Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionglucokinase activity

HK2 HK3 GCK

3.06e-0651363GO:0004340
GeneOntologyMolecularFunctionhexokinase activity

HK2 HK3 GCK

3.06e-0651363GO:0004396
GeneOntologyMolecularFunctionfructokinase activity

HK2 HK3 GCK

3.06e-0651363GO:0008865
GeneOntologyMolecularFunctioncarbohydrate binding

HK2 MAN2B1 HK3 SI GCK GALNT16 CD209 PKD1 CLEC3B MGAM2

5.33e-0531013610GO:0030246
GeneOntologyMolecularFunctionD-glucose binding

HK2 HK3 GCK

1.06e-04141363GO:0005536
GeneOntologyMolecularFunctionmyosin VI binding

TOM1 IQGAP3

1.38e-0431362GO:0070853
GeneOntologyMolecularFunctionlipase activity

GPLD1 PNPLA5 ABHD4 LIPA SMPDL3A PLA2G4F

3.68e-041381366GO:0016298
GeneOntologyMolecularFunctioncarbohydrate kinase activity

HK2 HK3 GCK

3.76e-04211363GO:0019200
GeneOntologyMolecularFunctionalpha-1,4-glucosidase activity

SI MGAM2

4.54e-0451362GO:0004558
GeneOntologyMolecularFunctionmonosaccharide binding

HK2 MAN2B1 HK3 GCK CD209

4.83e-04951365GO:0048029
GeneOntologyMolecularFunctionhydrolase activity, hydrolyzing O-glycosyl compounds

MAN2B1 SI GLB1L2 NAGPA MGAM2

6.98e-041031365GO:0004553
GeneOntologyMolecularFunctioncarboxylic ester hydrolase activity

PNPLA5 ABHD4 LIPA AARS2 CES4A PLA2G4F

7.28e-041571366GO:0052689
GeneOntologyMolecularFunctionalpha-glucosidase activity

SI MGAM2

9.46e-0471362GO:0090599
GeneOntologyBiologicalProcesscarbohydrate phosphorylation

HK2 HK3 GCK TKFC

2.00e-05251354GO:0046835
GeneOntologyBiologicalProcessnuclear transport

IPO5 SMG1 AHCYL1 NUP107 YWHAE MDN1 PKD1 ELAVL1 AKAP13 NOTCH1 AGAP3

3.99e-0537813511GO:0051169
GeneOntologyBiologicalProcessnucleocytoplasmic transport

IPO5 SMG1 AHCYL1 NUP107 YWHAE MDN1 PKD1 ELAVL1 AKAP13 NOTCH1 AGAP3

3.99e-0537813511GO:0006913
GeneOntologyCellularComponentextracellular matrix

GPLD1 RELN COL27A1 TECTA MMP20 GPC6 LRIG3 TGM3 FREM2 DST PCSK6 CSPG4 COL14A1 CLEC3B

1.06e-0465613714GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

GPLD1 RELN COL27A1 TECTA MMP20 GPC6 LRIG3 TGM3 FREM2 DST PCSK6 CSPG4 COL14A1 CLEC3B

1.10e-0465813714GO:0030312
MousePhenoabnormal jaw morphology

SOX11 SMG1 DYNC2H1 FOXN4 NPEPPS COL27A1 MINK1 AGAP11 MMP20 MSX2 AKAP9 WDR11 PCSK6 PKD1 EIF3K DNAH5 KAT14

1.49e-0653011517MP:0000454
MousePhenoabnormal cranium morphology

SOX11 SMG1 DYNC2H1 FOXN4 NPEPPS COL27A1 DPCD MINK1 AGAP11 MMP20 GPC6 MSX2 LRIG3 FREM2 AKAP9 WDR11 PCSK6 PKD1 EIF3K DNAH5 KAT14

2.55e-0681311521MP:0000438
MousePhenoabnormal craniofacial bone morphology

SOX11 SMG1 DYNC2H1 FOXN4 NPEPPS COL27A1 DPCD MINK1 AGAP11 MMP20 GPC6 MSX2 LRIG3 FREM2 AKAP9 WDR11 PCSK6 PKD1 EIF3K DNAH5 KAT14

3.33e-0682711521MP:0002116
MousePhenoabnormal facial morphology

SOX11 SMG1 DYNC2H1 FOXN4 NPEPPS COL27A1 DPCD MINK1 AGAP11 MMP20 GPC6 MSX2 LRIG3 FREM2 DST AKAP9 WDR11 PCSK6 RAB3GAP2 EIF3K DNAH5 KAT14

4.17e-0691011522MP:0003743
MousePhenoabnormal viscerocranium morphology

SOX11 SMG1 DYNC2H1 FOXN4 NPEPPS COL27A1 MINK1 AGAP11 MMP20 MSX2 AKAP9 WDR11 PCSK6 PKD1 EIF3K DNAH5 KAT14

6.73e-0659311517MP:0005274
MousePhenoabnormal hippocampus CA2 region morphology

SOX11 RELN MAN2B1

1.07e-0561153MP:0008265
MousePhenoabnormal head morphology

SOX11 SMG1 DYNC2H1 FOXN4 NPEPPS COL27A1 DPCD MINK1 MAGEE2 AGAP11 MMP20 GPC6 MSX2 LRIG3 FREM2 DST AKAP9 WDR11 PCSK6 RAB3GAP2 EIF3K DNAH5 KAT14

3.47e-05112011523MP:0000432
MousePhenodelaminated cerebellar granule layer

RELN MSX2

6.71e-0521152MP:0000887
MousePhenoabnormal respiratory system morphology

SOX11 SMG1 EPRS1 FAT4 FBXW9 DYNC2H1 SYNE1 COL27A1 DPCD TNRC6C GPC6 PARP6 FREM2 LIPA WDR11 ASAH1 SERPINB4 PCSK6 PKD1 PINX1 DNAH5

8.58e-05102711521MP:0002132
MousePhenoabnormal craniofacial morphology

SOX11 SMG1 DYNC2H1 FOXN4 NPEPPS COL27A1 DPCD MINK1 AGAP11 MMP20 GPC6 MSX2 LRIG3 FREM2 DST AKAP9 WDR11 PCSK6 RAB3GAP2 PKD1 EIF3K AKAP13 DNAH5 KAT14 NOTCH1

