Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	endothelin receptor activity	EDNRA EDNRB	6.54e-06	3	30	2	GO:0004962
GeneOntologyMolecularFunction	RNA nuclease activity	PDE12 ELAC2 ERI3	1.10e-03	136	30	3	GO:0004540
GeneOntologyMolecularFunction	3'-5'-RNA exonuclease activity	PDE12 ERI3	1.41e-03	37	30	2	GO:0000175
GeneOntologyMolecularFunction	RNA exonuclease activity, producing 5'-phosphomonoesters	PDE12 ERI3	1.64e-03	40	30	2	GO:0016896
GeneOntologyBiologicalProcess	innervation	ITGA4 FBXO45 EDNRA	1.78e-05	34	31	3	GO:0060384
GeneOntologyBiologicalProcess	nerve development	ITGA4 FBXO45 CNGB1 EDNRA	2.08e-05	109	31	4	GO:0021675
GeneOntologyBiologicalProcess	renal albumin absorption	EDNRA EDNRB	6.09e-05	8	31	2	GO:0097018
GeneOntologyBiologicalProcess	face development	ITGA4 EDNRA KAT6A	1.15e-04	63	31	3	GO:0060324
GeneOntologyBiologicalProcess	axonogenesis involved in innervation	ITGA4 EDNRA	1.19e-04	11	31	2	GO:0060385
GeneOntologyBiologicalProcess	renal protein absorption	EDNRA EDNRB	1.43e-04	12	31	2	GO:0097017
GeneOntologyBiologicalProcess	endothelin receptor signaling pathway	EDNRA EDNRB	1.69e-04	13	31	2	GO:0086100
GeneOntologyBiologicalProcess	enteric nervous system development	EDNRA EDNRB	1.97e-04	14	31	2	GO:0048484
GeneOntologyBiologicalProcess	mesenchyme development	GATA4 CUL7 ITGA4 EDNRA EDNRB	2.15e-04	372	31	5	GO:0060485
GeneOntologyBiologicalProcess	cellular response to follicle-stimulating hormone stimulus	GATA4 EDNRA	2.27e-04	15	31	2	GO:0071372
GeneOntologyBiologicalProcess	renal sodium ion absorption	EDNRA EDNRB	2.27e-04	15	31	2	GO:0070294
GeneOntologyBiologicalProcess	heparin metabolic process	EDNRA EDNRB	2.93e-04	17	31	2	GO:0030202
GeneOntologyBiologicalProcess	renal sodium ion transport	EDNRA EDNRB	3.29e-04	18	31	2	GO:0003096
GeneOntologyBiologicalProcess	response to follicle-stimulating hormone	GATA4 EDNRA	4.51e-04	21	31	2	GO:0032354
GeneOntologyBiologicalProcess	podocyte differentiation	EDNRA EDNRB	4.96e-04	22	31	2	GO:0072112
GeneOntologyBiologicalProcess	glomerular epithelial cell differentiation	EDNRA EDNRB	4.96e-04	22	31	2	GO:0072311
GeneOntologyBiologicalProcess	cellular response to gonadotropin stimulus	GATA4 EDNRA	4.96e-04	22	31	2	GO:0071371
GeneOntologyBiologicalProcess	renal filtration cell differentiation	EDNRA EDNRB	4.96e-04	22	31	2	GO:0061318
GeneOntologyBiologicalProcess	glomerular epithelium development	EDNRA EDNRB	5.42e-04	23	31	2	GO:0072010
GeneOntologyBiologicalProcess	vasoconstriction	ITGA4 EDNRA EDNRB	7.85e-04	121	31	3	GO:0042310
Domain	Endthln_rcpt	EDNRA EDNRB	2.49e-06	2	30	2	IPR000499
Domain	GPCR_Rhodpsn_7TM	OR8S1 OR10G2 OR7G3 EDNRA EDNRB	3.96e-03	670	30	5	IPR017452
Domain	7tm_1	OR8S1 OR10G2 OR7G3 EDNRA EDNRB	4.14e-03	677	30	5	PF00001
Domain	G_PROTEIN_RECEP_F1_1	OR8S1 OR10G2 OR7G3 EDNRA EDNRB	4.35e-03	685	30	5	PS00237
Domain	G_PROTEIN_RECEP_F1_2	OR8S1 OR10G2 OR7G3 EDNRA EDNRB	4.52e-03	691	30	5	PS50262
Domain	GPCR_Rhodpsn	OR8S1 OR10G2 OR7G3 EDNRA EDNRB	4.54e-03	692	30	5	IPR000276
Pubmed	GATA6 is a regulator of sinus node development and heart rhythm.	GATA4 EDNRA EDNRB	7.23e-07	20	31	3	33443158
Pubmed	Associations of EDNRA and EDNRB Polymorphisms with Intracerebral Hemorrhage.	EDNRA EDNRB	7.69e-07	2	31	2	31150867
Pubmed	Molecular characterization and regulation of the human endothelin receptors.	EDNRA EDNRB	7.69e-07	2	31	2	8440682
Pubmed	Altered expression and signal transduction of endothelin-1 receptors in heritable and idiopathic pulmonary arterial hypertension.	EDNRA EDNRB	7.69e-07	2	31	2	22688668
Pubmed	ETA and ETB receptors are expressed in vascular adventitial fibroblasts.	EDNRA EDNRB	7.69e-07	2	31	2	21949113
Pubmed	Facial hyperalgesia due to direct action of endothelin-1 in the trigeminal ganglion of mice.	EDNRA EDNRB	7.69e-07	2	31	2	29570803
Pubmed	Endothelin antagonism in portal hypertensive mice: implications for endothelin receptor-specific signaling in liver disease.	EDNRA EDNRB	7.69e-07	2	31	2	19299580
Pubmed	Agonist-promoted ubiquitination differentially regulates receptor trafficking of endothelin type A and type B receptors.	EDNRA EDNRB	7.69e-07	2	31	2	25381251
Pubmed	Endothelin receptor heteromerization inhibits β-arrestin function in HEK293 cells.	EDNRA EDNRB	7.69e-07	2	31	2	32744876
Pubmed	Identification of a novel role for endothelins within the oviduct.	EDNRA EDNRB	7.69e-07	2	31	2	20357223
Pubmed	Expression of endothelin receptors in frog, chicken, mouse and human pigment cells.	EDNRA EDNRB	7.69e-07	2	31	2	16962346
Pubmed	Effects of endothelin-related gene polymorphisms and aerobic exercise habit on age-related arterial stiffening: a 10-yr longitudinal study.	EDNRA EDNRB	7.69e-07	2	31	2	29097630
Pubmed	The expression of endothelin type A and B receptors in the lateral wall of the mouse cochlea.	EDNRA EDNRB	7.69e-07	2	31	2	17607529
Pubmed	The contractile effects of endothelins on isolated isthmic segment of human oviduct at the luteal phase of the menstrual cycle.	EDNRA EDNRB	7.69e-07	2	31	2	20401344
Pubmed	Elevation of blood pressure by genetic and pharmacological disruption of the ETB receptor in mice.	EDNRA EDNRB	7.69e-07	2	31	2	10198387
Pubmed	Increased gene expression and production of murine endothelin receptors after birth.	EDNRA EDNRB	7.69e-07	2	31	2	12763050
Pubmed	[Molecular cloning of human endothelin receptors and their expression in vascular endothelial cells and smooth muscle cells].	EDNRA EDNRB	7.69e-07	2	31	2	1291713
Pubmed	Role of ET(A) receptors in the vasoconstriction induced by endothelin-1 in subcutaneous small arteries of normotensive subjects and hypertensive patients.	EDNRA EDNRB	7.69e-07	2	31	2	11930911
Pubmed	Down-regulation of ETA receptors in ETB receptor-deficient mice.	EDNRA EDNRB	7.69e-07	2	31	2	15838300
Pubmed	Real-time polymerase chain reaction quantification of gene expression levels of murine endothelin-A and endothelin-B receptors: gene expression profiles by the standard curve method.	EDNRA EDNRB	7.69e-07	2	31	2	15838311
Pubmed	Comparison of endothelin receptors in normal versus cirrhotic human liver and in the liver from endothelial cell-specific ETB knockout mice.	EDNRA EDNRB	7.69e-07	2	31	2	22365955
Pubmed	Blood pressure regulation by ETA and ETB receptors in conscious, telemetry-instrumented mice and role of ETA in hypertension produced by selective ETB blockade.	EDNRA EDNRB	7.69e-07	2	31	2	16399858
Pubmed	Endothelin receptor pharmacology and function in the mouse: comparison with rat and man.	EDNRA EDNRB	7.69e-07	2	31	2	15838332
Pubmed	Comparison of endothelin-A and endothelin-B receptor distribution visualized by radioligand binding versus immunocytochemical localization using subtype selective antisera.	EDNRA EDNRB	7.69e-07	2	31	2	15838285
Pubmed	Expression of endothelin receptor subtypes in bronchial tumors.	EDNRA EDNRB	7.69e-07	2	31	2	20043107
