Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcessregulation of RNA splicing

SRSF9 CLK2 SRRM4 SRSF10

2.70e-05207184GO:0043484
GeneOntologyBiologicalProcessRNA splicing

SRSF9 CLK2 SRSF8 SRRM4 SRSF10

5.52e-05502185GO:0008380
GeneOntologyBiologicalProcesscellular response to misfolded protein

UBR5 DNAJC18

1.22e-0419182GO:0071218
GeneOntologyBiologicalProcessresponse to misfolded protein

UBR5 DNAJC18

1.50e-0421182GO:0051788
GeneOntologyBiologicalProcessregulation of mRNA splicing, via spliceosome

SRSF9 SRRM4 SRSF10

1.82e-04129183GO:0048024
GeneOntologyBiologicalProcessmRNA splicing, via spliceosome

SRSF9 SRSF8 SRRM4 SRSF10

2.25e-04358184GO:0000398
GeneOntologyBiologicalProcessRNA splicing, via transesterification reactions with bulged adenosine as nucleophile

SRSF9 SRSF8 SRRM4 SRSF10

2.25e-04358184GO:0000377
GeneOntologyBiologicalProcessRNA splicing, via transesterification reactions

SRSF9 SRSF8 SRRM4 SRSF10

2.35e-04362184GO:0000375
GeneOntologyBiologicalProcessnegative regulation of mRNA splicing, via spliceosome

SRSF9 SRSF10

2.68e-0428182GO:0048025
GeneOntologyBiologicalProcessnegative regulation of mRNA processing

SRSF9 SRSF10

2.88e-0429182GO:0050686
GeneOntologyBiologicalProcessregulation of mRNA processing

SRSF9 SRRM4 SRSF10

3.31e-04158183GO:0050684
GeneOntologyBiologicalProcessnegative regulation of RNA splicing

SRSF9 SRSF10

3.74e-0433182GO:0033119
GeneOntologyBiologicalProcessmRNA splice site recognition

SRSF9 SRSF10

9.29e-0452182GO:0006376
GeneOntologyBiologicalProcessmRNA processing

SRSF9 SRSF8 SRRM4 SRSF10

1.14e-03551184GO:0006397
GeneOntologyBiologicalProcessRNA processing

SRSF9 CLK2 SRSF8 SRRM4 SRSF10 DUSP11

1.27e-031500186GO:0006396
GeneOntologyBiologicalProcessalternative mRNA splicing, via spliceosome

SRSF9 SRRM4

2.13e-0379182GO:0000380
GeneOntologyCellularComponentnuclear speck

SRSF9 CLK2 SRSF8 SRSF10 DUSP11

2.50e-05431185GO:0016607
GeneOntologyCellularComponentnuclear body

SRSF9 CLK2 SRSF8 SRSF10 DUSP11

7.96e-04903185GO:0016604
DomainRRM_1

SRSF9 SRSF8 SRSF10

8.25e-04208173PF00076
DomainRRM

SRSF9 SRSF8 SRSF10

9.33e-04217173SM00360
DomainRRM_dom

SRSF9 SRSF8 SRSF10

1.06e-03227173IPR000504
DomainRRM

SRSF9 SRSF8 SRSF10

1.10e-03230173PS50102
Domain-

SRSF9 SRSF8 SRSF10

1.31e-032441733.30.70.330
DomainNucleotide-bd_a/b_plait

SRSF9 SRSF8 SRSF10

1.54e-03258173IPR012677
DomainCadherin_CS

DCHS2 PCDH18

4.33e-03109172IPR020894
DomainCadherin

DCHS2 PCDH18

4.65e-03113172PF00028
DomainCADHERIN_1

DCHS2 PCDH18

4.65e-03113172PS00232
Domain-

DCHS2 PCDH18

4.73e-031141722.60.40.60
DomainCADHERIN_2

DCHS2 PCDH18

4.73e-03114172PS50268
DomainCA

DCHS2 PCDH18

4.81e-03115172SM00112
DomainCadherin-like

DCHS2 PCDH18

4.89e-03116172IPR015919
DomainCadherin

DCHS2 PCDH18

5.06e-03118172IPR002126
PathwayWP_MRNA_PROCESSING

SRSF9 CLK2 SRSF10

7.99e-05126103M39406
PathwayKEGG_SPLICEOSOME

SRSF9 SRSF8 SRSF10

8.18e-05127103M2044
PathwayREACTOME_MRNA_SPLICING

SRSF9 SRSF8 SRSF10

3.72e-04212103M14033
PathwayREACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA

SRSF9 SRSF8 SRSF10

8.65e-04283103M13087
PathwayWP_MRNA_PROCESSING

SRSF9 CLK2 SRSF10

3.30e-03451103MM15946
Pubmed

A rational nomenclature for serine/arginine-rich protein splicing factors (SR proteins).

