Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	voltage-gated sodium channel activity	SCN8A SCN9A TPCN1	1.01e-04	26	70	3	GO:0005248
GeneOntologyCellularComponent	dynactin complex	ACTR1B ACTR1A	3.14e-04	8	71	2	GO:0005869
GeneOntologyCellularComponent	ciliary membrane	SLC9C1 PDE6A EVC PTCH1	3.47e-04	98	71	4	GO:0060170
Domain	Arp1	ACTR1B ACTR1A	1.31e-05	2	68	2	IPR029909
Domain	Na_trans_cytopl	SCN8A SCN9A	1.94e-04	6	68	2	PF11933
Domain	Na_trans_cytopl	SCN8A SCN9A	1.94e-04	6	68	2	IPR024583
Domain	Mob1_phocein	MOB1B MOB1A	2.71e-04	7	68	2	PF03637
Domain	MOB_kinase_act_fam	MOB1B MOB1A	2.71e-04	7	68	2	IPR005301
Domain	-	MOB1B MOB1A	2.71e-04	7	68	2	1.20.140.30
Domain	Mob1_phocein	MOB1B MOB1A	2.71e-04	7	68	2	SM01388
Domain	Na_channel_asu	SCN8A SCN9A	5.77e-04	10	68	2	IPR001696
Domain	Interfer-bind	IL10RB IFNAR1	5.77e-04	10	68	2	PF09294
Domain	Na_trans_assoc	SCN8A SCN9A	5.77e-04	10	68	2	IPR010526
Domain	Interferon/interleukin_rcp_dom	IL10RB IFNAR1	5.77e-04	10	68	2	IPR015373
Domain	Na_trans_assoc	SCN8A SCN9A	5.77e-04	10	68	2	PF06512
Domain	FN3	IL10RB IL13RA2 DSCAM CMYA5 IFNAR1	7.90e-04	199	68	5	PS50853
Domain	Ion_trans_dom	SLC9C1 SCN8A SCN9A TPCN1	7.94e-04	114	68	4	IPR005821
Domain	Ion_trans	SLC9C1 SCN8A SCN9A TPCN1	7.94e-04	114	68	4	PF00520
Domain	Tissue_fac	IL10RB IFNAR1	8.42e-04	12	68	2	PF01108
Domain	Tissue_factor	IL10RB IFNAR1	8.42e-04	12	68	2	IPR001187
Domain	FN3_dom	IL10RB IL13RA2 DSCAM CMYA5 IFNAR1	9.84e-04	209	68	5	IPR003961
Domain	Channel_four-helix_dom	SCN8A SCN9A TPCN1	1.17e-03	57	68	3	IPR027359
Domain	-	SCN8A SCN9A TPCN1	1.17e-03	57	68	3	1.20.120.350
Domain	Actin_CS	ACTR1B ACTR1A	1.52e-03	16	68	2	IPR004001
Domain	ACTINS_2	ACTR1B ACTR1A	1.71e-03	17	68	2	PS00432
Domain	Actin/actin-like_CS	ACTR1B ACTR1A	1.92e-03	18	68	2	IPR020902
Domain	ACTINS_ACT_LIKE	ACTR1B ACTR1A	2.15e-03	19	68	2	PS01132
Domain	Keratin_2_head	KRT5 KRT84	3.42e-03	24	68	2	IPR032444
Domain	Keratin_2_head	KRT5 KRT84	3.42e-03	24	68	2	PF16208
Domain	Keratin_II	KRT5 KRT84	4.01e-03	26	68	2	IPR003054
Domain	FN3	IL10RB DSCAM CMYA5 IFNAR1	4.63e-03	185	68	4	SM00060
Domain	Actin	ACTR1B ACTR1A	5.67e-03	31	68	2	IPR004000
Domain	Actin	ACTR1B ACTR1A	5.67e-03	31	68	2	PF00022
Domain	ACTIN	ACTR1B ACTR1A	5.67e-03	31	68	2	SM00268
Pathway	REACTOME_SIGNALING_BY_HIPPO	YAP1 MOB1B MOB1A	6.11e-05	20	55	3	MM14813
Pathway	REACTOME_SIGNALING_BY_HIPPO	YAP1 MOB1B MOB1A	6.11e-05	20	55	3	M591
Pubmed	YAP1 is a potent driver of the onset and progression of oral squamous cell carcinoma.	YAP1 MOB1B MOB1A	8.13e-08	5	71	3	32206709
Pubmed	Hippo-TAZ signaling is the master regulator of the onset of triple-negative basal-like breast cancers.	YAP1 MOB1B MOB1A	1.62e-07	6	71	3	35858357
Pubmed	Endogenous YAP1 activation drives immediate onset of cervical carcinoma in situ in mice.	YAP1 MOB1B MOB1A	1.62e-07	6	71	3	32716083
Pubmed	YAP determines the cell fate of injured mouse hepatocytes in vivo.	YAP1 MOB1B MOB1A	1.62e-07	6	71	3	28681838
Pubmed	Dysregulated YAP1/TAZ and TGF-β signaling mediate hepatocarcinogenesis in Mob1a/1b-deficient mice.	YAP1 MOB1B MOB1A	4.53e-07	8	71	3	26699479
Pubmed	Systematic analysis of human protein complexes identifies chromosome segregation proteins.	DHX15 TTLL12 ACTR1B ACTR1A EDEM3 PPP2R5E GTF3C1 CLU MOB1B MOB1A RCN2 SNRNP200 PPL	5.44e-07	1155	71	13	20360068
Pubmed	Depletion of MOB1A/B causes intestinal epithelial degeneration by suppressing Wnt activity and activating BMP/TGF-β signaling.	MOB1B MOB1A	4.11e-06	2	71	2	30349003
Pubmed	Cancer susceptibility and embryonic lethality in Mob1a/1b double-mutant mice.	MOB1B MOB1A	4.11e-06	2	71	2	23143302
Pubmed	Hedgehog receptors exert immune-surveillance roles in the epidermis across species.	KRT5 PTCH1	4.11e-06	2	71	2	37527037
Pubmed	Beta-centractin: characterization and distribution of a new member of the centractin family of actin-related proteins.	ACTR1B ACTR1A	4.11e-06	2	71	2	7696711
Pubmed	Human Mob1 proteins are required for cytokinesis by controlling microtubule stability.	MOB1B MOB1A	4.11e-06	2	71	2	22454515
Pubmed	Sodium channel slow inactivation interferes with open channel block.	SCN8A SCN9A	4.11e-06	2	71	2	27174182
Pubmed	Stress-induced retrotranslocation of clusterin/ApoJ into the cytosol.	CLU SYVN1	4.11e-06	2	71	2	17451556
Pubmed	IFN-mediated negative feedback supports bacteria class-specific macrophage inflammatory responses.	IL10RB IFNAR1	4.11e-06	2	71	2	31385572
Pubmed	MOB1-YAP1/TAZ-NKX2.1 axis controls bronchioalveolar cell differentiation, adhesion and tumour formation.	YAP1 MOB1B MOB1A	6.51e-06	18	71	3	28346423
Pubmed	EGFR Regulates the Hippo pathway by promoting the tyrosine phosphorylation of MOB1.	MOB1B MOB1A	1.23e-05	3	71	2	34725466
Pubmed	The human tumour suppressor LATS1 is activated by human MOB1 at the membrane.	MOB1B MOB1A	1.23e-05	3	71	2	16674920
Pubmed	Hedgehog signaling induces osteosarcoma development through Yap1 and H19 overexpression.	YAP1 PTCH1	1.23e-05	3	71	2	24141783
