Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionphosphatidylinositol-3,5-bisphosphate 5-phosphatase activity

OCRL FIG4

3.75e-0461012GO:0043813
GeneOntologyMolecularFunctionprolactin receptor binding

CSH1 CSH2

5.23e-0471012GO:0005148
GeneOntologyMolecularFunctionphosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity

OCRL FIG4

5.23e-0471012GO:0034485
GeneOntologyMolecularFunctionG protein-coupled peptide receptor activity

MCHR1 NMUR2 LGR5 BDKRB2 TACR3

5.77e-041331015GO:0008528
GeneOntologyMolecularFunctionpeptide receptor activity

MCHR1 NMUR2 LGR5 BDKRB2 TACR3

7.28e-041401015GO:0001653
GeneOntologyMolecularFunctionneuropeptide binding

MCHR1 NMUR2 SORL1

8.61e-04371013GO:0042923
GeneOntologyMolecularFunction7SK snRNA binding

CCNT1 CCNT2

8.91e-0491012GO:0097322
GeneOntologyMolecularFunctioncyclic nucleotide binding

PDE4D STING1 CNGA4

1.01e-03391013GO:0030551
GeneOntologyMolecularFunctionphosphatidylinositol-4,5-bisphosphate 5-phosphatase activity

OCRL FIG4

1.11e-03101012GO:0004439
GeneOntologyMolecularFunctiongrowth hormone receptor binding

CSH1 CSH2

1.11e-03101012GO:0005131
GeneOntologyMolecularFunctionbeta-2 adrenergic receptor binding

PDE4D BDKRB2

1.11e-03101012GO:0031698
GeneOntologyMolecularFunctionphosphatidylinositol phosphate 4-phosphatase activity

OCRL FIG4

1.11e-03101012GO:0034596
GeneOntologyMolecularFunctionphosphatidylinositol trisphosphate phosphatase activity

OCRL FIG4

1.35e-03111012GO:0034594
GeneOntologyMolecularFunctionRoundabout binding

LRTM2 SLIT3

1.62e-03121012GO:0048495
GeneOntologyMolecularFunctionphosphatidylinositol-4,5-bisphosphate phosphatase activity

OCRL FIG4

1.62e-03121012GO:0106019
GeneOntologyMolecularFunctionL-arginine transmembrane transporter activity

SLC38A9 SLC38A4

1.91e-03131012GO:0061459
GeneOntologyMolecularFunctionphosphatidylinositol phosphate 5-phosphatase activity

OCRL FIG4

1.91e-03131012GO:0034595
DomainTIG

PLXNA3 EBF2 CAMTA1 NFAT5

2.18e-05311004PF01833
DomainIPT

PLXNA3 EBF2 CAMTA1 NFAT5

2.48e-05321004IPR002909
DomainFactor_5/8

F5 F8

2.84e-0521002IPR024715
DomainLRR_1

RANGAP1 CNTRL LRTM2 LGR5 LRFN2 SLIT3 SLITRK5

1.76e-042191007PF00560
DomainLRRNT

LRTM2 LGR5 LRFN2 SLIT3 SLITRK5

1.82e-04981005IPR000372
DomainLRRNT

LRTM2 LGR5 LRFN2 SLIT3 SLITRK5

1.82e-04981005SM00013
DomainLRRNT

LRTM2 LGR5 SLIT3 SLITRK5

1.85e-04531004PF01462
DomainCu_oxidase_CS

F5 F8

2.81e-0451002IPR033138
DomainCu-oxidase_3

F5 F8

2.81e-0451002IPR011707
DomainMULTICOPPER_OXIDASE1

F5 F8

2.81e-0451002PS00079
DomainCu-oxidase_3

F5 F8

2.81e-0451002PF07732
DomainLeu-rich_rpt_typical-subtyp

CNTRL LRTM2 LGR5 LRFN2 SLIT3 SLITRK5

3.80e-041771006IPR003591
DomainLRR_TYP

CNTRL LRTM2 LGR5 LRFN2 SLIT3 SLITRK5

3.80e-041771006SM00369
DomainIPT

PLXNA3 EBF2 NFAT5

3.97e-04271003SM00429
DomainSOMATOTROPIN_2

CSH1 CSH2

4.20e-0461002PS00338
DomainHormone_1

CSH1 CSH2

4.20e-0461002PF00103
DomainSOMATOTROPIN_1

CSH1 CSH2

4.20e-0461002PS00266
DomainCu_oxidase_Cu_BS

F5 F8

4.20e-0461002IPR002355
DomainSomatotropin

CSH1 CSH2

5.86e-0471002IPR001400
DomainPlakophilin/d_Catenin

PKP4 CTNND1

5.86e-0471002IPR028435
DomainLeu-rich_rpt

RANGAP1 CNTRL LRTM2 LGR5 LRFN2 SLIT3 SLITRK5

6.36e-042711007IPR001611
DomainLRR

CNTRL LRTM2 LGR5 LRFN2 SLIT3 SLITRK5

7.43e-042011006PS51450
DomainCyclin_L/T

CCNT1 CCNT2

7.78e-0481002IPR015429
DomainDUF4939

RTL8B RTL8A

1.24e-03101002PF16297
DomainDUF4939

RTL8B RTL8A

1.24e-03101002IPR032549
DomainCys-rich_flank_reg_C

LRTM2 LRFN2 SLIT3 SLITRK5

1.39e-03901004IPR000483
DomainLRRCT

LRTM2 LRFN2 SLIT3 SLITRK5

1.39e-03901004SM00082
DomainLDOC1-rel

RTL8B RTL8A

1.51e-03111002IPR032567
Domain-

RANGAP1 CNTRL LRTM2 LGR5 LRFN2 SLIT3 SLITRK5

1.70e-0332110073.80.10.10
DomainL_dom-like

RANGAP1 CNTRL LRTM2 LGR5 LRFN2 SLIT3 SLITRK5

1.92e-033281007IPR032675
DomainLRR_8

LRTM2 LGR5 LRFN2 SLIT3 SLITRK5

2.27e-031711005PF13855
DomainIg_E-set

PLXNA3 EBF2 CAMTA1 NFAT5

2.36e-031041004IPR014756
Domain-

F5 F8

2.48e-031410022.60.40.420
DomainAa_trans

SLC38A9 SLC38A4

3.66e-03171002PF01490
DomainAA_transpt_TM

SLC38A9 SLC38A4

3.66e-03171002IPR013057
DomainFA58C

F5 F8

5.58e-03211002SM00231
DomainFA58C_3

F5 F8

5.58e-03211002PS50022
DomainFA58C_1

F5 F8

5.58e-03211002PS01285
Pubmed

Balance between activating NKG2D, DNAM-1, NKp44 and NKp46 and inhibitory CD94/NKG2A receptors determine natural killer degranulation towards rheumatoid arthritis synovial fibroblasts.

KLRK1 CD226 KLRD1

4.72e-076101324673109
Pubmed

Desmopressin acetate as a haemostatic elevator in individuals with combined deficiency of factors V and VIII: a clinical trial.

F5 F8

8.35e-062101226599105
Pubmed

The molecular basis of factor V and VIII procofactor activation.

F5 F8

8.35e-062101219765210
Pubmed

An immunocompromised murine model of chronic Bartonella infection.

LYST PRKDC

8.35e-062101220395436
Pubmed

NK cells recognize and lyse Ewing sarcoma cells through NKG2D and DNAM-1 receptor dependent pathways.

KLRK1 CD226

8.35e-062101218657862
Pubmed

Factor VIII/V C-domain swaps reveal discrete C-domain roles in factor VIII function and intracellular trafficking.

