Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcessdefense response to virus

USP20 ADARB1 LYST

4.97e-04342103GO:0051607
DomainZnf_C2H2-like

ZBTB40 RNF138 ZNF407

7.39e-03796103IPR015880
DomainZnf_C2H2

ZBTB40 RNF138 ZNF407

7.62e-03805103IPR007087
DomainZnF_C2H2

ZBTB40 RNF138 ZNF407

7.70e-03808103SM00355
DomainARM-type_fold

LYST NOC4L

1.34e-02339102IPR016024
Domain-

USP20 RNF138

2.28e-024491023.30.40.10
DomainZnf_RING/FYVE/PHD

USP20 RNF138

2.38e-02459102IPR013083
CoexpressionGSE11057_NAIVE_CD4_VS_PBMC_CD4_TCELL_UP

ZBTB40 USP20 ZNF407

4.90e-05198103M3108
ToppCelldroplet-Liver-nan-3m-Lymphocytic|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZBTB40 LYST ZNF407

5.60e-06164103bf0d3ad9016a0b8011a2385bb92f0a4f5edad1d6
ToppCelldroplet-Liver-nan-3m-Lymphocytic-NK_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZBTB40 LYST ZNF407

5.60e-06164103950f87d9dacee45c9004a9bf894543de38f72ee5
ToppCelldroplet-Liver-nan-3m-Lymphocytic-NK/T|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZBTB40 LYST ZNF407

5.60e-06164103c33910a6d87580902e9e7bd27afe6ea63b5eff8d
ToppCell3'-Child09-12-SmallIntestine-Hematopoietic-B_cells-STAT1+_Naive_B|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ZBTB40 NOC4L

5.01e-04152102dd728aa3ffdb2c415730a62678f69cf0e8af09df
ToppCellBAL-Mild-Lymphocyte-B-Plasmablast-Plasmablast-Plasmablast|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ADARB1 GPAT4

5.28e-041561025d9e1df70f2e9219f6b029be2e39297605d36726
ToppCelldroplet-Heart-nan-3m-Endothelial-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADARB1 ZNF407

5.35e-04157102d85a2f56ae313baa9738e81d2756ce1fe1ba50db
ToppCellControl-B_naive-12|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

USP20 ADARB1

5.35e-041571024803f601c1ba43260aa09172acc7964aac2c8ccf
ToppCellfacs-Lung-Endomucin-24m-Epithelial-type_II_pneumocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZBTB40 USP20

5.69e-041621027b2949eba2b4aea239d96ed82aafab13b07624eb
ToppCellfacs-Lung-Endomucin-24m-Epithelial-Alveolar_Epithelial_Type_2|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZBTB40 USP20

5.69e-04162102497ae9f86a5e7946d0fde932b35719a382a6b691
ToppCell343B-Lymphocytic-ILC|343B / Donor, Lineage, Cell class and subclass (all cells)

USP20 ADARB1

5.97e-04166102a54377c703efff42d2cc1a8fdb610facc58053dd
ToppCellfacs-Lung-18m-Hematologic-lymphocytic-CD4-positive,_alpha-beta_T_cell-CD4-positive,_alpha-beta_T_cell_l21|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

USP20 NOC4L

6.26e-04170102bda900c836e0f2c1d7b442beb50b672d025b2420
ToppCellMild/Remission-B_naive-8|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

ADARB1 LYST

6.48e-04173102694d02c4d2dc2de4b344544f9124fec40fcf7d8f
ToppCellSevere-B_naive-8|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)

ADARB1 LYST

6.56e-04174102f3f8c924420f46321bd47e2b97f18c7241541599
ToppCellCV-Severe-7|CV / Virus stimulation, Condition and Cluster

LYST ZNF407

6.71e-041761023de0c7d77210049e5616db21eed1490a17a5ec2d
ToppCellCV-Severe-7|Severe / Virus stimulation, Condition and Cluster

LYST ZNF407

6.78e-0417710282fdd6185b368f54f03de389427cbe3071d21a99
ToppCell(4)_B_cells-(4)_B_mantle|(4)_B_cells / Spleen cell shreds - cell class (v1) and cell subclass (v1)

