Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	ubiquitin-like protein transferase activity	RGPD2 RANBP2 RGPD8 CUL9 TRIM64 MDM4 PIAS1 TRIM64C TRIM64B UBE4A RNF220 RNF167 RNF4 BRCA1 OBI1	3.97e-07	512	119	15	GO:0019787
GeneOntologyMolecularFunction	aminoacyltransferase activity	RGPD2 RANBP2 RGPD8 CUL9 TRIM64 MDM4 PIAS1 TRIM64C TRIM64B UBE4A RNF220 RNF167 RNF4 BRCA1 OBI1	6.44e-07	532	119	15	GO:0016755
GeneOntologyMolecularFunction	acyltransferase activity	RGPD2 RANBP2 RGPD8 CUL9 TRIM64 MDM4 PIAS1 ZDHHC4 TRIM64C TRIM64B UBE4A RNF220 RNF167 RNF4 BRCA1 KAT6B OBI1	3.46e-06	775	119	17	GO:0016746
GeneOntologyMolecularFunction	ubiquitin-like protein ligase activity	RGPD2 RANBP2 RGPD8 CUL9 TRIM64 PIAS1 TRIM64C TRIM64B UBE4A RNF220 RNF167 RNF4	4.64e-06	398	119	12	GO:0061659
GeneOntologyMolecularFunction	SUMO ligase activity	RGPD2 RANBP2 RGPD8 PIAS1	5.40e-06	20	119	4	GO:0061665
GeneOntologyMolecularFunction	zinc ion binding	PAPPA2 USP49 PGLYRP4 CUL9 TRIM64 MDM4 KLF4 PIAS1 TRIM64C TRIM64B RNF167 RNF4 BRCA1 TET1 PAPPA EEA1 SEC23B	2.14e-05	891	119	17	GO:0008270
GeneOntologyMolecularFunction	SUMO transferase activity	RGPD2 RANBP2 RGPD8 PIAS1	6.10e-05	36	119	4	GO:0019789
GeneOntologyMolecularFunction	iron-responsive element binding	IREB2 FECH	1.05e-04	3	119	2	GO:0030350
GeneOntologyMolecularFunction	ubiquitin-protein transferase activity	CUL9 TRIM64 MDM4 TRIM64C TRIM64B UBE4A RNF220 RNF167 RNF4 BRCA1 OBI1	1.24e-04	473	119	11	GO:0004842
GeneOntologyMolecularFunction	enzyme activator activity	RGPD2 RANBP2 SFRP2 PDE8A RGPD8 ALS2 ARHGAP39 LCK ANKRD27 BMP2 SEC23B RGPD5 PCOLCE	1.48e-04	656	119	13	GO:0008047
GeneOntologyMolecularFunction	non-membrane spanning protein tyrosine kinase activity	LCK MELK JAK1 JAK3	1.61e-04	46	119	4	GO:0004715
GeneOntologyMolecularFunction	transition metal ion binding	PAPPA2 USP49 PGLYRP4 CUL9 TRIM64 MDM4 KLF4 PIAS1 TRIM64C TRIM64B RNF167 RNF4 BRCA1 TET1 FECH PAPPA EEA1 SEC23B	2.34e-04	1189	119	18	GO:0046914
GeneOntologyMolecularFunction	enzyme regulator activity	RGPD2 RANBP2 SFRP2 PDE8A RGPD8 SPOCK1 PPP1R3B MCF2L2 ALS2 HMGCR ARHGAP39 LCK KLF4 ANKRD27 BMP2 CST3 SEC23B RAC2 RGPD5 PCOLCE	2.61e-04	1418	119	20	GO:0030234
GeneOntologyMolecularFunction	GTPase activator activity	RGPD2 RANBP2 RGPD8 ALS2 ARHGAP39 ANKRD27 SEC23B RGPD5	2.70e-04	279	119	8	GO:0005096
GeneOntologyMolecularFunction	nucleoside-triphosphatase regulator activity	RGPD2 RANBP2 RGPD8 MCF2L2 ALS2 HMGCR ARHGAP39 ANKRD27 SEC23B RGPD5	9.17e-04	507	119	10	GO:0060589
GeneOntologyMolecularFunction	GTPase regulator activity	RGPD2 RANBP2 RGPD8 MCF2L2 ALS2 HMGCR ARHGAP39 ANKRD27 SEC23B RGPD5	9.17e-04	507	119	10	GO:0030695
GeneOntologyMolecularFunction	molecular function activator activity	RGPD2 RANBP2 SFRP2 PDE8A RGPD8 ALS2 ARHGAP39 LCK ANKRD27 CCN5 BMP2 BMP5 GRPEL1 FGF11 SEC23B RGPD5 PCOLCE	1.02e-03	1233	119	17	GO:0140677
GeneOntologyMolecularFunction	growth hormone receptor binding	JAK1 JAK3	1.54e-03	10	119	2	GO:0005131
GeneOntologyMolecularFunction	protein phosphatase binding	PPP1R3B HMGCR LCK JAK1 JAK3 ROS1	1.63e-03	210	119	6	GO:0019903
GeneOntologyMolecularFunction	ubiquitin protein ligase activity	CUL9 TRIM64 TRIM64C TRIM64B UBE4A RNF220 RNF167 RNF4	1.75e-03	372	119	8	GO:0061630
GeneOntologyMolecularFunction	protein tyrosine kinase activity	LCK MELK JAK1 JAK3 ROS1	1.77e-03	145	119	5	GO:0004713
GeneOntologyMolecularFunction	BMP receptor binding	BMP2 BMP5	2.63e-03	13	119	2	GO:0070700
GeneOntologyMolecularFunction	small GTPase binding	RGPD2 RANBP2 RGPD8 RHOBTB3 ALS2 ANKRD27 IPO13	3.14e-03	321	119	7	GO:0031267
GeneOntologyMolecularFunction	peptidyl-prolyl cis-trans isomerase activity	RGPD2 RANBP2 RGPD8	3.30e-03	50	119	3	GO:0003755
GeneOntologyBiologicalProcess	NLS-bearing protein import into nucleus	RGPD2 RANBP2 RGPD8 RGPD5	4.44e-06	20	117	4	GO:0006607
GeneOntologyBiologicalProcess	positive regulation of glucokinase activity	RGPD2 RANBP2 RGPD8	1.46e-05	9	117	3	GO:0033133
GeneOntologyBiologicalProcess	positive regulation of hexokinase activity	RGPD2 RANBP2 RGPD8	2.07e-05	10	117	3	GO:1903301
GeneOntologyBiologicalProcess	positive regulation of Wnt signaling pathway	SFRP2 RSPO3 BMP2 RNF220 SALL1 TMEM9 GPC5	3.32e-05	158	117	7	GO:0030177
GeneOntologyBiologicalProcess	protein modification by small protein conjugation	RANBP2 CUL9 TRIM64 MDM4 ZC4H2 PIAS1 TRIM64C TRIM64B UBE4A RNF220 RNF167 RNF4 BRCA1 RAB40AL UBA6 OBI1	4.46e-05	893	117	16	GO:0032446
GeneOntologyBiologicalProcess	regulation of glucokinase activity	RGPD2 RANBP2 RGPD8	4.88e-05	13	117	3	GO:0033131
GeneOntologyBiologicalProcess	chordate embryonic development	MYF5 GGNBP2 SFRP2 SIN3A KLF4 AXIN2 RSPO3 BMP2 BMP5 RNF220 SALL1 BRCA1 TET1 ANKRD11 C6 NOTCH2	5.29e-05	906	117	16	GO:0043009
GeneOntologyBiologicalProcess	protein modification by small protein conjugation or removal	USP49 RANBP2 CUL9 TRIM64 MDM4 ZC4H2 PIAS1 TRIM64C TRIM64B UBE4A RNF220 RNF167 RNF4 BRCA1 RAB40AL UBA6 OBI1	5.44e-05	1009	117	17	GO:0070647
GeneOntologyBiologicalProcess	regulation of hexokinase activity	RGPD2 RANBP2 RGPD8	6.19e-05	14	117	3	GO:1903299
GeneOntologyBiologicalProcess	embryo development ending in birth or egg hatching	MYF5 GGNBP2 SFRP2 SIN3A KLF4 AXIN2 RSPO3 BMP2 BMP5 RNF220 SALL1 BRCA1 TET1 ANKRD11 C6 NOTCH2	7.11e-05	929	117	16	GO:0009792
GeneOntologyBiologicalProcess	post-translational protein modification	USP49 RANBP2 CUL9 TRIM64 MDM4 ZC4H2 PIAS1 TRIM64C TRIM64B UBE4A RNF220 RNF167 RNF4 BRCA1 RAB40AL UBA6 OBI1	1.17e-04	1074	117	17	GO:0043687
GeneOntologyBiologicalProcess	regulation of kinase activity	RGPD2 RANBP2 GGNBP2 SFRP2 RGPD8 ALS2 HMGCR AXIN2 CEMIP BMP2 PDE5A ROS1 NOTCH2	1.41e-04	686	117	13	GO:0043549
GeneOntologyBiologicalProcess	import into nucleus	RGPD2 RANBP2 RGPD8 CDAN1 BRCA1 IPO13 RGPD5	1.51e-04	201	117	7	GO:0051170
GeneOntologyBiologicalProcess	negative regulation of cortisol biosynthetic process	BMP2 BMP5	1.90e-04	4	117	2	GO:2000065
GeneOntologyBiologicalProcess	negative regulation of aldosterone metabolic process	BMP2 BMP5	1.90e-04	4	117	2	GO:0032345
GeneOntologyBiologicalProcess	negative regulation of aldosterone biosynthetic process	BMP2 BMP5	1.90e-04	4	117	2	GO:0032348
GeneOntologyBiologicalProcess	regulation of transferase activity	RGPD2 RANBP2 GGNBP2 SFRP2 RGPD8 ALS2 HMGCR KLF4 AXIN2 CEMIP BMP2 PDE5A ROS1 NOTCH2	2.01e-04	810	117	14	GO:0051338
GeneOntologyBiologicalProcess	protein ubiquitination	CUL9 TRIM64 MDM4 ZC4H2 TRIM64C TRIM64B UBE4A RNF220 RNF167 RNF4 BRCA1 RAB40AL UBA6 OBI1	2.04e-04	811	117	14	GO:0016567
GeneOntologyBiologicalProcess	protein localization to nucleus	RGPD2 RANBP2 RGPD8 SIN3A NMD3 JAK1 BRCA1 IPO13 RGPD5	2.24e-04	362	117	9	GO:0034504
GeneOntologyBiologicalProcess	noradrenergic neuron development	ZC4H2 RNF220	3.15e-04	5	117	2	GO:0003358
GeneOntologyBiologicalProcess	negative regulation of glucocorticoid metabolic process	BMP2 BMP5	3.15e-04	5	117	2	GO:0031944
GeneOntologyBiologicalProcess	negative regulation of glucocorticoid biosynthetic process	BMP2 BMP5	3.15e-04	5	117	2	GO:0031947
GeneOntologyBiologicalProcess	atrioventricular canal morphogenesis	BMP2 NFIX	3.15e-04	5	117	2	GO:1905222
GeneOntologyBiologicalProcess	heart valve morphogenesis	MDM4 AXIN2 BMP2 NOTCH2	4.53e-04	63	117	4	GO:0003179
GeneOntologyBiologicalProcess	negative regulation of steroid hormone biosynthetic process	BMP2 BMP5	4.71e-04	6	117	2	GO:0090032
GeneOntologyBiologicalProcess	negative regulation of vesicle fusion	ANKRD27 SYT4	4.71e-04	6	117	2	GO:0031339
GeneOntologyBiologicalProcess	positive regulation of transferase activity	RGPD2 RANBP2 RGPD8 ALS2 KLF4 AXIN2 CEMIP PDE5A ROS1 NOTCH2	4.82e-04	490	117	10	GO:0051347
GeneOntologyBiologicalProcess	positive regulation of phosphorylation	RGPD2 RANBP2 SFRP2 RGPD8 ALS2 LCK CDCA8 AXIN2 CEMIP BMP2 PDE5A ROS1 NOTCH2	4.85e-04	780	117	13	GO:0042327
GeneOntologyBiologicalProcess	positive regulation of kinase activity	RGPD2 RANBP2 RGPD8 ALS2 AXIN2 CEMIP PDE5A ROS1 NOTCH2	5.07e-04	405	117	9	GO:0033674
GeneOntologyBiologicalProcess	atrioventricular valve morphogenesis	MDM4 AXIN2 BMP2	5.25e-04	28	117	3	GO:0003181
GeneOntologyCellularComponent	cytoplasmic periphery of the nuclear pore complex	RGPD2 RANBP2 RGPD8	9.87e-06	8	119	3	GO:1990723
GeneOntologyCellularComponent	nuclear pore cytoplasmic filaments	RGPD2 RANBP2 RGPD8	2.10e-05	10	119	3	GO:0044614
GeneOntologyCellularComponent	annulate lamellae	RGPD2 RANBP2 RGPD8	6.25e-05	14	119	3	GO:0005642
GeneOntologyCellularComponent	nuclear pore nuclear basket	RGPD2 RANBP2 RGPD8	1.38e-04	18	119	3	GO:0044615
GeneOntologyCellularComponent	nuclear inclusion body	RGPD2 RANBP2 RGPD8	1.91e-04	20	119	3	GO:0042405
GeneOntologyCellularComponent	SUMO ligase complex	RGPD2 RANBP2 RGPD8	2.22e-04	21	119	3	GO:0106068
GeneOntologyCellularComponent	nuclear pore	RGPD2 RANBP2 RGPD8 NPIPA1 RGPD5	2.82e-04	101	119	5	GO:0005643
GeneOntologyCellularComponent	nuclear envelope	RGPD2 AEN RANBP2 RGPD8 NPIPA1 CEMIP DST RAB40AL CST3 RAC2 RGPD5	3.59e-04	560	119	11	GO:0005635
MousePheno	limbs/digits/tail phenotype	SECISBP2L PAPPA2 SFRP2 PGLYRP4 RHOBTB3 MDM4 ANKRD27 AXIN2 CEMIP JAK1 UBE4A BMP2 BMP5 C9orf43 DST SALL1 BRCA1 MITF PAPPA PDE5A KAT6B NOTCH2 PCOLCE	1.07e-06	1258	85	23	MP:0005371