F5 F8

8.35e-062101228057741
Pubmed

Nonspecific immune responses and mechanisms of resistance to Eimeria papillata infections in mice.

LYST PRKDC

8.35e-06210129234770
Pubmed

Identification of the interchain disulfide bonds of dimeric human placental lactogen.

CSH1 CSH2

8.35e-0621012438159
Pubmed

Therapeutic targeting of CC ligand 21 or CC chemokine receptor 7 abrogates pulmonary fibrosis induced by the adoptive transfer of human pulmonary fibroblasts to immunodeficient mice.

LYST PRKDC

8.35e-062101217392156
Pubmed

The factor VIII D1241E polymorphism is associated with decreased factor VIII activity and not with activated protein C resistance levels.

F5 F8

8.35e-062101215735794
Pubmed

Signs and lesions of experimental Sendai virus infection in two genetically distinct strains of SCID/beige mice.

LYST PRKDC

8.35e-06210128140728
Pubmed

Increased factor VIII coagulant activity levels in male carriers of the factor V R2 polymorphism.

F5 F8

8.35e-062101217287628
Pubmed

Spontaneous and experimental infections in scid and scid/beige mice.

LYST PRKDC

8.35e-06210128320959
Pubmed

Amino acid sequence of human chorionic somatomammotropin.

CSH1 CSH2

8.35e-06210124712450
Pubmed

Activated protein C has a regulatory role in factor VIII function.

F5 F8

8.35e-062101233512448
Pubmed

Boosting Natural Killer Cell-Mediated Targeting of Sarcoma Through DNAM-1 and NKG2D.

KLRK1 CD226

8.35e-062101232082316
Pubmed

Two structurally different genes produce the same secreted human placental lactogen hormone.

CSH1 CSH2

8.35e-06210126300056
Pubmed

ALK mutants in the kinase domain exhibit altered kinase activity and differential sensitivity to small molecule ALK inhibitors.

LYST PRKDC

8.35e-062101219249873
Pubmed

YIPF5 Is Essential for Innate Immunity to DNA Virus and Facilitates COPII-Dependent STING Trafficking.

STING1 YIPF5

8.35e-062101231391232
Pubmed

Studies of virus-induced myocardial injury in mice: value of the scid mutation on different genetic backgrounds and combined with other mutations.

LYST PRKDC

8.35e-06210128391609
Pubmed

Murine granulated metrial gland cell population in beige (bg/bg) and SCID (scid/scid) genotypes.

LYST PRKDC

8.35e-06210128075241
Pubmed

Beyond regulation of cell adhesion: local control of RhoA at the cleavage furrow by the p0071 catenin.

PKP4 CTNND1

8.35e-062101217264675
Pubmed

Factor XIII Val34Leu and the risk of venous thromboembolism in factor V Leiden carriers.

F5 F8

8.35e-062101211091190
Pubmed

Cotranslational sequestration of egg white proteins and placental lactogen inside membrane vesicles.

CSH1 CSH2

8.35e-06210126930851
Pubmed

SCID-bg mice as xenograft recipients.

LYST PRKDC

8.35e-06210129175014
Pubmed

Role of NKG2D, DNAM-1 and natural cytotoxicity receptors in cytotoxicity toward rhabdomyosarcoma cell lines mediated by resting and IL-15-activated human natural killer cells.

KLRK1 CD226

8.35e-062101225854581
Pubmed

Comparison of susceptibility of inbred and outbred infant mice to Escherichia coli heat-stable enterotoxin STa.

LYST PRKDC

8.35e-06210121639480
Pubmed

Epigenetic regulation of intestinal stem cells by Tet1-mediated DNA hydroxymethylation.

LGR5 TET1

8.35e-062101227856615
Pubmed

Translocation of bacteria from the gastrointestinal tract in immunodeficient mice.

LYST PRKDC

8.35e-06210128709573
Pubmed

Analysis of a major human chorionic somatomammotropin gene. Evidence for two functional promoter elements.

CSH1 CSH2

8.35e-06210126208192
Pubmed

Protective immunity to HIV-1 in SCID/beige mice reconstituted with peripheral blood lymphocytes of exposed but uninfected individuals.

LYST PRKDC

8.35e-06210128962121
Pubmed

Multiple origins of transcription for the human placental lactogen genes.

CSH1 CSH2

8.35e-06210126209277
Pubmed

Humanized mouse model of skin inflammation is characterized by disturbed keratinocyte differentiation and influx of IL-17A producing T cells.

LYST PRKDC

8.35e-062101223094018
Pubmed

NKG2D and CD94 bind to heparin and sulfate-containing polysaccharides.

KLRK1 KLRD1

8.35e-062101219555665
Pubmed

Branhamella catarrhalis pathogenesis in SCID and SCID/beige mice. Brief report.

LYST PRKDC

8.35e-06210128267959
Pubmed

Role of human natural killer cells during Epstein-Barr virus infection.

KLRK1 CD226

8.35e-062101225597312
Pubmed

Conservative mutations in the C2 domains of factor VIII and factor V alter phospholipid binding and cofactor activity.

F5 F8

8.35e-062101222613792
Pubmed

NKG2D and CD94 bind to multimeric alpha2,3-linked N-acetylneuraminic acid.

KLRK1 KLRD1

8.35e-062101219303396
Pubmed

The beneficial effect of blocking Kv1.3 in the psoriasiform SCID mouse model.

LYST PRKDC

8.35e-062101220739949
Pubmed

Infection of the laboratory mouse with the intracellular pathogen Ehrlichia chaffeensis.

LYST PRKDC

8.35e-06210129673277
Pubmed

Amino-acid sequence of human placental lactogen.

CSH1 CSH2

8.35e-06210125286363
Pubmed

Homozygous scid/scid;beige/beige mice have low levels of spontaneous or neonatal T cell-induced B cell generation.

LYST PRKDC

8.35e-06210128418200
Pubmed

Mycobacterium avium subspecies paratuberculosis triggers intestinal pathophysiologic changes in beige/scid mice.

LYST PRKDC

8.35e-062101211924817
Pubmed

Differential expression of ligands for NKG2D and DNAM-1 receptors by epithelial ovarian cancer-derived exosomes and its influence on NK cell cytotoxicity.

KLRK1 CD226

8.35e-062101226563374
Pubmed

Construction and analysis of recombinant DNA for human chorionic somatomammotropin.

CSH1 CSH2

8.35e-0621012593368
Pubmed

Evaluation of three lines of immunodeficient mice for the study of spontaneous metastatic tumors.

LYST PRKDC

8.35e-062101210225324
Pubmed

Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

MORC2 SLITRK5 ADGRF5 CAMTA1 NFAT5

1.13e-05100101510048485
Pubmed

Mice deficient in LMAN1 exhibit FV and FVIII deficiencies and liver accumulation of α1-antitrypsin.

F5 F8 GOLGB1

1.57e-0517101321795745
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

CNTRL APOB OCRL CRB1 RIF1 OSBPL2 SLITRK5 PRKDC HCFC2 CTNND1 GOLGB1

1.65e-057771011135844135
Pubmed

Regulation of P-TEFb elongation complex activity by CDK9 acetylation.

CCNT1 CCNT2

2.50e-053101217452463
Pubmed

POLQ inhibition elicits an immune response in homologous recombination-deficient pancreatic adenocarcinoma via cGAS/STING signaling.

STING1 PRKDC

2.50e-053101236976649
Pubmed

Differential placental expression profile of human Growth Hormone/Chorionic Somatomammotropin genes in pregnancies with pre-eclampsia and gestational diabetes mellitus.