ADARB1 LYST

7.25e-0418310221b7fb6482eb1d5d31a4029e47e0992e8ddc8e2c
ToppCelldroplet-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l44-58|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

USP20 ADARB1

7.25e-04183102dc9602bed3136db91faeffef177006246dc92743
ToppCell343B-Lymphocytic-ILC|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

USP20 ADARB1

7.73e-04189102c26428871dc3261327d89cacaba6e21e004ff1f3
ToppCellBLOOD--(2)_B_cell-(2)_Naive_B_cells|(2)_B_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

ADARB1 LYST

7.81e-04190102bde288cea27bbdc3ca05737a00fe30a0103a4c74
ToppCellCD8+_Memory_T_cell-CV-7|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster

ZBTB40 LYST

7.89e-041911029454f642c3621370fa23640b631301346b300950
ToppCellILEUM-inflamed-(2)_B_cell-(2)_Naive_B_cells|(2)_B_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

ADARB1 LYST

8.14e-04194102a89e67a40382600739be92e395bf47dd44aa4122
ToppCellMild/Remission-B_naive-8|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)

ADARB1 LYST

8.22e-041951020a3221e4d1fa31a35868bdda0f0cc873c233b407
ToppCellmLN-B_cell-Follicular_B_cell|B_cell / Region, Cell class and subclass

ADARB1 LYST

8.64e-042001028fbd27ffcfd0702ad3c340d32455e36a01617139
ToppCell10x_5'_v1-Non-neoplastic-Lymphoid-CD4/CD8-CD8_cytotoxic-Z|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

RNF138 LYST

8.64e-0420010248d79c7a9a2d3c10b41e152baf28fb00a4729e48
Drugdihydroflavonol

ADARB1 LYST

4.37e-0523102CID000147806
DrugTriamcinolone [124-94-7]; Up 200; 10.2uM; HL60; HG-U133A

ZBTB40 USP20 NOC4L

6.37e-051881031395_UP
DrugCyproheptadine hydrochloride [969-33-5]; Down 200; 12.4uM; MCF7; HT_HG-U133A

ZBTB40 USP20 LYST

7.10e-051951031521_DN
DrugTremorine dihydrochloride [300-68-5]; Down 200; 15uM; MCF7; HT_HG-U133A

ZBTB40 USP20 LYST

7.43e-051981033196_DN
DrugCefotiam hydrochloride; Up 200; 7.2uM; MCF7; HT_HG-U133A

ZBTB40 USP20 LYST

7.43e-051981035361_UP
DrugEthaverine hydrochloride [985-13-7]; Up 200; 9.2uM; MCF7; HT_HG-U133A

ZBTB40 USP20 LYST

7.54e-051991035337_UP
DrugLobeline alpha (-) hydrochoride [134-63-4]; Down 200; 10.6uM; MCF7; HT_HG-U133A

ZBTB40 USP20 LYST

7.54e-051991036258_DN
DrugTrimethadione [127-48-0]; Down 200; 28uM; PC3; HT_HG-U133A

USP20 ADARB1 ZNF407

7.66e-052001034086_DN
Drugalachlor

RNF138 ADARB1

1.41e-03130102ctd:C000188
DrugDigitoxigenin [143-62-4]; Up 200; 10.6uM; MCF7; HT_HG-U133A

ZBTB40 RNF138

2.32e-031671024801_UP
DrugDigoxin [20830-75-5]; Up 200; 5.2uM; PC3; HT_HG-U133A

ZBTB40 ZNF407

2.37e-031691026724_UP
DrugDigoxigenin [1672-46-4]; Up 200; 10.2uM; PC3; HT_HG-U133A

ZBTB40 ZNF407

2.40e-031701024680_UP
DrugTrichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A

ADARB1 LYST

2.48e-031731025625_UP
DrugLY 294002; Up 200; 10uM; MCF7; HT_HG-U133A_EA

ADARB1 LYST

2.51e-031741021019_UP
DrugTrichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A

USP20 LYST

2.60e-031771025745_UP
DrugTrichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A

ADARB1 LYST

2.60e-031771023993_UP
Drugtrichostatin A, Streptomyces sp.; Up 200; 1uM; MCF7; HT_HG-U133A

