Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionstructural constituent of nuclear pore

POM121 NUP155 POM121B

2.07e-0525433GO:0017056
GeneOntologyMolecularFunctionnuclear localization sequence binding

NOLC1 POM121 POM121B

2.62e-0527433GO:0008139
GeneOntologyMolecularFunctionstructural constituent of presynaptic active zone

BSN PCLO

1.26e-048432GO:0098882
GeneOntologyMolecularFunctionprotein-macromolecule adaptor activity

NOLC1 NRG1 ARID1B MED1 KMT2E MAP1A ABI2 CUX1 NACA BCORL1

1.39e-0411604310GO:0030674
GeneOntologyMolecularFunctionsignal sequence binding

NOLC1 POM121 POM121B

1.80e-0451433GO:0005048
GeneOntologyMolecularFunctionSH3 domain binding

CTTNBP2 REPS1 ABI2 DENND1A

2.51e-04143434GO:0017124
GeneOntologyMolecularFunctiongamma-catenin binding

APC APC2

2.95e-0412432GO:0045295
GeneOntologyMolecularFunctiongeneral transcription initiation factor binding

NOLC1 MED1 NACA

3.54e-0464433GO:0140296
GeneOntologyMolecularFunctionmolecular adaptor activity

NOLC1 NRG1 ARID1B MED1 KMT2E MAP1A ABI2 CUX1 NACA BCORL1

4.90e-0413564310GO:0060090
GeneOntologyMolecularFunctionmicrotubule plus-end binding

CKAP5 APC

1.02e-0322432GO:0051010
GeneOntologyMolecularFunctioncytoskeletal anchor activity

MAP1A ABI2

1.21e-0324432GO:0008093
GeneOntologyMolecularFunctiontranscription coregulator activity

NRG1 ARID1B MED1 KMT2E NACA BCORL1

1.22e-03562436GO:0003712
GeneOntologyMolecularFunctionhistone acetyltransferase binding

MED1 MEF2A

1.77e-0329432GO:0035035
GeneOntologyMolecularFunctionchemorepellent activity

NRG1 SEMA6A

1.77e-0329432GO:0045499
GeneOntologyMolecularFunctionbeta-catenin binding

APC SPECC1L APC2

2.19e-03120433GO:0008013
GeneOntologyMolecularFunctionprotein domain specific binding

NOLC1 CTTNBP2 REPS1 MED1 ZNF592 ABI2 DENND1A

2.46e-03875437GO:0019904
GeneOntologyMolecularFunctiontranscription coregulator binding

MED1 BSN PCLO

3.39e-03140433GO:0001221
GeneOntologyMolecularFunctionstructural constituent of synapse

BSN PCLO

3.69e-0342432GO:0098918
GeneOntologyMolecularFunctiontranscription coactivator activity

ARID1B MED1 KMT2E NACA

4.03e-03303434GO:0003713
GeneOntologyMolecularFunctionmicrotubule binding

CKAP5 APC MAP1A APC2

4.27e-03308434GO:0008017
GeneOntologyMolecularFunctiontranscription factor binding

NOLC1 MED1 BSN MEF2A PCLO NACA

5.23e-03753436GO:0008134
GeneOntologyMolecularFunctiontranscription corepressor binding

BSN PCLO

7.17e-0359432GO:0001222
GeneOntologyBiologicalProcessmicrotubule depolymerization

CKAP5 APC SPECC1L MAP1A APC2

2.52e-0766435GO:0007019
GeneOntologyBiologicalProcessnegative regulation of microtubule depolymerization

APC SPECC1L MAP1A APC2

1.15e-0638434GO:0007026
GeneOntologyBiologicalProcessregulation of microtubule depolymerization

APC SPECC1L MAP1A APC2

1.73e-0642434GO:0031114
GeneOntologyBiologicalProcessregulation of microtubule polymerization or depolymerization

CKAP5 APC SPECC1L MAP1A APC2

2.95e-06108435GO:0031110
GeneOntologyBiologicalProcessnegative regulation of microtubule polymerization or depolymerization

APC SPECC1L MAP1A APC2

3.81e-0651434GO:0031111
GeneOntologyBiologicalProcessprotein depolymerization

CKAP5 APC SPECC1L MAP1A APC2

1.20e-05144435GO:0051261
GeneOntologyBiologicalProcesspresynapse to nucleus signaling pathway

BSN PCLO

1.27e-053432GO:0099526
GeneOntologyBiologicalProcessmicrotubule polymerization or depolymerization

CKAP5 APC SPECC1L MAP1A APC2

2.53e-05168435GO:0031109
GeneOntologyBiologicalProcesspresynaptic signal transduction

BSN PCLO

2.54e-054432GO:0098928
GeneOntologyBiologicalProcessnucleus organization

NOLC1 POM121 NUP155 POM121B NECTIN2

2.68e-05170435GO:0006997
GeneOntologyBiologicalProcessprotein-containing complex disassembly

CKAP5 APC NRG1 SPECC1L MAP1A APC2

2.94e-05291436GO:0032984
GeneOntologyBiologicalProcessregulation of microtubule cytoskeleton organization

CKAP5 APC SPECC1L MAP1A APC2

3.16e-05176435GO:0070507
GeneOntologyBiologicalProcessnegative regulation of protein depolymerization

APC SPECC1L MAP1A APC2

3.51e-0589434GO:1901880
GeneOntologyBiologicalProcesspresynaptic active zone assembly

BSN PCLO

4.23e-055432GO:1904071
GeneOntologyBiologicalProcesscell-cell signaling involved in cardiac conduction

CACNA1G NUP155 RNF207

4.83e-0534433GO:0086019
GeneOntologyBiologicalProcessprotein import into nucleus

NOLC1 POM121 MED1 NUP155 POM121B

5.16e-05195435GO:0006606
GeneOntologyBiologicalProcessnegative regulation of protein-containing complex disassembly

APC SPECC1L MAP1A APC2

5.55e-05100434GO:0043242
GeneOntologyBiologicalProcesscardiac conduction

CACNA1G NUP155 RNF207 MEF2A

5.55e-05100434GO:0061337
GeneOntologyBiologicalProcessimport into nucleus

NOLC1 POM121 MED1 NUP155 POM121B

5.96e-05201435GO:0051170
GeneOntologyBiologicalProcessmaintenance of presynaptic active zone structure

BSN PCLO

6.33e-056432GO:0048790
GeneOntologyBiologicalProcessprotein localization to organelle

APC NOLC1 POM121 MED1 NUP155 MAP1A POM121B IQSEC2 NACA SEC16A

6.37e-0510914310GO:0033365
GeneOntologyBiologicalProcessregulation of protein depolymerization

APC SPECC1L MAP1A APC2

6.72e-05105434GO:1901879
GeneOntologyBiologicalProcessheart trabecula morphogenesis

NRG1 MED1 NACA

6.77e-0538433GO:0061384
GeneOntologyBiologicalProcessactin filament-based process

CACNA1G SPECC1L CTTNBP2 NUP155 ABI2 RNF207 MEF2A PCLO IQSEC2

9.02e-05912439GO:0030029
GeneOntologyBiologicalProcessprotein localization to synapse