1.07e-04137211525MP:0000428
MousePhenocraniofacial phenotype

SOX11 SMG1 DYNC2H1 FOXN4 NPEPPS COL27A1 DPCD MINK1 AGAP11 MMP20 GPC6 MSX2 LRIG3 FREM2 DST AKAP9 WDR11 PCSK6 RAB3GAP2 PKD1 EIF3K AKAP13 DNAH5 KAT14 NOTCH1

1.07e-04137211525MP:0005382
MousePhenoabnormal axial skeleton morphology

SOX11 SMG1 FAT4 DYNC2H1 FOXN4 NPEPPS SYNE1 COL27A1 DPCD MINK1 AGAP11 MMP20 GPC6 MSX2 LRIG3 FREM2 AKAP9 WDR11 ASAH1 PCSK6 PKD1 EIF3K CLEC3B DNAH5 KAT14 NOTCH1

1.08e-04145811526MP:0002114
MousePhenoabnormal mouth morphology

SOX11 SMG1 DYNC2H1 FOXN4 NPEPPS COL27A1 MINK1 AGAP11 MMP20 GPC6 MSX2 DST AKAP9 WDR11 EIF3K KAT14

1.16e-0467011516MP:0000452
MousePhenodystrophic muscle

B4GAT1 SYNE1 ASAH1 TLN2

1.31e-04321154MP:0000752
MousePhenoabnormal eye development

SMG1 MYO7A AGAP11 STK35 MSX2 FREM2 GJA8 DST WDR11 PCSK6 RAB3GAP2 LSS KAT14

1.64e-0448211513MP:0001286
MousePhenoabnormal lung morphology

SOX11 SMG1 EPRS1 FAT4 DYNC2H1 SYNE1 COL27A1 TNRC6C PARP6 FREM2 LIPA WDR11 ASAH1 PCSK6 PKD1 PINX1 DNAH5

1.72e-0476711517MP:0001175
MousePhenoabnormal cornea morphology

AHCYL1 MAN2B1 DSG1 AGAP11 STK35 MSX2 FREM2 GJA8 PCSK6 KAT14 NOTCH1

2.13e-0436611511MP:0001312
MousePhenoabnormal brain development

SOX11 SMG1 RELN WDR4 B4GAT1 DYNC2H1 DPCD MSX2 FREM2 WDR11 ASAH1 PCSK6 PKD1 AFDN DNAH5

2.28e-0463811515MP:0000913
MousePhenoabnormal interatrial septum morphology

FAT4 DYNC2H1 FREM2 PCSK6 PKD1 DNAH5

2.50e-041071156MP:0000282
MousePhenoabnormal tooth morphology

SMG1 FOXN4 NPEPPS MINK1 AGAP11 MMP20 MSX2 AKAP9 EIF3K KAT14

2.91e-0431811510MP:0002100
MousePhenoabnormal dental arch morphology

SMG1 FOXN4 NPEPPS MINK1 AGAP11 MMP20 MSX2 AKAP9 EIF3K KAT14

2.98e-0431911510MP:0030254
MousePhenochondrodystrophy

COL27A1 MSX2 PKD1

4.04e-04181153MP:0002657
DomainHexokinase_2

HK2 HK3 GCK

3.82e-0651373PF03727
DomainHexokinase_BS

HK2 HK3 GCK

3.82e-0651373IPR019807
DomainHexokinase_C

HK2 HK3 GCK

3.82e-0651373IPR022673
DomainHexokinase_N

HK2 HK3 GCK

3.82e-0651373IPR022672
DomainHexokinase_1

HK2 HK3 GCK

3.82e-0651373PF00349
DomainHEXOKINASE_2

HK2 HK3 GCK

3.82e-0651373PS51748
DomainHEXOKINASE_1

HK2 HK3 GCK

3.82e-0651373PS00378
DomainHexokinase

HK2 HK3 GCK

7.60e-0661373IPR001312
DomainAda2/TADA2

TADA2B TADA2A

5.34e-0521372IPR016827
DomainM_domain

TNRC6C TNRC6A

5.34e-0521372PF12938
DomainGW182_M_dom

TNRC6C TNRC6A

5.34e-0521372IPR026805
DomainATPase_dyneun-rel_AAA

DYNC2H1 MDN1 DNAH5

1.32e-04141373IPR011704
DomainAAA_5

DYNC2H1 MDN1 DNAH5

1.32e-04141373PF07728
DomainAgo_hook

TNRC6C TNRC6A

1.59e-0431372PF10427
DomainTNRC6_PABC-bd

TNRC6C TNRC6A

1.59e-0431372IPR032226
DomainArgonaute_hook_dom

TNRC6C TNRC6A

1.59e-0431372IPR019486
DomainTNRC6-PABC_bdg

TNRC6C TNRC6A

1.59e-0431372PF16608
DomainGal_mutarotase_SF_dom

MAN2B1 SI MGAM2

2.44e-04171373IPR011013
DomainGal_mutarotase_N

SI MGAM2

3.17e-0441372IPR031727
DomainNtCtMGAM_N

SI MGAM2

3.17e-0441372PF16863
DomainGlyco_hydro_31_AS

SI MGAM2

7.86e-0461372IPR030458
DomainLaminin_G

FAT4 COL27A1 CSPG4 COL14A1

8.65e-04581374IPR001791
DomainSANT_dom

MIER3 TADA2B TADA2A

8.87e-04261373IPR017884
DomainEGF_extracell

RELN TENM1 NAGPA NOTCH1

9.83e-04601374IPR013111
DomainEGF_2

RELN TENM1 NAGPA NOTCH1

9.83e-04601374PF07974
DomainGlyco_hydro_31

SI MGAM2

1.09e-0371372IPR000322
DomainPlectin

PPL DST

1.09e-0371372PF00681
DomainGlyco_hydro_31

SI MGAM2

1.09e-0371372PF01055
DomainPlectin_repeat

PPL DST

1.09e-0371372IPR001101
DomainGLYCOSYL_HYDROL_F31_1

SI MGAM2

1.09e-0371372PS00129
DomainPLEC

PPL DST

1.09e-0371372SM00250
DomainSANT

MIER3 TADA2B TADA2A

1.11e-03281373PS51293
DomainSpectrin_repeat

SYNE1 PPL DST

1.23e-03291373IPR002017
DomainDHC_N1

DYNC2H1 DNAH5

1.45e-0381372PF08385
DomainTrefoil

SI MGAM2

1.45e-0381372PF00088
DomainDynein_heavy_dom-1

DYNC2H1 DNAH5

1.45e-0381372IPR013594
DomainSPEC

SYNE1 PPL DST

1.64e-03321373SM00150
DomainSpectrin/alpha-actinin

SYNE1 PPL DST

1.64e-03321373IPR018159
