Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyCellularComponent	extracellular matrix	ADAMTS19 IL16 PRTN3 SVEP1 HMCN2 ADAMTS17 USH2A COL6A2 LAMB4 ZAN LAMA3 LAMA4 ADAMTS12 LRRN3 EYS ELANE MUC2 INS-IGF2 ADAMTSL2	1.49e-04	656	233	19	GO:0031012
GeneOntologyCellularComponent	external encapsulating structure	ADAMTS19 IL16 PRTN3 SVEP1 HMCN2 ADAMTS17 USH2A COL6A2 LAMB4 ZAN LAMA3 LAMA4 ADAMTS12 LRRN3 EYS ELANE MUC2 INS-IGF2 ADAMTSL2	1.55e-04	658	233	19	GO:0030312
HumanPheno	Cerebellar dentate nucleus calcification	ERCC6 MYORG ERCC8 SLC20A2	2.00e-06	7	81	4	HP:0002461
HumanPheno	Cerebellar calcifications	ERCC6 MYORG ERCC8 SLC20A2	1.16e-05	10	81	4	HP:0007352
Domain	WD40/YVTN_repeat-like_dom	SEMA3G ERCC8 SEMA5B FBXW5 PWP2 STRN4 WDR90 HERC1 SPAG16 WDR17 SEMA4B AMBRA1 WDPCP RFWD3 ARHGEF10L MST1R WDR87 WDR86 LRBA	3.70e-08	335	230	19	IPR015943
Domain	TF_AP2	TFAP2E TFAP2D TFAP2A TFAP2B	1.11e-07	5	230	4	IPR004979
Domain	TF_AP2_C	TFAP2E TFAP2D TFAP2A TFAP2B	1.11e-07	5	230	4	IPR013854
Domain	TF_AP-2	TFAP2E TFAP2D TFAP2A TFAP2B	1.11e-07	5	230	4	PF03299
Domain	WD40_repeat_dom	ITFG2 GTF3C4 ERCC8 FBXW5 PWP2 STRN4 WDR90 HERC1 SPAG16 WDR17 AMBRA1 WDPCP RFWD3 ARHGEF10L WDR87 WDR86 LRBA	1.74e-07	297	230	17	IPR017986
Domain	-	SEMA3G ERCC8 SEMA5B FBXW5 STRN4 WDR90 HERC1 SPAG16 WDR17 SEMA4B AMBRA1 WDPCP RFWD3 ARHGEF10L MST1R WDR87 WDR86 LRBA	1.76e-07	333	230	18	2.130.10.10
Domain	Quinoprotein_ADH-like_supfam	PWP2 WDR90 WDR17 FAM234B ERN2 WDR87 WDR86	3.73e-06	53	230	7	IPR011047
Domain	WD_REPEATS_1	ERCC8 FBXW5 PWP2 STRN4 WDR90 HERC1 SPAG16 WDR17 AMBRA1 WDPCP RFWD3 WDR87 WDR86 LRBA	9.55e-06	278	230	14	PS00678
Domain	WD_REPEATS_2	ERCC8 FBXW5 PWP2 STRN4 WDR90 HERC1 SPAG16 WDR17 AMBRA1 WDPCP RFWD3 WDR87 WDR86 LRBA	9.95e-06	279	230	14	PS50082
Domain	WD_REPEATS_REGION	ERCC8 FBXW5 PWP2 STRN4 WDR90 HERC1 SPAG16 WDR17 AMBRA1 WDPCP RFWD3 WDR87 WDR86 LRBA	9.95e-06	279	230	14	PS50294
Domain	WD40	ERCC8 FBXW5 PWP2 STRN4 WDR90 HERC1 SPAG16 WDR17 AMBRA1 RFWD3 WDR87 WDR86 LRBA	2.07e-05	259	230	13	PF00400
Domain	WD40	ERCC8 FBXW5 PWP2 STRN4 WDR90 HERC1 SPAG16 WDR17 AMBRA1 RFWD3 WDR87 WDR86 LRBA	2.95e-05	268	230	13	SM00320
Domain	WD40_repeat	ERCC8 FBXW5 PWP2 STRN4 WDR90 HERC1 SPAG16 WDR17 AMBRA1 RFWD3 WDR87 WDR86 LRBA	3.44e-05	272	230	13	IPR001680
Domain	PLAC	ADAMTS19 ADAMTS17 ADAMTS12 ADAMTSL2	7.51e-05	19	230	4	PS50900
Domain	PLAC	ADAMTS19 ADAMTS17 ADAMTS12 ADAMTSL2	7.51e-05	19	230	4	IPR010909
Domain	Phos_transporter	SLC20A1 SLC20A2	1.51e-04	2	230	2	IPR001204
Domain	Fzo_mitofusin	MFN2 MFN1	1.51e-04	2	230	2	PF04799
Domain	Mitofusin_fam	MFN2 MFN1	1.51e-04	2	230	2	IPR027094
Domain	PHO4	SLC20A1 SLC20A2	1.51e-04	2	230	2	PF01384
Domain	Fzo/mitofusin_HR2	MFN2 MFN1	1.51e-04	2	230	2	IPR006884
Domain	ADAM_spacer1	ADAMTS19 ADAMTS17 ADAMTS12 ADAMTSL2	1.65e-04	23	230	4	IPR010294
Domain	ADAM_spacer1	ADAMTS19 ADAMTS17 ADAMTS12 ADAMTSL2	1.65e-04	23	230	4	PF05986
Domain	-	SVEP1 USH2A LAMA3 LAMA4 EYS LGALS13 LRBA	1.73e-04	95	230	7	2.60.120.200
Domain	Peptidase_M12B_ADAM-TS	ADAMTS19 ADAMTS17 ADAMTS12 ADAMTSL2	1.96e-04	24	230	4	IPR013273
Domain	WD40_repeat_CS	ERCC8 PWP2 STRN4 WDR90 HERC1 SPAG16 WDR17 AMBRA1 WDR86	2.02e-04	164	230	9	IPR019775
Domain	Sushi	CD55 CSMD3 SVEP1 CSMD1 SEZ6L	4.40e-04	52	230	5	PF00084
Domain	EGF_LAM_2	USH2A LAMB4 LAMA3 LAMA4	4.77e-04	30	230	4	PS50027
Domain	EGF_LAM_1	USH2A LAMB4 LAMA3 LAMA4	4.77e-04	30	230	4	PS01248
Domain	PP2Ac	PPP2CA PPP2CB PPP4C	4.81e-04	13	230	3	SM00156
Domain	Ser/Thr-sp_prot-phosphatase	PPP2CA PPP2CB PPP4C	4.81e-04	13	230	3	IPR006186
Domain	SER_THR_PHOSPHATASE	PPP2CA PPP2CB PPP4C	4.81e-04	13	230	3	PS00125
Domain	CCP	CD55 CSMD3 SVEP1 CSMD1 SEZ6L	5.25e-04	54	230	5	SM00032
Domain	Semap_dom	SEMA3G SEMA5B SEMA4B MST1R	5.43e-04	31	230	4	IPR001627
Domain	SEMA	SEMA3G SEMA5B SEMA4B MST1R	5.43e-04	31	230	4	PS51004
Domain	Sema	SEMA3G SEMA5B SEMA4B MST1R	5.43e-04	31	230	4	SM00630
Domain	Sema	SEMA3G SEMA5B SEMA4B MST1R	5.43e-04	31	230	4	PF01403
Domain	PLAC	ADAMTS19 ADAMTS17 ADAMTSL2	6.07e-04	14	230	3	PF08686
Domain	Plexin_repeat	SEMA3G SEMA5B SEMA4B MST1R	6.15e-04	32	230	4	IPR002165
Domain	PSI	SEMA3G SEMA5B SEMA4B MST1R	6.15e-04	32	230	4	PF01437
Domain	SUSHI	CD55 CSMD3 SVEP1 CSMD1 SEZ6L	6.21e-04	56	230	5	PS50923
Domain	G-protein_beta_WD-40_rep	ERCC8 PWP2 STRN4 SPAG16 WDR17 WDR86	6.35e-04	85	230	6	IPR020472
Domain	Sushi_SCR_CCP_dom	CD55 CSMD3 SVEP1 CSMD1 SEZ6L	6.74e-04	57	230	5	IPR000436
Domain	EGF_Lam	USH2A LAMB4 LAMA3 LAMA4	8.69e-04	35	230	4	SM00180
Domain	Laminin_EGF	USH2A LAMB4 LAMA3 LAMA4	8.69e-04	35	230	4	PF00053
Domain	Pecanex_C	PCNX3 PCNX4	8.91e-04	4	230	2	PF05041
Domain	Pecanex	PCNX3 PCNX4	8.91e-04	4	230	2	IPR007735
Domain	Laminin_N	USH2A LAMB4 LAMA3	9.17e-04	16	230	3	IPR008211
Domain	LamNT	USH2A LAMB4 LAMA3	9.17e-04	16	230	3	SM00136
Domain	LAMININ_NTER	USH2A LAMB4 LAMA3	9.17e-04	16	230	3	PS51117
Domain	Laminin_N	USH2A LAMB4 LAMA3	9.17e-04	16	230	3	PF00055
Domain	TSP_1	ADAMTS19 SEMA5B ADAMTS17 ADAMTS12 ADAMTSL2	1.07e-03	63	230	5	PF00090
Domain	LAM_G_DOMAIN	USH2A LAMA3 LAMA4 EYS	1.19e-03	38	230	4	PS50025
Domain	Laminin_EGF	USH2A LAMB4 LAMA3 LAMA4	1.19e-03	38	230	4	IPR002049
Domain	TSP1	ADAMTS19 SEMA5B ADAMTS17 ADAMTS12 ADAMTSL2	1.23e-03	65	230	5	SM00209
Domain	TSP1_rpt	ADAMTS19 SEMA5B ADAMTS17 ADAMTS12 ADAMTSL2	1.23e-03	65	230	5	IPR000884
Domain	TSP1	ADAMTS19 SEMA5B ADAMTS17 ADAMTS12 ADAMTSL2	1.23e-03	65	230	5	PS50092
Domain	Laminin_G_2	USH2A LAMA3 LAMA4 EYS	1.45e-03	40	230	4	PF02210
Domain	Anaphylatoxin_comp_syst	C4A C4B	1.47e-03	5	230	2	IPR018081
Domain	Laminin_domII	LAMA3 LAMA4	1.47e-03	5	230	2	IPR010307
Domain	Anaphylatoxn_comp_syst_dom	C4A C4B	1.47e-03	5	230	2	IPR001840
Domain	Laminin_aI	LAMA3 LAMA4	1.47e-03	5	230	2	IPR009254
Domain	Laminin_I	LAMA3 LAMA4	1.47e-03	5	230	2	PF06008
Domain	Laminin_II	LAMA3 LAMA4	1.47e-03	5	230	2	PF06009
Domain	ConA-like_dom	SVEP1 HERC1 USH2A ZAN LAMA3 LAMA4 EYS LGALS13 LRBA	1.62e-03	219	230	9	IPR013320
Domain	HEAT_REPEAT	CAND1 BRAT1 RELCH MROH2B HTT	1.71e-03	70	230	5	PS50077
Domain	TRYPSIN_HIS	PRSS8 PRTN3 CTRB2 PRSS35 ELANE CTRB1	1.73e-03	103	230	6	IPR018114
Domain	Semaphorin	SEMA3G SEMA5B SEMA4B	1.80e-03	20	230	3	IPR027231
Domain	TRYPSIN_SER	PRSS8 PRTN3 CTRB2 PRSS35 ELANE CTRB1	2.00e-03	106	230	6	PS00135
Domain	PSI	SEMA3G SEMA5B SEMA4B MST1R	2.07e-03	44	230	4	IPR016201
Domain	LamG	USH2A LAMA3 LAMA4 EYS	2.07e-03	44	230	4	SM00282
Domain	TRYPSIN_HIS	PRSS8 PRTN3 CTRB2 PRSS35 ELANE CTRB1	2.10e-03	107	230	6	PS00134
Domain	PQQ	ERN2 WDR86	2.19e-03	6	230	2	SM00564
Domain	PQQ_beta_propeller_repeat	ERN2 WDR86	2.19e-03	6	230	2	IPR018391
Domain	-	FAM234B ERN2	2.19e-03	6	230	2	2.140.10.10
Domain	Quinoprotein_ADH-like_fam	FAM234B ERN2	2.19e-03	6	230	2	IPR027295
Domain	PSI	SEMA3G SEMA5B SEMA4B MST1R	2.44e-03	46	230	4	SM00423
Domain	TRYPSIN_DOM	PRSS8 PRTN3 CTRB2 PRSS35 ELANE CTRB1	3.01e-03	115	230	6	PS50240
Domain	ANATO	C4A C4B	3.04e-03	7	230	2	SM00104
Domain	ANAPHYLATOXIN_2	C4A C4B	3.04e-03	7	230	2	PS01178
Domain	ANAPHYLATOXIN_1	C4A C4B	3.04e-03	7	230	2	PS01177
Domain	ANATO	C4A C4B	3.04e-03	7	230	2	PF01821
Domain	Anaphylatoxin/fibulin	C4A C4B	3.04e-03	7	230	2	IPR000020
Pathway	REACTOME_NEGATIVE_REGULATION_OF_ACTIVITY_OF_TFAP2_AP_2_FAMILY_TRANSCRIPTION_FACTORS	TFAP2E TFAP2D TFAP2A TFAP2B	2.29e-06	9	167	4	MM15509
Pathway	REACTOME_NEGATIVE_REGULATION_OF_ACTIVITY_OF_TFAP2_AP_2_FAMILY_TRANSCRIPTION_FACTORS	TFAP2E TFAP2D TFAP2A TFAP2B	3.77e-06	10	167	4	M27764
Pathway	REACTOME_COBALAMIN_CBL_VITAMIN_B12_TRANSPORT_AND_METABOLISM	CTRB2 AMN MMAA CTRB1 MMAB	4.92e-06	22	167	5	M27084
Pathway	REACTOME_ACTIVATION_OF_THE_TFAP2_AP_2_FAMILY_OF_TRANSCRIPTION_FACTORS	TFAP2E TFAP2D TFAP2A TFAP2B	5.88e-06	11	167	4	MM15510
Pathway	REACTOME_ACTIVATION_OF_THE_TFAP2_AP_2_FAMILY_OF_TRANSCRIPTION_FACTORS	TFAP2E TFAP2D TFAP2A TFAP2B	8.73e-06	12	167	4	M27765
Pathway	REACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS	ADAMTS19 SEMA5B ADAMTS17 ADAMTS12 ADAMTSL2	9.13e-05	39	167	5	M27417
Pathway	REACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS	ADAMTS19 SEMA5B ADAMTS17 ADAMTS12 ADAMTSL2	9.13e-05	39	167	5	MM15165
Pathway	REACTOME_METABOLISM_OF_WATER_SOLUBLE_VITAMINS_AND_COFACTORS	NMNAT2 CTRB2 AMN FPGS MMAA MTHFR CTRB1 MMAB	1.33e-04	127	167	8	M27093
Pathway	REACTOME_UPTAKE_OF_DIETARY_COBALAMINS_INTO_ENTEROCYTES	CTRB2 AMN CTRB1	1.84e-04	10	167	3	M45024
Pathway	REACTOME_DISEASES_OF_METABOLISM	ADAMTS19 B4GALT7 CYP24A1 SEMA5B ADAMTS17 ALG1 AMN ADAMTS12 MMAA MMAB ADAMTSL2	1.94e-04	250	167	11	M27554
Pathway	REACTOME_TRANSCRIPTIONAL_REGULATION_BY_THE_AP_2_TFAP2_FAMILY_OF_TRANSCRIPTION_FACTORS	TFAP2E TFAP2D TFAP2A TFAP2B	2.32e-04	26	167	4	MM15502
Pathway	REACTOME_O_LINKED_GLYCOSYLATION	ADAMTS19 SEMA5B ADAMTS17 ADAMTS12 MUC2 GALNT4 ADAMTSL2	3.12e-04	109	167	7	MM15164
Pathway	WP_VITAMIN_B12_DISORDERS	AMN MMAA MMAB	4.28e-04	13	167	3	M39778
Pathway	REACTOME_DEFECTS_IN_COBALAMIN_B12_METABOLISM	AMN MMAA MMAB	5.40e-04	14	167	3	M27242