CSH1 CSH2

2.50e-053101222387044
Pubmed

A CRISPR knockout screen identifies SETDB1-target retroelement silencing factors in embryonic stem cells.

MORC2 RESF1

2.50e-053101229728365
Pubmed

A low-copy repeat in Xq26 represents a novel putatively prenylated protein gene (CXX1) and its pseudogenes (DXS9914, DXS9915, and DXS9916).

RTL8B RTL8A

2.50e-05310129403077
Pubmed

Role of the human and murine cyclin T proteins in regulating HIV-1 tat-activation.

CCNT1 CCNT2

2.50e-053101210329126
Pubmed

Identification of multiple cyclin subunits of human P-TEFb.

CCNT1 CCNT2

2.50e-05310129499409
Pubmed

Factor V Leiden improves in vivo hemostasis in murine hemophilia models.

F5 F8

2.50e-053101216359510
Pubmed

Pulmonary alveolar proteinosis. A spontaneous and inducible disease in immunodeficient germ-free mice.

LYST PRKDC

2.50e-05310127717446
Pubmed

Coagulation procofactor activation by factor XIa.

F5 F8

2.50e-053101220456758
Pubmed

The requirement for DNAM-1, NKG2D, and NKp46 in the natural killer cell-mediated killing of myeloma cells.

KLRK1 CD226

2.50e-053101217875681
Pubmed

Recently reported familial hypercholesterolemia-related mutations from cases in the Middle East and North Africa region.

APOB SORL1

2.50e-053101230694837
Pubmed

Factor V Leiden mutation and high FVIII are associated with an increased risk of VTE in women with breast cancer during adjuvant tamoxifen - results from a prospective, single center, case control study.

F5 F8

2.50e-053101225592075
Pubmed

Stepwise phosphorylation of p65 promotes NF-κB activation and NK cell responses during target cell recognition.

KLRK1 CD226

2.50e-053101227221592
Pubmed

Cloning of a mouse homolog of CD94 extends the family of C-type lectins on murine natural killer cells.

KLRK1 KLRD1

2.50e-05310129464811
Pubmed

Analysis of the effect of natural sequence variation in Tat and in cyclin T on the formation and RNA binding properties of Tat-cyclin T complexes.

CCNT1 CCNT2

2.50e-053101210364329
Pubmed

Trastuzumab/pertuzumab combination therapy stimulates antitumor responses through complement-dependent cytotoxicity and phagocytosis.

LYST PRKDC

2.50e-053101235167491
Pubmed

XLP1 inhibitory effect by 2B4 does not affect DNAM-1 and NKG2D activating pathways in NK cells.

KLRK1 CD226

2.50e-053101224496997
Pubmed

Concomitant deletion of SLAM-family receptors, NKG2D and DNAM-1 reveals gene redundancy of NK cell activating receptors in NK cell development and education.

KLRK1 CD226

2.50e-053101231729776
Pubmed

Reversible immortalisation enables genetic correction of human muscle progenitors and engineering of next-generation human artificial chromosomes for Duchenne muscular dystrophy.

LYST PRKDC

2.50e-053101229242210
Pubmed

The Cockayne syndrome B protein, involved in transcription-coupled DNA repair, resides in an RNA polymerase II-containing complex.

CSH1 CSH2

2.50e-05310129312053
Pubmed

NKG2D engagement on human NK cells leads to DNAM-1 hypo-responsiveness through different converging mechanisms.

KLRK1 CD226

2.50e-053101236440686
Pubmed

Interpretation of correlations between coagulation factors FV, FVIII and vWF in normal and type 2 diabetes mellitus patients.

F5 F8

2.50e-053101222032085
Pubmed

Co-segregation of thrombophilic disorders in factor V Leiden carriers; the contributions of factor VIII, factor XI, thrombin activatable fibrinolysis inhibitor and lipoprotein(a) to the absolute risk of venous thromboembolism.

F5 F8

2.50e-053101212368162
Pubmed

Nkx2-2 expressing taste cells in endoderm-derived taste papillae are committed to the type III lineage.

LGR5 NKX2-2

2.50e-053101234097879
Pubmed

CD4 positive T helper cells contribute to retinal ganglion cell death in mouse model of ischemia reperfusion injury.

LYST PRKDC

2.50e-053101223792169
Pubmed

Cyclin T2 is essential for mouse embryogenesis.

CCNT1 CCNT2

2.50e-053101219364821
Pubmed

The human growth hormone gene locus: structure, evolution, and allelic variations.

CSH1 CSH2

2.50e-05310123030680
Pubmed

Thrombomodulin-dependent effect of factor VLeiden mutation on factor XIII activation.

F5 F8

2.50e-053101221774968
Pubmed

Interactions between Tat and TAR and human immunodeficiency virus replication are facilitated by human cyclin T1 but not cyclins T2a or T2b.

CCNT1 CCNT2

2.50e-053101210049833
Pubmed

TOX3 is a neuronal survival factor that induces transcription depending on the presence of CITED1 or phosphorylated CREB in the transcriptionally active complex.

CITED1 TOX3

2.50e-053101221172805
Pubmed

EWS/FLI mediates transcriptional repression via NKX2.2 during oncogenic transformation in Ewing's sarcoma.

EWSR1 NKX2-2

2.50e-053101218414662
Pubmed

Interactions of the scid or beige mutations with the viable motheaten mutation.

LYST PRKDC

2.50e-05310128781712
Pubmed

Isolation of Crb1, a mouse homologue of Drosophila crumbs, and analysis of its expression pattern in eye and brain.

CRB1 NKX2-2

2.50e-053101211744384
Pubmed

Late life metabolic syndrome, early growth, and common polymorphism in the growth hormone and placental lactogen gene cluster.

CSH1 CSH2

2.50e-053101215531513
Pubmed

Splicing variants of the human growth hormone mRNA: detection in pituitary, mononuclear cells and dermal fibroblasts.

CSH1 CSH2

2.50e-05310128674830
Pubmed

Nutlin-3a Enhances Natural Killer Cell-Mediated Killing of Neuroblastoma by Restoring p53-Dependent Expression of Ligands for NKG2D and DNAM-1 Receptors.

KLRK1 CD226

2.50e-053101233303573
Pubmed

Role of natural killer cells on engraftment of human lymphoid cells and on metastasis of human T-lymphoblastoid leukemia cells in C57BL/6J-scid mice and in C57BL/6J-scid bg mice.

LYST PRKDC

2.50e-05310128806787
Pubmed

Defective killing of Candida albicans hyphae by neutrophils from beige mice.

LYST PRKDC

2.50e-05310127769315
Pubmed

The CDK9-associated cyclins T1 and T2 exert opposite effects on HIV-1 Tat activity.

CCNT1 CCNT2

2.50e-053101210465067
Pubmed

The imprinted Zdbf2 gene finely tunes control of feeding and growth in neonates.

ZDBF2 CSH1 CSH2

2.61e-0520101335049495
Pubmed

Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette.

SLC38A4 PKP4 NIPAL3 CCNT1 RIF1 VPS13D TET1 CTNND1 CAMTA1

2.73e-05536101915840001
Pubmed

Exchangeable gene trap using the Cre/mutated lox system.

SLC38A4 PKP4 NIPAL3 CCNT1 RIF1 VPS13D TET1 CTNND1 CAMTA1

2.81e-05538101910512203
Pubmed

Reciprocal interactions of Pit1 and GATA2 mediate signaling gradient-induced determination of pituitary cell types.

CSH1 CSH2 FOXC1

3.04e-0521101310367888
Pubmed

Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways.