DomainEGF

FAT4 RELN TECTA PCSK6 TENM1 NAGPA NOTCH1

1.76e-032351377SM00181
DomainP_TREFOIL_2

SI MGAM2

1.86e-0391372PS51448
DomainPD

SI MGAM2

1.86e-0391372SM00018
DomainMyb_DNA-binding

MIER3 TADA2B TADA2A

2.13e-03351373PF00249
DomainCENP-B_N

CENPB TIGD2

2.31e-03101372PF04218
DomainEGF-like_dom

FAT4 RELN TECTA PCSK6 TENM1 NAGPA NOTCH1

2.44e-032491377IPR000742
DomainLAM_G_DOMAIN

FAT4 COL27A1 CSPG4

2.70e-03381373PS50025
Domain-

SI MGAM2

2.81e-031113724.10.110.10
DomainP_trefoil_dom

SI MGAM2

3.36e-03121372IPR000519
DomainHTH_Psq

CENPB TIGD2

3.36e-03121372IPR007889
DomainHTH_PSQ

CENPB TIGD2

3.36e-03121372PS50960
DomainCENPB

CENPB TIGD2

3.36e-03121372SM00674
DomainDDE_1

CENPB TIGD2

3.36e-03121372PF03184
DomainDDE_SF_endonuclease_dom

CENPB TIGD2

3.36e-03121372IPR004875
DomainHTH_CENPB

CENPB TIGD2

3.95e-03131372PS51253
DomainHTH_Tnp_Tc5

CENPB TIGD2

3.95e-03131372PF03221
DomainHTH_CenpB_DNA-bd_dom

CENPB TIGD2

3.95e-03131372IPR006600
DomainDynein_heavy_chain_D4_dom

DYNC2H1 DNAH5

4.59e-03141372IPR024317
DomainDynein_HC_stalk

DYNC2H1 DNAH5

4.59e-03141372IPR024743
DomainDynein_heavy_dom-2

DYNC2H1 DNAH5

4.59e-03141372IPR013602
DomainDHC_N2

DYNC2H1 DNAH5

4.59e-03141372PF08393
DomainMT

DYNC2H1 DNAH5

4.59e-03141372PF12777
DomainAAA_8

DYNC2H1 DNAH5

4.59e-03141372PF12780
Domain-

CENPB MIER3 MSX2 TIGD2 ANHX TADA2B TADA2A

4.92e-0328313771.10.10.60
DomainDHC_fam

DYNC2H1 DNAH5

5.27e-03151372IPR026983
DomainDynein_heavy

DYNC2H1 DNAH5

5.27e-03151372PF03028
DomainDynein_heavy_dom

DYNC2H1 DNAH5

5.27e-03151372IPR004273
DomainSANT

MIER3 TADA2B TADA2A

5.88e-03501373SM00717
DomainWD40_repeat_dom

KNTC1 WDR4 FBXW9 WDR11 EIF2A WDR17 WDFY1

6.37e-032971377IPR017986
DomainSANT/Myb

MIER3 TADA2B TADA2A

6.56e-03521373IPR001005
DomainAcyl_Trfase/lysoPLipase

PNPLA5 PLA2G4F

6.76e-03171372IPR016035
DomainGlycoside_hydrolase_SF

SI GLB1L2 MGAM2

6.92e-03531373IPR017853
PathwayREACTOME_METABOLISM_OF_CARBOHYDRATES

HK2 MAN2B1 HK3 B4GAT1 NUP107 GCK GLB1L2 GPC6 TKFC CSPG4

5.46e-0527111110MM15406
PathwayWP_UDPDERIVED_SUGARS_SYNTHESIS_IN_FIBROBLASTS

HK2 HK3 GCK

7.49e-05111113M48094
PathwayREACTOME_METABOLISM_OF_CARBOHYDRATES

HK2 MAN2B1 HK3 B4GAT1 NUP107 GCK GLB1L2 GPC6 TKFC CSPG4

9.07e-0528811110M16864
Pubmed

Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.

KNTC1 MAGED1 DPCD NELFB FRYL YWHAE DENND4C DST AKAP9 TNRC6A AFDN NOTCH1 AGAP3

2.95e-084461381324255178
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

IPO5 USP34 EPRS1 AHCYL1 RELN MAGED1 ZNF473 WDR4 B4GAT1 SYNE1 YWHAE FAN1 DST PCSK6 PKD1 FBXO7 TLN2 AFDN WDR17 SDHA AGAP3

3.93e-0812851382135914814
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

USP34 MAN2B1 MYO7A FRYL TNRC6C ITPR2 MSX2 TKFC DST MDN1 INF2 CSPG4 PKD1 TLN2 AKAP13 IQGAP3 NOTCH1 SDHA AGAP3

8.52e-0811051381935748872
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

IPO5 KNTC1 EPRS1 HK2 NUP107 DSG1 DYNC2H1 NPEPPS SYNE1 YWHAE TGM3 MDN1 GTF3C1 RAB3GAP2 ELAVL1 TLN2 AFDN DNAH5 IQGAP3 SDHA MGAM2

2.21e-0714251382130948266
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

SMG1 EPRS1 AHCYL1 HK2 MAGED1 MAN2B1 MINK1 FREM2 DST GTF3C1 WDR11 AFDN AKAP13 IQGAP3

3.47e-076501381438777146
Pubmed

A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins.

SMG1 AHCYL1 MAGED1 NDUFAF5 CENPB SYNE1 DENND4C ABHD4 LRIG3 ARFRP1 NDUFA12 ASAH1 TNRC6A AFDN

1.14e-067191381435337019
Pubmed

A high-throughput approach for measuring temporal changes in the interactome.

IPO5 KNTC1 USP34 EPRS1 AHCYL1 HK2 MAN2B1 WDR4 SWAP70 NPEPPS TOM1 NELFB FRYL OSGEP YWHAE PARP6 TKFC RAB3GAP2 EIF3K EIF2A

1.30e-0614551382022863883
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

EPRS1 TICRR FAT4 MYO7A NELFB MAGEE2 ITPR2 FREM2 DST MDN1 GTF3C1 PKD1 AKAP13 SDHA

1.50e-067361381429676528
Pubmed

In silico APC/C substrate discovery reveals cell cycle-dependent degradation of UHRF1 and other chromatin regulators.