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	VWA5B2 PCNX3 OBSCN MED14 TRMT11 ANKHD1 TRRAP MYORG GGT7 PROM2 KCNG1 RRP12 SEC16A STRN4 MFN2 WDR90 HERC1 BRAT1 METTL27 PKN3 SEMA4B AMBRA1 BAHD1 ARHGEF10L MST1R GAS2L1 PPP2CB MTHFR PCNX4 LRBA HTT	3.35e-11	1105	238	31	35748872
Pubmed	Analysis of transcription factor AP-2 expression and function during mouse preimplantation development.	TFAP2E TFAP2D TFAP2A TFAP2B	1.06e-08	5	238	4	16672719
Pubmed	AP-2α and AP-2β regulate dorsal interneuron specification in the spinal cord.	TFAP2E TFAP2D TFAP2A TFAP2B	1.06e-08	5	238	4	27984181
Pubmed	Conditional deletion of activating protein 2alpha (AP-2alpha) in the developing retina demonstrates non-cell-autonomous roles for AP-2alpha in optic cup development.	TFAP2E MKI67 TFAP2D TFAP2A TFAP2B	1.77e-08	13	238	5	17724084
Pubmed	Cloning and characterization of the mouse AP-2 epsilon gene: a novel family member expressed in the developing olfactory bulb.	TFAP2E TFAP2D TFAP2A TFAP2B	7.36e-08	7	238	4	14572467
Pubmed	AP-2ε Expression in Developing Retina: Contributing to the Molecular Diversity of Amacrine Cells.	TFAP2E TFAP2D TFAP2A TFAP2B	7.36e-08	7	238	4	29467543
Pubmed	AP2gamma regulates basal progenitor fate in a region- and layer-specific manner in the developing cortex.	TFAP2E MKI67 TFAP2D TFAP2A TFAP2B	8.42e-07	26	238	5	19749747
Pubmed	Expression of Tfap2d, the gene encoding the transcription factor Ap-2 delta, during mouse embryogenesis.	TFAP2D TFAP2A TFAP2B	1.26e-06	4	238	3	12711551
Pubmed	CSA and CSB proteins interact with p53 and regulate its Mdm2-dependent ubiquitination.	CAND1 ERCC6 ERCC8 CUL4B	2.03e-06	14	238	4	22032989
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	B4GALT7 TM9SF3 CD55 LRRC59 MYORG GGT7 IGSF10 MEST MRC2 RRP12 C4A ALCAM USP48 SUCO ALG1 PCSK9 SEMA4B FAM234B STIM2 MBOAT7 LAMA4 MST1R GALNT4 HTT	3.06e-06	1201	238	24	35696571
Pubmed	The novel function of HINFP as a co-activator in sterol-regulated transcription of PCSK9 in HepG2 cells.	SREBF2 TRRAP PCSK9	3.13e-06	5	238	3	22288532
Pubmed	SMYD3 Impedes Small Cell Lung Cancer Sensitivity to Alkylation Damage through RNF113A Methylation-Phosphorylation Cross-talk.	CAND1 LRRC59 ANKHD1 GTF3C4 RRP12 SEC16A MKI67 HSD17B4 ILVBL MBOAT7 DSP AMBRA1 DNAJA3 PPP2CA PPP4C ANKRD17 RAVER1	3.23e-06	655	238	17	35819319
Pubmed	Global loss of leucine carboxyl methyltransferase-1 causes severe defects in fetal liver hematopoiesis.	MKI67 PPP2CA PPP2CB	6.23e-06	6	238	3	29735529
Pubmed	Alpha 4 associates with protein phosphatases 2A, 4, and 6.	PPP2CA PPP2CB PPP4C	6.23e-06	6	238	3	9647778
Pubmed	Loss of AP-2delta reduces retinal ganglion cell numbers and axonal projections to the superior colliculus.	TFAP2D TFAP2A TFAP2B	6.23e-06	6	238	3	27259519
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	ERCC6 OBSCN TRRAP SPATA31A6 GTF3C4 TRANK1 RRP12 C4A C4B HERC1 SPG11 PPP4C LRBA DNPEP	9.77e-06	497	238	14	36774506
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	SREBF2 ANKHD1 TTLL12 LPIN1 C4A C4B HSD17B4 ILVBL ALG1 COL6A2 AMBRA1 RFWD3 TMEM177 ANKRD17 ZBED1 RAVER1	1.22e-05	650	238	16	38777146
Pubmed	O-fucosylation of thrombospondin type 1 repeats restricts epithelial to mesenchymal transition (EMT) and maintains epiblast pluripotency during mouse gastrulation.	ADAMTS19 SEMA5B ADAMTS17 AMN ADAMTS12 ADAMTSL2	1.31e-05	75	238	6	20637190
Pubmed	Co-adaptor driven assembly of a CUL3 E3 ligase complex.	CAND1 PHKA1 AGL SEC16A	1.42e-05	22	238	4	35120648
Pubmed	Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion.	OBSCN HEPACAM2 IGSF10 ALCAM SEMA4B VSTM2A IGDCC4 LRRN3	1.71e-05	162	238	8	25826454
Pubmed	Mouse-human orthology relationships in an olfactory receptor gene cluster.	OR1A2 OR1A1 OR1E3	1.73e-05	8	238	3	11170746
Pubmed	Negligible role of antibodies and C5 in pregnancy loss associated exclusively with C3-dependent mechanisms through complement alternative pathway.	CD55 C4A C4B	1.73e-05	8	238	3	14670299
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	NMNAT2 CAND1 ANKHD1 KLHL9 TRANK1 SEMA5B MRC2 WDR90 RELCH AMBRA1 SPG11 BAHD1 ARHGEF10L ANKRD17	1.95e-05	529	238	14	14621295
Pubmed	A gene-based risk score for lung cancer susceptibility in smokers and ex-smokers.	NAT1 IL16 ERCC6 NAA80 MTHFR POLI ELANE	2.10e-05	121	238	7	19789190
Pubmed	The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.	IL16 HMCN2 ADAMTS17 COL6A2 LAMA3 LAMA4 ELANE MUC2	2.13e-05	167	238	8	22159717
Pubmed	CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment.	CAND1 GTF3C4 AGL RRP12 STRN4 BRAT1 ILVBL ALG1 PKN3 CUL4B FPGS AMBRA1 DNAJA3 PPP2CA PPP2CB	2.14e-05	606	238	15	36538041
Pubmed	Onecut1 and Onecut2 play critical roles in the development of the mouse retina.	C4A C4B TFAP2A TFAP2B	3.32e-05	27	238	4	25313862
Pubmed	Complement Inhibitor CRIg/FH Ameliorates Renal Ischemia Reperfusion Injury via Activation of PI3K/AKT Signaling.	C5AR2 C4A C4B	3.66e-05	10	238	3	30429287
Pubmed	High-throughput analysis of the C4 polymorphism by a combination of MLPA and isotype-specific ELISA's.	C4A C4B	4.66e-05	2	238	2	19062096
Pubmed	Mitofusins modulate the increase in mitochondrial length, bioenergetics and secretory phenotype in therapy-induced senescent melanoma cells.	MFN2 MFN1	4.66e-05	2	238	2	31431479
Pubmed	A human specific Alu DNA cassette is found flanking the genes of transcription factor AP2.	TFAP2D TFAP2B	4.66e-05	2	238	2	30975199
Pubmed	Sodium-dependent phosphate cotransporters and phosphate-induced calcification of vascular smooth muscle cells: redundant roles for PiT-1 and PiT-2.	SLC20A1 SLC20A2	4.66e-05	2	238	2	23968976
Pubmed	Antigen-induced B cell apoptosis is independent of complement C4.	C4A C4B	4.66e-05	2	238	2	17645767
Pubmed	Anti-DNA autoreactivity in C4-deficient mice.	C4A C4B	4.66e-05	2	238	2	12207352
Pubmed	A new mitofusin topology places the redox-regulated C terminus in the mitochondrial intermembrane space.	MFN2 MFN1	4.66e-05	2	238	2	29212658
Pubmed	Complement C4A and C4B Gene Copy Number Study in Alzheimer's Disease Patients.	C4A C4B	4.66e-05	2	238	2	27758680
Pubmed	AP-2α/AP-2β Transcription Factors Are Key Regulators of Epidermal Homeostasis.	TFAP2A TFAP2B	4.66e-05	2	238	2	38237728
Pubmed	Genome-wide methylation association with current suicidal ideation in schizophrenia.	SLC20A1 SMPD2	4.66e-05	2	238	2	32661777
Pubmed	Molecular genetics of androgen-dependent and -independent expression of mouse sex-limited protein.	C4A C4B	4.66e-05	2	238	2	3037333
Pubmed	Serum IL-16, not IL-15, was elevated in early second trimester of pregnancy in women who subsequently developed preeclampsia.	IL15 IL16	4.66e-05	2	238	2	17537415
Pubmed	Evidence of a role for C4 in modulating interstitial inflammation in experimental glomerulonephritis.	C4A C4B	4.66e-05	2	238	2	11726230
Pubmed	Quantitative variations in the expression of the mouse serum antigen Ss and its sex-limited allotype Slp.	C4A C4B	4.66e-05	2	238	2	4216347
Pubmed	Two highly conserved glutamate residues critical for type III sodium-dependent phosphate transport revealed by uncoupling transport function from retroviral receptor function.	SLC20A1 SLC20A2	4.66e-05	2	238	2	12205090
Pubmed	A large-scale transcriptome analysis identified ELANE and PRTN3 as novel methylation prognostic signatures for clear cell renal cell carcinoma.	PRTN3 ELANE	4.66e-05	2	238	2	31490025
Pubmed	Regulation of spindle formation by active mitogen-activated protein kinase and protein phosphatase 2A during mouse oocyte meiosis.	PPP2CA PPP2CB	4.66e-05	2	238	2	11751260
Pubmed	Tissue-specific RNA processing for the complement C4 gene transcript in the H-2k mouse strain.	C4A C4B	4.66e-05	2	238	2	8428773
Pubmed	NETosis-associated serum biomarkers are reduced in type 1 diabetes in association with neutrophil count.	PRTN3 ELANE	4.66e-05	2	238	2	26939803
Pubmed	Complement C4 deficiency--a plausible risk factor for non-tuberculous mycobacteria (NTM) infection in apparently immunocompetent patients.	C4A C4B	4.66e-05	2	238	2	24638111
Pubmed	Transcriptional repression of C4 complement by hepatitis C virus proteins.	C4A C4B	4.66e-05	2	238	2	21345967
Pubmed	Functional and clinical relevance of novel mutations in a large cohort of patients with Cockayne syndrome.	ERCC6 ERCC8	4.66e-05	2	238	2	29572252
Pubmed	Loss of mitofusin 2 promotes endoplasmic reticulum stress.	MFN2 MFN1	4.66e-05	2	238	2	22511781
Pubmed	The complement component C4 of mammals.	C4A C4B	4.66e-05	2	238	2	2302180
Pubmed	Gene CNVs and protein levels of complement C4A and C4B as novel biomarkers for partial disease remissions in new-onset type 1 diabetes patients.	C4A C4B	4.66e-05	2	238	2	22151770
Pubmed	Comprehensive approach to study complement C4 in systemic lupus erythematosus: Gene polymorphisms, protein levels and functional activity.	C4A C4B	4.66e-05	2	238	2	29080553