MousePheno	abnormal appendicular skeleton morphology	PAPPA2 MYF5 SFRP2 GLS2 RHOBTB3 ANKRD27 CEMIP ADAMTS10 UBE4A BMP5 C9orf43 SALL1 NFIX MITF PAPPA KAT6B NOTCH2 PCOLCE	5.69e-06	896	85	18	MP:0009250
MousePheno	abnormal long bone morphology	PAPPA2 SFRP2 ANKRD27 CEMIP ADAMTS10 UBE4A BMP5 C9orf43 SALL1 NFIX MITF PAPPA KAT6B NOTCH2 PCOLCE	1.21e-05	676	85	15	MP:0003723
MousePheno	decreased length of long bones	PAPPA2 SFRP2 ANKRD27 CEMIP ADAMTS10 UBE4A BMP5 C9orf43 MITF PAPPA NOTCH2	3.58e-05	409	85	11	MP:0004686
MousePheno	abnormal limb bone morphology	PAPPA2 SFRP2 RHOBTB3 ANKRD27 CEMIP UBE4A BMP5 C9orf43 SALL1 PAPPA KAT6B NOTCH2 PCOLCE	5.06e-05	587	85	13	MP:0002115
MousePheno	elevated level of mitotic sister chromatid exchange	RGPD2 RANBP2 RGPD8	1.15e-04	16	85	3	MP:0003701
MousePheno	abnormal limb morphology	SECISBP2L PAPPA2 SFRP2 PGLYRP4 RHOBTB3 MDM4 ANKRD27 AXIN2 CEMIP UBE4A BMP5 C9orf43 SALL1 PAPPA KAT6B NOTCH2 PCOLCE	1.27e-04	1028	85	17	MP:0002109
MousePheno	abnormal limb long bone morphology	PAPPA2 SFRP2 ANKRD27 CEMIP UBE4A BMP5 C9orf43 SALL1 PAPPA KAT6B NOTCH2 PCOLCE	1.58e-04	568	85	12	MP:0011504
MousePheno	abnormal tail morphology	PAPPA2 SFRP2 AXIN2 JAK1 BMP2 BMP5 DST BRCA1 MITF PDE5A	1.61e-04	403	85	10	MP:0002111
MousePheno	abnormal ventral interneuron 1 morphology	ZC4H2 RNF220	2.18e-04	4	85	2	MP:0021103
Domain	Ran_BP1	RGPD2 RANBP2 RGPD8 RGPD5	7.97e-07	12	121	4	PF00638
Domain	RANBD1	RGPD2 RANBP2 RGPD8 RGPD5	7.97e-07	12	121	4	PS50196
Domain	RanBD	RGPD2 RANBP2 RGPD8 RGPD5	1.15e-06	13	121	4	SM00160
Domain	Ran_bind_dom	RGPD2 RANBP2 RGPD8 RGPD5	1.15e-06	13	121	4	IPR000156
Domain	NPIP	NPIPA1 NPIPA7 NPIPA5 NPIPA3	1.60e-06	14	121	4	IPR009443
Domain	TSP_1	ADAMTSL1 THSD7A ADAMTS10 CCN5 RSPO3 C6	3.28e-06	63	121	6	PF00090
Domain	TSP1	ADAMTSL1 THSD7A ADAMTS10 CCN5 RSPO3 C6	3.95e-06	65	121	6	SM00209
Domain	TSP1_rpt	ADAMTSL1 THSD7A ADAMTS10 CCN5 RSPO3 C6	3.95e-06	65	121	6	IPR000884
Domain	TSP1	ADAMTSL1 THSD7A ADAMTS10 CCN5 RSPO3 C6	3.95e-06	65	121	6	PS50092
Domain	Notch_dom	PAPPA2 PAPPA NOTCH2	9.11e-06	7	121	3	IPR000800
Domain	Notch	PAPPA2 PAPPA NOTCH2	9.11e-06	7	121	3	PF00066
Domain	NL	PAPPA2 PAPPA NOTCH2	9.11e-06	7	121	3	SM00004
Domain	-	USP49 TRIM64 MDM4 TRIM64B UBE4A RNF220 RNF167 RNF4 BRCA1 EEA1 KAT6B OBI1	3.53e-05	449	121	12	3.30.40.10
Domain	Peptidase_M43	PAPPA2 PAPPA	4.16e-05	2	121	2	IPR008754
Domain	Peptidase_M43	PAPPA2 PAPPA	4.16e-05	2	121	2	PF05572
Domain	Grip	RGPD2 RGPD8 RGPD5	4.21e-05	11	121	3	SM00755
Domain	GRIP	RGPD2 RGPD8 RGPD5	4.21e-05	11	121	3	PF01465
Domain	Znf_RING/FYVE/PHD	USP49 TRIM64 MDM4 TRIM64B UBE4A RNF220 RNF167 RNF4 BRCA1 EEA1 KAT6B OBI1	4.37e-05	459	121	12	IPR013083
Domain	GRIP_dom	RGPD2 RGPD8 RGPD5	5.59e-05	12	121	3	IPR000237
Domain	GRIP	RGPD2 RGPD8 RGPD5	5.59e-05	12	121	3	PS50913
Domain	ZF_RING_1	CUL9 TRIM64 MDM4 TRIM64B RNF220 RNF167 RNF4 BRCA1 OBI1	1.18e-04	291	121	9	PS00518
Domain	Myxo_disulph_rpt	PAPPA2 PAPPA	1.24e-04	3	121	2	IPR011936
Domain	ZF_RING_2	CUL9 TRIM64 MDM4 TRIM64B RNF220 RNF167 RNF4 BRCA1 OBI1	1.41e-04	298	121	9	PS50089
Domain	RING	CUL9 TRIM64 MDM4 TRIM64B RNF220 RNF167 RNF4 BRCA1 OBI1	1.68e-04	305	121	9	SM00184
Domain	LamGL	PAPPA2 PAPPA	2.48e-04	4	121	2	SM00560
Domain	LamG-like	PAPPA2 PAPPA	2.48e-04	4	121	2	IPR006558
Domain	Tyr_kinase_non-rcpt_Jak/Tyk2	JAK1 JAK3	2.48e-04	4	121	2	IPR016251
Domain	Znf_RING	CUL9 TRIM64 MDM4 TRIM64B RNF220 RNF167 RNF4 BRCA1 OBI1	2.75e-04	326	121	9	IPR001841
Domain	Sushi	PAPPA2 MASP1 PAPPA C6	3.57e-04	52	121	4	PF00084
Domain	CCP	PAPPA2 MASP1 PAPPA C6	4.13e-04	54	121	4	SM00032
Domain	SUSHI	PAPPA2 MASP1 PAPPA C6	4.75e-04	56	121	4	PS50923
Domain	Sushi_SCR_CCP_dom	PAPPA2 MASP1 PAPPA C6	5.08e-04	57	121	4	IPR000436
Domain	EGF_3	MASP1 ATRNL1 ADGRE3 C6 NAGPA TNR NOTCH2	8.56e-04	235	121	7	PS50026
Domain	Rab_bind	RGPD2 RGPD8	8.56e-04	7	121	2	PF16704
Domain	GCC2_Rab_bind	RGPD2 RGPD8	8.56e-04	7	121	2	IPR032023
Domain	EGF-like_dom	MASP1 ATRNL1 ADGRE3 C6 NAGPA TNR NOTCH2	1.20e-03	249	121	7	IPR000742
Domain	Kazal_2	SPOCK1 SLCO4A1 C6	1.62e-03	36	121	3	PF07648
Domain	VPS9	ALS2 ANKRD27	1.81e-03	10	121	2	PS51205
Domain	VPS9	ALS2 ANKRD27	1.81e-03	10	121	2	PF02204
Domain	VPS9	ALS2 ANKRD27	1.81e-03	10	121	2	IPR003123
Domain	-	RGPD2 RGPD8	1.81e-03	10	121	2	1.10.220.60
Domain	Tyr_kinase_cat_dom	LCK JAK1 JAK3 ROS1	2.57e-03	88	121	4	IPR020635
Domain	TyrKc	LCK JAK1 JAK3 ROS1	2.57e-03	88	121	4	SM00219
Domain	SSD	HMGCR DISP2	3.10e-03	13	121	2	IPR000731
Domain	SSD	HMGCR DISP2	3.10e-03	13	121	2	PS50156
Domain	Linker_histone	H1-9P KAT6B	3.10e-03	13	121	2	PF00538
Domain	KAZAL	SPOCK1 SLCO4A1 C6	3.29e-03	46	121	3	SM00280
Domain	zf-C3HC4	TRIM64 TRIM64B RNF167 RNF4 BRCA1 OBI1	3.33e-03	223	121	6	PF00097
Domain	Histone_H1/H5_H15	H1-9P KAT6B	3.60e-03	14	121	2	IPR005818
Domain	EXOIII	AEN REXO5	3.60e-03	14	121	2	SM00479
Domain	PLAC	ADAMTSL1 ADAMTS10	3.60e-03	14	121	2	PF08686
Domain	Exonuclease_RNaseT/DNA_pol3	AEN REXO5	3.60e-03	14	121	2	IPR013520
Domain	RNase_T	AEN REXO5	3.60e-03	14	121	2	PF00929
Domain	PROTEIN_KINASE_TYR	LCK JAK1 JAK3 ROS1	3.65e-03	97	121	4	PS00109
Domain	Tyr_kinase_AS	LCK JAK1 JAK3 ROS1	3.65e-03	97	121	4	IPR008266
Domain	CUB	MASP1 ATRNL1 PCOLCE	3.93e-03	49	121	3	PF00431
Domain	KAZAL_2	SPOCK1 SLCO4A1 C6	4.16e-03	50	121	3	PS51465
Domain	CUB	MASP1 ATRNL1 PCOLCE	4.16e-03	50	121	3	SM00042
Domain	Znf_RING_CS	CUL9 TRIM64 TRIM64B RNF4 BRCA1	4.20e-03	163	121	5	IPR017907
Domain	EGF	RSPO3 ATRNL1 ADGRE3 NAGPA TNR NOTCH2	4.30e-03	235	121	6	SM00181
Domain	Kazal_dom	SPOCK1 SLCO4A1 C6	4.40e-03	51	121	3	IPR002350
Domain	-	MASP1 ATRNL1 PCOLCE	4.65e-03	52	121	3	2.60.120.290
Domain	CUB	MASP1 ATRNL1 PCOLCE	4.91e-03	53	121	3	PS01180
Domain	Znf_C3HC4_RING-type	TRIM64 TRIM64B RNF167 RNF4 BRCA1	5.26e-03	172	121	5	IPR018957
Domain	C345C	SFRP2 PCOLCE	5.31e-03	17	121	2	SM00643
Domain	CUB_dom	MASP1 ATRNL1 PCOLCE	6.02e-03	57	121	3	IPR000859
Domain	EGF_1	MASP1 ATRNL1 C6 NAGPA TNR NOTCH2	6.36e-03	255	121	6	PS00022
Pathway	BIOCARTA_RANBP2_PATHWAY	RGPD2 RANBP2 RGPD8 PIAS1	2.91e-06	18	81	4	MM1549
Pathway	REACTOME_SUMOYLATION	RGPD2 RANBP2 RGPD8 SIN3A CDCA8 PIAS1 BRCA1 MITF	5.53e-06	169	81	8	MM14919
Pathway	REACTOME_INTERLEUKIN_2_SIGNALING	LCK JAK1 JAK3	3.87e-05	12	81	3	M27893
Pathway	BIOCARTA_IL7_PATHWAY	LCK JAK1 JAK3	9.70e-05	16	81	3	M1296
Pathway	BIOCARTA_IL7_PATHWAY	LCK JAK1 JAK3	9.70e-05	16	81	3	MM1420
Pathway	REACTOME_SUMOYLATION_OF_DNA_DAMAGE_RESPONSE_AND_REPAIR_PROTEINS	RGPD2 RANBP2 RGPD8 PIAS1 BRCA1	1.20e-04	84	81	5	MM14929
Pathway	REACTOME_SUMOYLATION_OF_UBIQUITINYLATION_PROTEINS	RGPD2 RANBP2 RGPD8 PIAS1	1.50e-04	47	81	4	MM14939
Pathway	REACTOME_SUMOYLATION_OF_DNA_REPLICATION_PROTEINS	RGPD2 RANBP2 RGPD8 CDCA8	2.06e-04	51	81	4	MM15151
Pathway	BIOCARTA_IL2_PATHWAY	LCK JAK1 JAK3	2.60e-04	22	81	3	M7747
Pathway	BIOCARTA_IL2_PATHWAY	LCK JAK1 JAK3	2.98e-04	23	81	3	MM1411
Pubmed	A direct physical interaction between Nanog and Sox2 regulates embryonic stem cell self-renewal.	RGPD2 RANBP2 RGPD8 SIN3A SALL1 BRCA1 TET1 QSER1	5.80e-08	146	124	8	23892456
Pubmed	Novel retinal and cone photoreceptor transcripts revealed by human macular expression profiling.	NPIPA1 NPIPA5 NPIPA3	1.76e-07	4	124	3	18055785
Pubmed	Identification of a novel Ran binding protein 2 related gene (RANBP2L1) and detection of a gene cluster on human chromosome 2q11-q12.	RANBP2 RGPD8 RGPD5	1.76e-07	4	124	3	9480752
Pubmed	Interaction of Sox2 with RNA binding proteins in mouse embryonic stem cells.	RGPD2 RANBP2 RGPD8 SIN3A KLF4 SALL1 KAT6B	5.86e-07	135	124	7	31077711
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	SECISBP2L GGNBP2 RHOBTB3 SLCO4A1 BTAF1 SIN3A PIAS1 ANKRD27 CEMIP GRPEL1 DST QSER1 SEC23B	6.20e-07	650	124	13	38777146
Pubmed	Interconversion of red opsin isoforms by the cyclophilin-related chaperone protein Ran-binding protein 2.	RGPD2 RANBP2 RGPD8	1.53e-06	7	124	3	9037092
Pubmed	Complex genomic rearrangements lead to novel primate gene function.	RGPD2 RGPD8 RGPD5	1.53e-06	7	124	3	15710750
Pubmed	Genomic organization, expression, and localization of murine Ran-binding protein 2 (RanBP2) gene.	RGPD2 RANBP2 RGPD8	1.53e-06	7	124	3	11353387
Pubmed	Microglial activation in an amyotrophic lateral sclerosis-like model caused by Ranbp2 loss and nucleocytoplasmic transport impairment in retinal ganglion neurons.	RGPD2 RANBP2 RGPD8	1.53e-06	7	124	3	30944974
Pubmed	Nucleoporin Nup358 drives the differentiation of myeloid-biased multipotent progenitors by modulating HDAC3 nuclear translocation.	RGPD2 RANBP2 RGPD8	1.53e-06	7	124	3	38838144
Pubmed	Retina-specifically expressed novel subtypes of bovine cyclophilin.	RGPD2 RANBP2 RGPD8	1.53e-06	7	124	3	7559465
Pubmed	Mst1, RanBP2 and eIF4G are new markers for in vivo PI3K activation in murine and human prostate.	RGPD2 RANBP2 RGPD8	1.53e-06	7	124	3	17372272
Pubmed	Proteostatic Remodeling of Small Heat Shock Chaperones─Crystallins by Ran-Binding Protein 2─and the Peptidyl-Prolyl cis-trans Isomerase and Chaperone Activities of Its Cyclophilin Domain.	RGPD2 RANBP2 RGPD8	1.53e-06	7	124	3	38657106
Pubmed	Nup358, a nucleoporin, functions as a key determinant of the nuclear pore complex structure remodeling during skeletal myogenesis.	RGPD2 RANBP2 RGPD8	1.53e-06	7	124	3	21205196
Pubmed	Haploinsufficiency of RanBP2 is neuroprotective against light-elicited and age-dependent degeneration of photoreceptor neurons.	RGPD2 RANBP2 RGPD8	1.53e-06	7	124	3	18949001
