| Category | Name | IntersectionWithQuery | PValue | GenesInTerm | GenesInQuery | GenesInTermInQuery | ID |
|---|---|---|---|---|---|---|---|
| GeneOntologyMolecularFunction | actin binding | 2.78e-04 | 479 | 25 | 5 | GO:0003779 | |
| GeneOntologyMolecularFunction | cytoskeletal protein binding | 1.97e-03 | 1099 | 25 | 6 | GO:0008092 | |
| GeneOntologyMolecularFunction | protein kinase A binding | 2.38e-03 | 58 | 25 | 2 | GO:0051018 | |
| GeneOntologyBiologicalProcess | actin cytoskeleton organization | 3.06e-06 | 803 | 25 | 8 | GO:0030036 | |
| GeneOntologyBiologicalProcess | actin filament-based process | 7.83e-06 | 912 | 25 | 8 | GO:0030029 | |
| GeneOntologyBiologicalProcess | regulation of organelle organization | 1.60e-05 | 1342 | 25 | 9 | GO:0033043 | |
| GeneOntologyBiologicalProcess | actin filament organization | 2.60e-05 | 509 | 25 | 6 | GO:0007015 | |
| GeneOntologyBiologicalProcess | positive regulation of organelle organization | 5.10e-05 | 574 | 25 | 6 | GO:0010638 | |
| GeneOntologyBiologicalProcess | regulation of cytoskeleton organization | 5.36e-05 | 579 | 25 | 6 | GO:0051493 | |
| GeneOntologyBiologicalProcess | actin filament bundle assembly | 7.74e-05 | 191 | 25 | 4 | GO:0051017 | |
| GeneOntologyBiologicalProcess | actin filament bundle organization | 8.39e-05 | 195 | 25 | 4 | GO:0061572 | |
| GeneOntologyBiologicalProcess | supramolecular fiber organization | 1.04e-04 | 957 | 25 | 7 | GO:0097435 | |
| GeneOntologyBiologicalProcess | regulation of protein catabolic process | 1.12e-04 | 407 | 25 | 5 | GO:0042176 | |
| GeneOntologyBiologicalProcess | actin polymerization or depolymerization | 1.38e-04 | 222 | 25 | 4 | GO:0008154 | |
| GeneOntologyBiologicalProcess | positive regulation of protein catabolic process | 1.53e-04 | 228 | 25 | 4 | GO:0045732 | |
| GeneOntologyBiologicalProcess | regulation of supramolecular fiber organization | 1.58e-04 | 438 | 25 | 5 | GO:1902903 | |
| GeneOntologyBiologicalProcess | negative regulation of protein-containing complex disassembly | 2.35e-04 | 100 | 25 | 3 | GO:0043242 | |
| GeneOntologyBiologicalProcess | small GTPase-mediated signal transduction | 4.09e-04 | 538 | 25 | 5 | GO:0007264 | |
| GeneOntologyBiologicalProcess | regulation of actin filament organization | 4.36e-04 | 300 | 25 | 4 | GO:0110053 | |
| GeneOntologyBiologicalProcess | cytoskeleton-dependent cytokinesis | 4.75e-04 | 127 | 25 | 3 | GO:0061640 | |
| GeneOntologyBiologicalProcess | chromosome localization | 5.08e-04 | 130 | 25 | 3 | GO:0050000 | |
| GeneOntologyBiologicalProcess | regulation of small GTPase mediated signal transduction | 6.46e-04 | 333 | 25 | 4 | GO:0051056 | |