Pubmed	Epistatic SNP interaction of ERCC6 with ERCC8 and their joint protein expression contribute to gastric cancer/atrophic gastritis risk.	ERCC6 ERCC8	4.66e-05	2	238	2	28562347
Pubmed	Mitofusin 2 tethers endoplasmic reticulum to mitochondria.	MFN2 MFN1	4.66e-05	2	238	2	19052620
Pubmed	Natural killer cell expression of Ki67 is associated with elevated serum IL-15, disease activity and nephritis in systemic lupus erythematosus.	IL15 MKI67	4.66e-05	2	238	2	30693467
Pubmed	C4 Deficiency is a predisposing factor for Streptococcus pneumoniae-induced autoantibody production.	C4A C4B	4.66e-05	2	238	2	25339671
Pubmed	A study of association of the complement C4 mutations with systemic lupus erythematosus in the Malaysian population.	C4A C4B	4.66e-05	2	238	2	17728371
Pubmed	Genomic cloning and partial characterization of human chymotrypsinogen gene.	CTRB2 CTRB1	4.66e-05	2	238	2	8186414
Pubmed	Structure and organization of the C4 genes.	C4A C4B	4.66e-05	2	238	2	6149580
Pubmed	Sequence heterogeneity of murine complementary DNA clones related to the C4 and C4-Slp isoforms of the fourth complement component.	C4A C4B	4.66e-05	2	238	2	6149581
Pubmed	Cockayne Syndrome	ERCC6 ERCC8	4.66e-05	2	238	2	20301516
Pubmed	Biochemistry and biology of anaphylatoxins.	C4A C4B	4.66e-05	2	238	2	3542363
Pubmed	C4 from C4-high and C4-low mouse strains have identical sequences in the region corresponding to the isotype-specific segment of human C4.	C4A C4B	4.66e-05	2	238	2	2387317
Pubmed	MFN2 Hereditary Motor and Sensory Neuropathy	KIF1B MFN2	4.66e-05	2	238	2	20301684
Pubmed	Structural studies on the murine fourth component of complement (C4). IV. Demonstration that C4 and Slp are encoded by separate loci.	C4A C4B	4.66e-05	2	238	2	7365238
Pubmed	Peritubular capillary C4d deposition in lupus nephritis different from antibody-mediated renal rejection.	C4A C4B	4.66e-05	2	238	2	17971360
Pubmed	Adult skeletal muscle deletion of Mitofusin 1 and 2 impedes exercise performance and training capacity.	MFN2 MFN1	4.66e-05	2	238	2	30260752
Pubmed	Analysis of C4 and the C4 binding protein in the MRL/lpr mouse.	C4A C4B	4.66e-05	2	238	2	17971229
Pubmed	Multisystem analyses of two Cockayne syndrome associated proteins CSA and CSB reveal shared and unique functions.	ERCC6 ERCC8	4.66e-05	2	238	2	31546172
Pubmed	Elements That Regulate the DNA Damage Response of Proteins Defective in Cockayne Syndrome.	ERCC6 ERCC8	4.66e-05	2	238	2	26616585
Pubmed	Mitofusins are required for angiogenic function and modulate different signaling pathways in cultured endothelial cells.	MFN2 MFN1	4.66e-05	2	238	2	21839087
Pubmed	Plasma Complement 3 and Complement 4 Are Promising Biomarkers for Distinguishing NMOSD From MOGAD and Are Associated With the Blood-Brain-Barrier Disruption in NMOSD.	C4A C4B	4.66e-05	2	238	2	35898513
Pubmed	Protein phosphatase 2A and complement component 4 are linked to the protective effect of APOE ɛ2 for Alzheimer's disease.	C4A PPP2CB	4.66e-05	2	238	2	35142023
Pubmed	Borrelia burgdorferi outer surface protein C (OspC) binds complement component C4b and confers bloodstream survival.	C4A C4B	4.66e-05	2	238	2	28873507
Pubmed	Structural determinants of odorant recognition by the human olfactory receptors OR1A1 and OR1A2.	OR1A2 OR1A1	4.66e-05	2	238	2	17601748
Pubmed	Genomic organization and chromosomal localization of mouse proteinase 3 (Myeloblastin).	PRTN3 ELANE	4.66e-05	2	238	2	10051312
Pubmed	Structural basis of mitochondrial tethering by mitofusin complexes.	MFN2 MFN1	4.66e-05	2	238	2	15297672
Pubmed	Recombination of two homologous MHC class III genes of the mouse (C4 and Slp) that accounts for the loss of testosterone dependence of sex-limited protein expression.	C4A C4B	4.66e-05	2	238	2	3794341
Pubmed	Fine-tuned characterization of RCCX copy number variants and their relationship with extended MHC haplotypes.	C4A C4B	4.66e-05	2	238	2	22785613
Pubmed	Association between complement 4 copy number variation and systemic lupus erythematosus: a meta-analysis.	C4A C4B	4.66e-05	2	238	2	32691186
Pubmed	Mitochondrial toxic effects of Aβ through mitofusins in the early pathogenesis of Alzheimer's disease.	MFN2 MFN1	4.66e-05	2	238	2	24710686
Pubmed	Characterization of transport mechanisms and determinants critical for Na+-dependent Pi symport of the PiT family paralogs human PiT1 and PiT2.	SLC20A1 SLC20A2	4.66e-05	2	238	2	16790504
Pubmed	Negative feedback by IRE1β optimizes mucin production in goblet cells.	ERN2 MUC2	4.66e-05	2	238	2	23386727
Pubmed	The androgen-dependent C4-Slp gene is driven by a constitutively competent promoter.	C4A C4B	4.66e-05	2	238	2	8390682
Pubmed	Structure and expression of murine fourth complement component (C4) and sex-limited protein (Slp).	C4A C4B	4.66e-05	2	238	2	3902619
Pubmed	Association between common genetic variation in Cockayne syndrome A and B genes and nucleotide excision repair capacity among smokers.	ERCC6 ERCC8	4.66e-05	2	238	2	18708399
Pubmed	Structural polymorphism of murine C4 and its linkage to H-2.	C4A C4B	4.66e-05	2	238	2	7373044
Pubmed	Restriction fragment length polymorphism of the murine C4 and Slp genes: two C4 groups.	C4A C4B	4.66e-05	2	238	2	1357031
Pubmed	Cockayne Syndrome-Associated CSA and CSB Mutations Impair Ribosome Biogenesis, Ribosomal Protein Stability, and Global Protein Folding.	ERCC6 ERCC8	4.66e-05	2	238	2	34203326
Pubmed	Mitofusin1 in oocyte is essential for female fertility.	MFN2 MFN1	4.66e-05	2	238	2	30690319
Pubmed	Structural comparison of human C4A3 and C4B1 after proteolytic activation by C1s.	C4A C4B	4.66e-05	2	238	2	16098595
Pubmed	Increased frequency of C4B*Q0 alleles in patients with Henoch-Schönlein purpura.	C4A C4B	4.66e-05	2	238	2	15787745
Pubmed	The effect of gestational diabetes on the expression of mitochondrial fusion proteins in placental tissue.	MFN2 MFN1	4.66e-05	2	238	2	34600274
Pubmed	Neuropil contraction in relation to Complement C4 gene copy numbers in independent cohorts of adolescent-onset and young adult-onset schizophrenia patients-a pilot study.	C4A C4B	4.66e-05	2	238	2	30026462
Pubmed	A molecular map of the human major histocompatibility complex class III region linking complement genes C4, C2 and factor B.	C4A C4B	4.66e-05	2	238	2	6559257
Pubmed	Epigenetic programming of Dnmt3a mediated by AP2α is required for granting preadipocyte the ability to differentiate.	DNMT3A TFAP2A	4.66e-05	2	238	2	27906176
Pubmed	Compared action of neutrophil proteinase 3 and elastase on model substrates. Favorable effect of S'-P' interactions on proteinase 3 catalysts.	PRTN3 ELANE	4.66e-05	2	238	2	12538645
Pubmed	Polymerase chain reaction based C4AQ0 and C4BQ0 genotyping: association with systemic lupus erythematosus in southwest Han Chinese.	C4A C4B	4.66e-05	2	238	2	12480675
GeneFamily	WD repeat domain containing	ERCC8 FBXW5 PWP2 STRN4 WDR90 HERC1 SPAG16 WDR17 AMBRA1 RFWD3 WDR87 WDR86 LRBA	4.56e-07	262	156	13	362
GeneFamily	Hyalectan proteoglycans\|V-set domain containing\|Sushi domain containing\|C-type lectin domain containing	CD55 CSMD3 SVEP1 CSMD1 SEZ6L	1.31e-04	57	156	5	1179
GeneFamily	Laminin subunits	LAMB4 LAMA3 LAMA4	1.31e-04	12	156	3	626
GeneFamily	Protein phosphatase catalytic subunits\|EF-hand domain containing	PPP2CA PPP2CB PPP4C	1.69e-04	13	156	3	693
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	OBSCN HEPACAM2 IGSF10 HMCN2 IGDCC4 LRRN3 MUSK	5.00e-04	161	156	7	593
GeneFamily	ADAM metallopeptidases with thrombospondin type 1 motif	ADAMTS19 ADAMTS17 ADAMTS12	5.52e-04	19	156	3	50
GeneFamily	Protein phosphatase catalytic subunits\|STRIPAK complex	STRN4 PPP2CA PPP2CB	6.45e-04	20	156	3	1371
GeneFamily	Immunoglobulin like domain containing\|Semaphorins	SEMA3G SEMA5B SEMA4B	6.45e-04	20	156	3	736
GeneFamily	WD repeat domain containing\|ERCC excision repair associated	ERCC6 ERCC8	1.51e-03	7	156	2	1268
GeneFamily	C3 and PZP like, alpha-2-macroglobulin domain containing	C4A C4B	2.56e-03	9	156	2	1234
GeneFamily	Glycosyltransferase family 6\|Blood group antigens	CD55 C4A C4B	3.95e-03	37	156	3	454
GeneFamily	Olfactory receptors, family 1	OR1A2 OR1A1 OR1E3	4.93e-03	40	156	3	147
Coexpression	NABA_MATRISOME	VWA5B2 ADAMTS19 IL15 IL16 SEMA3G SVEP1 IGSF10 HMCN2 DHH SEMA5B ADAMTS17 USH2A COL6A2 SEMA4B LAMB4 LAMA3 LAMA4 ADAMTS12 EYS IL22 LGALS13 ELANE MUC2 CTSW INS-IGF2 ADAMTSL2	1.58e-06	1026	232	26	M5889
Coexpression	GSE411_UNSTIM_VS_100MIN_IL6_STIM_SOCS3_KO_MACROPHAGE_UP	TBC1D19 RPS6KA5 TRRAP AGL PWP2 STRN4 BRAT1 RELCH POLI SLC25A28	1.26e-05	200	232	10	M6004
Coexpression	GSE22103_UNSTIM_VS_GMCSF_AND_IFNG_STIM_NEUTROPHIL_UP	SLC25A46 RPS6KA5 LRRC59 TRRAP TACC1 HSD17B4 BRAT1 FAM234B GAS2L1 SLC20A2	1.26e-05	200	232	10	M7789
Coexpression	MASSARWEH_TAMOXIFEN_RESISTANCE_UP	SGMS2 TM9SF3 CD55 PROM2 SEC16A TACC1 WDR90 ALCAM FAM234B RELCH SFMBT2 MMAA ARFGEF3 TMEM45B SLC20A1 AGMAT MUC2	1.93e-05	583	232	17	M17454
