Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	procollagen glucosyltransferase activity	PLOD1 PLOD2	7.42e-05	3	100	2	GO:0033823
GeneOntologyMolecularFunction	procollagen-lysine 5-dioxygenase activity	PLOD1 PLOD2	7.42e-05	3	100	2	GO:0008475
GeneOntologyMolecularFunction	protein serine/threonine kinase activity	CDK8 KALRN RPS6KB1 CDK19 PRKAA2 BUB1B RPS6KA6 PRKCB IRAK3 PRKAG2	8.05e-05	446	100	10	GO:0004674
GeneOntologyMolecularFunction	SUMO ligase activity	RGPD4 RGPD1 RGPD3	1.31e-04	20	100	3	GO:0061665
GeneOntologyMolecularFunction	peptidyl-lysine 5-dioxygenase activity	PLOD1 PLOD2	1.48e-04	4	100	2	GO:0070815
GeneOntologyMolecularFunction	protein kinase activity	CDK8 KALRN RPS6KB1 CDK19 PRKAA2 BUB1B RPS6KA6 PRKCB IRAK3 ROS1 PRKAG2	2.07e-04	600	100	11	GO:0004672
GeneOntologyMolecularFunction	protein serine kinase activity	CDK8 KALRN RPS6KB1 CDK19 PRKAA2 BUB1B RPS6KA6 PRKCB	4.80e-04	363	100	8	GO:0106310
GeneOntologyMolecularFunction	GTPase activator activity	RGPD4 ARHGAP15 RGPD1 TBC1D13 RGPD3 DEPDC5 ARHGAP27	5.10e-04	279	100	7	GO:0005096
GeneOntologyMolecularFunction	ribosomal protein S6 kinase activity	RPS6KB1 RPS6KA6	5.13e-04	7	100	2	GO:0004711
GeneOntologyMolecularFunction	SUMO transferase activity	RGPD4 RGPD1 RGPD3	7.72e-04	36	100	3	GO:0019789
GeneOntologyMolecularFunction	phosphotransferase activity, alcohol group as acceptor	CDK8 KALRN RPS6KB1 CDK19 PRKAA2 BUB1B RPS6KA6 PRKCB IRAK3 ROS1 PRKAG2	8.41e-04	709	100	11	GO:0016773
GeneOntologyMolecularFunction	nucleoside-triphosphatase regulator activity	RGPD4 ARHGAP15 KALRN RGPD1 PLEKHG5 TBC1D13 RGPD3 DEPDC5 ARHGAP27	1.01e-03	507	100	9	GO:0060589
GeneOntologyMolecularFunction	GTPase regulator activity	RGPD4 ARHGAP15 KALRN RGPD1 PLEKHG5 TBC1D13 RGPD3 DEPDC5 ARHGAP27	1.01e-03	507	100	9	GO:0030695
GeneOntologyMolecularFunction	AMP-activated protein kinase activity	PRKAA2 PRKAG2	1.09e-03	10	100	2	GO:0004679
GeneOntologyMolecularFunction	small GTPase binding	RGPD4 ABCA1 GAS8 RGPD1 TBC1D13 RGPD3 DEPDC5	1.16e-03	321	100	7	GO:0031267
GeneOntologyMolecularFunction	inorganic molecular entity transmembrane transporter activity	ATP6V1C1 ATP7B GLRA3 SLC28A3 OCA2 SLC6A2 SLC41A2 SCN9A KCNMA1 ATP6V1C2 SLC25A23	1.44e-03	758	100	11	GO:0015318
GeneOntologyMolecularFunction	kinase activity	CDK8 KALRN RPS6KB1 CDK19 PRKAA2 BUB1B RPS6KA6 PRKCB IRAK3 ROS1 PRKAG2	1.53e-03	764	100	11	GO:0016301
GeneOntologyBiologicalProcess	positive regulation of glucokinase activity	RGPD4 RGPD1 RGPD3	9.37e-06	9	101	3	GO:0033133
GeneOntologyBiologicalProcess	positive regulation of hexokinase activity	RGPD4 RGPD1 RGPD3	1.33e-05	10	101	3	GO:1903301
GeneOntologyBiologicalProcess	regulation of gluconeogenesis	RGPD4 OGT RGPD1 RGPD3 GPT2	2.57e-05	71	101	5	GO:0006111
GeneOntologyBiologicalProcess	regulation of glucokinase activity	RGPD4 RGPD1 RGPD3	3.15e-05	13	101	3	GO:0033131
GeneOntologyBiologicalProcess	regulation of hexokinase activity	RGPD4 RGPD1 RGPD3	3.99e-05	14	101	3	GO:1903299
GeneOntologyBiologicalProcess	NLS-bearing protein import into nucleus	RGPD4 RGPD1 RGPD3	1.22e-04	20	101	3	GO:0006607
GeneOntologyBiologicalProcess	regulation of carbohydrate metabolic process	RGPD4 OGT RGPD1 RGPD3 PRKAA2 PRKAG2 GPT2	1.42e-04	231	101	7	GO:0006109
GeneOntologyCellularComponent	nuclear outer membrane-endoplasmic reticulum membrane network	RGPD4 ABCA1 GPAA1 DNAJC16 SYNE1 CNIH2 RGPD1 SLC28A3 OCA2 PTGIS CNIH3 RINT1 THADA MSMO1 DHCR24 RGPD3 CNIH1 PLOD1 PLOD2 SEZ6L	4.66e-06	1327	101	20	GO:0042175
GeneOntologyCellularComponent	cytoplasmic periphery of the nuclear pore complex	RGPD4 RGPD1 RGPD3	6.02e-06	8	101	3	GO:1990723
GeneOntologyCellularComponent	nuclear pore cytoplasmic filaments	RGPD4 RGPD1 RGPD3	1.28e-05	10	101	3	GO:0044614
GeneOntologyCellularComponent	annulate lamellae	RGPD4 RGPD1 RGPD3	3.83e-05	14	101	3	GO:0005642
GeneOntologyCellularComponent	perinuclear region of cytoplasm	RGPD4 ABCA1 ATP7B KRT18 KALRN SYNE1 RPS6KB1 CDK19 RGPD1 PLEKHG5 RGPD3 BUB1B KCNMA1 DEPDC5 ROS1	4.13e-05	934	101	15	GO:0048471
GeneOntologyCellularComponent	nuclear pore nuclear basket	RGPD4 RGPD1 RGPD3	8.47e-05	18	101	3	GO:0044615
GeneOntologyCellularComponent	nuclear inclusion body	RGPD4 RGPD1 RGPD3	1.18e-04	20	101	3	GO:0042405
GeneOntologyCellularComponent	SUMO ligase complex	RGPD4 RGPD1 RGPD3	1.37e-04	21	101	3	GO:0106068
GeneOntologyCellularComponent	CKM complex	CDK8 CDK19	2.29e-04	5	101	2	GO:1990508
GeneOntologyCellularComponent	endoplasmic reticulum membrane	ABCA1 GPAA1 DNAJC16 CNIH2 SLC28A3 OCA2 PTGIS CNIH3 RINT1 THADA MSMO1 DHCR24 CNIH1 PLOD1 PLOD2 SEZ6L	4.57e-04	1293	101	16	GO:0005789
GeneOntologyCellularComponent	endoplasmic reticulum subcompartment	ABCA1 GPAA1 DNAJC16 CNIH2 SLC28A3 OCA2 PTGIS CNIH3 RINT1 THADA MSMO1 DHCR24 CNIH1 PLOD1 PLOD2 SEZ6L	4.81e-04	1299	101	16	GO:0098827
GeneOntologyCellularComponent	nucleotide-activated protein kinase complex	PRKAA2 PRKAG2	1.24e-03	11	101	2	GO:0031588
GeneOntologyCellularComponent	vacuolar proton-transporting V-type ATPase, V1 domain	ATP6V1C1 ATP6V1C2	1.48e-03	12	101	2	GO:0000221
GeneOntologyCellularComponent	proton-transporting V-type ATPase, V1 domain	ATP6V1C1 ATP6V1C2	1.48e-03	12	101	2	GO:0033180
MousePheno	increased hepatocellular carcinoma incidence	RGPD4 KRT18 RGPD1 RINT1 RGPD3 BUB1B	3.06e-06	70	81	6	MP:0003331
MousePheno	abnormal impulse conducting system morphology	XIRP2 PRKAG2 TBX5	2.18e-05	10	81	3	MP:0004123
MousePheno	decreased tumor latency	RGPD4 RGPD1 RGPD3 BUB1B	2.56e-05	30	81	4	MP:0010308
MousePheno	abnormal tumor latency	RGPD4 RGPD1 RGPD3 BUB1B	4.25e-05	34	81	4	MP:0010307
MousePheno	increased hepatobiliary system tumor incidence	RGPD4 KRT18 RGPD1 RINT1 RGPD3 BUB1B	4.38e-05	111	81	6	MP:0010297
MousePheno	increased liver tumor incidence	RGPD4 KRT18 RGPD1 RINT1 RGPD3 BUB1B	4.38e-05	111	81	6	MP:0008019
MousePheno	increased lung carcinoma incidence	RGPD4 RGPD1 RINT1 RGPD3 BUB1B	8.74e-05	78	81	5	MP:0008714
MousePheno	abnormal atrioventricular bundle morphology	XIRP2 TBX5	9.91e-05	3	81	2	MP:0004117
MousePheno	elevated level of mitotic sister chromatid exchange	RGPD4 RGPD1 RGPD3	9.94e-05	16	81	3	MP:0003701
Domain	Cornichon_conserved	CNIH2 CNIH3 CNIH1	1.49e-07	3	100	3	IPR033466
Domain	CORNICHON	CNIH2 CNIH3 CNIH1	1.49e-07	3	100	3	PS01340
Domain	Cornichon	CNIH2 CNIH3 CNIH1	5.93e-07	4	100	3	PF03311
Domain	Cornichon	CNIH2 CNIH3 CNIH1	5.93e-07	4	100	3	IPR003377
Domain	Cornichon	CNIH2 CNIH3 CNIH1	5.93e-07	4	100	3	SM01398