BSN MAP1A PCLO IQSEC2

9.57e-05115434GO:0035418
GeneOntologyBiologicalProcesscell junction organization

CKAP5 APC NRG1 SPECC1L CTTNBP2 BSN ABI2 PCLO IQSEC2

1.49e-04974439GO:0034330
GeneOntologyBiologicalProcesssynaptic signaling

CKAP5 NRG1 CACNA1G ARID1B BSN MAP1A KCNQ4 PCLO IQSEC2

1.51e-04976439GO:0099536
GeneOntologyBiologicalProcesspresynaptic active zone organization

BSN PCLO

1.89e-0410432GO:1990709
GeneOntologyBiologicalProcessregulation of protein-containing complex disassembly

APC SPECC1L MAP1A APC2

2.28e-04144434GO:0043244
GeneOntologyBiologicalProcesstrabecula morphogenesis

NRG1 MED1 NACA

2.28e-0457433GO:0061383
GeneOntologyBiologicalProcessprotein localization to cell junction

BSN MAP1A PCLO IQSEC2

2.53e-04148434GO:1902414
GeneOntologyBiologicalProcesscell communication involved in cardiac conduction

CACNA1G NUP155 RNF207

2.53e-0459433GO:0086065
GeneOntologyBiologicalProcesscellular component disassembly

CKAP5 APC NRG1 SPECC1L MAP1A ABI2 APC2

2.62e-04617437GO:0022411
GeneOntologyBiologicalProcesspresynapse assembly

NRG1 BSN PCLO

2.66e-0460433GO:0099054
GeneOntologyBiologicalProcessregulation of supramolecular fiber organization

CKAP5 APC SPECC1L MAP1A ABI2 APC2

2.78e-04438436GO:1902903
GeneOntologyBiologicalProcesscardiac muscle cell action potential involved in contraction

CACNA1G NUP155 RNF207

2.93e-0462433GO:0086002
GeneOntologyBiologicalProcessregulation of microtubule-based process

CKAP5 APC SPECC1L MAP1A APC2

3.46e-04293435GO:0032886
GeneOntologyBiologicalProcesspresynapse organization

NRG1 BSN PCLO

4.74e-0473433GO:0099172
GeneOntologyBiologicalProcessRNA transport

CKAP5 POM121 NUP155 POM121B

4.77e-04175434GO:0050658
GeneOntologyBiologicalProcessnucleic acid transport

CKAP5 POM121 NUP155 POM121B

4.77e-04175434GO:0050657
GeneOntologyBiologicalProcesssynapse organization

CKAP5 NRG1 CTTNBP2 BSN ABI2 PCLO IQSEC2

4.91e-04685437GO:0050808
GeneOntologyBiologicalProcessestablishment of RNA localization

CKAP5 POM121 NUP155 POM121B

5.09e-04178434GO:0051236
GeneOntologyBiologicalProcessheart morphogenesis

APC NRG1 MED1 RNF207 NACA

5.25e-04321435GO:0003007
GeneOntologyBiologicalProcessventricular trabecula myocardium morphogenesis

NRG1 MED1

5.66e-0417432GO:0003222
GeneOntologyBiologicalProcesscardiac muscle tissue development

APC NRG1 CACNA1G MED1 MEF2A

5.70e-04327435GO:0048738
GeneOntologyBiologicalProcessanterograde trans-synaptic signaling

CKAP5 CACNA1G ARID1B BSN MAP1A KCNQ4 PCLO IQSEC2

5.94e-04931438GO:0098916
GeneOntologyBiologicalProcesschemical synaptic transmission

CKAP5 CACNA1G ARID1B BSN MAP1A KCNQ4 PCLO IQSEC2

5.94e-04931438GO:0007268
GeneOntologyBiologicalProcesstrans-synaptic signaling

CKAP5 CACNA1G ARID1B BSN MAP1A KCNQ4 PCLO IQSEC2

6.28e-04939438GO:0099537
GeneOntologyBiologicalProcessnuclear pore organization

POM121 POM121B

6.36e-0418432GO:0006999
GeneOntologyBiologicalProcessdendrite development

ARID1B MAP1A ABI2 MEF2A CUX1

6.36e-04335435GO:0016358
GeneOntologyBiologicalProcesscell morphogenesis

APC NRG1 SEMA6A MED1 MAP1A ABI2 MEF2A CDHR1 CUX1

6.69e-041194439GO:0000902
GeneOntologyBiologicalProcessnegative regulation of cytoskeleton organization

APC SPECC1L MAP1A APC2

7.03e-04194434GO:0051494
GeneOntologyBiologicalProcesspositive regulation of keratinocyte differentiation

MED1 ALOX15B

7.10e-0419432GO:0045618
GeneOntologyBiologicalProcessventricular cardiac muscle cell differentiation

NRG1 MEF2A

7.10e-0419432GO:0055012
GeneOntologyBiologicalProcessnegative regulation of supramolecular fiber organization

APC SPECC1L MAP1A APC2

7.44e-04197434GO:1902904
GeneOntologyBiologicalProcessstriated muscle tissue development

APC NRG1 CACNA1G MED1 MEF2A

7.65e-04349435GO:0014706
GeneOntologyBiologicalProcessintracellular protein transport

NOLC1 POM121 MED1 NUP155 MAP1A POM121B SEC16A

7.77e-04740437GO:0006886
GeneOntologyBiologicalProcesscardiac muscle cell action potential

CACNA1G NUP155 RNF207

7.92e-0487433GO:0086001
GeneOntologyBiologicalProcessintracellular transport

NOLC1 POM121 REPS1 MED1 BSN NUP155 MAP1A POM121B DENND1A SEC16A

8.21e-0414964310GO:0046907
GeneOntologyBiologicalProcesscell morphogenesis involved in neuron differentiation

APC SEMA6A MAP1A ABI2 MEF2A CDHR1 CUX1

8.28e-04748437GO:0048667
GeneOntologyBiologicalProcessneural crest cell development

NOLC1 NRG1 SEMA6A

8.46e-0489433GO:0014032
GeneOntologyBiologicalProcessheart development

APC NRG1 CACNA1G MED1 RNF207 MEF2A NACA

8.88e-04757437GO:0007507
GeneOntologyBiologicalProcessprotein localization to nucleus

NOLC1 POM121 MED1 NUP155 POM121B

9.02e-04362435GO:0034504
GeneOntologyBiologicalProcesssynaptic vesicle clustering

BSN PCLO

9.55e-0422432GO:0097091
GeneOntologyBiologicalProcesscardiac muscle cell contraction

CACNA1G NUP155 RNF207

9.61e-0493433GO:0086003
GeneOntologyBiologicalProcessmuscle tissue development

APC NRG1 CACNA1G MED1 MEF2A NACA

9.94e-04558436GO:0060537
GeneOntologyBiologicalProcessRNA export from nucleus

POM121 NUP155 POM121B

1.05e-0396433GO:0006405
GeneOntologyBiologicalProcessRNA localization

CKAP5 POM121 NUP155 POM121B

1.07e-03217434GO:0006403
GeneOntologyBiologicalProcessnuclear transport

NOLC1 POM121 MED1 NUP155 POM121B

1.09e-03378435GO:0051169
GeneOntologyBiologicalProcessnucleocytoplasmic transport

