4 AHCYL2 SORL1	4.01e-04	35	83	3	int:SOST
Interaction	LIMK2 interactions	CDC42BPA AIP DNAJA1 NOTCH1	4.02e-04	84	83	4	int:LIMK2
Interaction	RMC1 interactions	POLR2A POLR2B DNAJA1 NOTCH1 NMD3	4.13e-04	152	83	5	int:RMC1
Interaction	B3GLCT interactions	ADAMTSL1 PAPLN CFP	4.36e-04	36	83	3	int:B3GLCT
Interaction	NID2 interactions	GNE LYG2 LAMB1 LAMB2	4.39e-04	86	83	4	int:NID2
Interaction	ORC5 interactions	LAMB2 C3AR1 TXNDC11 STAB1	4.59e-04	87	83	4	int:ORC5
Interaction	LCOR interactions	THAP4 VWF LRP1 LRP4 AIP LRP1B	4.92e-04	242	83	6	int:LCOR
Interaction	TIMP3 interactions	ADAMTS7 VWCE LRP1B SORL1	5.22e-04	90	83	4	int:TIMP3
Interaction	LTBP1 interactions	FBN1 FBN2 FN1 VWCE	5.67e-04	92	83	4	int:LTBP1
Interaction	FSTL3 interactions	FN1 ADAM12	5.92e-04	9	83	2	int:FSTL3
Interaction	CCN2 interactions	ERBB4 LRP1 ARIH1	5.96e-04	40	83	3	int:CCN2
Interaction	TAB1 interactions	ERBB4 ZMYND11 FN1 MIB1 AARSD1 NOTCH1	6.08e-04	252	83	6	int:TAB1
Interaction	PRKD2 interactions	LDHD ADAMTS7 TLE2 AGAP4 AGAP6 AGAP1	6.34e-04	254	83	6	int:PRKD2
Interaction	CTSG interactions	ADAMTS7 LRP1 VWDE SORL1	6.40e-04	95	83	4	int:CTSG
Interaction	IGFBP4 interactions	PAPPA VWDE NOTCH1	6.41e-04	41	83	3	int:IGFBP4
Interaction	DEFB135 interactions	ADAMTS2 LRP1B VWDE	6.89e-04	42	83	3	int:DEFB135
Cytoband	9q34.3	PMPCA NACC2 NOTCH1	1.03e-03	106	85	3	9q34.3
Cytoband	10p14	ZMYND11 CELF2-AS1	1.07e-03	26	85	2	10p14
Cytoband	7q32.1	AHCYL2 TNPO3	1.52e-03	31	85	2	7q32.1
Cytoband	10q11.23	AGAP7P AGAP6	1.72e-03	33	85	2	10q11.23
Cytoband	3p21.1	COL7A1 STAB1	2.78e-03	42	85	2	3p21.1
Cytoband	15q23	THSD4 ISL2	3.05e-03	44	85	2	15q23
Cytoband	Ensembl 112 genes in cytogenetic band chr9q34	PMPCA NACC2 LINC02913 NOTCH1	3.18e-03	325	85	4	chr9q34
GeneFamily	ADAM metallopeptidases with thrombospondin type 1 motif	ADAMTS2 ADAMTS7 ADAMTS9 ADAMTS20	3.56e-07	19	58	4	50
GeneFamily	ADAMTS like	THSD4 ADAMTSL1 PAPLN	1.09e-06	7	58	3	947
GeneFamily	ArfGAPs	AGAP7P AGAP4 AGAP6 AGAP1	3.64e-06	33	58	4	395
GeneFamily	Low density lipoprotein receptors	LRP1 LRP4 LRP1B	8.76e-06	13	58	3	634
GeneFamily	X-linked mental retardation\|Rho GTPase activating proteins\|BAR-PH domain containing	AGAP4 AGAP6 AGAP1	2.06e-05	17	58	3	1291
GeneFamily	Ankyrin repeat domain containing	MIB1 AGAP7P AGAP4 AGAP6 NOTCH1 AGAP1	1.22e-04	242	58	6	403
GeneFamily	Laminin subunits	LAMB1 LAMB2	6.54e-04	12	58	2	626
GeneFamily	Fibronectin type III domain containing	COL7A1 FN1 DSCAML1 SORL1	1.73e-03	160	58	4	555
GeneFamily	RNA polymerase subunits	POLR2A POLR2B	3.88e-03	29	58	2	726
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	AGAP7P AGAP4 AGAP6 AGAP1	4.30e-03	206	58	4	682
GeneFamily	Complement system\|Sushi domain containing	C3AR1 CFP	5.94e-03	36	58	2	492
GeneFamily	Basic leucine zipper proteins\|BTB domain containing	NACC2 KBTBD8 ZBTB47	9.13e-03	134	58	3	861
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	ADAMTSL1 PAPLN DSCAML1	1.50e-02	161	58	3	593
Coexpression	NABA_MATRISOME	MEP1A THSD4 COL7A1 ADAMTSL1 FBN1 FBN2 VWF FN1 ADAMTS2 ADAMTS7 ADAMTS9 OTOGL ITLN1 ADAMTS20 LAMB1 LAMB2 PAPPA PAPLN VWCE ADAM12 VWDE	6.58e-12	1008	85	21	MM17056
Coexpression	NABA_MATRISOME	MEP1A THSD4 COL7A1 ADAMTSL1 FBN1 FBN2 VWF FN1 ADAMTS2 ADAMTS7 ADAMTS9 ITLN1 ADAMTS20 LAMB1 LAMB2 PAPPA PAPLN VWCE ADAM12 VWDE FBN3	9.17e-12	1026	85	21	M5889
Coexpression	NABA_ECM_GLYCOPROTEINS	THSD4 FBN1 FBN2 VWF FN1 OTOGL LAMB1 LAMB2 PAPLN VWCE VWDE	3.07e-11	191	85	11	MM17059
Coexpression	NABA_ECM_GLYCOPROTEINS	THSD4 FBN1 FBN2 VWF FN1 LAMB1 LAMB2 PAPLN VWCE VWDE FBN3	4.06e-11	196	85	11	M3008
Coexpression	NABA_CORE_MATRISOME	THSD4 COL7A1 FBN1 FBN2 VWF FN1 OTOGL LAMB1 LAMB2 PAPLN VWCE VWDE	7.55e-11	270	85	12	MM17057
Coexpression	NABA_CORE_MATRISOME	THSD4 COL7A1 FBN1 FBN2 VWF FN1 LAMB1 LAMB2 PAPLN VWCE VWDE FBN3	9.33e-11	275	85	12	M5884
Coexpression	THEODOROU_MAMMARY_TUMORIGENESIS	TENM1 LAMB1 AGAP7P AGAP4 AGAP6 AGAP1	2.08e-09	37	85	6	MM1121
Coexpression	NABA_ECM_REGULATORS	MEP1A ADAMTSL1 ADAMTS2 ADAMTS7 ADAMTS9 ADAMTS20 PAPPA ADAM12	1.08e-06	238	85	8	M3468
Coexpression	NABA_ECM_REGULATORS	MEP1A ADAMTSL1 ADAMTS2 ADAMTS7 ADAMTS9 ADAMTS20 PAPPA ADAM12	1.23e-06	242	85	8	MM17062
Coexpression	LINDGREN_BLADDER_CANCER_CLUSTER_3_DN	THSD4 THAP4 COL7A1 ARIH1 AARSD1 NOTCH1 SORL1	9.01e-06	226	85	7	M11238
Coexpression	GAUSSMANN_MLL_AF4_FUSION_TARGETS_F_DN	AGAP7P AGAP4 AGAP6 AGAP1	1.27e-05	44	85	4	MM485
Coexpression	DI_MARTINO_MATRISOME_HIGHLY_PROLIFERATIVE_HNSCC_TUMOR_CELL_DERIVED	COL7A1 FBN2 FN1	2.17e-05	17	85	3	M47995
Coexpression	VECCHI_GASTRIC_CANCER_ADVANCED_VS_EARLY_UP	FBN1 FN1 ADAMTS2 C3AR1 ADAM12 NIPBL	2.53e-05	178	85	6	M17079