Domain	GCC2_Rab_bind	RGPD4 RGPD1 RGPD3	5.13e-06	7	100	3	IPR032023
Domain	Rab_bind	RGPD4 RGPD1 RGPD3	5.13e-06	7	100	3	PF16704
Domain	-	RGPD4 RGPD1 RGPD3	1.74e-05	10	100	3	1.10.220.60
Domain	Grip	RGPD4 RGPD1 RGPD3	2.38e-05	11	100	3	SM00755
Domain	GRIP	RGPD4 RGPD1 RGPD3	2.38e-05	11	100	3	PF01465
Domain	ATPase_V1-cplx_csu	ATP6V1C1 ATP6V1C2	2.84e-05	2	100	2	IPR004907
Domain	V-ATPase_C	ATP6V1C1 ATP6V1C2	2.84e-05	2	100	2	PF03223
Domain	Ran_BP1	RGPD4 RGPD1 RGPD3	3.16e-05	12	100	3	PF00638
Domain	GRIP_dom	RGPD4 RGPD1 RGPD3	3.16e-05	12	100	3	IPR000237
Domain	GRIP	RGPD4 RGPD1 RGPD3	3.16e-05	12	100	3	PS50913
Domain	RANBD1	RGPD4 RGPD1 RGPD3	3.16e-05	12	100	3	PS50196
Domain	RanBD	RGPD4 RGPD1 RGPD3	4.10e-05	13	100	3	SM00160
Domain	Ran_bind_dom	RGPD4 RGPD1 RGPD3	4.10e-05	13	100	3	IPR000156
Domain	LYS_HYDROXYLASE	PLOD1 PLOD2	8.48e-05	3	100	2	PS01325
Domain	Procol_lys_dOase	PLOD1 PLOD2	8.48e-05	3	100	2	IPR001006
Domain	Ser/Thr_kinase_AS	CDK8 KALRN RPS6KB1 CDK19 PRKAA2 BUB1B RPS6KA6 PRKCB IRAK3	1.27e-04	357	100	9	IPR008271
Domain	PROTEIN_KINASE_ST	CDK8 KALRN RPS6KB1 CDK19 PRKAA2 BUB1B RPS6KA6 PRKCB IRAK3	1.41e-04	362	100	9	PS00108
Domain	SSU_processome_Utp12	WDR43 PWP2	1.69e-04	4	100	2	IPR007148
Domain	Utp12	WDR43 PWP2	1.69e-04	4	100	2	PF04003
Domain	Rho_GTPase_act	ARHGAP15 ARHGAP27	1.69e-04	4	100	2	IPR015767
Domain	PROTEIN_KINASE_ATP	CDK8 KALRN RPS6KB1 CDK19 PRKAA2 BUB1B RPS6KA6 PRKCB IRAK3 ROS1	1.75e-04	459	100	10	PS00107
Domain	Quinoprotein_ADH-like_supfam	EML6 PWP2 ARHGAP27 WDR72	1.85e-04	53	100	4	IPR011047
Domain	Pkinase	CDK8 KALRN RPS6KB1 CDK19 PRKAA2 BUB1B RPS6KA6 PRKCB IRAK3	2.07e-04	381	100	9	PF00069
Domain	Prot_kinase_dom	CDK8 KALRN RPS6KB1 CDK19 PRKAA2 BUB1B RPS6KA6 PRKCB IRAK3 ROS1	2.91e-04	489	100	10	IPR000719
Domain	PROTEIN_KINASE_DOM	CDK8 KALRN RPS6KB1 CDK19 PRKAA2 BUB1B RPS6KA6 PRKCB IRAK3 ROS1	3.10e-04	493	100	10	PS50011
Domain	Kinase-like_dom	CDK8 KALRN RPS6KB1 CDK19 PRKAA2 BUB1B RPS6KA6 PRKCB IRAK3 ROS1	6.51e-04	542	100	10	IPR011009
Domain	Protein_kinase_ATP_BS	CDK8 KALRN RPS6KB1 CDK19 PRKAA2 RPS6KA6 PRKCB ROS1	9.80e-04	379	100	8	IPR017441
Domain	Pkinase_C	RPS6KB1 RPS6KA6 PRKCB	1.01e-03	37	100	3	IPR017892
Domain	Pkinase_C	RPS6KB1 RPS6KA6 PRKCB	1.47e-03	42	100	3	PF00433
Domain	S_TKc	CDK8 KALRN RPS6KB1 CDK19 PRKAA2 RPS6KA6 PRKCB	3.17e-03	359	100	7	SM00220
Domain	P4Hc	PLOD1 PLOD2	3.24e-03	16	100	2	SM00702
Domain	Pro_4_hyd_alph	PLOD1 PLOD2	3.24e-03	16	100	2	IPR006620
Domain	AGC-kinase_C	RPS6KB1 RPS6KA6 PRKCB	3.36e-03	56	100	3	IPR000961
Domain	AGC_KINASE_CTER	RPS6KB1 RPS6KA6 PRKCB	3.36e-03	56	100	3	PS51285
Domain	S_TK_X	RPS6KB1 RPS6KA6 PRKCB	3.36e-03	56	100	3	SM00133
Domain	2OG-FeII_Oxy	PLOD1 PLOD2	4.57e-03	19	100	2	PF03171
Domain	-	RGPD4 ARHGAP15 KALRN RGPD1 PLEKHG5 RGPD3 ARHGAP27	5.05e-03	391	100	7	2.30.29.30
Domain	TPR	RGPD4 OGT RGPD1 RGPD3	5.11e-03	129	100	4	SM00028
Domain	FE2OG_OXY	PLOD1 PLOD2	5.58e-03	21	100	2	PS51471
Domain	TPR_repeat	RGPD4 OGT RGPD1 RGPD3	5.69e-03	133	100	4	IPR019734
Pubmed	Upregulation of cornichon transcripts in the dorsolateral prefrontal cortex in schizophrenia.	CNIH2 CNIH3 CNIH1	2.38e-08	3	101	3	23103966
Pubmed	Cross-talk between two essential nutrient-sensitive enzymes: O-GlcNAc transferase (OGT) and AMP-activated protein kinase (AMPK).	OGT PRKAA2 PRKAG2	4.72e-07	6	101	3	24563466
Pubmed	Interconversion of red opsin isoforms by the cyclophilin-related chaperone protein Ran-binding protein 2.	RGPD4 RGPD1 RGPD3	8.25e-07	7	101	3	9037092
Pubmed	Complex genomic rearrangements lead to novel primate gene function.	RGPD4 RGPD1 RGPD3	8.25e-07	7	101	3	15710750
Pubmed	Genomic organization, expression, and localization of murine Ran-binding protein 2 (RanBP2) gene.	RGPD4 RGPD1 RGPD3	8.25e-07	7	101	3	11353387
Pubmed	Microglial activation in an amyotrophic lateral sclerosis-like model caused by Ranbp2 loss and nucleocytoplasmic transport impairment in retinal ganglion neurons.	RGPD4 RGPD1 RGPD3	8.25e-07	7	101	3	30944974
Pubmed	Nucleoporin Nup358 drives the differentiation of myeloid-biased multipotent progenitors by modulating HDAC3 nuclear translocation.	RGPD4 RGPD1 RGPD3	8.25e-07	7	101	3	38838144
Pubmed	Retina-specifically expressed novel subtypes of bovine cyclophilin.	RGPD4 RGPD1 RGPD3	8.25e-07	7	101	3	7559465
Pubmed	Mst1, RanBP2 and eIF4G are new markers for in vivo PI3K activation in murine and human prostate.	RGPD4 RGPD1 RGPD3	8.25e-07	7	101	3	17372272
Pubmed	Proteostatic Remodeling of Small Heat Shock Chaperones─Crystallins by Ran-Binding Protein 2─and the Peptidyl-Prolyl cis-trans Isomerase and Chaperone Activities of Its Cyclophilin Domain.	RGPD4 RGPD1 RGPD3	8.25e-07	7	101	3	38657106
Pubmed	Nup358, a nucleoporin, functions as a key determinant of the nuclear pore complex structure remodeling during skeletal myogenesis.	RGPD4 RGPD1 RGPD3	8.25e-07	7	101	3	21205196
Pubmed	Haploinsufficiency of RanBP2 is neuroprotective against light-elicited and age-dependent degeneration of photoreceptor neurons.	RGPD4 RGPD1 RGPD3	8.25e-07	7	101	3	18949001
Pubmed	Selective impairment of a subset of Ran-GTP-binding domains of ran-binding protein 2 (Ranbp2) suffices to recapitulate the degeneration of the retinal pigment epithelium (RPE) triggered by Ranbp2 ablation.	RGPD4 RGPD1 RGPD3	8.25e-07	7	101	3	25187515
Pubmed	Localization of the Ran-GTP binding protein RanBP2 at the cytoplasmic side of the nuclear pore complex.	RGPD4 RGPD1 RGPD3	8.25e-07	7	101	3	8603673
Pubmed	Uncoupling phototoxicity-elicited neural dysmorphology and death by insidious function and selective impairment of Ran-binding protein 2 (Ranbp2).	RGPD4 RGPD1 RGPD3	8.25e-07	7	101	3	26632511
Pubmed	Differential loss of prolyl isomerase or chaperone activity of Ran-binding protein 2 (Ranbp2) unveils distinct physiological roles of its cyclophilin domain in proteostasis.	RGPD4 RGPD1 RGPD3	8.25e-07	7	101	3	24403063
Pubmed	Distinct and atypical intrinsic and extrinsic cell death pathways between photoreceptor cell types upon specific ablation of Ranbp2 in cone photoreceptors.	RGPD4 RGPD1 RGPD3	8.25e-07	7	101	3	23818861
Pubmed	Kinesin-1 and mitochondrial motility control by discrimination of structurally equivalent but distinct subdomains in Ran-GTP-binding domains of Ran-binding protein 2.	RGPD4 RGPD1 RGPD3	8.25e-07	7	101	3	23536549
Pubmed	Identification of RanBP2- and kinesin-mediated transport pathways with restricted neuronal and subcellular localization.	RGPD4 RGPD1 RGPD3	8.25e-07	7	101	3	12191015