Pubmed	Expression of alternatively spliced sodium channel alpha-subunit genes. Unique splicing patterns are observed in dorsal root ganglia.	SCN8A SCN9A	1.23e-05	3	71	2	15302875
Pubmed	GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region.	EDEM3 EHF SNRPC	1.60e-05	24	71	3	24871463
Pubmed	Nonsyndromic Retinitis Pigmentosa Overview	PDE6A KLHL7 SNRNP200 ADGRA3	2.36e-05	81	71	4	20301590
Pubmed	PTEN-GSK3β-MOB1 axis controls neurite outgrowth in vitro and in vivo.	MOB1B MOB1A	2.46e-05	4	71	2	30069702
Pubmed	Mechanism of activation of NDR (nuclear Dbf2-related) protein kinase by the hMOB1 protein.	MOB1B MOB1A	2.46e-05	4	71	2	15197186
Pubmed	GART, SON, IFNAR, and CRF2-4 genes cluster on human chromosome 21 and mouse chromosome 16.	IL10RB IFNAR1	2.46e-05	4	71	2	8318737
Pubmed	Aod1 controlling day 3 thymectomy-induced autoimmune ovarian dysgenesis in mice encompasses two linked quantitative trait loci with opposing allelic effects on disease susceptibility.	IL10RB IFNAR1	2.46e-05	4	71	2	12794114
Pubmed	Integrated single-cell analysis defines the epigenetic basis of castration-resistant prostate luminal cells.	KRT5 CLU	2.46e-05	4	71	2	38878775
Pubmed	NRP-1 interacts with GIPC1 and α6/β4-integrins to increase YAP1/∆Np63α-dependent epidermal cancer stem cell survival.	YAP1 NRP1	2.46e-05	4	71	2	29755126
Pubmed	Nrg1 Regulates Cardiomyocyte Migration and Cell Cycle in Ventricular Development.	YAP1 MOB1B MOB1A	2.57e-05	28	71	3	37846569
Pubmed	A high-throughput approach for measuring temporal changes in the interactome.	DHX15 TTLL12 ACTR1B ACTR1A PPP2R5E CLU YAP1 UGDH USP24 RCN2 CMYA5 SNRNP200	3.57e-05	1455	71	12	22863883
Pubmed	A new sodium channel alpha-subunit gene (Scn9a) from Schwann cells maps to the Scn1a, Scn2a, Scn3a cluster of mouse chromosome 2.	SCN9A NEB	4.09e-05	5	71	2	8812438
Pubmed	T851I mutation of human large tumor suppressor 1 disrupts its kinase activity and tumor-suppressor functions.	YAP1 MOB1A	4.09e-05	5	71	2	33141042
Pubmed	Loss of Mob1a/b in mice results in chondrodysplasia due to YAP1/TAZ-TEAD-dependent repression of SOX9.	YAP1 MOB1A	4.09e-05	5	71	2	29511023
Pubmed	Early development of electrical excitability in the mouse enteric nervous system.	SCN8A SCN9A	4.09e-05	5	71	2	22875929
Pubmed	Roles of mammalian sterile 20-like kinase 2-dependent phosphorylations of Mps one binder 1B in the activation of nuclear Dbf2-related kinases.	YAP1 MOB1B	4.09e-05	5	71	2	19919647
Pubmed	DOCK4 and CEACAM21 as novel schizophrenia candidate genes in the Jewish population.	DOCK4 NRP1	4.09e-05	5	71	2	21682944
Pubmed	Characterization and transcriptional analysis of the mouse Chromosome 16 cytokine receptor gene cluster.	IL10RB IFNAR1	4.09e-05	5	71	2	12584606
Pubmed	STAT1 signaling shields T cells from NK cell-mediated cytotoxicity.	IL10RB IFNAR1	4.09e-05	5	71	2	30796216
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	TTLL12 ZNF18 PPP2R5E DSCAM CLU KLHL7 NAP1L2 ZNF214 IFT122 CMYA5 SNRNP200	5.62e-05	1285	71	11	35914814
Pubmed	Contactin regulates the current density and axonal expression of tetrodotoxin-resistant but not tetrodotoxin-sensitive sodium channels in DRG neurons.	SCN8A SCN9A	6.13e-05	6	71	2	16029194
Pubmed	Single-cell transcriptomes of the regenerating intestine reveal a revival stem cell.	CLU YAP1	6.13e-05	6	71	2	31019301
Pubmed	Tumor suppressor RBM5 directly interacts with the DExD/H-box protein DHX15 and stimulates its helicase activity.	DHX15 SNRNP200	6.13e-05	6	71	2	22569250
Pubmed	Coordinated hedgehog signaling induces new hair follicles in adult skin.	KRT5 PTCH1	6.13e-05	6	71	2	32178760
Pubmed	A 'toothache tree' alkylamide inhibits Aδ mechanonociceptors to alleviate mechanical pain.	SCN8A SCN9A	6.13e-05	6	71	2	23652591
Pubmed	YAP and TAZ are essential for basal and squamous cell carcinoma initiation.	YAP1 PTCH1	8.57e-05	7	71	2	29875149
Pubmed	Neuropilins are positive regulators of Hedgehog signal transduction.	PTCH1 NRP1	8.57e-05	7	71	2	22051878
Pubmed	Mitochondrial reactive oxygen species modulate innate immune response to influenza A virus in human nasal epithelium.	IL10RB IFNAR1	8.57e-05	7	71	2	25930096
Pubmed	Interactions between the evolutionarily conserved, actin-related protein, Arp11, actin, and Arp1.	ACTR1B ACTR1A	8.57e-05	7	71	2	12857853
Pubmed	MOBKL1A/MOBKL1B phosphorylation by MST1 and MST2 inhibits cell proliferation.	MOB1B MOB1A	8.57e-05	7	71	2	18328708
Pubmed	Neddylation mediates ventricular chamber maturation through repression of Hippo signaling.	YAP1 MOB1B MOB1A	8.84e-05	42	71	3	29632206
Pubmed	Molecular characterization of human homologs of yeast MOB1.	MOB1B MOB1A	1.14e-04	8	71	2	19739119
Pubmed	SPATA2 Links CYLD to LUBAC, Activates CYLD, and Controls LUBAC Signaling.	DHX15 ACTR1B ACTR1A KRT5 KRT84 MOB1B RCN2	1.44e-04	558	71	7	27591049
Pubmed	International Union of Pharmacology. XLVII. Nomenclature and structure-function relationships of voltage-gated sodium channels.	SCN8A SCN9A	1.47e-04	9	71	2	16382098