CCP110 PDE4D CNTRL FYCO1 VPS13D KCNMA1 NKX2-2 PRKDC GOLGB1

4.05e-05564101921565611
Pubmed

Chromosomal localization of homeobox genes and associated markers on porcine chromosomes 3, 5, 12, 15, 16 and 18: comparative mapping study with human and mouse.

APOB CSH1 CSH2

4.60e-052410138833235
Pubmed

Dendritic cells directly trigger NK cell functions: cross-talk relevant in innate anti-tumor immune responses in vivo.

LYST PRKDC

4.99e-054101210202929
Pubmed

Assessment of Cmv1 candidates by genetic mapping and in vivo antibody depletion of NK cell subsets.

KLRK1 KLRD1

4.99e-054101210464175
Pubmed

Type I interferon-driven susceptibility to Mycobacterium tuberculosis is mediated by IL-1Ra.

CH25H STING1

4.99e-054101231611644
Pubmed

EF-hand domains of MCFD2 mediate interactions with both LMAN1 and coagulation factor V or VIII.

F5 F8

4.99e-054101220007547
Pubmed

Developmental control and alternative splicing of the placentally expressed transcripts from the human growth hormone gene cluster.

CSH1 CSH2

4.99e-05410121378436
GeneFamilyCyclins|P-TEFb complex

CCNT1 CCNT2

8.32e-0546821281
GeneFamilyGrowth hormone family

CSH1 CSH2

2.07e-0466821175
GeneFamilyHyalectan proteoglycans|V-set domain containing|Sushi domain containing|C-type lectin domain containing

FREM1 KLRK1 KLRD1

4.90e-04416831298
GeneFamilyCD molecules|C-type lectin domain family|Killer cell lectin like receptors

KLRK1 KLRD1

8.98e-0412682621
GeneFamilyCyclins

CCNT1 CCNT2

4.95e-0328682473
GeneFamilyZinc fingers FYVE-type|Pleckstrin homology domain containing|Rho guanine nucleotide exchange factors

FYCO1 ZFYVE9

6.04e-033168281
GeneFamilyPhosphoinositide phosphatases

OCRL FIG4

6.43e-03326821079
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

PKP4 CTNND1

1.14e-0243682409
CoexpressionAtlasDevelopingGonad_e16.5_ovary_emap-9563_k-means-cluster#4_top-relative-expression-ranked_500

GGNBP2 ZNF148 RIF1 RESF1 NFAT5

2.17e-0572995gudmap_developingGonad_e16.5_ovary_500_k4
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle F_emap-6706_k-means-cluster#3_top-relative-expression-ranked_500

TBX15 PDE4D ZNF148 ADAM23 RIF1 TOX3 HCFC2 CAMTA1

2.18e-05249998gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle F_500_k3
CoexpressionAtlasDevelopingGonad_e12.5_epididymis_emap-29139_top-relative-expression-ranked_1000

RANGAP1 GGNBP2 ZNF148 PKP4 TTC14 EWSR1 OCRL LGR5 GDF3 RIF1 RESF1 TET1 TACR3 TDRD12

2.19e-058069914gudmap_developingGonad_e12.5_epididymis_1000
CoexpressionAtlaskidney_adult_CortVasc_Tie2_k-means-cluster#2_top-relative-expression-ranked_1000

CH25H IFI44 LGR5 F8 VPS13D ADGRF5 RTL8A NFAT5

8.52e-05302998gudmap_kidney_adult_CortVasc_Tie2_k2_1000
CoexpressionAtlasratio_induced-DefinitiveEndoderm_vs_StemCell_top-relative-expression-ranked_100

LGR5 BDKRB2 FREM1 CNGA4 FOXC1

1.01e-0499995PCBC_ratio_DE_vs_SC_100
ToppCellControl-T_cells|Control / group, cell type (main and fine annotations)

KLRK1 RESF1 CD226 PCNX1 KLRD1 SORL1

4.34e-061871016f4e8e0eba58da89b56587667555a5d4754e108c7
ToppCell-Unknown-Endothelial-Myofibroblast| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ZDBF2 ZFYVE9 ERCC6L2 KCNMA1 CARS2 KIF13A

4.48e-0618810166468fa95ad0395395301115286f2d8c0df5d3882
ToppCell-Unknown-Endothelial| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ZDBF2 ZFYVE9 ERCC6L2 KCNMA1 CARS2 KIF13A

4.48e-0618810167a81ac5c79c3eb26639b52d2b9fd5e7ef9798fd6
ToppCell-Unknown| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ZDBF2 ZFYVE9 ERCC6L2 KCNMA1 CARS2 KIF13A

4.48e-0618810169cb718bfe1358c6fd842f096e228eb0abb9aefc6
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PDE4D FREM1 EBF2 TOX3 ADGRF5 NFAT5

5.06e-061921016f7e7491426bbd6ed29a465b58bf67acb93dbb90a
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c04-COTL1|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

PDE4D WNK1 LYST KLRK1 CD226 KLRD1

5.21e-061931016778fcf8448e81fe18972d97ea8a30ab036d16fe5
ToppCellCOPD-Lymphoid-T|Lymphoid / Disease state, Lineage and Cell class

ADAM23 CH25H FYCO1 STING1 CD226 PCNX1

5.69e-061961016c9bdd505c3ab380ed7b272aa518df31a0a706a06
ToppCellmild-low-quality_cells|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

PLXNA3 TTC14 KLRK1 CCNT1 CD226 KLRD1

5.86e-061971016e4331969bd911d1ebb5453f40a7057297b5389b4
ToppCell10x_3'_v3-lymph_node_(10x_3'_v3)-lymphocytic-T_lymphocytic-type_I_NK_T_cell|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ADAM23 STING1 RESF1 CD226 PCNX1 KLRD1

5.86e-06197101651340570667914bffec741c72a8d09cc46abb8e8
ToppCell10x5'-lymph-node_spleen-Lymphocytic_T_CD4-Tfh|lymph-node_spleen / Manually curated celltypes from each tissue

ADAM23 CH25H STING1 RESF1 CD226 PCNX1

6.03e-061981016fbdd37ca3d4b61f266bf6146662cb300ef67b850
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Transitional_Principal-Intercalated_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PDE4D ADAM23 APOB FREM1 ADGRF5

2.07e-051461015e887e9de895fd453faa703997ef372cc6410fc49
ToppCell3'_v3-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

TTC14 KLRK1 SLITRK5 PCNX1 GOLGB1

2.14e-05147101594998bc40f5c08295cfe3bdcbe43f13b1e564b3d
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Connecting_Tubule_Intercalated_Cell_Type_A|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PDE4D FREM1 EBF2 TOX3 ADGRF5

2.36e-05150101587968ce885a4959616f0321f58517fe8029ba1b1
ToppCelldroplet-Liver-Hepatocytes-24m-Epithelial-Hepatocyte_(Pericentral_and_Periportal)|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC38A4 APOB F5 NNMT SERPINA7

2.68e-051541015a5289000597068ee8d559f89bce7bce31f35dd57
ToppCelldroplet-Liver-nan-3m-Lymphocytic-NK_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NIPAL3 LYST KLRK1 CD226 KLRD1

3.62e-051641015950f87d9dacee45c9004a9bf894543de38f72ee5
ToppCelldroplet-Liver-nan-3m-Lymphocytic-NK/T|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NIPAL3 LYST KLRK1 CD226 KLRD1

3.62e-051641015c33910a6d87580902e9e7bd27afe6ea63b5eff8d
ToppCelldroplet-Liver-nan-3m-Lymphocytic|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NIPAL3 LYST KLRK1 CD226 KLRD1