Pubmed	Selective impairment of a subset of Ran-GTP-binding domains of ran-binding protein 2 (Ranbp2) suffices to recapitulate the degeneration of the retinal pigment epithelium (RPE) triggered by Ranbp2 ablation.	RGPD2 RANBP2 RGPD8	1.53e-06	7	124	3	25187515
Pubmed	Localization of the Ran-GTP binding protein RanBP2 at the cytoplasmic side of the nuclear pore complex.	RGPD2 RANBP2 RGPD8	1.53e-06	7	124	3	8603673
Pubmed	Uncoupling phototoxicity-elicited neural dysmorphology and death by insidious function and selective impairment of Ran-binding protein 2 (Ranbp2).	RGPD2 RANBP2 RGPD8	1.53e-06	7	124	3	26632511
Pubmed	Differential loss of prolyl isomerase or chaperone activity of Ran-binding protein 2 (Ranbp2) unveils distinct physiological roles of its cyclophilin domain in proteostasis.	RGPD2 RANBP2 RGPD8	1.53e-06	7	124	3	24403063
Pubmed	Distinct and atypical intrinsic and extrinsic cell death pathways between photoreceptor cell types upon specific ablation of Ranbp2 in cone photoreceptors.	RGPD2 RANBP2 RGPD8	1.53e-06	7	124	3	23818861
Pubmed	Kinesin-1 and mitochondrial motility control by discrimination of structurally equivalent but distinct subdomains in Ran-GTP-binding domains of Ran-binding protein 2.	RGPD2 RANBP2 RGPD8	1.53e-06	7	124	3	23536549
Pubmed	Identification of RanBP2- and kinesin-mediated transport pathways with restricted neuronal and subcellular localization.	RGPD2 RANBP2 RGPD8	1.53e-06	7	124	3	12191015
Pubmed	Ranbp2 haploinsufficiency mediates distinct cellular and biochemical phenotypes in brain and retinal dopaminergic and glia cells elicited by the Parkinsonian neurotoxin, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).	RGPD2 RANBP2 RGPD8	1.53e-06	7	124	3	22821000
Pubmed	Neuroprotection resulting from insufficiency of RANBP2 is associated with the modulation of protein and lipid homeostasis of functionally diverse but linked pathways in response to oxidative stress.	RGPD2 RANBP2 RGPD8	1.53e-06	7	124	3	20682751
Pubmed	The ability of inner-cell-mass cells to self-renew as embryonic stem cells is acquired following epiblast specification.	KLF4 AXIN2 JAK1 JAK3 BMP5 NOTCH2	1.65e-06	100	124	6	24859004
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	RANBP2 LIN54 CUL9 BTAF1 SIN3A MDM4 UBE4A NOP14 SALL1 NFIX PKP1 QSER1 OBI1 NOTCH2	2.43e-06	857	124	14	25609649
Pubmed	The nucleoporin RanBP2 tethers the cAMP effector Epac1 and inhibits its catalytic activity.	RGPD2 RANBP2 RGPD8	2.45e-06	8	124	3	21670213
Pubmed	Critical role of RanBP2-mediated SUMOylation of Small Heterodimer Partner in maintaining bile acid homeostasis.	RGPD2 RANBP2 RGPD8	2.45e-06	8	124	3	27412403
Pubmed	Mice lacking Ran binding protein 1 are viable and show male infertility.	RGPD2 RANBP2 RGPD8	2.45e-06	8	124	3	21310149
Pubmed	The distribution of phosphorylated SR proteins and alternative splicing are regulated by RANBP2.	RGPD2 RANBP2 RGPD8	2.45e-06	8	124	3	22262462
Pubmed	Zap70 and downstream RanBP2 are required for the exact timing of the meiotic cell cycle in oocytes.	RGPD2 RANBP2 RGPD8	2.45e-06	8	124	3	28745977
Pubmed	Resolution of sister centromeres requires RanBP2-mediated SUMOylation of topoisomerase IIalpha.	RGPD2 RANBP2 RGPD8	3.66e-06	9	124	3	18394993
Pubmed	Loss of Ranbp2 in motoneurons causes disruption of nucleocytoplasmic and chemokine signaling, proteostasis of hnRNPH3 and Mmp28, and development of amyotrophic lateral sclerosis-like syndromes.	RGPD2 RANBP2 RGPD8	3.66e-06	9	124	3	28100513
Pubmed	Association of the kinesin-binding domain of RanBP2 to KIF5B and KIF5C determines mitochondria localization and function.	RGPD2 RANBP2 RGPD8	3.66e-06	9	124	3	17887960
Pubmed	The docking of kinesins, KIF5B and KIF5C, to Ran-binding protein 2 (RanBP2) is mediated via a novel RanBP2 domain.	RGPD2 RANBP2 RGPD8	3.66e-06	9	124	3	11553612
Pubmed	The zinc finger cluster domain of RanBP2 is a specific docking site for the nuclear export factor, exportin-1.	RGPD2 RANBP2 RGPD8	3.66e-06	9	124	3	10601307
Pubmed	The cyclophilin-like domain mediates the association of Ran-binding protein 2 with subunits of the 19 S regulatory complex of the proteasome.	RGPD2 RANBP2 RGPD8	3.66e-06	9	124	3	9733766
Pubmed	Impairments in age-dependent ubiquitin proteostasis and structural integrity of selective neurons by uncoupling Ran GTPase from the Ran-binding domain 3 of Ranbp2 and identification of novel mitochondrial isoforms of ubiquitin-conjugating enzyme E2I (ubc9) and Ranbp2.	RGPD2 RANBP2 RGPD8	3.66e-06	9	124	3	28877029
Pubmed	Hierarchy of protein tyrosine kinases in interleukin-2 (IL-2) signaling: activation of syk depends on Jak3; however, neither Syk nor Lck is required for IL-2-mediated STAT activation.	LCK JAK1 JAK3	5.21e-06	10	124	3	10825200
Pubmed	The RanBP2/RanGAP1*SUMO1/Ubc9 SUMO E3 ligase is a disassembly machine for Crm1-dependent nuclear export complexes.	RGPD2 RANBP2 RGPD8	5.21e-06	10	124	3	27160050
Pubmed	Parkin ubiquitinates and promotes the degradation of RanBP2.	RGPD2 RANBP2 RGPD8	5.21e-06	10	124	3	16332688
Pubmed	Cyclophilin-related protein RanBP2 acts as chaperone for red/green opsin.	RGPD2 RANBP2 RGPD8	5.21e-06	10	124	3	8857542
Pubmed	Ran-dependent docking of importin-beta to RanBP2/Nup358 filaments is essential for protein import and cell viability.	RGPD2 RANBP2 RGPD8	5.21e-06	10	124	3	21859863
Pubmed	RanBP2 modulates Cox11 and hexokinase I activities and haploinsufficiency of RanBP2 causes deficits in glucose metabolism.	RGPD2 RANBP2 RGPD8	7.15e-06	11	124	3	17069463
Pubmed	Role of LGR5-positive mesenchymal cells in craniofacial development.	SFRP2 AXIN2 RSPO3	7.15e-06	11	124	3	36133922
Pubmed	An Rtn4/Nogo-A-interacting micropeptide modulates synaptic plasticity with age.	RGPD2 RANBP2 RGPD8	7.15e-06	11	124	3	35771867
Pubmed	T-cell receptor (TCR) signaling promotes the assembly of RanBP2/RanGAP1-SUMO1/Ubc9 nuclear pore subcomplex via PKC-θ-mediated phosphorylation of RanGAP1.	RGPD2 RANBP2 RGPD8	7.15e-06	11	124	3	34110283
Pubmed	O-fucosylation of thrombospondin type 1 repeats restricts epithelial to mesenchymal transition (EMT) and maintains epiblast pluripotency during mouse gastrulation.	ADAMTSL1 THSD7A ADAMTS10 CCN5 C6	7.51e-06	75	124	5	20637190
Pubmed	Functional proteomics mapping of a human signaling pathway.	PAPPA2 VWF THSD7A PPP1R3B PIAS1 ANKRD27 DST RNF4 UBA6 PAPPA NOTCH2	9.31e-06	591	124	11	15231748
Pubmed	Ankyrin-G induces nucleoporin Nup358 to associate with the axon initial segment of neurons.	RGPD2 RANBP2 RGPD8	1.23e-05	13	124	3	31427429
Pubmed	Noncyclic Notch activity in the presomitic mesoderm demonstrates uncoupling of somite compartmentalization and boundary formation.	MYF5 AXIN2 NOTCH2	1.23e-05	13	124	3	18708576
Pubmed	BRCA1 is a new MITF target gene.	BRCA1 MITF	1.26e-05	2	124	2	21501420
Pubmed	Bone morphogenetic proteins 2 and 5 are down-regulated in adrenocortical carcinoma and modulate adrenal cell proliferation and steroidogenesis.	BMP2 BMP5	1.26e-05	2	124	2	19584291
Pubmed	Somatic mutations of JAK1 and JAK3 in acute leukemias and solid cancers.	JAK1 JAK3	1.26e-05	2	124	2	18559588
Pubmed	JAK1 rs310241 and JAK3 rs3008 Genotypes May Increase Susceptibility to Psoriasis: A Case Control Study.	JAK1 JAK3	1.26e-05	2	124	2	32877908
Pubmed	Pregnancy-associated plasma protein-A2 (PAPP-A2): tissue expression and biological consequences of gene knockout in mice.	PAPPA2 PAPPA	1.26e-05	2	124	2	21586553
Pubmed	Absence of gain-of-function JAK1 and JAK3 mutations in adult T cell leukemia/lymphoma.	JAK1 JAK3	1.26e-05	2	124	2	20697856
Pubmed	Recurrent JAK1 and JAK3 somatic mutations in T-cell prolymphocytic leukemia.	JAK1 JAK3	1.26e-05	2	124	2	24048415
Pubmed	Mechanism of Janus kinase 3-catalyzed phosphorylation of a Janus kinase 1 activation loop peptide.	JAK1 JAK3	1.26e-05	2	124	2	12559972
Pubmed	Congenital dyserythropoietic anemia in China: a case report from two families and a review.	CDAN1 SEC23B	1.26e-05	2	124	2	24196372
Pubmed	Kr-POK (ZBTB7c) regulates cancer cell proliferation through glutamine metabolism.	ZBTB7C PIAS1	1.26e-05	2	124	2	28571744
Pubmed	BMP2-dependent gene regulatory network analysis reveals Klf4 as a novel transcription factor of osteoblast differentiation.	KLF4 BMP2	1.26e-05	2	124	2	33608506
Pubmed	Loss of ZC4H2 and RNF220 Inhibits Neural Stem Cell Proliferation and Promotes Neuronal Differentiation.	ZC4H2 RNF220	1.26e-05	2	124	2	32630355
Pubmed	Zfp296 is a novel Klf4-interacting protein and functions as a negative regulator.	KLF4 ZNF296	1.26e-05	2	124	2	24161396
Pubmed	Mutational analysis of the proteolytic domain of pregnancy-associated plasma protein-A (PAPP-A): classification as a metzincin.	PAPPA2 PAPPA	1.26e-05	2	124	2	11513734
Pubmed	Cooperating JAK1 and JAK3 mutants increase resistance to JAK inhibitors.	JAK1 JAK3	1.26e-05	2	124	2	25352124
Pubmed	Sin3A recruits Tet1 to the PAH1 domain via a highly conserved Sin3-Interaction Domain.	SIN3A TET1	1.26e-05	2	124	2	30279502
Pubmed	Positive selection of a gene family during the emergence of humans and African apes.	NPIPA1 NPIPA8	1.26e-05	2	124	2	11586358
Pubmed	Plakophilin 1-deficient cells upregulate SPOCK1: implications for prostate cancer progression.	SPOCK1 PKP1	1.26e-05	2	124	2	26138584