IPO5 USP34 SMG1 EPRS1 AHCYL1 MAGED1 YWHAE KCTD17 GTF3C1 WDR11 TENM1 EIF3K ELAVL1 EIF2A IQGAP3 SDHA

1.68e-069711381633306668
Pubmed

The Notch ligands DLL1 and JAG2 act synergistically to regulate hair cell development in the mammalian inner ear.

MYO7A TECTA NOTCH1

3.37e-068138316141228
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

USP34 SMG1 SYNE1 TNRC6C DST RAB3GAP2 TLN2 CACNA1G

3.49e-06225138812168954
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

IPO5 EPRS1 AHCYL1 MYO7A NPEPPS SYNE1 MINK1 TOM1 YWHAE ITPR2 GJA3 DST NDUFA12 INF2 ELAVL1 TLN2 AFDN SDHA AGAP3

4.05e-0614311381937142655
Pubmed

Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.

IPO5 EPRS1 DYNC2H1 NPEPPS SYNE1 YWHAE GJA8 DST MDN1 AKAP9 ELAVL1 AKAP13 CACNA1G IQGAP3

4.35e-068071381430575818
Pubmed

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.

IPO5 KNTC1 USP34 SMG1 HK2 MAGED1 CENPB NPEPPS TOM1 YWHAE ITPR2 DST MDN1 GTF3C1 AARS2 INF2 EIF3K ELAVL1 SDHA

4.44e-0614401381930833792
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

KNTC1 ZNF473 SWAP70 DYNC2H1 COL27A1 NELFB GALNT16 FAN1 AARS2 WDR11 EEPD1

4.75e-064931381115368895
Pubmed

LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.

EPRS1 HK2 MAGED1 NUP107 DYNC2H1 TOM1 OSGEP NDUFA12 AARS2 INF2 PCSK6 RAB3GAP2 LSS IQGAP3 SDHA

5.46e-069421381531073040
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

EPRS1 AHCYL1 HK2 NUP107 DSG1 NPEPPS YWHAE TGM3 DST MDN1 GTF3C1 WDR11 INF2 SERPINB4 ELAVL1 AFDN AKAP13 EIF2A

7.24e-0613531381829467282
Pubmed

A High-Density Human Mitochondrial Proximity Interaction Network.

IPO5 HK2 NDUFAF5 NUP107 SYNE1 DPCD TNRC6C YWHAE ITPR2 DST MDN1 AKAP9 NDUFA12 AARS2 INF2 RAB3GAP2 FBXO7 ELAVL1 SDHA

7.63e-0614961381932877691
Pubmed

C9orf72 protein quality control by UBR5-mediated heterotypic ubiquitin chains.

IPO5 EPRS1 HK2 MAGED1 NUP107 DSG1 NPEPPS TOM1 OSGEP YWHAE MDN1 GTF3C1 WDR11 FBXO7 ELAVL1 IQGAP3 SDHA

1.07e-0512571381737317656
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

IPO5 USP34 NUP107 NPEPPS FRYL TGM3 DST MDN1 GTF3C1 ELAVL1 AFDN SDHA

1.23e-056531381222586326
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

USP34 FAT4 NUP107 MINK1 NELFB PPL LRIG3 ARFRP1 DST WDR11 TNRC6A AFDN AGAP3

1.42e-057771381335844135
Pubmed

Knock-in of alpha3 connexin prevents severe cataracts caused by an alpha8 point mutation.

GJA3 GJA8

1.56e-052138216687738
Pubmed

Cx46 hemichannels contribute to the sodium leak conductance in lens fiber cells.

GJA3 GJA8

1.56e-052138224380846
Pubmed

A hexokinase isoenzyme switch in human liver cancer cells promotes lipogenesis and enhances innate immunity.

HK2 GCK

1.56e-052138233594203
Pubmed

MYC-targeted WDR4 promotes proliferation, metastasis, and sorafenib resistance by inducing CCNB1 translation in hepatocellular carcinoma.

WDR4 EIF2A

1.56e-052138234244479
Pubmed

Absence of alpha3 (Cx46) and alpha8 (Cx50) connexins leads to cataracts by affecting lens inner fiber cells.

GJA3 GJA8

1.56e-052138216696970
Pubmed

Connexin 50 Regulates Surface Ball-and-Socket Structures and Fiber Cell Organization.

GJA3 GJA8

1.56e-052138227281269
Pubmed

Connections between connexins, calcium, and cataracts in the lens.

GJA3 GJA8

1.56e-052138215452195
Pubmed

Gap junctional coupling in lenses lacking alpha3 connexin.

GJA3 GJA8

1.56e-05213829860964
Pubmed

Unique and redundant connexin contributions to lens development.

GJA3 GJA8

1.56e-052138211786642
Pubmed

Identification and preliminary functional analysis of two novel congenital cataract associated mutations of Cx46 and Cx50.

GJA3 GJA8

1.56e-052138231618082
Pubmed

Structural and immunocytochemical alterations in eye lens fiber cells from Cx46 and Cx50 knockout mice.

GJA3 GJA8

1.56e-052138216740340
Pubmed

FBXO7, a tumor suppressor in endometrial carcinoma, suppresses INF2-associated mitochondrial division.

INF2 FBXO7

1.56e-052138237344480
Pubmed

Complementary expression and phosphorylation of Cx46 and Cx50 during development and following gene deletion in mouse and in normal and orchitic mink testes.

GJA3 GJA8

1.56e-052138226017495
Pubmed

Defining a link between gap junction communication, proteolysis, and cataract formation.

GJA3 GJA8

1.56e-052138211395508
Pubmed

Cataracts and microphthalmia caused by a Gja8 mutation in extracellular loop 2.

GJA3 GJA8

1.56e-052138223300808
Pubmed

Aging-dependent loss of GAP junction proteins Cx46 and Cx50 in the fiber cells of human and mouse lenses accounts for the diminished coupling conductance.

GJA3 GJA8

1.56e-052138234226295
Pubmed

Transglutaminase 3 Promotes Skin Inflammation in Atopic Dermatitis by Activating Monocyte-Derived Dendritic Cells via DC-SIGN.

CD209 TGM3

1.56e-052138231425706
Pubmed

A novel human Ada2 homologue functions with Gcn5 or Brg1 to coactivate transcription.

TADA2B TADA2A

1.56e-052138212972612
Pubmed

Calcium-Activated Chloride Channels in Newly Differentiating Mouse Lens Fiber Cells and Their Role in Volume Regulation.

GJA3 GJA8

1.56e-052138230995319
Pubmed

Dominant cataracts result from incongruous mixing of wild-type lens connexins.