Pubmed	Modulation of endothelin receptors in the failing right ventricle of the heart and vasculature of the lung in human pulmonary arterial hypertension.	EDNRA EDNRB	7.69e-07	2	31	2	24582810
Pubmed	Upregulation of vascular ET(B) receptor gene expression after chronic ET(A) receptor blockade in prediabetic NOD mice.	EDNRA EDNRB	7.69e-07	2	31	2	15838254
Pubmed	Functional diversity of endothelin pathways in human lung fibroblasts may be based on structural diversity of the endothelin receptors.	EDNRA EDNRB	7.69e-07	2	31	2	14636059
Pubmed	Role of endothelin-1 and its receptors, ETA and ETB, in the survival of human vascular endothelial cells.	EDNRA EDNRB	7.69e-07	2	31	2	28732172
Pubmed	Ovarian hormones modulate endothelin-1 receptor responses in young women.	EDNRA EDNRB	7.69e-07	2	31	2	29999581
Pubmed	Targeting endothelin receptors A and B attenuates the inflammatory response and improves locomotor function following spinal cord injury in mice.	EDNRA EDNRB	7.69e-07	2	31	2	24756152
Pubmed	Cloning and chromosomal localization of a human endothelin ETA receptor.	EDNRA EDNRB	7.69e-07	2	31	2	1659806
Pubmed	Combined knockout of collecting duct endothelin A and B receptors causes hypertension and sodium retention.	EDNRA EDNRB	7.69e-07	2	31	2	18784261
Pubmed	Endothelin receptor blockade inhibits molecular effectors of Kaposi's sarcoma cell invasion and tumor growth in vivo.	EDNRA EDNRB	7.69e-07	2	31	2	12875994
Pubmed	Up-regulation of endothelin receptors induced by cigarette smoke--involvement of MAPK in vascular and airway hyper-reactivity.	EDNRA EDNRB	7.69e-07	2	31	2	21057729
Pubmed	Selective in vivo antagonism of endothelin receptors in transforming growth factor-beta1 transgenic mice that mimic the vascular pathology of Alzheimer's disease.	EDNRA EDNRB	7.69e-07	2	31	2	20628431
Pubmed	Endothelin ETA and ETB receptor expression in the human trigeminal ganglion.	EDNRA EDNRB	7.69e-07	2	31	2	16816835
Pubmed	Ischemic heart disease induces upregulation of endothelin receptor mRNA in human coronary arteries.	EDNRA EDNRB	7.69e-07	2	31	2	14729387
Pubmed	Association between migraine and endothelin type A receptor (ETA -231 A/G) gene polymorphism.	EDNRA EDNRB	7.69e-07	2	31	2	11376172
Pubmed	C-terminus of ETA/ETB receptors regulate endothelin-1 signal transmission.	EDNRA EDNRB	2.31e-06	3	31	2	23436727
Pubmed	Altered role of smooth muscle endothelin receptors in coronary endothelin-1 and alpha1-adrenoceptor-mediated vasoconstriction in Type 2 diabetes.	EDNRA EDNRB	2.31e-06	3	31	2	17660396
Pubmed	New concepts in endothelin control of sodium balance.	EDNRA EDNRB	2.31e-06	3	31	2	21418087
Pubmed	Expression of endothelin-1, endothelin-A, and endothelin-B receptor in human breast cancer and correlation with long-term follow-up.	EDNRA EDNRB	2.31e-06	3	31	2	14519635
Pubmed	Functional coupling of G proteins to endothelin receptors is ligand and receptor subtype specific.	EDNRA EDNRB	2.31e-06	3	31	2	10789830
Pubmed	Transforming growth factor-β regulates endothelin-1 signaling in the newborn mouse lung during hypoxia exposure.	EDNRA EDNRB	2.31e-06	3	31	2	22287612
Pubmed	Endothelin-1 and its receptors on haemorrhoidal tissue: a potential site for therapeutic intervention.	EDNRA EDNRB	2.31e-06	3	31	2	28095606
Pubmed	Endogenous endothelin in human coronary vascular function: differential contribution of endothelin receptor types A and B.	EDNRA EDNRB	2.31e-06	3	31	2	17353514
Pubmed	Expression and cellular localisation of renal endothelin-1 and endothelin receptor subtypes in autosomal-dominant polycystic kidney disease.	EDNRA EDNRB	2.31e-06	3	31	2	12629276
Pubmed	ADP-ribosyl cyclase and ryanodine receptors mediate endothelin ETA and ETB receptor-induced renal vasoconstriction in vivo.	EDNRA EDNRB	2.31e-06	3	31	2	18524860
Pubmed	ETB receptor polymorphism is associated with airway obstruction.	EDNRA EDNRB	2.31e-06	3	31	2	17470272
Pubmed	Immunohistochemical assessment of endothelin-1 axis in psoriasis, basal cell carcinoma and squamous cell carcinoma.	EDNRA EDNRB	2.31e-06	3	31	2	25946671
Pubmed	TNFα-induced airway smooth muscle cell proliferation depends on endothelin receptor signaling, GM-CSF and IL-6.	EDNRA EDNRB	2.31e-06	3	31	2	27422754
Pubmed	Genetic association study of endothelin-1 and its receptors EDNRA and EDNRB in migraine with aura.	EDNRA EDNRB	2.31e-06	3	31	2	19558538
Pubmed	A polymorphism in the endothelin-A receptor gene predicts survival in patients with idiopathic dilated cardiomyopathy.	EDNRA EDNRB	2.31e-06	3	31	2	11601839
Pubmed	Gene expression of endothelin receptors in replaced rheumatic mitral stenotic valves.	EDNRA EDNRB	2.31e-06	3	31	2	23515723
Pubmed	Endothelin-1 promotes vascular smooth muscle cell migration across the artery wall: a mechanism contributing to vascular remodelling and intimal hyperplasia in giant-cell arteritis.	EDNRA EDNRB	2.31e-06	3	31	2	28606962
Pubmed	Collecting duct-specific knockout of the endothelin B receptor causes hypertension and sodium retention.	EDNRA EDNRB	2.31e-06	3	31	2	16868309
Pubmed	Association between glaucoma and gene polymorphism of endothelin type A receptor.	EDNRA EDNRB	2.31e-06	3	31	2	15988412
Pubmed	Endothelin-1 inhibits sodium reabsorption by ET(A) and ET(B) receptors in the mouse cortical collecting duct.	EDNRA EDNRB	2.31e-06	3	31	2	23698114
Pubmed	Endothelin axis polymorphisms in patients with scleroderma.	EDNRA EDNRB	2.31e-06	3	31	2	16947775
Pubmed	Expression of the Endothelin-axis in the different histologic subtypes of renal cell carcinoma: a tissue microarray analysis.	EDNRA EDNRB	2.31e-06	3	31	2	17203161
Pubmed	Activation of endothelin-1 receptor signaling pathways is associated with neointima formation, neoangiogenesis and irreversible pulmonary artery hypertension in patients with congenital heart disease.	EDNRA EDNRB	2.31e-06	3	31	2	21498912
Pubmed	Effect of SNP polymorphisms of EDN1, EDNRA, and EDNRB gene on ischemic stroke.	EDNRA EDNRB	2.31e-06	3	31	2	24633486
Pubmed	Endothelin receptor type B counteracts tenascin-C-induced endothelin receptor type A-dependent focal adhesion and actin stress fiber disorganization.	EDNRA EDNRB	2.31e-06	3	31	2	17616673
Pubmed	Overexpression of endothelin-1 and endothelin receptors in the pulmonary arteries of failed Fontan patients.	EDNRA EDNRB	2.31e-06	3	31	2	21356562
Pubmed	Co-localization of the sodium-glucose co-transporter-2 channel (SGLT-2) with endothelin ETA and ETB receptors in human cardiorenal tissue.	EDNRA EDNRB	2.31e-06	3	31	2	38747277
Pubmed	Endothelin-3 induces both human and opossum gallbladder contraction mediated mainly by endothelin-B receptor subtype in vitro.	EDNRA EDNRB	2.31e-06	3	31	2	11982704
Pubmed	Complex expression changes of the placental endothelin system in early and late onset preeclampsia, fetal growth restriction and gestational diabetes.	EDNRA EDNRB	2.31e-06	3	31	2	22580289