3.62e-051641015bf0d3ad9016a0b8011a2385bb92f0a4f5edad1d6
ToppCelldroplet-Marrow-nan-3m-Lymphocytic-immature_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

F5 LYST F8 VPS13D SORL1

3.62e-051641015f9a2cc12179d5621c9174ec01d7418a71edd28d1
ToppCellfacs-Limb_Muscle-forelimb_and_hindlimb-18m-Lymphocytic-T_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FYCO1 LGR5 KLRK1 KLRD1 SORL1

4.06e-051681015182f08106ac65ea501e2fb9139d3b44b7c4662c9
ToppCelldroplet-Lung-30m-Hematologic-myeloid-myeloid_dendritic_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ADAM23 ZDBF2 KLRK1 RTL8B KLRD1

4.17e-051691015b2d53159e344fad6fcdc485d5b8f6cf1bf094b1f
ToppCellfacs-Marrow-KLS-18m-Myeloid-promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAM23 CYP27A1 KLRK1 RTL8B RTL8A

4.54e-051721015979fd7b435f59b8a4d290a809cf76147d4c63d48
ToppCellfacs-Marrow-KLS-18m-Myeloid-monocyte_+_promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAM23 CYP27A1 KLRK1 RTL8B RTL8A

4.54e-051721015f4d7f416802218ce56408fa4cb8a555d846bc85b
ToppCelldroplet-Mammary_Gland-nan-3m-Endothelial-nan|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC38A4 IFI44 ADGRF5 HCFC2 NFAT5

4.66e-051731015fbc8ed566ea36c39c258dd6b3823c82f5d6eb17f
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c08-IL2RB|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

CRB1 KLRK1 CCNT2 KLRD1 SORL1

5.48e-051791015db76edd368eeca05a2a5d407c3eb2f535ade0ce3
ToppCelldroplet-Marrow-nan-3m-Hematologic-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LYST KLRK1 CD226 TET1 KLRD1

5.93e-051821015e78ba2c5cae480c16a596ce7c3bf2d480becacf4
ToppCelldroplet-Marrow-nan-3m-Hematologic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LYST KLRK1 CD226 TET1 KLRD1

5.93e-0518210151710eab3037a87609d21838be2d2d29c3bc36651
ToppCellILEUM-inflamed-(1)_T_cell-(1)_CD8_Trm|(1)_T_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

PDE4D CD226 PCNX1 KLRD1 GOLGB1

6.25e-051841015cef3ee2a4a0af961aa3b4c92150d423e841ae8c1
ToppCellControl-T_cells-NK_cells|Control / group, cell type (main and fine annotations)

KLRK1 LRFN2 CD226 KLRD1 SORL1

6.41e-051851015755c0998c729f462399f1d5e88adf4bfae31be30
ToppCelldroplet-Lung-LUNG-30m-Endothelial-Vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC38A4 CH25H IFI44 ADGRF5 FOXC1

6.57e-05186101541f1674afc17661eccaa779cdeb663db5e45685d
ToppCelldroplet-Lung-LUNG-30m-Endothelial-vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC38A4 CH25H IFI44 ADGRF5 FOXC1

6.57e-051861015aa006650cf21a2c51dfe1091681f67fdad939107
ToppCellSmart-seq2-lymph_node_(Smart-seq2)-lymphocytic-T_lymphocytic-effector_CD4-positive,_alpha-beta_T_cell|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ADAM23 WNK1 CD226 PCNX1 SORL1

6.74e-051871015e61c1755531469dd3850c9740474b5ad4e0499c1
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PDE4D SLC38A4 WNK1 TOX3 SORL1

6.74e-051871015b7689e7f6511920cd2beff27389555fddf685f61
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PDE4D ADAM23 FREM1 GPR160 TOX3

6.91e-05188101558ccb31cdf43167872ef0fc737e6f9c51ee2e060
ToppCellILEUM-inflamed-(1)_Cytotoxic_CD8_Trm|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

PDE4D LYST KLRK1 CD226 KLRD1

6.91e-051881015d26894d1066a70e4b32ae41fff1c4718f2591ba9
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PDE4D WNK1 FREM1 TOX3 NFAT5

6.91e-0518810154154f4787483c7e076e87a187733a9f666742c3d
ToppCellhuman_hepatoblastoma-Tumor_cells-T5|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

PDE4D ADAM23 FREM1 SLIT3 KCNMA1

6.91e-051881015b070a0667f1ee9b825b267b6c389b7c42fc436f9
ToppCelldroplet-Limb_Muscle-nan-18m-Endothelial|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PKP4 CH25H STING1 ADGRF5 RTL8A

7.09e-051891015a3f6ebd1622d36d114e42f6e0618d7b2fe8b9a2f
ToppCelldroplet-Limb_Muscle-Pre-Sort-18m-Endothelial-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PKP4 CH25H STING1 ADGRF5 FOXC1

7.09e-051891015d9c2adbbe3e40eb8d57200b6411533e6685ea0d2
ToppCelldroplet-Limb_Muscle-nan-18m-Endothelial-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PKP4 CH25H STING1 ADGRF5 RTL8A

7.09e-051891015d86455cf20769d70d62e2c1dd92cbc93c67aada5
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PDE4D WNK1 FREM1 TOX3 NFAT5

7.09e-05189101590aae7e806882bebfad78a78e9a16cf56af3ecd4
ToppCelldroplet-Limb_Muscle-Pre-Sort-18m-Endothelial-endothelial_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PKP4 CH25H STING1 ADGRF5 FOXC1

7.09e-051891015476226787c8ea0c9834a6f4c99ac7091cc20a455
ToppCelldroplet-Limb_Muscle-Pre-Sort-18m-Endothelial|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PKP4 CH25H STING1 ADGRF5 FOXC1

7.09e-0518910153fe69bad6427e41b8d2dae450828cc21e9c3b3ad
ToppCelldroplet-Limb_Muscle-nan-18m-Endothelial-endothelial_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PKP4 CH25H STING1 ADGRF5 RTL8A

7.09e-05189101584036d1257f6b18f47cfc7ac5e6ed6ea3553c235
ToppCellCOVID-19-T_cells-NK_cells|COVID-19 / group, cell type (main and fine annotations)

KLRK1 LRFN2 CD226 KLRD1 SORL1

7.09e-051891015b699152dfbb8cd8ed724e1e5a51838f29b681b62
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PDE4D FREM1 TOX3 ADGRF5 NFAT5

7.27e-051901015b3bccf4dd95e986db3cee324a6737f5fcc22e8e5
ToppCellCD8+_Memory_T_cell-CV-7|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster

LYST CCNT1 CCNT2 PRKDC NFAT5

7.45e-0519110159454f642c3621370fa23640b631301346b300950
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c04-ANXA2|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PDE4D ADAM23 CD226 PCNX1 SORL1

7.45e-0519110159c747f8cc1cdce45e839b661d782e1e8cfb79578
ToppCellHealthy_Control-Lymphoid-T-CD8_T|Healthy_Control / Condition, Lineage, Cell class and cell subclass

PDE4D KLRK1 RESF1 CD226 KLRD1

7.64e-05192101536b6ea21b0b1342f2dcac4dcaf359b6c772203f7
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.4.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PDE4D SLC26A9 GPR160 PEBP4 ADGRF5

7.82e-051931015043dd0fc2f93e0bd1ca34ac3e196622b3e91df0f
ToppCellhuman_hepatoblastoma|World / Sample and Cell Type and Tumor Cluster (all cells)

PDE4D WNK1 TOX3 NFAT5 GOLGB1

7.82e-051931015e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PDE4D SLC38A4 GPR160 TOX3 SORL1