GJA3 GJA8

1.56e-052138212782682
Pubmed

Functional effects of Cx50 mutations associated with congenital cataracts.

GJA3 GJA8

1.56e-052138224005045
Pubmed

Levels and Modifications of Both Lens Fiber Cell Connexins Are Affected in Connexin Mutant Mice.

GJA3 GJA8

1.56e-052138236139360
Pubmed

Do Connexin Mutants Cause Cataracts by Perturbing Glutathione Levels and Redox Metabolism in the Lens?

GJA3 GJA8

1.56e-052138233036381
Pubmed

A Gja8 (Cx50) point mutation causes an alteration of alpha 3 connexin (Cx46) in semi-dominant cataracts of Lop10 mice.

GJA3 GJA8

1.56e-052138211875045
Pubmed

Connexin46fs380 causes progressive cataracts.

GJA3 GJA8

1.56e-052138225103261
Pubmed

Connexin 50-R205G Mutation Perturbs Lens Epithelial Cell Proliferation and Differentiation.

GJA3 GJA8

1.56e-052138232182330
Pubmed

Gap junction communication influences intercellular protein distribution in the lens.

GJA3 GJA8

1.56e-052138218462719
Pubmed

Structure of native lens connexin 46/50 intercellular channels by cryo-EM.

GJA3 GJA8

1.56e-052138230542154
Pubmed

Properties of connexin 46 hemichannels in dissociated lens fiber cells.

GJA3 GJA8

1.56e-052138220861491
Pubmed

Notch1 Regulates Hippocampal Plasticity Through Interaction with the Reelin Pathway, Glutamatergic Transmission and CREB Signaling.

RELN NOTCH1

1.56e-052138226635527
Pubmed

Mutation analysis in Chinese families with autosomal dominant hereditary cataracts.

GJA3 GJA8

1.56e-052138225549162
Pubmed

AIMP2-DX2 provides therapeutic interface to control KRAS-driven tumorigenesis.

IPO5 EPRS1 DSG1 NPEPPS YWHAE ELAVL1 SDHA

1.61e-05200138735546148
Pubmed

FGFR2 is associated with hair thickness in Asian populations.

MSX2 TGM3 NOTCH1

1.70e-0513138319590514
Pubmed

LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.

IPO5 KNTC1 EPRS1 NUP107 FRYL AKAP13 IQGAP3

1.71e-05202138733005030
Pubmed

Proteomic analysis and identification of cellular interactors of the giant ubiquitin ligase HERC2.

ITPR2 AKAP9 ASAH1 ETAA1 EIF3K AGAP3

2.04e-05139138625476789
Pubmed

Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.

USP34 AHCYL1 MAGED1 B4GAT1 DYNC2H1 NPEPPS SLC7A6 LRIG3 TKFC MDN1 NDUFA12 SLC35F6 LSS EIF2A NOTCH1

2.21e-0510611381533845483
Pubmed

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.

GPLD1 FAT4 MAN2B1 B4GAT1 NPEPPS TOM1 SI YWHAE LRG1 FREM2 TKFC ASAH1 SMPDL3A CSPG4 CLEC3B

2.44e-0510701381523533145
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

AHCYL1 MAGED1 NUP107 DYNC2H1 SYNE1 MINK1 ITPR2 MDN1 AKAP9 NDUFA12 WDR11 INF2 RAB3GAP2 COL14A1 AKAP13 LSS EIF2A SDHA

2.56e-0514871381833957083
Pubmed

BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.

IPO5 EPRS1 AHCYL1 MINK1 YWHAE DENND4C DST RAB3GAP2 AFDN EIF2A NOTCH1 SDHA

2.72e-057081381239231216
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

MAGED1 SYNE1 MINK1 TOM1 YWHAE DST MDN1 NDUFA12 WDR11 TADA2B TNRC6A SLC35F6 EIF3K AFDN EIF2A IQGAP3 SDHA AGAP3

2.79e-0514971381831527615
Pubmed

Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia.

IPO5 SYNE1 FRYL YWHAE DST AKAP9

3.25e-05151138617043677
Pubmed

Asymmetric activation of Dll4-Notch signaling by Foxn4 and proneural factors activates BMP/TGFβ signaling to specify V2b interneurons in the spinal cord.

FOXN4 MSX2 NOTCH1

3.99e-0517138324257627
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

MINK1 NELFB FRYL YWHAE DENND4C DST MDN1 AKAP9 MTUS1 RAB3GAP2 AFDN AKAP13 AGAP3

4.12e-058611381336931259
Pubmed

Charged multivesicular body protein 4b forms complexes with gap junction proteins during lens fiber cell differentiation.

GJA3 GJA8

4.68e-053138236880430
Pubmed

[Evaluation of Gene Expression of Hexokinases in Colorectal Cancer with the Use of Bioinformatics Methods].

HK2 HK3

4.68e-053138226855992
Pubmed

Diverse gap junctions modulate distinct mechanisms for fiber cell formation during lens development and cataractogenesis.

GJA3 GJA8

4.68e-053138216611690
Pubmed

Reelin and Notch1 cooperate in the development of the dentate gyrus.

RELN NOTCH1

4.68e-053138219571148
Pubmed

Oncogenic circTICRR suppresses autophagy via binding to HuR protein and stabilizing GLUD1 mRNA in cervical cancer.

TICRR ELAVL1

4.68e-053138235595754
Pubmed

Lens Connexin Channels Show Differential Permeability to Signaling Molecules.

GJA3 GJA8

4.68e-053138232971763
Pubmed

Genetic variations in GJA3, GJA8, LIM2, and age-related cataract in the Chinese population: a mutation screening study.

GJA3 GJA8

4.68e-053138221386927
Pubmed

Analysis of Polymorphisms in Genes Differentially Expressed in the Enamel of Mice with Different Genetic Susceptibilities to Dental Fluorosis.

MMP20 COL14A1

4.68e-053138230149392
Pubmed

Expression of TNRC6 (GW182) Proteins Is Not Necessary for Gene Silencing by Fully Complementary RNA Duplexes.

TNRC6C TNRC6A

4.68e-053138231670606
Pubmed

Assembly of connexins and MP26 in lens fiber plasma membranes studied by SDS-fracture immunolabeling.

GJA3 GJA8

4.68e-05313829664032
Pubmed

Notch signaling pathway enhances bone morphogenetic protein 2 (BMP2) responsiveness of Msx2 gene to induce osteogenic differentiation and mineralization of vascular smooth muscle cells.