Pubmed	Janus kinase-1 and 3 in ankylosing spondylitis.	JAK1 JAK3	1.26e-05	2	124	2	29530480
Pubmed	Pregnancy associated plasma protein-A as a prognostic biomarker of all-cause mortality and cardiovascular events in patients presenting with chest pain: a systematic review.	PAPPA2 PAPPA	1.26e-05	2	124	2	29144175
Pubmed	Polymorphisms in complement genes and risk of preeclampsia in Taiyuan, China.	MASP1 C6	1.26e-05	2	124	2	27405496
Pubmed	Janus kinase inhibition prevents cancer- and myocardial infarction-mediated diaphragm muscle weakness in mice.	JAK1 JAK3	1.26e-05	2	124	2	26864813
Pubmed	Janus kinase 1/3 signaling pathways are key initiators of TH2 differentiation and lung allergic responses.	JAK1 JAK3	1.26e-05	2	124	2	24365136
Pubmed	JAK3 mutants transform hematopoietic cells through JAK1 activation, causing T-cell acute lymphoblastic leukemia in a mouse model.	JAK1 JAK3	1.26e-05	2	124	2	25193870
Pubmed	Targeting WNT1-inducible signaling pathway protein 2 alters human breast cancer cell susceptibility to specific lysis through regulation of KLF-4 and miR-7 expression.	KLF4 CCN5	1.26e-05	2	124	2	24931170
Pubmed	Sin3a-Tet1 interaction activates gene transcription and is required for embryonic stem cell pluripotency.	SIN3A TET1	1.26e-05	2	124	2	29733394
Pubmed	Drug-gene interactions and the search for missing heritability: a cross-sectional pharmacogenomics study of the QT interval.	ADAMTSL1 LRFN5 ROS1	1.56e-05	14	124	3	23459443
Pubmed	Systematic identification of factors for provirus silencing in embryonic stem cells.	RGPD2 RANBP2 RGPD8 SIN3A BRCA1 SEC23B	1.91e-05	153	124	6	26365490
Pubmed	Trim43a, Trim43b, and Trim43c: Novel mouse genes expressed specifically in mouse preimplantation embryos.	TRIM64 TRIM64C TRIM64B	1.95e-05	15	124	3	19703589
Pubmed	Lrp4/Wise regulates palatal rugae development through Turing-type reaction-diffusion mechanisms.	AXIN2 BMP2 BMP5	1.95e-05	15	124	3	30235284
Pubmed	Limited expression of nuclear pore membrane glycoprotein 210 in cell lines and tissues suggests cell-type specific nuclear pores in metazoans.	RGPD2 RANBP2 RGPD8	1.95e-05	15	124	3	14697343
Pubmed	Activity-based E3 ligase profiling uncovers an E3 ligase with esterification activity.	CUL9 PIAS1 RNF220 RNF167 UBA6	2.38e-05	95	124	5	29643511
Pubmed	The T cell protein tyrosine phosphatase is a negative regulator of janus family kinases 1 and 3.	JAK1 JAK3	3.77e-05	3	124	2	11909529
Pubmed	Frequency and prognostic implications of JAK 1-3 aberrations in Down syndrome acute lymphoblastic and myeloid leukemia.	JAK1 JAK3	3.77e-05	3	124	2	21537335
Pubmed	Particular Role of JAK/STAT3 Signaling in Functional Control of Mesenchymal Progenitor Cells.	JAK1 JAK3	3.77e-05	3	124	2	29308566
Pubmed	Constitutive activation of the Janus kinase-STAT pathway in T lymphoma overexpressing the Lck protein tyrosine kinase.	LCK JAK1	3.77e-05	3	124	2	9548458
Pubmed	Fes mediates the IL-4 activation of insulin receptor substrate-2 and cellular proliferation.	JAK1 JAK3	3.77e-05	3	124	2	11160325
Pubmed	Structural organization and chromosomal mapping of JAK3 locus.	JAK1 JAK3	3.77e-05	3	124	2	8934548
Pubmed	Sequential stabilization of RNF220 by RLIM and ZC4H2 during cerebellum development and Shh-group medulloblastoma progression.	ZC4H2 RNF220	3.77e-05	3	124	2	35040952
Pubmed	Identification of CDAN1, C15ORF41 and SEC23B mutations in Chinese patients affected by congenital dyserythropoietic anemia.	CDAN1 SEC23B	3.77e-05	3	124	2	29031773
Pubmed	Implication of JAK1, JAK2, and JAK3 in the Realization of Proliferation and Differentiation Potential of Mesenchymal Progenitor Cells In Vitro.	JAK1 JAK3	3.77e-05	3	124	2	27383175
Pubmed	Positive regulation of interleukin-4-mediated proliferation by the SH2-containing inositol-5'-phosphatase.	JAK1 JAK3	3.77e-05	3	124	2	10875931
Pubmed	Age-associated inflammation inhibits epidermal stem cell function.	JAK1 JAK3	3.77e-05	3	124	2	22972935
Pubmed	TET1 inhibits EMT of ovarian cancer cells through activating Wnt/β-catenin signaling inhibitors DKK1 and SFRP2.	SFRP2 TET1	3.77e-05	3	124	2	28851501
Pubmed	Cell biology of IL-7, a key lymphotrophin.	JAK1 JAK3	3.77e-05	3	124	2	15996891
Pubmed	RNF220 mediates K63-linked polyubiquitination of STAT1 and promotes host defense.	JAK1 RNF220	3.77e-05	3	124	2	32814877
Pubmed	Modulation of innate and adaptive immune responses by tofacitinib (CP-690,550).	JAK1 JAK3	3.77e-05	3	124	2	21383241
Pubmed	LCK facilitates DNA damage repair by stabilizing RAD51 and BRCA1 in the nucleus of chemoresistant ovarian cancer.	LCK BRCA1	3.77e-05	3	124	2	37370140
Pubmed	Bone morphogenetic proteins and secreted frizzled related protein 2 maintain the quiescence of adult mammalian retinal stem cells.	SFRP2 BMP2	3.77e-05	3	124	2	23843349
Interaction	RGPD4 interactions	RGPD2 RANBP2 RGPD8 RGPD5	7.28e-06	22	117	4	int:RGPD4
Cytoband	16p13.11	NPIPA1 NPIPA5 NPIPA3	3.20e-05	23	123	3	16p13.11
GeneFamily	Pappalysins\|Sushi domain containing	PAPPA2 PAPPA	1.84e-05	2	78	2	897
GeneFamily	Ring finger proteins	TRIM64 TRIM64C TRIM64B RNF220 RNF167 RNF4 BRCA1 OBI1	2.42e-05	275	78	8	58
GeneFamily	Hyalectan proteoglycans\|V-set domain containing\|Sushi domain containing\|C-type lectin domain containing	PAPPA2 MASP1 PAPPA C6	1.06e-04	57	78	4	1179
GeneFamily	VPS9 domain containing	ALS2 ANKRD27	8.09e-04	10	78	2	928
GeneFamily	Bone morphogenetic proteins\|Astacins	BMP2 BMP5	9.85e-04	11	78	2	455
GeneFamily	Tetratricopeptide repeat domain containing\|Bardet-Biedl syndrome associated\|BBSome	RGPD2 RANBP2 RGPD8 RGPD5	1.54e-03	115	78	4	769
GeneFamily	Endogenous ligands	VWF RSPO3 BMP2 BMP5 RAC2	3.60e-03	237	78	5	542
GeneFamily	Phosphodiesterases	PDE8A PDE5A	4.77e-03	24	78	2	681
Coexpression	NABA_MATRISOME	PAPPA2 MASP1 ADAMTSL1 SFRP2 VWF SPOCK1 ADAMTS10 CCN5 RSPO3 BMP2 BMP5 CST3 PAPPA FGF11 GPC5 TNR PCOLCE	4.43e-06	1008	122	17	MM17056
Coexpression	NABA_MATRISOME	PAPPA2 MASP1 ADAMTSL1 SFRP2 VWF SPOCK1 ADAMTS10 CCN5 RSPO3 BMP2 BMP5 CST3 PAPPA FGF11 GPC5 TNR PCOLCE	5.60e-06	1026	122	17	M5889
Coexpression	JINESH_BLEBBISHIELD_VS_LIVE_CONTROL_UP	USP49 AEN TCAF1 VWF GLS2 CUL9 KLF4 CDAN1 ZNF296 ANKRD11	1.19e-05	380	122	10	M38974
Coexpression	AIZARANI_LIVER_C21_STELLATE_CELLS_1	MASP1 KLF4 BMP2 NFIX MITF FILIP1L PCOLCE	3.57e-05	194	122	7	M39122
Coexpression	MEISSNER_BRAIN_HCP_WITH_H3K4ME3_AND_H3K27ME3	SFRP2 ZBTB7C PDE8A PPP1R3B KLF4 CEMIP RSPO3 BMP2 RNF220 SALL1 ZNF296 NFIX PAPPA PDE5A FGF11 GPC5	3.94e-05	1074	122	16	M1941
CoexpressionAtlas	FacebaseRNAseq_e8.5_Paraxial Mesoderm_top-relative-expression-ranked_500	ADAMTSL1 SFRP2 VWF PPP1R3B SLCO4A1 KLF4 SALL1 NFIX FGF11 GPC5 RAC2 FILIP1L CCSER1	2.78e-06	489	116	13	Facebase_RNAseq_e8.5_Paraxial Mesoderm_500
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ Genital tubercle F_emap-6706_top-relative-expression-ranked_1000	ADAMTSL1 THSD7A SPOCK1 PPP1R3B SLCO4A1 KLF4 PIAS1 AXIN2 CEMIP RSPO3 BMP2 BMP5 DST SALL1 SERTAD4 PDE5A KAT6B	3.68e-06	850	116	17	gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle F_1000
CoexpressionAtlas	DevelopingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_emap-3087_top-relative-expression-ranked_1000	THSD7A SPOCK1 ZC4H2 KLF4 CEMIP RSPO3 BMP2 BMP5 DST SALL1 LRFN5 SERTAD4 SYT4 PDE5A KAT6B CCSER1	1.11e-05	827	116	16	gudmap_developingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_1000
CoexpressionAtlas	FacebaseRNAseq_e9.5_Maxillary Arch_top-relative-expression-ranked_1000_k-means-cluster#1	ADAMTSL1 VWF PDE8A SLCO4A1 KLF4 NFIX MITF GPC5 RAC2 FILIP1L	3.71e-05	371	116	10	Facebase_RNAseq_e9.5_Maxillary Arch_1000_K1
CoexpressionAtlas	DevelopingKidney_e15.5_Peripheral blastema_emap-27731_top-relative-expression-ranked_200	ADAMTSL1 ZBTB7C PPP1R3B RSPO3 SALL1 SERTAD4 PAPPA	5.02e-05	175	116	7	gudmap_developingKidney_e15.5_Peripheral blastema_200
CoexpressionAtlas	dev gonad_e13.5_M_SertoliCell_Sox9_k-means-cluster#4_top-relative-expression-ranked_1000	SECISBP2L MASP1 REXO5 RHOBTB3 ARHGAP39 CEMIP CDAN1 DST CST3 PAPPA NOTCH2	5.84e-05	474	116	11	gudmap_dev gonad_e13.5_M_SertoliCell_Sox9_k4_1000
CoexpressionAtlas	FacebaseRNAseq_e8.5_Paraxial Mesoderm_top-relative-expression-ranked_500_k-means-cluster#3	ADAMTSL1 VWF SLCO4A1 KLF4 NFIX GPC5 RAC2 FILIP1L	6.83e-05	249	116	8	Facebase_RNAseq_e8.5_Paraxial Mesoderm_500_K3
CoexpressionAtlas	dev gonad_e12.5_M_SertoliCell_Sox9_k-means-cluster#3_top-relative-expression-ranked_1000	MASP1 RHOBTB3 PDE5A NOTCH2 PCOLCE	7.28e-05	79	116	5	gudmap_dev gonad_e12.5_M_SertoliCell_Sox9_k3_1000
CoexpressionAtlas	dev gonad_e13.5_M_SertoliCell_Sox9_top-relative-expression-ranked_1000	SECISBP2L MASP1 REXO5 PDE8A RHOBTB3 ARHGAP39 CEMIP CDAN1 DST BRCA1 CST3 PAPPA PDE5A NOTCH2 PCOLCE	9.00e-05	880	116	15	gudmap_dev gonad_e13.5_M_SertoliCell_Sox9_1000
CoexpressionAtlas	dev lower uro neuro_e15.5_PelvicGanglion_Sox10_k-means-cluster#4_top-relative-expression-ranked_1000	MASP1 ADAMTSL1 SFRP2 RSPO3 ATRNL1 CST3 PAPPA PDE5A	9.47e-05	261	116	8	gudmap_dev lower uro neuro_e15.5_PelvicGanglion_Sox10_k4_1000
CoexpressionAtlas	FacebaseRNAseq_e10.5_Olfactory Pit_top-relative-expression-ranked_1000_k-means-cluster#5	ADAMTSL1 VWF SLCO4A1 KLF4 NFIX GPC5 RAC2 FILIP1L	1.39e-04	276	116	8	Facebase_RNAseq_e10.5_Olfactory Pit_1000_K5