Coexpression	SINGH_KRAS_DEPENDENCY_SIGNATURE	SEMA4B LAMA3 MST1R TMEM45B	2.59e-05	20	232	4	M2851
Coexpression	NABA_BASEMENT_MEMBRANES	USH2A COL6A2 LAMB4 LAMA3 LAMA4	2.66e-05	40	232	5	M5887
ToppCell	droplet-Kidney-nan-18m-Epithelial-Epcam____kidney_collecting_duct_principal_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRPM6 SGMS2 HEPACAM2 PROM2 FAM234B DSP VSTM2A TFAP2A TFAP2B TMEM45B	7.90e-08	190	237	10	d4910c37045a8b8bb53b37625263bc0a47b6e3f8
ToppCell	Entopeduncular-Endothelial-ENDOTHELIAL_TIP-Dcn_1\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	HMCN2 MRC2 COL6A2 PHETA2 TFAP2A TFAP2B WDR86 MUSK	3.88e-07	126	237	8	fe6900eb37e4f09465a1276586c73dd38545fa2a
ToppCell	Entopeduncular-Endothelial-ENDOTHELIAL_TIP\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	HMCN2 MRC2 COL6A2 PHETA2 TFAP2A TFAP2B WDR86 MUSK	3.88e-07	126	237	8	3d507f829882d043f633db2612b76936e2042445
ToppCell	Entopeduncular-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn_(Dcn)-\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	HMCN2 MRC2 COL6A2 PHETA2 TFAP2A TFAP2B WDR86 MUSK	3.88e-07	126	237	8	f1f24b06d301c266226d1a59dd28585f5ac68f29
ToppCell	Entopeduncular-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	HMCN2 MRC2 COL6A2 PHETA2 TFAP2A TFAP2B WDR86 MUSK	3.88e-07	126	237	8	1ac4cc747e466bc79e33b97608b19ad29a7a6a41
ToppCell	Entopeduncular-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn_(Dcn)\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	HMCN2 MRC2 COL6A2 PHETA2 TFAP2A TFAP2B WDR86 MUSK	3.88e-07	126	237	8	2de551d7a8765afec1da8852727c79fec90f45f8
ToppCell	droplet-Kidney-nan-18m-Epithelial-kidney_collecting_duct_principal_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRPM6 SGMS2 HEPACAM2 FAM234B DSP VSTM2A TFAP2A TFAP2B TMEM45B	8.61e-07	190	237	9	c408d4033a130c0168159a5b6f286fd2b2a9a39d
ToppCell	PBMC-Severe-Myeloid-Neutrophil-Neutrophil-Neu_4\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	PRTN3 PIDD1 NCBP1 AGL HERC3 NSUN6 SLC20A2 POLI ELANE	8.61e-07	190	237	9	3f0c7d130f66faea778fe567604edf1b4cdf85b3
ToppCell	PBMC-Severe-Myeloid-Neutrophil-Neutrophil-Neu_4\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	PRTN3 PIDD1 NCBP1 AGL HERC3 NSUN6 SLC20A2 POLI ELANE	9.40e-07	192	237	9	c09dcc73ff9c3855a0f3d7bfa0d5c99c09a117f2
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SVEP1 IGSF10 MRC2 ADAMTS17 NHS COL6A2 LAMA4 IGDCC4 ADAMTS12	1.02e-06	194	237	9	89b706af2b25991fc2707eb24f49ba6ff3ae01f7
ToppCell	Goblet\|World / shred by cell class for turbinate	PRSS8 TM9SF3 CD55 LRRC59 HEPACAM2 BPIFA1 ALCAM ERN2 MUC2	1.02e-06	194	237	9	03b62e7cff5e7a6e7bd7d9dda273c74bf9c1f42e
ToppCell	PCW_13-14-Epithelial-Epithelial_airway\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	SGMS2 PRSS8 CD55 PKHD1 ALCAM DSP LAMA3 RAB11FIP1 ARFGEF3	1.02e-06	194	237	9	7b2b40a56eb9c7203ca50133b2da4fd8fdd4a5cf
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SVEP1 IGSF10 MRC2 COL6A2 LAMA4 ADAMTS12 LRRN3 MUSK ADAMTSL2	1.07e-06	195	237	9	df409f94f4e83be89f7a608058ee07ce3ce3a149
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SVEP1 IGSF10 MRC2 COL6A2 LAMA4 ADAMTS12 LRRN3 MUSK ADAMTSL2	1.07e-06	195	237	9	4243190ad291d56694e2155954dbaa879c9d3844
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SVEP1 IGSF10 MRC2 COL6A2 LAMA4 ADAMTS12 LRRN3 MUSK ADAMTSL2	1.12e-06	196	237	9	9737a5f006d37b549f281e1863aca558e1e4dc99
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SVEP1 IGSF10 MRC2 COL6A2 LAMA4 ADAMTS12 LRRN3 MUSK ADAMTSL2	1.12e-06	196	237	9	42e9828222a9663525d571633e8a454c30bfa7f8
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SVEP1 IGSF10 MRC2 COL6A2 LAMA4 ADAMTS12 LRRN3 MUSK ADAMTSL2	1.12e-06	196	237	9	cecf82cd5e0a3835d655f5e7478578674a63ce25
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SVEP1 IGSF10 MRC2 COL6A2 LAMA4 ADAMTS12 LRRN3 MUSK ADAMTSL2	1.16e-06	197	237	9	13896ec65ccda0b928c91d41112dc01b480036b7
ToppCell	PCW_13-14-Epithelial\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	SGMS2 PRSS8 CD55 PKHD1 ALCAM DSP LAMA3 RAB11FIP1 ARFGEF3	1.21e-06	198	237	9	48eb6f69a464a34ab32e8d425a22b9d45ec20428
ToppCell	PCW_10-12-Epithelial-Epithelial_airway\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	SGMS2 PRSS8 CD55 PKHD1 ALCAM DSP LAMA3 RAB11FIP1 ARFGEF3	1.21e-06	198	237	9	9a12e5e47236433e512c668005fe3f8be6fde95c
ToppCell	Tracheal-10x5prime-Stromal-Peri/Epineurial_-NAF_epineurial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	C5AR2 SEMA3G CSMD3 MRC2 C4B PCSK9 COL6A2 VSTM2A LRRN3	1.27e-06	199	237	9	fbec5c034576cb1adaf05f6f97cc5525d19e0c1b
ToppCell	356C-Myeloid-Macrophage-SPP1+_Macrophage\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	TBC1D19 ITFG2 ETFDH NAA80 GTF3C4 NHS COL6A2 FAM234B	2.84e-06	164	237	8	d6806deabf5f5c355934387be2baae125ac33fb8
ToppCell	facs-Marrow-T-cells-3m-Hematologic-MPP_Fraction_B_+_C\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ERCC6 TTLL12 KCNG1 AGXT BRAT1 FDXACB1 FAM234B PHETA2	3.70e-06	170	237	8	d70aaa0f4e5034bb9f61b832b5f9123870936d3c
ToppCell	facs-Lung-Endomucin_-18m-Myeloid-non-classical_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	C5AR2 ZC3H3 MKI67 ELAC1 RAB11FIP1 PHETA2 ARHGEF10L GPCPD1	4.22e-06	173	237	8	c31076c725f4cd912c56903592a2d9356ae59f54
ToppCell	facs-Lung-Endomucin_-18m-Myeloid-Nonclassical_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	C5AR2 ZC3H3 MKI67 ELAC1 RAB11FIP1 PHETA2 ARHGEF10L GPCPD1	4.22e-06	173	237	8	a4ed191cfdf6588b7f3672995bf0a4fe9e4b8df6
ToppCell	Globus_pallidus-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Apold1_(Pi16)--\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	SEMA3G DHH AGXT PKN3 DSP CTSW	4.35e-06	80	237	6	475e1595528aef08799f099d7dc54412eaa14742
ToppCell	Globus_pallidus-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Apold1_(Pi16)\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	SEMA3G DHH AGXT PKN3 DSP CTSW	4.35e-06	80	237	6	8713818f57f40c07268f791b45c8af6d522c628f
ToppCell	Globus_pallidus-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Apold1_(Pi16)-\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	SEMA3G DHH AGXT PKN3 DSP CTSW	4.35e-06	80	237	6	09baf1f1a4f07369af3696bc15d0ffcf89de984e
ToppCell	droplet-Fat-Scat-21m-Mesenchymal-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OBSCN ADAMTS17 COL6A2 PHETA2 GPR150 ABCB11 ADPRHL1 SBK3	5.20e-06	178	237	8	5fc9f41609735b972a2cd0830182d13742cd5bf5
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OBSCN CSMD3 TRANK1 PKHD1 USH2A ZAN ARFGEF3 CSMD1	6.64e-06	184	237	8	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OBSCN CSMD3 TRANK1 PKHD1 USH2A ZAN ARFGEF3 CSMD1	6.64e-06	184	237	8	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OBSCN CSMD3 TRANK1 PKHD1 USH2A ZAN ARFGEF3 CSMD1	6.64e-06	184	237	8	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	TRPM6 SGMS2 ESRRB MEST ADAMTS17 PKHD1 LAMB4 LAMA3	7.47e-06	187	237	8	77886f99c229610abd28c4c370d2c7d1536c9782
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SVEP1 IGSF10 MRC2 NHS COL6A2 LAMA4 IGDCC4 ADAMTS12	8.72e-06	191	237	8	b13229bb7f3713a392271aaf5dbae3edd1b9fe5a
ToppCell	PND01-03-samps-Mesenchymal-Matrix_fibroblast-MatrixFB-A\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	NMNAT2 SVEP1 MRC2 ADAMTS17 TACC1 COL6A2 ADAMTS12 ADAMTSL2	8.72e-06	191	237	8	e7c605b56934d1383237c1f946dbccef25d91368
ToppCell	PCW_13-14-Epithelial-Epithelial_neuroendo-epi_NE_progenitor_(7)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	PRSS8 CD55 PKHD1 ALCAM DSP LAMA3 ARFGEF3 TMEM45B	8.72e-06	191	237	8	63aa671837b79d2feb7ed1e67712cc01caf72bef
ToppCell	PCW_13-14-Epithelial-Epithelial_airway-epi_intermediate_(1)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	SGMS2 PRSS8 CD55 PKHD1 ALCAM DSP LAMA3 RAB11FIP1	9.06e-06	192	237	8	b73f24d1c55dfef1eb01c26da117dbf637ea080a
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Macroglial-astrocyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CLCN1 DENND4B HERC3 ANKRD35 PLEKHG4 GPR150 GALNT4	9.29e-06	138	237	7	6b83c434895d82eaf3c222eef27acec76f9c0a77
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	IL16 SVEP1 ADAMTS17 COL6A2 LAMA4 ADAMTS12 MUSK ADAMTSL2	9.41e-06	193	237	8	99525545552b371c86b18b6ea6f4897dc6e9a9ec
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	IL16 SVEP1 ADAMTS17 COL6A2 LAMA4 ADAMTS12 MUSK ADAMTSL2	9.77e-06	194	237	8	e93de9428c986b8943fc169258847c650cfab0e5
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SVEP1 IGSF10 MRC2 NHS COL6A2 LAMA4 IGDCC4 ADAMTS12	9.77e-06	194	237	8	60622bd2f75bfe4c37f721cb12f03dab33f2f58d
ToppCell	PCW_10-12-Epithelial-Epithelial_airway-epi_proximal_progenitor2_(4)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	SGMS2 CD55 PKHD1 ALCAM DSP LAMA3 RAB11FIP1 ARFGEF3	1.01e-05	195	237	8	d673f8844896d5c7b76a7bc7f6b88a039f1bc263