SRSF9 SRSF8 SRSF10

3.32e-081318320516191
Pubmed

LncRNA H19 Regulates Breast Cancer DNA Damage Response and Sensitivity to PARP Inhibitors via Binding to ILF2.

SRSF9 SRSF8 SRSF10

1.78e-072218337298108
Pubmed

PIR1, a novel phosphatase that exhibits high affinity to RNA . ribonucleoprotein complexes.

SRSF9 DUSP11

7.59e-0731829685386
Pubmed

Regulation of alternative splicing by SRrp86 and its interacting proteins.

SRSF9 SRSF8 SRSF10

3.35e-065718314559993
Pubmed

Unproductive splicing of SR genes associated with highly conserved and ultraconserved DNA elements.

SRSF8 SRSF10

3.79e-06618217361132
Pubmed

SAF-B protein couples transcription and pre-mRNA splicing to SAR/MAR elements.

SRSF9 CLK2

7.07e-0681829671816
Pubmed

Matrix-screening reveals a vast potential for direct protein-protein interactions among RNA binding proteins.

SRSF9 CLK2 SRSF8 SRRM4 SRSF10

2.62e-0572318534133714
Pubmed

The cellular EJC interactome reveals higher-order mRNP structure and an EJC-SR protein nexus.

SRSF9 SRSF8 SRSF10

8.72e-0516918323084401
Pubmed

Human Antiviral Protein IFIX Suppresses Viral Gene Expression during Herpes Simplex Virus 1 (HSV-1) Infection and Is Counteracted by Virus-induced Proteasomal Degradation.

UBR5 SRSF9 SRSF10

2.80e-0425118328077445
Pubmed

A novel class of inhibitors that target SRSF10 and promote p53-mediated cytotoxicity on human colorectal cancer cells.

CLK2 SRSF10

3.18e-045118234316707
Pubmed

The protein interaction landscape of the human CMGC kinase group.