MSX2 NOTCH1

4.68e-053138221471203
Pubmed

Genetic interplays between Msx2 and Foxn1 are required for Notch1 expression and hair shaft differentiation.

MSX2 NOTCH1

4.68e-053138219103190
Pubmed

Charged Residues at the First Transmembrane Region Contribute to the Voltage Dependence of the Slow Gate of Connexins.

GJA3 GJA8

4.68e-053138227143357
Pubmed

Reelin induces a radial glial phenotype in human neural progenitor cells by activation of Notch-1.

RELN NOTCH1

4.68e-053138218593473
Pubmed

Impact of scaffolding protein TNRC6 paralogs on gene expression and splicing.

TNRC6C TNRC6A

4.68e-053138234108231
Pubmed

Reelin regulates differentiation of neural stem cells by activation of notch signaling through Disabled-1 tyrosine phosphorylation.

RELN NOTCH1

4.68e-053138222394407
Pubmed

Gawky is a component of cytoplasmic mRNA processing bodies required for early Drosophila development.

TNRC6C TNRC6A

4.68e-053138216880270
Pubmed

Differential genetic diagnoses of adult post-lingual hearing loss according to the audiogram pattern and novel candidate gene evaluation.

MYO7A NOTCH1

4.68e-053138234519870
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

USP34 NUP107 DENND4C DST GTF3C1 RAB3GAP2 TNRC6A TADA2A KAT14

4.70e-05418138934709266
Pubmed

The Catalytically Inactive Mutation of the Ubiquitin-Conjugating Enzyme CDC34 Affects its Stability and Cell Proliferation.

EPRS1 NUP107 NPEPPS MDN1 GTF3C1 AARS2 SDHA

4.75e-05237138729564676
Pubmed

Defining the human deubiquitinating enzyme interaction landscape.

IPO5 AHCYL1 CENPB DSG1 FBXW9 OTUD5 DYNC2H1 NPEPPS YWHAE TGM3 SERPINB4 TADA2B FBXO7 EIF3K

4.93e-0510051381419615732
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

EPRS1 AHCYL1 HK2 MAGED1 DSG1 MINK1 YWHAE NDUFA12 RAB3GAP2 TNRC6A TENM1 TLN2 AFDN SDHA AGAP3

4.96e-0511391381536417873
Pubmed

Global genetic analysis in mice unveils central role for cilia in congenital heart disease.

DYNC2H1 FREM2 PCSK6 PKD1 DNAH5

5.09e-05100138525807483
Pubmed

Large-scale mapping of human protein-protein interactions by mass spectrometry.

KNTC1 EPRS1 MAGED1 DSG1 NPEPPS DPCD NELFB FRYL OSGEP SERPINB4 RAB3GAP2 EIF3K PINX1 AFDN AKAP13 CLEC3B

5.30e-0512841381617353931
Pubmed

Tumor suppressor BAP1 nuclear import is governed by transportin-1.

IPO5 EPRS1 MAGED1 NPEPPS TOM1 YWHAE DST MDN1 GTF3C1 RAB3GAP2 EIF3K ELAVL1 AFDN EIF2A IQGAP3

5.47e-0511491381535446349
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

IPO5 EPRS1 NUP107 DSG1 NPEPPS SYNE1 YWHAE ITPR2 DST MDN1 GTF3C1 AARS2 ELAVL1 AFDN

6.03e-0510241381424711643
Pubmed

Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS.

USP34 AHCYL1 MAGED1 NPEPPS OSGEP YWHAE DST AKAP9 ELAVL1

6.05e-05432138923455922
Pubmed

QKI is a critical pre-mRNA alternative splicing regulator of cardiac myofibrillogenesis and contractile function.

DST AKAP9 CACNA1G

6.63e-0520138333397958
Pubmed

A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.

IPO5 NUP107 NPEPPS NELFB AARS2 WDR11 RAB3GAP2 AFDN LSS SDHA

8.48e-055601381035241646
Pubmed

Direct neuronal glucose uptake heralds activity-dependent increases in cerebral metabolism.

HK2 HK3

9.33e-054138225904018
Pubmed

Structural changes in lenses of mice lacking the gap junction protein connexin43.

GJA3 GJA8

9.33e-05413829620080
Pubmed

Lens connexins alpha3Cx46 and alpha8Cx50 interact with zonula occludens protein-1 (ZO-1).

GJA3 GJA8

9.33e-054138212808044
Pubmed

The interactions of GW182 proteins with PABP and deadenylases are required for both translational repression and degradation of miRNA targets.

TNRC6C TNRC6A

9.33e-054138223172285
Pubmed

Necdin interacts with the Msx2 homeodomain protein via MAGE-D1 to promote myogenic differentiation of C2C12 cells.

MAGED1 MSX2

9.33e-054138215272023
Pubmed

Two PABPC1-binding sites in GW182 proteins promote miRNA-mediated gene silencing.

TNRC6C TNRC6A

9.33e-054138221063388
Pubmed

Structural basis of binding of P-body-associated proteins GW182 and ataxin-2 by the Mlle domain of poly(A)-binding protein.

TNRC6C TNRC6A

9.33e-054138220181956
InteractionB4GALT2 interactions

USP34 FAT4 MAGED1 MTUS1 WDR11 EIF2A IQGAP3 SENP5

1.55e-061191378int:B4GALT2
InteractionRWDD4 interactions

KCTD17 FCGRT FBXO7 ELAVL1

1.36e-05221374int:RWDD4
InteractionRYK interactions

FAT4 NPEPPS OSGEP SLC7A6 FREM2 DST CSPG4 ELAVL1 AFDN

1.49e-052121379int:RYK
GeneFamilyZinc fingers MYND-type|A-kinase anchoring proteins

MYO7A AKAP9 AKAP13

4.51e-0429943396
GeneFamilyEF-hand domain containing|Plakins

PPL DST

7.34e-048942939
GeneFamilyHelix-turn-helix CENPB type domain containing

CENPB TIGD2

2.01e-0313942533
GeneFamilyATAC complex

TADA2A KAT14

2.01e-03139421058
GeneFamilyGATA zinc finger domain containing|Myb/SANT domain containing

MIER3 TADA2B TADA2A

2.64e-0353943532
GeneFamilyCadherin related

FAT4 CDHR3

3.46e-031794224
GeneFamilyX-linked mental retardation|Rho GTPase activating proteins|BAR-PH domain containing

AGAP11 AGAP3

3.46e-03179421291
GeneFamilyAminoacyl tRNA synthetases, Class II

EPRS1 AARS2

4.32e-0319942132
CoexpressionHE_LIM_SUN_FETAL_LUNG_C2_APOE_POS_M2_MACROPHAGE_CELL