ToppCell	Adult-Mesenchymal-matrix_fibroblast_1_cell-D122\|Adult / Lineage, Cell type, age group and donor	IL16 SVEP1 IGSF10 COL6A2 LAMA4 ADAMTS12 MUSK ADAMTSL2	1.01e-05	195	237	8	aa0add081881d349099d12efca5cdee098038d4e
ToppCell	Substantia_nigra-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Gkn3_(Gkn3)\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	NAT1 SEMA3G DHH DSP LAMA3 SLC45A2	1.04e-05	93	237	6	312291db0fab96952017f9faf2057c28f3719556
ToppCell	Substantia_nigra-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Gkn3_(Gkn3)-\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	NAT1 SEMA3G DHH DSP LAMA3 SLC45A2	1.04e-05	93	237	6	4eca07c288fe15531a685522c61746671c1c87fb
ToppCell	Substantia_nigra-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Gkn3_(Gkn3)--\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	NAT1 SEMA3G DHH DSP LAMA3 SLC45A2	1.04e-05	93	237	6	8f65381291fc92b56bf0fc2caac013a54560737b
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CD55 BPIFA1 PROM2 ALCAM AMN DSP RAB11FIP1 ERN2	1.05e-05	196	237	8	a52879a4c822c5e4be569f01f845a795e00c5f4b
ToppCell	PCW_10-12-Epithelial\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	SGMS2 PRSS8 CD55 PKHD1 DSP LAMA3 RAB11FIP1 ARFGEF3	1.05e-05	196	237	8	9bfb31ff3e4f2c0a9405c418c86bfec5dbca23e2
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CD55 BPIFA1 PROM2 ALCAM AMN DSP RAB11FIP1 ERN2	1.05e-05	196	237	8	7a4d502550e9e37dc42f2ff1be3c896afe365d7f
ToppCell	normal_Lung-Fibroblasts-COL13A1+_matrix_FBs\|normal_Lung / Location, Cell class and cell subclass	SVEP1 IGSF10 MRC2 COL6A2 LAMA4 ADAMTS12 LRRN3 ADAMTSL2	1.09e-05	197	237	8	6c57ab2efb8363828e24211c4d45e58bb73a9a4d
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SVEP1 IGSF10 MRC2 COL6A2 LAMA4 ADAMTS12 LRRN3 MUSK	1.09e-05	197	237	8	94a9603cbd3516fbcce871909693b88f20d41713
ToppCell	cellseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	SVEP1 IGSF10 MRC2 COL6A2 LAMA4 ADAMTS12 LRRN3 MUSK	1.13e-05	198	237	8	f1374f7a50244d59c766ac41f44c08c9117407d2
ToppCell	COVID-19_Severe-Neu_4\|COVID-19_Severe / 5 Neutrophil clusters in COVID-19 patients	BRIP1 CAND1 PRTN3 NAA80 MKI67 SUCO RFWD3 ELANE	1.13e-05	198	237	8	bfdddddef9f3f0eb6af013873dec4e06b7c78c58
ToppCell	Bronchial-10x5prime-Stromal-Fibroblastic-Fibro_immune_recruiting\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	SVEP1 C4B COL6A2 LAMA3 LAMA4 ABCB11 MUSK ADAMTSL2	1.17e-05	199	237	8	0cdbedf09ec72734b86ddab3fec562e066afed92
ToppCell	kidney_cells-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SGMS2 PRSS8 TM9SF3 MYORG ALCAM DNMT3A CUL4B	1.28e-05	145	237	7	47a3bb973a508d3097213a2d86ad1ce697af9bae
ToppCell	Entopeduncular-Endothelial-ENDOTHELIAL_STALK-Flt1_1\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	DHH PKN3 LAMA3 SLC45A2 CTSW ADAMTSL2	1.77e-05	102	237	6	2c3622fc3cd62d9b7e185d0204cf7f03e7dde73c
ToppCell	Mild_COVID-19-Myeloid-TRAM2\|Mild_COVID-19 / Disease group,lineage and cell class （2021.01.30）	DENND4B RRP12 WDR17 PKN3 ZNF775 ZBTB47 GPCPD1	1.90e-05	154	237	7	ab648f6b29eb9e499e46cbdbaf3c5cf6b94d1f64
ToppCell	mild_COVID-19_(asymptomatic)-CD8+_T_naive\|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)	MRC2 SPAG16 FDXACB1 TBCCD1 TMEM177 LRRN3 EYS	1.98e-05	155	237	7	e2c901d5c9e42d25d7702e5e8fc19b06f7c817be
ToppCell	facs-Marrow-B-cells-3m-Lymphocytic-mature_alpha-beta_T_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	B4GALT7 RELCH BAHD1 MMAA TMEM177 SLC45A2 CTSW	2.42e-05	160	237	7	296e53e1e0786346d38db2d4188b9a1c0430627b
ToppCell	facs-Marrow-B-cells-3m-Lymphocytic-BM_CD8_+_CD4_T_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	B4GALT7 RELCH BAHD1 MMAA TMEM177 SLC45A2 CTSW	2.42e-05	160	237	7	55f599df6e3b7a5a505df4b094c834281311d94a
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-proliferative_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	BRIP1 SVEP1 MRC2 LAMA4 PHETA2 ADAMTS12 ADAMTSL2	2.63e-05	162	237	7	bfaeff19bb56598fdc8c82be71d51787cf13928f
ToppCell	LPS-IL1RA-Unknown-Endothelial-Monocytes-Macrophages\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PIDD1 STRN4 PRR14L ALCAM DSP POLI ADAMTSL2	2.73e-05	163	237	7	6b11a3ada8725670d0489f404c8c2175ad3904e9
ToppCell	TCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Mucinous_Colon_Adenocarcinoma\|TCGA-Colorectal / Sample_Type by Project: Shred V9	CD55 ALOX15B STIM2 CBFA2T3 TFAP2A FUT11 MUC2	2.84e-05	164	237	7	3c15e9b8403b03d67f6ecd7861dc19f1261e3244
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal-SPN_Neuron_STR\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRTN3 TRANK1 SEMA5B WDR17 PCSK9 ANKRD35 SLC32A1	2.95e-05	165	237	7	1b7dfa173e83aa8c46a3153a3261866c065c3b73
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal-medium_spiny_neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRTN3 TRANK1 SEMA5B WDR17 PCSK9 ANKRD35 SLC32A1	2.95e-05	165	237	7	b4f7d33af7d053ec07b01bd67d861600a9c4822e
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CYP24A1 CSMD3 ZAN EYS AGMAT CSMD1 SEZ6L	3.19e-05	167	237	7	3edb0570e583bb527165bcd8a4c25a042054043b
ToppCell	Substantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Gad2-Fos_(IEG_state,_GABAergic)-\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	ADAMTS19 HMCN2 PCSK9 TFAP2A TFAP2B	3.56e-05	70	237	5	e1ac00f4a519b6ada89f591e549874bd3eed0ca1
ToppCell	Substantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Gad2-Fos_(IEG_state,_GABAergic)--\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	ADAMTS19 HMCN2 PCSK9 TFAP2A TFAP2B	3.56e-05	70	237	5	27e12c0f43a996bcbed285c5ee668bef5a786d80
ToppCell	Substantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Gad2-Fos_(IEG_state,_GABAergic)\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	ADAMTS19 HMCN2 PCSK9 TFAP2A TFAP2B	3.56e-05	70	237	5	b6815131e87e81c10e65bc398a84dab5a74b32ac
ToppCell	5'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial-L_cells_(PYY+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	VWA5B2 CLCN1 PKHD1 DSP RAB11FIP1 ARFGEF3 EYS	3.57e-05	170	237	7	985c2d5962100fab0d95bee39f382ccbe799331e
ToppCell	COVID-19_Convalescent-cDC\|COVID-19_Convalescent / Disease condition and Cell class	NAA80 GGT7 ALCAM BRAT1 METTL27 CTSW SEZ6L	3.71e-05	171	237	7	9ccaa9f1629818b0f63a5d930ee78c01e04cd98d
ToppCell	COVID-19_Convalescent-cDC-\|COVID-19_Convalescent / Disease condition and Cell class	NAA80 GGT7 ALCAM BRAT1 METTL27 CTSW SEZ6L	3.71e-05	171	237	7	fb5fae8b3adafcbb7c5618d887966b418355ed4d
ToppCell	facs\|World / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TCAF1 B4GALT7 KLHL9 TACC1 PRR14L MUSK ADAMTSL2	3.85e-05	172	237	7	a2d0a64ebf09d219a07d6bbad1056bad6d46b9be
ToppCell	facs-Heart-Unknown-3m-Mesenchymal-atrial_myocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OBSCN CLCN1 AGXT DSP ASB14 ADPRHL1 SBK3	3.85e-05	172	237	7	ee8ce9e8c9a6d3ee2be113f77743958005f4b3f0
ToppCell	facs-Heart-Unknown-3m-Mesenchymal-atrial_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OBSCN CLCN1 AGXT DSP ASB14 ADPRHL1 SBK3	3.85e-05	172	237	7	bd468a7ea6ec832dcf6a816a1e0c03fa0f176dad
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-5w-Mesenchymal-Cilia-bearing_cell\|5w / Sample Type, Dataset, Time_group, and Cell type.	TTLL12 PWP2 CDNF FDXACB1 ERN2 ARHGEF10L TMEM177	3.99e-05	173	237	7	d4cbeae262abfa30d8c5452285d3261a96875610
ToppCell	5'-Adult-Distal_Rectal-Epithelial-goblet-BEST2+_Goblet_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TM9SF3 LRRC59 HEPACAM2 PCSK9 ERN2 ARFGEF3 MUC2	4.30e-05	175	237	7	019ea30ac55748463d7917abf3d3f0e804189bfd
ToppCell	nucseq-Epithelial-Epithelial_Airway-Secretory/RAS-Secretory\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CYP24A1 BPIFA1 PROM2 NHS ERN2 TFAP2A ARFGEF3	4.62e-05	177	237	7	0f210cfb61b873c5fd77dc17eadf4d017306500e
ToppCell	nucseq-Epithelial-Epithelial_Airway-Secretory/RAS\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CYP24A1 BPIFA1 PROM2 NHS ERN2 TFAP2A ARFGEF3	4.62e-05	177	237	7	779ba86f53650772755b52460be03f18bb204e55
ToppCell	5'-Adult-Distal_Rectal-Epithelial-goblet\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TM9SF3 LRRC59 HEPACAM2 PCSK9 ERN2 ARFGEF3 MUC2	4.79e-05	178	237	7	9099b47e0756d6a1b7ba1c6aa7b47c5425f649e0
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Macroglial-astrocyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AGL C4A C4B WDR90 SLC20A1 HTT	5.10e-05	123	237	6	a45d6907c041ad3f3218cd46dccfc25d4bd961cb
ToppCell	Control-Epithelial-Goblet\|Control / Disease state, Lineage and Cell class	CYP24A1 BPIFA1 PROM2 NHS ERN2 TFAP2A ARFGEF3	5.14e-05	180	237	7	5293d23b8b8ea587239ffde561b70bad01632521
ToppCell	facs-Marrow-Granulocytes-3m-Lymphocytic-mature_alpha-beta_T_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRRC59 GGT7 SACS PKHD1 TFAP2A TMEM177 NSUN6	5.32e-05	181	237	7	41969fe4d94ee77b12ecde32170aaf0b13e49644