Pubmed	Ranbp2 haploinsufficiency mediates distinct cellular and biochemical phenotypes in brain and retinal dopaminergic and glia cells elicited by the Parkinsonian neurotoxin, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).	RGPD4 RGPD1 RGPD3	8.25e-07	7	101	3	22821000
Pubmed	Neuroprotection resulting from insufficiency of RANBP2 is associated with the modulation of protein and lipid homeostasis of functionally diverse but linked pathways in response to oxidative stress.	RGPD4 RGPD1 RGPD3	8.25e-07	7	101	3	20682751
Pubmed	The nucleoporin RanBP2 tethers the cAMP effector Epac1 and inhibits its catalytic activity.	RGPD4 RGPD1 RGPD3	1.32e-06	8	101	3	21670213
Pubmed	Critical role of RanBP2-mediated SUMOylation of Small Heterodimer Partner in maintaining bile acid homeostasis.	RGPD4 RGPD1 RGPD3	1.32e-06	8	101	3	27412403
Pubmed	Mice lacking Ran binding protein 1 are viable and show male infertility.	RGPD4 RGPD1 RGPD3	1.32e-06	8	101	3	21310149
Pubmed	The distribution of phosphorylated SR proteins and alternative splicing are regulated by RANBP2.	RGPD4 RGPD1 RGPD3	1.32e-06	8	101	3	22262462
Pubmed	Zap70 and downstream RanBP2 are required for the exact timing of the meiotic cell cycle in oocytes.	RGPD4 RGPD1 RGPD3	1.32e-06	8	101	3	28745977
Pubmed	Resolution of sister centromeres requires RanBP2-mediated SUMOylation of topoisomerase IIalpha.	RGPD4 RGPD1 RGPD3	1.97e-06	9	101	3	18394993
Pubmed	Loss of Ranbp2 in motoneurons causes disruption of nucleocytoplasmic and chemokine signaling, proteostasis of hnRNPH3 and Mmp28, and development of amyotrophic lateral sclerosis-like syndromes.	RGPD4 RGPD1 RGPD3	1.97e-06	9	101	3	28100513
Pubmed	Association of the kinesin-binding domain of RanBP2 to KIF5B and KIF5C determines mitochondria localization and function.	RGPD4 RGPD1 RGPD3	1.97e-06	9	101	3	17887960
Pubmed	The docking of kinesins, KIF5B and KIF5C, to Ran-binding protein 2 (RanBP2) is mediated via a novel RanBP2 domain.	RGPD4 RGPD1 RGPD3	1.97e-06	9	101	3	11553612
Pubmed	The zinc finger cluster domain of RanBP2 is a specific docking site for the nuclear export factor, exportin-1.	RGPD4 RGPD1 RGPD3	1.97e-06	9	101	3	10601307
Pubmed	The cyclophilin-like domain mediates the association of Ran-binding protein 2 with subunits of the 19 S regulatory complex of the proteasome.	RGPD4 RGPD1 RGPD3	1.97e-06	9	101	3	9733766
Pubmed	Impairments in age-dependent ubiquitin proteostasis and structural integrity of selective neurons by uncoupling Ran GTPase from the Ran-binding domain 3 of Ranbp2 and identification of novel mitochondrial isoforms of ubiquitin-conjugating enzyme E2I (ubc9) and Ranbp2.	RGPD4 RGPD1 RGPD3	1.97e-06	9	101	3	28877029
Pubmed	The RanBP2/RanGAP1*SUMO1/Ubc9 SUMO E3 ligase is a disassembly machine for Crm1-dependent nuclear export complexes.	RGPD4 RGPD1 RGPD3	2.81e-06	10	101	3	27160050
Pubmed	Parkin ubiquitinates and promotes the degradation of RanBP2.	RGPD4 RGPD1 RGPD3	2.81e-06	10	101	3	16332688
Pubmed	Cyclophilin-related protein RanBP2 acts as chaperone for red/green opsin.	RGPD4 RGPD1 RGPD3	2.81e-06	10	101	3	8857542
Pubmed	Ran-dependent docking of importin-beta to RanBP2/Nup358 filaments is essential for protein import and cell viability.	RGPD4 RGPD1 RGPD3	2.81e-06	10	101	3	21859863
Pubmed	RanBP2 modulates Cox11 and hexokinase I activities and haploinsufficiency of RanBP2 causes deficits in glucose metabolism.	RGPD4 RGPD1 RGPD3	3.86e-06	11	101	3	17069463
Pubmed	An Rtn4/Nogo-A-interacting micropeptide modulates synaptic plasticity with age.	RGPD4 RGPD1 RGPD3	3.86e-06	11	101	3	35771867
Pubmed	T-cell receptor (TCR) signaling promotes the assembly of RanBP2/RanGAP1-SUMO1/Ubc9 nuclear pore subcomplex via PKC-θ-mediated phosphorylation of RanGAP1.	RGPD4 RGPD1 RGPD3	3.86e-06	11	101	3	34110283
Pubmed	Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.	KALRN SYNE1 DNAH7 PTGIS XIRP2 SCN9A RPS6KA6	5.58e-06	233	101	7	37704626
Pubmed	Ankyrin-G induces nucleoporin Nup358 to associate with the axon initial segment of neurons.	RGPD4 RGPD1 RGPD3	6.66e-06	13	101	3	31427429
Pubmed	Inhibition of Cyclin-Dependent Kinase 8/Cyclin-Dependent Kinase 19 Suppresses Its Pro-Oncogenic Effects in Prostate Cancer.	CDK8 CDK19	8.35e-06	2	101	2	35181333
Pubmed	Regulatory functions of the Mediator kinases CDK8 and CDK19.	CDK8 CDK19	8.35e-06	2	101	2	30585107
Pubmed	Multi-cancer V-ATPase molecular signatures: A distinctive balance of subunit C isoforms in esophageal carcinoma.	ATP6V1C1 ATP6V1C2	8.35e-06	2	101	2	31901859
Pubmed	HIV Transcription Is Independent of Mediator Kinases.	CDK8 CDK19	8.35e-06	2	101	2	31044597
Pubmed	AMPA receptor modulation by cornichon-2 dictated by transmembrane AMPA receptor regulatory protein isoform.	CNIH2 CNIH1	8.35e-06	2	101	2	22211840
Pubmed	The context of HLA-DR/CD18 complex in the plasma membrane governs HLA-DR-derived signals in activated monocytes.	ITGB2 PRKCB	8.35e-06	2	101	2	17719638
Pubmed	Cyclin-Dependent Kinases 8 and 19 Regulate Host Cell Metabolism during Dengue Virus Serotype 2 Infection.	CDK8 CDK19	8.35e-06	2	101	2	32560467
Pubmed	Increased alpha2 subunit-associated AMPK activity and PRKAG2 cardiomyopathy.	PRKAA2 PRKAG2	8.35e-06	2	101	2	16275868
Pubmed	[Mechanisms of transcriptional regulation upon protein phosphorylation by mediator complexes].	CDK8 CDK19	8.35e-06	2	101	2	20408451
Pubmed	Mediator kinase inhibition further activates super-enhancer-associated genes in AML.	CDK8 CDK19	8.35e-06	2	101	2	26416749
Pubmed	CDK8/19 Mediator kinases potentiate induction of transcription by NFκB.	CDK8 CDK19	8.35e-06	2	101	2	28855340
Pubmed	Pan-Cancer Analysis of the Mediator Complex Transcriptome Identifies CDK19 and CDK8 as Therapeutic Targets in Advanced Prostate Cancer.	CDK8 CDK19	8.35e-06	2	101	2	27678455
Pubmed	CDK8 and CDK19 regulate intestinal differentiation and homeostasis via the chromatin remodeling complex SWI/SNF.	CDK8 CDK19	8.35e-06	2	101	2	36006697
Pubmed	CDK8 and CDK19: positive regulators of signal-induced transcription and negative regulators of Mediator complex proteins.	CDK8 CDK19	8.35e-06	2	101	2	37378433
Pubmed	p70S6 kinase phosphorylates AMPK on serine 491 to mediate leptin's effect on food intake.	RPS6KB1 PRKAA2	8.35e-06	2	101	2	22727014
Pubmed	The mouse cornichon gene family.	CNIH2 CNIH1	8.35e-06	2	101	2	10022955
Pubmed	Identification of target genes for the CDK subunits of the Mediator complex.	CDK8 CDK19	8.35e-06	2	101	2	22117896