SRSF9 CLK2 SRSF8 SRSF10

3.87e-0469518423602568
InteractionPABPC5 interactions

SRSF9 CLK2 SRSF8 SRSF10 DUSP11

1.29e-07142185int:PABPC5
InteractionSREK1 interactions

UBR5 SRSF9 SRSF8 SRRM4 SRSF10

4.55e-07183185int:SREK1
InteractionH19 interactions

SRSF9 SRSF8 SRSF10

1.73e-0627183int:H19
InteractionLUC7L interactions

UBR5 CLK2 SRSF8 SRRM4 SRSF10

1.81e-06242185int:LUC7L
InteractionMRPL4 interactions

UBR5 SRSF9 CLK2 SRSF10 DUSP11

3.56e-06278185int:MRPL4
InteractionSRSF4 interactions

UBR5 CLK2 SRSF8 SRRM4 SRSF10

5.17e-06300185int:SRSF4
InteractionAPOBEC3D interactions

CLK2 SRSF8 SRSF10 DUSP11

7.89e-06148184int:APOBEC3D
InteractionTRA2A interactions

UBR5 SRSF9 CLK2 SRSF8 SRSF10

8.21e-06330185int:TRA2A
InteractionNKAPD1 interactions

SRSF9 CLK2 SRSF8 SRSF10

1.10e-05161184int:NKAPD1
InteractionLUC7L2 interactions

UBR5 CLK2 SRSF8 SRRM4 SRSF10

1.14e-05353185int:LUC7L2
InteractionELAVL2 interactions

CLK2 SRSF8 TCF3 SRSF10

2.03e-05188184int:ELAVL2
InteractionSNIP1 interactions

SRSF9 CLK2 SRSF8 SRRM4 SRSF10

2.54e-05417185int:SNIP1
InteractionSRSF11 interactions

SRSF9 CLK2 SRRM4 SRSF10

2.74e-05203184int:SRSF11
InteractionSRSF7 interactions

SRSF9 CLK2 SRSF8 SRSF10 DUSP11

2.78e-05425185int:SRSF7
InteractionRNPS1 interactions

UBR5 SRSF9 CLK2 SRRM4 SRSF10

2.78e-05425185int:RNPS1
InteractionCLK1 interactions

CLK2 SRSF8 SRRM4 SRSF10

3.68e-05219184int:CLK1
InteractionCLK3 interactions

UBR5 CLK2 SRSF8 SRSF10

3.75e-05220184int:CLK3
InteractionMRPL44 interactions

SRSF9 TCF3 SRSF10 DUSP11

4.31e-05228184int:MRPL44
InteractionSNRPA interactions

ARHGAP23 SRSF9 CLK2 SRSF8 SRSF10

5.08e-05482185int:SNRPA
InteractionSRSF10 interactions

UBR5 SRSF9 CLK2 SRSF10

8.44e-05271184int:SRSF10
InteractionLUZP4 interactions

CLK2 SRRM4 SRSF10

8.89e-0599183int:LUZP4
InteractionGSPT2 interactions

UBR5 CLK2 SRSF10

1.12e-04107183int:GSPT2
InteractionSRSF1 interactions

UBR5 SRSF9 CLK2 TCF3 SRSF10

1.12e-04570185int:SRSF1
InteractionSAP18 interactions

UBR5 CLK2 SRSF8 SRSF10

1.33e-04305184int:SAP18
InteractionRBM39 interactions

UBR5 SRSF9 CLK2 TCF3 SRRM4 SRSF10

2.04e-041042186int:RBM39
InteractionU2AF2 interactions

UBR5 SRSF9 CLK2 SRSF8 SRSF10

2.09e-04651185int:U2AF2
InteractionTRA2B interactions

SRSF9 CLK2 SRSF8 SRSF10

3.25e-04385184int:TRA2B
InteractionSRPK2 interactions

DNAH6 SRSF9 CLK2 SRSF8 SRSF10

3.27e-04717185int:SRPK2
InteractionPRPF38A interactions

CLK2 SRSF8 SRRM4

3.74e-04161183int:PRPF38A
InteractionDYRK2 interactions

UBR5 CLK2 SRSF10

4.61e-04173183int:DYRK2
InteractionMRPL19 interactions

SRSF9 SRSF10 DUSP11

4.69e-04174183int:MRPL19
InteractionCLK2 interactions

CLK2 SRSF8 SRSF10

6.54e-04195183int:CLK2
InteractionCLK4 interactions

SRRM4 SRSF10

6.97e-0444182int:CLK4
InteractionMRPL18 interactions

SRSF9 SRSF10 DUSP11

7.04e-04200183int:MRPL18
InteractionSON interactions

UBR5 CLK2 TCF3

7.89e-04208183int:SON
InteractionZC3H11A interactions

CLK2 SRSF8 SRSF10

8.68e-04215183int:ZC3H11A
InteractionSRSF6 interactions

SRSF9 CLK2 SRSF8 SRSF10

8.88e-04503184int:SRSF6
InteractionSRSF9 interactions

SRSF9 SRSF10 DUSP11

9.77e-04224183int:SRSF9
InteractionSRSF3 interactions

SRSF9 CLK2 SRSF8 SRSF10

1.02e-03522184int:SRSF3
InteractionMXI1 interactions

UBR5 PEAR1

1.09e-0355182int:MXI1
InteractionHNRNPA1 interactions

ARHGAP23 DNAH6 SRSF9 SRSF10 DUSP11

1.15e-03945185int:HNRNPA1
InteractionU2AF1 interactions

UBR5 CLK2 SRRM4

1.18e-03239183int:U2AF1
InteractionLARP4B interactions

CLK2 SRSF8 SRSF10

1.19e-03240183int:LARP4B
InteractionPRR3 interactions

CLK2 SRSF8 DUSP11

1.28e-03246183int:PRR3
InteractionMETTL14 interactions

UBR5 SRSF9 SRSF8 SRSF10

1.31e-03558184int:METTL14
InteractionRBMS2 interactions

CLK2 SRSF10 DUSP11

1.36e-03251183int:RBMS2
InteractionSNRNP70 interactions

SRSF9 CLK2 SRSF8 SRRM4 SRSF10

1.38e-03984185int:SNRNP70
InteractionPAIP2 interactions

UBR5 SRSF9

1.42e-0363182int:PAIP2
InteractionNUP37 interactions

SRSF9 SRSF10

1.52e-0365182int:NUP37
InteractionMAGOH interactions

SRSF9 SRSF8 SRSF10

1.57e-03264183int:MAGOH
InteractionKIF23 interactions

UBR5 DNAJC18 SRSF9 SRSF8 SRSF10

1.70e-031031185int:KIF23
CytobandEnsembl 112 genes in cytogenetic band chr12q24

SRSF9 SRRM4

1.13e-02415182chr12q24
GeneFamilyRNA binding motif containing|Serine and arginine rich splicing factors