ADARB1 LYST

2.60e-031771025945_UP
Drugtrichostatin A, Streptomyces sp.; Up 200; 1uM; MCF7; HT_HG-U133A

ADARB1 LYST

2.74e-031821026879_UP
DrugCP-690334-01 [459212-38-5]; Up 200; 10uM; MCF7; HT_HG-U133A

ADARB1 LYST

2.86e-031861024380_UP
Drug17-AAG; Up 200; 1uM; MCF7; HT_HG-U133A

ZBTB40 ADARB1

2.89e-031871026978_UP
DrugEstradiol-17 beta [50-28-2]; Up 200; 14.6uM; HL60; HT_HG-U133A

ZBTB40 LYST

2.92e-031881021299_UP
DrugHycanthone [3105-97-3]; Down 200; 11.2uM; MCF7; HT_HG-U133A

ZBTB40 USP20

2.92e-031881025691_DN
DrugTetrandrine [518-34-3]; Up 200; 6.4uM; PC3; HT_HG-U133A

USP20 ZNF407

2.95e-031891025821_UP
DrugBenzbromarone [3562-84-3]; Up 200; 9.4uM; HL60; HT_HG-U133A

ZBTB40 LYST

2.95e-031891021291_UP
Drug17-DMAG; Down 200; 0.1uM; MCF7; HT_HG-U133A

ZBTB40 LYST

3.01e-031911025210_DN
Drugfluphenazine dihydrochloride; Down 200; 10uM; MCF7; HT_HG-U133A

ZBTB40 LYST

3.01e-031911025234_DN
DrugLY294002; Up 200; 10uM; PC3; HT_HG-U133A

LYST ZNF407

3.01e-031911025970_UP
Drugretinoic acid; Up 200; 1uM; MCF7; HG-U133A

USP20 ADARB1

3.01e-03191102224_UP
DrugDrofenine hydrochloride [548-66-3]; Up 200; 11.4uM; MCF7; HT_HG-U133A

ADARB1 LYST

3.01e-031911026776_UP
DrugDilazep dihydrochloride [20153-98-4]; Up 200; 6uM; PC3; HT_HG-U133A

ZBTB40 ADARB1

3.04e-031921027364_UP
DrugTrichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A

ADARB1 ZNF407

3.04e-031921023332_UP
Drugindomethacin, USP; Up 200; 100uM; PC3; HG-U133A

ZBTB40 USP20

3.04e-03192102452_UP
DrugBenfotiamine [22457-89-2]; Down 200; 8.6uM; HL60; HT_HG-U133A

USP20 ADARB1

3.08e-031931022177_DN
DrugGallamine triethiodide [65-29-2]; Down 200; 4.4uM; HL60; HG-U133A

USP20 LYST

3.08e-031931021375_DN
Diseasesmoking status measurement

IZUMO3 ADARB1 ZNF407

5.91e-031160103EFO_0006527
DiseaseC-reactive protein measurement

ZBTB40 USP20 ADARB1

6.59e-031206103EFO_0004458
Diseaseobsolete_red blood cell distribution width

IZUMO3 ZBTB40 ZNF407

8.95e-031347103EFO_0005192

Protein segments in the cluster

PeptideGeneStartEntry
RRKRKMHLVFEYCDH

CDKL4

71

Q5MAI5
RLCKHALYCRWMRVH

ADARB1

666

P78563
KHVHLMCYRICVRAL

GPAT4

211

Q86UL3
CTRKRHRRCEYSHFM

LYST

496

Q99698
RKYKVWMRHRYHSCC

NOC4L

86

Q9BVI4
HFCIFHRRKMKAIRR

IZUMO3

196

Q5VZ72
CRCCAKQIKFYRMRH

RNF138

86

Q8WVD3
ILCIHLKRFRHEVMY

USP20

581

Q9Y2K6
HVKRCHAREMKFYCR

ZNF407

546

Q9C0G0
VKRHLGMREYKCHVC

ZNF407

1586

Q9C0G0
HFYCRLKVHMKRCRV

ZBTB40

746

Q9NUA8