8.02e-051941015be869e186386d03ebb670971dd24fa656b4b0edf
ToppCell5'-Adult-SmallIntestine-Epithelial-mature_enterocytic-Paneth|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SI APOB LGR5 FREM1 GPR160

8.02e-0519410152f6e62a4ec8707bd5a16c0734c5131af55207ea2
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c03-GZMK|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

PDE4D WNK1 LYST KLRK1 KLRD1

8.02e-051941015b0a7f5ca0c6f4f5764a8b35b5de80d82b828c66c
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4|GI_small-bowel / Manually curated celltypes from each tissue

PDE4D ADAM23 IFI44 STING1 SORL1

8.02e-0519410154547b57669be5d4f0de55175802ee04372288a6a
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

PDE4D SLC26A9 GPR160 PEBP4 ADGRF5

8.02e-05194101597534c8bba895a7913665e03ae4e5c4a6ad71daf
ToppCellcellseq-Epithelial-Epithelial_Alveolar-AT2-AT2|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

PDE4D SLC26A9 GPR160 PEBP4 ADGRF5

8.21e-0519510156867f9c56ea27a17c8c4099aae0d79903c3748a5
ToppCellTracheal-10x3prime_v2-Immune_Lymphocytic-T-T_CD8-CD8_TRM|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

KLRK1 RESF1 CD226 GNB5 KLRD1

8.21e-051951015c75d04b15d9f95fe2b5650cd4a5a376776610000
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PDE4D SLC26A9 GPR160 PEBP4 ADGRF5

8.21e-051951015d9694db6bf239636d1335016878c98f6ee2eb0eb
ToppCellmyeloid-Monocyte-CD14+_Monocyte|myeloid / Lineage, cell class and subclass

CYP27A1 F5 PCNX1 CARS2 KIF13A

8.21e-05195101515ba9c5f6ecb6ae2c603e6b036eb92b00b46f13f
ToppCellcellseq-Epithelial-Epithelial_Alveolar-AT2|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

PDE4D SLC26A9 GPR160 PEBP4 ADGRF5

8.21e-051951015955a0a7244cd7eaf006a39e1bd03333baf6f30a4
ToppCellControl-Lymphoid-T|Lymphoid / Disease state, Lineage and Cell class

CH25H FYCO1 STING1 CD226 PCNX1

8.21e-0519510156687e579582d7a239bee80846de0cf827a6f6a62
ToppCellASK440-Epithelial-Type_2|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq

PDE4D SLC26A9 PEBP4 ADGRF5 NNMT

8.41e-051961015754b4202b617165c6994a0b5a9b1e486dccdd44d
ToppCelldistal-Epithelial-Alveolar_Epithelial_Type_2-1|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SLC26A9 CITED1 GPR160 PEBP4 NNMT

8.83e-05198101519eefd05573fbaed654af52bf0f8a26092b8b229
ToppCellAT2_cells|World / lung cells shred on cell class, cell subclass, sample id

PDE4D GPR160 PEBP4 ADGRF5 NNMT

8.83e-05198101592c569c3b8a9fca2d4682cbf77ee8149bcc0a80a
ToppCellAT2_cells-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

PDE4D GPR160 PEBP4 TOX3 ADGRF5

8.83e-051981015893036558a9ad86b57f9e735df35812e9d18739e
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-lymphocytic-T_lymphocytic-CD8-positive,_alpha-beta_T_cell|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

PDE4D KLRK1 RESF1 CD226 KLRD1

8.83e-051981015162881a04a981741a0e26e32e0c3c694282701c6
ToppCellmild-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

TTC14 IFI44 CCNT1 CD226 GOLGB1

9.04e-051991015f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCellBAL-Control-Lymphocyte-T/NK|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PDE4D KLRK1 RESF1 CD226 KLRD1

9.04e-05199101555f23aef431fc1965d2442ff9c7b32ee33bc0d69
ToppCellmild-MAIT|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

PDE4D IFI44 ZDBF2 RESF1 GOLGB1

9.04e-051991015cbe1fb6d2c5fca7a1baf1ad20afcdf8e8e11bd84
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PDE4D WNK1 FREM1 TOX3 NFAT5

9.04e-0519910153cd6383c50ce342fe5c175e2e50784d634a90e80
ToppCellLPS_IL1RA-Endothelial-Endothelial-Gen_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

PKP4 RESF1 TOX3 ADGRF5 CTNND1

9.25e-052001015dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCellbackground-Hepatocytes|background / Sample and Cell Type and Tumor Cluster (all cells)

SLC38A4 CYP27A1 APOB F5 NNMT

9.25e-052001015787d35b5c2f2ad967ae14e99496a0299ac7e72fd
ToppCellTracheal|World / Cell types per location group and 10X technology with lineage, and cell group designations

PKP4 TET1 SLIT3 TOX3 KCNMA1

9.25e-052001015682960e28542a3d6c119047cd0131941932cfdea
ToppCellLPS_only-Endothelial-Endothelial-Gen_Cap|LPS_only / Treatment groups by lineage, cell group, cell type

PKP4 IFI44 TOX3 ADGRF5 CTNND1

9.25e-052001015eb94a5111ef0e903ee5be9f7efe571b4e6d5fce1
ToppCellmild-gd_T|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

PDE4D KLRK1 RESF1 CD226 KLRD1

9.25e-052001015109f673a4967ffa52270a0b4f818b3461288db44
ToppCellmedial-Endothelial-Vein-2|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ADAM23 NMUR2 BDKRB2 NNMT FOXC1

9.25e-0520010153f689029f5bc7db0af50a405f1e252aeec529077
ToppCelldistal-2-Endothelial-Vein|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ADAM23 NMUR2 BDKRB2 NNMT FOXC1

9.25e-0520010152785225956d2422acab90e99b7debe3709cf3308
ToppCellmedial-Endothelial-Vein|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ADAM23 NMUR2 BDKRB2 NNMT FOXC1

9.25e-0520010151163e5f6dfb304c94bf8885629350454f4b6bee8
ToppCellmedial-2-Endothelial-Vein|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ADAM23 NMUR2 BDKRB2 NNMT FOXC1

9.25e-05200101549da4e3ff10262a492c2cf566a7f2e35e418bfda
ToppCell10x5'-Lung-Lymphocytic_T_CD4-Tfh|Lung / Manually curated celltypes from each tissue

ADAM23 CH25H ZDBF2 TET1

2.46e-041341014da3cb572d0c19932619e51e272c0555e91b482ac
ToppCellRA-15._Ventricular_Cardiomyocyte_III|RA / Chamber and Cluster_Paper

PDE4D MUC12 LRFN2 FOXC1

2.46e-04134101460ee3accc54108e5b9a0018f6aa8488dc39d5ade
ToppCellfacs-Limb_Muscle-forelimb_and_hindlimb-18m-Endothelial|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PEBP4 MEIOC ADGRF5 CNGA4

2.67e-041371014b831d917f5073ccff158662adb281d34f023126a
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Connecting_Tubule_Intercalated_Cell_Type_A|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

WNK1 FREM1 MEIOC ADGRF5

2.67e-04137101481cdb216e6c81acf9c2072f9d39e1a42612e1258
ToppCellfacs-Limb_Muscle-forelimb_and_hindlimb-18m-Endothelial-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PEBP4 MEIOC ADGRF5 CNGA4

2.67e-041371014cf3e928d9a7a7349840bb87475a42a07f65b94f0
ToppCellfacs-Limb_Muscle-forelimb_and_hindlimb-18m-Endothelial-endothelial_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PEBP4 MEIOC ADGRF5 CNGA4