Pubmed	The E3 Ubiquitin Ligase SYVN1 Ubiquitinates Atlastins to Remodel the Endoplasmic Reticulum Network.	SYVN1 ATL1	1.47e-04	9	71	2	32916628
Pubmed	Embryonic stem cell tumor model reveals role of vascular endothelial receptor tyrosine phosphatase in regulating Tie2 pathway in tumor angiogenesis.	KRT5 NEB	1.47e-04	9	71	2	20018779
Pubmed	T helper 1 effector memory CD4+ T cells protect the skin from poxvirus infection.	KRT5 IFNAR1	1.47e-04	9	71	2	37083328
Pubmed	Regulation of the Hippo-YAP pathway by G-protein-coupled receptor signaling.	YAP1 MOB1B	1.47e-04	9	71	2	22863277
Pubmed	Identification of candidate maternal-effect genes through comparison of multiple microarray data sets.	ZNF18 EHF NRP1	1.77e-04	53	71	3	16964442
Pubmed	Evc regulates a symmetrical response to Shh signaling in molar development.	EVC PTCH1	1.83e-04	10	71	2	23315474
Pubmed	Hedgehog regulates distinct vascular patterning events through VEGF-dependent and -independent mechanisms.	PTCH1 NRP1	1.83e-04	10	71	2	20339091
Pubmed	Inactivation of Lats1 and Lats2 highlights the role of hippo pathway effector YAP in larynx and vocal fold epithelium morphogenesis.	KRT5 YAP1	2.23e-04	11	71	2	33515576
Pubmed	The Hippo pathway effector YAP is an essential regulator of ductal progenitor patterning in the mouse submandibular gland.	KRT5 YAP1	2.23e-04	11	71	2	28492365
Pubmed	Soluble VEGF isoforms are essential for establishing epiphyseal vascularization and regulating chondrocyte development and survival.	PTCH1 NRP1	2.23e-04	11	71	2	14722611
Pubmed	The IFT-A complex regulates Shh signaling through cilia structure and membrane protein trafficking.	IFT122 PTCH1	2.23e-04	11	71	2	22689656
Pubmed	Ligand binding to WW tandem domains of YAP2 transcriptional regulator is under negative cooperativity.	YAP1 PTCH1	2.23e-04	11	71	2	25283809
Pubmed	Interaction proteome of human Hippo signaling: modular control of the co-activator YAP1.	DHX15 YAP1 MOB1B MOB1A RCN2	2.33e-04	270	71	5	24366813
Pubmed	Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche.	OLFM3 PTPRN2 MCHR2 ALOX15B	2.52e-04	149	71	4	25231870
Pubmed	Yes-associated protein (YAP) transcriptional coactivator functions in balancing growth and differentiation in skin.	KRT5 YAP1	2.68e-04	12	71	2	21262812
Pubmed	The Hippo pathway kinases LATS1 and LATS2 attenuate cellular responses to heavy metals through phosphorylating MTF1.	YAP1 MOB1A	2.68e-04	12	71	2	35027733
Pubmed	Evc is a positive mediator of Ihh-regulated bone growth that localises at the base of chondrocyte cilia.	EVC PTCH1	2.68e-04	12	71	2	17660199
Pubmed	Mechanochemical control of epidermal stem cell divisions by B-plexins.	YAP1 PTCH1	3.16e-04	13	71	2	33637728
Pubmed	Role of epidermal primary cilia in the homeostasis of skin and hair follicles.	KRT5 PTCH1	3.16e-04	13	71	2	21429982
Pubmed	Excess NF-κB induces ectopic odontogenesis in embryonic incisor epithelium.	KRT5 PTCH1	3.16e-04	13	71	2	25376721
Pubmed	Regulation of neuronal voltage-gated sodium channels by the ubiquitin-protein ligases Nedd4 and Nedd4-2.	SCN8A SCN9A	3.16e-04	13	71	2	15123669
Pubmed	The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.	DHX15 TTLL12 ACTR1A USP24 MOB1A RCN2 SNRNP200	3.26e-04	638	71	7	33239621
Pubmed	Mice with a targeted mutation of patched2 are viable but develop alopecia and epidermal hyperplasia.	KRT5 PTCH1	3.68e-04	14	71	2	16914743
Pubmed	Deubiquitylase USP9X suppresses tumorigenesis by stabilizing large tumor suppressor kinase 2 (LATS2) in the Hippo pathway.	YAP1 MOB1A	3.68e-04	14	71	2	29183995
Pubmed	The chromatin remodeler Mi-2beta is required for establishment of the basal epidermis and normal differentiation of its progeny.	KRT5 PTCH1	3.68e-04	14	71	2	17360773
Pubmed	Complex interactions between genes controlling trafficking in primary cilia.	IFT122 PTCH1	3.68e-04	14	71	2	21552265
Pubmed	The cellular EJC interactome reveals higher-order mRNP structure and an EJC-SR protein nexus.	DHX15 DOCK4 KRT5 SNRNP200	4.06e-04	169	71	4	23084401
Pubmed	Multisite dependency of an E3 ligase controls monoubiquitylation-dependent cell fate decisions.	PI4KA KBTBD8	4.24e-04	15	71	2	29999490
Pubmed	Adult interfollicular tumour-initiating cells are reprogrammed into an embryonic hair follicle progenitor-like fate during basal cell carcinoma initiation.	KRT5 PTCH1	4.24e-04	15	71	2	23178882
Pubmed	Meta-analyses of genome-wide association studies identify multiple loci associated with pulmonary function.	PTCH1 PID1	4.84e-04	16	71	2	20010835
Pubmed	Hague (Hag). A new mouse hair mutation with an unstable semidominant allele.	KRT5 KRT84	4.84e-04	16	71	2	12399393
Pubmed	A new role for FBP21 as regulator of Brr2 helicase activity.	DHX15 SNRNP200	4.84e-04	16	71	2	28838205
Pubmed	The ciliary Evc/Evc2 complex interacts with Smo and controls Hedgehog pathway activity in chondrocytes by regulating Sufu/Gli3 dissociation and Gli3 trafficking in primary cilia.	EVC PTCH1	4.84e-04	16	71	2	23026747