Pubmed	Limited expression of nuclear pore membrane glycoprotein 210 in cell lines and tissues suggests cell-type specific nuclear pores in metazoans.	RGPD4 RGPD1 RGPD3	1.05e-05	15	101	3	14697343
Pubmed	Mediator complex cooperatively regulates transcription of retinoic acid target genes with Polycomb Repressive Complex 2 during neuronal differentiation.	CDK8 CDK19	2.50e-05	3	101	2	26002960
Pubmed	Characterization of cDNAs for mouse lysyl hydroxylase 1, 2 and 3, their phylogenetic analysis and tissue-specific expression in the mouse.	PLOD1 PLOD2	2.50e-05	3	101	2	10429951
Pubmed	Identification of amino acids important for the catalytic activity of the collagen glucosyltransferase associated with the multifunctional lysyl hydroxylase 3 (LH3).	PLOD1 PLOD2	2.50e-05	3	101	2	11896059
Pubmed	Characterization of three fragments that constitute the monomers of the human lysyl hydroxylase isoenzymes 1-3. The 30-kDa N-terminal fragment is not required for lysyl hydroxylase activity.	PLOD1 PLOD2	2.50e-05	3	101	2	11956192
Pubmed	Lysyl hydroxylase 3 is a multifunctional protein possessing collagen glucosyltransferase activity.	PLOD1 PLOD2	2.50e-05	3	101	2	10934207
Pubmed	Primary structure, tissue distribution, and chromosomal localization of a novel isoform of lysyl hydroxylase (lysyl hydroxylase 3).	PLOD1 PLOD2	2.50e-05	3	101	2	9582318
Pubmed	The lysyl hydroxylase isoforms are widely expressed during mouse embryogenesis, but obtain tissue- and cell-specific patterns in the adult.	PLOD1 PLOD2	2.50e-05	3	101	2	16996725
Pubmed	A single C-terminal peptide segment mediates both membrane association and localization of lysyl hydroxylase in the endoplasmic reticulum.	PLOD1 PLOD2	2.50e-05	3	101	2	10748089
Pubmed	The genes encoding mouse lysyl hydroxylase isoforms map to chromosomes 4,5, and 9.	PLOD1 PLOD2	2.50e-05	3	101	2	11130984
Pubmed	Mediator cyclin-dependent kinases upregulate transcription of inflammatory genes in cooperation with NF-κB and C/EBPβ on stimulation of Toll-like receptor 9.	CDK8 CDK19	2.50e-05	3	101	2	28151579
Pubmed	Procollagen-lysine, 2-oxoglutarate 5-dioxygenases 1, 2, and 3 are potential prognostic indicators in patients with clear cell renal cell carcinoma.	PLOD1 PLOD2	2.50e-05	3	101	2	31446433
Pubmed	PITX2 regulates procollagen lysyl hydroxylase (PLOD) gene expression: implications for the pathology of Rieger syndrome.	PLOD1 PLOD2	2.50e-05	3	101	2	11157981
Pubmed	OGT suppresses S6K1-mediated macrophage inflammation and metabolic disturbance.	OGT RPS6KB1	2.50e-05	3	101	2	32601203
Pubmed	Systematic analysis of human protein complexes identifies chromosome segregation proteins.	RGPD4 OGT SYNE1 RGPD1 WDR43 FAM83B RINT1 RGPD3 BUB1B COPS4 PLOD1 PLOD2 STAG2	3.05e-05	1155	101	13	20360068
Pubmed	Terminal differentiation of cortical neurons rapidly remodels RanGAP-mediated nuclear transport system.	RGPD4 RGPD1 RGPD3	3.52e-05	22	101	3	27717094
Pubmed	Interaction of Sox2 with RNA binding proteins in mouse embryonic stem cells.	RGPD4 OGT RGPD1 RGPD3 PRKAG2	4.81e-05	135	101	5	31077711
Pubmed	AMP kinase and malonyl-CoA: targets for therapy of the metabolic syndrome.	PRKAA2 PRKAG2	4.99e-05	4	101	2	15060529
Pubmed	O-GlcNAcylation of Raptor transduces glucose signals to mTORC1.	OGT PRKAA2	4.99e-05	4	101	2	37541260
Pubmed	Oncogenic exon 2 mutations in Mediator subunit MED12 disrupt allosteric activation of cyclin C-CDK8/19.	CDK8 CDK19	4.99e-05	4	101	2	29440396
Pubmed	Glycosylation catalyzed by lysyl hydroxylase 3 is essential for basement membranes.	PLOD1 PLOD2	4.99e-05	4	101	2	16467571
Pubmed	Cdk8 is required for establishment of H3K27me3 and gene repression by Xist and mouse development.	CDK8 CDK19	4.99e-05	4	101	2	32439758
Pubmed	STIM1 calcium sensor is required for activation of the phagocyte oxidase during inflammation and host defense.	ITGB2 PRKCB	4.99e-05	4	101	2	24493668
Pubmed	T-independent type II immune responses generate memory B cells.	AICDA PRKCB	4.99e-05	4	101	2	16476769
Pubmed	Emerging links between initiation of translation and human diseases.	ABCA1 OGT	4.99e-05	4	101	2	12226704
Pubmed	Genetic factors for ischemic and hemorrhagic stroke in Japanese individuals.	ABCA1 ROS1	4.99e-05	4	101	2	18566305
Pubmed	PLODs are overexpressed in ovarian cancer and are associated with gap junctions via connexin 43.	PLOD1 PLOD2	4.99e-05	4	101	2	33483598
Pubmed	AMPK/mTOR/p70S6K axis prevents apoptosis of Porphyromonas gingivalis-infected gingival epithelial cells via BadSer136 phosphorylation.	RPS6KB1 PRKAA2	4.99e-05	4	101	2	37014579
Pubmed	Endothelial cells regulate neural crest and second heart field morphogenesis.	PLOD1 PLOD2 TBX5	5.89e-05	26	101	3	24996922
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	RGPD4 KRT18 SYNE1 EML6 RGPD1 RINT1 CEBPZ SNX25 RGPD3 PWP2 SCN9A IRAK3 NGLY1 STAG2	7.33e-05	1442	101	14	35575683
Pubmed	Deficiency of insulin-like growth factor 1 reduces sensitivity to aging-associated cardiomyocyte dysfunction.	KL PRKAA2	8.30e-05	5	101	2	18729805
Pubmed	Reassignment of the H-ras-1 gene to the Hbb-terminus region of mouse chromosome 7.	OCA2 PRKCB	8.30e-05	5	101	2	8499656
Pubmed	CDK8 and CDK19 act redundantly to control the CFTR pathway in the intestinal epithelium.	CDK8 CDK19	8.30e-05	5	101	2	36545778
Pubmed	Association of a polymorphism of the apolipoprotein E gene with chronic kidney disease in Japanese individuals with metabolic syndrome.	ABCA1 ITGB2 PTGIS ROS1	8.52e-05	79	101	4	19056482
Pubmed	AMPK Dilates Resistance Arteries via Activation of SERCA and BKCa Channels in Smooth Muscle.	PRKAA2 KCNMA1	1.24e-04	6	101	2	26034200
Pubmed	Functional comparison of the effects of TARPs and cornichons on AMPA receptor trafficking and gating.	CNIH2 CNIH3	1.24e-04	6	101	2	20805473
Pubmed	AMP-activated protein kinase isoenzyme family: subunit structure and chromosomal location.	PRKAA2 PRKAG2	1.24e-04	6	101	2	9224708
Pubmed	Threonine phosphorylation sites in the beta 2 and beta 7 leukocyte integrin polypeptides.	ITGB2 PRKCB	1.24e-04	6	101	2	12682249
Pubmed	Association of polymorphisms of ABCA1 and ROS1 with hypertension in Japanese individuals.	ABCA1 ROS1	1.24e-04	6	101	2	18097620
Pubmed	Stimulation of the AMP-activated protein kinase leads to activation of eukaryotic elongation factor 2 kinase and to its phosphorylation at a novel site, serine 398.	RPS6KB1 PRKAA2	1.24e-04	6	101	2	14709557