| GeneOntologyBiologicalProcess | protein polymerization | 6.53e-04 | 334 | 25 | 4 | GO:0051258 | |
| GeneOntologyBiologicalProcess | regulation of protein-containing complex disassembly | 6.85e-04 | 144 | 25 | 3 | GO:0043244 | |
| GeneOntologyBiologicalProcess | regulation of cell shape | 9.13e-04 | 159 | 25 | 3 | GO:0008360 | |
| GeneOntologyBiologicalProcess | regulation of actin cytoskeleton organization | 1.10e-03 | 384 | 25 | 4 | GO:0032956 | |
| GeneOntologyBiologicalProcess | plasma membrane bounded cell projection assembly | 1.10e-03 | 670 | 25 | 5 | GO:0120031 | |
| GeneOntologyBiologicalProcess | cell projection assembly | 1.22e-03 | 685 | 25 | 5 | GO:0030031 | |
| GeneOntologyBiologicalProcess | positive regulation of catabolic process | 1.35e-03 | 701 | 25 | 5 | GO:0009896 | |
| GeneOntologyBiologicalProcess | organelle localization | 1.37e-03 | 703 | 25 | 5 | GO:0051640 | |
| GeneOntologyBiologicalProcess | actin filament polymerization | 1.52e-03 | 190 | 25 | 3 | GO:0030041 | |
| GeneOntologyCellularComponent | actin cytoskeleton | 3.63e-06 | 576 | 25 | 7 | GO:0015629 | |
| GeneOntologyCellularComponent | lamellipodium | 1.51e-04 | 230 | 25 | 4 | GO:0030027 | |
| Domain | FH2 | 1.79e-04 | 15 | 25 | 2 | PS51444 | |
| Domain | FH2_Formin | 1.79e-04 | 15 | 25 | 2 | IPR015425 | |
| Domain | FH2 | 1.79e-04 | 15 | 25 | 2 | PF02181 | |
| Domain | FH2 | 1.79e-04 | 15 | 25 | 2 | SM00498 | |
| Domain | - | 1.49e-02 | 391 | 25 | 3 | 2.30.29.30 | |
| Domain | PH_dom-like | 1.87e-02 | 426 | 25 | 3 | IPR011993 | |
| Pathway | WP_REGULATION_OF_ACTIN_CYTOSKELETON | 9.78e-07 | 150 | 18 | 5 | M39520 | |
| Pathway | WP_REGULATION_OF_ACTIN_CYTOSKELETON | 1.04e-06 | 152 | 18 | 5 | MM15834 | |
| Pathway | KEGG_REGULATION_OF_ACTIN_CYTOSKELETON | 5.48e-06 | 213 | 18 | 5 | M18306 | |
| Pubmed | Myeloid translocation genes differentially regulate colorectal cancer programs. | 1.49e-06 | 3 | 25 | 2 | 27270437 | |
| Pubmed | 1.32e-05 | 437 | 25 | 5 | 20562859 | ||
| Pubmed | Comparative Application of BioID and TurboID for Protein-Proximity Biotinylation. | 1.64e-05 | 457 | 25 | 5 | 32344865 | |
| Pubmed | 2.67e-05 | 506 | 25 | 5 | 30890647 | ||
| Pubmed | WAVE1 is required for oligodendrocyte morphogenesis and normal CNS myelination. | 3.85e-05 | 13 | 25 | 2 | 16723544 | |
| Pubmed | N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective. | 4.22e-05 | 934 | 25 | 6 | 33916271 | |
| Pubmed | Expression of multiple formins in adult tissues and during developmental stages of mouse brain. | 4.49e-05 | 14 | 25 | 2 | 26272686 | |
| Pubmed | 5.00e-05 | 963 | 25 | 6 | 28671696 | ||