SRSF9 SRSF8 SRSF10

6.36e-0812133737
GeneFamilyRNA binding motif containing

SRSF9 SRSF10

9.89e-03213132725
CoexpressionPUJANA_ATM_PCC_NETWORK

SRSF9 CLK2 SRSF8 TCF3 SRSF10 MSH5 DUSP11

2.25e-051394187M9585
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Igfbp6_Pltp|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SORCS3 PCDH18 SRRM4

1.62e-0512418336dfc702a570e1a1a6dde09f38badf9023ea7287
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Igfbp4_Mab21l1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SORCS3 PCDH18 SRRM4

2.13e-051361839cf076597e6fd9390850fda259daa13022f15893
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Igfbp6_Pltp|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SORCS3 PCDH18 SRRM4

2.28e-051391839e9f29f92dbe65b26cc78b3a1c00778c6a701f5b
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Rspo1_Itga4|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SORCS3 PCDH18 BEAN1

2.53e-051441837de962346ba9653d90dd13bb7d977fe44d200bba
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DNAH6 SORCS3 BEAN1

3.59e-05162183373513f9d0e5007b2e10a8b78d4909dcce9e3b62
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Ptprt_Pkp2|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SORCS3 BEAN1 SRRM4

4.15e-0517018314aa86a4f526ed6986afcb28c49225522055550c
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Vip|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SORCS3 PCDH18 SRRM4

4.22e-051711835efd15300f865ebf651e0888265cbd717bc3b9d3
ToppCell10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-Pericyte-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

DCHS2 PCDH18 PEAR1

4.22e-05171183a4a2c5dc995589fbe3d4ca6ee1df888807e4ae34
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Vip|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SORCS3 PCDH18 SRRM4

4.29e-051721837e1a7700a4c2b1d100da1d6e475e73498ebb605a
ToppCellAdult-Endothelial-endothelial_cell_of_lymph_vessel-D231|Adult / Lineage, Cell type, age group and donor

DNAJC18 DCHS2 PEAR1

4.76e-05178183c80ca7a2d3f976089a5e71d0cd9ba9a1c0bd2815
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DNAH6 SORCS3 BEAN1

5.08e-05182183a8cc56f32efe180e8fb5d69dbe606a794b3db700
ToppCellEndothelial-A-Donor_04|World / lung cells shred on cell class, cell subclass, sample id

ARHGAP23 SORCS3 PEAR1

5.33e-05185183ae49c61f6ecf128fe2a958b8c75c83688da75f59
ToppCell10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-SMC_prolif-G|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

DCHS2 PCDH18 PEAR1

6.33e-05196183cb5860f580b477bfa52b22cdc21b808e1371e6e0
ToppCellNon-neuronal-Dividing-Radial_Glia-early|World / Primary Cells by Cluster

SRSF9 PCDH18 PEAR1

6.33e-05196183dd3c6ea5e4ebcc27064f16507de6db6dc8f86fa8
ToppCellNon-neuronal-Dividing-Radial_Glia-early-1|World / Primary Cells by Cluster

SRSF9 PCDH18 PEAR1

6.33e-0519618370fe6a1a6de891832aaa6276c985b326985e14db
ToppCellwk_08-11-Mesenchymal-Fibroblast-Early_fibro|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

SRSF9 PCDH18 SRSF10

6.62e-05199183d67f5ae05daf942fb79f5b962021f37f4e275f4d
ToppCellBrain_organoid-organoid_Tanaka_cellReport-1m-Neuronal-Interneuron|1m / Sample Type, Dataset, Time_group, and Cell type.