Pubmed	Cornichon proteins determine the subunit composition of synaptic AMPA receptors.	CNIH2 CNIH3	1.24e-04	6	101	2	23522044
GeneFamily	Cyclins\|Mediator complex	CDK8 CDK19 MED12L	2.79e-04	33	70	3	1061
GeneFamily	Tetratricopeptide repeat domain containing\|Bardet-Biedl syndrome associated\|BBSome	RGPD4 OGT RGPD1 RGPD3	1.03e-03	115	70	4	769
ToppCell	COVID-19-lung-Macrophage_CD163hi_MERTKhi\|lung / Disease (COVID-19 only), tissue and cell type	RNF144B ABCA1 ARHGAP15 STAB1 KCNMA1 PRKCB IRAK3 PRKAG2	1.54e-08	195	101	8	148fff8c3c9ba45ec36e98dff1be57e3f8294506
ToppCell	Adult-Immune-monocyte-D122\|Adult / Lineage, Cell type, age group and donor	PLB1 ARHGAP15 ITGB2 STAB1 KCNMA1 PRKCB IRAK3 PRKAG2	1.61e-08	196	101	8	16b0acb6157534938ca83d4e909471e33a7d3c52
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TRHDE RNF144B SYNE1 EML6 OCA2 SMOC2 PTPRT	1.63e-07	177	101	7	da8802a6351d3e510822f82e2fde8a4314a2216e
ToppCell	Control-Myeloid-Dendritic_cells\|Control / group, cell type (main and fine annotations)	RNF144B ARHGAP15 STAB1 KCNMA1 MED12L PRKCB IRAK3	1.83e-07	180	101	7	25ad95c3c30e3b82abe93bd77ba003f5c2241f7c
ToppCell	RV-08._Macrophage\|RV / Chamber and Cluster_Paper	ARHGAP15 STAB1 BUB1B SCN9A KCNMA1 PRKCB IRAK3	2.93e-07	193	101	7	12bf98a280f87e4d8f0c6887dfc855da72e47ac1
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PLB1 ABCA1 ARHGAP15 PLEKHG5 STAB1 KCNMA1 PRKCB	3.04e-07	194	101	7	1dce6d4b6ac41f80677e3e4c335a4f383bd76f85
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Macrophage_Dendritic\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	RNF144B ABCA1 PLEKHG5 STAB1 SLC41A2 KCNMA1 IRAK3	3.14e-07	195	101	7	247803cf58c6d9c561a52aa34e581188ddad197e
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ABCA1 ARHGAP15 PLEKHG5 STAB1 KCNMA1 PRKCB IRAK3	3.14e-07	195	101	7	42bfdff88da1d07828c0ad65d412fb1752f0cee4
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	RNF144B PLB1 ARHGAP15 STAB1 KCNMA1 PRKCB IRAK3	3.25e-07	196	101	7	cbc727b55b6433a701b1a331028a49960fcee6ee
ToppCell	COVID-19-lung-Macrophage_CD163hi_MERTKhi\|COVID-19 / Disease (COVID-19 only), tissue and cell type	RNF144B ABCA1 ARHGAP15 STAB1 KCNMA1 PRKCB IRAK3	3.25e-07	196	101	7	7026c1fc33425e5476063d17c79e4b79356a9e01
ToppCell	mLN-B_cell-B_cell_cycling\|mLN / Region, Cell class and subclass	RNF144B AICDA CNIH3 TCL1A BUB1B KCNMA1 MED12L	3.37e-07	197	101	7	806dddcca85c82bd642008d930c8db16b613d88e
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	RNF144B PLB1 ARHGAP15 STAB1 KCNMA1 PRKCB IRAK3	3.37e-07	197	101	7	6ca6e17b7cc5f7ea8d4b6ca1ff670969bee65a45
ToppCell	COVID-19-kidney-Macrophages\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ABCA1 ARHGAP15 ITGB2 KCNMA1 PRKCB IRAK3 PRKAG2	3.37e-07	197	101	7	3912301018d0863144dcfac8d1fa8adc081748d7
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PLB1 ARHGAP15 ITGB2 PLEKHG5 STAB1 KCNMA1 PRKCB	3.37e-07	197	101	7	d95565652ca318a2298d6918d54ba6367e9560f4
ToppCell	COVID-19-lung-Macrophage_LDB2hi_OSMRhi_YAP1hi\|lung / Disease (COVID-19 only), tissue and cell type	RNF144B ARHGAP15 STAB1 KCNMA1 PRKCB IRAK3 PRKAG2	3.37e-07	197	101	7	3896729740d151f0eb845f1961c7b969bfbdd28d
ToppCell	mLN-(2)_B_cell-(24)_B_cell_cycling\|mLN / shred on region, Cell_type, and subtype	RNF144B AICDA CNIH3 TCL1A BUB1B KCNMA1 MED12L	3.37e-07	197	101	7	70fff2d6723f259e18e7a21d22dc46d71f0759ce
ToppCell	AT2_cells\|World / lung cells shred on cell class, cell subclass, sample id	RAB25 KRT18 SYNE1 MSMO1 SNX25 TMEM245 DHCR24	3.49e-07	198	101	7	92c569c3b8a9fca2d4682cbf77ee8149bcc0a80a
ToppCell	Biopsy_Other_PF-Epithelial-AT2\|Biopsy_Other_PF / Sample group, Lineage and Cell type	RAB25 KRT18 SYNE1 MSMO1 SNX25 DHCR24 ROS1	3.61e-07	199	101	7	9a65acfe9bf500db72142469cf17bf0973540001
ToppCell	Epithelial_cells\|World / lung cells shred on cell class, cell subclass, sample id	RAB25 KRT18 SYNE1 MSMO1 SNX25 TMEM245 DHCR24	3.61e-07	199	101	7	bbe69e44b7970f57628365ae771790f2b13d0cae
ToppCell	Biopsy_Control_(H.)-Epithelial-AT2\|Biopsy_Control_(H.) / Sample group, Lineage and Cell type	RAB25 KRT18 MSMO1 SNX25 TMEM245 DHCR24 ROS1	3.61e-07	199	101	7	5323d49d3be980605b3e609b7f03bddba6e50e8a
ToppCell	Lung_Parenchyma-Control-Epithelial\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	RAB25 KRT18 SYNE1 MSMO1 SNX25 DHCR24 ROS1	3.73e-07	200	101	7	c2bde99b3bc7a8740441c1a0c1394892b940b857
ToppCell	Lung_Parenchyma-Control-Epithelial-Epithelial\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	RAB25 KRT18 SYNE1 MSMO1 SNX25 DHCR24 ROS1	3.73e-07	200	101	7	3ff9abd5e07780a59d5571da906fa15f00a1d5c2
ToppCell	Parenchyma_Control_(B.)-Epithelial-TX\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	RAB25 KRT18 SYNE1 MSMO1 SNX25 DHCR24 ROS1	3.73e-07	200	101	7	9970e9bde6aa2ff3aef60dcb065ff15b7463e147
ToppCell	3'-Child09-12-SmallIntestine-Epithelial-mature_enterocytic-Paneth\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RAB25 KRT18 RIIAD1 SLC28A3 SMOC2 OVGP1	1.77e-06	160	101	6	6005948e400e781cdb876ba350b3ec8991e3945f
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TRHDE RNF144B SYNE1 EML6 SMOC2 PTPRT	3.06e-06	176	101	6	327a3e81b724252e36d786de92a3ffd721ea6d7b
ToppCell	Children_(3_yrs)-Immune-interstitial_macrophage_(C1Q_positive)-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	PLB1 ABCA1 EYA2 PLEKHG5 STAB1 SCN9A	4.08e-06	185	101	6	8207f9eff113eed429e961748c6b17d672a13b33
ToppCell	3'-Child09-12-SmallIntestine-Hematopoietic-B_cells-DZ_GC_cell\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RNF144B AICDA EML6 GLRA3 TCL1A PRKCB	4.48e-06	188	101	6	9a10536afa2dea34c78421d36564cfd8252afe45
ToppCell	COVID-19-kidney-CD-PC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	TRHDE EML6 TOP6BL FAM83B PRKAG2 WDR72	4.48e-06	188	101	6	8f9996c3f3b27efaaae8960a66af77412de9c7ef
ToppCell	COVID-19-Epithelial-Ionocytes\|COVID-19 / Condition, Lineage and Cell class	KRT18 EYA2 FAM83B PRKAA2 ATP6V1C2 WDR72	4.48e-06	188	101	6	a581cb9528d0febbf3addbb4f6bc140f91a584e6
ToppCell	facs-Lung-EPCAM-18m-Epithelial-Basal\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RAB25 KRT18 EYA2 FAM83B ATP6V1C2 WDR72	4.62e-06	189	101	6	783c1db856f2defe6f3b8748dd0bc29a8102f6d1
ToppCell	facs-Lung-EPCAM-18m-Epithelial-respiratory_basal_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RAB25 KRT18 EYA2 FAM83B ATP6V1C2 WDR72	4.62e-06	189	101	6	88b72fafbe58463543e0818f27f3dd9e5b4d34d2