2.67e-0413710145d82d6c7eef4ec7a7fae60e37fb956488314987e
ToppCellRA-15._Ventricular_Cardiomyocyte_III|World / Chamber and Cluster_Paper

PDE4D MUC12 LRFN2 FOXC1

2.75e-0413810145a713f24f633de463ef47ca37fbb2bb60c7fdb77
ToppCellThalamus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Gata3_(Periacqueductal_gray_(PAG)_(or_adjacent_APTD))--|Thalamus / BrainAtlas - Mouse McCarroll V32

NMUR2 KLRK1 MEIOC

2.94e-045710139614fe2acc6ee039383504f94bbe6d35aac27f25
ToppCellThalamus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Gata3_(Periacqueductal_gray_(PAG)_(or_adjacent_APTD))|Thalamus / BrainAtlas - Mouse McCarroll V32

NMUR2 KLRK1 MEIOC

2.94e-04571013309b3d48bfe215d7b581722c06d444b5b2ef6a30
ToppCellThalamus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Gata3_(Periacqueductal_gray_(PAG)_(or_adjacent_APTD))-|Thalamus / BrainAtlas - Mouse McCarroll V32

NMUR2 KLRK1 MEIOC

2.94e-045710133c55a5598a7ea789500f2fbd35c79d2b97a3fc7d
ToppCellfacs-Heart-Unknown-3m-Endothelial-endothelial_cell_of_coronary_artery|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EFCAB5 SLC26A9 KCNMA1 TDRD12

2.98e-0414110144aa4b3476dc5abefbd348353cfe711cd5fe3d52f
ToppCellfacs-Heart-Unknown-3m-Endothelial-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EFCAB5 SLC26A9 KCNMA1 TDRD12

2.98e-041411014e40c6f1b7fbaa46b3eaa55f1b37ef360b04370a8
ToppCellfacs-Heart-Unknown-3m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EFCAB5 SLC26A9 KCNMA1 TDRD12

3.06e-041421014759fbbd15b4fb313bd6269b7f087edafebd530ef
ToppCell3'_v3-Lung-Lymphocytic_T_CD4-Tfh|Lung / Manually curated celltypes from each tissue

ADAM23 CH25H LRTM2 RESF1

3.06e-041421014319812c84fad93276bf093f2ad78db02ae745bf4
ToppCelldroplet-Liver-Hepatocytes-24m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC38A4 APOB NNMT SERPINA7

3.32e-041451014f142b86d4da5b71c189da46cbc4beebdc387ffee
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

F5 LRFN2 SLIT3 CNGA4

3.49e-041471014989a48bda98fbff398985397a6b1189a4cbc80e7
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

F5 LRFN2 SLIT3 CNGA4

3.49e-041471014f6681c849c4c06154548bd29a094f202d1c946c2
ToppCellEntopeduncular-Macroglia-OLIGODENDROCYTE-O2-Trf-Oligodendrocyte.Trf.Klk6_(Klk6)-|Entopeduncular / BrainAtlas - Mouse McCarroll V32

SLC26A9 BDKRB2 MEIOC

3.77e-0462101363bf0f86941cbfcac4747cc56fb9a45c8bfc9957
ToppCellEntopeduncular-Macroglia-OLIGODENDROCYTE-O2-Trf-Oligodendrocyte.Trf.Klk6_(Klk6)|Entopeduncular / BrainAtlas - Mouse McCarroll V32

SLC26A9 BDKRB2 MEIOC

3.77e-046210130d33612f6f50f4560ff688d1a0ffb7ce444817a9
ToppCelldroplet-Liver-Hepatocytes-24m-Epithelial-hepatocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC38A4 APOB NNMT SERPINA7

3.87e-041511014e243b6c76e59035f10519a86399b598dd2123f87
ToppCelldroplet-Liver-Hepatocytes-24m-Epithelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC38A4 APOB NNMT SERPINA7

3.87e-041511014cdd2ce0969da446616627e3569bbe5a5d9b475bd
DrugMoxalactam disodium salt [64953-12-4]; Down 200; 7uM; HL60; HT_HG-U133A

RANGAP1 PKP4 MORC2 LYST VPS13D SLITRK5 PCNX1 HCFC2

2.38e-0619310183028_DN
DrugFolic acid [59-30-3]; Down 200; 9uM; HL60; HG-U133A

RANGAP1 ADAM23 CNTRL OCRL MORC2 WNK1 VPS13D GNB5

2.67e-0619610181790_DN
DiseaseHereditary Motor and Sensory-Neuropathy Type II

MORC2 WNK1 FIG4

9.62e-0613973C0270914
Diseaseisolated growth hormone deficiency type II (implicated_via_orthology)

CSH1 CSH2

1.06e-045972DOID:0060872 (implicated_via_orthology)
Diseaseisolated growth hormone deficiency (implicated_via_orthology)

CSH1 CSH2

2.22e-047972DOID:0060870 (implicated_via_orthology)
DiseaseHereditary Motor and Sensory Neuropathy Type I

MORC2 FIG4

2.96e-048972C0751036
DiseaseRoussy-Levy Syndrome (disorder)

MORC2 FIG4

2.96e-048972C0205713
DiseaseCharcot-Marie-Tooth Disease, Type Ib

MORC2 FIG4

2.96e-048972C0270912
DiseaseCharcot-Marie-Tooth Disease, Type Ia (disorder)

MORC2 FIG4

2.96e-048972C0270911
Diseasecongenital diaphragmatic hernia (implicated_via_orthology)

FREM1 SLIT3

6.91e-0412972DOID:3827 (implicated_via_orthology)
DiseaseCharcot-Marie-Tooth Disease

MORC2 FIG4

6.91e-0412972C0007959
Diseaseesophageal squamous cell carcinoma

PDE4D STING1

8.15e-0413972EFO_0005922
DiseaseMetabolic Bone Disorder

CYP27A1 KCNMA1

9.49e-0414972C0005944
Diseasecongenital hypothyroidism (biomarker_via_orthology)

CSH1 CSH2

9.49e-0414972DOID:0050328 (biomarker_via_orthology)
DiseaseOsteopenia

CYP27A1 KCNMA1

1.09e-0315972C0029453
Diseasetriacylglycerol 50:5 measurement

LRTM2 YIPF5

1.25e-0316972EFO_0010412
Diseaseamino acid measurement

PDE4D PEBP4 CCNT2 OSBPL2 SLIT3 KCNMA1 PRKDC CAMTA1

1.79e-03678978EFO_0005134
Diseasesusceptibility to mumps measurement

PDE4D BDKRB2 KCNMA1

1.96e-0375973EFO_0008404
DiseaseDeep Vein Thrombosis

F5 F8

2.16e-0321972C0149871
DiseaseVenous Thrombosis

F5 F8

2.16e-0321972C0042487
Diseaseosteoporosis (biomarker_via_orthology)

CSH1 CSH2

2.37e-0322972DOID:11476 (biomarker_via_orthology)
Diseaseproprotein convertase subtilisin/kexin type 9 measurement

IFI44 APOB

2.37e-0322972EFO_0009312
Diseaseresponse to clopidogrel, cardiovascular event measurement

FREM1 R3HCC1L

2.59e-0323972EFO_0006919, GO_1903493
Diseasecongenital diaphragmatic hernia (biomarker_via_orthology)

FREM1 SLIT3

2.82e-0324972DOID:3827 (biomarker_via_orthology)
Diseasediacylglycerol 34:2 measurement