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	IL16 SVEP1 IGSF10 LAMA4 ADAMTS12 LRRN3 MUSK	5.32e-05	181	237	7	9ede19228ba5c0668a9c06c915510b95585216ef
ToppCell	facs-Marrow-Granulocytes-3m-Lymphocytic-BM_CD8_+_CD4_T_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRRC59 GGT7 SACS PKHD1 TFAP2A TMEM177 NSUN6	5.32e-05	181	237	7	3f50e61dc2a52d71a5801584617607e6246adcf2
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Mesenchymal-cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OBSCN OSGEPL1 PRSS35 DSP ASB14 MFN1 ADPRHL1	5.51e-05	182	237	7	c4a7007c864a9455a7e7447e28ccd380878a6a0f
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Mesenchymal-atrial_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OBSCN OSGEPL1 PRSS35 DSP ASB14 MFN1 ADPRHL1	5.51e-05	182	237	7	c315d820ffad912c014ba5eac6f5fa6de1a94384
ToppCell	356C-Myeloid-Macrophage-SPP1+_Macrophage\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	TBC1D19 ITFG2 NAA80 NHS COL6A2 FAM234B	5.58e-05	125	237	6	43aa4b77dccf0ea2979218826af16034f2017c3a
ToppCell	PND07-28-samps-Epithelial\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	TRPM6 PRSS8 CD55 ALCAM DSP ZBBX ARFGEF3	5.70e-05	183	237	7	a98f1d71d82ed6cca996f74352ab834fb6e95206
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_VIP_PRSS8\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PRSS8 KCNG1 VSTM2A LAMA3 IGDCC4 SLC32A1 MROH2B	6.32e-05	186	237	7	fef543f188edb0d1704d9c6ace366a0f8017bf53
ToppCell	droplet-Kidney-KIDNEY-1m-Mesenchymal-fibroblast\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SVEP1 IGSF10 MRC2 ADAMTS17 COL6A2 IGDCC4 CSMD1	6.32e-05	186	237	7	94d577dbb6bfacf50632e1fe8af041b35a1e6b23
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SVEP1 IGSF10 MRC2 COL6A2 LAMA4 ADAMTS12 MUSK	6.32e-05	186	237	7	5473283fb95cee556b1f6934cf72169b676b5bcc
ToppCell	Control-Fibroblasts-Alveolar_FB\|Control / group, cell type (main and fine annotations)	IL16 SVEP1 ADAMTS17 LAMA4 ADAMTS12 MUSK ADAMTSL2	6.53e-05	187	237	7	92d468dde81125d51daf7abd4703741abe1ab91c
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_ADARB2_ADAM33\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	IL15 PRSS8 KCNG1 NHS VSTM2A IGDCC4 LRRN3	6.53e-05	187	237	7	02105c82a9ba79d2f19e002188377fc3440770c2
ToppCell	COVID-19-Epithelial_cells-Airway_basal\|COVID-19 / group, cell type (main and fine annotations)	TRPM6 CYP24A1 PROM2 NHS DSP TFAP2A ARFGEF3	6.53e-05	187	237	7	8407a82e98f56a94ea26562bcb6bbe00a8f41661
ToppCell	COVID-19-kidney-Mito-rich_Int\|kidney / Disease (COVID-19 only), tissue and cell type	CSMD3 SVEP1 DMC1 EYS CSMD1 CTRB1	6.65e-05	129	237	6	57b705106aec7bbfc587de1ccd4f2335fc44dd6f
ToppCell	PCW_10-12-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	SGMS2 PRSS8 PKHD1 ALCAM DSP LAMA3 ARFGEF3	6.75e-05	188	237	7	beb2df2332a46cc81b10e8e29fc9829020111f03
ToppCell	droplet-Kidney-KIDNEY-30m-Epithelial-Epcam_____kidney_distal_convoluted_tubule_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRPM6 SGMS2 PROM2 VSTM2A TFAP2A TFAP2B ARFGEF3	6.75e-05	188	237	7	ab6fa1beff91584d9303c2a33735de89aae8d5cd
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	IL16 SVEP1 TRANK1 HMCN2 MRC2 COL6A2 LAMA4	6.75e-05	188	237	7	ce85a56ac27a6432421dde93a1bafa8b943244b9
ToppCell	facs-Heart-LV-3m-Mesenchymal-ventricular_myocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ETFDH OBSCN AGL FBXW5 DSP ASB14 ADPRHL1	6.75e-05	188	237	7	40ce7125fca6f6b6b5cc1637c87d43c29b08f4f1
Drug	Dipyridamole [58-32-2]; Down 200; 8uM; MCF7; HT_HG-U133A	BRIP1 ITFG2 ETFDH LPIN1 RRP12 TACC1 DNMT3A DDX31 MBOAT7 RFWD3 DMC1 SMPD2	7.25e-07	192	233	12	1517_DN
Drug	3-amino-2-pyridone	CTRB2 ELANE CTRB1	1.06e-06	3	233	3	CID000322353
Drug	alpha-amyrin palmitate	CTRB2 ELANE CTRB1	4.20e-06	4	233	3	CID000185477
Drug	NSC-676827	CTRB2 ELANE CTRB1	4.20e-06	4	233	3	CID000385555
Drug	Z-Phe-Leu	CTRB2 ELANE CTRB1	1.04e-05	5	233	3	CID000333351
Drug	AC1L3F57	CTRB2 ELANE CTRB1	1.04e-05	5	233	3	CID000139565
Drug	Maap-borov	CTRB2 ELANE CTRB1	1.04e-05	5	233	3	CID005486914
Drug	HMP-P	TFAP2E TFAP2D TFAP2A TFAP2B	1.77e-05	16	233	4	CID000000216
Drug	2-amino-4-chloro-6-hydroxy-s-triazine	TFAP2E TFAP2D TFAP2A TFAP2B	1.77e-05	16	233	4	CID000430167
Drug	octyl isocyanate	CTRB2 ELANE CTRB1	2.07e-05	6	233	3	CID000076616
Drug	L-659,286	CTRB2 ELANE CTRB1	2.07e-05	6	233	3	CID000128954
Drug	Maap-borof	CTRB2 ELANE CTRB1	2.07e-05	6	233	3	CID005492190
Drug	cobalt;(6E)-6-[[2-[[(E)-(6-oxocyclohexa-2,4-dien-1-ylidene)methyl]amino]ethylamino]methylene]cyclohexa-2,4-dien-1-one;hydrate	CTRB2 ELANE CTRB1	2.07e-05	6	233	3	CID011810022
Drug	D-gluconyl-glycine azide	CTRB2 ELANE CTRB1	2.07e-05	6	233	3	CID000194550
Drug	bz-Ala-OMe	CTRB2 ELANE CTRB1	2.07e-05	6	233	3	CID000023671
Drug	AC1L4DZ7	CTRB2 ELANE CTRB1	2.07e-05	6	233	3	CID000155288
Drug	methylcyclopentadienyl manganese tricarbonyl	CTRB2 NHS ELANE CTRB1	2.29e-05	17	233	4	CID000025511
Drug	AC1L2TMY	PRTN3 CTRB2 ELANE CTRB1	2.29e-05	17	233	4	CID000102826
Drug	NSC 308880	TFAP2E TFAP2D TFAP2A TFAP2B	2.29e-05	17	233	4	CID000073599
Drug	3'-dCTP	TFAP2E MED14 C4A TFAP2D TFAP2A TFAP2B ELANE	3.90e-05	90	233	7	CID000153054
Drug	Methimazole [60-56-0]; Down 200; 35uM; PC3; HT_HG-U133A	PRSS8 PDE6C ITFG2 SREBF2 NAA80 PAOX MRC2 PRR14L ERN2 DNPEP	3.94e-05	198	233	10	4550_DN
Drug	AC1L1EJT	NCBP1 AMN MMAA OTC MTHFR MMAB	4.92e-05	64	233	6	CID000002823
Drug	cyclohexadiene	PPP4C POLI SLC45A2 SMPD2	5.58e-05	21	233	4	CID000011605
Drug	indium trihydride	CTRB2 ELANE CTRB1	5.70e-05	8	233	3	CID000024000
Drug	3-(4-sulfamoylphenyl)propanoic acid	CTRB2 ELANE CTRB1	5.70e-05	8	233	3	CID003161908
Drug	Z-Phe-OMC	CTRB2 ELANE CTRB1	5.70e-05	8	233	3	CID000127395
Drug	3,5-bis-trifluoromethylphenylboronic acid	CTRB2 LRBA CTRB1	5.70e-05	8	233	3	CID000156265
Drug	BOC-Ala-OMC	CTRB2 ELANE CTRB1	5.70e-05	8	233	3	CID000132159
Drug	2-methylproline	CTRB2 ELANE CTRB1	5.70e-05	8	233	3	CID000095491
Drug	boronic acids	CTRB2 PPP4C ELANE CTRB1	6.76e-05	22	233	4	CID000139619
Drug	N-carbobenzoxy-l-alanine	CTRB2 KCNG1 ELANE CTRB1	6.76e-05	22	233	4	CID000070832
Drug	Hydroxocobalamin	AMN MMAA MMAB	8.49e-05	9	233	3	DB00200
Drug	ZPCK	CTRB2 ELANE CTRB1	8.49e-05	9	233	3	CID000099625
Drug	pyrenebutyl methylphosphonofluoridate	CTRB2 ELANE CTRB1	8.49e-05	9	233	3	CID000125653
Drug	B316	CTRB2 AGXT CTRB1	8.49e-05	9	233	3	CID000199983
Drug	3-chloroisocoumarin	CTRB2 ELANE CTRB1	8.49e-05	9	233	3	CID000560737
Drug	delta(E)Phe	CTRB2 NHS CTRB1	8.49e-05	9	233	3	CID000133830
Drug	5-amino-2-nitrobenzoic acid	CTRB2 ELANE CTRB1	8.49e-05	9	233	3	CID000083298
Drug	AC1NRA23	PRSS8 CTRB2 C4A ELANE CTRB1 CTSW	1.03e-04	73	233	6	CID005287657
Drug	BOCPheONP	CTRB2 CTRB1	1.04e-04	2	233	2	CID000111308
Drug	MPM-06	CTRB2 CTRB1	1.04e-04	2	233	2	CID000161546
Drug	NSC-374899	CTRB2 CTRB1	1.04e-04	2	233	2	CID000435726
Drug	methylbenzenebutanoate	CTRB2 CTRB1	1.04e-04	2	233	2	CID000281254
Drug	Asp-Arg-Val-Tyr-Val-His-Pro-Phe-His-Leu	CTRB2 CTRB1	1.04e-04	2	233	2	CID004418081
Drug	c189	CTRB2 CTRB1	1.04e-04	2	233	2	CID000248048
Drug	dansyl-D-arginine methyl ester	CTRB2 CTRB1	1.04e-04	2	233	2	CID000191369
Drug	methyl 6-phenylhexanoate	CTRB2 CTRB1	1.04e-04	2	233	2	CID011820300
Drug	5-aminotetrazole	CTRB2 CTRB1	1.04e-04	2	233	2	CID000020467
Drug	2-bromoisobutyric acid	CTRB2 CTRB1	1.04e-04	2	233	2	CID000074924
Drug	p-toluamidine	CTRB2 CTRB1	1.04e-04	2	233	2	CID000122753
Drug	Antibodies, Antineutrophil Cytoplasmic	PRTN3 ELANE	1.04e-04	2	233	2	ctd:D019268
Drug	N-acetyl-alpha-azaphenylalanine phenyl ester	CTRB2 CTRB1	1.04e-04	2	233	2	CID000191275
Drug	isobutyl sulfide	CTRB2 CTRB1	1.04e-04	2	233	2	CID000011607
Drug	azotochelin	ERCC6 PGBD3	1.04e-04	2	233	2	CID000193592
Drug	Pergolide mesylate [66104-23-2]; Down 200; 9.8uM; HL60; HT_HG-U133A	PRTN3 SEMA3G TTLL12 RRP12 PWP2 DDX31 ERN2 DNAJA3 PTRH2	1.08e-04	181	233	9	2403_DN
Drug	phthalimide	PRTN3 ILVBL PPP4C ELANE	1.14e-04	25	233	4	CID000006809
Drug	RD4-6205	CTRB2 ELANE CTRB1	1.20e-04	10	233	3	CID003002865
Drug	LY 294002; Up 200; 10uM; MCF7; HT_HG-U133A	TBC1D19 ERCC6 RPS6KA5 MED14 CD55 NAA80 TACC1 CUL4B ERN2	1.33e-04	186	233	9	1664_UP
Disease	sleep disorder (implicated_via_orthology)	TFAP2E TFAP2D TFAP2A TFAP2B	1.08e-06	11	227	4	DOID:535 (implicated_via_orthology)
Disease	Charcot-Marie-Tooth disease type 2A2A (implicated_via_orthology)	MFN2 MFN1	5.89e-05	2	227	2	DOID:0110155 (implicated_via_orthology)
Disease	Cockayne Syndrome, Type III	ERCC6 ERCC8	5.89e-05	2	227	2	C0751037
Disease	Charcot-Marie-Tooth disease, type 2A	KIF1B MFN2	5.89e-05	2	227	2	cv:C2079538
Disease	Cockayne syndrome	ERCC6 ERCC8	5.89e-05	2	227	2	cv:C0009207
Disease	Hereditary motor and sensory neuropathy with optic atrophy (disorder)	SLC25A46 MFN2	5.89e-05	2	227	2	C0393807