ToppCell	Mid-temporal_gyrus_(MTG)-Non-neuronal-Endothelial_Myeloid\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ARHGAP15 ITGB2 STAB1 UBA7 SAMD9L IRAK3	4.62e-06	189	101	6	e9fe8d17f4b7cca9bbf3655047e27b2fec5060c1
ToppCell	Children_(3_yrs)-Immune-interstitial_macrophage_(C1Q_positive)\|Children_(3_yrs) / Lineage, Cell type, age group and donor	PLB1 ABCA1 EYA2 STAB1 SCN9A KCNMA1	4.76e-06	190	101	6	f573fef3762a30c38cf8fa7f45df0ffbb49dc873
ToppCell	LV-08._Macrophage\|World / Chamber and Cluster_Paper	ARHGAP15 STAB1 SCN9A KCNMA1 MED12L PRKCB	4.91e-06	191	101	6	e7a0bc46ba9ba772636a583f3387748418e18832
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PLB1 ABCA1 ARHGAP15 ITGB2 STAB1 KCNMA1	4.91e-06	191	101	6	51f5af610983aa73b9f4ece6f27d281ebff89a04
ToppCell	facs-Aorta-Heart-3m-Mesenchymal-leukocyte\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RAB25 GARIN1A KRT18 KCNMA1 ATP6V1C2 WDR72	4.91e-06	191	101	6	116fba9badea093e11f370996247cca0e4c02e8f
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PLB1 ABCA1 ARHGAP15 ITGB2 STAB1 KCNMA1	4.91e-06	191	101	6	8fd6bdc9d2b1c8d364221d7bc68d03921b668ab5
ToppCell	(7)_Epithelial-E_(AT2)\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	RAB25 KRT18 MSMO1 SNX25 DHCR24 ROS1	4.91e-06	191	101	6	0fc8d109d5c50957ceef5b8b8b818b0c598b1bbe
ToppCell	RV-08._Macrophage\|World / Chamber and Cluster_Paper	ARHGAP15 STAB1 BUB1B SCN9A KCNMA1 PRKCB	5.06e-06	192	101	6	a1b5dc5beb97a23729b97b54fb4574d10d8fbfb3
ToppCell	LV-08._Macrophage\|LV / Chamber and Cluster_Paper	ARHGAP15 STAB1 SCN9A KCNMA1 PRKCB IRAK3	5.06e-06	192	101	6	7be12d580aaf2f2f1562203fcad3a44639b8c5a6
ToppCell	COVID-19-Heart-Macrophage\|Heart / Disease (COVID-19 only), tissue and cell type	ARHGAP15 ITGB2 STAB1 SCN9A KCNMA1 PRKCB	5.36e-06	194	101	6	f09675cd472200363c458952f00d2e41990800ee
ToppCell	5'-Adult-SmallIntestine-Hematopoietic-Myeloid-Macrophages\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RNF144B ABCA1 ITGB2 STAB1 KCNMA1 IRAK3	5.36e-06	194	101	6	7c7091de47359760003e910cfbe63db5c99410d6
ToppCell	Adult-Immune-interstitial_macrophage_(C1Q_positive)-D231\|Adult / Lineage, Cell type, age group and donor	ABCA1 ARHGAP15 ITGB2 STAB1 PRKCB PRKAG2	5.36e-06	194	101	6	800d3d7a9e864d2d6a100a4e4af22f45d5790a8d
ToppCell	LA-08._Macrophage\|World / Chamber and Cluster_Paper	RNF144B ARHGAP15 STAB1 SCN9A KCNMA1 IRAK3	5.36e-06	194	101	6	c1805572bcc11b1cd29083329d7b5911489fb758
ToppCell	COVID-19-Myeloid-Monocyte-derived_macrophages\|COVID-19 / group, cell type (main and fine annotations)	RNF144B ABCA1 STAB1 KCNMA1 IRAK3 PRKAG2	5.52e-06	195	101	6	c172c5599379c29123340621a36bfb1fc90c2115
ToppCell	(7)_Epithelial-A_(AT2)\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	RAB25 KRT18 MSMO1 SNX25 DHCR24 ROS1	5.52e-06	195	101	6	c9a6c65ee18d83bf34a4713d306a6e30db1325c2
ToppCell	LA-08._Macrophage\|LA / Chamber and Cluster_Paper	RNF144B ARHGAP15 STAB1 SCN9A KCNMA1 PRKCB	5.52e-06	195	101	6	5e1d5bdb8874091f5a2b1d0a8cc9008165718a97
ToppCell	human_hepatoblastoma-Inflammatory_Monocytes\|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)	RNF144B ARHGAP15 KCNMA1 PRKCB IRAK3 PRKAG2	5.52e-06	195	101	6	ba7f85e5307d96ac5ad7c952f8d094db9ca1790c
ToppCell	Control-Myeloid-ncMonocyte\|World / Disease state, Lineage and Cell class	RNF144B ABCA1 ARHGAP15 PRKCB IRAK3 PRKAG2	5.52e-06	195	101	6	b4444b67a709e82b8e2ee510924c3152cb88b051
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PLB1 ABCA1 ARHGAP15 STAB1 KCNMA1 PRKCB	5.52e-06	195	101	6	34a9462f4e843f3065cc58c17ad71c1b5b836ae1
ToppCell	3'-Parenchyma_lung-Epithelial\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SYNE1 MSMO1 SNX25 TMEM245 DHCR24 ROS1	5.52e-06	195	101	6	eec187c087e432417bc346c5d3ead72f58bf3215
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SYNE1 MSMO1 SNX25 TMEM245 DHCR24 ROS1	5.69e-06	196	101	6	7e5addaa844e66f8160e05858c341866a80aed23
ToppCell	Adult-Immune-monocyte\|Adult / Lineage, Cell type, age group and donor	RNF144B ARHGAP15 ITGB2 STAB1 PRKCB IRAK3	5.69e-06	196	101	6	3ef193c5180de3137daf886492e74fc574bc9767
ToppCell	Control-Myeloid-Macrophage\|Control / Disease state, Lineage and Cell class	RNF144B ABCA1 STAB1 KCNMA1 IRAK3 PRKAG2	5.69e-06	196	101	6	e2c2a30fa3ee3034fbde5335be169e880dde622d
ToppCell	COVID-19-Myeloid-Transitioning_MDM\|COVID-19 / group, cell type (main and fine annotations)	RNF144B ABCA1 STAB1 KCNMA1 IRAK3 PRKAG2	5.69e-06	196	101	6	4929cfed1f150c1fde4d79cb49895c2ea467a18f
ToppCell	(7)_Epithelial-B_(AT2)\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	RAB25 KRT18 MSMO1 SNX25 DHCR24 ROS1	5.69e-06	196	101	6	345d4cc062b43bca9d506fbf23363469a9ba496f
ToppCell	cellseq-Epithelial-Epithelial_Alveolar\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	KRT18 MSMO1 SNX25 TMEM245 DHCR24 ROS1	5.69e-06	196	101	6	a7cbe66ebd8931ef2b8ff26a42afce0ad1c48f17
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	RNF144B ABCA1 ARHGAP15 STAB1 PRKCB IRAK3	5.86e-06	197	101	6	8af4a1e35ce9fb4ea3d26ab619599efb7eac43a5
ToppCell	COVID-19-lung-Macrophage_LDB2hi_OSMRhi_YAP1hi\|COVID-19 / Disease (COVID-19 only), tissue and cell type	RNF144B ARHGAP15 STAB1 KCNMA1 PRKCB IRAK3	5.86e-06	197	101	6	e42910a653a1b5bd90c090e9665a84871ed2873f
ToppCell	343B-Epithelial_cells-Epithelial-B_(AT2)\|343B / Donor, Lineage, Cell class and subclass (all cells)	RAB25 KRT18 MSMO1 SNX25 DHCR24 ROS1	5.86e-06	197	101	6	f3ca63c7902d7530a29a85eb54f69b303031d150
ToppCell	Fetal_29-31_weeks-Immune-monocyte-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	RNF144B ARHGAP15 ITGB2 STAB1 PRKCB IRAK3	5.86e-06	197	101	6	8b9a88fb671d5c2b25d291c851e2b8a478f2610c
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid-Monocytic-Monocyte-derived_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	RNF144B PLB1 ARHGAP15 ITGB2 PRKCB IRAK3	5.86e-06	197	101	6	dea1d29154c585ab588e50b83c7c8de7fe24d2d4
ToppCell	IPF-Myeloid-Macrophage\|IPF / Disease state, Lineage and Cell class	RNF144B ABCA1 ITGB2 KCNMA1 IRAK3 PRKAG2	5.86e-06	197	101	6	a2ffb33c7cad6be43cbb8ed9a91338923cc07db4
ToppCell	343B-Epithelial_cells-Epithelial-B_(AT2)-\|343B / Donor, Lineage, Cell class and subclass (all cells)	RAB25 KRT18 MSMO1 SNX25 DHCR24 ROS1	5.86e-06	197	101	6	f98720cab066579fdac3ba24fb6fe4c5759dae4e
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid-Monocytic\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	RNF144B PLB1 ARHGAP15 ITGB2 PRKCB IRAK3	5.86e-06	197	101	6	72cd61b868d57862ec9c230ea68913d3829b0f2b