NOLC1 POM121 MED1 NUP155 POM121B

1.09e-03378435GO:0006913
GeneOntologyBiologicalProcesscell junction assembly

APC NRG1 BSN ABI2 PCLO IQSEC2

1.10e-03569436GO:0034329
GeneOntologyBiologicalProcessretrograde axonal transport

BSN MAP1A

1.14e-0324432GO:0008090
GeneOntologyBiologicalProcessregulation of cytoskeleton organization

CKAP5 APC SPECC1L MAP1A ABI2 APC2

1.20e-03579436GO:0051493
GeneOntologyBiologicalProcessstem cell development

NOLC1 NRG1 SEMA6A

1.22e-03101433GO:0048864
GeneOntologyBiologicalProcesscellular component maintenance

CKAP5 BSN PCLO

1.22e-03101433GO:0043954
GeneOntologyBiologicalProcessactivation of protein kinase B activity

NRG1 DYNAP

1.24e-0325432GO:0032148
GeneOntologyBiologicalProcessneural crest cell differentiation

NOLC1 NRG1 SEMA6A

1.33e-03104433GO:0014033
GeneOntologyBiologicalProcessperoxisome proliferator activated receptor signaling pathway

MED1 ALOX15B

1.55e-0328432GO:0035357
GeneOntologyBiologicalProcesspositive regulation of epidermal cell differentiation

MED1 ALOX15B

1.55e-0328432GO:0045606
GeneOntologyBiologicalProcessnucleobase-containing compound transport

CKAP5 POM121 NUP155 POM121B

1.77e-03249434GO:0015931
GeneOntologyBiologicalProcessregulation of heart contraction

CACNA1G NUP155 RNF207 MEF2A

1.77e-03249434GO:0008016
GeneOntologyBiologicalProcessepithelial cell differentiation

RHCG APC NRG1 MED1 ABI2 CUX1 ALOX15B

1.98e-03870437GO:0030855
GeneOntologyBiologicalProcesspositive regulation of epidermis development

MED1 ALOX15B

2.15e-0333432GO:0045684
GeneOntologyBiologicalProcessneuron projection organization

CKAP5 MAP1A ABI2

2.35e-03127433GO:0106027
GeneOntologyBiologicalProcessactin-mediated cell contraction

CACNA1G NUP155 RNF207

2.35e-03127433GO:0070252
GeneOntologyBiologicalProcessmodulation of chemical synaptic transmission

CKAP5 BSN MAP1A KCNQ4 PCLO IQSEC2

2.39e-03663436GO:0050804
GeneOntologyBiologicalProcessregulation of trans-synaptic signaling

CKAP5 BSN MAP1A KCNQ4 PCLO IQSEC2

2.41e-03664436GO:0099177
GeneOntologyBiologicalProcesspositive regulation of microtubule polymerization

CKAP5 APC

2.70e-0337432GO:0031116
GeneOntologyBiologicalProcessneuron development

APC NRG1 ARID1B SEMA6A MAP1A ABI2 MEF2A CDHR1 CUX1

2.77e-031463439GO:0048666
GeneOntologyBiologicalProcessepithelium development

RHCG APC NRG1 SPECC1L MED1 ABI2 RNF207 CUX1 ALOX15B

2.85e-031469439GO:0060429
GeneOntologyCellularComponentpresynaptic active zone cytoplasmic component

BSN PCLO IQSEC2

1.30e-0523423GO:0098831
GeneOntologyCellularComponentribbon synapse

BSN PCLO IQSEC2

3.59e-0532423GO:0097470
GeneOntologyCellularComponentdendrite

CKAP5 APC CACNA1G CTTNBP2 BSN MAP1A ABI2 DENND1A PCLO

4.17e-05858429GO:0030425
GeneOntologyCellularComponentdendritic tree

CKAP5 APC CACNA1G CTTNBP2 BSN MAP1A ABI2 DENND1A PCLO

4.25e-05860429GO:0097447
GeneOntologyCellularComponentcytoplasmic region

CKAP5 BSN EFCAB6 MAP1A PCLO IQSEC2

7.78e-05360426GO:0099568
GeneOntologyCellularComponentcell cortex region

BSN PCLO IQSEC2

1.01e-0445423GO:0099738
GeneOntologyCellularComponentcytoskeleton of presynaptic active zone

BSN PCLO

1.10e-048422GO:0048788
GeneOntologyCellularComponentpostsynapse

APC NRG1 CTTNBP2 BSN MAP1A ABI2 PCLO IQSEC2 APC2

1.55e-041018429GO:0098794
GeneOntologyCellularComponentpresynaptic active zone

NRG1 BSN PCLO IQSEC2

1.82e-04141424GO:0048786
GeneOntologyCellularComponentbeta-catenin destruction complex

APC APC2

3.03e-0413422GO:0030877
GeneOntologyCellularComponentpresynaptic cytoskeleton

BSN PCLO

3.53e-0414422GO:0099569
GeneOntologyCellularComponentsomatodendritic compartment

CKAP5 APC CACNA1G CTTNBP2 BSN MAP1A ABI2 DENND1A PCLO

6.20e-041228429GO:0036477
GeneOntologyCellularComponentpostsynaptic actin cytoskeleton

CTTNBP2 ABI2

6.59e-0419422GO:0098871
GeneOntologyCellularComponentcell cortex

APC CTTNBP2 BSN PCLO IQSEC2

8.50e-04371425GO:0005938
GeneOntologyCellularComponentadherens junction

APC ABI2 ALOX15B NECTIN2

8.51e-04212424GO:0005912
GeneOntologyCellularComponentnuclear pore

POM121 NUP155 POM121B

1.10e-03101423GO:0005643
GeneOntologyCellularComponentglutamatergic synapse

APC NRG1 CTTNBP2 BSN ABI2 PCLO IQSEC2

1.11e-03817427GO:0098978
GeneOntologyCellularComponentpostsynaptic cytoskeleton

CTTNBP2 ABI2

1.24e-0326422GO:0099571
GeneOntologyCellularComponentneuronal cell body

CKAP5 APC CACNA1G BSN MAP1A DENND1A PCLO

1.26e-03835427GO:0043025
GeneOntologyCellularComponentneuron projection cytoplasm

CKAP5 BSN MAP1A

1.40e-03110423GO:0120111
GeneOntologyCellularComponentinhibitory synapse

BSN PCLO

1.77e-0331422GO:0060077
GeneOntologyCellularComponentpresynapse

APC NRG1 CTTNBP2 BSN DENND1A PCLO IQSEC2

1.77e-03886427GO:0098793
GeneOntologyCellularComponentcatenin complex

APC APC2

1.88e-0332422GO:0016342
GeneOntologyCellularComponentpolymeric cytoskeletal fiber