CoexpressionAtlas	DevelopingKidney_e15.5_Peripheral blastema_emap-27731_top-relative-expression-ranked_1000	ADAMTSL1 THSD7A ZBTB7C PPP1R3B RHOBTB3 KLF4 RSPO3 SALL1 PER3 BRCA1 TET1 SERTAD4 PAPPA FILIP1L	1.52e-04	819	116	14	gudmap_developingKidney_e15.5_Peripheral blastema_1000
CoexpressionAtlas	facebase_RNAseq_e14.5_palate_poster_oral_Tgfbr2_WT_2500_K4	MASP1 ADAMTSL1 VWF ZBTB7C PDE8A PPP1R3B ADAMTS10 RSPO3 BMP5 ATRNL1 SERTAD4 PKP1 IPO13 FGF11 GPC5 KAT6B FILIP1L	1.64e-04	1148	116	17	facebase_RNAseq_e14.5_palate_poster_oral_Tgfbr2_WT_2500_K4
CoexpressionAtlas	FacebaseRNAseq_e8.5_Paraxial Mesoderm_top-relative-expression-ranked_2500_k-means-cluster#4	PDE8A SLCO4A1 KLF4 ADAMTS10 HAUS4 NFIX ATRNL1 FECH SERTAD4 GPC5 RAC2 FILIP1L PCOLCE	1.81e-04	731	116	13	Facebase_RNAseq_e8.5_Paraxial Mesoderm_2500_K4
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_k-means-cluster#2_top-relative-expression-ranked_1000	THSD7A SPOCK1 KLF4 CEMIP RSPO3 SERTAD4	1.83e-04	151	116	6	gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_1000_k2
CoexpressionAtlas	FacebaseRNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_top-relative-expression-ranked_2500_k-means-cluster#5	VWF PDE8A SLCO4A1 KLF4 HAUS4 NFIX ATRNL1 FECH SERTAD4 GPC5 RAC2 FILIP1L PCOLCE	1.89e-04	734	116	13	Facebase_RNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_2500_K5
CoexpressionAtlas	dev lower uro neuro_e15.5_PelvicGanglion_Sox10_top-relative-expression-ranked_1000	MASP1 ADAMTSL1 SFRP2 HMGCR RSPO3 NFIX ATRNL1 CST3 SYT4 PAPPA PDE5A DISP2 TNR	1.89e-04	734	116	13	gudmap_dev lower uro neuro_e15.5_PelvicGanglion_Sox10_1000
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ Genital tubercle_emap-6706_top-relative-expression-ranked_200	SPOCK1 RSPO3 BMP5 DST SALL1 PKP1	2.26e-04	157	116	6	gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle_200
CoexpressionAtlas	FacebaseRNAseq_e8.5_Non-Floor Plate Neural Epithelium_top-relative-expression-ranked_1000_k-means-cluster#4	ADAMTSL1 VWF SLCO4A1 KLF4 NFIX GPC5 RAC2 FILIP1L	2.35e-04	298	116	8	Facebase_RNAseq_e8.5_Non-Floor Plate Neural Epithelium_1000_K4
CoexpressionAtlas	FacebaseRNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_top-relative-expression-ranked_1000	PAPPA2 MASP1 ADAMTSL1 SFRP2 VWF PDE8A PPP1R3B SLCO4A1 KLF4 NFIX FGF11 GPC5 RAC2 FILIP1L CCSER1	2.52e-04	967	116	15	Facebase_RNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_1000
CoexpressionAtlas	FacebaseRNAseq_e8.5_Paraxial Mesoderm_top-relative-expression-ranked_1000	PAPPA2 ADAMTSL1 SFRP2 VWF PDE8A PPP1R3B SLCO4A1 KLF4 SALL1 NFIX FGF11 GPC5 RAC2 FILIP1L CCSER1	2.52e-04	967	116	15	Facebase_RNAseq_e8.5_Paraxial Mesoderm_1000
CoexpressionAtlas	FacebaseRNAseq_e9.5_Facial Mesenchyne_top-relative-expression-ranked_1000	PAPPA2 ADAMTSL1 SFRP2 VWF PDE8A PPP1R3B SLCO4A1 KLF4 SALL1 NFIX FGF11 GPC5 RAC2 FILIP1L CCSER1	2.55e-04	968	116	15	Facebase_RNAseq_e9.5_Facial Mesenchyne_1000
CoexpressionAtlas	FacebaseRNAseq_e9.5_Facial Mesenchyne_top-relative-expression-ranked_1000_k-means-cluster#3	PAPPA2 ADAMTSL1 PDE8A SLCO4A1 KLF4 NFIX GPC5 RAC2 FILIP1L	2.62e-04	384	116	9	Facebase_RNAseq_e9.5_Facial Mesenchyne_1000_K3
CoexpressionAtlas	DevelopingKidney_e15.5_Pelvic Mesenchyme_emap-8241_k-means-cluster#2_top-relative-expression-ranked_1000	ADAMTSL1 SFRP2 BMP5 LRFN5 ATRNL1 SERTAD4 SYT4 CCSER1	2.74e-04	305	116	8	gudmap_developingKidney_e15.5_Pelvic Mesenchyme_1000_k2
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ Genital tubercle_emap-6706_top-relative-expression-ranked_500	SPOCK1 KLF4 AXIN2 RSPO3 BMP5 DST SALL1 PKP1 KAT6B	2.93e-04	390	116	9	gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle_500
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ Genital tubercle_emap-6706_top-relative-expression-ranked_1000	ADAMTSL1 THSD7A SPOCK1 KLF4 AXIN2 RSPO3 BMP5 DST SALL1 NFIX SERTAD4 PKP1 KAT6B	2.96e-04	769	116	13	gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle_1000
CoexpressionAtlas	FacebaseRNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_top-relative-expression-ranked_500	PAPPA2 MASP1 ADAMTSL1 SFRP2 PPP1R3B NFIX FGF11 GPC5 FILIP1L CCSER1	3.00e-04	479	116	10	Facebase_RNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_500
CoexpressionAtlas	DevelopingKidney_e15.5_Peripheral blastema_emap-27731_k-means-cluster#2_top-relative-expression-ranked_1000	ADAMTSL1 THSD7A ZBTB7C PPP1R3B SERTAD4 PAPPA FILIP1L	3.04e-04	234	116	7	gudmap_developingKidney_e15.5_Peripheral blastema_1000_k2
CoexpressionAtlas	DevelopingKidney_e14.5 whole kidney - Wnt4 KO_emap-6674_top-relative-expression-ranked_1000	ADAMTSL1 ZC4H2 KLF4 RSPO3 BMP5 NFIX SERTAD4 ANKRD11 UBA6 PAPPA PDE5A FGF11 KAT6B	3.87e-04	791	116	13	gudmap_developingKidney_e14.5 whole kidney - Wnt4 KO_1000
CoexpressionAtlas	DevelopingKidney_e15.5_Peripheral blastema_emap-27731_k-means-cluster#2_top-relative-expression-ranked_200	ADAMTSL1 ZBTB7C PPP1R3B SERTAD4 PAPPA	4.42e-04	116	116	5	gudmap_developingKidney_e15.5_Peripheral blastema_200_k2
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_top-relative-expression-ranked_1000	SFRP2 THSD7A SPOCK1 PPP1R3B RHOBTB3 CEMIP RSPO3 BMP5 DST SALL1 NFIX PKP1 PDE5A	4.63e-04	806	116	13	gudmap_developingLowerUrinaryTract_e14.5_ urethra_1000
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_top-relative-expression-ranked_1000	PAPPA2 ADAMTSL1 SFRP2 THSD7A SPOCK1 RHOBTB3 JAK1 BMP5 NFIX PDE5A DISP2 KAT6B CCSER1	5.31e-04	818	116	13	gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_1000
CoexpressionAtlas	DevelopingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_emap-3087_top-relative-expression-ranked_500	SPOCK1 KLF4 CEMIP RSPO3 BMP2 SALL1 SERTAD4 SYT4 CCSER1	5.38e-04	424	116	9	gudmap_developingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_500
CoexpressionAtlas	FacebaseRNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_1000_k-means-cluster#1	PDE8A SLCO4A1 KLF4 NFIX GPC5 RAC2 FILIP1L	6.39e-04	265	116	7	Facebase_RNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_1000_K1
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_top-relative-expression-ranked_1000	ADAMTSL1 THSD7A SPOCK1 KLF4 CEMIP RSPO3 BMP2 BMP5 DST SALL1 SERTAD4 PDE5A KAT6B	6.51e-04	836	116	13	gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_1000
CoexpressionAtlas	dev lower uro neuro_e15.5_PelvicGanglion_Sox10_k-means-cluster#2_top-relative-expression-ranked_500	MASP1 ADAMTSL1 SFRP2 PAPPA PDE5A	6.68e-04	127	116	5	gudmap_dev lower uro neuro_e15.5_PelvicGanglion_Sox10_k2_500
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ Genital tubercle F_emap-6706_k-means-cluster#1_top-relative-expression-ranked_1000	THSD7A SPOCK1 KLF4 CEMIP RSPO3 SERTAD4	6.76e-04	193	116	6	gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle F_1000_k1
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ Genital tubercle F_emap-6706_k-means-cluster#2_top-relative-expression-ranked_1000	PPP1R3B SLCO4A1 BMP2 DST	6.88e-04	73	116	4	gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle F_1000_k2
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_k-means-cluster#2_top-relative-expression-ranked_1000	ADAMTSL1 BMP5 NFIX PDE5A	6.88e-04	73	116	4	gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_1000_k2
CoexpressionAtlas	FacebaseRNAseq_e9.5_Maxillary Arch_top-relative-expression-ranked_1000	ADAMTSL1 SFRP2 VWF PDE8A PPP1R3B SLCO4A1 KLF4 NFIX MITF FGF11 GPC5 RAC2 FILIP1L CCSER1	8.08e-04	967	116	14	Facebase_RNAseq_e9.5_Maxillary Arch_1000
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ Genital tubercle_emap-6706_k-means-cluster#5_top-relative-expression-ranked_100	SPOCK1 SALL1	8.11e-04	8	116	2	gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle_100_k5
CoexpressionAtlas	FacebaseRNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_1000	ADAMTSL1 SFRP2 VWF THSD7A PDE8A PPP1R3B SLCO4A1 KLF4 NFIX FGF11 GPC5 RAC2 FILIP1L CCSER1	8.49e-04	972	116	14	Facebase_RNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_1000
CoexpressionAtlas	FacebaseRNAseq_e9.5_Olfactory Placode_top-relative-expression-ranked_1000	ADAMTSL1 SFRP2 VWF PPP1R3B SLCO4A1 LCK BMP2 BMP5 SALL1 NFIX FGF11 GPC5 FILIP1L CCSER1	8.58e-04	973	116	14	Facebase_RNAseq_e9.5_Olfactory Placode_1000
CoexpressionAtlas	facebase_RNAseq_e14.5_palate_poster_proximal_ERK2_WT_2500_K2	ADAMTSL1 VWF ZBTB7C PDE8A ZBTB48 SIN3A AXIN2 ADAMTS10 RSPO3 TET1 IPO13 PAPPA GPC5 KAT6B NAGPA FILIP1L	8.78e-04	1208	116	16	facebase_RNAseq_e14.5_palate_poster_proximal_ERK2_WT_2500_K2
ToppCell	Lung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Fibroblasts-1\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	SFRP2 RHOBTB3 CCN5 RSPO3 BMP5 DST NFIX FILIP1L PCOLCE	4.81e-09	200	123	9	c3d4ce70ab51d74c9fe2f5864e52a4a9d7570e10
ToppCell	Lung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Fibroblasts-1-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SFRP2 RHOBTB3 CCN5 RSPO3 BMP5 DST NFIX FILIP1L PCOLCE	4.81e-09	200	123	9	137f8f9d255c66336d4f8b44b2e3f3de721f2bf0
ToppCell	Parenchyma_COVID-19-Stromal-TX-Fibroblasts-1\|Parenchyma_COVID-19 / Sample group, Lineage and Cell type	SFRP2 RHOBTB3 CCN5 RSPO3 BMP5 DST NFIX FILIP1L PCOLCE	4.81e-09	200	123	9	25d3865aa2ced11a5ed40013e83b47d942fdf582