LRTM2 YIPF5

3.05e-0325972EFO_0010353

Protein segments in the cluster

PeptideGeneStartEntry
STQMNSYSDSGYQEA

PKP4

146

Q99569
MASTDYSTYSQAAAQ

EWSR1

1

Q01844
DVITQIASFMAYSNS

BDKRB2

311

P30411
SKDLAQTSYFMATNS

CCNT2

166

O60583
QQMAKEAYSSSAAAV

CAMTA1

541

Q9Y6Y1
NMFATESYIIDSAQA

CNTRL

396

Q7Z7A1
NSSSNISYSNAMQKE

ADAM23

96

O75077
DDYSFNNTMAQSGCL

CATSPERE

791

Q5SY80
NMTSQAFEAYSLTDS

ARGFX

286

A6NJG6
NYSTSSNSMNGYSNV

EBF2

471

Q9HAK2
ASKDLAQTSYFMATN

CCNT1

166

O60563
SNYNTFLDSELSMLN

R3HCC1L

481

Q7Z5L2
ALMQKAFNSSSFNSN

RANGAP1

496

P46060
NYLSACSFTNSDMQI

GNB5

196

O14775
QAAFLSQASQMYDSS

NIPAL3

256

Q6P499
YQAASSDSSAAPNMQ

HCFC2

396

Q9Y5Z7
SVLDSLMSATYFNDN

KCNMA1

1041

Q12791
ALSSEQMSRTNYQSF

NMUR2

396

Q9GZQ4
DEIQSFMANNQSFYS

GGNBP2

646

Q9H3C7
SSYLQTQEMVSNFDL

FYCO1

206

Q9BQS8
SMFANNLVYDTSDSD

CSH2

121

P0DML3
LTISLNSSNYAFMQA

GDF3

301

Q9NR23
YSITDNSAASMLQVF

PCNX1

1676

Q96RV3
SAYNMANSFTFTRSL

PLXNA3

1581

P51805
MAIFNNTTSSSSNFL

OR51T1

1

Q8NGJ9
NTNSELALMYNDSSV

PDE4D

516

Q08499
ASTQFMTQNYQDSPT

PEBP4

191

Q96S96
SYSSTMANNEGLFSL

NNMT

241

P40261
YESQASCMSQNASLL

KLRK1

121

P26718
TGAMDSQNQDSFTFY

FREM1

1356

Q5H8C1
AQKNYMAFLDSQTAT

ELP1

1116

O95163
DAQITASSYFTNMFA

F8

2206

P00451
MAASQQQASAASSAA

MED29

1

Q9NX70
SNFSNMSTSSYNDNT

NFAT5

181

O94916
MAFTNYSSLNRAQLT

MORC2

1

Q9Y6X9
MTALSSENCSFQYQL

GPR160

1

Q9UJ42
FSSLAFDNSGMDNYI

DNAJB7

171

Q7Z6W7
FNTDSMTLNNTAYLL

EFCAB5

161

A4FU69
ASAIDMSTNYNSDSL

APOB

1876

P04114
MSTNYNSDSLHFSNV

APOB

1881

P04114
FDASSIQYFSSQMIV

IFI44

311

Q8TCB0
MRAADQFDIYSSQQS

C5orf24

26

Q7Z6I8
MQTLSRYYSNAFSDA

FIG4

571

Q92562
NSSCQMAFPSSQSLY

FOXC1

526

Q12948
SASGNQVSDMAQLFY

CYP27A1

196

Q02318
NSAMQYSFVSANEAP

CCP110

746

O43303
LQSAASNPFYFSQAM

LYST

416

Q99698
MDANSQFTSTYILTA

MCHR1

191

Q99705
AAQAAVASYNMGSNS

CST6

51

Q15828
EMASYFNSSSVNEFA

ERCC6L2

1241

Q5T890
AERVYFLNSTMASNN

CD226

76

Q15762
QLQSGNSFYMLSLTS

CRB1

1011

P82279
NSFYMLSLTSLQSVN

CRB1

1016

P82279
SMFANNLVYDTSDSD

CSH1

121

P0DML2
NSSMIFYANDTGAQQ

SLC38A9

266

Q8NBW4
TAAAMYQATRIFASN

BYSL

226

Q13895
HQNSSSFALATQYMS

CH25H

161

O95992
SNMGSNTKSLDNNYS

CTNND1

891

O60716
VFTSYLDLSMNNISQ

LGR5

66

O75473
NQLDMSDYSSSYQDV

KIF13A

1411

Q9H1H9
QTSSYMFVDENTFSN

RTL8A

46

Q9BWD3
QTSSYMFVDENTFSN

RTL8B

46

Q17RB0
SQQAFYSDESVSAME

MEIOC

191

A2RUB1
QTLFAMSQYSQAGFS

STING1

266

Q86WV6
SAMNITAYLGNTTDN

SORL1

2066

Q92673
SAIDYSDSAMLQAQQ

CARS2

351

Q9HA77
SVASLASYMPQSNNC

SLC6A16

356

Q9GZN6
FNNATNESYVDTAAM

SLC26A9

151

Q7LBE3
STRNVMYFNGNSDAS

F5

2011

P12259
MFNYCSQLEDENSSA

LRTM2

246

Q8N967
AMYNNLDVSQDTLFT

RIF1

1081

Q5UIP0
SSNKMTASYEQASQE

RESF1

1306

Q9HCM1
NSAMNDFYNSTCQDI

TDRD12

36

Q587J7
QFQYVMQAGNAASSS

TBX15

476

Q96SF7
SLQHMQYNAQYSSAS

NKX2-2

241

O95096
NQPMNAHSNFTYDAS

SI

896

P14410
NNSESSDVNFMMDYT

SLC38A4

276

Q969I6
NYFLVNLAFSDASMA

TACR3

121

P29371
NLAFSDASMAAFNTL

TACR3

126

P29371
EYNSVNANMIATLFT

OCRL

851

Q01968
PNSAQMYNFTSFTVS

OSBPL2

371

Q9H1P3
GAMVSSNSALQFVNY

SLC35B1

96

P78383
STVDSAQKNFNDYAM

TET1

1386

Q8NFU7
SSRFSIYTALFNNMT

ADGRF5

316

Q8IZF2
DANQEMSSVAYSNLA

CITED1

21

Q99966
SSVIYNMNTADAAFY

CNGA4

266

Q8IV77
DLSNNSISMLTNYTF

SLIT3

781

O75094
STNNSDVSSFNMQYS

SLITRK5

701

O94991
NATLYKMSSINADFA

SERPINA7

36

P05543
YQSANSSSMNGLSSL

ZHX1

726

Q9UKY1
NFNVDASDQSMTYES

ZDBF2

1626

Q9HCK1
SNSLESYENVMQSSL

TTC14

241

Q96N46
YMNMAEANNAFFAAS

TOX3

36

O15405
MSGFENLNTDFYQTS

YIPF5

1

Q969M3
SSEYFQALVNNMSFV

PRKDC

2296

P78527
MQSYASAMLSVFNSD

SRY

1

Q05066
SQASSSDKANMLQEY

ZNF148

591

Q9UQR1
LSQSLSNSFNSSYMS

WNK1

2046

Q9H4A3
NYNSQSLMDAFSCSL

ZFYVE9

171

O95405
SSYQNSSGLMDAFNS

VPS13D

2546

Q5THJ4
DSYNQVQSFSKAMAS

GOLGB1

2826

Q14789
NTDELDFMSSSQQFY

KLRD1

101

Q13241
KMNDASSQEYQNFST

MUC12

5186

Q9UKN1
SKMAAAVSNVYSQTN

LRFN2

566

Q9ULH4