ARHGAP23 DCHS2 SRRM4

6.72e-05200183fc839e9c33ea1d4ee0f42f21fd32a54e7cbe1f5a
ToppCellEntopeduncular-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Myoc_(Myoc)-|Entopeduncular / BrainAtlas - Mouse McCarroll V32

DNAH6 MSH5

8.06e-04105182bfd3395c51a0e868aa92eac4e929de59a3fe8b50
ToppCellEntopeduncular-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Myoc_(Myoc)|Entopeduncular / BrainAtlas - Mouse McCarroll V32

DNAH6 MSH5

8.06e-0410518276b73bc9236030e0703868fa8f7ecee2affe565b
ToppCellEntopeduncular-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Myoc_(Myoc)--|Entopeduncular / BrainAtlas - Mouse McCarroll V32

DNAH6 MSH5

8.06e-0410518296566c83999aa625c84a4ed18a6df9daa99f9578
ToppCellControl-Endothelial-Endothelial-Activated_Gen_Cap|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ARHGAP23 GPR137C

1.07e-03121182a5962d1c476e6966870832b72d511607e047248b
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Igfbp6_Car10|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SORCS3 PCDH18

1.17e-03127182f808c727c0817ed10e76eaffa9493a516e9a6b50
ToppCellPBMC-Control-Hematopoietic-Platelet-Platelet-plt_5|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

GPR137C SRRM4

1.34e-0313618288b5c839d0446c6d6b7e81fc4d48f5e7e96eea11
ToppCellPBMC-Control-Hematopoietic-Platelet-Platelet-plt_5|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

GPR137C SRRM4

1.34e-0313618227a41463e6f16deb5b1d4f17fefded9959038c07
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_B-B_cell-B_c03-CD27-AIM2|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CLK2 TCF3

1.42e-03140182af9efcbaeeae69fcdac4a15fa244728b65915564
ToppCellHealthy-CD4+_T_activated|World / disease group, cell group and cell class

DNAJC18 DUSP11

1.42e-03140182407691970ec72a3afb45e431cf48814546b8acff
ToppCellPosterior_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)-Synpr|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

SORCS3 PCDH18

1.51e-0314418204f9054895be2275eecda687a6eeb02fa5ec69b9
ToppCellPosterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Bcl6|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

DNAH6 DCHS2

1.51e-0314418208005be9e3367f78ef27e125d9cce5ca53f4bd2d
ToppCellHealthy-CD4+_T_activated|Healthy / disease group, cell group and cell class

DNAJC18 DUSP11

1.53e-0314518245e8089fdf7d6f69b383816d8945e39fba24c873
ToppCell343B-Lymphocytic-CD8+_Cytotoxic_T-cell|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

GPR137C PEAR1

1.55e-03146182bb7bf20245d93c8812920dd0debbf1ed00add378
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Lect1_Oxtr|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SORCS3 PCDH18

1.61e-0314918210ffd0051fb027bbebc662ca602c80d89bbf99c6
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_B|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CLK2 TCF3

1.63e-0315018253de595376a9fc92491dfd58ff25938b0bf79903
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_B-B_cell|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CLK2 TCF3

1.63e-03150182e4b40b3243ed26d0c46bf196ac06e148834e7ed2
ToppCellPND07-28-samps-Mesenchymal-Pericyte|PND07-28-samps / Age Group, Lineage, Cell class and subclass

PCDH18 PEAR1

1.63e-031501825b111ec11a642d63fafa7e1422e36f81a2776531
ToppCellPND07-28-samps-Mesenchymal-Pericyte-pericyte_F|PND07-28-samps / Age Group, Lineage, Cell class and subclass

PCDH18 PEAR1

1.63e-031501822d0d6dc07dcfe28e3d7694c52d15d17dae2fd47b
ToppCellE18.5-samps-Mesenchymal-Pericyte-pericyte_B|E18.5-samps / Age Group, Lineage, Cell class and subclass

GPR137C PCDH18

1.65e-031511828ba15ab24fe2e71df0a2a7511ca451ad2376bd91
ToppCellE18.5-samps-Mesenchymal-Pericyte-pericyte_C|E18.5-samps / Age Group, Lineage, Cell class and subclass

PCDH18 PEAR1

1.65e-031511823f2abaa42876ce7a71d934ff16abe0cab0991a05
ToppCellPosterior_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

SORCS3 PCDH18

1.74e-03155182105d59d8a1bb8cb37eef2c1767d737b2108ac7c5
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Rspo4_Rxfp1_Chat|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SORCS3 BEAN1

1.74e-031551823b8def9e8f66511736ea37f259511f7c8b7743af
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Lect1_Oxtr|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SORCS3 PCDH18

1.74e-0315518299e749f7075e2c64e9a0bf91009f95b6969197c8
ToppCellfacs-Limb_Muscle-forelimb_and_hindlimb|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAH6 SORCS3

1.83e-03159182f7803f7b4e0379ae8256ec53110833bedee7db98
ToppCellfacs-Limb_Muscle-forelimb_and_hindlimb-18m|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAH6 SORCS3

1.83e-031591826e2d38e78d2ef7803e8bb154b5c788bf62a41045
ToppCellBrain_organoid-organoid_Velasco_nature|Brain_organoid / Sample Type, Dataset, Time_group, and Cell type.