ToppCell	COPD-Stromal-Fibroblast\|Stromal / Disease state, Lineage and Cell class	ADAMTSL1 SFRP2 SPOCK1 KLF4 CCN5 RSPO3 CST3 PCOLCE	7.54e-08	196	123	8	4930eeb303d174c28fd91021723e26fdf1af9170
ToppCell	Adult-Mesenchymal-matrix_fibroblast_2_cell-D231\|Adult / Lineage, Cell type, age group and donor	MASP1 ADAMTSL1 SFRP2 ADAMTS10 CCN5 RSPO3 LRFN5	8.43e-07	185	123	7	fb6bd7e849ecf4ed9cd9c4e2a946a2d12d62f804
ToppCell	COVID-19-Fibroblasts-Adventitial_FB\|COVID-19 / group, cell type (main and fine annotations)	ADAMTSL1 SFRP2 SPOCK1 CEMIP RSPO3 LRFN5 PAPPA	8.43e-07	185	123	7	a5aebf2b9b05b550d021272731d68af9a6b1229d
ToppCell	10x3'2.3-week_14-16-Mesenchymal_fibro-stroma-endosteal_fibroblast\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	SFRP2 ZBTB7C RSPO3 LRFN5 PKP1 GPC5 FILIP1L	9.39e-07	188	123	7	0e2d1b21f0a7ee306e7dae16fc8c19d16a467883
ToppCell	ASK454-Mesenchymal\|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq	SFRP2 CEMIP CCN5 BMP5 DST FILIP1L PCOLCE	1.04e-06	191	123	7	e30ae7a12439f8a79820b13f03e822c1223fd0cb
ToppCell	ASK454-Mesenchymal-Fibroblast\|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq	SFRP2 CEMIP CCN5 BMP5 DST FILIP1L PCOLCE	1.04e-06	191	123	7	1726add3f392a061536b7aff72ba84303f4a0b1f
ToppCell	IPF-Stromal-Fibroblast\|Stromal / Disease state, Lineage and Cell class	ADAMTSL1 SFRP2 SPOCK1 KLF4 CCN5 RSPO3 CST3	1.16e-06	194	123	7	da3e1d39575969a069ef43e552afe94b2f441d0b
ToppCell	LV-14._Fibroblast_III\|LV / Chamber and Cluster_Paper	RANBP2 SFRP2 SPOCK1 RHOBTB3 LRFN5 NFIX PAPPA	1.16e-06	194	123	7	927c26aea0147f7a4b8fb3f192de4de263f1b978
ToppCell	droplet-Fat-SCAT-30m-Mesenchymal-mesenchymal_stem_cell_of_adipose\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYF5 ADAMTSL1 SFRP2 KLF4 CCN5 NFIX PCOLCE	1.16e-06	194	123	7	0e315c63407fa00643722a7d6138b1502f79b10d
ToppCell	droplet-Fat-SCAT-30m-Mesenchymal\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYF5 ADAMTSL1 SFRP2 KLF4 CCN5 NFIX PCOLCE	1.16e-06	194	123	7	c2990d6eda3954dc01913bf3910df79f06e0010a
ToppCell	3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PAPPA2 MASP1 CCN5 PAPPA PDE5A FILIP1L PCOLCE	1.28e-06	197	123	7	16758f181ef07c60aee63072e1da9572c5c85414
ToppCell	11.5-Airway-Mesenchymal-Mesenchyme_SERPINF1-high\|Airway / Age, Tissue, Lineage and Cell class	SFRP2 KLF4 RSPO3 NFIX SERTAD4 PAPPA PCOLCE	1.28e-06	197	123	7	9a053a32ff9c3a85ef9a3382453acd619cc48546
ToppCell	PND14-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PAPPA2 ADAMTS10 BMP5 NFIX CST3 PDE5A FILIP1L	1.33e-06	198	123	7	b2d295e330772bd8e24da356c75564b4297ea9c5
ToppCell	distal-mesenchymal-Adventitial_Fibroblast-2\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	SFRP2 CCN5 RSPO3 LRFN5 ATRNL1 PAPPA PCOLCE	1.33e-06	198	123	7	bfd720e2dae3b6b3dc2bf8b2096c554fd456e756
ToppCell	PND14-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PAPPA2 ADAMTS10 BMP5 NFIX CST3 PDE5A FILIP1L	1.33e-06	198	123	7	3ffaea4b44067d69f954b2bd3119c88a55ab232a
ToppCell	Fibroblasts-CD34+_Fibroblasts\|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	SFRP2 RHOBTB3 CCN5 DST NFIX CST3 PCOLCE	1.37e-06	199	123	7	13ff7409e200a0b46cdb7924d15ef33639693622
ToppCell	tumor_Lung-Fibroblasts-COL14A1+_matrix_FBs\|Fibroblasts / Location, Cell class and cell subclass	SFRP2 KLF4 CCN5 RSPO3 CST3 PAPPA PCOLCE	1.37e-06	199	123	7	0d1f2b0d10c1f8ee10c448659b2a22ea0a6a6f0d
ToppCell	Lung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Fibroblasts-3\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	SFRP2 RHOBTB3 CCN5 BMP5 DST FILIP1L PCOLCE	1.42e-06	200	123	7	e663995fc44c340d878d66b278b7b5c2ff784301
ToppCell	Lung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Fibroblasts-2,_SCARA5-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	PAPPA2 SFRP2 SPOCK1 RSPO3 NFIX PAPPA PCOLCE	1.42e-06	200	123	7	0b2614b8513693dd508c9003699049efd9abac52
ToppCell	Bronchial-NucSeq-Stromal-Fibroblastic-Fibro_adventitial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ADAMTSL1 SFRP2 SPOCK1 RSPO3 LRFN5 PAPPA PCOLCE	1.42e-06	200	123	7	ad3fdcef895400f929f2ae12ff9bd85fd46adb3a
ToppCell	3'-Parenchyma_lung-Mesenchymal\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SFRP2 SPOCK1 CCN5 RSPO3 PDE5A FILIP1L PCOLCE	1.42e-06	200	123	7	ba5ed66b05caa1be0bbf8d54c4e72a782b8d9833
ToppCell	Lung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Fibroblasts-2,_SCARA5\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	PAPPA2 SFRP2 SPOCK1 RSPO3 NFIX PAPPA PCOLCE	1.42e-06	200	123	7	8d2ceb2080c67b20f452eeca605aa27a58033c04
ToppCell	cellseq2-Mesenchymal-Fibroblastic-Fibroblastic_1-AF2\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	SFRP2 SPOCK1 CCN5 BMP5 LRFN5 PAPPA PCOLCE	1.42e-06	200	123	7	44317fbf4d1480a37b50ab2777bf1a3e4fc0c05f
ToppCell	Lung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Fibroblasts-3-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SFRP2 RHOBTB3 CCN5 BMP5 DST FILIP1L PCOLCE	1.42e-06	200	123	7	2cb8a39a12522a9643c6244d5e94cb4559868bb9
ToppCell	medial-mesenchymal-Adventitial_Fibroblast\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	SFRP2 SPOCK1 CCN5 RSPO3 LRFN5 PAPPA PCOLCE	1.42e-06	200	123	7	87a5a0c252c08ba10316c21f6a9d5244c4d98c74
ToppCell	Parenchymal-10x3prime_v2-Stromal-Fibroblastic-Fibro_myofibroblast\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	PAPPA2 MASP1 RHOBTB3 CCN5 DST PAPPA FILIP1L	1.42e-06	200	123	7	251fd2923f108cd2086961d897244b392c32ad54
ToppCell	Parenchyma_COVID-19-Stromal-TX-Fibroblasts-3\|Parenchyma_COVID-19 / Sample group, Lineage and Cell type	SFRP2 RHOBTB3 CCN5 BMP5 DST FILIP1L PCOLCE	1.42e-06	200	123	7	8cc5057b0e5ae9b72ea40d2ffbc52b79bf87ccef
ToppCell	medial-2-mesenchymal-Adventitial_Fibroblast\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	SFRP2 SPOCK1 CCN5 RSPO3 LRFN5 PAPPA PCOLCE	1.42e-06	200	123	7	6ccf44f10d2cee5f48b8f05bd9a1b94057184d56
ToppCell	cellseq2-Mesenchymal-Fibroblastic\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	SFRP2 SPOCK1 CCN5 BMP5 LRFN5 PAPPA PCOLCE	1.42e-06	200	123	7	1c10597edd532bf172ca09870a937d35e2585081
ToppCell	Parenchyma_COVID-19-Stromal-TX-Fibroblasts-2,_SCARA5\|Parenchyma_COVID-19 / Sample group, Lineage and Cell type	PAPPA2 SFRP2 SPOCK1 RSPO3 NFIX PAPPA PCOLCE	1.42e-06	200	123	7	c338a08c1605527ab9aaf62ea151a19e8469dc6d
ToppCell	medial-mesenchymal-Adventitial_Fibroblast-2\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	SFRP2 SPOCK1 CCN5 RSPO3 LRFN5 PAPPA PCOLCE	1.42e-06	200	123	7	5ee1318a74ca28a81bd81c20c611de84c17636b0
ToppCell	cellseq2-Mesenchymal-Fibroblastic-Fibroblastic_1\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	SFRP2 SPOCK1 CCN5 BMP5 LRFN5 PAPPA PCOLCE	1.42e-06	200	123	7	440dda48b09c6a8581b7ca634b0d67f1ecacf65e
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-high_Fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTSL1 CEMIP ADAMTS10 BMP5 LRFN5 ATRNL1	5.35e-06	159	123	6	e812cbde59188924c6277c3feadf1a9592fa62a4
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-high_Fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTSL1 CEMIP ADAMTS10 BMP5 LRFN5 ATRNL1	5.35e-06	159	123	6	2607b562903228274fbd96168ba826782fab0b53
ToppCell	343B-Myeloid-Macrophage-FABP4+_Macrophage\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	RGPD8 LIN54 CDAN1 NFIX ZNF256 ROS1	6.85e-06	166	123	6	f62db9d9b6c9dd8f2afcaea0fc5f8c69f50205b2
ToppCell	E15.5-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_vein\|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	VWF PDE8A KLF4 DST SALL1 FILIP1L	8.12e-06	171	123	6	3112d15f2a28cf4a71992db4971d960716dc1264
ToppCell	3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MASP1 CCN5 DST PAPPA PDE5A FILIP1L	9.27e-06	175	123	6	1799a7be623dc3bf53ba580a7c47d2619969d708
ToppCell	390C-Fibroblasts-Fibroblast-G\|390C / Donor, Lineage, Cell class and subclass (all cells)	MASP1 BMP5 DST PAPPA PDE5A PCOLCE	1.09e-05	180	123	6	137fc14859c89e1ecd98bee388bb58c04b835847
ToppCell	390C-Fibroblasts-Fibroblast-G-\|390C / Donor, Lineage, Cell class and subclass (all cells)	MASP1 BMP5 DST PAPPA PDE5A PCOLCE	1.09e-05	180	123	6	cd6790de050151fedfa2c5ea6ad58b72665414b2
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PAPPA2 RHOBTB3 SLCO4A1 DST GPC5 CCSER1	1.16e-05	182	123	6	a8cc56f32efe180e8fb5d69dbe606a794b3db700
ToppCell	E16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PAPPA2 MASP1 SFRP2 ZBTB7C RSPO3 PAPPA	1.16e-05	182	123	6	9966f42c338cbd471efa8ffc765a6ce93693aa75
ToppCell	LPS_only-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TCAF1 SPOCK1 RHOBTB3 ATRNL1 PAPPA PDE5A	1.19e-05	183	123	6	12daaea821e49bc94a01e2496331e92a80d27339
ToppCell	COPD-Myeloid-Macrophage_Alveolar\|World / Disease state, Lineage and Cell class	PDE8A MCF2L2 DST MITF CST3 CCSER1	1.23e-05	184	123	6	7fd0b227c3750ffb80e41e92c60fcce46656be14
ToppCell	Endothelial-Endothelial-E\|Endothelial / shred on cell class and cell subclass (v4)	SFRP2 VWF THSD7A FAM217A CST3 FILIP1L	1.39e-05	188	123	6	2777eb7689b271c199021fe7d9db88ccebff14de
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTSL1 SFRP2 ZBTB7C CCN5 RSPO3 LRFN5	1.39e-05	188	123	6	ce85a56ac27a6432421dde93a1bafa8b943244b9