Coexpression	HARALAMBIEVA_PBMC_M_M_R_II_AGE_11_22YO_VACCINATED_VS_UNVACCINATED_7YR_DN	LDHD VWF FN1 ADAMTS7 TENM1 LRP1 ADAM12 DSCAML1 AGAP1 SORL1 STAB1	2.69e-05	740	85	11	M41202
Coexpression	GSE360_T_GONDII_VS_B_MALAYI_LOW_DOSE_DC_DN	LRP1 LAMB2 C3AR1 ADAM12 SORL1 STAB1	4.72e-05	199	85	6	M5219
Coexpression	GSE43955_TH0_VS_TGFB_IL6_TH17_ACT_CD4_TCELL_60H_DN	FBN1 FN1 LAMB2 AIP NOTCH1 AGAP1	4.85e-05	200	85	6	M9657
Coexpression	HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION	COL7A1 FBN1 FBN2 FN1 LRP1 ADAM12	4.85e-05	200	85	6	M5930
Coexpression	DESCARTES_MAIN_FETAL_STELLATE_CELLS	ADAMTSL1 ADAMTS2 ADAMTS9 LAMB1	5.30e-05	63	85	4	M40119
Coexpression	KARLSSON_TGFB1_TARGETS_DN	POLR2A AGAP7P DNAJA1 AGAP4 AGAP6 AGAP1	6.19e-05	209	85	6	MM1058
Coexpression	TURASHVILI_BREAST_LOBULAR_CARCINOMA_VS_DUCTAL_NORMAL_UP	FBN1 FN1 LAMB1 ADAM12	7.58e-05	69	85	4	M10165
Coexpression	HALLMARK_COAGULATION	MEP1A FBN1 VWF FN1 LRP1	8.80e-05	138	85	5	M5946
Coexpression	LI_PBMC_MENACTRA_AGE_18_45YO_ANTI_DT_ANTIBODY_CORRELATION_PROFILE_3DY_UP	ADAMTS20 C3AR1 STAB1	9.10e-05	27	85	3	M40935
Coexpression	DI_MARTINO_MATRISOME_HIGHLY_PROLIFERATIVE_HNSCC	COL7A1 FBN2 FN1	9.10e-05	27	85	3	M47994
Coexpression	TURASHVILI_BREAST_LOBULAR_CARCINOMA_VS_LOBULAR_NORMAL_DN	FBN1 FN1 LAMB1 ADAM12	9.97e-05	74	85	4	M13547
Coexpression	ZHANG_UTERUS_C0_SECRETORY_STROMAL3_NPPC_HIGH_CELL	FBN1 FN1 ADAMTS2 EIF4A2 LRP1 LAMB1 ADAM12	1.14e-04	337	85	7	MM16606
Coexpression	LAKE_ADULT_KIDNEY_C17_COLLECTING_SYSTEM_PCS_STRESSED_DISSOC_SUBSET	THSD4 ERBB4 LAMB1 ARIH1 DNAJA1 LRP1B	1.32e-04	240	85	6	M39236
Coexpression	THEODOROU_MAMMARY_TUMORIGENESIS	TENM1 LAMB1 AGAP1	1.39e-04	31	85	3	M1291
Coexpression	HEBERT_MATRISOME_TNBC_LUNG_METASTASIS_TUMOR_CELL_DERIVED	COL7A1 LAMB2	1.55e-04	6	85	2	M48000
Coexpression	DEBIASI_APOPTOSIS_BY_REOVIRUS_INFECTION_DN	FBN2 PMPCA POLR2A LRP4 LAMB2 SORL1	2.81e-04	276	85	6	M3063
Coexpression	NABA_BASEMENT_MEMBRANES	LAMB1 LAMB2 PAPLN	2.98e-04	40	85	3	M5887
CoexpressionAtlas	dev lower uro neuro_e15.5_PelvicGanglion_Sox10_k-means-cluster#4_top-relative-expression-ranked_1000	ADAMTSL1 FBN1 FBN2 FN1 ADAMTS9 PAPPA ADAM12 DISP1	8.33e-06	261	83	8	gudmap_dev lower uro neuro_e15.5_PelvicGanglion_Sox10_k4_1000
CoexpressionAtlas	facebase_RNAseq_e14.5_palate_poster_nasal_Tgfbr2_WT_2500_K2	THSD4 LDHD ADAMTSL1 FBN1 FBN2 FN1 ZNF618 TLE2 SELENOO LRP1 ZBTB47 LRP4 LAMB2 PAPPA AIP TRAPPC14	1.86e-05	1228	83	16	facebase_RNAseq_e14.5_palate_poster_nasal_Tgfbr2_WT_2500_K2
CoexpressionAtlas	kidney_P3_CapMes_Crym_k-means-cluster#2_top-relative-expression-ranked_500	THSD4 FBN2 ADAMTS9 LRP4 LAMB1 NOTCH1	2.51e-05	148	83	6	gudmap_kidney_P3_CapMes_Crym_k2_500
CoexpressionAtlas	facebase_RNAseq_e14.5_palate_poster_proximal_ERK2_WT_2500_K2	COL7A1 ADAMTSL1 FBN1 FBN2 VWF CDC42BPA FN1 ADAMTS2 ADAMTS7 TLE2 LRP1 PAPPA CFP RNF217 STAB1	6.13e-05	1208	83	15	facebase_RNAseq_e14.5_palate_poster_proximal_ERK2_WT_2500_K2
CoexpressionAtlas	DevelopingKidney_e14.5 whole kidney - Wnt4 KO_emap-6674_k-means-cluster#5_top-relative-expression-ranked_1000	ADAMTSL1 HIVEP1 FBN1 FBN2 ADAMTS2 ADAMTS20 PAPPA	1.35e-04	288	83	7	gudmap_developingKidney_e14.5 whole kidney - Wnt4 KO_1000_k5
CoexpressionAtlas	dev lower uro neuro_e15.5_PelvicGanglion_Sox10_k-means-cluster#2_top-relative-expression-ranked_500	ADAMTSL1 FBN2 FN1 PAPPA DISP1	1.41e-04	127	83	5	gudmap_dev lower uro neuro_e15.5_PelvicGanglion_Sox10_k2_500
CoexpressionAtlas	Myeloid Cells, MF.Thio5.II+480lo.PC, CD115+ MHC II+ F480lo SiglecF- CD11c+, Peritoneal Cavity, avg-3	FN1 LRP1 C3AR1 CFP	1.82e-04	72	83	4	GSM605859_100
CoexpressionAtlas	dev gonad_e13.5_M_InterstitFLeydig_MafB_top-relative-expression-ranked_1000	ERBB4 FBN1 FBN2 FN1 ADAMTS2 ADAMTS9 LRP1 LAMB1 PAPPA C3AR1 ADAM12	2.05e-04	773	83	11	gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_1000
CoexpressionAtlas	dev gonad_e13.5_M_InterstitTestis_Sma_top-relative-expression-ranked_1000	ADAMTSL1 FBN1 FBN2 FN1 ADAMTS2 ADAMTS9 ZNF618 LRP1 LAMB1 ADAM12 AARSD1	2.15e-04	777	83	11	gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_1000
CoexpressionAtlas	Myeloid Cells, DC.II+480lo.PC, F4/80lo MHC II+ CD11c+ CD115+, Peritoneal Cavity, avg-3	FN1 LRP1 C3AR1 CFP	2.36e-04	77	83	4	GSM854294_100
CoexpressionAtlas	Myeloid Cells, MF.Thio5.II+480int.PC, CD115+ MHC II+ F480lo SiglecF- CD11c+, Peritoneal Cavity, avg-3	FN1 LRP1 C3AR1 CFP	2.74e-04	80	83	4	GSM605856_100
CoexpressionAtlas	Myeloid Cells, MF.Thio5.II-480int.PC, CD115+ MHCII- F480int SiglecF- CD11c+, Peritoneal Cavity, avg-3	FN1 LRP1 C3AR1 CFP	2.87e-04	81	83	4	GSM605865_100
CoexpressionAtlas	Stromal Cells, LEC.MLN, gp38+ CD31+, Lymph Node, avg-4	THSD4 PDE2A FBN1 CDC42BPA FN1 ADAMTS9 LAMB1 STAB1	3.19e-04	439	83	8	GSM777059_500