Pubmed	Function and survival of dendritic cells depend on endothelin-1 and endothelin receptor autocrine loops.	EDNRA EDNRB	2.31e-06	3	31	2	15213100
Pubmed	Direct action of endothelin-1 on podocytes promotes diabetic glomerulosclerosis.	EDNRA EDNRB	2.31e-06	3	31	2	24722437
Pubmed	Endothelin ETB receptor heterodimerization: beyond the ETA receptor.	EDNRA EDNRB	2.31e-06	3	31	2	18756291
Pubmed	Expression and localization of endothelin-1 and its receptors in the spiral ganglion neurons of mouse.	EDNRA EDNRB	2.31e-06	3	31	2	19370413
Pubmed	Vascular derived endothelin receptor A controls endothelin-induced retinal ganglion cell death.	EDNRA EDNRB	2.31e-06	3	31	2	35429992
Pubmed	Endothelin-1 and its A and B receptors: are they possibly involved in vitiligo?	EDNRA EDNRB	2.31e-06	3	31	2	23683481
Pubmed	Polymorphisms in genes of the endothelin system and cerebral small-vessel disease.	EDNRA EDNRB	2.31e-06	3	31	2	16002759
Pubmed	Endothelin-1 and endothelin receptor gene variants and their association with negative outcomes following aneurysmal subarachnoid hemorrhage.	EDNRA EDNRB	2.31e-06	3	31	2	22997346
Pubmed	Jab1 regulates levels of endothelin type A and B receptors by promoting ubiquitination and degradation.	EDNRA EDNRB	2.31e-06	3	31	2	20034471
Pubmed	Increased expression of endothelin-1 and endothelin receptor A in reflux esophagitis and Barrett's esophagus.	EDNRA EDNRB	2.31e-06	3	31	2	23384184
Pubmed	Increased expression of endothelin-1 and its receptors in varicocele: an immunohistochemical study.	EDNRA EDNRB	2.31e-06	3	31	2	21601190
Pubmed	Increased endothelin and endothelin receptor mRNA expression in polycystic kidneys of cpk mice.	EDNRA EDNRB	4.61e-06	4	31	2	7904485
Pubmed	Smooth muscle specific disruption of the endothelin-A receptor in mice reduces arterial pressure, and vascular reactivity and affects vascular development.	EDNRA EDNRB	4.61e-06	4	31	2	24412386
Pubmed	Increased gene expression of the cardiac endothelin system in obese mice.	EDNRA EDNRB	4.61e-06	4	31	2	25181417
Pubmed	Collecting duct-specific endothelin B receptor knockout increases ENaC activity.	EDNRA EDNRB	4.61e-06	4	31	2	21918182
Pubmed	High Glucose-Induced Cardiomyocyte Damage Involves Interplay between Endothelin ET-1/ETA/ETB Receptor and mTOR Pathway.	EDNRA EDNRB	4.61e-06	4	31	2	36430296
Pubmed	Polymorphism in endothelin-related genes limits exercise-induced decreases in arterial stiffness in older subjects.	EDNRA EDNRB	4.61e-06	4	31	2	16567585
Pubmed	The ligand-receptor interactions of the endothelin systems are mediated by distinct "message" and "address" domains.	EDNRA EDNRB	4.61e-06	4	31	2	7509919
Pubmed	Endothelin-1-, endothelin-A-, and endothelin-B-receptor expression is correlated with vascular endothelial growth factor expression and angiogenesis in breast cancer.	EDNRA EDNRB	4.61e-06	4	31	2	15073116
Pubmed	Endothelin-1 Induces Proteinuria by Heparanase-Mediated Disruption of the Glomerular Glycocalyx.	EDNRA EDNRB	4.61e-06	4	31	2	27026367
Pubmed	Expression of endothelin-converting enzyme, endothelin-1 and endothelin receptors at the site of percutaneous coronary intervention in humans.	EDNRA EDNRB	4.61e-06	4	31	2	16531800
Pubmed	Irreversible and sustained upregulation of endothelin axis during oncogene-associated pancreatic inflammation and cancer.	EDNRA EDNRB	4.61e-06	4	31	2	31923844
Pubmed	Dual genetic pathways of endothelin-mediated intercellular signaling revealed by targeted disruption of endothelin converting enzyme-1 gene.	EDNRA EDNRB	4.61e-06	4	31	2	9449665
Pubmed	Association of single nucleotide polymorphisms in endothelin family genes with the progression of atherosclerosis in patients with essential hypertension.	EDNRA EDNRB	4.61e-06	4	31	2	17525706
Pubmed	Endothelin in the central control of cardiovascular and respiratory functions.	EDNRA EDNRB	7.68e-06	5	31	2	10626068
Pubmed	Characterization of endothelin receptors in the human umbilical artery and vein.	EDNRA EDNRB	7.68e-06	5	31	2	8982507
Pubmed	Endothelin-1 and ETA receptor expression in vascular smooth muscle cells from human placenta: a new ETA receptor messenger ribonucleic acid is generated by alternative splicing of exon 3.	EDNRA EDNRB	7.68e-06	5	31	2	9284755
Pubmed	Deficiency in Six2 during prenatal development is associated with reduced nephron number, chronic renal failure, and hypertension in Br/+ adult mice.	EDNRA EDNRB	7.68e-06	5	31	2	19193724
Pubmed	Low blood pressure in endothelial cell-specific endothelin 1 knockout mice.	EDNRA EDNRB	7.68e-06	5	31	2	20516397
Pubmed	Regulation of retinoblastoma gene expression in a mouse mammary tumor model.	EDNRA EDNRB	7.68e-06	5	31	2	8548579
Pubmed	Gene expression of endothelin isoforms and receptors in endothelin-1 knockout mice.	EDNRA EDNRB	7.68e-06	5	31	2	8587354
Pubmed	Gene expression of vasoactive intestinal contractor/endothelin-2 in ovary, uterus and embryo: comprehensive gene expression profiles of the endothelin ligand-receptor system revealed by semi-quantitative reverse transcription-polymerase chain reaction analysis in adult mouse tissues and during late embryonic development.	EDNRA EDNRB	7.68e-06	5	31	2	10194519
GeneFamily	Endothelin receptors	EDNRA EDNRB	1.84e-06	2	25	2	225
CoexpressionAtlas	DevelopingGonad_e16.5_testes_emap-8444_k-means-cluster#4_top-relative-expression-ranked_100	GATA4 ITGA4 EDNRA	8.17e-06	29	29	3	gudmap_developingGonad_e16.5_testes_100_k4
CoexpressionAtlas	DevelopingGonad_P2_testes_emap-30171_k-means-cluster#1_top-relative-expression-ranked_200	GATA4 ITGA4 EDNRA	1.59e-05	36	29	3	gudmap_developingGonad_P2_testes_200_k1
CoexpressionAtlas	DevelopingGonad_e14.5_ testes_emap-6710_k-means-cluster#2_top-relative-expression-ranked_200	GATA4 ITGA4 EDNRA	1.87e-05	38	29	3	gudmap_developingGonad_e14.5_ testes_200_k2
CoexpressionAtlas	dev gonad_e13.5_M_InterstitFLeydig_MafB_top-relative-expression-ranked_200	GATA4 ITGA4 GUCY1B1 EDNRA	4.46e-05	146	29	4	gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_200
CoexpressionAtlas	DevelopingGonad_e18.5_testes_emap-11164_k-means-cluster#1_top-relative-expression-ranked_200	GATA4 ITGA4 EDNRA	6.05e-05	56	29	3	gudmap_developingGonad_e18.5_testes_200_k1
CoexpressionAtlas	dev gonad_e11.5_M_GonadVasMes_Flk_top-relative-expression-ranked_200	GATA4 GUCY1B1 EDNRA UNC5C	6.68e-05	162	29	4	gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_200
CoexpressionAtlas	DevelopingGonad_e11.5_testes and mesonephros_emap-3226_k-means-cluster#4_top-relative-expression-ranked_1000	GATA4 ITGA4 EDNRA ERI3	7.01e-05	164	29	4	gudmap_developingGonad_e11.5_testes and mesonephros_k4_1000
CoexpressionAtlas	DevelopingGonad_e16.5_testes_emap-8444_k-means-cluster#5_top-relative-expression-ranked_200	GATA4 ITGA4 EDNRA	8.20e-05	62	29	3	gudmap_developingGonad_e16.5_testes_200_k5