ToppCell	Control-Fibroblasts-Adventitial_FB\|Control / group, cell type (main and fine annotations)	ADAMTSL1 SFRP2 SPOCK1 CCN5 LRFN5 PAPPA	1.39e-05	188	123	6	706a26c372add839d947749f0521a0e1f5c9b0ec
ToppCell	droplet-Lung-18m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ADAMTSL1 THSD7A RHOBTB3 FAM217A RSPO3 CCSER1	1.48e-05	190	123	6	e80d66ba0d5c263e94c1ab0b89d1dc7b837af3e1
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTSL1 RHOBTB3 JAK3 LRFN5 ATRNL1 NOTCH2	1.48e-05	190	123	6	1121eb607a984c59fbffe7220837fc178745aa55
ToppCell	droplet-Lung-18m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ADAMTSL1 THSD7A RHOBTB3 FAM217A RSPO3 CCSER1	1.48e-05	190	123	6	f32d66c0e74e0a2a23ecb857c4daf0d8573a806c
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTSL1 RHOBTB3 JAK3 LRFN5 ATRNL1 NOTCH2	1.48e-05	190	123	6	048b581e3f7ea9fc2f87c0532974bba85c7292c2
ToppCell	droplet-Lung-18m-Endothelial-lymphatic_endothelial\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ADAMTSL1 THSD7A RHOBTB3 FAM217A RSPO3 CCSER1	1.48e-05	190	123	6	b79ffd05806244a9790cd04c66fb4f92c824e69f
ToppCell	3'-Distal_airway-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.0.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SFRP2 CCN5 RSPO3 LRFN5 PAPPA PCOLCE	1.52e-05	191	123	6	f5ce33af56178333730be308253943c54a0724cf
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SFRP2 ZBTB7C SPOCK1 CCN5 RSPO3 LRFN5	1.52e-05	191	123	6	2c51850f5c559d665b8a27a12b75af9ed58dffe1
ToppCell	3'-Distal_airway-Mesenchymal-Fibroblastic-fibroblastic_type_1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SFRP2 CCN5 RSPO3 LRFN5 PAPPA PCOLCE	1.57e-05	192	123	6	a8b7c539dc3037071bf068f372e4215563e11de4
ToppCell	wk_08-11-Mesenchymal-Fibroblast-Mesenchymal_3\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	PAPPA2 ADAMTSL1 SFRP2 SPOCK1 RSPO3 FGF11	1.57e-05	192	123	6	d88753b200d9c8da6716222d697ddf0a1548d6c8
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ADAMTSL1 SFRP2 RSPO3 LRFN5 PAPPA PCOLCE	1.57e-05	192	123	6	e0f4e4470a71bfa81d9dcd8594e5f82aafc24f81
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts-Peribronchial_fibroblasts_L.2.1.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SFRP2 SPOCK1 CCN5 PDE5A FILIP1L PCOLCE	1.57e-05	192	123	6	c5f8e766453f87847b740d6988c524b3d0ef3765
ToppCell	Adult-Mesenchymal-matrix_fibroblast_2_cell\|Adult / Lineage, Cell type, age group and donor	ADAMTSL1 SFRP2 SPOCK1 ADAMTS10 CCN5 LRFN5	1.57e-05	192	123	6	d21f0f577156f17c899b08871046a26b88aea011
ToppCell	3'-Distal_airway-Mesenchymal-Fibroblastic\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SFRP2 CCN5 RSPO3 LRFN5 PAPPA PCOLCE	1.57e-05	192	123	6	2143e1fad2e88b90d668e12af37b2092d379090f
ToppCell	3'-Distal_airway-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SFRP2 CCN5 RSPO3 LRFN5 PAPPA PCOLCE	1.57e-05	192	123	6	904c003c4f73b1dfc8243cee02aad2676c515e50
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SFRP2 ZBTB7C SPOCK1 RSPO3 LRFN5 ATRNL1	1.62e-05	193	123	6	09a9ab029f01234459a88e3e994fe90ef4cbb8c6
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ADAMTSL1 SFRP2 RSPO3 LRFN5 PAPPA PCOLCE	1.62e-05	193	123	6	9ab47b360bee1d4f1092c2269e58acebe9584021
ToppCell	droplet-Fat-SCAT-30m-Mesenchymal-Cd34+\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYF5 ADAMTSL1 SFRP2 CCN5 NFIX PCOLCE	1.66e-05	194	123	6	588c45dafa00547b2506e298a2434b1b5e15560d
ToppCell	ASK428-Mesenchymal\|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq	SFRP2 CCN5 BMP5 PDE5A FILIP1L PCOLCE	1.71e-05	195	123	6	2b156163975d9a3d3fda1402acd9831d0fdc9e25
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ADAMTSL1 SFRP2 SPOCK1 CCN5 RSPO3 DST	1.71e-05	195	123	6	f54bc4454270ff06e85596f98199372b50d0179f
ToppCell	E12.5-Mesenchymal-mesenchymal_fibroblast-mesenchymal_alveolar_niche_cell\|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	ADAMTSL1 SFRP2 KLF4 RSPO3 NFIX CST3	1.71e-05	195	123	6	febe746099964b9ea9e75f2efc72c962c01f0421
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SFRP2 SPOCK1 BMP5 PDE5A FILIP1L PCOLCE	1.71e-05	195	123	6	1236dc60288c7dd91868e86e9174a2dacd3b11b3
ToppCell	ASK428-Mesenchymal-Fibroblast\|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq	SFRP2 CCN5 BMP5 PDE5A FILIP1L PCOLCE	1.71e-05	195	123	6	c269c0d894a0f55da6495b59d4b9abb9f68df684
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(CCL11+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RHOBTB3 BMP5 SALL1 PAPPA FILIP1L PCOLCE	1.76e-05	196	123	6	2ab9735aa7a7e95dcf6b0bdf0427f7b57f6349ee
ToppCell	nucseq-Mesenchymal-Fibroblastic\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	SFRP2 CCN5 BMP5 DST LRFN5 PCOLCE	1.76e-05	196	123	6	7d8505dac15fa59935ccf592afc54b04c4c6554f
ToppCell	368C\|World / Donor, Lineage, Cell class and subclass (all cells)	SFRP2 SPOCK1 CST3 PAPPA FILIP1L PCOLCE	1.81e-05	197	123	6	f41211923938e5d7bfe6bf24f604ab386f17ef10
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CCN5 BMP5 DST PDE5A FILIP1L PCOLCE	1.81e-05	197	123	6	94a9603cbd3516fbcce871909693b88f20d41713
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SFRP2 SPOCK1 CCN5 RSPO3 NFIX FILIP1L	1.81e-05	197	123	6	c747c496ac090309b7f8a3e9d840928f12c83f2f
ToppCell	PND14-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PAPPA2 ADAMTS10 BMP5 CST3 PDE5A FILIP1L	1.87e-05	198	123	6	ce59ee3d970397eb62d6387699c6c6cd65457898
ToppCell	10x5'v1-week_14-16-Myeloid_neutrophil-granulo-eo/baso/mast\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	REXO5 RHOBTB3 ALS2 TRIM64B MITF RAC2	1.87e-05	198	123	6	2e6630eab77b12a6059682ab5ba465f38e469102
ToppCell	3'-Child04-06-SmallIntestine-Mesenchymal-stromal_related-T_reticular\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MASP1 SFRP2 RSPO3 PDE5A FILIP1L PCOLCE	1.87e-05	198	123	6	5c96778cf5623c662c2259fe70f8665c14a161dd
ToppCell	nucseq-Mesenchymal\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	SFRP2 CCN5 BMP5 DST LRFN5 PCOLCE	1.87e-05	198	123	6	8f52243ca8b9ba68a75ae411506a3a6de258eb97
ToppCell	367C-Fibroblasts-Fibroblast-E-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	SFRP2 SPOCK1 CCN5 RSPO3 CST3 PCOLCE	1.92e-05	199	123	6	2aed8f4a225a3762a5e7ce99aacad9b2a37d61f1
ToppCell	368C-Fibroblasts-Fibroblast-D-\|368C / Donor, Lineage, Cell class and subclass (all cells)	SFRP2 SPOCK1 RSPO3 NFIX PAPPA PCOLCE	1.92e-05	199	123	6	5a425e7d11c5911ff5855c27a7f058a7ed7abbb0
ToppCell	367C-Fibroblasts-Fibroblast-E\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	SFRP2 SPOCK1 CCN5 RSPO3 CST3 PCOLCE	1.92e-05	199	123	6	c40ca26345753a2197bd9389d7323f7491c1e11d
ToppCell	368C-Fibroblasts-Fibroblast-D\|368C / Donor, Lineage, Cell class and subclass (all cells)	SFRP2 SPOCK1 RSPO3 NFIX PAPPA PCOLCE	1.92e-05	199	123	6	66545eb7f65e450b742628fd431956e13330a0d3
ToppCell	nucseq-Mesenchymal-Fibroblastic-Fibroblastic_1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ADAMTSL1 SFRP2 SPOCK1 CCN5 RSPO3 PCOLCE	1.92e-05	199	123	6	f835e7ffe976843b0edbf695762d463da85793f3
ToppCell	nucseq-Mesenchymal-Fibroblastic-Fibroblastic_1-AF2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ADAMTSL1 SFRP2 SPOCK1 CCN5 RSPO3 PCOLCE	1.92e-05	199	123	6	993fa050a095017135a6e723c77cd38b9d782e58
ToppCell	distal-2-mesenchymal-Myofibroblast\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	PAPPA2 SFRP2 CCN5 LRFN5 PAPPA PCOLCE	1.92e-05	199	123	6	b8f3cf5bcfde1066bdb49b14fdc842fe9692a6b7
ToppCell	ILEUM-non-inflamed-(8)_Fibroblast\|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	RHOBTB3 BMP5 DST PDE5A FILIP1L PCOLCE	1.92e-05	199	123	6	6a0df9a2f30480043f9c1d7fbdede17eb0910cac
ToppCell	5'-Adult-Distal_Rectal-Mesenchymal\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SFRP2 SPOCK1 CCN5 RSPO3 CST3 PCOLCE	1.97e-05	200	123	6	db6281b5d4032116310db379d9175d790994c99c
ToppCell	normal_Lung-Fibroblasts-COL14A1+_matrix_FBs\|Fibroblasts / Location, Cell class and cell subclass	SFRP2 KLF4 CCN5 RSPO3 CST3 PCOLCE	1.97e-05	200	123	6	6d8f6a6b3f61c529fbed1376659641030abf4f2c
ToppCell	Parenchyma_Control_(B.)-Stromal-TX-Fibroblasts-1\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	CEMIP CCN5 BMP5 DST PDE5A PCOLCE	1.97e-05	200	123	6	aa1a35dcca3b799241eef4237f6eb94660e019f0
ToppCell	Transplant_Alveoli_and_parenchyma-Mesenchymal\|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X	SFRP2 SPOCK1 CCN5 RSPO3 PAPPA PCOLCE	1.97e-05	200	123	6	954fee8425673e76198be414f5f6c4e3597c1919
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-3m-Neuroepithelial-Proteoglycan-expressing_cell\|3m / Sample Type, Dataset, Time_group, and Cell type.	SFRP2 KLF4 BMP5 PDE5A FILIP1L PCOLCE	1.97e-05	200	123	6	94ef227b2162ba77af33b8cc8aaa4a7e3bdf79a7
ToppCell	Lung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-1\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	CEMIP CCN5 BMP5 DST PDE5A PCOLCE	1.97e-05	200	123	6	a510deaada669e690329183e18df02870bd204b3
ToppCell	Parenchymal-10x5prime-Stromal-Fibroblastic\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	SFRP2 CCN5 RSPO3 BMP5 PAPPA PCOLCE	1.97e-05	200	123	6	6e3d1ae0ef84d3075afa40129a41169996462672
ToppCell	5'-Adult-Distal_Rectal-Mesenchymal-fibroblastic\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SFRP2 SPOCK1 CCN5 RSPO3 CST3 PCOLCE	1.97e-05	200	123	6	10f0c20ba7c71d9e2e177597f85b41cb40f0d878