Pubmed	Hedgehog-Activated Fat4 and PCP Pathways Mediate Mesenchymal Cell Clustering and Villus Formation in Gut Development.	YAP1 PTCH1	5.48e-04	17	71	2	32155439
Pubmed	Yap controls notochord formation and neural tube patterning by integrating mechanotransduction with FoxA2 and Shh expression.	YAP1 PTCH1	5.48e-04	17	71	2	37315133
Pubmed	The formation of endoderm-derived taste sensory organs requires a Pax9-dependent expansion of embryonic taste bud progenitor cells.	KRT5 PTCH1	5.48e-04	17	71	2	25299669
Pubmed	The necdin interactome: evaluating the effects of amino acid substitutions and cell stress using proximity-dependent biotinylation (BioID) and mass spectrometry.	DHX15 TTLL12 ACTR1A KRT5 SNRNP200	5.82e-04	330	71	5	32529326
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	DHX15 TTLL12 ACTR1A GTF3C1 PI4KA RCN2 CMYA5 PLEKHA7 SNRNP200 ADGRA3	6.13e-04	1425	71	10	30948266
Pubmed	Defective ciliogenesis, embryonic lethality and severe impairment of the Sonic Hedgehog pathway caused by inactivation of the mouse complex A intraflagellar transport gene Ift122/Wdr10, partially overlapping with the DNA repair gene Med1/Mbd4.	IFT122 PTCH1	6.16e-04	18	71	2	19000668
Pubmed	Ciliary Hedgehog signaling patterns the digestive system to generate mechanical forces driving elongation.	YAP1 PTCH1	6.16e-04	18	71	2	34893605
Pubmed	Epithelial Expression of YAP and TAZ Is Sequentially Required in Lung Development.	YAP1 PTCH1	6.87e-04	19	71	2	31486675
Pubmed	Patched 1 and patched 2 redundancy has a key role in regulating epidermal differentiation.	KRT5 PTCH1	6.87e-04	19	71	2	24492243
Pubmed	The hippo pathway effector Yap controls patterning and differentiation of airway epithelial progenitors.	KRT5 YAP1	6.87e-04	19	71	2	25043473
Pubmed	Multiple roles for HOXA3 in regulating thymus and parathyroid differentiation and morphogenesis in mouse.	KRT5 PTCH1	6.87e-04	19	71	2	25249461
Pubmed	Crumbs3-Mediated Polarity Directs Airway Epithelial Cell Fate through the Hippo Pathway Effector Yap.	KRT5 YAP1	6.87e-04	19	71	2	26235047
Pubmed	A microRNA-Hippo pathway that promotes cardiomyocyte proliferation and cardiac regeneration in mice.	YAP1 MOB1B	6.87e-04	19	71	2	25787764
Pubmed	Ski regulates Hippo and TAZ signaling to suppress breast cancer progression.	YAP1 MOB1B MOB1A	6.90e-04	84	71	3	25670202
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	TTLL12 GTF3C1 PTPRN2 PI4KA SCN8A SNRNP200 OMG	7.60e-04	736	71	7	29676528
GeneFamily	MOB kinase activators\|STRIPAK complex	MOB1B MOB1A	1.15e-04	7	43	2	647
GeneFamily	Sodium voltage-gated channel alpha subunits	SCN8A SCN9A	1.97e-04	9	43	2	1203
GeneFamily	Keratins, type II	KRT5 KRT84	1.87e-03	27	43	2	609
GeneFamily	CD molecules\|I-set domain containing\|Immunoglobulin like domain containing\|Interleukin receptors\|TIR domain containing	IL10RB IL13RA2	4.48e-03	42	43	2	602
ToppCell	COPD-Epithelial-Basal\|COPD / Disease state, Lineage and Cell class	KRT5 CLU YAP1 EHF ADGRA3 PPL	4.80e-07	183	71	6	0f760e393edc91009bf6c7e02eeac039a1dfb4ed
ToppCell	Tracheal-10x3prime_v2-Epithelial-Epi_airway_neuro-secretory\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	OLFM3 DSCAM SCN8A SCN9A SRPK3 NEB	7.38e-07	197	71	6	ff4df77117165b6b25315e29b0722cc136eba607
ToppCell	5'-Adult-Distal_Rectal-Hematopoietic\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	EDEM3 SCN8A SCN9A ZNF214 NEB	8.41e-06	173	71	5	b335ca2a247156eba821943b2b9fc9922230b409
ToppCell	3'_v3-blood-Myeloid_Dendritic-pDC\|blood / Manually curated celltypes from each tissue	KRT5 MOB1B SCN9A SRPK3 NRP1	1.05e-05	181	71	5	66d890a105f955dca91d6e5e6c730d1a68ee9233
ToppCell	COPD-Epithelial-Basal\|World / Disease state, Lineage and Cell class	KRT5 YAP1 EHF ADGRA3 PPL	1.05e-05	181	71	5	6d8a886b4afe729f8a05b9c0f4ea9375de735da4
ToppCell	Control-Epithelial-Basal\|World / Disease state, Lineage and Cell class	KRT5 CLU YAP1 EHF PPL	1.08e-05	182	71	5	759390dde9b18757f7675d13d44c89d0e32f8d93
ToppCell	Control-Epithelial-Basal\|Control / Disease state, Lineage and Cell class	KRT5 CLU YAP1 EHF PPL	1.08e-05	182	71	5	caddd0a52f0234ea6a916186ffaf2454cdcd80ee
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SLC9C1 YAP1 EHF PID1 ALOX15B	1.10e-05	183	71	5	6847c1252d6bb105524f812658112517fd351eab
ToppCell	facs-Pancreas-Endocrine-3m-Epithelial-pancreatic_D_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OLFM3 DSCAM CLU EHF SCN9A	1.29e-05	189	71	5	fcc3713e8200d51074f709f3360fb36efb0a639f
ToppCell	10x5'-Liver-Myeloid_Dendritic\|Liver / Manually curated celltypes from each tissue	KRT5 ENOX1 EHF SCN9A PID1	1.46e-05	194	71	5	e6391bc7073831847c469ef0b0c437118e1f151f
ToppCell	10x5'-bone_marrow-Myeloid_Dendritic\|bone_marrow / Manually curated celltypes from each tissue	KRT5 ENOX1 EHF SCN9A NRP1	1.46e-05	194	71	5	768271ae45ff9f6aa3cd9b0ed15fa3caaa68a7b0
ToppCell	10x5'-lymph-node_spleen-Myeloid_Dendritic\|lymph-node_spleen / Manually curated celltypes from each tissue	KRT5 ENOX1 EHF SCN9A PID1	1.46e-05	194	71	5	e2d9186a7e8d1a4a71d7bd6dba7fc955d55479e6