CoexpressionAtlas	dev gonad_e12.5_M_InterstitLeydig_MafB_top-relative-expression-ranked_100	GATA4 ITGA4 EDNRA	1.08e-04	68	29	3	gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_100
CoexpressionAtlas	dev gonad_e13.5_M_InterstitTestis_Sma_top-relative-expression-ranked_500	GATA4 ITGA4 GUCY1B1 EDNRA UNC5C	1.17e-04	361	29	5	gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_500
CoexpressionAtlas	dev gonad_e11.5_M_GonadVasMes_Flk_k-means-cluster#3_top-relative-expression-ranked_200	GUCY1B1 EDNRA UNC5C	1.51e-04	76	29	3	gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_k3_200
CoexpressionAtlas	dev gonad_e12.5_M_InterstitTestis_Sma_top-relative-expression-ranked_100	GATA4 ITGA4 EDNRA	1.63e-04	78	29	3	gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_100
CoexpressionAtlas	DevelopingGonad_e16.5_testes_emap-8444_top-relative-expression-ranked_100	GATA4 ITGA4 EDNRA	1.69e-04	79	29	3	gudmap_developingGonad_e16.5_testes_100
CoexpressionAtlas	dev gonad_e13.5_M_InterstitFLeydig_MafB_k-means-cluster#3_top-relative-expression-ranked_200	ITGA4 GUCY1B1 EDNRA	1.89e-04	82	29	3	gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_k3_200
CoexpressionAtlas	DevelopingGonad_e12.5_testes_emap-29069_k-means-cluster#1_top-relative-expression-ranked_500	GATA4 ITGA4 EDNRA	1.89e-04	82	29	3	gudmap_developingGonad_e12.5_testes_k1_500
CoexpressionAtlas	DevelopingGonad_e18.5_testes_emap-11164_top-relative-expression-ranked_100	GATA4 ITGA4 EDNRA	1.96e-04	83	29	3	gudmap_developingGonad_e18.5_testes_100
CoexpressionAtlas	DevelopingGonad_e14.5_ testes_emap-6710_k-means-cluster#5_top-relative-expression-ranked_500	GATA4 ITGA4 EDNRA	3.19e-04	98	29	3	gudmap_developingGonad_e14.5_ testes_500_k5
CoexpressionAtlas	kidney_P0_JuxtaGlom_Ren1_top-relative-expression-ranked_500	ITGA4 TCN2 GUCY1B1 EDNRA EDNRB	3.47e-04	456	29	5	gudmap_kidney_P0_JuxtaGlom_Ren1_500
CoexpressionAtlas	kidney_P1_CapMes_Crym_top-relative-expression-ranked_500	GBE1 ADAT2 EDNRA UNC5C	5.13e-04	276	29	4	gudmap_kidney_P1_CapMes_Crym_500
CoexpressionAtlas	DevelopingGonad_P2_testes_emap-30171_k-means-cluster#1_top-relative-expression-ranked_500	GATA4 ITGA4 EDNRA	5.64e-04	119	29	3	gudmap_developingGonad_P2_testes_500_k1
CoexpressionAtlas	DevelopingGonad_P2_testes_emap-30171_k-means-cluster#2_top-relative-expression-ranked_100	GATA4 EDNRA	5.74e-04	26	29	2	gudmap_developingGonad_P2_testes_100_k2
CoexpressionAtlas	DevelopingGonad_e18.5_testes_emap-11164_k-means-cluster#5_top-relative-expression-ranked_500	GATA4 ITGA4 EDNRA	6.97e-04	128	29	3	gudmap_developingGonad_e18.5_testes_500_k5
CoexpressionAtlas	DevelopingGonad_e16.5_testes_emap-8444_k-means-cluster#2_top-relative-expression-ranked_500	GATA4 ITGA4 EDNRA	7.13e-04	129	29	3	gudmap_developingGonad_e16.5_testes_500_k2
CoexpressionAtlas	dev gonad_e12.5_M_InterstitLeydig_MafB_k-means-cluster#1_top-relative-expression-ranked_1000	ITGA4 GUCY1B1 EDNRA UNC5C	7.93e-04	310	29	4	gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_k1_1000
CoexpressionAtlas	dev gonad_e12.5_M_InterstitLeydig_MafB_top-relative-expression-ranked_200	GATA4 ITGA4 EDNRA	8.67e-04	138	29	3	gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_200
CoexpressionAtlas	kidney_e10.5_UretericTip_HoxB7_k-means-cluster#1_top-relative-expression-ranked_500	ITGA4 EDNRB	9.83e-04	34	29	2	gudmap_kidney_e10.5_UretericTip_HoxB7_k1_500
CoexpressionAtlas	dev gonad_e13.5_M_InterstitTestis_Sma_top-relative-expression-ranked_200	GATA4 ITGA4 EDNRA	1.04e-03	147	29	3	gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_200
CoexpressionAtlas	dev gonad_e13.5_M_InterstitFLeydig_MafB_k-means-cluster#3_top-relative-expression-ranked_1000	ITGA4 GUCY1B1 EDNRA UNC5C	1.07e-03	336	29	4	gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_k3_1000
CoexpressionAtlas	dev gonad_e11.5_F_GonadVasMes_Flk_k-means-cluster#1_top-relative-expression-ranked_200	EDNRA UNC5C	1.16e-03	37	29	2	gudmap_dev gonad_e11.5_F_GonadVasMes_Flk_k1_200
CoexpressionAtlas	dev gonad_e13.5_M_InterstitFLeydig_MafB_k-means-cluster#4_top-relative-expression-ranked_100	ITGA4 EDNRA	1.16e-03	37	29	2	gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_k4_100
CoexpressionAtlas	dev gonad_e12.5_M_InterstitTestis_Sma_top-relative-expression-ranked_200	GATA4 ITGA4 EDNRA	1.17e-03	153	29	3	gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_200
CoexpressionAtlas	kidney_P0_JuxtaGlom_Ren1_top-relative-expression-ranked_1000	GBE1 ITGA4 TCN2 GUCY1B1 EDNRA EDNRB	1.21e-03	905	29	6	gudmap_kidney_P0_JuxtaGlom_Ren1_1000
CoexpressionAtlas	dev gonad_e13.5_M_InterstitTestis_Sma_k-means-cluster#1_top-relative-expression-ranked_500	ITGA4 GUCY1B1 EDNRA	1.24e-03	156	29	3	gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_k1_500
CoexpressionAtlas	DevelopingGonad_e12.5_testes_emap-29069_k-means-cluster#5_top-relative-expression-ranked_1000	GATA4 ITGA4 EDNRA	1.28e-03	158	29	3	gudmap_developingGonad_e12.5_testes_k5_1000
CoexpressionAtlas	DevelopingGonad_e14.5_ testes_emap-6710_top-relative-expression-ranked_200	GATA4 ITGA4 EDNRA	1.30e-03	159	29	3	gudmap_developingGonad_e14.5_ testes_200
CoexpressionAtlas	dev gonad_e13.5_M_InterstitFLeydig_MafB_top-relative-expression-ranked_500	GATA4 ITGA4 GUCY1B1 EDNRA	1.32e-03	356	29	4	gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_500
CoexpressionAtlas	DevelopingGonad_P2_testes_emap-30171_top-relative-expression-ranked_200	GATA4 ITGA4 EDNRA	1.35e-03	161	29	3	gudmap_developingGonad_P2_testes_200
CoexpressionAtlas	dev gonad_e11.5_F_GonadVasMes_Flk_top-relative-expression-ranked_200	GATA4 EDNRA UNC5C	1.35e-03	161	29	3	gudmap_dev gonad_e11.5_F_GonadVasMes_Flk_200
CoexpressionAtlas	DevelopingGonad_e16.5_testes_emap-8444_top-relative-expression-ranked_200	GATA4 ITGA4 EDNRA	1.40e-03	163	29	3	gudmap_developingGonad_e16.5_testes_200
CoexpressionAtlas	DevelopingGonad_e18.5_testes_emap-11164_k-means-cluster#3_top-relative-expression-ranked_100	GATA4 EDNRA	1.43e-03	41	29	2	gudmap_developingGonad_e18.5_testes_100_k3
CoexpressionAtlas	dev gonad_e12.5_M_InterstitLeydig_MafB_top-relative-expression-ranked_500	GATA4 ITGA4 GUCY1B1 EDNRA	1.44e-03	364	29	4	gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_500
CoexpressionAtlas	dev gonad_e12.5_M_InterstitLeydig_MafB_k-means-cluster#2_top-relative-expression-ranked_500	ITGA4 GUCY1B1 EDNRA	1.45e-03	165	29	3	gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_k2_500
CoexpressionAtlas	DevelopingGonad_e18.5_testes_emap-11164_top-relative-expression-ranked_200	GATA4 ITGA4 EDNRA	1.48e-03	166	29	3	gudmap_developingGonad_e18.5_testes_200
CoexpressionAtlas	kidney_P2_CapMes_Crym_top-relative-expression-ranked_1000	GBE1 OR10G2 ADAT2 EDNRA UNC5C	1.55e-03	636	29	5	gudmap_kidney_P2_CapMes_Crym_1000