ToppCell	distal-mesenchymal-Myofibroblast\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	PAPPA2 SFRP2 CCN5 PAPPA FILIP1L PCOLCE	1.97e-05	200	123	6	61854a459385cd9295be37157a8f81a2c227dff3
ToppCell	Parenchymal-10x3prime_v2-Stromal\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	SFRP2 CCN5 DST CST3 FILIP1L PCOLCE	1.97e-05	200	123	6	f6be0f24e607abb9007823a54fb0b24d04990a89
ToppCell	Tracheal-10x3prime_v2-Stromal\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	SFRP2 SPOCK1 CCN5 RSPO3 FILIP1L PCOLCE	1.97e-05	200	123	6	f74b9b0e27afedd589e828d30194e8417029817a
ToppCell	Skin-Fibroblasts\|Skin / Skin and Kidney Cells in Lupus Nephritis Patients.	MASP1 SFRP2 SPOCK1 ADAMTS10 CCN5 PCOLCE	1.97e-05	200	123	6	f777eadf571a1a6d246da87346a9cb9d511c2e81
Disease	hematologic cancer (implicated_via_orthology)	PIAS1 JAK1 JAK3	1.60e-05	13	115	3	DOID:2531 (implicated_via_orthology)
Disease	Congenital dyserythropoietic anemia, type I	CDAN1 SEC23B	8.99e-05	4	115	2	C0271933
Disease	Congenital dyserythropoietic anemia, type II	CDAN1 SEC23B	8.99e-05	4	115	2	C1306589
Disease	Congenital dyserythropoietic anemia, type III	CDAN1 SEC23B	1.49e-04	5	115	2	C0271934
Disease	Congenital dyserythropoietic anemia	CDAN1 SEC23B	1.49e-04	5	115	2	C0002876
Disease	Pigmentation Disorders	MASP1 MITF	1.49e-04	5	115	2	C0549567
Disease	Incontinentia Pigmenti Achromians	MASP1 MITF	1.49e-04	5	115	2	C0022283
Disease	Schamberg Disease	MASP1 MITF	1.49e-04	5	115	2	C0036305
Disease	diffuse plaque measurement	ADAMTSL1 SFRP2 ZBTB7C PDE8A RHOBTB3 TEKT5 BMP2 TMEM9 MITF KAT6B CCSER1	1.89e-04	758	115	11	EFO_0010699
Disease	Congenital dyserythropoietic anemia	CDAN1 SEC23B	2.24e-04	6	115	2	cv:C0002876
Disease	disease of cellular proliferation (implicated_via_orthology)	JAK1 JAK3	3.12e-04	7	115	2	DOID:14566 (implicated_via_orthology)
Disease	Lymphoma	JAK3 NOTCH2 RAC2	5.13e-04	40	115	3	C0024299
Disease	cancer (implicated_via_orthology)	SIN3A LCK AXIN2 DST FECH NOTCH2	6.54e-04	268	115	6	DOID:162 (implicated_via_orthology)
Disease	cortical surface area measurement	ADAMTSL1 SFRP2 GLS2 PDE8A CUL9 HMGCR ARHGAP39 RSPO3 BMP2 HAUS4 NFIX SYT4 PAPPA QSER1	7.56e-04	1345	115	14	EFO_0010736
Disease	Congenital Abnormality	KLF4 SALL1	8.09e-04	11	115	2	C0000768
Disease	T-cell acute lymphoblastic leukemia (is_implicated_in)	JAK1 JAK3	8.09e-04	11	115	2	DOID:5603 (is_implicated_in)
Disease	glycerophosphorylcholine measurement	JAK1 CCSER1	8.09e-04	11	115	2	EFO_0020018
Disease	Malignant neoplasm of breast	SFRP2 VWF MCF2L2 MDM4 ZDHHC4 RSPO3 BMP2 PER3 BRCA1 KAT6B NOTCH2 RAC2	1.00e-03	1074	115	12	C0006142
Disease	cerebellar volume measurement	MCHR2 RSPO3 PAPPA	1.11e-03	52	115	3	EFO_0020864
Disease	iron deficiency anemia (biomarker_via_orthology)	IREB2 CST3	1.14e-03	13	115	2	DOID:11758 (biomarker_via_orthology)
Disease	pre-eclampsia (implicated_via_orthology)	PDE5A NOTCH2	1.14e-03	13	115	2	DOID:10591 (implicated_via_orthology)
Disease	Abnormality of refraction	ADAMTSL1 THSD7A MCHR2 AXIN2 BMP2 LRFN5 NFIX C6 SEC23B	1.30e-03	673	115	9	HP_0000539
Disease	intracranial aneurysm (is_marker_for)	VWF CST3	1.33e-03	14	115	2	DOID:10941 (is_marker_for)
Disease	chronic obstructive pulmonary disease	ADAMTSL1 SFRP2 PPP1R3B RHOBTB3 IREB2 TEKT5 RSPO3 RNF220 QSER1	1.52e-03	688	115	9	EFO_0000341
Disease	Neoplasm of uncertain or unknown behavior of bladder	MDM4 NOTCH2	1.53e-03	15	115	2	C0496930
Disease	hepatoblastoma (is_marker_for)	AXIN2 SALL1	1.53e-03	15	115	2	DOID:687 (is_marker_for)
Disease	Benign neoplasm of bladder	MDM4 NOTCH2	1.53e-03	15	115	2	C0154017
Disease	Carcinoma in situ of bladder	MDM4 NOTCH2	1.53e-03	15	115	2	C0154091
Disease	RS-warfarin measurement	ZNF142 MCF2L2 LINC00469 KLF4	1.61e-03	128	115	4	EFO_0803325
Disease	Precursor Cell Lymphoblastic Leukemia Lymphoma	JAK1 JAK3 NOTCH2	1.76e-03	61	115	3	C1961102
Disease	nose morphology measurement	SFRP2 AXIN2 ADAMTS10 BMP2 SYT4 FILIP1L	1.87e-03	329	115	6	EFO_0007843
Disease	Carcinoma of bladder	MDM4 NOTCH2	2.21e-03	18	115	2	C0699885
Disease	carotid artery disease (is_marker_for)	VWF PAPPA	2.47e-03	19	115	2	DOID:3407 (is_marker_for)
Disease	Juvenile Myelomonocytic Leukemia	JAK3 RAC2	2.47e-03	19	115	2	C0349639
Disease	Meningioma	KLF4 CST3	2.47e-03	19	115	2	C0025286
Disease	unipolar depression, memory performance, cognitive function measurement	TET1 GPC5	2.73e-03	20	115	2	EFO_0003761, EFO_0004874, EFO_0008354
Disease	end stage renal disease (implicated_via_orthology)	HMGCR C6	2.73e-03	20	115	2	DOID:783 (implicated_via_orthology)
Disease	waist-hip ratio	PAPPA2 GLS2 ZBTB7C CUL9 CFAP65 CEMIP ADAMTS10 RSPO3 BMP2 NFIX SYT4 PDE5A	3.02e-03	1226	115	12	EFO_0004343

Protein segments in the cluster

Peptide	Gene	Start	Entry
QCLCPSLTIPNAKDV	AEN	11	Q8WTP8
KRKILCCITPQAPQC	ANKRD11	2451	Q6UB99
KPVPERCNQCSQLLI	ALS2	226	Q96Q42
EVSKPPKQRCCVASQ	AXIN2	706	Q9Y2T1
ICPVLKQCTNPKLNE	LINC00469	81	Q8N7U9
KTCQLPSLCLSNFLK	CCSER1	781	Q9C0I3
SVNSKIPKACCVPTE	BMP2	351	P12643
VLPCRSCAPNQVKVA	CEMIP	456	Q8WUJ3
KSPRCAQVPTKCSQS	DISP2	391	A7MBM2
KERSKQLQQSPTPTC	CDAN1	256	Q8IWY9
KLPKRQRACNTEPCP	ADAMTS10	871	Q9H324
PLPVCKQLCTERQKS	RANBP2	516	P49792
RSSLCKVKIVCPPQS	RAB40AL	251	P0C0E4
NLSKRKCPSQPVRAA	PCOLCE	431	Q15113
VLCPQPTRQQKRACS	RAC2	176	P15153
VCSKKPRNKPSQTIR	QSER1	1441	Q2KHR3
LPFPVCKQLCTERQK	RGPD5	516	Q99666
LPFPVCKQLCTERQK	RGPD8	516	O14715
SPCQQLVLTKQKCPE	ARHGAP39	366	Q9C0H5
KRCCQPKPREISNLL	JAK1	541	P23458
VQPKKLPCRGQTTCR	IREB2	161	P48200
LTSCCIPRPKEKSNL	JAK3	471	P52333
CKITPSARKPLCNRV	NPIPA1	201	Q9UND3
PSCLKFCPELTTNVK	KAT6B	246	Q8WYB5
PKRCVCQILSPNLAT	LRFN5	21	Q96NI6
KSLTPALCRTPANKL	MELK	406	Q14680
QCPKCAPAQKRLAKV	ANKRD27	716	Q96NW4
SDATPCKTPKQLLCR	TENT4B	461	Q8NDF8
CKTPKQLLCRPSTGN	TENT4B	466	Q8NDF8
QTLVNLCSRSPCKNK	NOTCH2	1061	Q04721
PRTCPKIKQEAVSSC	KLF4	271	O43474
LKRCTTTNPNQRLPK	MYF5	106	P13349
PCCVLSNPDQKGKIR	NFIX	101	Q14938
PRKPCNCTKSLCLKL	LIN54	521	Q6MZP7
QNLLKPCSLCEKRPR	MDM4	431	O15151
QLLKNCSKLPCLQVG	EURL	271	Q9NYK6
PHPKLCTRKNCNPLT	ERVS71-1	176	P61550
RKNKCVCDIPTPLQT	GGNBP2	381	Q9H3C7
PDLQVCISKKPTCCT	GPC5	56	P78333
RPSPRLLCTATKQKN	GRPEL1	21	Q9HAV7
QLKPRNSDCPLKTSI	DST	876	Q03001
SPVVTQKKVPDNCCR	HMGCR	356	P04035
PRSQDTICLTACPKQ	CFAP65	1056	Q6ZU64
NLQTARVKRCPPSKK	CDCA8	136	Q53HL2
LCRQPKPSTVQACNR	ADAMTSL1	711	Q8N6G6
SCIQEPATKCPNSKL	MCF2L2	266	Q86YR7
NIPALKRKCISCTNT	PER3	551	P56645
QCIRSLLCTPIKNGK	PDE5A	446	O76074
NCLAPRQKTSLKKAC	PGLYRP4	196	Q96LB8
LIKCADVSNPCRPLQ	PDE8A	721	O60658
LKNNSQCPACRVPIT	OBI1	46	Q5W0B1
LCTRLSRPCQTQKPQ	LCK	216	P06239
TKIPFCLQSCVKPLT	GLS2	211	Q9UI32
CKITPSARKPLCNRV	NPIPA3	201	F8WFD2
STADTPLCLQCKPLK	PAPPA	871	Q13219
QKQLCRPLTCEKSKP	NOP14	746	P78316
CPRGTKSLCQKQLLI	FGF11	31	Q92914
VIKLKRTPLCATAPC	KCTD18	376	Q6PI47
CCNPSVPKQRVMKLT	MCHR2	236	Q969V1
LKRCSISCVPPAKLQ	PAPPA2	1486	Q9BXP8
LLNQKKGPSQCPLCK	BRCA1	51	P38398
LTPSSKKPVRVCDAC	EEA1	1391	Q15075
IAKLLQQCTTRTPCP	BTAF1	901	O14981
QQCTTRTPCPNSKII	BTAF1	906	O14981
RTPCPNSKIIKNLCS	BTAF1	911	O14981
STSKCVCLLPPQCFK	C6	876	P13671
SFKCSQSTPCPVNRK	FILIP1L	846	Q4L180
LPDKSLINCTNRLPK	C9orf43	101	Q8TAL5
KPDCKSSPITRICAQ	IGFL4	96	Q6B9Z1
CLLSKVRTQLCPTPC	CCN5	16	O76076
VVSPNQNARPCKKPC	ATRNL1	876	Q5VV63
QNARPCKKPCSLRTS	ATRNL1	881	Q5VV63
KPCCAPTKLNAISVL	BMP5	416	P22003
SNKIPTCKIVDCRAP	MASP1	356	P48740
LISKRCPSCQAPIEK	CUL9	2231	Q8IWT3
SKQLTLSCPLCVNPV	FECH	396	P22830
TATGQRTCAKPCQKP	H1-9P	101	P60008
RTCAKPCQKPSTSKV	H1-9P	106	P60008
LQQVCSKQLPPCNLS	HAUS4	16	Q9H6D7
RQPKLCDSLSLQIPC	FAM217A	331	Q8IXS0
PLRVQHSCPICQKKF	SALL1	761	Q9NSC2
QPSSPSCVRQKVLKC	IPO13	211	O94829
RTTCTKTQPNLDNCP	CST3	96	P01034
SKPLRPCIQLSSKNE	PPP1R3B	31	Q86XI6
ILKTPGKINCLRNCK	RHOBTB3	381	O94955
CKITPSARKPLCNRV	NPIPA7	201	E9PJI5
CKITPSARKPLCNRV	NPIPA8	201	P0DM63
IKKCPVRPPSCASKQ	PKP1	196	Q13835
ICCQRKSSKSNKTPP	SYT4	36	Q9H2B2
KRSNCKPIPANLQLC	SFRP2	36	Q96HF1
LKLCTGPIPNTTQLC	THSD7A	491	Q9UPZ6
PLVINRCCLDKPTKS	TCAF1	591	Q9Y4C2
CKITPSARKPLCNRV	NPIPA5	201	E9PKD4
PLPVCKRLCTERQKS	RGPD2	516	P0DJD1
PKTGNCSVSRVKQCL	NAGPA	416	Q9UK23
CSVSRVKQCLQPPEA	NAGPA	421	Q9UK23
LTQTRKTCPICKQPV	RNF167	261	Q9H6Y7
QQPKCTGRTPLCKEV	SIN3A	566	Q96ST3
KKCCGLTSLPAVQAP	TEKT5	16	Q96M29
DSTNRKPLTKSQPCL	SECISBP2L	531	Q93073
RTLGAKKLCPQCNTI	RNF220	541	Q5VTB9
KKLCPQCNTITAPGD	RNF220	546	Q5VTB9
PPNLCVKVNTKPCSL	PIAS1	216	O75925
LRKKEASPPSNKLCC	SERTAD4	336	Q9NUC0
CSRPTCKAVLNPLCQ	SEC23B	61	Q15437
TAGKCTSTCQRKPLL	SLCO4A1	566	Q96BD0
PKLNHCPSLEKQSSC	TET1	951	Q8NFU7
TQKTKTSCAKCPPNA	ADGRE3	21	Q9BY15
LCCAVATAPKLKPVN	C10orf82	56	Q8WW14
PSSLCGKLKQALKPC	ZBTB48	186	P10074
NLNKKIPTIVRPCEC	ZNF564	91	Q8TBZ8
LQKKINDFCRSQCPP	UBA6	166	A0AVT1
NKSSEDIRCKCICPP	TMEM9	21	Q9P0T7
GRKVNCTTQPCPTAK	VWF	2286	P04275
CPANLPNIKRELTAC	MITF	281	O75030
PSSRNCQTIKCLSNK	REXO5	446	Q96IC2
SLKNANTCPTCRKKI	RNF4	166	P78317
PKNVRCSTCDLRKPA	ZDHHC4	146	Q9NPG8
KALPSPQKTNPCEIC	ZNF256	81	Q9Y2P7
PKKACPCASSAQVLQ	TNR	121	Q92752
CDQCNSKRRKSNPKP	USP49	516	Q70CQ1
SNLVKCKPCPVAQSA	SPOCK1	131	Q08629
KGNLCPPTNETRKCT	RSPO3	186	Q9BXY4
NPRIFILPSGKCCNK	ROS1	1046	P08922
RKLKPKASQQCPICH	ZBTB7C	356	A1YPR0
VQKQKGARFSCPTCP	ZNF142	1096	P52746
ALLKLCQPFCKPRSS	UBE4A	441	Q14139
RCPLCRKISEKPNFN	TRIM64C	51	A6NLI5
RCPSCRKISEKPNFN	TRIM64	51	A6NGJ6
RCPSCRKTSEKPNFN	TRIM64B	51	A6NI03
LTRRSPTCPVCKKTL	ZNF296	226	Q8WUU4
EKQLCQLPSPLCLSS	UNQ6126/PRO20091	91	Q6UXV3
PICPLCKAKSRSRNP	ZC4H2	201	Q9NQZ6
PNPANICVACLRSKV	NMD3	26	Q96D46