HK3 CENPB MYO7A IFIT2 DENND4C CD209 DST INF2 SMPDL3A EEPD1 RAB3GAP2 SLC35F6 AGAP3 SENP5

2.38e-0747613814M45717
ToppCell10x5'v1-week_17-19-Myeloid_macrophage|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

MYO7A COL27A1 CD209 LIPA MTUS1 FCGRT ASAH1 SMPDL3A CSPG4

1.27e-081991389980b10b81ee9dc952e3be25bd294201ce5a4ca8b
ToppCell10x5'v1-week_17-19-Myeloid_macrophage-stroma|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

MYO7A COL27A1 CD209 LIPA MTUS1 FCGRT ASAH1 SMPDL3A CSPG4

1.27e-081991389cbd423c31d75f6d2f5ae85d2241641fcbe630b81
ToppCell3'_v3-GI_small-bowel-Myeloid_Mac|GI_small-bowel / Manually curated celltypes from each tissue

MAN2B1 LRG1 CD209 LIPA DST FCGRT SMPDL3A EEPD1

2.06e-0719913888990a3d69e24cb3aaba9d6def3d0be9ee973436d
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX11 FAT4 RELN FREM2 TENM1 TLN2 DNAH5

1.76e-0618413872cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX11 FAT4 RELN FREM2 TENM1 TLN2 DNAH5

1.76e-061841387ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX11 FAT4 RELN FREM2 TENM1 TLN2 DNAH5

1.76e-0618413872b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellfacs-Tongue-nan-3m-Epithelial-keratinocyte|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HK2 PPL TGM3 AFDN AKAP13 LSS PLA2G4F

2.42e-06193138733437fdb417d78463caee14a9f0e094da1733829
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.3|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DYNC2H1 SYNE1 CDHR3 FREM2 MTUS1 PLA2G4F DNAH5

2.42e-061931387bdb7401dd9059032f930f2b575f2ef8e504b6594
ToppCellLPS-IL1RA-Unknown-Endothelial-Pericyte_2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

RELN GJA8 CSPG4 PKD1 WDR17 EBF4

2.60e-0612513862938a1d62afe1e0a3abba5eb92f07b886cc0accd
ToppCell10x5'v1-week_17-19-Myeloid_macrophage-stroma-stromal_macrophage|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

MYO7A CD209 LIPA MTUS1 FCGRT ASAH1 SMPDL3A

2.96e-0619913872649afa3ccda78e9d1df26127b66cbfa0c6cd01d
ToppCell3'_v3-GI_small-bowel-Myeloid_Mac-Intestinal_macrophages|GI_small-bowel / Manually curated celltypes from each tissue

LRG1 CD209 LIPA DST FCGRT SMPDL3A EEPD1

2.96e-06199138796070b5ffcbab4952970f43b536969ddd2ca5d14
ToppCell10x5'v1-week_14-16-Myeloid_macrophage-stroma-stromal_macrophage|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

MYO7A CD209 LIPA FCGRT ASAH1 SMPDL3A AGAP3

3.06e-062001387af743dfef7e7cfaef1c494999757123f93a213e3
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligoastrocytoma|TCGA-Brain / Sample_Type by Project: Shred V9

TNRC6C DST MDN1 NALCN EEPD1 PPM1L

1.11e-051611386347edb0de10850b7d16c40945751033289289c9b
ToppCelldroplet-Marrow-nan-24m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MINK1 LIPA FCGRT SMPDL3A INPP5J PSD4

1.42e-051681386e979a4fbeb9f21048b47d69e6da75c57650697f2
ToppCellfacs-Lung-Endomucin-3m-Endothelial-Lymphatic_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AHCYL1 RELN MYO7A DPCD KCTD17 PCSK6

1.62e-051721386b3c4adccc34bb9e4e78e40f4e2e23736c347cc75
ToppCellfacs-Lung-Endomucin-3m-Endothelial-endothelial_cell_of_lymphatic_vessel|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AHCYL1 RELN MYO7A DPCD KCTD17 PCSK6

1.62e-0517213862f1673fcb2356684d60871debb0f159aec553a1c
ToppCellfacs-Lung-Endomucin-24m-Endothelial-endothelial_cell_of_lymphatic_vessel|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN MYO7A LRG1 KCTD17 FCGRT PCSK6

1.84e-051761386057d2759fdc67176c25802b57a78064d8cc93205
ToppCellfacs-Lung-Endomucin-24m-Endothelial-Lymphatic_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN MYO7A LRG1 KCTD17 FCGRT PCSK6

1.84e-051761386b81e5d23b31cefc8d374ef403e21acc390c14a80
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma|TCGA-Brain / Sample_Type by Project: Shred V9

SYNE1 TNRC6C DST MDN1 NALCN PPM1L

1.90e-051771386e8ab340b20cd41554c3841fe980e078e878af35f
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DYNC2H1 CDHR3 AGAP11 GLB1L2 AFDN DNAH5

2.09e-05180138692fb01b91261b3103454924cde56add337b41844
ToppCellBAL-Severe-Myeloid-Macrophage|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SWAP70 LIPA DST FCGRT SLC35F6 CLEC3B

2.44e-051851386ae966929fb5bbb08ffcbac76cb21941638727f55
ToppCellBAL-Severe-Myeloid-Macrophage-transitional_Macro-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

SWAP70 LIPA DST FCGRT SLC35F6 CLEC3B

2.44e-0518513863beebaa92275086b1fae5f8c0c3d54016c5ba2aa
ToppCellBAL-Severe-Myeloid-Macrophage-transitional_Macro-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SWAP70 LIPA DST FCGRT SLC35F6 CLEC3B

2.44e-051851386ceff11cfa679147ccfd0a0f8079e697a6bea34d9
ToppCellBAL-Severe-Myeloid-Macrophage|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

SWAP70 LIPA DST FCGRT SLC35F6 CLEC3B

2.44e-0518513869aea5ed8f9cee5ee933891203aac7adb85d68201
ToppCellBAL-Severe-Myeloid-Macrophage-transitional_Macro|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

SWAP70 LIPA DST FCGRT SLC35F6 CLEC3B

2.44e-05185138642939b294ea3e871274d8b73124c850dc1904fd2
ToppCellSevere_COVID-19-Myeloid-transitional_Macro|Severe_COVID-19 / Disease group,lineage and cell class (2021.01.30)