CoexpressionAtlas	Myeloid Cells, MF.Thio5.II-480hi.PC, CD115+ MHC II- F480hi Siglec F-, Peritoneal Cavity, avg-3	FN1 LRP1 C3AR1 CFP	3.30e-04	84	83	4	GSM605862_100
CoexpressionAtlas	Myeloid Cells, MF.II-480hi.PC, F4/80hi CD115hi CD11b+ MHC II- CD11c-, Peritoneal Cavity, avg-3	FN1 LRP1 C3AR1 CFP	3.61e-04	86	83	4	GSM605850_100
ToppCell	mLN-(4)_Monocyte\|mLN / shred on region, Cell_type, and subtype	FBN2 ADAMTS2 ITLN1 LRP1 LAMB2 C3AR1 CFP STAB1	4.57e-09	199	85	8	6795ff31f92580195c9db776951f99d647484d24
ToppCell	mLN-Monocyte\|mLN / Region, Cell class and subclass	FBN2 ADAMTS2 ITLN1 LRP1 LAMB2 C3AR1 CFP STAB1	4.57e-09	199	85	8	241f790cd5d8a9b2451333deecc826a673bae70a
ToppCell	mLN-Monocyte-Monocyte\|mLN / Region, Cell class and subclass	FBN2 ADAMTS2 ITLN1 LRP1 LAMB2 C3AR1 CFP STAB1	4.57e-09	199	85	8	dcee372774c169a3048bdaed3734b3215bf8ffad
ToppCell	mLN-(4)_Monocyte-(40)_Monocyte\|mLN / shred on region, Cell_type, and subtype	FBN2 ADAMTS2 ITLN1 LRP1 LAMB2 C3AR1 CFP STAB1	4.57e-09	199	85	8	bcbb1eee8d79bf670dbe113094c3a292b135ce2f
ToppCell	3'-GW_trimst-1-SmallIntestine-Mesenchymal-immature_mesenchymal_cell-Mesoderm_2_(ZEB2+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	THSD4 FBN1 FBN2 FN1 ADAMTS2 LRP1 LAMB1 ISL2	4.76e-09	200	85	8	ac8a5d71acd4d401995babd233f0d3738e8ad2a5
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL7A1 FBN1 FBN2 FN1 ADAMTS2 LAMB1 PAPPA	3.59e-08	169	85	7	c0824a93674e2bff0f09b2d2fab5bab016a2e379
ToppCell	TCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-6\|TCGA-Ovary / Sample_Type by Project: Shred V9	ADAMTSL1 FBN1 FN1 ADAMTS2 LRP1 LAMB1 ADAM12	5.13e-08	178	85	7	142879e9393e721f9b05a6bb46995c9d6d713c95
ToppCell	5'-Airway_Nasal-Mesenchymal-Fibroblastic\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL7A1 FBN1 FN1 LAMB1 PAPPA PAPLN ADAM12	5.54e-08	180	85	7	935c091bbcd6d10b81dc4731779e5bd98205c99f
ToppCell	5'-Airway_Nasal-Mesenchymal\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL7A1 FBN1 FN1 LAMB1 PAPPA PAPLN ADAM12	5.54e-08	180	85	7	3dd384b7f3d9582b8fec9fe05100e466e6218b76
ToppCell	5'-Airway_Nasal-Mesenchymal-Fibroblastic-fibroblastic_type_2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL7A1 FBN1 FN1 LAMB1 PAPPA PAPLN ADAM12	6.20e-08	183	85	7	803376f5260de83c48d4f7301278d078a32b3e6e
ToppCell	5'-Airway_Nasal-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts-Peribronchial_fibroblasts_L.2.1.3.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL7A1 FBN1 FN1 LAMB1 PAPPA PAPLN ADAM12	6.20e-08	183	85	7	6d98973098c6d20c5305bce6a83a549a7d8dbfba
ToppCell	5'-Airway_Nasal-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL7A1 FBN1 FN1 LAMB1 PAPPA PAPLN ADAM12	6.20e-08	183	85	7	cc7f5a17b40e8d901885174922e5fa8877643071
ToppCell	10x5'-GI_large-bowel-Myeloid_Monocytic\|GI_large-bowel / Manually curated celltypes from each tissue	FCGBP FBN2 FN1 ADAMTS2 LRP1 C3AR1 STAB1	7.45e-08	188	85	7	d0045fdda757d191dabc7853f6a6e99c0e97d93d
ToppCell	10x5'-GI_large-bowel-Myeloid_Monocytic-Classical_monocytes\|GI_large-bowel / Manually curated celltypes from each tissue	FCGBP FBN2 FN1 ADAMTS2 LRP1 C3AR1 STAB1	7.45e-08	188	85	7	0bcf04aa47738f43c1a87dae5dc487738ee86f8c
ToppCell	COVID-19-Heart-Fib_+_EC_+_Pericyte\|Heart / Disease (COVID-19 only), tissue and cell type	FBN1 VWF FN1 ADAMTS2 LRP1 LAMB1 AGAP1	8.61e-08	192	85	7	60b1312e84f6d6448365a952469c506c00b5fe93
ToppCell	COVID-19-Heart-Fib_2\|Heart / Disease (COVID-19 only), tissue and cell type	FBN1 FN1 ADAMTS2 LRP1 LAMB1 PAPPA ADAM12	9.24e-08	194	85	7	d91c9f2ec47319051fc398320693fddbe8bbd4d6
ToppCell	Fibroblasts\|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	FBN1 CDC42BPA FN1 ADAMTS2 LRP1 LAMB1 LAMB2	1.10e-07	199	85	7	40de6d4a31cf22efa2864f79e4ec8e2b7bfc9d4a
ToppCell	3'-GW_trimst-1-SmallIntestine-Mesenchymal-immature_mesenchymal_cell\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	THSD4 FBN1 FBN2 FN1 ADAMTS2 LRP1 ISL2	1.14e-07	200	85	7	3dacd0afe69bc16bb33336ea9ea99a9cd47731d9
ToppCell	nucseq-Immune-Hematopoietic-Granulocytic\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ADAMTS7 ZNF618 TENM1 ADAM12 LRP1B AGAP1	7.64e-07	165	85	6	37615622c736e43260c38016e7c9e565ac97a3e8
ToppCell	nucseq-Immune-Hematopoietic-Granulocytic-Mast/Basophil\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ADAMTS7 ZNF618 TENM1 ADAM12 LRP1B AGAP1	7.64e-07	165	85	6	640bb71e74a61df2fcb01ceeabe4c493ef836b21
ToppCell	nucseq-Immune-Hematopoietic\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ADAMTS7 ZNF618 TENM1 ADAM12 LRP1B AGAP1	7.64e-07	165	85	6	f3df74b5763130c71c0a482a3a23f6b22acc2892