SRSF8 SRSF10

1.88e-031611822de213169fe1965ceaea545297228117c81d9909
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SORCS3 BEAN1

1.88e-031611824bb7bae54ba3bdf46b525c01f5ad3db8e49819cb
ToppCell368C-Fibroblasts-Fibroblast-E|368C / Donor, Lineage, Cell class and subclass (all cells)

PCDH18 BEAN1

1.90e-03162182e17632778a57c71d6005d3abca3a0443a92040e7
ToppCell3'_v3-bone_marrow-Lymphocytic_B-Pre-B|bone_marrow / Manually curated celltypes from each tissue

ARHGAP23 DNAJC18

1.90e-03162182e088e66aabc307dde5d2b9aa295c34ef68155b1a
ToppCell368C-Fibroblasts-Fibroblast-E-|368C / Donor, Lineage, Cell class and subclass (all cells)

PCDH18 BEAN1

1.90e-03162182ac4a80fd72c9311ea2b3e574c6284bbce4f2756c
ToppCellIPF-Epithelial-PNEC|Epithelial / Disease state, Lineage and Cell class

PCDH18 SRRM4

1.90e-03162182865d0e215d54fb1412f00cf0649c71c2f1878e57
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell_prolif|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GPR137C PCDH18

1.92e-031631821feb4ef7b8abcfca9a72c8d13c40548de79e7db2
ToppCell5'-Adult-Appendix-Epithelial-goblet|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GPR137C DNAH6

1.94e-03164182e83b632ac7e1dace946991ddfe1fbfbbffc3a88b
ToppCell5'-Adult-Appendix-Epithelial-goblet-BEST2+_Goblet_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GPR137C DNAH6

1.94e-0316418229da0175bd3808a5b3039a6161c764105608ef96
ToppCellfacs-Kidney-nan-24m-Mesenchymal-mesangial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCDH18 SRRM4

1.97e-03165182c746bb22ef52d7f7fa6ee9c37ae6bbe0ccce718e
ToppCellfacs-Kidney-nan-24m-Mesenchymal-mesangial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCDH18 SRRM4

1.97e-031651824cdd80580d5638fd649280ba3893251c2f898f3f
ToppCellEndothelial-B-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

BEAN1 PEAR1

1.99e-03166182c286987ea4e511195607c87ec4529c2c2ed2122e
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Arhgap36_Hmcn1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SORCS3 SRRM4

2.02e-031671821c1b4722c6c0eff85a9b32ca7b4e281caebf63b0
ToppCellE18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PCDH18 PEAR1

2.02e-03167182b0eb7a40491dd2432f5282f578ce569df86d21a7
ToppCelldroplet-Thymus-nan-24m-Lymphocytic-DN_to_DP_transition,_dividing_(more_DN)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP23 DNAJC18

2.04e-03168182b9db0b1e4fe54a1fe79530d15d206155a1bfac39
ToppCellAdult-Endothelial-endothelial_cell_of_artery-D122|Adult / Lineage, Cell type, age group and donor

DNAJC18 PEAR1

2.04e-031681828c3e1e45b422813bcdfa4273b1167db649a312f5
ToppCellfacs-Diaphragm-Limb_Muscle-24m|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAH6 SORCS3

2.06e-0316918212bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCelldroplet-Kidney-nan-18m-Epithelial-Pecam____kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP23 PCDH18

2.06e-0316918287116c33c5ca8cb1862e103e5607b1df4d264569
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_medulla-lymphatic_endothelial_cell_of_renal_medulla|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP23 PEAR1

2.09e-03170182dcc64b73134e89ae37990d4878813b86ce91dae9
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_medulla|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP23 PEAR1

2.09e-03170182c8c42eda44b61440c96b202e7f54650046eb95d3
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP23 PEAR1

2.09e-031701826035c92cd39c5ac54e7ec57d94888ee19f574639
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1-2_VIP_RPL41P3|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PCDH18 PEAR1

2.09e-03170182c63354930ccc9aa468407135b17984f358aabb56
ToppCellfacs-Heart-RV-18m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP23 SRRM4

2.09e-03170182d7c9a604311974ff87ece43a0f8725a234d262f7
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SORCS3 DCHS2

2.09e-03170182417b77c12a7982b1ce4b4bc57f30335d261220f5
ToppCellImmune_cells-pro-B|Immune_cells / Lineage and Cell class