ToppCell	wk_20-22-Epithelial-Proximal_epithelial-Club\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	CLU EHF GKN2 PLEKHA7 PPL	1.54e-05	196	71	5	4e4c632db73b1340d80bf40a7657cb4821084d3c
ToppCell	mLN-(5)_Dendritic_cell\|mLN / shred on region, Cell_type, and subtype	KRT5 ENOX1 EHF SCN9A NRP1	1.65e-05	199	71	5	4feecf533e29a1a558f1018a2e8f7bfa7b9d3864
ToppCell	mLN-Dendritic_cell\|mLN / Region, Cell class and subclass	KRT5 ENOX1 EHF SCN9A NRP1	1.65e-05	199	71	5	597412beae1324b9c43ca2bb96c4cb645c19f3e9
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Pvalb-Pvalb_Reln_Itm2a\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	PMIS2 SCN9A ZNF804A ADGRA3	8.28e-05	144	71	4	0bbe670454846cf9bc7464ae4e91488415c4111d
ToppCell	Basal_cells-Donor_02\|World / lung cells shred on cell class, cell subclass, sample id	KRT5 CLU EHF CMYA5	1.02e-04	152	71	4	72499e4d2b374ef5f1621c89d94727ecf4bd4d5d
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_PP_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MOB1B NAP1L2 CMYA5 ALOX15B	1.07e-04	154	71	4	2d98bb7a784fc3215e0d4a1670d662e5df4716c3
ToppCell	Ionocyte\|World / shred by cell class for nasal brushing	DHX15 OLFM3 SCN9A SRPK3	1.07e-04	154	71	4	6b78fb0c96fc7b5e901c39b3424f4aa8d0a6b9cf
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_PP_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MOB1B NAP1L2 CMYA5 ALOX15B	1.07e-04	154	71	4	0dec222101530f1727184dbb7c03969d3884f111
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW19-Mesenchymal\|GW19 / Sample Type, Dataset, Time_group, and Cell type.	ADAMTS12 OLFM3 SCN9A NMRK1	1.21e-04	159	71	4	f34f2729a3872fbb2939e76ad35d7e25f71b8f57
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW19-Mesenchymal-Unfolded_protein_responsible_cell\|GW19 / Sample Type, Dataset, Time_group, and Cell type.	ADAMTS12 OLFM3 SCN9A NMRK1	1.21e-04	159	71	4	929ed98f6c2ad14e8d5af5c6f11a5a3d4b388cf7
ToppCell	droplet-Lung-18m-Hematologic-lymphocytic-plasma_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	EDEM3 SCN8A SYVN1 PPL	1.37e-04	164	71	4	b92e7c91910d518627376166c6ea9ed333b3d07e
ToppCell	droplet-Lung-18m-Hematologic-lymphocytic-plasma_cell-plasma_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	EDEM3 SCN8A SYVN1 PPL	1.37e-04	164	71	4	a1e43c6b3e2553f5604100db6e92bf244b70c36d
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Pvalb-Pvalb_Reln_Tac1\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	DOCK4 SCN9A ZNF804A ADGRA3	1.40e-04	165	71	4	d8df50f5a3b646e8ea13739fdc65ce6f39b4d4d2
ToppCell	Mild-Myeloid-Mast\|Mild / Condition, Lineage, Cell class and cell subclass	PDE6A CLU SCN9A MINAR1	1.40e-04	165	71	4	5fa9552c37890c5cc7e672a47038aebba2413cb4
ToppCell	Mild-Myeloid-Mast-\|Mild / Condition, Lineage, Cell class and cell subclass	PDE6A CLU SCN9A MINAR1	1.40e-04	165	71	4	93d3909a0f5f43d473d5005c842d7d73e25eceed
ToppCell	facs-Marrow-B-cells-24m-Myeloid-granulocyte_monocyte_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTS12 DSCAM KBTBD8 PTCH1	1.40e-04	165	71	4	6d315e0734079ad05336cc2c3f24d870c9105bc8
ToppCell	facs-Marrow-B-cells-24m-Myeloid-granulocyte_monocyte_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTS12 DSCAM KBTBD8 PTCH1	1.40e-04	165	71	4	84f5597b1bb75f42de9a224196bb8ac198bbe3bf
ToppCell	367C-Fibroblasts-Fibroblast-G\|367C / Donor, Lineage, Cell class and subclass (all cells)	DOCK4 IL13RA2 CMYA5 PTCH1	1.50e-04	168	71	4	8c95093b1ea45826f62893edd3c410fe53b563a4
ToppCell	control-Myeloid-pDC\|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	KRT5 SCN9A ZNF529 NRP1	1.50e-04	168	71	4	affc39c7568b7df4b36af6f5b0e3702a18b6268c
ToppCell	367C-Fibroblasts-Fibroblast-G-\|367C / Donor, Lineage, Cell class and subclass (all cells)	DOCK4 IL13RA2 CMYA5 PTCH1	1.50e-04	168	71	4	b8c65542a0701ae31f49d332d87a64578e24b4e3
ToppCell	ICU-SEP-Myeloid-pDC\|ICU-SEP / Disease, Lineage and Cell Type	KRT5 SCN9A MINAR1 NRP1	1.60e-04	171	71	4	72c448a0dc4c569bd6b465f9aa395f38034e7ea6
ToppCell	mild_COVID-19-pDC\|World / disease group, cell group and cell class (v2)	KRT5 ENOX1 SCN9A NRP1	1.64e-04	172	71	4	dab2f1a05c7df58d9387b13271b3f1f1583f9ac3
ToppCell	mild_COVID-19-pDC\|mild_COVID-19 / disease group, cell group and cell class (v2)	KRT5 ENOX1 SCN9A NRP1	1.75e-04	175	71	4	b87f279a7519710146c49d6acccb0adedc195965
ToppCell	normal_Lymph_Node-B_lymphocytes-GrB-secreting_B_cells\|B_lymphocytes / Location, Cell class and cell subclass	KRT5 SCN9A ADGRA3 NRP1	1.79e-04	176	71	4	d6e660df92a3d7dd5732171ee623763faf108476
ToppCell	Healthy/Control-pDC\|Healthy/Control / Disease group and Cell class	KRT5 SCN9A ADGRA3 NRP1	1.87e-04	178	71	4	072b346c6bbd63f00efaceda486400a669b3ec48
ToppCell	droplet-Liver-LIVER_HEP-30m-Lymphocytic-B_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ENOX1 PTPRN2 SCN9A CMYA5	1.87e-04	178	71	4	d3cbdec9d75f076e565baca05ede292cca7758a4