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	OTOGL LRP1 PAPPA PAPLN ADAM12 LRP1B	9.10e-07	170	85	6	5570c0e825bca77613bf0ebde620cf744fa1cb84
ToppCell	facs-Trachea-24m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l10\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MEP1A PDE2A ERBB4 ADAMTS9 KBTBD8 NOTCH1	9.74e-07	172	85	6	c84cab89c97d647b8a256fd08e33d9102810febd
ToppCell	Endothelial-Endothelial-G\|Endothelial / shred on cell class and cell subclass (v4)	THSD4 ADAMTSL1 FN1 ZNF618 LAMB1 STAB1	9.74e-07	172	85	6	644f8e42ee8d8996f6ae50cdf874559be55509fc
ToppCell	droplet-Marrow-nan-24m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTSL1 ADAMTS9 LAMB1 C3AR1 POLN DISP1	1.19e-06	178	85	6	cc0382b0ee1e6c76522e2c86ad1425c45debab5d
ToppCell	3'_v3-bone_marrow-Myeloid_Mac-Erythrophagocytic_macrophages\|bone_marrow / Manually curated celltypes from each tissue	CDC42BPA FN1 ADAMTS2 LRSAM1 ZBTB47 C3AR1	1.27e-06	180	85	6	daf69a548ed7c6f285a6adcff00f99aa22f9d6a5
ToppCell	10x3'2.3-week_12-13-Mesenchymal_myocytic\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	ADAMTSL1 ADAMTS9 LRP4 PAPPA ADAM12 VWDE	1.31e-06	181	85	6	47dce04db3392333eb2f7b9b24c32e6740d2d02f
ToppCell	10x3'2.3-week_12-13-Mesenchymal_myocytic-stroma\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	ADAMTSL1 ADAMTS9 LRP4 PAPPA ADAM12 VWDE	1.31e-06	181	85	6	19103221c3a5a16b16378348004b2c50caee4f01
ToppCell	P28-Mesenchymal-mesenchymal_fibroblast\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	FBN1 FN1 ADAMTS2 LRP1 LRP4 LAMB1	1.31e-06	181	85	6	091e7975badd1ffa463a8ec87908be20781ecfd6
ToppCell	P28-Mesenchymal\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	FBN1 FN1 ADAMTS2 LRP1 LRP4 LAMB1	1.35e-06	182	85	6	69f9d44694fe4f55a971ae0ac5dc3e7448ee78f3
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBN2 OTOGL TENM1 ADAMTS20 LRP1B DSCAML1	1.44e-06	184	85	6	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBN2 OTOGL TENM1 ADAMTS20 LRP1B DSCAML1	1.44e-06	184	85	6	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBN2 OTOGL TENM1 ADAMTS20 LRP1B DSCAML1	1.44e-06	184	85	6	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	(0)_MSCs\|World / Cell class and subclass of bone marrow stroma cells in homeostatis	FBN1 ADAMTS2 ZNF618 TLE2 LAMB1 PAPPA	1.54e-06	186	85	6	a832c1e0035bcd559722eccf262c145deb3494c7
ToppCell	Smart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte\|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	ADAMTS2 OTOGL LRP1 ADAMTS20 LRP1B STAB1	1.54e-06	186	85	6	23b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCell	(0)_MSCs-(00)_Lepr-MSC\|World / Cell class and subclass of bone marrow stroma cells in homeostatis	FBN1 ADAMTS2 ZNF618 TLE2 LAMB1 PAPPA	1.54e-06	186	85	6	f0d156167d7cc2cd8a76e5a364233e9f2170bc01
ToppCell	droplet-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTSL1 FBN1 FBN2 ADAMTS2 LAMB1 PAPPA	1.58e-06	187	85	6	4e553721fa5598cb211f44e3226280b7e6885484
ToppCell	droplet-Pancreas-Exocrine-18m-Mesenchymal\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTSL1 FBN1 FBN2 ADAMTS2 LAMB1 PAPPA	1.58e-06	187	85	6	d36e7fc6125e7a4310499365022d38f34b757a73
ToppCell	droplet-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTSL1 FBN1 FBN2 ADAMTS2 LAMB1 PAPPA	1.58e-06	187	85	6	827eae63fabf6892a82ce7779b5f395958d3d628
ToppCell	5'-Airway_Nasal-Endothelial-Blood_vessel_EC-vein_endothelial_cell\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PDE2A ADAMTSL1 FBN1 VWF LAMB1 VWCE	1.63e-06	188	85	6	524d1d928c9386acf20e53d31894107dd7290dc7
ToppCell	5'-Airway_Nasal-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_systemic-EC_venous_systemic_L.2.2.0.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PDE2A ADAMTSL1 FBN1 VWF LAMB1 VWCE	1.63e-06	188	85	6	1b57995d70cf81212e8d46dfaf44dbaf9c7bc4d5
ToppCell	5'-Airway_Nasal-Endothelial-Blood_vessel_EC\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PDE2A ADAMTSL1 FBN1 VWF LAMB1 VWCE	1.63e-06	188	85	6	cd2d1f8e43c252dd8730a5758458ef63e7ffc836
ToppCell	5'-Airway_Nasal-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_systemic\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PDE2A ADAMTSL1 FBN1 VWF LAMB1 VWCE	1.63e-06	188	85	6	f5a2f324f3f6c5078d57130392d3f1ba74f29094
ToppCell	droplet-Limb_Muscle-nan-3m-Mesenchymal-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTSL1 FBN1 FN1 ADAMTS2 LRP1 LAMB1	1.63e-06	188	85	6	7191087d8754f5e8700e3d744cd920ee26db1e57
ToppCell	5'-Airway_Nasal-Endothelial\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PDE2A ADAMTSL1 FBN1 VWF LAMB1 VWCE	1.63e-06	188	85	6	6c9d5e4014f807149328ff4eabd5e86dfe18094d