CKAP5 APC SPECC1L EFCAB6 MAP1A ABI2 APC2

1.92e-03899427GO:0099513
GeneOntologyCellularComponentpostsynaptic density

NRG1 BSN MAP1A PCLO IQSEC2

2.02e-03451425GO:0014069
GeneOntologyCellularComponentcell body

CKAP5 APC CACNA1G BSN MAP1A DENND1A PCLO

2.31e-03929427GO:0044297
GeneOntologyCellularComponentcytoplasmic microtubule

APC EFCAB6 APC2

2.41e-03133423GO:0005881
GeneOntologyCellularComponentasymmetric synapse

NRG1 BSN MAP1A PCLO IQSEC2

2.57e-03477425GO:0032279
GeneOntologyCellularComponentfilamentous actin

SPECC1L APC2

2.65e-0338422GO:0031941
GeneOntologyCellularComponentactin filament

SPECC1L ABI2 APC2

3.14e-03146423GO:0005884
GeneOntologyCellularComponentpostsynaptic specialization

NRG1 BSN MAP1A PCLO IQSEC2

3.23e-03503425GO:0099572
GeneOntologyCellularComponentplasma membrane bounded cell projection cytoplasm

CKAP5 BSN EFCAB6 MAP1A

3.69e-03317424GO:0032838
GeneOntologyCellularComponentneuron to neuron synapse

NRG1 BSN MAP1A PCLO IQSEC2

3.81e-03523425GO:0098984
GeneOntologyCellularComponentmicrotubule

CKAP5 APC EFCAB6 MAP1A APC2

4.13e-03533425GO:0005874
GeneOntologyCellularComponentGABA-ergic synapse

NRG1 BSN PCLO

4.35e-03164423GO:0098982
GeneOntologyCellularComponentnuclear membrane

APC POM121 NUP155 POM121B

5.19e-03349424GO:0031965
GeneOntologyCellularComponentcell-cell junction

APC SPECC1L ABI2 ALOX15B NECTIN2

6.37e-03591425GO:0005911
GeneOntologyCellularComponentaxon cytoplasm

BSN MAP1A

8.25e-0368422GO:1904115
GeneOntologyCellularComponentaxon

APC NRG1 SEMA6A BSN MAP1A PCLO

8.34e-03891426GO:0030424
GeneOntologyCellularComponentsupramolecular fiber

CKAP5 APC SPECC1L EFCAB6 MAP1A ABI2 APC2

8.50e-031179427GO:0099512
GeneOntologyCellularComponentsupramolecular polymer

CKAP5 APC SPECC1L EFCAB6 MAP1A ABI2 APC2

8.81e-031187427GO:0099081
GeneOntologyCellularComponentperinuclear region of cytoplasm

APC CACNA1G RNF207 PCLO APC2 SEC16A

1.04e-02934426GO:0048471
GeneOntologyCellularComponentlamellipodium

APC ABI2 APC2

1.10e-02230423GO:0030027
GeneOntologyCellularComponentextrinsic component of membrane

APC BSN APC2

1.10e-02230423GO:0019898
GeneOntologyCellularComponentneuron projection terminus

APC BSN PCLO

1.14e-02233423GO:0044306
HumanPhenoAbnormality of the palpebral fissures

APC ZMYM2 CACNA1G ARID1B SPECC1L KMT2E CUX1 PCLO IQSEC2 APC2 BCORL1

1.73e-058801711HP:0008050
DomainZnf_piccolo

BSN PCLO

4.94e-062422IPR008899
Domainzf-piccolo

BSN PCLO

4.94e-062422PF05715
DomainAPC_dom

APC APC2

4.94e-062422IPR026831
DomainAPC_N

APC APC2

4.94e-062422IPR032038
DomainAPC_basic_dom

APC APC2

4.94e-062422IPR009234
DomainApc_fam

APC APC2

4.94e-062422IPR026818
DomainAPC_basic

APC APC2

4.94e-062422PF05956
DomainAPC_r

APC APC2

4.94e-062422PF05923
DomainSAMP

APC APC2

4.94e-062422PF05924
DomainAPC_rpt

APC APC2

4.94e-062422IPR009223
DomainSAMP

APC APC2

4.94e-062422IPR009224
DomainAPC_N_CC

APC APC2

4.94e-062422PF16689
Domain-

CKAP5 APC ARID1B APC2

1.53e-032224241.25.10.10
DomainArm

APC APC2

2.20e-0331422PF00514
DomainARM-like

CKAP5 APC ARID1B APC2

3.10e-03270424IPR011989
DomainARM

APC APC2

3.65e-0340422SM00185
DomainARM_REPEAT

APC APC2

3.65e-0340422PS50176
DomainZnf_FYVE_PHD

BSN KMT2E PCLO

4.38e-03147423IPR011011
DomainArmadillo

APC APC2

5.01e-0347422IPR000225
PathwayREACTOME_POSTMITOTIC_NUCLEAR_PORE_COMPLEX_NPC_REFORMATION

POM121 NUP155 POM121B

2.98e-0524363MM15658
PathwayREACTOME_NUCLEAR_PORE_COMPLEX_NPC_DISASSEMBLY

POM121 NUP155 POM121B

1.42e-0440363MM14945
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_BY_SMALL_RNAS