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTS12 PTCH1 PID1 NRP1	1.87e-04	178	71	4	78a0c6340001a77f5b2d890b6263f574af2e72da
ToppCell	renal_papilla_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	SLC9C1 CLU EHF PPL	1.95e-04	180	71	4	49829e833fe6d2431cfd2e8f378c2aaa3b2b46a4
ToppCell	ICU-NoSEP-Myeloid-tDC\|ICU-NoSEP / Disease, Lineage and Cell Type	SCN9A ZNF804A PPL NRP1	1.95e-04	180	71	4	be665e801512f6aaf6b3ecb26153bbdeb24619ac
ToppCell	3'-GW_trimst-1-LargeIntestine-Neuronal-neurons_B-Branch_B2_(eMN)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	OLFM3 DSCAM SCN9A ATL1	1.95e-04	180	71	4	368ff7fcfd21ad248f96a83a8b191040ba7d8670
ToppCell	Healthy/Control-pDC\|World / Disease group and Cell class	KRT5 SCN9A ADGRA3 NRP1	2.04e-04	182	71	4	97e0eee10905f2cf2bebb09e474629fc224f4397
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTS12 RXFP2 PID1 NRP1	2.04e-04	182	71	4	44764676ed3f51ba171ce63f669390392fa50a43
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTS12 RXFP2 PID1 NRP1	2.04e-04	182	71	4	d82f59a3f930a840dde27dc6ab024f227a26d446
ToppCell	Control-Endothelial-Endothelial-Activated_Alv_Cap\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DOCK4 SCN9A NRP1 IFNAR1	2.08e-04	183	71	4	e81c142770f44fd902b0631bc360c5b5339d4c75
ToppCell	COPD-Epithelial-Club\|World / Disease state, Lineage and Cell class	YAP1 EHF ADGRA3 PPL	2.21e-04	186	71	4	3006f4ab1eaf1eb34c10ca9f7c869603d2d25744
ToppCell	LAM-Lymphoid-pDC\|Lymphoid / Condition, Lineage and Cell class	KRT5 MOB1B SCN9A NRP1	2.26e-04	187	71	4	4d9ffd2bbdf1c9869e28991ce9331e4ccf3c0166
ToppCell	COPD-Epithelial-ATII\|COPD / Disease state, Lineage and Cell class	SLC9C1 YAP1 EHF GKN2	2.31e-04	188	71	4	eb6d79d733b53f64ca615bb777c64ed456866549
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTS12 PTCH1 PID1 NRP1	2.35e-04	189	71	4	c734e5693808a0333139e87bd5be2597a9252afe
ToppCell	IPF-Epithelial-Basal\|IPF / Disease state, Lineage and Cell class	KRT5 YAP1 EHF PPL	2.40e-04	190	71	4	ea19e9ce954f2dfde97388db9695325cd92ab88f
ToppCell	droplet-Tongue-nan-3m-Epithelial-filiform\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL13RA2 CLU KRT84 NRP1	2.40e-04	190	71	4	251e3a33041023bfc4b547c7eb68cfb8f421636f
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTS12 PTCH1 PID1 NRP1	2.40e-04	190	71	4	2e592323085ba9c019d678ac2a784462ab470ed9
ToppCell	(5)_Fibroblasts-(5)_Fibroblast-C_(Myofibroblast)\|(5)_Fibroblasts / Lung cell shreds - cell class (v4) and cell subclass (v4)	ADAMTS12 DOCK4 IL13RA2 OMG	2.40e-04	190	71	4	71e112dfb8c3190fe0286b45a046ea789eb6a8db
ToppCell	PCW_13-14\|World / Celltypes from embryonic and fetal-stage human lung	ADAMTS12 DOCK4 YAP1 NRP1	2.40e-04	190	71	4	62a3ec1ae0829602b0569cc051210551644f1d46
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTS12 PTCH1 PID1 NRP1	2.40e-04	190	71	4	445952b70abffadb6ccc1ed4bbf61a88b06b73b3
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CLU MOB1B EHF CMYA5	2.40e-04	190	71	4	078f4be52fa4cc8dd9c8d7a2b6d9631c3d902285
ToppCell	3'_v3-lymph-node_spleen-Myeloid_Dendritic\|lymph-node_spleen / Manually curated celltypes from each tissue	KRT5 ENOX1 SCN9A NRP1	2.45e-04	191	71	4	c3ff4342e0eea1e1f071b1fbca14a6dd4df0c696
ToppCell	COPD-Epithelial-Club\|COPD / Disease state, Lineage and Cell class	YAP1 EHF ADGRA3 PPL	2.45e-04	191	71	4	c909cf5fa0e6519aa93a47d2c3fcd2ae2163cd8d
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2\|Children_(3_yrs) / Lineage, Cell type, age group and donor	YAP1 EHF PID1 ALOX15B	2.45e-04	191	71	4	a0332a4ef629510fb313ec119195c44a3f704a80
ToppCell	COVID-19-lung-AT2\|lung / Disease (COVID-19 only), tissue and cell type	EHF PLEKHA7 PID1 ALOX15B	2.45e-04	191	71	4	276455a64c2c3503d5048615762eb2ee37f0ac70
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTS12 PTCH1 PID1 NRP1	2.45e-04	191	71	4	806b94f567ea09a9f443cd4091e70cdb1253ac08
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro1_(4)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	ADAMTS12 ENOX1 PID1 NRP1	2.45e-04	191	71	4	fa380a8752de158974b2ae5e741573439719cc0d
ToppCell	Entopeduncular-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	OLFM3 PTPRN2 NAP1L2 ZNF804A	2.45e-04	191	71	4	5d24022cec293bc8d9e978ae99a109e660bb8f83
ToppCell	Entopeduncular-Neuronal-Inhibitory\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	OLFM3 PTPRN2 NAP1L2 ZNF804A	2.45e-04	191	71	4	73dae4cdea86aec62393ad7303dc7375a6b3fc86
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTS12 PTCH1 PID1 NRP1	2.50e-04	192	71	4	bc84b9ce01b4d826a682842ab8a395dac9b91183
ToppCell	Epithelial-alveolar_epithelial_cell_type_2\|World / Lineage, Cell type, age group and donor	YAP1 EHF PID1 ALOX15B	2.50e-04	192	71	4	58c3737be7acce39fd2b91d70d6d7b2bbaa4f710
ToppCell	wk_08-11-Epithelial-PNS-KCNIP4+_neuron\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	OLFM3 DSCAM MCHR2 ZNF804A	2.50e-04	192	71	4	53642c88891f4e4e14b1740c5ced759b7d8b3572