ToppCell	10x3'2.3-week_17-19-Mesenchymal_osteo-stroma-osteochondral_precursor\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	FBN1 FN1 ADAMTS2 ADAMTS9 LAMB2 ADAM12	1.69e-06	189	85	6	1ff4f8da572bdc6356e9df9f41a7f62c81d4c570
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 ADAMTSL1 FBN1 ADAMTS2 LRP1 ADAM12	1.74e-06	190	85	6	2306aa9dbeaef3be8484a5b236605de23cd75d4c
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ADAMTS2 LRP1 LAMB1 PAPPA PAPLN ADAM12	1.74e-06	190	85	6	45df8fee00f8949937863159d7aa042e72748d9b
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 ADAMTSL1 FBN1 ADAMTS2 LRP1 ADAM12	1.74e-06	190	85	6	1f83f7f24288a3b9ab33c2e113e845dba96adc8a
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 ADAMTSL1 FBN1 ADAMTS2 LRP1 ADAM12	1.79e-06	191	85	6	a58c75e9580139fb370b498d95660f10f3a2a27b
ToppCell	droplet-Lung-3m-Mesenchymal-fibroblast\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FBN1 FN1 ADAMTS2 LRP1 LRP4 LAMB1	1.79e-06	191	85	6	44a9a6768084dafc641ad455b65862bfd4cc0cb9
ToppCell	facs-Lung-24m-Mesenchymal-fibroblast\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FBN1 FN1 ADAMTS2 LRP1 LRP4 LAMB1	1.79e-06	191	85	6	094c9d3270fc1e487ccf10fb4936af5f081f6009
ToppCell	facs-Lung-24m-Mesenchymal\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FBN1 FN1 ADAMTS2 LRP1 LRP4 LAMB1	1.79e-06	191	85	6	ba02cbdfda6a94374a6472eb88499059979af472
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 FBN1 FN1 ADAMTS2 LRP1 ADAM12	1.79e-06	191	85	6	107113b930d9ad171f1b2aa20df4567c94fae7d8
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 FBN1 FN1 ADAMTS2 LRP1 ADAM12	1.79e-06	191	85	6	bc353a79a1d11ca52bba5e3874a80d432e1a7715
ToppCell	facs-Lung-3m-Mesenchymal-fibroblast\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FBN1 FN1 ADAMTS2 LRP1 LRP4 LAMB1	1.79e-06	191	85	6	997abf0cc5873bed0372c4a333ed307fa72774d2
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 ADAMTSL1 FBN1 ADAMTS2 LRP1 ADAM12	1.85e-06	192	85	6	9093a9e94a25682d109a7f6edc256a25a61103a0
ToppCell	droplet-Kidney-nan-18m-Mesenchymal\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTSL1 FBN1 FN1 ADAMTS2 LRP1 ISL2	1.85e-06	192	85	6	38d7a24ae205ef91ed2e0f402d8022f2a9cdb243
ToppCell	facs-Pancreas-Exocrine-3m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTSL1 FBN1 FBN2 ADAMTS2 LAMB1 PAPPA	1.85e-06	192	85	6	8937a59f6bbe07f671bdabbd3707dc9c17a14cd9
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 ADAMTSL1 FBN1 ADAMTS2 LRP1 ADAM12	1.85e-06	192	85	6	9ed5d49621ec1aa01716dc369bba1450b5f015f5
ToppCell	droplet-Kidney-nan-18m-Mesenchymal-Stroma____fibroblast\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTSL1 FBN1 FN1 ADAMTS2 LRP1 ISL2	1.85e-06	192	85	6	04d155897ed075c359933080e36a4ab2150b6e9f
ToppCell	facs-Pancreas-Exocrine-3m-Mesenchymal\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTSL1 FBN1 FBN2 ADAMTS2 LAMB1 PAPPA	1.85e-06	192	85	6	e4a7f2673f801b008ca67291db2fb2b9fd2955b8
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb-3m-Mesenchymal-mesenchymal_stem_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBN1 FN1 ADAMTS2 LRP1 LAMB1 LAMB2	1.85e-06	192	85	6	beac6b3c191b11add8e39e8d04562b478ea8929e
ToppCell	facs-Pancreas-Exocrine-3m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTSL1 FBN1 FBN2 ADAMTS2 LAMB1 PAPPA	1.85e-06	192	85	6	ac1477433704573f95111eee6263b93668d2845e
ToppCell	droplet-Kidney-nan-18m-Mesenchymal-fibroblast\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTSL1 FBN1 FN1 ADAMTS2 LRP1 ISL2	1.85e-06	192	85	6	84149a5c6c3b3c9b86aed77cf8e72d99ef099fab
ToppCell	15-Trachea-Endothelial-Endothelial\|Trachea / Age, Tissue, Lineage and Cell class	PDE2A FBN1 VWF FN1 ADAMTS7 STAB1	1.90e-06	193	85	6	6ea0444fc3dc156997129387184e6418947f4b12
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 ADAMTSL1 FBN1 ADAMTS2 LRP1 ADAM12	1.90e-06	193	85	6	f1199518c3626fd29bfce65070dd21a660671213
ToppCell	kidney_cells-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PDE2A ADAMTSL1 VWF FN1 NOTCH1 STAB1	1.90e-06	193	85	6	daefbfd3a3dd1351fbe94b9abfd807db44d56c24
ToppCell	15-Trachea-Endothelial\|Trachea / Age, Tissue, Lineage and Cell class	PDE2A FBN1 VWF FN1 ADAMTS7 STAB1	1.90e-06	193	85	6	b1ebf8df2d55e2938e5a495ea68b80c4ac216dc0
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-fibroblastic\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FN1 LRP4 LAMB1 PAPPA VWCE ADAM12	1.90e-06	193	85	6	68089ba4123e2f9bea9aae0023a844b5a57bfc0e
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 ADAMTSL1 FBN1 ADAMTS2 LRP1 ADAM12	1.96e-06	194	85	6	240d122dcb9dd1ab2867503ad85869853adcacae