POM121 NUP155 POM121B

1.53e-0441363MM15200
PathwayREACTOME_SUMOYLATION_OF_SUMOYLATION_PROTEINS

POM121 NUP155 POM121B

1.64e-0442363MM15039
PathwayREACTOME_TRANSPORT_OF_THE_SLBP_DEPENDANT_MATURE_MRNA

POM121 NUP155 POM121B

1.76e-0443363MM14609
PathwayREACTOME_SUMOYLATION_OF_UBIQUITINYLATION_PROTEINS

POM121 NUP155 POM121B

2.30e-0447363MM14939
PathwayREACTOME_GENE_SILENCING_BY_RNA

POM121 NUP155 POM121B

2.60e-0449363MM14837
PathwayREACTOME_TRANSPORT_OF_MATURE_MRNAS_DERIVED_FROM_INTRONLESS_TRANSCRIPTS

POM121 NUP155 POM121B

2.76e-0450363MM14610
PathwayREACTOME_SUMOYLATION_OF_DNA_REPLICATION_PROTEINS

POM121 NUP155 POM121B

2.93e-0451363MM15151
PathwayREACTOME_NUCLEAR_ENVELOPE_BREAKDOWN

POM121 NUP155 POM121B

3.66e-0455363MM14917
PathwayREACTOME_SUMOYLATION_OF_RNA_BINDING_PROTEINS

POM121 NUP155 POM121B

4.29e-0458363MM15149
PathwayREACTOME_SNRNP_ASSEMBLY

POM121 NUP155 POM121B

4.29e-0458363MM14736
PathwayREACTOME_SUMOYLATION_OF_CHROMATIN_ORGANIZATION_PROTEINS

POM121 NUP155 POM121B

5.99e-0465363MM15147
PathwayBIOCARTA_PITX2_PATHWAY

APC MED1

6.52e-0415362MM1439
PathwayREACTOME_NUCLEAR_ENVELOPE_NE_REASSEMBLY

POM121 NUP155 POM121B

6.84e-0468363MM14921
PathwayBIOCARTA_PITX2_PATHWAY

APC MED1

7.44e-0416362M8516
PathwayREACTOME_REGULATION_OF_HSF1_MEDIATED_HEAT_SHOCK_RESPONSE

POM121 NUP155 POM121B

8.41e-0473363MM14948
PathwayREACTOME_SIGNALING_BY_CYTOSOLIC_FGFR1_FUSION_MUTANTS

ZMYM2 CUX1

9.46e-0418362M673
PathwayREACTOME_SENSORY_PROCESSING_OF_SOUND

BSN KCNQ4 PCLO

9.83e-0477363M41822
PathwayREACTOME_GLUCOSE_METABOLISM

POM121 NUP155 POM121B

1.18e-0382363MM15394
PathwayREACTOME_SUMOYLATION_OF_DNA_DAMAGE_RESPONSE_AND_REPAIR_PROTEINS

POM121 NUP155 POM121B

1.26e-0384363MM14929
PathwayREACTOME_TRANSPORT_OF_MATURE_TRANSCRIPT_TO_CYTOPLASM

POM121 NUP155 POM121B

1.35e-0386363MM15413
PathwayREACTOME_CELLULAR_RESPONSE_TO_HEAT_STRESS

POM121 NUP155 POM121B

1.64e-0392363MM14951
PathwayREACTOME_POSTMITOTIC_NUCLEAR_PORE_COMPLEX_NPC_REFORMATION

POM121 NUP155

2.14e-0327362M29807
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

CKAP5 APC ZMYM2 SPECC1L CTTNBP2 BSN ABI2 CUX1 IQSEC2 APC2 SEC16A

2.30e-08963441128671696
Pubmed

A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex.

ARID1B REPS1 MED1 MAP1A CUX1 NACA NECTIN2 SEC16A

1.25e-0747244838943005
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

CKAP5 APC ZMYM2 ZNF592 CUX1 BCORL1 SEC16A

9.00e-0741844734709266
Pubmed

Human transcription factor protein interaction networks.

NOLC1 ZMYM2 KLF3 ARID1B ATXN7L2 ZNF592 MEF2A CUX1 NACA BCORL1 SEC16A

1.19e-061429441135140242
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

CKAP5 APC NOLC1 NHSL1 BSN MAP1A ABI2 PCLO IQSEC2 NACA

1.23e-061139441036417873
Pubmed

Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.

APC ARID1B POM121 MED1 NUP155 ZNF592 SEC16A

1.27e-0644044734244565
Pubmed

Functional redundancy between Apc and Apc2 regulates tissue homeostasis and prevents tumorigenesis in murine mammary epithelium.

APC APC2

1.56e-06244227694902
Pubmed

Bassoon and Piccolo maintain synapse integrity by regulating protein ubiquitination and degradation.

BSN PCLO

1.56e-06244223403927
Pubmed

Role of Bassoon and Piccolo in Assembly and Molecular Organization of the Active Zone.

BSN PCLO

1.56e-06244226793095
Pubmed

Piccolo and bassoon maintain synaptic vesicle clustering without directly participating in vesicle exocytosis.

BSN PCLO

1.56e-06244220332206
Pubmed

Active zone density is conserved during synaptic growth but impaired in aged mice.

BSN PCLO

1.56e-06244221935939
Pubmed

APC2 is critical for ovarian WNT signalling control, fertility and tumour suppression.

APC APC2

1.56e-06244231291912
Pubmed

Dual-color STED microscopy reveals a sandwich structure of Bassoon and Piccolo in active zones of adult and aged mice.

BSN PCLO

1.56e-06244227321892
Pubmed

No symphony without bassoon and piccolo: changes in synaptic active zone proteins in Huntington's disease.

BSN PCLO

1.56e-06244232493491
Pubmed

Synaptic activity controls localization and function of CtBP1 via binding to Bassoon and Piccolo.

BSN PCLO

1.56e-06244225652077
Pubmed

Differential regulation of microtubule severing by APC underlies distinct patterns of projection neuron and interneuron migration.

APC CUX1 APC2

2.12e-062044325535916
Pubmed

Identification of the SOX2 Interactome by BioID Reveals EP300 as a Mediator of SOX2-dependent Squamous Differentiation and Lung Squamous Cell Carcinoma Growth.

ZMYM2 ARID1B MED1 CUX1

3.81e-068344428794006
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

NOLC1 CACNA1G ARID1B BSN NUP155 ZNF592 NACA

4.26e-0652944714621295
Pubmed

POM121 inhibits the macrophage inflammatory response by impacting NF-κB P65 nuclear accumulation.

POM121 POM121B

4.69e-06344230802453
Pubmed

Nucleoporin POM121 signals TFEB-mediated autophagy via activation of SIGMAR1/sigma-1 receptor chaperone by pridopidine.

POM121 POM121B

4.69e-06344235507432
Pubmed

Pom121 links two essential subcomplexes of the nuclear pore complex core to the membrane.

POM121 NUP155

4.69e-06344220974814
Pubmed

Functional comparison of human adenomatous polyposis coli (APC) and APC-like in targeting beta-catenin for degradation.

APC APC2

4.69e-06344223840886
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

APC NOLC1 SPECC1L NUP155 EFCAB6 CUX1 NECTIN2 SEC16A

5.21e-0677744835844135
Pubmed

Bulk and mosaic deletions of Egfr reveal regionally defined gliogenesis in the developing mouse forebrain.

APC NRG1 CUX1

5.41e-062744336915679
Pubmed

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.

CKAP5 NOLC1 ZMYM2 ARID1B MED1 DAZAP1 MEF2A CUX1 BCORL1

8.20e-06110344934189442
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

CKAP5 APC NHSL1 SPECC1L CTTNBP2 BSN MAP1A PCLO IQSEC2 SEC16A

9.30e-061431441037142655
Pubmed

Two distinct human POM121 genes: requirement for the formation of nuclear pore complexes.

POM121 POM121B

9.37e-06444217900573
Pubmed

A novel GSK3-regulated APC:Axin interaction regulates Wnt signaling by driving a catalytic cycle of efficient βcatenin destruction.

APC APC2

9.37e-06444226393419
Pubmed

Identification and functional characterization of transcriptional activators in human cells.

APC ARID1B CUX1 PCLO BCORL1 SEC16A

1.06e-0539844635016035
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

CKAP5 APC NOLC1 NHSL1 DENND1A IQSEC2 NECTIN2 SEC16A

1.10e-0586144836931259
Pubmed

Fine-scale comparative mapping of the human 7q11.23 region and the orthologous region on mouse chromosome 5G: the low-copy repeats that flank the Williams-Beuren syndrome deletion arose at breakpoint sites of an evolutionary inversion(s).

POM121 POM121B CUX1

1.20e-053544311013070
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

CKAP5 APC ZMYM2 SPECC1L REPS1 MED1 ZNF592 ABI2 DENND1A NACA

1.38e-051497441031527615
Pubmed

A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.

NHSL1 SEMA6A NUP155 ABI2 NECTIN2 SEC16A

1.45e-0542144636976175
Pubmed

Peering through the pore: nuclear pore complex structure, assembly, and function.