| Pubmed | MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons. | 9.53e-05 | 1082 | 25 | 6 | 38697112 | |
| Pubmed | Comparative analysis of 1196 orthologous mouse and human full-length mRNA and protein sequences. | 1.47e-04 | 25 | 25 | 2 | 8889551 | |
| Pubmed | Proteome-scale mapping of binding sites in the unstructured regions of the human proteome. | 2.37e-04 | 430 | 25 | 4 | 35044719 | |
| Pubmed | 2.74e-04 | 34 | 25 | 2 | 11101529 | ||
| Pubmed | TIF1γ inhibits lung adenocarcinoma EMT and metastasis by interacting with the TAF15/TBP complex. | 2.84e-04 | 179 | 25 | 3 | 36261009 | |
| Pubmed | 2.84e-04 | 451 | 25 | 4 | 36168627 | ||
| Pubmed | A central chaperone-like role for 14-3-3 proteins in human cells. | 3.23e-04 | 861 | 25 | 5 | 36931259 | |
| Pubmed | Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics. | 3.46e-04 | 475 | 25 | 4 | 31040226 | |
| Pubmed | PINK1 Content in Mitochondria is Regulated by ER-Associated Degradation. | 3.52e-04 | 477 | 25 | 4 | 31300519 | |
| Pubmed | 4.20e-04 | 42 | 25 | 2 | 19449303 | ||
| Pubmed | 4.30e-04 | 916 | 25 | 5 | 32203420 | ||
| Pubmed | 4.30e-04 | 1429 | 25 | 6 | 35140242 | ||
| Pubmed | 4.33e-04 | 1431 | 25 | 6 | 37142655 | ||
| Pubmed | 4.61e-04 | 44 | 25 | 2 | 27505670 | ||
| Pubmed | 4.85e-04 | 215 | 25 | 3 | 35973513 | ||
| Pubmed | 5.18e-04 | 220 | 25 | 3 | 24550385 | ||
| Pubmed | 5.60e-04 | 226 | 25 | 3 | 31452512 | ||
| Pubmed | Defining the human deubiquitinating enzyme interaction landscape. | 6.55e-04 | 1005 | 25 | 5 | 19615732 | |
| Pubmed | 6.83e-04 | 242 | 25 | 3 | 34011540 | ||
| Pubmed | Systematic Analysis of Human Protein Phosphatase Interactions and Dynamics. | 7.01e-04 | 573 | 25 | 4 | 28330616 | |
| Interaction | SH3RF1 interactions | 9.05e-06 | 108 | 25 | 4 | int:SH3RF1 | |
| Interaction | PFN1 interactions | 2.97e-05 | 509 | 25 | 6 | int:PFN1 | |
| Cytoband | Ensembl 112 genes in cytogenetic band chrXq22 | 3.96e-03 | 172 | 25 | 2 | chrXq22 | |
| Cytoband | 16p11.2 | 4.85e-03 | 191 | 25 | 2 | 16p11.2 | |
| GeneFamily | Zinc fingers MYND-type|A-kinase anchoring proteins | 2.23e-04 | 29 | 14 | 2 | 396 | |
| GeneFamily | Armadillo repeat containing|Protein phosphatase 1 regulatory subunits | 8.38e-03 | 181 | 14 | 2 | 694 | |
| GeneFamily | RNA binding motif containing | 1.15e-02 | 213 | 14 | 2 | 725 | |
| Coexpression | IVANOVA_HEMATOPOIESIS_STEM_CELL_AND_PROGENITOR | 1.33e-05 | 574 | 25 | 6 | M8215 | |
| Coexpression | IVANOVA_HEMATOPOIESIS_STEM_CELL_AND_PROGENITOR | 1.71e-05 | 600 | 25 | 6 | MM1025 | |
| Coexpression | GSE27786_BCELL_VS_NEUTROPHIL_UP | 3.67e-05 | 200 | 25 | 4 | M4813 | |