CoexpressionAtlas	dev gonad_e12.5_M_InterstitTestis_Sma_top-relative-expression-ranked_500	GATA4 ITGA4 EDNRA UNC5C	1.57e-03	373	29	4	gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_500
CoexpressionAtlas	kidney_P0_JuxtaGlom_Ren1_top-relative-expression-ranked_200	ITGA4 EDNRA EDNRB	1.77e-03	177	29	3	gudmap_kidney_P0_JuxtaGlom_Ren1_200
CoexpressionAtlas	kidney_adult_JuxtaGlom_Ren1_Captopr_k-means-cluster#4_top-relative-expression-ranked_1000	ITGA4 GUCY1B1 EDNRA	1.83e-03	179	29	3	gudmap_kidney_adult_JuxtaGlom_Ren1_Captopr_k4_1000
CoexpressionAtlas	DevelopingGonad_e14.5_ testes_emap-6710_k-means-cluster#2_top-relative-expression-ranked_1000	GATA4 ITGA4 EDNRA	1.89e-03	181	29	3	gudmap_developingGonad_e14.5_ testes_1000_k2
CoexpressionAtlas	dev gonad_e13.5_M_InterstitFLeydig_MafB_k-means-cluster#4_top-relative-expression-ranked_500	ITGA4 GUCY1B1 EDNRA	1.92e-03	182	29	3	gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_k4_500
CoexpressionAtlas	dev gonad_e11.5_F_GonMes_Sma_top-relative-expression-ranked_200	GATA4 EDNRA UNC5C	1.95e-03	183	29	3	gudmap_dev gonad_e11.5_F_GonMes_Sma_200
ToppCell	COVID-19-Heart-Pericyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	GUCY1B1 EDNRA EDNRB UNC5C	6.40e-06	181	30	4	33cac65ed1ea5e7bd72250495df4f850b143d5aa
ToppCell	COVID-19-Fibroblasts-Pericytes\|COVID-19 / group, cell type (main and fine annotations)	GUCY1B1 EDNRA EDNRB UNC5C	6.98e-06	185	30	4	4905adaeeffd353e089578e5ea614437dbe794e6
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ITGA4 GUCY1B1 EDNRA UNC5C	7.28e-06	187	30	4	530e4e6d91b5c0d9aa4543caa2b734a1674c5788
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ITGA4 GUCY1B1 EDNRA UNC5C	7.28e-06	187	30	4	ec4b694487cc446999c7b27b119950a4f252c4b3
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ITGA4 GUCY1B1 EDNRA UNC5C	8.08e-06	192	30	4	24e2f15f5767a97eb3b389922bcfd7b13805e1ce
ToppCell	Bronchial-NucSeq-Epithelial-Epi_airway_neuro-secretory-Ionocyte_n_Brush\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PDE12 CUL7 TCN2 FRMPD1	9.12e-06	198	30	4	dd0465b45b02cb8edf0914d19afb52fcaaeb012c
ToppCell	E18.5-Mesenchymal\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PCOLCE2 GUCY1B1 EDNRA EDNRB	9.12e-06	198	30	4	a16aa41eab2e297e56de43c22c355df0f79315da
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-Activated_Alv_Cap\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	ITGA4 GUCY1B1 EDNRB KAT6A	9.49e-06	200	30	4	bcd1cc96197929d6011903803b6f4ccdcf52b4ce
ToppCell	LPS_only-Endothelial-Endothelial-Alv_Cap\|LPS_only / Treatment groups by lineage, cell group, cell type	ITGA4 GUCY1B1 EDNRB KAT6A	9.49e-06	200	30	4	432384faeade8e609154fab3d96c955a8ec868dd
ToppCell	LPS_IL1RA_TNF-Endothelial-Endothelial-Activated_Alv_Cap\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	ITGA4 GUCY1B1 EDNRB KAT6A	9.49e-06	200	30	4	89821a264e872ed53e08e9d3609d5cc5c314503e
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Activated_Alv_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	ITGA4 GUCY1B1 EDNRB KAT6A	9.49e-06	200	30	4	79e51afb57ca38aacebd0298e5e727b55c0cfff9
ToppCell	10x5'-blood-Myeloid_Mac-Intermediate_macrophages\|blood / Manually curated celltypes from each tissue	PCOLCE2 TCN2 EDNRB	1.33e-04	148	30	3	b801f38d249a02c4ceceb242cabbbc88418e5fd1
ToppCell	10x5'-blood-Myeloid_Mac\|blood / Manually curated celltypes from each tissue	PCOLCE2 TCN2 EDNRB	1.33e-04	148	30	3	1ae2d7475e030e2de49940f3287b02953dbf3c65
ToppCell	COVID-19-Heart-Adipocyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	GBE1 PCOLCE2 PNPLA3	1.46e-04	153	30	3	93958bd9c951222ba5b740d1cb83fd5d78a10e1e
ToppCell	Children_(3_yrs)-Mesenchymal-vascular_smooth_muscle_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CAPN14 GUCY1B1 EDNRA	1.61e-04	158	30	3	84c0a215dabf697ada036c2b9592d0c61b5077de
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L3-5_LINC00507_SLN\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PCOLCE2 CNGB1 KCNV2	1.73e-04	162	30	3	b59a0081e285cdf33de56e8b523fe0e446a198f1
ToppCell	facs-Marrow-T_cells-18m-Hematologic-MPP_Fraction_B_+_C\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CNGB1 MFSD3 EDNRB	1.96e-04	169	30	3	2a35846b0e0be0a19a5a04a86cbd72ce65257c8a
ToppCell	Control-Fibroblasts-Pericytes\|Control / group, cell type (main and fine annotations)	GUCY1B1 EDNRA UNC5C	2.03e-04	171	30	3	080003f698f867935c2bfc55d241d3650f45a0ab
ToppCell	Adult-Mesenchymal-vascular_smooth_muscle_cell\|Adult / Lineage, Cell type, age group and donor	GUCY1B1 EDNRA UNC5C	2.07e-04	172	30	3	c62cad0f4212d1e9ea1ec3143ad3c4e06aff0ebf
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_119\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PCOLCE2 FBXO45 EDNRB	2.10e-04	173	30	3	5bb11f9ef17213c9b99fdf92b444f5da3b25fc95
ToppCell	Fetal_29-31_weeks-Mesenchymal-vascular_smooth_muscle_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ITGA4 GUCY1B1 EDNRA	2.14e-04	174	30	3	015d3742d3d79a57413a333f00ef2d380a9848dd
ToppCell	facs-Heart-LV-24m-Mesenchymal-valve_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GUCY1B1 EDNRA EDNRB	2.14e-04	174	30	3	7cd6f9103133f8d7b90f9ff4b3b0b078cf554542
ToppCell	facs-Heart-LV-24m-Mesenchymal-valve_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GUCY1B1 EDNRA EDNRB	2.14e-04	174	30	3	a0a059bb2a64d7011e206db2ebcdf3eb655a925a
ToppCell	COVID-19-Heart-VSMC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	GATA4 EDNRA UNC5C	2.17e-04	175	30	3	1125f0d3a5b2388fa77a820dea0288e824d84a82
ToppCell	tumor_Lymph_Node_/_Brain-Fibroblasts-Pericytes\|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass	GUCY1B1 EDNRA EDNRB	2.21e-04	176	30	3	2015539c58aa0bb118e111ffedd63dd9fe863bb1
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ITGA4 EDNRA UNC5C	2.25e-04	177	30	3	4943d040eee0f9dceaddc7498171281d170e271f
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ITGA4 EDNRA UNC5C	2.25e-04	177	30	3	3f2272b577c862dba8ccfb41184054bbd0ace6f5
ToppCell	Children_(3_yrs)-Mesenchymal-pericyte_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	GUCY1B1 EDNRA UNC5C	2.29e-04	178	30	3	185b44700f06ec58b3c09c80520502166c965fd6
ToppCell	5'-Adult-LymphNode-Endothelial-blood_vessel_EC-arterial_capillary\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GBE1 TCN2 EDNRB	2.29e-04	178	30	3	360d7a987f91d6d721487a921824057ec31a7332
ToppCell	5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.3.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	GUCY1B1 EDNRA UNC5C	2.32e-04	179	30	3	dc6cd46fa652b296ddbc41855f6377946d0a4cdc
ToppCell	E15.5-Mesenchymal-myocytic_cell-vascular_associated_smooth_muscle_cell\|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	ITGA4 GUCY1B1 EDNRA	2.36e-04	180	30	3	38035cf2c6fbc443ea10ca7e942572715ed572da