TCF3 MSH5

2.14e-03172182096636f2589fa56d15942aac96641c16fd5fa78d
ToppCelldroplet-Kidney-nan-3m-Epithelial-Pecam____kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCDH18 SRRM4

2.14e-03172182073a503dc922e3e3ac3528e249b0f8b74402110b
ToppCellPND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PCDH18 PEAR1

2.14e-0317218203a0aff6b7971093a4347b5ed12546d78374c56f
ToppCellAdult-Mesenchymal-pericyte_cell-D231|Adult / Lineage, Cell type, age group and donor

PCDH18 PEAR1

2.14e-03172182858cee96c1c06160863b4adcd7023c0d678bd50f
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Mesenchymal-brain_pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCDH18 PEAR1

2.16e-031731822415b6ff49f334da570577d4e93484d024a3dbd5
ToppCellGlobus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

BEAN1 SRRM4

2.16e-031731827e3897868dd3f6e4974f593c60649a543ffc8693
ToppCellTCGA-Thryoid-Primary_Tumor-Thyroid_Papillary_Carcinoma-Tall_Cell|TCGA-Thryoid / Sample_Type by Project: Shred V9

DCHS2 BEAN1

2.16e-031731822e9dc137f3675eee07f941eb4cfcaf24a83ab0fb
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Mesenchymal-Pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCDH18 PEAR1

2.16e-031731822acd0693a2dfe04e3c1b2125ea63efe92d13150b
ToppCellfacs-Marrow-B-cells-18m-Lymphocytic-early_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCF3 MSH5

2.18e-03174182268be5e7d2a18b866770b7cdb966c3958c7e6534
ToppCellfacs-Marrow-B-cells-18m-Lymphocytic-early_pro_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCF3 MSH5

2.18e-031741824cdf2eedc28d88d18241ee390092426fdf849e79
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ARHGAP23 CLK2

2.18e-03174182207aa0118633cbe9a65839bbb1bb3ba9f8118ad2
ToppCellImmune_cells-pro-B|World / Lineage and Cell class

TCF3 MSH5

2.18e-03174182e173adbf5789dfa20f3cbc668efde5f0992ac219
ToppCellPND14-Immune-Immune_Myeloid-DC-cDC1-cDC1_prolif|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SRSF9 MSH5

2.18e-0317418209b091e24317c3f7bac043f04762a533e30793de
ToppCell343B-Lymphocytic-NK_cells-NK_cell_D3|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

DNAH6 TCF3

2.18e-03174182e5f12831187140e84b9a49e93b2376b9fefb1aec
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L5-6_FEZF2_ANKRD20A1|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SORCS3 DCHS2

2.18e-0317418299eb5e1aee136c7039e23b68a43a0fa3d775859f
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-5|TCGA-Pancreas / Sample_Type by Project: Shred V9

ARHGAP23 BEAN1

2.18e-0317418273e1ad4007d94fca25ed7c6fbe5d205d4e1b8a3b
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SORCS3 DCHS2

2.18e-031741827d4b860e05b5931f6f9d757a68f75ff35597a47a
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SORCS3 DCHS2

2.18e-03174182e4d65fe121a32ac4cdd6312e7b8f867f0852e991
ToppCellmetastatic_Lymph_Node-Endothelial_cells-Lymphatic_ECs|metastatic_Lymph_Node / Location, Cell class and cell subclass

ARHGAP23 PEAR1

2.18e-03174182d551bc29afef071adf4c9bb80345352ec33441d8
ToppCell3'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(KCNN3+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DCHS2 PCDH18

2.18e-031741829d22a554617a93701d0945de63cc3e7b24322c40
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP23 PCDH18

2.21e-0317518212f5fd83c7710fc0c77406f765d9cbd133433b8b
ToppCellP15-Mesenchymal-mesenchymal_fibroblast-tracheal_fibroblast|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

UBR5 SORCS3

2.21e-03175182085cceb1fc2c4ae2f27e85cea5702defecc2cf44
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PCDH18 PEAR1

2.21e-031751821b4cefae400bf756d09ece32d3f5c0bd4c6ad73f
ToppCellfacs-Marrow-B-cells-3m-Lymphocytic-early_pro_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCF3 MSH5

2.23e-0317618229cda51a99100ddd2928cadc92da40f001d7e1f4
ToppCell343B-Lymphocytic-NK_cells-NK_cell_D3|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