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 ADAMTSL1 FBN1 ADAMTS2 LRP1 ADAM12	1.96e-06	194	85	6	ae7df037592f1c20c9d32be15fe6fc3c562ebeb1
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 ADAMTSL1 FBN1 ADAMTS2 LRP1 ADAM12	2.02e-06	195	85	6	d9a5c75d31c6e8bb1e1ab7fd115ac5deb5fb1c8d
ToppCell	Smart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil\|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	ADAMTSL1 FBN1 FBN2 OTOGL LRP4 LRP1B	2.02e-06	195	85	6	d3755929ebbbf5e3afde44281e9056ddb614a291
ToppCell	Smart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic\|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	ADAMTSL1 FBN1 FBN2 OTOGL LRP4 LRP1B	2.02e-06	195	85	6	19853c654ac64b3ae3bc99841c6cb29c8aaba85c
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 ADAMTSL1 FBN1 ADAMTS2 LRP1 ADAM12	2.02e-06	195	85	6	44d7bef5f59c2c2bad1392ee6aabdaa5d7f531d9
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 ADAMTSL1 FBN1 ADAMTS2 LRP1 ADAM12	2.08e-06	196	85	6	a12dd986df65c36f248cf10815c3b8b6238613b0
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(CCL11+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FBN1 FN1 ADAMTS2 LRP1 LAMB1 PAPPA	2.08e-06	196	85	6	2ab9735aa7a7e95dcf6b0bdf0427f7b57f6349ee
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 FBN1 FN1 ADAMTS2 LRP1 ADAM12	2.08e-06	196	85	6	fa445f4240c521cf04eb2e2f79a5c55fda31209a
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 FBN1 FN1 ADAMTS2 LRP1 ADAM12	2.08e-06	196	85	6	802f61e78a9a1030a86c4a980c398a73cd4d1574
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 FBN1 FN1 ADAMTS2 LAMB1 ADAM12	2.08e-06	196	85	6	3a6c942e2907aa07b5e12dbf9019d18f7bfca507
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 ADAMTSL1 FBN1 ADAMTS2 LRP1 ADAM12	2.08e-06	196	85	6	3e6803587d8566fd08cb8b290be3b6461743d79c
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 FBN1 FN1 ADAMTS2 LAMB1 ADAM12	2.08e-06	196	85	6	bba88e91cd3e3a6f5a9b443e3a4da33c5b455e70
ToppCell	facs-Lung-nan\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTSL1 FBN1 ADAMTS2 LRP1 LAMB1 LAMB2	2.08e-06	196	85	6	b05f77f3990b662682ffeaf0e4c2fb190e0a6e65
ToppCell	facs-Lung-nan-3m\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTSL1 FBN1 ADAMTS2 LRP1 LAMB1 LAMB2	2.08e-06	196	85	6	787c6cd92035e0b1108c2c086c42a229016e476b
ToppCell	10x3'2.3-week_17-19-Endothelial-stroma-sinusoidal_EC\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	PDE2A VWF FN1 ADAMTS9 LAMB1 STAB1	2.14e-06	197	85	6	4e58bbf3ecb30b4c8199adcc04d2eb134d90de56
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 ADAMTSL1 FBN1 ADAMTS2 LRP1 ADAM12	2.14e-06	197	85	6	6d027119a5f7ca2aac1b10837e43f9a2bb54db85
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 ADAMTSL1 FBN1 ADAMTS2 LRP1 ADAM12	2.14e-06	197	85	6	b349f8e96d61a4c296af64711e11fc44459a9413
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 ADAMTSL1 FBN1 ADAMTS2 LRP1 ADAM12	2.14e-06	197	85	6	c2e390653d5dee7e731c1840cfdab41987dede9b
ToppCell	COVID-19-lung-Fibroblast\|COVID-19 / Disease (COVID-19 only), tissue and cell type	FBN1 FN1 ADAMTS2 LRP1 LAMB1 ADAM12	2.21e-06	198	85	6	3ec01a55ade5e1627258cc3cfebb2c3207a4cb43
ToppCell	COVID-19-lung-Fibroblast\|lung / Disease (COVID-19 only), tissue and cell type	FBN1 FN1 ADAMTS2 LAMB1 PAPPA ADAM12	2.21e-06	198	85	6	df3de77216f5c5d6141ec44d01c56b942f611838
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Mesenchymal\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FBN1 FBN2 FN1 LRP1 LAMB1 ISL2	2.27e-06	199	85	6	84545ced0c792bc77980a50d65e484eab648d47e
ToppCell	metastatic_Brain-Fibroblasts-FB-like_cells\|metastatic_Brain / Location, Cell class and cell subclass	FBN1 FN1 ADAMTS2 LAMB1 PAPPA ADAM12	2.27e-06	199	85	6	12133087eae9f0e9b6c13a71e8187117768e64ce
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-fibroblastic\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FBN2 FN1 LRP1 LRP4 LAMB1 PAPPA	2.27e-06	199	85	6	edba1833ef5c4ca122d7c32f97670314e005f93b
ToppCell	10x3'2.3-week_14-16-Endothelial-stroma-tip_EC\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	PDE2A ADAMTSL1 VWF FN1 ADAMTS9 LAMB1	2.27e-06	199	85	6	1c69395c9305b6ecb0a826d46c8e8ec95795ad6d
ToppCell	Bronchial-10x5prime-Endothelial-Endothelia_vascular-VE_systemic_arterial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	THSD4 VWF CDC42BPA FN1 ADAMTS9 LAMB1	2.27e-06	199	85	6	6a2943a23fdd2ec814662db7c21a0d6804a6cbbc
ToppCell	5'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FBN1 FBN2 ADAMTS7 LRP1 LRP4 LAMB1	2.27e-06	199	85	6	e78f661b40da34768469549b6e755d330be6bbd8