ToppCell	distal-Epithelial-Alveolar_Epithelial_Type_2-1\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	RAB25 KRT18 MSMO1 SNX25 DHCR24 ROS1	6.03e-06	198	101	6	19eefd05573fbaed654af52bf0f8a26092b8b229
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PLB1 ARHGAP15 ITGB2 STAB1 PRKCB IRAK3	6.03e-06	198	101	6	96883ad8e189a46ed5b7eaafc0543e53682d26ed
ToppCell	COVID-19-Myeloid\|COVID-19 / group, cell type (main and fine annotations)	RNF144B ABCA1 STAB1 KCNMA1 IRAK3 PRKAG2	6.03e-06	198	101	6	33f0a919188a67d2a876b52c61a1cec2c9747969
ToppCell	AT2_cells-Donor_04\|World / lung cells shred on cell class, cell subclass, sample id	KRT18 SYNE1 MSMO1 SNX25 TMEM245 DHCR24	6.03e-06	198	101	6	8a1f984e46f4fa5be33027b9dbaa2ca060a2245d
ToppCell	COVID-19-kidney-Macrophages\|kidney / Disease (COVID-19 only), tissue and cell type	ABCA1 ARHGAP15 ITGB2 STAB1 PRKCB IRAK3	6.03e-06	198	101	6	161324541fe5da5cbb58142ea94fefd39b7dfb04
ToppCell	Immune-monocyte\|World / Lineage, Cell type, age group and donor	RNF144B ARHGAP15 ITGB2 STAB1 PRKCB IRAK3	6.03e-06	198	101	6	d3622da252fd580f1dc5c7478a8e23df5ec083cf
ToppCell	COPD-Myeloid-Macrophage\|COPD / Disease state, Lineage and Cell class	RNF144B ABCA1 STAB1 KCNMA1 IRAK3 PRKAG2	6.21e-06	199	101	6	4b9c53fb4f44190d2f6ad4d52b13be01ebe4955e
ToppCell	COVID-19-lung\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ABCA1 ARHGAP15 STAB1 SAMD9L PRKCB IRAK3	6.21e-06	199	101	6	155b03b859157013e9142e9248551369127d9204
ToppCell	5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SYNE1 MSMO1 SNX25 TMEM245 DHCR24 ROS1	6.21e-06	199	101	6	2dc33804f6691d7c9682e6c9b885e945fb97fc36
ToppCell	Lung_Parenchyma-Control-Epithelial-Epithelial-AT2-2-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	RAB25 KRT18 MSMO1 SNX25 DHCR24 ROS1	6.39e-06	200	101	6	3c251ad03fbbdae91dfd9037880ba43adbb03807
ToppCell	Children_(3_yrs)-Immune-monocyte-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	RNF144B ARHGAP15 STAB1 PRKCB IRAK3 ARHGAP27	6.39e-06	200	101	6	881ab995c90d75fd987d6e8f1f926a4bfcc4235f
ToppCell	Lung_Parenchyma-Control-Epithelial-Epithelial-AT2-2\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	RAB25 KRT18 MSMO1 SNX25 DHCR24 ROS1	6.39e-06	200	101	6	c905451425d1c24773bb0ca69bcf0309b277d2f1
ToppCell	Lung_Parenchyma-Control-Epithelial-Epithelial-AT2-1-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	RAB25 KRT18 MSMO1 SNX25 DHCR24 ROS1	6.39e-06	200	101	6	65c83a3f6ee2a10bcb5b95076696232c6373a7b4
ToppCell	Lung_Parenchyma-Control-Epithelial-Epithelial-AT2-1\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	RAB25 KRT18 MSMO1 SNX25 DHCR24 ROS1	6.39e-06	200	101	6	40e969883bc302e8fbc6b6ab9814529dc1472902
ToppCell	Parenchyma_Control_(B.)-Epithelial-TX-AT2-1\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	RAB25 KRT18 MSMO1 SNX25 DHCR24 ROS1	6.39e-06	200	101	6	ad9cdc82a647d379abc713a56db0e11bb6494106
ToppCell	Lung_Parenchyma-Severe-Epithelial-Epithelial-AT2-2\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	RAB25 KRT18 SNX25 TMEM245 DHCR24 ROS1	6.39e-06	200	101	6	acc771a902cf2f060c3eb9aedb72a256f5778a6c
ToppCell	Parenchyma_COVID-19-Epithelial-TX-AT2-2\|Parenchyma_COVID-19 / Sample group, Lineage and Cell type	RAB25 KRT18 SNX25 TMEM245 DHCR24 ROS1	6.39e-06	200	101	6	ceb613ac6cdf0e3e6bb3f04d89034e18a524cefb
ToppCell	Parenchyma_Control_(B.)-Epithelial-TX-AT2-2\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	RAB25 KRT18 MSMO1 SNX25 DHCR24 ROS1	6.39e-06	200	101	6	35c05cae30cd6b323d2662f1396ddeab08bc75fc
ToppCell	Lung_Parenchyma-Severe-Epithelial-Epithelial-AT2-2-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	RAB25 KRT18 SNX25 TMEM245 DHCR24 ROS1	6.39e-06	200	101	6	eb44d1f80ecaac3a022cd04ab16dc36151e45488
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	RGPD4 SLC6A2 DEPDC5 ATP6V1C2 WDR72	1.47e-05	136	101	5	7cd22169fb71c6caf9feb203ad98be8480a54fba
ToppCell	LPS-IL1RA+antiTNF-Myeloid-Dendritic_cells-Monocytes-Macrophages\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PLB1 ARHGAP15 ITGB2 KCNMA1 PRKCB	2.07e-05	146	101	5	b76110b159acd27a2c8d6a9f98336608ace1ec12
ToppCell	saliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_B\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	AICDA RINT1 MSMO1 MED12L GALNTL5	2.28e-05	149	101	5	14d2e8cab97108d8fa94e540c1957b73ed32dc73
ToppCell	saliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_B-B_cell\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	AICDA RINT1 MSMO1 MED12L GALNTL5	2.28e-05	149	101	5	54c9c6282f5f5de43dfaf2972fab3e3dcf9838a3
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRHDE PLB1 GLRA3 PTPRT KCNMA1	3.21e-05	160	101	5	c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRHDE PLB1 GLRA3 PTPRT KCNMA1	3.21e-05	160	101	5	25c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell	Children_(3_yrs)-Immune-dendritic_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SLC41A2 TCL1A SCN9A MED12L PRKCB	3.41e-05	162	101	5	86a0b9dabd150dc993bfc0f3344804de7f8e4042
ToppCell	E16.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ATP7B TOP6BL TMEM245 ROS1 ATP6V1C2	3.41e-05	162	101	5	8e0f03fcc25b2ea777e8478fbf771699cf93719c
ToppCell	3'-Pediatric_IBD-SmallIntestine-Hematopoietic-B_cells-DZ_GC_cell\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RNF144B AICDA EML6 GLRA3 TCL1A	3.41e-05	162	101	5	3e15b3e97a2ade86d0cb0ab15fccb9a2e2e27dd4
ToppCell	E16.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ATP7B TOP6BL TMEM245 ROS1 ATP6V1C2	3.41e-05	162	101	5	e0417f1242edf71934fe62bccc55c4678f7ff4ac
ToppCell	3'-Child04-06-SmallIntestine-Epithelial-mature_enterocytic-Paneth\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RAB25 KRT18 SLC28A3 SMOC2 WDR72	4.06e-05	168	101	5	3e3f611e9bbec8224264666be14a4e7db343070e
ToppCell	3'-Adult-SmallIntestine-Hematopoietic-B_cells-Cycling_B_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	AICDA EML6 TCL1A MED12L PRKCB	4.17e-05	169	101	5	203971cceeba150d0e8891c92662545e84c77837
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Myeloid-Macrophage-macrophage,_alveolar-Macro_c3-EREG\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	RNF144B ABCA1 STAB1 PRKCB IRAK3	4.29e-05	170	101	5	9ac1ef57f14418a5dd2aa16861c3df698c28f5ed
ToppCell	P15-Epithelial-alveolar_epithelial_cell-type_II_pneumocyte\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	RAB25 ATP7B KRT18 SNX25 ATP6V1C2	4.29e-05	170	101	5	6c0619cbe2f01a6de18da0a137f92bda0cbdf075