| Drug | haloperidol; Down 200; 10uM; MCF7; HT_HG-U133A | 2.18e-06 | 198 | 25 | 5 | 7003_DN | |
| Drug | Clenbuterol hydrochloride [21898-19-1]; Down 200; 12.8uM; MCF7; HT_HG-U133A | 5.73e-05 | 195 | 25 | 4 | 5631_DN | |
| Drug | Finasteride [98319-26-7]; Up 200; 10.8uM; MCF7; HT_HG-U133A | 5.85e-05 | 196 | 25 | 4 | 6062_UP | |
| Drug | Yohimbine hydrochloride [65-19-0]; Down 200; 10.2uM; PC3; HT_HG-U133A | 5.96e-05 | 197 | 25 | 4 | 7130_DN | |
| Drug | alpha-estradiol; Up 200; 0.01uM; MCF7; HT_HG-U133A | 5.96e-05 | 197 | 25 | 4 | 5207_UP | |
| Drug | Hydroflumethiazide [135-09-1]; Down 200; 12uM; PC3; HT_HG-U133A | 5.96e-05 | 197 | 25 | 4 | 1809_DN | |
| Drug | Tiaprofenic acid [33005-95-7]; Up 200; 15.4uM; HL60; HT_HG-U133A | 6.08e-05 | 198 | 25 | 4 | 2492_UP | |
| Drug | Aceclofenac [89796-99-6]; Down 200; 11.2uM; MCF7; HT_HG-U133A | 6.08e-05 | 198 | 25 | 4 | 2281_DN | |
| Drug | 2-propylpentanoic acid; Up 200; 50uM; MCF7; HT_HG-U133A | 6.20e-05 | 199 | 25 | 4 | 5219_UP | |
| Disease | Colorectal Carcinoma | 2.70e-03 | 702 | 25 | 4 | C0009402 | |
| Disease | smoking behavior, body mass index | 4.86e-03 | 123 | 25 | 2 | EFO_0004318, EFO_0004340 | |
| Disease | lung non-small cell carcinoma (is_marker_for) | 8.97e-03 | 169 | 25 | 2 | DOID:3908 (is_marker_for) |
| Peptide | Gene | Start | Entry |
|---|---|---|---|
| LPRPPVLPVPPMPPR | 241 | Q8N693 | |
| PPAAPAPPSVPMPTP | 346 | Q5H9F3 | |
| PPPPPPPMPFRAPTK | 136 | Q96JC9 | |
| PMNTVPPPPIPPIPA | 181 | Q9NTZ6 | |
| PPPPIPPIPAMPSLP | 186 | Q9NTZ6 | |
| MPSLPPMPSIPPIPV | 196 | Q9NTZ6 | |
| PMPSIPPIPVPPPVP | 201 | Q9NTZ6 | |
| PPVPPIPPVPSVPPM | 221 | Q9NTZ6 | |
| IPPVPSVPPMTPLPP | 226 | Q9NTZ6 | |
| VMSAPPPPPPPPVIP | 466 | P35241 | |
| PIPPPPPGLPPTTHM | 71 | Q9C0D6 | |
| PPMPLPVTSPLLPSP | 406 | Q8NA72 | |
| TRPTPKPTPIPTPPP | 316 | Q6UXI9 | |
| APTPPTPAPRTMPPT | 736 | Q8WUM4 | |
| TPAPRTMPPTKPQPP | 741 | Q8WUM4 | |
| TMPPTKPQPPARPPP | 746 | Q8WUM4 | |
| TQPRSTPPSMPPPPP | 71 | O75081 | |
| TPLPPPKMPPPTILS | 201 | Q8NBZ0 | |
| PPLPPHPATPPPKMV | 56 | O14556 | |
| VPPPPPPLPGMTVPT | 876 | Q9NZ56 | |
| VSMPVPPPGFSPIPP | 661 | Q9UPN6 | |
| MFPRVSPPPAPSPPK | 746 | O14654 | |
| PKTPPPMTPKTPPPV | 711 | Q9H987 | |
| PPMSPSATPPPQAPP | 936 | Q9H6K5 | |
| SPPMSPSATPPPRVP | 966 | Q9H6K5 | |
| TPNKTPQPPPPSPPM | 266 | Q9BWN1 | |
| PRMPPPLEPIPPPPS | 171 | P98174 | |
| PPITSVPRPPTMPPP | 571 | Q15459 | |
| PSPPQSPPPTPQSPM | 1471 | Q9NRY4 | |
| LPPPVTLVPPPPDTM | 41 | Q13190 | |
| MPPSRSKTPPPPPQT | 1431 | P25054 | |
| PTMPPPVLPPSLPPP | 531 | P49750 | |
| PVLPPSLPPPVMPPA | 536 | P49750 | |
| PPPVMPPSLPTSVPP | 561 | P49750 | |
| PPSLPTSVPPPGMPP | 566 | P49750 | |
| RASMTSTPPPPVPPP | 341 | Q92558 |