POM121 NUP155 POM121B

1.55e-053844312791264
Pubmed

Generation and comparative analysis of approximately 3.3 Mb of mouse genomic sequence orthologous to the region of human chromosome 7q11.23 implicated in Williams syndrome.

POM121 POM121B CUX1

1.55e-053844311779826
Pubmed

Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.

POM121 BSN NUP155 KMT2E MAP1A APC2

1.64e-0543044635044719
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

CKAP5 NOLC1 ZMYM2 REPS1 MED1 MAP1A NACA SEC16A

1.97e-0593444833916271
Pubmed

RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.

CKAP5 APC POM121 NUP155 SEC16A

2.03e-0526344534702444
Pubmed

Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.

ZMYM2 ARID1B MED1 MEF2A CUX1

2.22e-0526844533640491
Pubmed

Protein interaction studies in human induced neurons indicate convergent biology underlying autism spectrum disorders.

APC ARID1B MAP1A

2.25e-054344336950384
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

NOLC1 ZMYM2 ARID1B MED1 DAZAP1 CUX1 BCORL1 SEC16A

2.30e-0595444836373674
Pubmed

The F-box protein beta-TrCP associates with phosphorylated beta-catenin and regulates its activity in the cell.

APC APC2

2.34e-05644210074433
Pubmed

A protein interaction node at the neurotransmitter release site: domains of Aczonin/Piccolo, Bassoon, CAST, and rim converge on the N-terminal domain of Munc13-1.

BSN PCLO

2.34e-05644219812333
Pubmed

Essential Roles for ARID1B in Dendritic Arborization and Spine Morphology of Developing Pyramidal Neurons.

ARID1B CUX1

2.34e-05644226937011
Pubmed

Physical and functional interaction of the active zone proteins, CAST, RIM1, and Bassoon, in neurotransmitter release.

BSN PCLO

2.34e-05644214734538
Pubmed

BioID identifies novel c-MYC interacting partners in cultured cells and xenograft tumors.

ZMYM2 ARID1B ATXN7L2 MED1

2.54e-0513444425452129
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

CKAP5 APC ZMYM2 REPS1 DAZAP1 ZNF592 CUX1 IQSEC2 APC2

2.75e-05128544935914814
Pubmed

A human MAP kinase interactome.

APC ZMYM2 SPECC1L POM121 MAP1A CUX1

3.25e-0548644620936779
Pubmed

Domains of axin involved in protein-protein interactions, Wnt pathway inhibition, and intracellular localization.

APC APC2

3.27e-05744210330403
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

CKAP5 NOLC1 SPECC1L POM121 NUP155 DAZAP1 NACA SEC16A

3.80e-05102444824711643
Pubmed

Differential roles of ARID1B in excitatory and inhibitory neural progenitors in the developing cortex.

ARID1B CUX1

4.36e-05844233594090
Pubmed

Downregulation of beta-catenin by human Axin and its association with the APC tumor suppressor, beta-catenin and GSK3 beta.

APC APC2

5.60e-0594429601641
Pubmed

Superresolution imaging of chemical synapses in the brain.

BSN PCLO

5.60e-05944221144999
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

ARID1B SPECC1L REPS1 MED1 CUX1 SEC16A

6.39e-0554944638280479
Pubmed

Interaction network of human early embryonic transcription factors.

ZMYM2 KLF3 ARID1B BCORL1 SEC16A

8.00e-0535144538297188
Pubmed

Spike S1 domain interactome in non-pulmonary systems: A role beyond the receptor recognition.

NOLC1 MED1 NUP155 NACA

8.36e-0518244436225252
Pubmed

Early postnatal serotonin modulation prevents adult-stage deficits in Arid1b-deficient mice through synaptic transcriptional reprogramming.

ARID1B CUX1

8.54e-051144236030255
Pubmed

Evidence that descending cortical axons are essential for thalamocortical axons to cross the pallial-subpallial boundary in the embryonic forebrain.

APC NRG1

8.54e-051144222412988
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

APC ZMYM2 BSN MAP1A BCORL1 SEC16A

9.31e-0558844638580884
Pubmed

Ulk4 Regulates Neural Stem Cell Pool.

APC CUX1

1.02e-041244227300315
Pubmed

Multiple roles of integrin-α3 at the neuromuscular junction.

BSN PCLO

1.02e-041244228386022
Pubmed

Loss of Tsc2 in radial glia models the brain pathology of tuberous sclerosis complex in the mouse.

APC CUX1

1.02e-041244219150975
Pubmed

HectD1 E3 ligase modifies adenomatous polyposis coli (APC) with polyubiquitin to promote the APC-axin interaction.

APC CTTNBP2

1.21e-041344223277359
Pubmed

LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.

CKAP5 SPECC1L MED1 SEC16A

1.25e-0420244433005030
Pubmed

Probing nuclear pore complex architecture with proximity-dependent biotinylation.

APC POM121 NUP155

1.29e-047744324927568
Pubmed

Neurocalcin Delta Knockout Impairs Adult Neurogenesis Whereas Half Reduction Is Not Pathological.

APC CUX1

1.41e-041444230853885
Pubmed

Mutation of the BiP/GRP78 gene causes axon outgrowth and fasciculation defects in the thalamocortical connections of the mammalian forebrain.

SEMA6A CUX1

1.41e-041444222821687
Pubmed

APOE and BCHE as modulators of cerebral amyloid deposition: a florbetapir PET genome-wide association study.

ARID1B NECTIN2

1.41e-041444223419831
Pubmed

Calcium channels link the muscle-derived synapse organizer laminin β2 to Bassoon and CAST/Erc2 to organize presynaptic active zones.

BSN PCLO

1.41e-041444221228161
Pubmed

Impaired maturation of dendritic spines without disorganization of cortical cell layers in mice lacking NRG1/ErbB signaling in the central nervous system.

NRG1 CUX1

1.41e-041444219240213
Pubmed

O-linked N-acetylglucosamine proteomics of postsynaptic density preparations using lectin weak affinity chromatography and mass spectrometry.

BSN PCLO

1.41e-041444216452088
Pubmed

Interactomes of Glycogen Synthase Kinase-3 Isoforms.

APC NHSL1 MAP1A SEC16A

1.42e-0420944436779422
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

ZMYM2 ARID1B MED1 BSN CUX1 BCORL1

1.45e-0463844631182584
Pubmed

Proximity labeling of endogenous RICTOR identifies mTOR complex 2 regulation by ADP ribosylation factor ARF1.

CKAP5 APC CUX1 NACA

1.59e-0421544435973513
Pubmed

Gene-specific requirement for P-TEFb activity and RNA polymerase II phosphorylation within the p53 transcriptional program.

APC APC2

1.63e-041544216510875
Pubmed

Dephosphorylation of the transcriptional cofactor NACA by the PP1A phosphatase enhances cJUN transcriptional activity and osteoblast differentiation.

SPECC1L NACA

1.63e-041544230948508
Pubmed

Directional neuronal migration is impaired in mice lacking adenomatous polyposis coli 2.

CUX1 APC2

1.63e-041544222573669
Pubmed

Limited expression of nuclear pore membrane glycoprotein 210 in cell lines and tissues suggests cell-type specific nuclear pores in metazoans.