ToppCell	Bronchial-NucSeq-Stromal-Fibroblastic-Fibro_adventitial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ADAMTSL1 FBN1 ADAMTS2 LRP1 LAMB1 PAPPA	2.34e-06	200	85	6	ad3fdcef895400f929f2ae12ff9bd85fd46adb3a
ToppCell	Bronchial-NucSeq-Stromal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FBN1 FN1 ADAMTS2 LRP1 LAMB1 PAPPA	2.34e-06	200	85	6	389cc775c8419d90fb77cd794376d2160a7bf44e
ToppCell	10x5'v1-week_14-16-Mesenchymal_osteo-stroma-osteochondral_precursor\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	FBN1 FN1 LAMB1 LAMB2 PAPPA ADAM12	2.34e-06	200	85	6	ad3fb8ef0be45032369d1325024787fbe1dfb8d6
Computational	Adhesion molecules.	COL7A1 FBN1 FBN2 VWF FN1 LAMB1 LAMB2 ADAM12	5.20e-07	141	55	8	MODULE_122
Computational	Neighborhood of CDH11	FBN1 FN1 LAMB1	2.69e-04	25	55	3	GNF2_CDH11
Computational	Placenta genes.	FCGBP FBN2 VWF FN1 GNE TLE2 LRP1 LAMB2 STAB1	5.13e-04	463	55	9	MODULE_38
Computational	Neighborhood of EGFR	FBN2 PAPPA ADAM12	5.66e-04	32	55	3	GNF2_EGFR
Computational	DRG (dorsal root ganglia) genes.	FBN1 VWF FN1 TLE2 LRP1 LAMB1 LAMB2 STAB1	6.90e-04	384	55	8	MODULE_2
Drug	LMWH	COL7A1 ERBB4 VWF FN1 POLR2A POLR2B LRP1 LAMB1 LAMB2 PAPPA CFP POLN ADAM12	1.04e-06	663	85	13	CID000000772
Drug	kalinin	COL7A1 FN1 LRSAM1 LAMB1 LAMB2	1.93e-06	55	85	5	CID000032518
Drug	AC1L9INI	COL7A1 FN1 LAMB1 LAMB2 CFP	2.75e-06	59	85	5	CID000445839
Drug	monatepil	LRP1 LRP4 LRP1B SORL1	4.00e-06	29	85	4	CID000060810
Drug	BM165	FN1 LAMB1 LAMB2	8.11e-06	11	85	3	CID003352881
Drug	Levodopa [59-92-7]; Up 200; 20.2uM; PC3; HT_HG-U133A	CEMP1 COL7A1 ADAMTS7 TLE2 TENM1 LRP1 TNPO3	9.73e-06	199	85	7	4571_UP
Drug	2-[(1R,2R,3S,4R,5R,6S)-2-[(2R,5S)-3-[(3S,4S,5R,6S)-4,5-dihydroxy-3-(methylamino)-6-methylol-tetrahydropyran-2-yl]-4-formyl-4-hydroxy-5-methylol-tetrahydrofuran-2-yl]oxy-5-guanidino-3,4,6-trihydroxy-cyclohexyl]guanidine	FBN1 FN1 MIB1 LAMB1 LAMB2	1.49e-05	83	85	5	CID011968896
Drug	Grgds	VWF FN1 GNE LAMB1 LAMB2	1.49e-05	83	85	5	CID000123811
Drug	Sas 1	MIB1 LAMB1 LAMB2	2.72e-05	16	85	3	CID006328170
Drug	Rgd Peptide	FBN1 FBN2 VWF FN1 LAMB1 LAMB2 FBN3	3.17e-05	239	85	7	CID000104802
Drug	B-08	FBN2 GNE	4.12e-05	3	85	2	CID016086421
Drug	DB04780	VWF FN1 ADAMTS7 LAMB1 LAMB2 CFP	4.26e-05	170	85	6	CID005459389
Drug	desmosine	FBN1 FBN2 FN1 FBN3	4.61e-05	53	85	4	CID000025435
Drug	ALT-711	FN1 LAMB1 LAMB2	6.36e-05	21	85	3	CID000216304
Disease	cerebral palsy (implicated_via_orthology)	AGAP7P AGAP4 AGAP6 AGAP1	1.04e-08	10	80	4	DOID:1969 (implicated_via_orthology)
Disease	connective tissue disease (implicated_via_orthology)	FBN1 FBN2 FBN3	1.92e-08	3	80	3	DOID:65 (implicated_via_orthology)
Disease	Malignant neoplasm of breast	COL7A1 PDE2A ERBB4 VWF FN1 WDR88 OTOGL EIF4A2 KBTBD8 TENM1 CFP ADAM12 NIPBL NOTCH1 SORL1	1.71e-07	1074	80	15	C0006142
Disease	cortical thickness	THSD4 FBN1 FBN2 PMPCA ADAMTS2 ADAMTS7 ADAMTS9 LRP1 LRP4 ADAMTS20 ADAM12 AGAP1 STAB1	8.81e-06	1113	80	13	EFO_0004840
Disease	scoliosis (is_implicated_in)	FBN1 FBN2	4.34e-05	4	80	2	DOID:0060249 (is_implicated_in)
Disease	spontaneous coronary artery dissection	THSD4 FBN1 LRP1	8.17e-05	31	80	3	EFO_0010820
Disease	disease recurrence, unipolar depression, bipolar disorder, schizophrenia, sex interaction measurement	THSD4 ADAM12 LRP1B	9.87e-05	33	80	3	EFO_0003761, EFO_0004952, EFO_0008343, MONDO_0004985, MONDO_0005090
Disease	mesangial proliferative glomerulonephritis (biomarker_via_orthology)	FBN1 VWF	2.01e-04	8	80	2	DOID:4783 (biomarker_via_orthology)
Disease	cortical surface area measurement	THSD4 ADAMTSL1 FBN1 FBN2 PMPCA ADAMTS7 ADAMTS9 ADAMTS20 PAPPA ADAM12 FBN3 AGAP1	2.62e-04	1345	80	12	EFO_0010736
Disease	aortic aneurysm	FBN1 LRP1	3.22e-04	10	80	2	EFO_0001666
Disease	Familial thoracic aortic aneurysm and aortic dissection	FBN1 FBN2 NOTCH1	4.08e-04	53	80	3	C4707243
Disease	intraocular pressure measurement	FBN1 FBN2 ADAMTS2 KBTBD8 LRP4 ADAMTS20 ADAM12	4.68e-04	509	80	7	EFO_0004695
Disease	Alzheimer's disease (implicated_via_orthology)	HIVEP1 LRP1 DNAJA1	5.05e-04	57	80	3	DOID:10652 (implicated_via_orthology)
Disease	aortic measurement	THSD4 FBN1 ADAMTS7 LRP1 ADAM12	6.12e-04	251	80	5	EFO_0020865
Disease	serum dimethylarginine measurement	THSD4 ERBB4 LRP1B	6.78e-04	63	80	3	EFO_0005418
Disease	brain measurement, neuroimaging measurement	THSD4 FBN2 ADAMTS9 MIB1 ADAMTS20 PAPPA DSCAML1	7.39e-04	550	80	7	EFO_0004346, EFO_0004464
Disease	Proteinuria	VWF ADAMTS7	7.45e-04	15	80	2	HP_0000093
Disease	migraine disorder, endometriosis	ERBB4 POLR2A LRP1B	1.04e-03	73	80	3	EFO_0001065, MONDO_0005277
Disease	unipolar depression, bipolar disorder, schizophrenia, sex interaction measurement	THSD4 ADAM12 LRP1B	1.17e-03	76	80	3	EFO_0003761, EFO_0008343, MONDO_0004985, MONDO_0005090