Disease	Cockayne syndrome (is_implicated_in)	ERCC6 ERCC8	5.89e-05	2	227	2	DOID:2962 (is_implicated_in)
Disease	Charcot-Marie-Tooth disease type 2A2B (implicated_via_orthology)	MFN2 MFN1	5.89e-05	2	227	2	DOID:0111557 (implicated_via_orthology)
Disease	level of chymotrypsinogen B2 in blood serum	CTRB2 CTRB1	5.89e-05	2	227	2	OBA_2041192
Disease	Colorectal Carcinoma	ERCC6 ETFDH OBSCN CSMD3 LPIN1 SACS MKI67 PKHD1 RELCH ZNF560 FPGS CBFA2T3 MFN1 ARHGEF10L MTHFR ABCB11	1.19e-04	702	227	16	C0009402
Disease	squamous cell carcinoma, multiple keratinocyte carcinoma susceptibility measurement, basal cell carcinoma	BRIP1 PKHD1 CSMD1	1.21e-04	13	227	3	EFO_0000707, EFO_0004193, EFO_0007932
Disease	Hereditary motor and sensory neuropathy with optic atrophy	SLC25A46 MFN2	1.76e-04	3	227	2	cv:C0393807
Disease	Cockayne Syndrome, Type II	ERCC6 ERCC8	1.76e-04	3	227	2	C0751038
Disease	Cockayne Syndrome, Type I	ERCC6 ERCC8	1.76e-04	3	227	2	C0751039
Disease	chymotrypsinogen B measurement	CTRB2 CTRB1	1.76e-04	3	227	2	EFO_0801477
Disease	UV-Sensitive Syndrome	ERCC6 ERCC8	1.76e-04	3	227	2	C1833561
Disease	UV-sensitive syndrome (is_implicated_in)	ERCC6 ERCC8	1.76e-04	3	227	2	DOID:0060240 (is_implicated_in)
Disease	Cockayne Syndrome	ERCC6 ERCC8	1.76e-04	3	227	2	C0009207
Disease	lipid metabolism disorder (implicated_via_orthology)	LPIN1 HSD17B4 MTHFR	1.91e-04	15	227	3	DOID:3146 (implicated_via_orthology)
Disease	lung cancer (is_marker_for)	ERCC6 CYP24A1 MKI67 DNMT3A	2.27e-04	39	227	4	DOID:1324 (is_marker_for)
Disease	Malignant neoplasm of breast	ADAMTS19 BRIP1 ERCC6 CYP24A1 OBSCN SREBF2 MED14 TRMT11 HEPACAM2 CLCN1 SEMA5B MKI67 NHS PGBD3 DNMT3A TFAP2D TFAP2A NSUN6 MTHFR LRBA	2.61e-04	1074	227	20	C0006142
Disease	Amphetamine-Related Disorders	PDE6C CD55 USP48 GRM2 CSMD1	2.87e-04	75	227	5	C0236733
Disease	Amphetamine Abuse	PDE6C CD55 USP48 GRM2 CSMD1	2.87e-04	75	227	5	C0236807
Disease	Amphetamine Addiction	PDE6C CD55 USP48 GRM2 CSMD1	2.87e-04	75	227	5	C0236804
Disease	Clinodactyly of fingers	TFAP2A TFAP2B	3.50e-04	4	227	2	C0265610
Disease	neutrophil elastase measurement	PRTN3 ELANE	3.50e-04	4	227	2	EFO_0020605
Disease	Charcot-Marie-Tooth disease type 2 (implicated_via_orthology)	MFN2 MFN1	3.50e-04	4	227	2	DOID:0050539 (implicated_via_orthology)
Disease	methylmalonic acidemia (implicated_via_orthology)	MMAA MMAB	3.50e-04	4	227	2	DOID:14749 (implicated_via_orthology)
Disease	Clinodactyly	TFAP2A TFAP2B	3.50e-04	4	227	2	C4551485
Disease	homocysteine measurement	MFN2 GTPBP10 MTHFR CSMD1	4.32e-04	46	227	4	EFO_0004578
Disease	Obsessive-compulsive trait	SGMS2 TRMT11 TMEM45B	5.39e-04	21	227	3	HP_0008770
Disease	mucositis (biomarker_via_orthology)	MKI67 MUC2	5.80e-04	5	227	2	DOID:0080178 (biomarker_via_orthology)
Disease	Fahr's syndrome (disorder)	MYORG SLC20A2	5.80e-04	5	227	2	C0393590
Disease	Methylmalonic acidemia	MMAA MMAB	5.80e-04	5	227	2	cv:C0268583
Disease	ovarian neoplasm	BRIP1 ERCC6 TRMT11 LRRC59 MKI67 GPR150	6.14e-04	134	227	6	C0919267
Disease	eye color	TRANK1 JAZF1 EYS SLC45A2 CSMD1	6.66e-04	90	227	5	EFO_0003949
Disease	Malignant neoplasm of ovary	BRIP1 ERCC6 TRMT11 LRRC59 MKI67 GPR150	6.90e-04	137	227	6	C1140680
Disease	level of Sphingomyelin (d40:2) in blood serum	PCSK9 ANKRD17 MUSK	7.10e-04	23	227	3	OBA_2045181
Disease	dietary heme iron intake measurement, type 2 diabetes mellitus	SVEP1 MUSK	8.66e-04	6	227	2	EFO_0008355, MONDO_0005148
Disease	level of Phosphatidylinositol (18:1_18:2) in blood serum	MBOAT7 MUSK	8.66e-04	6	227	2	OBA_2045160
Disease	basal ganglia calcification (is_implicated_in)	MYORG SLC20A2	8.66e-04	6	227	2	DOID:0060230 (is_implicated_in)
Disease	trypsin-1 measurement	CBFA2T3 CTRB1	8.66e-04	6	227	2	EFO_0020790
Disease	Cockayne syndrome (implicated_via_orthology)	ERCC6 ERCC8	8.66e-04	6	227	2	DOID:2962 (implicated_via_orthology)
Disease	level of Sterol ester (27:1/18:2) in blood serum	PCSK9 ANKRD17 MUSK	1.03e-03	26	227	3	OBA_2045194
Disease	X-24870 measurement	TMEM45B MUSK	1.21e-03	7	227	2	EFO_0022143
Disease	1-arachidonoyl-GPI (20:4) measurement	MBOAT7 MUSK	1.21e-03	7	227	2	EFO_0800256
Disease	1-linoleoyl-GPI (18:2) measurement	MBOAT7 MUSK	1.21e-03	7	227	2	EFO_0800266
Disease	level of Sphingomyelin (d36:2) in blood serum	ANKRD17 MUSK	1.21e-03	7	227	2	OBA_2045177
Disease	1-palmitoyl-2-linoleoyl-GPI (16:0/18:2) measurement	MBOAT7 MUSK	1.21e-03	7	227	2	EFO_0800609
Disease	lung small cell carcinoma (is_implicated_in)	CYP24A1 LAMA3 MTHFR	1.28e-03	28	227	3	DOID:5409 (is_implicated_in)
Disease	primary pulmonary hypertension (is_marker_for)	MFN2 MFN1	1.60e-03	8	227	2	DOID:14557 (is_marker_for)
Disease	periodontal disease (biomarker_via_orthology)	IL15 IL16	1.60e-03	8	227	2	DOID:3388 (biomarker_via_orthology)
Disease	Congenital Hand Deformities	TFAP2B ADAMTSL2	1.60e-03	8	227	2	C0018566
Disease	hydroxypalmitoyl sphingomyelin (d18:1/16:0(OH)) measurement	PCSK9 MUSK	1.60e-03	8	227	2	EFO_0800583
Disease	mean arterial pressure	TBC1D19 PCNX3 ESRRB SVEP1 AGXT PKHD1 STIM2 TFAP2D TFAP2B MTHFR LRBA	1.79e-03	499	227	11	EFO_0006340
Disease	uridine measurement	ESRRB LGALS13 CSMD1	1.89e-03	32	227	3	EFO_0010546
Disease	carboxypeptidase B measurement	CTRB2 CBFA2T3	2.05e-03	9	227	2	EFO_0801453
Disease	molar-incisor hypomineralization	TTLL12 KCNG1	2.05e-03	9	227	2	EFO_0005321
Disease	level of Sphingomyelin (d36:1) in blood serum	PCSK9 ANKRD17	2.05e-03	9	227	2	OBA_2045178
Disease	1-palmitoyl-2-arachidonoyl-GPI (16:0/20:4) measurement	MBOAT7 MUSK	2.05e-03	9	227	2	EFO_0800412
Disease	retinal degeneration (implicated_via_orthology)	PDE6C PROM2 EYS	2.07e-03	33	227	3	DOID:8466 (implicated_via_orthology)
Disease	Complement deficiency disease	CD55 C4A C4B	2.07e-03	33	227	3	C0272242
Disease	Lupus Erythematosus, Systemic	PCNX3 JAZF1 C4A C4B	2.21e-03	71	227	4	C0024141
Disease	Optic Atrophy	SLC25A46 MFN2	2.55e-03	10	227	2	C0029124
Disease	Nephroblastoma	NHS PCSK9	2.55e-03	10	227	2	Orphanet_654
Disease	Facies	DNMT3A ADAMTSL2	2.55e-03	10	227	2	C0282631
Disease	1-stearoyl-2-oleoyl-GPI (18:0/18:1) measurement	MBOAT7 MUSK	2.55e-03	10	227	2	EFO_0800469
Disease	Growth Disorders	ERCC6 DNMT3A ADAMTSL2	2.66e-03	36	227	3	C0018273
Disease	trypsin-2 measurement	CTRB2 CTRB1	3.10e-03	11	227	2	EFO_0008305
Disease	Barrett's esophagus (is_marker_for)	MKI67 MUC2	3.10e-03	11	227	2	DOID:9206 (is_marker_for)
Disease	Graves' disease (is_implicated_in)	C4A C4B MTHFR	3.35e-03	39	227	3	DOID:12361 (is_implicated_in)
Disease	Cleft upper lip	TFAP2A TFAP2B MTHFR	3.35e-03	39	227	3	C0008924
Disease	level of Phosphatidylinositol (18:0_20:3) in blood serum	MBOAT7 MUSK	3.70e-03	12	227	2	OBA_2045157
Disease	1-(1-enyl-palmitoyl)-2-palmitoyl-GPC (P-16:0/16:0) measurement	PCSK9 MUSK	3.70e-03	12	227	2	EFO_0800466
Disease	progression free survival, response to carboplatin, methylcobalamin deficiency type cblE, ovarian serous carcinoma	ADAMTS17 TTC7A EYS	4.13e-03	42	227	3	EFO_0004920, EFO_1001516, GO_0097328, MONDO_0009354
Disease	Autism Spectrum Disorders	PTCHD1 USH2A DNMT3A LRRN3	4.25e-03	85	227	4	C1510586
Disease	level of Sphingomyelin (d34:2) in blood serum	ANKRD17 MUSK	4.35e-03	13	227	2	OBA_2045174
Disease	Erythrocyte Mean Corpuscular Hemoglobin Test	ETFDH AGL	4.35e-03	13	227	2	C0369183
Disease	1-stearoyl-2-linoleoyl-GPI (18:0/18:2) measurement	MBOAT7 MUSK	4.35e-03	13	227	2	EFO_0800413
Disease	Finding of Mean Corpuscular Hemoglobin	ETFDH AGL	4.35e-03	13	227	2	C1261502
Disease	initial pursuit acceleration	ALCAM SPAG16 ARHGEF10L TTC7A	4.61e-03	87	227	4	EFO_0008434
Disease	bipolar I disorder	ANKHD1 DHH KCNG1 TFAP2B MUSK	4.78e-03	141	227	5	EFO_0009963
Disease	1-stearoyl-2-dihomo-linolenoyl-GPI (18:0/20:3n3 or 6) measurement	MBOAT7 MUSK	5.05e-03	14	227	2	EFO_0022085
Disease	diacylglycerol 38:4 measurement	MBOAT7 MUSK	5.05e-03	14	227	2	EFO_0020066
Disease	superior frontal gyrus grey matter volume measurement	TBC1D19 STIM2	5.05e-03	14	227	2	EFO_0006516
Disease	end stage renal disease (biomarker_via_orthology)	NAT1 SREBF2 LPIN1	5.68e-03	47	227	3	DOID:783 (biomarker_via_orthology)
Disease	phosphatidate measurement	MBOAT7 MUSK	5.79e-03	15	227	2	EFO_0020047
Disease	Disorder of eye	PDE6C MFN2 USH2A WDPCP EYS SLC45A2	6.14e-03	212	227	6	C0015397
Disease	sunburn	JAZF1 CBFA2T3 WDPCP SLC45A2	6.53e-03	96	227	4	EFO_0003958
Disease	1-stearoyl-2-arachidonoyl-GPI (18:0/20:4) measurement	MBOAT7 MUSK	6.59e-03	16	227	2	EFO_0800184
Disease	level of Sterol ester (27:1/18:1) in blood serum	PCSK9 ANKRD17	6.59e-03	16	227	2	OBA_2045195
Disease	Crohn Disease	DNMT3A MTHFR MUC2	6.75e-03	50	227	3	C0010346
Disease	hearing impairment	ERCC6 ESRRB HSD17B4 USH2A	7.01e-03	98	227	4	C1384666
Disease	alcoholic pancreatitis	CTRB2 JAZF1 AGMAT CTRB1	7.01e-03	98	227	4	EFO_1002013
Disease	free cholesterol to total lipids in small HDL percentage	ETFDH PCSK9 MUSK	7.13e-03	51	227	3	EFO_0022285