ToppCell	Ionocyte\|World / Class top	SMOC2 SLC6A2 KL KCNMA1 ATP6V1C2	4.29e-05	170	101	5	d2e592f2a679e6a8d32f2b752d9a3c493e50ced4
ToppCell	Smart-seq2-tissue-resident_(Smart-seq2)-myeloid-myeloid_dendritic-CD1c-positive_myeloid_dendritic_cell\|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	RNF144B ATP6V1C1 ABCA1 SLC41A2 USP12	4.29e-05	170	101	5	cc66ac6846c58be9493eb270644ee3ce0f86cfea
Disease	developmental and epileptic encephalopathy 87 (implicated_via_orthology)	CDK8 CDK19	1.05e-05	2	96	2	DOID:0112221 (implicated_via_orthology)
Disease	maximal midexpiratory flow rate	OCA2 MED12L GALNTL5	3.65e-05	20	96	3	EFO_0004313
Disease	creatinine measurement, glomerular filtration rate	DNAJC16 THADA PRKAG2 UBE2Q2 WDR72	4.12e-05	117	96	5	EFO_0004518, EFO_0005208
Disease	Colorectal Carcinoma	ABCA1 ATP7B KALRN SYNE1 RPS6KB1 PTPRT KL OVGP1 BUB1B PRKCB	9.77e-05	702	96	10	C0009402
Disease	urinary pH measurement	KALRN WDR72	1.04e-04	5	96	2	EFO_0010136
Disease	phospholipase B-like 1 measurement	COPS4 PLOD1	1.04e-04	5	96	2	EFO_0802865
Disease	glomerular filtration rate, creatine measurement	PRKAG2 WDR72	1.56e-04	6	96	2	EFO_0005208, EFO_0010472
Disease	gout	ABCA1 CNIH2 SLC28A3 PRKAG2 UBE2Q2	4.60e-04	196	96	5	EFO_0004274
Disease	vascular brain injury measurement, vascular brain injury	ARHGAP15 SEZ6L	7.98e-04	13	96	2	EFO_0006791, EFO_0006800
Disease	Hereditary Motor and Sensory-Neuropathy Type II	FIG4 SCN9A	7.98e-04	13	96	2	C0270914
Disease	5-oxoproline measurement	GPAA1 SLC28A3	1.22e-03	16	96	2	EFO_0010988
Disease	Abnormal behavior	CDK8 MED12L	1.22e-03	16	96	2	C0233514
Disease	Microcephaly	BUB1B GPT2 STAG2	1.37e-03	67	96	3	C0025958
Disease	triacylglycerol 56:9 measurement	PRKCB MAGEC1	1.38e-03	17	96	2	EFO_0010436
Disease	epilepsy (implicated_via_orthology)	KALRN SCN9A KCNMA1 DEPDC5	2.01e-03	163	96	4	DOID:1826 (implicated_via_orthology)
Disease	cystatin C measurement	KALRN DNAJC16 RPS6KB1 PRKAG2 UBE2Q2 WDR72	2.04e-03	402	96	6	EFO_0004617
Disease	Colorectal Neoplasms	ABCA1 ATP7B SYNE1 BUB1B PRKCB	2.14e-03	277	96	5	C0009404
Disease	triacylglycerol 54:8 measurement	PTPRT PRKCB	2.53e-03	23	96	2	EFO_0010426
Disease	urate measurement	ABCA1 DNAJC16 CNIH2 TOP6BL PTPRT STAB1 PRKAG2 VPS51 UBE2Q2	2.57e-03	895	96	9	EFO_0004531
Disease	Liver Failure, Acute	ATP7B KRT18	2.76e-03	24	96	2	C0162557
Disease	primary biliary cholangitis (is_marker_for)	ABCA1 KRT18	2.99e-03	25	96	2	DOID:12236 (is_marker_for)
Disease	triacylglycerol 56:5 measurement	PRKCB MAGEC1	3.24e-03	26	96	2	EFO_0010432
Disease	diet measurement, bilirubin measurement	PTPRT SLC6A2	3.24e-03	26	96	2	EFO_0004570, EFO_0008111
Disease	myeloperoxidase measurement	SMG8 THADA	3.24e-03	26	96	2	EFO_0005243

Protein segments in the cluster

Peptide	Gene	Start	Entry
IIRYLSEEKDFLPWH	TRHDE	741	Q9UKU6
HLLLFKEHLQVFWDG	BUB1B	961	O60566
IHFAWEEKLFLLADE	GPT2	286	Q8TD30
VQIYELEEHKIETWR	PRKAG2	336	Q9UGJ0
LEEHKIETWRELYLQ	PRKAG2	341	Q9UGJ0
LFDYAEHDLWHIIKF	CDK19	96	Q9BWU1
FVFIALGRWLEHLAK	ATP7B	771	P35670
LDFEWKVVNAYHLRV	PRKAA2	426	P54646
EEHIWFYARLKGLSE	ABCA1	991	O95477
HVELLFLRYISDWDL	AICDA	56	Q9GZX7
AVVERWLKELYDHAE	RAB25	101	P57735
EIILHRVEWATLLFF	OCA2	671	Q04671
FYWVIYKILRHEDIH	GLRA3	446	O75311
LKFEREVHLDPYRTW	RNF144B	106	Q7Z419
AVIEDTWHYFLHRLL	MSMO1	146	Q15800
RKWFEVAFVAEELVH	DEPDC5	1291	O75140
WSHYFKIIEDLRAQI	KRT18	126	P05783
WTLKLLQFLYHRDED	KIAA0100	301	Q14667
LLKVEHFSWVFLDDV	KIAA0100	871	Q14667
LEKHEYLTWILDVLE	MED12L	246	Q86YW9
RELLTKVWVQEHYLE	MAGEC1	1041	O60732
HIVFVGSIEYLKREW	KCNMA1	876	Q12791
LELLHWFKEEFFHWV	NGLY1	231	Q96IV0
WAKDIVFLVTEHDLL	GPAA1	176	O43292
EWYRVAIDILIEHGL	FAM83B	26	Q5T0W9
LEHLDRVLYEWFLGK	JRK	86	O75564
IRQHLASIYEKEEDW	COPS4	106	Q9BT78
QLFIKHERKLHIYVW	KALRN	2006	O60229
LDKHREWLEYLLEFA	DNAJC16	661	Q9Y2G8
FFRHINWEELLARKV	RPS6KB1	351	P23443
HILDKFILKVLDRHW	LHX4	36	Q969G2
VEEIKRHLFFANIDW	RPS6KA6	321	Q9UK32
ERDIKEHAFFRYIDW	PRKCB	591	P05771
EHAFFRYIDWEKLER	PRKCB	596	P05771
WKRFLSELEVLLLFH	IRAK3	206	Q9Y616
LEHEASDLVEIYLWK	CHRDL2	356	Q6WN34
VDLENVWLHFIREFI	PLOD2	616	O00469
IGFEREWHKFLLEYI	PLOD1	606	Q02809
KLWHLDPDVEYEIRV	PTPRT	346	O14522
VIWKALIHLSDLREY	ITGB2	721	P05107
LDHLRVYWQELLDLH	PDP2	206	Q9P2J9
YWNLALIFHRKAEDI	RGPD3	681	A6NKT7
DIIKSTVHRDWLLYI	FIG4	236	Q92562
KGLEFVLIHQRWVFV	DHCR24	21	Q15392
IYHFRLLKDEIVDHW	NDUFAF1	91	Q9Y375
YDTTEWHEDLKVILR	DNAH7	2371	Q8WXX0
LRLVHVWLDEYKEQF	GALNTL5	381	Q7Z4T8
LYLELTRRWAEHFIK	MANEAL	436	Q5VSG8
VYLWDVHHSKRLIKV	KL	546	Q9UEF7
GDVYVWKDHFLIRLV	EML6	1576	Q6ZMW3
LWHFILELLQKEEFR	ETV3L	41	Q6ZN32
LELLQKEEFRHVIAW	ETV3L	46	Q6ZN32
LFDYAEHDLWHIIKF	CDK8	96	P49336
ILWYFEHQLKHLVAE	CEBPZ	331	Q03701
EIWLAIHHFEKAVTL	OGT	206	O15294
HDRWTFLFLIEELLF	OVGP1	151	Q12889
YWNLALIFHRKAEDI	RGPD1	671	P0DJD0
EWHHRLILFVIFLVL	OR10J4	21	P0C629
FVWDLDETIIIFHSL	EYA2	271	O00167
HEKHPEIVFQFWVRL	GARIN1A	156	Q6NXP2
VDFTLREFLWQHVEL	SMG8	406	Q8ND04
HIDFYRLKEATVWID	SLC6A2	296	P23975
FIAWIHVKALRVFVE	ATP6V1C1	291	P21283
FIAWIHIKALRVFVE	ATP6V1C2	336	Q8NEY4
YWNLALIFHRKAEDI	RGPD4	681	Q7Z3J3
FFVELTESLLRLEWH	THADA	436	Q6YHU6
WKIHVGEEKRIFLDI	SEZ6L	656	Q9BYH1
VAVFEILRFLIIHWK	TOP6BL	6	Q8N6T0
ELHRLETILKHWTRY	SYNE1	6786	Q8NF91
VFLHERELWLKFHEV	TBX5	56	Q99593
EKYLRTHKEVEWLIS	RIIAD1	36	A6NNX1
LYHLLLEDFWEIARQ	SNX25	31	Q9H3E2
HRSKWLESYLLHLEE	PTGIS	251	Q16647
HLDFLKEIKWFAVLE	SAMD9L	431	Q8IVG5
WEDVHVITGALKLFF	ARHGAP27	761	Q6ZUM4
SDIDFIILDWFHAIK	ARHGAP15	171	Q53QZ3
VFVELWLKNRTLDEH	PRAMEF25	151	A6NGN4
YKIVEHSWFESFIVL	SCN9A	1186	Q15858
ERHLVYERWDFLCKL	SETD6	331	Q8TBK2
HWEVFRKVTEVFILV	SLC41A2	186	Q96JW4
VAYEHLSKWIHLRKE	SLC28A3	521	Q9HAS3
RIHFQEDWKIITLFI	PLB1	496	Q6P1J6
ELYKAHEWARAIIES	SCRN1	346	Q12765
FWRLVYHIKIDGVED	TCL1A	91	P56279
IFFAIWHIIAFDELK	CNIH1	21	O95406
IFFVIWHIIAFDELR	CNIH2	21	Q6PI25
IFFAIWHIIAFDELR	CNIH3	21	Q8TBE1
WLISEDKREYAVHIA	XIRP2	2811	A4UGR9
VWELLHTEASYIRKL	PLEKHG5	341	O94827
QLYLWRFVADEELVH	VPS51	736	Q9UID3
HERFRIVSWKLDELH	UBE2Q2	21	Q8WVN8
QIEEIERHLAYLKWI	RINT1	151	Q6NUQ1
ERHLAYLKWISQIEE	RINT1	156	Q6NUQ1
TLQWARHEFEELFRL	UBA7	611	P41226
DWIESYKHDRDIALL	STAG2	101	Q8N3U4
TLEERVVHWYFKLLD	SMOC2	346	Q9H3U7
EVSRHLEFYLLWTHK	PWP2	811	Q15269
IVKSHDFWLLFDDDI	USP12	321	O75317
VILWDIFTEEILHKF	WDR72	491	Q3MJ13
WLYHEDHRDKLAAIL	STAB1	1781	Q9NY15
AHWEVVERILFIYAK	TBC1D13	206	Q9NVG8
IDWISRHLYFALKES	ROS1	1231	P08922
IEKQVLELWDRLYHS	TMEM245	556	Q9H330
EDVLYFWKHSTVLDI	SLC25A23	151	Q9BV35
DEHLDIRLDAFWLKV	UHRF1BP1	576	Q6BDS2
KLWVLETKEVYRHFT	WDR43	191	Q15061
DLIVDIWVSVRFFHE	XKR9	21	Q5GH70
YFQLERDKIHTFWEI	GAS8	51	O95995