DNAH6 TCF3

2.23e-03176182bd5c85b3a4fb88ffe156599f6d224aa7664a513a
ToppCelltumor_Lymph_Node_/_Brain-Fibroblasts-Pericytes|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

DCHS2 PCDH18

2.23e-031761822015539c58aa0bb118e111ffedd63dd9fe863bb1
ToppCellControl-Neuronal_cells|Control / group, cell type (main and fine annotations)

DNAJC18 PEAR1

2.23e-03176182c29d09ecf0eb17f767d78af4b7f2e7725c967ff8
ToppCellControl-Neuronal_cells-Neuronal_cells|Control / group, cell type (main and fine annotations)

DNAJC18 PEAR1

2.23e-0317618298c07d26ba0dc0fe15ca0ea81f633d4591782bd1
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Ptprt_Pkp2|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SORCS3 BEAN1

2.23e-0317618205ec715439f2eb1696f5d8855da0dd1dd70effd0
ToppCellEndothelial-B-SSc-ILD_02|World / lung cells shred on cell class, cell subclass, sample id

ARHGAP23 PEAR1

2.23e-03176182b288116a4588a1f9db9d49af92cea118937c9201
ToppCellfacs-Marrow-B-cells-3m-Lymphocytic-early_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCF3 MSH5

2.23e-0317618201774a86d7d92f31a056b753f9844f923038003e
ToppCellmetastatic_Lymph_Node-Endothelial_cells|metastatic_Lymph_Node / Location, Cell class and cell subclass

ARHGAP23 PEAR1

2.26e-0317718271bf5d4bc67bda37a0499e5ec01af7dd5254041d
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6-Exc_L6_THEMIS_LINC00343|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DNAH6 DCHS2

2.26e-03177182921783ed0fe20294d2f384d9136924b679df01bb
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SORCS3 DCHS2

2.26e-031771824c069f0d044a96118090b85ca592a21d6b5d9399
ComputationalRNA splicing.

SRSF9 SRSF10 DUSP11

2.46e-0565103MODULE_183
DrugSAlute

UBR5 BEAN1

3.54e-064182CID000171036
Diseaseradiation-induced disorder

DCHS2 SRRM4

7.59e-0467182EFO_0009565
Diseaseirritable bowel syndrome

SORCS3 MSH5

2.86e-03131182EFO_0000555
DiseaseSclerocystic Ovaries

ARHGAP23 SRSF10

3.44e-03144182C1136382
DiseasePolycystic Ovary Syndrome

ARHGAP23 SRSF10

3.44e-03144182C0032460
Diseasemonocyte count

ARHGAP23 CLK2 TCF3 PEAR1

7.38e-031320184EFO_0005091
Diseaseobesity (implicated_via_orthology)

DCHS2 TCF3

7.49e-03215182DOID:9970 (implicated_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
RRYCGSYRRNDYSRD

CLK2

71

P49760
SYRRNDYSRDRGDAY

CLK2

76

P49760
RPSFRGNKYSRSYRY

PCDH18

846

Q9HCL0
SYSSRAYFFDNPRRY

GPR137C

341

Q8N3F9
RGSSRLDRSYSYSYS

PEAR1

881

Q5VY43
RTTTILSYDYRPSYR

DCHS2

1356

Q6V1P9
RYYNELRRRYYTTPT

DNAH6

2651

Q9C0G6
RRRWYPYNYSRLSYP

DUSP11

356

O75319
TFTAPRARPYNYYRD

DNAJC18

151

Q9H819
RYNRTSYFYPTFSES

BEAN1

11

Q3B7T3
ASAARDYGYSRPRYS

MSH5

536

O43196
RVYPERSTSYGYSRS

SRSF9

181

Q13242
TTSGRASYYVSYRRE

SORCS3

406

Q9UPU3
SRSRYSRSPYSRSRY

SRSF8

166

Q9BRL6
SRSPYSRSRYRESRY

SRSF8

171

Q9BRL6
SSSRYDDYDRYRRSR

SRSF10

106

O75494
DDYDRYRRSRSRSYE

SRSF10

111

O75494
SRSFDYNYRRSYSPR

SRSF10

131

O75494
YNYRRSYSPRNSRPT

SRSF10

136

O75494
TSQYYPSYSGSSRRR

TCF3

146

P15923
YIGYRSYSPSFQRRT

ARHGAP23

416

Q9P227
SYSRYSPSRERDPKY

SRRM4

456

A7MD48
SYFGYPSFRRSSLSR

UBR5

276

O95071