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Degenerative_Fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	OR8S1 EDNRB UNC5C	2.40e-04	181	30	3	6d1f1ad35778a2a227f966f11f6edd8e89452576
ToppCell	droplet-Lung-LUNG-1m-Mesenchymal-pericyte_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GUCY1B1 EDNRA FRMPD1	2.44e-04	182	30	3	9edaccf1154cec92ca9a28e9b1f9075cfd422bfd
ToppCell	droplet-Lung-LUNG-1m-Mesenchymal-Pericyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GUCY1B1 EDNRA FRMPD1	2.44e-04	182	30	3	aba4c06d5d7618ac21b2695bca8e7a1346a91090
ToppCell	COPD-Stromal-Pericyte\|COPD / Disease state, Lineage and Cell class	GUCY1B1 EDNRA EDNRB	2.52e-04	184	30	3	a56264a22dfc2d3672b20134ab7c3c7c23da5ae1
ToppCell	droplet-Liver-LIVER_HEP-30m-Mesenchymal-hepatic_stellate_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GUCY1B1 EDNRA EDNRB	2.56e-04	185	30	3	40e958511790e84321da5ccf735f9974c06a0263
ToppCell	droplet-Liver-LIVER_HEP-30m-Mesenchymal-hepatic_stellate_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GUCY1B1 EDNRA EDNRB	2.56e-04	185	30	3	5f2eeba80aff145e85cfd81e2890a155406badb9
ToppCell	droplet-Liver-LIVER_HEP-30m-Mesenchymal\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GUCY1B1 EDNRA EDNRB	2.56e-04	185	30	3	f814ec9d4ade717a0109398e9768d0d66f09317b
ToppCell	LV-07._Pericyte\|LV / Chamber and Cluster_Paper	GUCY1B1 EDNRA UNC5C	2.56e-04	185	30	3	acb38eba871ec72f2a8136a33b87d33b8c85465d
ToppCell	droplet-Lung-LUNG-30m-Mesenchymal-Alveolar_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCOLCE2 EDNRA UNC5C	2.60e-04	186	30	3	ca5e9c6531cb5d199e27509bfab1d62e3937177e
ToppCell	droplet-Lung-LUNG-30m-Mesenchymal-fibroblast_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCOLCE2 EDNRA UNC5C	2.60e-04	186	30	3	1ed71b229f40a680071b14f5a7a19706e0fd14b1
ToppCell	RV-07._Pericyte\|RV / Chamber and Cluster_Paper	GUCY1B1 EDNRA UNC5C	2.60e-04	186	30	3	c533b264fbe12bc35467486fc7fbde24ba968fe1
ToppCell	human_hepatoblastoma-Hepatic_Stellate_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	GUCY1B1 EDNRA UNC5C	2.60e-04	186	30	3	cb1fc4b9140666b43415e21c9b434dc9b144e9d0
ToppCell	3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	GUCY1B1 EDNRA UNC5C	2.60e-04	186	30	3	888e85a025bd982d36c910db0f5a3385b1ca3b28
ToppCell	Control-Endothelial-Endothelial-Alv_Cap\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ITGA4 EDNRB KAT6A	2.64e-04	187	30	3	ea9d34bcd3bd1f36745846309ede349773de501a
ToppCell	droplet-Lung-nan-3m-Mesenchymal\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCOLCE2 GUCY1B1 EDNRA	2.64e-04	187	30	3	51f1c6bac3abae1d20aa8ac46642bcdbc02cb0a2
ToppCell	E17.5-Mesenchymal-myocytic_cell-vascular_associated_smooth_muscle_cell\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	ITGA4 GUCY1B1 EDNRA	2.64e-04	187	30	3	0dee138738b65531ff134a125b92234b5d0a653c
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	GUCY1B1 EDNRA UNC5C	2.64e-04	187	30	3	958402fcc78f4c7a7d13d659d776f3817137975f
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	GUCY1B1 EDNRA UNC5C	2.64e-04	187	30	3	48bfdb3504c3fefe5db3abac4b790c369680ab4e
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature3_(17)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	GUCY1B1 EDNRA UNC5C	2.64e-04	187	30	3	a9316e2818217ec5feae9cf8816f7249803caee6
ToppCell	5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.1.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	GUCY1B1 EDNRA UNC5C	2.64e-04	187	30	3	8ee3bf885897efd634c3a0567637142a9f55e693
ToppCell	droplet-Lung-LUNG-30m-Mesenchymal\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCOLCE2 GUCY1B1 EDNRA	2.64e-04	187	30	3	976b74d081b7fba8620768613cc26f9262cd7b16
ToppCell	droplet-Limb_Muscle-nan-21m-Mesenchymal-smooth_muscle_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GUCY1B1 EDNRA EDNRB	2.64e-04	187	30	3	accb8a78b885703a27d4b560f0053f03d82ff3af
ToppCell	E12.5-Mesenchymal\|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	GUCY1B1 EDNRA UNC5C	2.68e-04	188	30	3	9778dadc2bd7ded3a723e717d1c8cd3160e99c6c
ToppCell	Fibroblast-A\|World / shred on cell class and cell subclass (v4)	PCOLCE2 EDNRA UNC5C	2.68e-04	188	30	3	6740bed5fb8f45b6eea17041894b804214c2a4ae
ToppCell	11.5-Airway-Mesenchymal-Pericyte\|Airway / Age, Tissue, Lineage and Cell class	ITGA4 GUCY1B1 EDNRB	2.68e-04	188	30	3	916971d8660fd20f616346953874e89d2cd13e88
ToppCell	Children_(3_yrs)-Mesenchymal-pericyte_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	GUCY1B1 EDNRA UNC5C	2.68e-04	188	30	3	ee151792c7ac9afe820f1a281c6dab383799f358
ToppCell	IPF-Stromal-SMC\|IPF / Disease state, Lineage and Cell class	GUCY1B1 EDNRA EDNRB	2.68e-04	188	30	3	e98b24c0de41285f01f7ac194ff0a1b59fd5c333
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	GUCY1B1 EDNRA UNC5C	2.72e-04	189	30	3	fac5c291a9a87418bb0878c3d624829bdbf1f428
ToppCell	droplet-Lung-LUNG-1m-Mesenchymal-fibroblast_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCOLCE2 EDNRA UNC5C	2.72e-04	189	30	3	32e6d6285b258831b965281224ff2aaeecdcb5f5
ToppCell	Mesenchymal-pericyte_cell\|World / Lineage, Cell type, age group and donor	GUCY1B1 EDNRA UNC5C	2.72e-04	189	30	3	d7ed96add29f219183c802895fbff519b627f635
ToppCell	droplet-Lung-LUNG-1m-Mesenchymal-Alveolar_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCOLCE2 EDNRA UNC5C	2.72e-04	189	30	3	385ef7bbd76c8047aeecf6542377d4213b5da5db
ToppCell	PND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PNPLA3 GUCY1B1 EDNRA	2.72e-04	189	30	3	ca3a04c202afc32aa11d17154066ef7dc6d01405
ToppCell	PND07-28-samps-Mesenchymal-Matrix_fibroblast\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	PCOLCE2 EDNRA UNC5C	2.72e-04	189	30	3	dc5164591dea45b420798b94dda211be03daa70c
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_myocytic-mes_pericyte_(14)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	ITGA4 GUCY1B1 EDNRA	2.77e-04	190	30	3	10125091ad648163777b02e9f0d5e8d7f17d44a5
ToppCell	PND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ITGA4 GUCY1B1 EDNRA	2.77e-04	190	30	3	7e4d80a3a7f83b6a50f1d0fe82fb6c242c39d5b0
ToppCell	P03-Mesenchymal-developing_mesenchymal_cell-mesenchymal_myogenic_precursor_(Axin2+)\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	ITGA4 GUCY1B1 EDNRA	2.77e-04	190	30	3	979b1476fd2692fde977ce56257315fcfc8a01d5
ToppCell	PND07-28-samps-Mesenchymal-Matrix_fibroblast-FB-3\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	PCOLCE2 EDNRA UNC5C	2.77e-04	190	30	3	1196b8ea2c44c7c80f5ee589dd517e6a413f2077
ToppCell	E16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ITGA4 GUCY1B1 EDNRA	2.77e-04	190	30	3	106862ef44fcaa0971c3ba0147d13eb08015ca77
ToppCell	nucseq-Mesenchymal-Myocytic-Myocytic_1-Pericyte\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	GUCY1B1 EDNRA UNC5C	2.77e-04	190	30	3	4eb92aef1ee868f4537483d19014d947b7684612