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2-D122\|Adult / Lineage, Cell type, age group and donor	YAP1 EHF PID1 ALOX15B	2.50e-04	192	71	4	06013a07e3a873b1d1c0451643c528593ac32a9c
ToppCell	IPF-Epithelial-Basal\|World / Disease state, Lineage and Cell class	KRT5 YAP1 EHF PPL	2.50e-04	192	71	4	9b91e0b162e6f3ce86dd15cc33c2e745d069581f
ToppCell	Smart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-AC-like-AC-like_Prolif-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	EVC SRPK3 PTCH1 ADGRA3	2.50e-04	192	71	4	d6f656be2698bd215717d35f4e7ab727c08c61e0
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTS12 PTCH1 PID1 NRP1	2.50e-04	192	71	4	0ab1176cfbb0de8dd1f22c6e2c41265cf6c10ee1
ToppCell	droplet-Pancreas-Endocrine-18m-Epithelial-pancreatic_D_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OLFM3 DSCAM EHF RCN2	2.55e-04	193	71	4	6995ee29bf403a71247de92a37dfd851be5acf2e
ToppCell	ASK440-Epithelial-Secretory\|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq	KRT5 CLU EHF PPL	2.55e-04	193	71	4	50e98d91697c7af6a3de39e52edde6dd2b67b512
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2\|Adult / Lineage, Cell type, age group and donor	YAP1 EHF PID1 ALOX15B	2.55e-04	193	71	4	738f4f0a9ddde2432b429ab46838e353b1790589
ToppCell	droplet-Pancreas-Endocrine-18m-Epithelial-pancreatic_D_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OLFM3 DSCAM EHF RCN2	2.55e-04	193	71	4	7fcfb0f76789fa8d8caa18304cb43c8fd899a81b
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ADAMTS12 DOCK4 ENOX1 NRP1	2.60e-04	194	71	4	011e14d9ed1393275f892060e7708ffadcd0767f
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	EVC PLEKHA7 ADGRA3 PPL	2.60e-04	194	71	4	e577d9e88390b36b5a09b97fe1026089892275a3
ToppCell	Hippocampus-Neuronal\|Hippocampus / BrainAtlas - Mouse McCarroll V32	ACTR1B PTPRN2 SCN8A NAP1L2	2.60e-04	194	71	4	8aeb347b3024354c9505f4f0fddf0b843489dc6b
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTS12 PTCH1 PID1 NRP1	2.60e-04	194	71	4	e03ba6caed59fa64d4d9b042593469d4a6a3dc10
ToppCell	AT2_cells-Donor_01\|World / lung cells shred on cell class, cell subclass, sample id	EHF GKN2 PID1 ALOX15B	2.65e-04	195	71	4	0792c1e959e933b10ae987d821ff43020dfdabad
ToppCell	cellseq-Epithelial-Epithelial_Alveolar-AT2-AT2\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	YAP1 GKN2 PID1 ALOX15B	2.65e-04	195	71	4	6867f9c56ea27a17c8c4099aae0d79903c3748a5
ToppCell	cellseq-Epithelial-Epithelial_Alveolar-AT2\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	YAP1 GKN2 PID1 ALOX15B	2.65e-04	195	71	4	955a0a7244cd7eaf006a39e1bd03333baf6f30a4
ToppCell	Control-Epithelial\|Control / Disease state, Lineage and Cell class	SLC9C1 YAP1 EHF GKN2	2.65e-04	195	71	4	1798c3b89b1b5ff4f5777d2b9f52dc81cdad28fa
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SLC9C1 EHF PLEKHA7 PPL	2.70e-04	196	71	4	c7136b1c83bcf907eec3b02b151fa061298b6672
ToppCell	ASK440-Epithelial-Type_2\|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq	YAP1 GKN2 PID1 ALOX15B	2.70e-04	196	71	4	754b4202b617165c6994a0b5a9b1e486dccdd44d
ToppCell	367C-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	SCN9A PID1 NRP1 TPCN1	2.70e-04	196	71	4	e8c4eeb4b6c6d9bccca2adb942d4cfbaab39636c
ToppCell	Tracheal-NucSeq-Stromal-Pericyte-Muscle_pericyte_pulmonary\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ADAMTS12 TSNAXIP1 TMEM147 SCN9A	2.75e-04	197	71	4	06e17c9ad53463eee1007280b3f3e8b0cf446cdc
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CLU YAP1 EHF PLEKHA7	2.75e-04	197	71	4	7e93a97b5ac5ae2f77a4b3141082a1463fed00dd
ToppCell	Monocytes-NUPR1+_Monocytes\|Monocytes / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	DOCK4 CLU SNRNP200 TPCN1	2.75e-04	197	71	4	8a058c9d9285acd7cf2fb8e34f7602a86b5d6c89
ToppCell	Transverse-(5)_Dendritic_cell-(53)_Lymphoid_DC\|Transverse / shred on region, Cell_type, and subtype	ENOX1 MOB1B NEB PLEKHA7	2.75e-04	197	71	4	15b87fd3906d7388c271d30d0c64b1bcc490801c
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature1_(0)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	ADAMTS12 ENOX1 YAP1 PID1	2.75e-04	197	71	4	0034bae02ee7fcfea520d453ca3c842ab6963b12
ToppCell	IPF-Stromal-Myofibroblast\|Stromal / Disease state, Lineage and Cell class	ADAMTS12 DOCK4 YAP1 NRP1	2.75e-04	197	71	4	f304d42fc4936fe20996e07c8dccc698a6e5e5ef
ToppCell	Transverse-Dendritic_cell-Lymphoid_DC\|Transverse / Region, Cell class and subclass	ENOX1 MOB1B NEB PLEKHA7	2.75e-04	197	71	4	a58af0ea82f76f2a7abac1f62629ff20d552fc63
ToppCell	Bronchus_Control_(B.)-Epithelial-TX-Basal_1\|Bronchus_Control_(B.) / Sample group, Lineage and Cell type	KRT5 OLFM3 ZNF212 SCN9A	2.81e-04	198	71	4	f632342e1e8911dd82b5df171776a84c7dc3f931
ToppCell	Tracheal-10x3prime_v2-Epithelial-Epi_airway_neuro-secretory-Ionocyte_n_Brush\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	OLFM3 DSCAM SCN9A SRPK3	2.81e-04	198	71	4	62059185afdf66126a6fbc899ce611c47e7a0feb
ToppCell	distal-1-Epithelial-Alveolar_Epithelial_Type_2\|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	YAP1 GKN2 PID1 ALOX15B	2.81e-04	198	71	4	ce9d6b2a93c7b304414ce1b8b1a09562cf581278