POM121 POM121B

1.63e-041544214697343
Pubmed

Modifier genes and protective alleles in humans and mice.

APC MAP1A

1.86e-041644212787792
Pubmed

Genome-wide association analysis of age-at-onset in Alzheimer's disease.

ZNF592 NECTIN2

2.10e-041744222005931
Pubmed

Elp2 mutations perturb the epitranscriptome and lead to a complex neurodevelopmental phenotype.

APC CUX1

2.10e-041744233976153
Pubmed

Fstl1 is involved in the regulation of radial glial scaffold development.

APC CUX1

2.10e-041744226382033
Pubmed

The DNA sequence of human chromosome 7.

CTTNBP2 POM121 POM121B CUX1 PCLO

2.32e-0444144512853948
Pubmed

Targeted and Interactome Proteomics Revealed the Role of PHD2 in Regulating BRD4 Proline Hydroxylation.

CKAP5 NOLC1 MED1 ZNF592 NACA

2.32e-0444144531239290
Pubmed

Identification of proximal SUMO-dependent interactors using SUMO-ID.

ZMYM2 REPS1 MED1 MAP1A SEC16A

2.39e-0444444534795231
Pubmed

Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.

APC ARID1B CTTNBP2 DENND1A SEC16A

2.44e-0444644524255178
Pubmed

BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.

CKAP5 APC REPS1 NUP155 NECTIN2 SEC16A

2.55e-0470844639231216
Pubmed

Cell-Intrinsic Control of Interneuron Migration Drives Cortical Morphogenesis.

NRG1 CUX1

2.64e-041944229474907
Pubmed

Comparative Application of BioID and TurboID for Protein-Proximity Biotinylation.

ARID1B POM121 NUP155 DAZAP1 SEC16A

2.73e-0445744532344865
Pubmed

Identification of Human Neuronal Protein Complexes Reveals Biochemical Activities and Convergent Mechanisms of Action in Autism Spectrum Disorders.

POM121 CUX1 SEC16A

2.89e-0410144326949739
Pubmed

Cell Metabolic Alterations due to Mcph1 Mutation in Microcephaly.

APC CUX1

2.93e-042044232294449
Pubmed

Loss of BAF Complex in Developing Cortex Perturbs Radial Neuronal Migration in a WNT Signaling-Dependent Manner.

ARID1B CUX1

2.93e-042044234220450
Pubmed

Neural crest-derived neurons invade the ovary but not the testis during mouse gonad development.

NRG1 SEMA6A

2.93e-042044230819894
Pubmed

The CSF-1 receptor ligands IL-34 and CSF-1 exhibit distinct developmental brain expression patterns and regulate neural progenitor cell maintenance and maturation.

APC CUX1

2.93e-042044222542597
Pubmed

NuRD subunit CHD4 regulates super-enhancer accessibility in rhabdomyosarcoma and represents a general tumor dependency.

NOLC1 ZMYM2 ZNF592

3.06e-0410344332744500
Pubmed

The PHLPP1 N-Terminal Extension Is a Mitotic Cdk1 Substrate and Controls an Interactome Switch.

CKAP5 APC NACA SEC16A

3.09e-0425644433397691
Pubmed

Direct binding of CoREST1 to SUMO-2/3 contributes to gene-specific repression by the LSD1/CoREST1/HDAC complex.

ZMYM2 ZMAT3 CUX1

3.33e-0410644319394292
Pubmed

LINKIN, a new transmembrane protein necessary for cell adhesion.

CKAP5 REPS1 MAP1A MEF2A NACA

3.42e-0448044525437307
Pubmed

CHK2-BRCA1 tumor-suppressor axis restrains oncogenic Aurora-A kinase to ensure proper mitotic microtubule assembly.

CKAP5 NOLC1 NUP155 NACA SEC16A

3.90e-0449444526831064
Pubmed

A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.

ARID1B CTTNBP2 REPS1 KMT2E ZNF592

4.01e-0449744523414517
InteractionCTBP1 interactions

APC ZMYM2 KLF3 MED1 DAZAP1 PCLO BCORL1 SEC16A

1.98e-06406438int:CTBP1
InteractionPHF21A interactions

CKAP5 APC ZMYM2 KLF3 ZNF592 BCORL1 SEC16A

7.40e-06343437int:PHF21A
InteractionRCOR1 interactions

CKAP5 APC ZMYM2 KLF3 ZNF592 CUX1 BCORL1 SEC16A

8.40e-06494438int:RCOR1
InteractionMAPRE3 interactions

CKAP5 APC SPECC1L CTTNBP2 MAP1A APC2

8.87e-06230436int:MAPRE3
InteractionMAPRE1 interactions

CKAP5 APC SPECC1L REPS1 NUP155 POM121B APC2 SEC16A

1.12e-05514438int:MAPRE1
InteractionYWHAH interactions

CKAP5 APC NOLC1 NHSL1 SPECC1L MED1 ABI2 DENND1A IQSEC2 NECTIN2 SEC16A

1.42e-0511024311int:YWHAH
InteractionKCNA3 interactions

CKAP5 APC SPECC1L REPS1 BSN NUP155 NACA NECTIN2 SEC16A

7.57e-05871439int:KCNA3
InteractionTAF5L interactions

ZMYM2 KLF3 ATXN7L2 ALOX15B

7.90e-05107434int:TAF5L
InteractionC10orf88 interactions

REPS1 NUP155 ABI2 DENND1A

9.77e-05113434int:C10orf88
InteractionFMR1 interactions

CKAP5 APC BSN DAZAP1 CUX1 IQSEC2 APC2

1.27e-04536437int:FMR1
InteractionSOX2 interactions

CKAP5 ZMYM2 KLF3 ARID1B SPECC1L MED1 DAZAP1 MAP1A MEF2A CUX1 SEC16A

1.46e-0414224311int:SOX2
InteractionAP2S1 interactions

APC REPS1 MAP1A NACA

1.68e-04130434int:AP2S1
GeneFamilyZinc fingers|Zinc fingers PARP-type|Poly(ADP-ribose) polymerases

BSN PCLO

3.14e-041532226
GeneFamilyNucleoporins

POM121 NUP155

1.46e-03323221051
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

APC APC2

2.62e-0343322409
ToppCell368C-Lymphocytic-NK_cells-NK_cell_E|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

RNF207 MEF2A PCLO BCORL1

2.78e-05177444946803293a7955116c80f403e99e4093e798ca3f
ToppCelldroplet-Lung-30m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SEMA6A CTTNBP2 RNF207 NECTIN2

3.74e-0519144451cff0594ac7ad8c065c8ea2301f8c149bd062b4
ToppCelldroplet-Lung-30m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SEMA6A CTTNBP2 RNF207 NECTIN2

3.74e-05191444a55b6f0a7ec1a8852ffca593cfdccd7edea09b7b
ToppCelldroplet-Lung-30m-Endothelial-lymphatic_endothelial|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SEMA6A CTTNBP2 RNF207 NECTIN2

3.74e-0519144438681a1b182d6af5cce85db5431b6eba4b20ad96
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Newborn-22|World / Primary Cells by Cluster

NHSL1 CTTNBP2 CUX1 NACA

3.90e-051934443b927d4b8ecb21a408424ef91a23746c21741f49
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-3_mon|organoid_Paulsen_bioRxiv / Sample Type, Dataset, Time_group, and Cell type.