ToppCell	nucseq-Mesenchymal-Myocytic-Myocytic_1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	GUCY1B1 EDNRA UNC5C	2.77e-04	190	30	3	7be4341e2909101d756f14031c21e705eb45e69a
ToppCell	PND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ITGA4 GUCY1B1 EDNRA	2.77e-04	190	30	3	7fec459cd2ad12c2923a03d098289337c0a4c1d3
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-smooth_muscle_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GUCY1B1 EDNRA EDNRB	2.77e-04	190	30	3	1ab3f19f1ce9f58e5125135704d94655a2e330a0
ToppCell	droplet-Heart-nan-3m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GATA4 PCOLCE2 EDNRA	2.77e-04	190	30	3	96a92212ea3fb35fa3d0da495e504edc61c71c23
ToppCell	Control-Stromal-SMC\|Stromal / Disease state, Lineage and Cell class	GUCY1B1 EDNRA EDNRB	2.81e-04	191	30	3	2da83c493e60ad0278848957645277d76737a188
ToppCell	droplet-Lung-1m-Mesenchymal-fibroblast-alveolar_fibroblast\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PCOLCE2 EDNRA UNC5C	2.81e-04	191	30	3	d04e6292fef189b8d8ed0f4b0c310b2b250fd30e
ToppCell	E16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal\|E16.5-samps / Age Group, Lineage, Cell class and subclass	PCOLCE2 EDNRA UNC5C	2.81e-04	191	30	3	3379d145d34f89150f7b06d1340022cfc6b4a6ce
ToppCell	human_hepatoblastoma-Hepatic_Stellate_cells\|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)	GUCY1B1 EDNRA UNC5C	2.81e-04	191	30	3	78c3c2fdb68c3407f2436f90e1e6a780bbf8b79e
ToppCell	P07-Mesenchymal-mesenchymal_fibroblast\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	PCOLCE2 EDNRA UNC5C	2.81e-04	191	30	3	a05e9a7eb137d804570dd7d8905975d735738767
ToppCell	facs-Heart-LA-24m-Mesenchymal-valve_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GUCY1B1 EDNRA EDNRB	2.81e-04	191	30	3	9c5d88f0d3c834c2419ec3da74652175153ba9df
ToppCell	droplet-Lung-1m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l49\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PCOLCE2 EDNRA UNC5C	2.81e-04	191	30	3	de3e9b704621b26836c2ddc39fa3e840dfb4541b
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	GUCY1B1 EDNRA EDNRB	2.81e-04	191	30	3	7b0d42a877540dbb346a76a62403e0d5d3e07fa6
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	EDNRA EDNRB UNC5C	2.81e-04	191	30	3	1caf726bd07fdca389e678fc16304a6ef1790423
ToppCell	droplet-Lung-1m-Mesenchymal-fibroblast\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PCOLCE2 EDNRA UNC5C	2.81e-04	191	30	3	ce80f65bd24b1c4d2152bf45248449e7a1a97e56
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	EDNRA EDNRB UNC5C	2.81e-04	191	30	3	3d60c46bced2984c27a1fcf2910bc38b31fb0148
ToppCell	P07-Mesenchymal-developing_mesenchymal_cell-mesenchymal_myogenic_precursor_(Axin2+)\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	ITGA4 GUCY1B1 EDNRA	2.81e-04	191	30	3	2ad717b59215ad8d933e9637d363b65d7298e5d4
ToppCell	facs-Heart-LA-24m-Mesenchymal-valve_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GUCY1B1 EDNRA EDNRB	2.81e-04	191	30	3	a7494191a92984e5f53610bbbedd6714e9169e1c
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	GUCY1B1 EDNRA EDNRB	2.81e-04	191	30	3	cd854b9c426924fdc84bf7f411f6dea447143e79
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	EDNRA EDNRB UNC5C	2.85e-04	192	30	3	4022f208eb5db760abd0aac782a25e8ab63efc64
ToppCell	Fibroblast-D_(Pericyte)\|World / shred on cell class and cell subclass (v4)	ITGA4 GUCY1B1 EDNRA	2.85e-04	192	30	3	8c13c351fcc3d88e8c2ffa017e71ff6272cc6fac
ToppCell	P03-Mesenchymal-mesenchymal_fibroblast-alveolar_fibroblast_Wnt2-pa\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	PCOLCE2 EDNRA UNC5C	2.85e-04	192	30	3	2802fae55683345ff94a1ecf73b6fbee4f17481e
ToppCell	droplet-Limb_Muscle-nan-18m-Mesenchymal-smooth_muscle_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GUCY1B1 EDNRA EDNRB	2.85e-04	192	30	3	88472b99970ba0decbf87164fc241a1c77b3b389
ToppCell	E16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ITGA4 GUCY1B1 EDNRA	2.85e-04	192	30	3	430ef714bf2544d32f3fd96a55af010f79aa9be0
ToppCell	droplet-Trachea-nan-3m-Mesenchymal-smooth_muscle_cell_of_trachea\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GUCY1B1 EDNRA EDNRB	2.85e-04	192	30	3	a804cb101c3a5585f72217e1143584b1ca436724
ToppCell	wk_20-22-Mesenchymal-Myofibro_&_SMC-Vascular_SMC_2\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	GUCY1B1 EDNRA EDNRB	2.85e-04	192	30	3	a7d08416f07f29ad920168a3b52ddf992f263bf4
ToppCell	P03-Mesenchymal-developing_mesenchymal_cell\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	ITGA4 GUCY1B1 EDNRA	2.85e-04	192	30	3	063e119c4b58957643908f667e6cfd6f7517fd03
ToppCell	PND14-Mesenchymal-Mesenchymal_structural-Fibroblastic\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PCOLCE2 EDNRA UNC5C	2.85e-04	192	30	3	de9c1536d5aee86f9c62acbc54ca8fa581c00f17
ToppCell	droplet-Lung-30m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l49\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PCOLCE2 EDNRA UNC5C	2.85e-04	192	30	3	ff4b728a55c2550c806c47e9ae3d057c35df8464
ToppCell	PND14-Mesenchymal-Mesenchymal_structural\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PCOLCE2 EDNRA UNC5C	2.85e-04	192	30	3	25492568f9cbe097b7bb1db50d8b817c80ea87d7
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	EDNRA EDNRB UNC5C	2.85e-04	192	30	3	9333aba0d04203ccccad78d82bf6359922f810a7
Drug	Bosentan	EDNRA EDNRB	1.79e-06	2	31	2	DB00559
Drug	PD 145065	EDNRA EDNRB	1.79e-06	2	31	2	ctd:C082887
Drug	TAK 044	EDNRA EDNRB	1.79e-06	2	31	2	ctd:C088196
Drug	LU 224332	EDNRA EDNRB	1.79e-06	2	31	2	ctd:C113044
Drug	L-671,776	EDNRA EDNRB	1.79e-06	2	31	2	CID000122853
Drug	6-bromo-2,3-dihydrobenzofuran	EDNRA EDNRB	1.79e-06	2	31	2	CID011252616
Drug	Sitaxentan	EDNRA EDNRB	1.79e-06	2	31	2	DB06268
Drug	A 182086	EDNRA EDNRB	1.79e-06	2	31	2	ctd:C467893
Drug	tezosentan	EDNRA EDNRB	1.79e-06	2	31	2	ctd:C120582
Drug	spirodihydrobenzofuranlactam VI	EDNRA EDNRB	1.79e-06	2	31	2	CID000469820
Drug	1H-Indene-2-carboxylic acid, 1-(1,3-benzodioxol-5-yl)-3-(2- (carboxymethoxy)-4-methoxyphenyl)-2,3-dihydro-5-propoxy-, (1S,2R,3S)-	EDNRA EDNRB	1.79e-06	2	31	2	ctd:C087551
Drug	J 104132	EDNRA EDNRB	1.79e-06	2	31	2	ctd:C119319
Drug	IRL 1620	EDNRA EDNRB	1.79e-06	2	31	2	ctd:C074308
Drug	PD 156252	EDNRA EDNRB	1.79e-06	2	31	2	ctd:C106950
Drug	enrasentan	EDNRA EDNRB	1.79e-06	2	31	2	ctd:C098288
Drug	WS009A	EDNRA EDNRB	5.38e-06	3	31	2	CID000131948
Drug	Pd164333	EDNRA EDNRB	5.38e-06	3	31	2	CID005311351
Drug	2-ethylacetanilide	EDNRA EDNRB	5.38e-06	3	31	2	CID000036332
Drug	2-nitrobenzoyl chloride	EDNRA EDNRB	5.38e-06	3	31	2	CID000011875
Drug	E106E	EDNRA EDNRB	5.38e-06	3	31	2	CID000026761
Drug	ZD 2574	EDNRA EDNRB	5.38e-06	3	31	2	ctd:C415840
Drug	pyrazolinone	EDNRA EDNRB	5.38e-06	3	31	2	CID000351317
Drug	myriceric acid C	EDNRA EDNRB	5.38e-06	3	31	2	CID005274625
Drug	NSC 90	EDNRA EDNRB	5.38e-06	3	31	2	CID000073811