ToppCell	Bronchial-NucSeq-Epithelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SLC9C1 YAP1 EHF PLEKHA7	2.86e-04	199	71	4	5f7da3eab58ace6cddb3179a415cd839d5767958
ToppCell	Fetal_29-31_weeks\|World / Lineage, Cell type, age group and donor	ADAMTS12 ENOX1 YAP1 ADGRA3	2.86e-04	199	71	4	5b9d355795dd03a22f0961dfd143425c367a4654
ToppCell	distal-1-Epithelial\|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	YAP1 EHF GKN2 ALOX15B	2.86e-04	199	71	4	9086dbb60863c3da2cc5d0a310f28596a01c52ca
Disease	B Virus Infection	SCN8A SCN9A	1.66e-05	3	70	2	C0037140
Disease	Postherpetic neuralgia	SCN8A SCN9A	1.66e-05	3	70	2	C0032768
Disease	Herpesviridae Infections	SCN8A SCN9A	1.66e-05	3	70	2	C0019372
Disease	Sensory Neuropathy, Hereditary	SCN9A ATL1	8.27e-05	6	70	2	C0699739
Disease	Alzheimer disease, peptic ulcer disease	DSCAM CLU RCN2	1.10e-04	39	70	3	MONDO_0004247, MONDO_0004975
Disease	Myopathies, Nemaline	SRPK3 NEB	1.54e-04	8	70	2	C0206157
Disease	molar-incisor hypomineralization	DHX15 TTLL12	1.98e-04	9	70	2	EFO_0005321
Disease	interferon alpha/beta receptor 1 measurement	IL10RB IFNAR1	1.98e-04	9	70	2	EFO_0021850
Disease	generalized epilepsy with febrile seizures plus 2 (implicated_via_orthology)	SCN8A SCN9A	2.47e-04	10	70	2	DOID:0111294 (implicated_via_orthology)
Disease	Dravet syndrome (implicated_via_orthology)	SCN8A SCN9A	2.47e-04	10	70	2	DOID:0080422 (implicated_via_orthology)
Disease	generalized epilepsy with febrile seizures plus (implicated_via_orthology)	SCN8A SCN9A	3.61e-04	12	70	2	DOID:0060170 (implicated_via_orthology)
Disease	Schizoaffective disorder-bipolar type	PTCH1 ZNF804A	6.52e-04	16	70	2	EFO_0009965
Disease	Retinitis pigmentosa	PDE6A KLHL7 SNRNP200	7.35e-04	74	70	3	cv:C0035334
Disease	pulmonary non-tuberculous mycobacterial infection	CLU C3orf85	9.24e-04	19	70	2	MONDO_0018469
Disease	Disorder of eye	PDE6A KLHL7 MFSD8 SNRNP200	1.64e-03	212	70	4	C0015397
Disease	retinitis pigmentosa (implicated_via_orthology)	PDE6A SNRNP200	1.87e-03	27	70	2	DOID:10584 (implicated_via_orthology)
Disease	Retinitis Pigmentosa	PDE6A KLHL7 SNRNP200	1.96e-03	104	70	3	C0035334
Disease	Pigmented Basal Cell Carcinoma	KRT5 PTCH1	2.02e-03	28	70	2	C1368275
Disease	Carcinoma, Basal Cell	KRT5 PTCH1	2.16e-03	29	70	2	C4721806

Protein segments in the cluster

Peptide	Gene	Start	Entry
YWNNEYIMSLIEENS	PPP2R5E	366	Q16537
ASYIDQDMQVLWYQD	ADGRA3	266	Q8IWK6
MERIWQYVYSKDQLQ	ACTR1B	86	P42025
WIALKTTAQYYLDMN	C3orf85	66	A0A1B0GTC6
EWLVKIAPQYYDMSN	DHX15	756	O43143
SLQDYYWQISNTKQM	CC2D2B	361	Q6DHV5
YWQISNTKQMYDLER	CC2D2B	366	Q6DHV5
QSKYRVMNKDQWYNV	DCUN1D5	186	Q9BTE7
GLDNDVEQQMYFWQY	ADAMTS12	816	P58397
PETKVQDMDCVYYNW	IL13RA2	136	Q14627
TVTWDEYNIQMYDRV	RCN2	116	Q14257
DAIYDKIIYDNWMAA	NAP1L2	426	Q9ULW6
DMYAWTQEQAVLYNG	MFSD8	296	Q8NHS3
WQDDYTQYVMDQELA	PTPRN2	96	Q92932
DAEAWYQTKYEEMQV	KRT84	351	Q9NSB2
KDDIYMPYAQWLAEN	IFT122	861	Q9HBG6
EAESWYQTKYEELQQ	KRT5	356	P13647
LNYKAAYDNWNEQRM	KIAA1109	3286	Q2LD37
YMQWYNDELLQMAKQ	EDEM3	171	Q9BZQ6
LKWDYTYANMTFQVQ	IFNAR1	246	P17181
AWVYREINDDLSYQM	PID1	181	Q7Z2X4
QDYMQRCTNELYWLD	PPL	216	O60437
YESEQEWTQYMMLEQ	PDE6A	691	P16499
QFIWNMKTNIYLDEE	PI4KA	1686	P42356
DNVEYYDIKLNEWKM	KLHL7	496	Q8IXQ5
APKYIDYLMTWVQDQ	MOB1B	111	Q7L9L4
NSLYQYDDIADQWMK	KBTBD8	556	Q8NFY9
RYQKPEEYDQLVWMA	NRP1	741	O14786
LCYTWEMYQQNKDAR	MCHR2	221	Q969V1
NLQWYIYEKQALDNM	GKN2	96	Q86XP6
MYNQESVDWVGDYNE	ATL1	91	Q8WXF7
ILKVYMCNTESEWYQ	DOCK4	321	Q8N1I0
EPSIMNTWKDENYLY	EHF	136	Q9NZC4
YWSMNKEDVIDSFQV	CMYA5	3726	Q8N3K9
MERIWQYVYSKDQLQ	ACTR1A	86	P61163
IENEYETWTMKNVYN	IL10RB	136	Q08334
YSEQLIDNMEAFWKQ	EVC	306	P57679
NIEYLWSYMQQLDSK	ENOX1	586	Q8TC92
LASEKNNRVWYMDSY	OLFM3	246	Q96PB7
NNRVWYMDSYTNNKI	OLFM3	251	Q96PB7
LNPNNLEYWMEDIYT	MINAR1	856	Q9UPX6
ELQARQEMYQWKAYN	ALOX15B	141	O15296
YLKYRQEMQDITWEV	NMRK1	151	Q9NWW6
YDLQEATWYELQMRV	DSCAM	1536	O60469
SENPWDNKAVYMLYT	SYVN1	201	Q86TM6
QMYYRQQEDCAIWEA	SFI1	731	A8K8P3
REHLSYEDWNYNMQL	SLC9C1	1011	Q4G0N8
YEDWNYNMQLKLSNI	SLC9C1	1016	Q4G0N8
DYYQKWMEEQAQSLI	SNRPC	36	P09234
EMYENQAKYKDQWGQ	FER1L5	786	A0AVI2
APKYIDYLMTWVQDQ	MOB1A	111	Q9H8S9
MENAWNEYLKLENDV	PLEKHA7	771	Q6IQ23
INYQVDSWEEMLNKA	PTCH1	271	Q13635
RLMTQDYWENLYQQT	SCN9A	356	Q15858
QYQKYALLWMESVQC	RXFP2	481	Q8WXD0
MKANQNSEWEEAYIN	PMIS2	111	A0A1W2PS18
YQWNLKYLDVSKNML	OMG	121	P23515
YEVLMEKYEWPLEQA	SRPK3	521	Q9UPE1
YNELLKSYQWKMLNT	CLU	341	P10909
VARYWQQVIDMNDYQ	UGDH	296	O60701
WEQAMTQDGEIYYIN	YAP1	236	P46937
LMTQDYWENLYQLTL	SCN8A	366	Q9UQD0
VLEEMWKFNQTYQLA	TTLL12	166	Q14166
NWEMNYQEAAIYLQE	TPCN1	66	Q9ULQ1
AEQVYMDWYEKFQDR	SNRNP200	1386	O75643
MWNKELYVREQQDAY	USP24	1761	Q9UPU5
WQKELYRNVMESNYE	ZNF212	161	Q9UDV6
TQKEQYWDLMLETYG	ZNF18	231	P17022
RNLYWDVMMENYSNL	ZNF529	61	Q6P280
YVLNSMQDVENYWFD	GTF3C1	1026	Q12789
IEFDWKYIQMSIDSN	TMEM147	126	Q9BVK8
LWEQYMDEKDEYLQQ	TSNAXIP1	556	Q2TAA8
YTNVMSVENWNESYK	ZNF214	36	Q9UL59
EEMCKTWNTEYNTYD	ZNF804A	671	Q7Z570
ETMNKWNTFYQYLQS	LEG1	181	Q6P5S2
IQSDNVYKEDYNNWM	NEB	1186	P20929