Disease	Craniofacial Abnormalities	B4GALT7 ERCC6 DNMT3A TFAP2A TFAP2B	7.28e-03	156	227	5	C0376634
Disease	Glycogen storage disease	PHKA1 AGL	7.43e-03	17	227	2	cv:C0017919
Disease	graft-versus-host disease (is_implicated_in)	MKI67 MTHFR	7.43e-03	17	227	2	DOID:0081267 (is_implicated_in)
Disease	Charcot-Marie-Tooth disease type 2	KIF1B MFN2	7.43e-03	17	227	2	cv:C0270914
Disease	alpha fetoprotein measurement	JAZF1 ABCB11 ANKRD17 INS-IGF2	7.52e-03	100	227	4	EFO_0010583

Protein segments in the cluster

Peptide	Gene	Start	Entry
AHGCVTAVSGKALPS	TACC1	171	O75410
LGLDHCHSFISGTAP	ACSBG2	386	Q5FVE4
QTPDGVHCLVGFTLT	NAT1	226	P18440
ALLGTTFGCGVPAIH	CTRB2	11	Q6GPI1
APASSVGGHLCGTLA	BRAT1	406	Q6PJG6
GHCGPVAFLAVATSI	ARHGEF10L	1111	Q9HCE6
FSVTLLGFCNSKPHD	ALG1	61	Q9BT22
APCGGHLTASSGVIL	CSMD1	756	Q96PZ7
KGHLLQGSTTRTCLP	CSMD3	3381	Q7Z407
AFCAGLLVSHPVLTQ	CDNF	11	Q49AH0
SVHVSPVEGLCLAGG	C4B	866	P0C0L5
SCGSLNVTLEHPLFV	DNMT3A	496	Q9Y6K1
NGFSLIGAHTDSPCL	DNPEP	96	Q9ULA0
SGLGSELEPSCLHSI	FAM220BP	171	B1ANY3
SGSVVLGCLFAPKLH	GRM2	801	Q14416
LSFLSPHDLCQLGST	FBXO4	71	Q9UKT5
LISHGFGSPAVCAAV	TFAP2A	381	P05549
SLCAFLHGIAQPGVL	ABCB11	66	O95342
SEHLCGINFTGSVPT	ALDH4A1	276	P30038
DLCGAVVLLTHGPAF	AMN	251	Q9BXJ7
QGSLASGVLPIKCSH	ARL17A	96	Q8IVW1
SPFHLAASKGLTECL	ANKRD35	56	Q8N283
HNGETPLFLAVSSCL	ASB14	116	A6NK59
VTFHPTISGLIASGC	AMBRA1	101	Q9C0C7
SFESPLTLAACGGHV	ANKRD17	466	O75179
SHTLCVTAQLPGAGG	DMC1	136	Q14565
SSISLPIGHLGCISL	DMRTC1;	176	Q5HYR2
ALSACHGLTGFFQLP	ADAMTS12	156	P58397
VLGHPGSLVSLSACG	ADAMTS17	131	Q8TE56
DGHNLPSLVCVITGS	ALG1L	41	Q6GMV1
ITHGFGAPAICAALT	TFAP2B	401	Q92481
LITHGFGTPAICAAL	TFAP2D	381	Q7Z6R9
FSLITHGFGGPAICA	TFAP2E	386	Q6VUC0
CLAHGPLGVLASQTA	IGDCC4	121	Q8TDY8
SLGGSHLRVSFCAPG	RAVER1	286	Q8IY67
PVHTFFGGPTCKLLT	RFWD3	686	Q6PCD5
VLRHPGSLASFSTCG	ADAMTS19	226	Q8TE59
LPSGIGHITNCFLSV	MFN1	101	Q8IWA4
VVTVASSGAGIHPLC	ERCC6	886	P0DP91
ILTGCVAFARHVGPT	RELCH	581	Q9P260
VEFPFLVLLISGGHC	OSGEPL1	161	Q9H4B0
CQELLASGLVPGLHF	MTHFR	306	P42898
ALPHTLLTASLSFCG	OR1A2	156	Q9Y585
VGLTVAIFHLPFCGS	OR10AC1	161	Q8NH08
THIVTEFILLGFPGC	OR11H4	16	Q8NGC9
GGTCHAIFLSSGIVS	EYS	2111	Q5T1H1
GSFHLDPANLKGCTS	LAMA3	1441	Q16787
PGHSVALCLAVAFKS	NCBP1	496	Q09161
LTTLPSDFCGLTHLV	LRRC59	51	Q96AG4
LHSLGQSSDAFPLCL	NAA80	91	Q93015
IHVFILGCFSAGLPK	IL15	31	P40933
CGRQHTLAFVPSSGL	HERC3	301	Q15034
LSTTEGSHAFLPCKA	HMCN2	4041	Q8NDA2
VVDHTAGLPCQGTFL	KIF1B	1271	O60333
KCHGLSVEGFVLPSS	PHKA1	1081	P46020
KLPAGRCSFSLHSGI	ERN2	666	Q76MJ5
VSGPGLSLCNDVIHT	HERC1	181	Q15751
SLHPLTFSCGDKLTL	IL12RB2	836	Q99665
FGGCGLHFPTLADLI	JAZF1	16	Q86VZ6
LSGGLPRKCSVFHLF	B4GALT7	21	Q9UBV7
GHTCFTLTGLLGTLV	CD55	361	P08174
GGLLVNFHPSILTCL	CAND1	166	Q86VP6
SLLLASGVFLGPHNS	FBXW5	151	Q969U6
RLSGLSLPSFCAVHL	PCNX3	1541	Q9H6A9
VFHSILAGLACGLGT	PCNX4	141	Q63HM2
TLTGCSALPGTSHVL	PCSK9	631	Q8NBP7
ALCLGIVAPHSSGLG	GGT7	171	Q9UJ14
GLSDTCIPLHASGRL	KSR1	246	Q8IVT5
GIALAGAHTVPASAC	OR51S1	91	Q8NGJ8
TCGSHIGVILAFSTP	OR52E6	241	Q96RD3
FALLGGHPCFLTTQD	OTC	101	P00480
EVVLSCPNGGSLTHT	MUC2	5131	Q02817
FSDFPLTEHGLIKCG	PDE6C	511	P51160
QLFCGLPSLHSESLV	FAM205A	431	Q6ZU69
QLFCGLPSLHSESLV	FAM205BP	161	Q63HN1
PGSLAETICLVTGTH	FAM234B	216	A2RU67
FQCISGIFVHTLSPG	IL16	376	Q14005
PSSHVLSGACAGAVA	SLC25A28	261	Q96A46
GVSAHLQPCKAGTTR	KLHL9	11	Q9P2J3
LVLSGSQEGPCLIHS	LRBA	2711	P50851
LPSIAISLCGGLSDH	LPIN1	461	Q14693
AVGLGLTLFTCGPHT	MBOAT7	36	Q96N66
ETHGFICQKGTDPSL	MRC2	1101	Q9UBG0
EPIGCDGVLFSTHTL	ADAMTSL2	186	Q86TH1
FIFHSSTHLGSGIPC	MMAA	26	Q8IVH4
HSGLPGKVFACLSVL	KCNG1	221	Q9UIX4
PDILGSSGAAVHTCV	RPS6KA5	701	O75582
ADFLFLSGHIICSPL	MRGPRX3	71	Q96LB0
FSTGHANSPCTIIIG	MKI67	706	P46013
CGGTLIHPSFVLTAA	PRTN3	56	P24158
GQIFCLHGGLSPSID	PPP2CB	161	P62714
GQIFCLHGGLSPSID	PPP2CA	161	P67775
RIGCHGSSLLILAPS	DDX31	621	Q9H8H2
HPVLESGLLASAGCS	CBFA2T3	26	O75081
LCAAPGGKTTHIAAL	NSUN6	241	Q8TEA1
ALEFSGSLFPHAICL	ITFG2	11	Q969R8
LCFTSDGLHLLTVGT	ERCC8	251	Q13216
VLPSGIGHTTNCFLR	MFN2	121	O95140
PHSALILDVACGTGL	METTL27	66	Q8N6F8
FHISLGTVGPNSGCS	MED14	831	O60244
GIFSQISHPGRLCLL	OR2T10	16	Q8NGZ9
HCLLESPTGSGKSLA	BRIP1	41	Q9BX63
LCAFQGTVSLHAPTG	GPR149	551	Q86SP6
GQALCSASLHVSGLP	OBSCN	5456	Q5VST9
GIIGSGLCVFSKHPI	SMPD2	76	O60906
VGSCVIIKGTPIHSF	LGALS13	16	Q9UHV8
SLISCHPSGAILLVG	WDPCP	381	O95876
AHTLSGACLDPGAFK	ETFDH	111	Q16134
LSCVGAAVALHPESF	HTT	716	P42858
FIGETLDLPCHSTGI	IGSF10	586	Q6WRI0
DALPGHVGTACLLSS	GPCPD1	246	Q9NPB8
FTLVGGHISPLLVAC	ILVBL	71	A1L0T0
FPNAGKSSLLSCVSH	GTPBP10	156	A4D1E9
VLGDCTHSPGSLQIS	BPIFA1	176	Q9NP55
LTVQTCGLTFIHPAG	C2orf83	81	Q53S99
LFGFLGPLVAVASCH	C5AR2	206	Q9P296
LGSFESVHLGSPCLL	CYP24A1	101	Q07973
AVGVFAPLTAHGTLL	DHH	321	O43323
GFLTGLATGTTLCQH	GAS2L1	51	Q99501
DGTIFHPHSGLCLSA	GALNT4	536	Q8N4A0
VLLGVLSVCAASGHG	FUT11	11	Q495W5
ASLAGFDKPILHGLC	HSD17B4	521	P51659
PVKDLLGCFHSGTES	ARFGEF3	1621	Q5TH69
LEAQACTGGIIHPTT	DSP	2651	P15924
FAVVITDGHVTGSPC	COL6A2	156	P12110
HRGSNTCGITKFPLT	CTSW	346	P56202
IVTGLPGCHASELCA	DNAAF9	751	Q5TEA3
ICGVLPLSVTHAGTT	BAHD1	451	Q8TBE0
HPTGFLGSLCTALFV	ADPRHL1	166	Q8NDY3
TCIQASAGGHPLELS	DENND4B	66	O75064
PVVCGVSSLGIDHTS	FPGS	216	Q05932
GICVSHSDPALGSVA	LAMB4	406	A4D0S4
DSGSPLVCNGLIHGI	ELANE	201	P08246
LVLHVPGCSVFLFGE	FTCDNL1	76	E5RQL4
FGACSGLKVTVPSHT	HEPACAM2	26	A8MVW5
RHLGSSCGSFIKTEP	ESRRB	6	O95718
SGSLHILSGPVFQKC	FDXACB1	366	Q9BRP7
GVSLTGTKHNPFICT	DNAJA3	66	Q96EY1
GSVSCPLHASRGVLS	POLI	556	Q9UNA4
SFLKLPISGTHCIVG	SLC20A1	121	Q8WUM9
PISGTHCIVGATIGF	SLC20A1	126	Q8WUM9
SFLRLPISGTHCIVG	SLC20A2	106	Q08357
PISGTHCIVGSTIGF	SLC20A2	111	Q08357
GRCVSAHPGLLQTLA	SBK3	91	P0C264
TLFPRGGVAACITHN	SACS	2846	Q9NZJ4
GFLLQPVVGSASDHC	SLC45A2	81	Q9UMX9
PSGLSKTIICHVEGF	ALCAM	426	Q13740
KSLCLSNGGIFPETH	MEST	171	Q5EB52
SLVGAAFGCGVPAIH	CTRB1	11	P17538
FCLGVSVAASSHVPI	CUL4B	101	Q13620
SVHVSPVEGLCLAGG	C4A	866	P0C0L4
LGTSDSPVLFIHCPG	INS-IGF2	111	F8WCM5
ILPSGGKISSALHFC	MMAB	171	Q96EY8
TLLCSSGHPGVKVIF	PIDD1	466	Q9HB75
SVLGLHTLLALCSPG	PRR14L	1816	Q5THK1
KAFSTCGPHLSVVSL	OR1E3	236	Q8WZA6
GYQKPLSTCGSHLIA	OR5B17	231	Q8NGF7
LEAVGCTGHPFLLSL	PKN3	611	Q6P5Z2
SKPFTGCIRHFVIDG	LAMA4	1786	Q16363
PAFASVHVLCGFIAG	PAOX	371	Q6QHF9
VASSGAGIHPLCLVS	PGBD3	421	Q8N328
ALPHTLLTASLSFCG	OR1A1	156	Q9P1Q5
CGSHIGVILAFFTPA	OR52E8	246	Q6IFG1
SKGLATCEGFIATLP	ALOX15B	581	O15296
GGCLHSLPITVTTAQ	USH2A	1226	O75445
VAGAALLVEGHSSCP	RAB11FIP1	821	Q6WKZ4
RNPLTLVISGSGHCA	AGXT	71	P21549
DPFVGTGGLLIACAH	TRMT11	221	Q7Z4G4
IGTIVEFTCDPGHSL	SEZ6L	586	Q9BYH1
SDCFPSQLLVHGALA	TCAF1	231	Q9Y4C2
LLSTISPGAFIGLHN	LRRN3	151	Q9H3W5
DTFGSPIHCISTAGV	NHS	601	Q6T4R5
GDPASCSVLGSLNLH	PLEKHG4	1101	Q58EX7
SFLEPCTQQGLGAHI	SPATA31A6	786	Q5VVP1
LGAPLHNSCISALFL	PTCHD1	696	Q96NR3
FVAPVTVLGVACGHL	GPR150	241	Q8NGU9
KILLPLSGSHLFTCG	SEMA4B	136	Q9NPR2
AGCIPLTLGGDHTIT	AGMAT	151	Q9BSE5
VCSPGGATIHALHFL	PYCR2	231	Q96C36
CVGTVLGESAAPATH	WDR17	991	Q8IZU2
SGPFTCVILSLGDHT	PKHD1	1426	P08F94
LLVQGGAAAPISSHC	IL22	26	Q9GZX6
LLFTSNQAPGGTHKC	IL9R	81	Q01113
CGSHLAFSSAPAQGL	PRSS8	306	Q16651
GLSITGSHILCGDFL	SGMS2	211	Q8NHU3
FKIGSLLGLLAPHSC	MROH2B	926	Q7Z745
CHPGFDLVGSSIILC	SVEP1	406	Q4LDE5
GHLPRFFGTAVTCLL	RRP12	411	Q5JTH9
SAAGGSHPDCVQLLL	ANKDD1A	231	Q495B1
KFCGATIAGLSLLSP	ALKBH7	126	Q9BT30
PLTLAACGGHVELAA	ANKHD1	441	Q8IWZ3
ALFCHLISPQAVGSG	CLCN1	176	P35523
SHFVSSAGEFKLPCL	TEPP	191	Q6URK8
GLSSFHIPSIGAACV	SPG11	1241	Q96JI7
LAHPSTLGLAVGVAC	PTRH2	11	Q9Y3E5
GHALPGSFFLIIGLC	TMEM45B	6	Q96B21
LSGSHNTLAPTCFKA	RSPH3	116	Q86UC2
NGHCLSKDSSPVGLV	PHETA2	171	Q6ICB4
CFGPAALGHLLVSTS	WDR90	891	Q96KV7
DGLVAVSHPCTGTTF	WDR90	1546	Q96KV7
KLGSHSVASCAPQLL	ZC3H3	246	Q8IXZ2
ATSHGLSVLLLVCGF	VSTM2A	216	Q8TAG5
AVSGGLRPFVSHTCT	TRPM6	711	Q9BX84
GPLCSLDSNLSHFIL	TRPM5	171	Q9NZQ8
THVGAGSLCQALLPG	SEC16A	416	O15027
GATDCKFLGPAEHLT	PROM2	26	Q8N271
GLASLFTENVLAHPC	SLC25A46	106	Q96AG3
CGFQIAHNSGLPSLT	STIM2	441	Q9P246
VLSGHEGPISGLCFN	PWP2	496	Q15269
STGCSGILISPQHVL	PRSS35	151	Q8N3Z0
LPKCNVLLTGFGHTD	SPAG16	381	Q8N0X2
LHITGKLPAGSACSD	SREBF2	676	Q12772
CLFPHLDTTGTVNGK	SFMBT2	511	Q5VUG0
LSPSLSSGEGHFVCL	ZNF775	96	Q96BV0
DHFFGLPGLLCTISL	ELAC1	66	Q9H777
HLVATGISCFLGSGL	SEMA5B	1036	Q9P283
GSEHFCPLSLIRVFG	SUCO	436	Q9UBS9
VFGSVRTHGIAVSPC	GTF3C4	471	Q9UKN8
VFSTLFLDQPGGCHV	TTLL12	626	Q14166
KCFRVSHTLAGDGVP	ZBTB47	681	Q9UFB7
SHPLIFSSLIGSGCQ	TM9SF3	286	Q9HD45
FSFGLGPTCHQLLQG	VWA5B2	476	Q8N398
GFCIQEAAGLFPTSH	TTC7A	731	Q9ULT0
PECGKAFSQSVHLTL	ZNF835	141	Q9Y2P0
TGAFQPTCALITVGH	SEMA3G	136	Q9NS98
VACHPSKALIASAGA	STRN4	731	Q9NRL3
GICSVSGFVHSLEGL	SLC32A1	501	Q9H598
FVLGPVGTTLHLHSC	TBCCD1	361	Q9NVR7
LCLLAAGHSEPGVSQ	TRBV17	11	A0A087X0K7
VTLAAHFLGLGAPNC	ZBED1	211	O96006
KGSFEALSCPHGRLT	TRANK1	1311	O15050
TAVHALLAPACLAGT	TMEM177	166	Q53S58
SHPSGIVSLCLLFET	TBC1D19	406	Q8N5T2
VSSVGNSALLCPHGG	USP48	766	Q86UV5
FCVHGGLSPSIQTLD	PPP4C	161	P60510
GHTGAVLCLVLDTPG	WDR86	191	Q86TI4
IGILDSSLHFGPVCF	WDR87	601	Q6ZQQ6
QGTAVHLAAPACLFS	MST1R	151	Q04912
HALAGEISPFLCSGS	TRRAP	2646	Q9Y4A5
TDFLKTSHVRGPCGV	ZBBX	741	A8MT70
CGKTFTVPSGFLEHV	ZNF560	381	Q96MR9
GFCASPIEESHGALI	ZNF283	46	Q8N7M2
QKGHILSGTSCVPLG	ZAN	1851	Q9Y493
CVSLAAGLPHFSSGI	AGL	1081	P35573
GSFVTLHCTATGIPV	MUSK	226	O15146
LLGCSLTADGLPLHF	MYORG	131	Q6NSJ0
LLACGSFNPITKGHI	NMNAT2	11	Q9BZQ4