Drug	bosentan	GATA4 EDNRA EDNRB	9.05e-06	30	31	3	ctd:C086232
Drug	4-phenoxybutyric acid	EDNRA EDNRB	1.07e-05	4	31	2	CID000022741
Drug	sarafotoxins s6	EDNRA EDNRB	1.07e-05	4	31	2	ctd:C057354
Drug	indane-2-carboxylic acid	EDNRA EDNRB	1.07e-05	4	31	2	CID000575777
Drug	pd 151242	EDNRA EDNRB	1.79e-05	5	31	2	CID000132991
Drug	1,5-dihydroxyisoquinoline	EDNRA EDNRB	1.79e-05	5	31	2	ctd:C095653
Drug	Et-(16-21)	EDNRA EDNRB	1.79e-05	5	31	2	CID000129432
Drug	L015040	EDNRA EDNRB	1.79e-05	5	31	2	CID004574540
Drug	butynediol	EDNRA EDNRB	1.79e-05	5	31	2	CID000008066
Drug	2-phenylethenesulfonamide	EDNRA EDNRB	1.79e-05	5	31	2	CID000257501
Drug	Be 18257a	EDNRA EDNRB	1.79e-05	5	31	2	CID000197302
Drug	SB 234551	EDNRA EDNRB	1.79e-05	5	31	2	CID005311425
Drug	R)-3-pyrrolidinecarboxylic acid	EDNRA EDNRB	2.68e-05	6	31	2	CID001501969
Drug	CGS 27830	EDNRA EDNRB	2.68e-05	6	31	2	CID000190809
Drug	Bq 153	EDNRA EDNRB	2.68e-05	6	31	2	CID000196897
Drug	A-192621	EDNRA EDNRB	2.68e-05	6	31	2	CID005310991
Drug	Bq 928	EDNRA EDNRB	2.68e-05	6	31	2	CID000133071
Drug	19-oxo-11-deoxycorticosterone acetate	EDNRA EDNRB	3.75e-05	7	31	2	ctd:C040168
Drug	2,1,3-benzothiadiazole	EDNRA EDNRB	3.75e-05	7	31	2	CID000067502
Drug	dibenzocycloheptatriene	EDNRA EDNRB	3.75e-05	7	31	2	CID000067492
Drug	Be 18257b	EDNRA EDNRB	3.75e-05	7	31	2	CID000197303
Drug	clazosentan	EDNRA EDNRB	5.00e-05	8	31	2	CID006433095
Drug	AC1LCVO8	PNPLA3 KAT6A	5.00e-05	8	31	2	CID000656891
Drug	gallin	ITGA4 EDNRA EDNRB	5.72e-05	55	31	3	CID000191336
Drug	vinyl sulfonamide	EDNRA EDNRB	6.42e-05	9	31	2	CID000520075
Drug	acetamide hydrochloride	EDNRA EDNRB	6.42e-05	9	31	2	CID000517516
Drug	sclerotiorin	EDNRA EDNRB	6.42e-05	9	31	2	CID006436015
Drug	CPU0213	EDNRA EDNRB	8.02e-05	10	31	2	ctd:C513821
Drug	iotrolan	EDNRA EDNRB	8.02e-05	10	31	2	CID000003738
Drug	AC1Q5QI1	EDNRA EDNRB	8.02e-05	10	31	2	CID000186002
Drug	Ro 46-2005	EDNRA EDNRB	8.02e-05	10	31	2	CID000122044
Drug	gamma-methyl-L-leucine	EDNRA EDNRB	8.02e-05	10	31	2	CID000194032
Drug	tetrahydrophthalic anhydride	EDNRA EDNRB	9.79e-05	11	31	2	CID000006810
Drug	C04424	PNPLA3 KAT6A	9.79e-05	11	31	2	CID011953835
Drug	S-nitrosopenicillamine	EDNRA EDNRB	9.79e-05	11	31	2	CID000126366
Drug	Sfflrnp	EDNRA EDNRB	9.79e-05	11	31	2	CID000197436
Drug	Bq 518	EDNRA EDNRB	9.79e-05	11	31	2	CID000443291
Drug	C05118	PNPLA3 KAT6A	1.17e-04	12	31	2	CID000440565
Drug	C05119	PNPLA3 KAT6A	1.17e-04	12	31	2	CID000440566
Drug	AC1L9EUB	PNPLA3 KAT6A	1.39e-04	13	31	2	CID000443527
Drug	atrasentan	EDNRA EDNRB	1.39e-04	13	31	2	ctd:C098644
Drug	R,R-THC	EDNRA EDNRB	1.39e-04	13	31	2	CID000446849
Drug	Phensuximide [86-34-0]; Up 200; 21.2uM; PC3; HT_HG-U133A	PDE12 ITGA4 EDNRA FRMPD1	1.40e-04	196	31	4	5097_UP
Drug	PHA-00745360 [351320-33-7]; Down 200; 10uM; MCF7; HT_HG-U133A	GATA4 CUL7 EDNRA KAT6A	1.40e-04	196	31	4	4381_DN
Drug	Mianserine hydrochloride [21535-47-7]; Down 200; 13.2uM; PC3; HT_HG-U133A	PDE12 GUCY1B1 EDNRA KAT6A	1.45e-04	198	31	4	5786_DN
Drug	Coralyne chloride hydrate [38989-38-7]; Up 200; 9.6uM; MCF7; HT_HG-U133A	PNPLA3 PDE12 CUL7 EDNRB	1.48e-04	199	31	4	2652_UP
Drug	AC1L9EU8	PNPLA3 KAT6A	1.62e-04	14	31	2	CID000443526
Drug	AC1LCVO5	PNPLA3 KAT6A	1.62e-04	14	31	2	CID000656890
Drug	hexyl-beta-d-glucopyranoside	EDNRA EDNRB	1.62e-04	14	31	2	CID000171355
Drug	BMS182874	EDNRA EDNRB	1.86e-04	15	31	2	CID000122272
Drug	A 86929	EDNRA EDNRB	1.86e-04	15	31	2	ctd:C095427
Drug	M 603	EDNRA EDNRB	1.86e-04	15	31	2	CID000162977
Drug	AC1NR4ND	EDNRA EDNRB	2.13e-04	16	31	2	CID005284542
Drug	DuP 532	EDNRA EDNRB	2.13e-04	16	31	2	CID000060770
Drug	phosphoramidon	EDNRA EDNRB	2.13e-04	16	31	2	ctd:C008890
Drug	SB 209670	EDNRA EDNRB	2.13e-04	16	31	2	CID000108002
Drug	thromboxane	TCN2 GUCY1B1 EDNRA EDNRB	2.29e-04	223	31	4	CID000114873
Drug	AC1L9ASI	PNPLA3 KAT6A	2.41e-04	17	31	2	CID000441230
Drug	AC1L3U2Y	EDNRA EDNRB	2.71e-04	18	31	2	CID000122149
Drug	LOE 908	EDNRA EDNRB	2.71e-04	18	31	2	CID000122081
Drug	Pd 145065	EDNRA EDNRB	2.71e-04	18	31	2	CID000123959
Drug	sildenafil	GUCY1B1 EDNRA EDNRB	3.00e-04	96	31	3	CID000005212
Drug	chlorine	EDNRA EDNRB	3.02e-04	19	31	2	CID000024526
Drug	SQ30741	EDNRA EDNRB	3.71e-04	21	31	2	CID005311394
Drug	BQ-788	EDNRA EDNRB	3.71e-04	21	31	2	CID003081333
Drug	L-670,596	EDNRA EDNRB	3.71e-04	21	31	2	CID000129360
Drug	bosentan	GATA4 EDNRA EDNRB	4.01e-04	106	31	3	CID000104865
Drug	Letairis	EDNRA EDNRB	4.86e-04	24	31	2	CID000197712
Drug	tezosentan	EDNRA EDNRB	5.28e-04	25	31	2	CID000151174
Drug	butenolide	EDNRA EDNRB	5.28e-04	25	31	2	CID000010341
Drug	Vitamin B 12	TCN2 GUCY1B1	5.71e-04	26	31	2	ctd:D014805
Drug	IBDU	EDNRA EDNRB	6.17e-04	27	31	2	CID000022478
Drug	Bq 485	EDNRA EDNRB	6.17e-04	27	31	2	CID000123724
Drug	Sch 39370	EDNRA EDNRB	6.17e-04	27	31	2	CID000121872
Drug	benidipine	EDNRA EDNRB	6.17e-04	27	31	2	ctd:C061004
Drug	Dinoprost	GATA4 EDNRA EDNRB	6.19e-04	123	31	3	ctd:D015237
Disease	Eosinophilic esophagitis	TRIM8 CAPN14	5.59e-06	4	29	2	C0341106
Disease	Diaphragmatic Hernia	GATA4 EDNRA EDNRB	8.87e-06	41	29	3	C0019284
Disease	myocardial infarction (implicated_via_orthology)	GATA4 EDNRA EDNRB	3.75e-05	66	29	3	DOID:5844 (implicated_via_orthology)
Disease	portal hypertension (implicated_via_orthology)	EDNRA EDNRB	1.58e-04	19	29	2	DOID:10762 (implicated_via_orthology)
Disease	myocardial infarction	GUCY1B1 ANKUB1 EDNRA UNC5C	3.66e-04	350	29	4	EFO_0000612
Disease	pulmonary hypertension (implicated_via_orthology)	EDNRA EDNRB	1.29e-03	54	29	2	DOID:6432 (implicated_via_orthology)
Disease	low density lipoprotein particle size measurement	GATA4 PNPLA3	1.49e-03	58	29	2	EFO_0008593
Disease	polycystic ovary syndrome	GATA4 UNC5C	1.59e-03	60	29	2	EFO_0000660
Disease	pulmonary hypertension (is_marker_for)	EDNRA EDNRB	1.81e-03	64	29	2	DOID:6432 (is_marker_for)

Protein segments in the cluster

Peptide	Gene	Start	Entry
KVMLPGQCQYLGLPV	ERI3	251	O43414
LMKIPLVVYGCQNER	ADAT2	116	Q7Z6V5
LLRIIYQNKCMRNGP	EDNRA	101	P25101
IYKNKCMRNGPNILI	EDNRB	126	P24530
VCQLMLIRYGGPRLQ	CAPN14	626	A8MX76
PKGGYIRLIQMAVAL	PDE12	461	Q6L8Q7
GGYMSKICNLLPIRI	PNPLA3	336	Q9NST1
YRKLITNILGGCIQM	CUL7	786	Q14999
ISCLRLKGQMIYLPE	GUCY1B1	301	Q02153
QCPLLRRGLNYIIMG	PCOLCE2	366	Q9UKZ9
MRGKLLPLAGLYLVQ	MFSD3	1	Q96ES6
CIMILPQYQRKGYGR	KAT6A	646	Q92794
CGLYHKMNGINRPLI	GATA4	241	P43694
RIKGLGYNCIQLMAI	GBE1	226	Q04446
KRAPMQCQGYVALLG	FBXO45	176	P0C2W1
LLCMPNVLKLYLENG	FRMPD1	176	Q5SYB0
MLLLCLGVPTGRPYN	ITGA4	21	P13612
LRLKPQLLQGVYAMG	DDX19A	96	Q9NUU7
ICQPLRYPVLMNGRL	OR10G2	131	Q8NGC3
RYNVIMNPKLCGLLL	OR7G3	131	Q8NG95
GIILNGMPISILYNK	KCNV2	481	Q8TDN2
ICRPLLYGQIMGKQL	OR8S1	126	Q8NH09
CQGKPSMGQLALYLL	TCN2	96	P20062
ADMYLLPGLKRLCGR	ABTB1	356	Q969K4
LMGCLLGQKLKVQRY	ANKUB1	166	A6NFN9
GVNPLLRLPRCLKYM	CNGB1	756	Q14028
LPKLQYNKNLGMVCR	WASHC5	1051	Q12768
MVQGECLLKYQLRPR	ELAC2	416	Q9BQ52
MGPQLLGYVVLCLLG	TRBV27	1	A0A0K0K1C4
MLPQYGGRKILVCSV	TRIM8	456	Q9BZR9
RCGLGLGYLLQMLVL	UNC5C	11	O95185