Disease	carotid artery disease (is_marker_for)	VWF PAPPA	1.20e-03	19	80	2	DOID:3407 (is_marker_for)
Disease	taurocholate measurement	CDC42BPA ADAM12	1.34e-03	20	80	2	EFO_0010538
Disease	carotid artery intima media thickness	THSD4 FBN1 ZNF618 LRP1 LRP1B VWDE	1.41e-03	450	80	6	EFO_0007117
Disease	X-12063 measurement	ADAMTS2 OTOGL PAPPA LRP1B	1.66e-03	186	80	4	EFO_0021283
Disease	waist-hip ratio	MEP1A THSD4 ERBB4 ZMYND11 FN1 ADAMTS2 ADAMTS9 ADAMTS20 LAMB1 STAB1	1.74e-03	1226	80	10	EFO_0004343
Disease	macula measurement	FBN1 CDC42BPA ADAMTS9 SORL1	1.76e-03	189	80	4	EFO_0008375
Disease	venous thromboembolism, tissue plasminogen activator measurement	VWF LRP4	1.77e-03	23	80	2	EFO_0004286, EFO_0004791
Disease	descending aortic diameter	FBN1 ADAMTS7 LRP1	1.78e-03	88	80	3	EFO_0021788
Disease	refractive error, age at onset, Myopia	ADAMTSL1 FBN1 POLR2A DSCAML1	1.90e-03	193	80	4	EFO_0004847, HP_0000545, MONDO_0004892
Disease	Myasthenic Syndromes, Congenital	LRP4 LAMB2	1.93e-03	24	80	2	C0751882
Disease	ulcerative colitis	LDHD DPH5 ITLN1 LAMB1 NOTCH1	2.20e-03	335	80	5	EFO_0000729
Disease	response to angiotensin-converting enzyme inhibitor, response to angiotensin receptor blocker, angioedema	ADAMTSL1 VWDE	2.26e-03	26	80	2	EFO_0005325, EFO_0005532, EFO_0010735
Disease	Abnormality of refraction	ADAMTSL1 FBN1 FBN2 ADAMTS9 ADAMTS20 DSCAML1 FBN3	2.34e-03	673	80	7	HP_0000539
Disease	triacylglycerol 54:7 measurement	ZPR1 TXNDC11	2.62e-03	28	80	2	EFO_0010425

Protein segments in the cluster

Peptide	Gene	Start	Entry
SIQNMRGNAHCVDCE	AGAP4	446	Q96P64
RKAENCTAEGMVCNH	ERBB4	491	Q15303
RNMRGNSHCVDCETQ	AGAP1	616	Q9UPQ3
IEGVDSNMCCGTHVS	AARSD1	201	Q9BTE6
FGMNHDTLDRGCSCQ	ADAM12	356	O43184
DHNECATSTMCVNGV	FBN3	531	Q75N90
QQIQSVCMECQGHGE	DNAJA1	171	P31689
QNHRNVGMACSICGC	C3AR1	131	Q16581
HLMGEAGCRSCPNNS	DISP1	1466	Q96F81
VAAACSQAECMGGSQ	ATXN7L2	516	Q5T6C5
TETHDICVQGQCMAA	ADAMTS20	681	P59510
ICVQGQCMAAGCDHV	ADAMTS20	686	P59510
QCMAAGCDHVLNSSA	ADAMTS20	691	P59510
TCGHGYQMRDVKCVN	ADAMTS20	1091	P59510
CSQTCGRTGMQVRSV	ADAMTS2	926	O95450
SRSCGMGVQSAERQC	ADAMTS7	551	Q9UKP4
EGQRHCCGVAQMREH	AIP	116	O00170
CCGVAQMREHSSLGH	AIP	121	O00170
SIQNMRGNAHCVDCE	AGAP6	446	Q5VW22
IAQCHQTGCVVSIMG	POLN	726	Q7Z5Q5
IEKDGGCNHMVCRNQ	ARIH1	351	Q9Y4X5
RVIHNASIMNAVGCC	DPH5	106	Q9H2P9
AANALCAGMRVTGCN	ITLN1	246	Q8WWA0
TGSMCNINIDECAGN	NOTCH1	671	P46531
DVSKHLCMINNGGCS	LRP1B	3271	Q9NZR2
REAQMIFLNCGHVCC	LRSAM1	681	Q6UWE0
GQRACACAHGMLAED	LRP1	2176	Q07954
THAVNGCCGLQMIAL	CELF2-AS1	21	Q8N7Q2
MCISGLCQIVGCDHQ	ADAMTSL1	151	Q8N6G6
MGQACGHSILCRSQQ	PDE2A	1	O00408
GMTVVQHCVSCLGAV	NIPBL	2081	Q6KC79
NVSGGVCDDCQHNTM	LAMB1	356	P07942
EGTGQCHCRQHMVGR	LAMB2	536	P55268
VTCGLGQTMEQRTCN	CFP	271	P27918
ALRHMVLENCCGSAG	OR2C3	301	Q8N628
GSFHVCQEMQGQCSV	PAPPA	1466	Q13219
IAGTCGNHQRMFTVE	KBTBD8	486	Q8NFY9
TGIKHDGTMCDTCRQ	MIB1	76	Q86YT6
SVTCGQGRATRQVMC	ADAMTS9	1251	Q9P2N4
SLTARVCHMGVCQGQ	CEMP1	221	Q6PRD7
VAHAGCMIGNSSCGV	GNE	291	Q9Y223
MRACNSAGCGNETAQ	DSCAML1	1551	Q8TD84
RQQCTCHAGKGMVCQ	FCGBP	1606	Q9Y6R7
EEGHMLNCTCFGQGR	FN1	536	P02751
IQHCNIRCMNGGSCS	FBN1	116	P35555
CAVQGGVCVNLTHMD	LDHD	106	Q86WU2
CINCMVAVGHGSDLR	DHX58	556	Q96C10
SIQNMRGNAHCVDCE	AGAP7P	446	Q5VUJ5
TCHACIGGTNVRNEM	EIF4A2	131	Q14240
ATCDANSVMNCGIRG	LYG2	51	Q86SG7
LCTQGCELHEGRNHM	LINC02913	86	Q8NAJ2
RGFVRQEMSQHCACQ	COL7A1	2791	Q02388
IQQCSVRCMNGGTCA	FBN2	146	P35556
GICMNGHCINSEGSF	FBN2	666	P35556
CAVGGVQCQTMTVNR	GFM1	146	Q96RP9
AGGVNCETTCANLAM	OTOGL	861	Q3ZCN5
MCVGCGSQIHDQFIL	ISL2	26	Q96A47
RAHTMCIEGSQGCEN	RPUSD1	126	Q9UJJ7
HGGICDCQTSRDTTM	PMPCA	136	Q10713
FHSMVCDGIIQCRDG	SORL1	1291	Q92673
NSCIVCNMGHSNTEI	AHCYL2	471	Q96HN2
VNVKGMASCRCISGH	MEP1A	686	Q16819
VHVCNLCGIMAIANT	POLR2B	1116	P30876
QCVGFCHGVLNTDNM	SELENOO	326	Q9BVL4
IMGNGHQRSVACTNC	TENM1	1171	Q9UKZ4
QRTEGCDHMTCSQCN	RNF217	431	Q8TC41
CHQCTSLMVGLIRQG	CDC42BPA	1026	Q5VT25
TMVCNRHCENGGQCL	VWDE	1391	Q8N2E2
VIIMATNCENCGHRT	ZPR1	281	O75312
VGARSGCVNMCEQAL	ZNF618	916	Q5T7W0
EFRNCGACVTLMQGH	WDR88	306	Q6ZMY6
HINEMCQERCVDGCS	VWF	316	P04275
VCHQSGEVSMGSFCR	TRAPPC14	281	Q8WVR3
SEQECMSSCQGSLHG	PAPLN	796	O95428
ERTGRCQTCAGNMTE	POLR2A	66	P24928
CGPGMQLSADRHSCQ	VWCE	166	Q96DN2
GCSEHANCSQVGTMV	STAB1	2101	Q9NY15
SGVMHQECQIQSCEL	nan	86	Q1RN00
NVTHSRMQICDQCGK	ZBTB47	456	Q9UFB7
ICSVCRDHMAQHFNG	TNPO3	526	Q9Y5L0
HNVCELCVNQTSGGM	TXNDC11	466	Q6PKC3
NGQSEVAAHACASMC	ZSWIM8	406	A7E2V4
QTTNDGVCQSMCHDK	ZMYND11	456	Q15326
SECSKTCGLGMQHRQ	THSD4	686	Q6ZMP0
GAGVRTRSVVCMTNH	THSD4	811	Q6ZMP0
MVRQFQGHTDGASCI	TLE2	581	Q04725
SHQGRGTMFECETCR	HIVEP1	951	P15822
MVICCAAVNCSNRQG	THAP4	1	Q8WY91
NMNIRGDTGHKACEC	ZNF439	136	Q8NDP4
MVRGAVQCTCHTGYR	LRP4	371	O75096
ITRGQLMNCHLCAGV	NACC2	356	Q96BF6
VQSQMCGDCHRVEAK	NMD3	136	Q96D46