NHSL1 MAP1A PCLO NACA

3.98e-051944444903a0d6e36599bcb83b179462e5b949df9eb685
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Newborn|World / Primary Cells by Cluster

NHSL1 CTTNBP2 CUX1 NACA

4.14e-051964449401bd84798f0ea3e986e94135a9e1dc5643330f
ToppCell(5)_Epithelial_cells-(5)_Epi_stratified|(5)_Epithelial_cells / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)

RHCG CTTNBP2 DYNAP ALOX15B

4.30e-05198444b3aec042912ce53bd86e86b6761a0604d9998ab5
DrugPrimaquine diphosphate [63-45-6]; Up 200; 8.8uM; MCF7; HT_HG-U133A

NRG1 MAP1A CDHR1 ALOX15B IQSEC2 NACA

1.71e-061954364845_UP
DrugBretylium tosylate [61-75-6]; Up 200; 9.6uM; HL60; HT_HG-U133A

NRG1 CACNA1G SEMA6A MAP1A PCLO APC2

1.98e-062004363057_UP
Diseasefamilial adenomatous polyposis 1 (implicated_via_orthology)

APC APC2

2.07e-062432DOID:0080409 (implicated_via_orthology)
DiseaseIntellectual Disability

APC ZMYM2 CACNA1G SPECC1L KMT2E APC2

4.43e-05447436C3714756
DiseaseAlzheimer disease, amyloid-beta measurement

ARID1B NECTIN2

3.13e-0418432EFO_0005194, MONDO_0004975
DiseaseNeurodevelopmental Disorders

ARID1B KMT2E IQSEC2

3.41e-0493433C1535926
Diseasephysical activity measurement

APC REPS1 CUX1 NECTIN2

4.44e-04245434EFO_0008002
DiseaseJT interval

RNF207 KCNQ4 CUX1 NACA

4.65e-04248434EFO_0007885
Diseasecortical surface area measurement

APC NHSL1 ARID1B SEMA6A CTTNBP2 REPS1 DENND1A CUX1

6.37e-041345438EFO_0010736
DiseaseMalignant neoplasm of breast

NRG1 ARID1B DAZAP1 CUX1 APC2 NECTIN2 BCORL1

8.50e-041074437C0006142
Diseasecolorectal cancer (implicated_via_orthology)

APC APC2

8.79e-0430432DOID:9256 (implicated_via_orthology)
DiseaseHirschsprung Disease

NRG1 ARID1B

9.39e-0431432C0019569
Diseaseelectrocardiography

NRG1 CACNA1G ZNF592 RNF207 KCNQ4

1.01e-03530435EFO_0004327
DiseaseMental Retardation, Psychosocial

APC ZMYM2 CACNA1G

1.10e-03139433C0025363
DiseaseProfound Mental Retardation

APC ZMYM2 CACNA1G

1.10e-03139433C0020796
DiseaseMental deficiency

APC ZMYM2 CACNA1G

1.10e-03139433C0917816
DiseaseInflammatory Bowel Diseases

APC APC2

1.20e-0335432C0021390
Diseasenasopharyngeal neoplasm

MED1 KCNQ4 PCLO

1.40e-03151433EFO_0004252

Protein segments in the cluster

PeptideGeneStartEntry
PPKPKTMGSPVQSTL

CDHR1

826

Q96JP9
LPSSPIVPMSKPTKP

CUX1

911

P39880
PSGSSAPPHPAKMPS

BCORL1

571

Q5H9F3
PLSPSPMKTPPAAAV

SPECC1L

866

Q69YQ0
KPPTPASTPHGQMTP

ARID1B

1281

Q8NFD5
PPSQAAPDMSKPPTA

DAZAP1

326

Q96EP5
TKDSPGKPPMAPPSK

ATXN7L2

176

Q5T6C5
PPTQKPPSPPMSGKG

ABI2

176

Q9NYB9
PMKNKPGPYSSVPPP

NOLC1

281

Q14978
TPSSPKSPPSEMSPP

NRG1

441

Q02297
SMPSSSPPIKKYSPP

KLF3

96

P57682
TVKMASPPPSGPPSA

MAP1A

991

P78559
SKRGKGPFQMPPPPT

IQSEC2

1211

Q5JU85
MKDSATSPPSPPLPS

KIAA1109

3916

Q2LD37
PSKQHLAPPTMPTSP

KCNQ4

451

P56696
PGPMGPKHPSKSLAP

BSN

3336

Q9UPA5
MKKLDPAVGSPPAPP

NHSL1

921

Q5SYE7
PDAKPMPKGSPTPPG

PCLO

866

Q9Y6V0
PPKMSKPGSPGSVIP

KMT2E

1351

Q8IZD2
SLGKVMPTKSPPPPG

MEF2A

246

Q02078
PKKPGPPVLSSDPNM

NUP155

996

O75694
APAAAPTPAPPSMIK

POM121B

586

A6NF01
PAPSMVPATDTKAPP

POM121

666

Q96HA1
SPGQTMPPSRSKTPP

APC2

1201

O95996
PAKPAPPTKATSKPM

CKAP5

1081

Q14008
PPTKATSKPMGGSAP

CKAP5

1086

Q14008
KISKHMTPPAPCPGP

CACNA1G

2186

O43497
AEKMPKGPPPTSPKA

EFCAB6

1146

Q5THR3
KLPLTMPVKPSTGSP

CTTNBP2

321

Q8WZ74
MAIPSKPPAASPEKP

DENND1A

646

Q8TEH3
KPGTPSPACPPTMTT

DYNAP

161

Q8N1N2
ASPMKPVPGTPPSSK

MED1

1206

Q15648
PPSMQLPPPTSKGLA

ALOX15B

571

O15296
PSPVGKMSGSPVQKP

RNF207

386

Q6ZRF8
GSPAEAPPSKSPSMP

REPS1

391

Q96D71
SPGQTMPPSRSKTPP

APC

1426

P25054
PPSSHKTSEMPPVPG

TIGD3

371

Q6B0B8
KAPPPPPTSMPKTVQ

SEC16A

2151

O15027
PPTSMPKTVQAAPPA

SEC16A

2156

O15027
PSGSSMPTADPKPPA

SRRM5

16

B3KS81
PPKPSFAPLSTSMKP

SEMA6A

1011

Q9H2E6
GSPKMPKSPKSPRSP

ZNF592

321

Q92610
PTFKPSGPSVPSVPM

RHCG

451

Q9UBD6
TGSAPPPSPTPNKEM

ZMYM2

831

Q9UBW7
PPKQPSPSPPMSVAT

ZMAT3

11

Q9HA38
PSHKGGPAMTPPSPK

NACA

1376

E9PAV3
PAMTVPSPKKTPAIP

NACA

1551

E9PAV3
NMPTPKSAGIPVPTP

NACA

1861

E9PAV3
HPKMGPSFPSPKPGS

NECTIN2

86

Q92692