SWAP70 LIPA DST FCGRT SLC35F6 CLEC3B

2.44e-051851386f7ef0d7740b4cfedc38846e802898c402dc411fd
ToppCellBAL-Severe-Myeloid-Macrophage-transitional_Macro|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SWAP70 LIPA DST FCGRT SLC35F6 CLEC3B

2.44e-0518513867a3612520ae4f0cd61480eadba31eecce001419d
ToppCellnormal_Lymph_Node-Myeloid_cells-mo-Mac|normal_Lymph_Node / Location, Cell class and cell subclass

HK3 CD209 LIPA DST FCGRT SMPDL3A

2.67e-051881386e83de94a9b47a6a90e98face887eae031a322af6
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-Mono-Mono_anti-infl-D|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MAN2B1 CD209 LIPA FCGRT ASAH1 SMPDL3A

2.67e-0518813865f6ad5d693145d846ca561c2fa55465a88e40b90
ToppCellfacs-Lung-3m-Endothelial-lymphatic_endothelial|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RELN MYO7A LRG1 KCTD17 FCGRT PCSK6

2.84e-051901386a1514d2186eb4fe569971ab22dc0c17d353fb94a
ToppCellfacs-Lung-3m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RELN MYO7A LRG1 KCTD17 FCGRT PCSK6

2.84e-0519013860bb954a94317cfc742b9b6221bb80f8baa6d3ff1
ToppCellfacs-Lung-3m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RELN MYO7A LRG1 KCTD17 FCGRT PCSK6

2.84e-05190138626e2237f65cb43723c5da853831b40df2982d6e4
ToppCelldroplet-Tongue-nan-3m-Epithelial-suprabasal_interpapillary|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NPEPPS PPL ITPR2 TGM3 AFDN PLA2G4F

2.92e-051911386abdd93b2313e635f75a750d051a6a01ddc4e2df9
ToppCellCiliated-cil-3|World / Class top

DYNC2H1 SYNE1 CDHR3 COL27A1 DPCD DNAH5

3.01e-0519213864989ebb8812b8af1870599acd932849122c05a29
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

FREM2 MTUS1 LSS PLA2G4F DNAH5 MUCL3

3.01e-051921386cc9911e182a289779a2612bc213daae5607689e7
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2-D122|Adult / Lineage, Cell type, age group and donor

FREM2 MTUS1 LSS PLA2G4F DNAH5 MUCL3

3.01e-05192138606013a07e3a873b1d1c0451643c528593ac32a9c
ToppCellTCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6|TCGA-Prostate / Sample_Type by Project: Shred V9

USP34 EPRS1 FRYL DENND4C AKAP9 WDFY1

3.10e-051931386abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_I-E|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MAN2B1 ITPR2 LIPA FCGRT ASAH1 TLN2

3.10e-051931386697518bab1338dc441b2d93b410d957e692f20e6
ToppCellhuman_hepatoblastoma-Tumor_cells|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)

COL27A1 GPC6 ITPR2 PCSK6 TNRC6A AFDN

3.10e-051931386503a979328c68b096680b71359a26f02fafdff35
ToppCell5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.1.3|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MTUS1 AKAP13 LSS PLA2G4F HYI MUCL3

3.10e-051931386ba484fa1f290a92ae02475a4c468b4ac840c133e
ToppCellPBMC-Mild-Myeloid-Neutrophil-Neutrophil-Neu_1|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

FOXN4 IFIT2 LRG1 TGM3 CSPG4

3.21e-051171385089793a950e8593b4acc1ba6a5e5474682f5fda6
ToppCellPBMC-Mild-Myeloid-Neutrophil-Neutrophil-Neu_1|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

FOXN4 IFIT2 LRG1 TGM3 CSPG4

3.21e-0511713853d98d77b4725d684e7496059e8b0ffffbe40301d
ToppCellBronchial-NucSeq-Immune_Lymphocytic-B-B_plasma-B_plasmablast|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TICRR MAN2B1 MYO7A NAGPA IQGAP3 SDHA

3.28e-051951386a045fb8a377e54fb57fef1181d4c3fc15d627ef6
ToppCelldroplet-Tongue-TONGUE-1m-Epithelial-keratinocyte|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TOM1 PPL ITPR2 TGM3 PLA2G4F WDFY1

3.28e-051951386c54b19e31efe2c9ae690062569da7c0f1120a1d8
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN MAGED1 DYNC2H1 FRYL DST AKAP9

3.28e-0519513863e519cffa6144a62b06124642a14c9ff39b76554
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN MAGED1 DYNC2H1 FRYL DST AKAP9

3.28e-0519513867796ea9247f4c63762f0de8490fed08b9717fa23
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SYNE1 FREM2 MTUS1 AKAP13 PLA2G4F MUCL3

3.38e-0519613867e5addaa844e66f8160e05858c341866a80aed23
ToppCell10x3'2.3-week_14-16-Myeloid_macrophage-stroma|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

COL27A1 CD209 LIPA FCGRT ASAH1 EEPD1

3.38e-051961386bd2c2de103e28b65ea537c22f71225cb0deef1e0
ToppCell10x3'2.3-week_14-16-Myeloid_macrophage|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

COL27A1 CD209 LIPA FCGRT ASAH1 EEPD1

3.38e-051961386072a4150ae521c6589b0f7cd60e975fb33715bf4
ToppCell10x3'2.3-week_17-19-Myeloid_macrophage-stroma-stromal_macrophage|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

MYO7A CD209 LIPA FCGRT ASAH1 SMPDL3A

3.38e-05196138688517bb92be2f05c1e1ad94af22ac10d8c5c13c7
ToppCellsevere-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

USP34 SMG1 SYNE1 FRYL AKAP9 TENM1

3.47e-05197138657ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCell10x5'v1-week_12-13-Myeloid_macrophage-stroma-stromal_macrophage|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

CD209 ITPR2 LIPA MTUS1 FCGRT ASAH1

3.47e-051971386075044c17f1c52008cd3c292c15cbf485b50411e
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FAT4 SYNE1 COL27A1 SLC7A6 GALNT16 MDN1

3.57e-051981386a860246bcea847249a78fd2e86ed8e04371060db
ToppCellmild-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

USP34 SMG1 SYNE1 FRYL AKAP9 TENM1

3.67e-051991386f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCellBAL-Control-cDC_0|Control / Compartment, Disease Groups and Clusters

HK3 MINK1 CD209 LIPA FCGRT ASAH1

3.67e-0519913864518ffa51ead9da1ddf07bf048b18602e50f0f84
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-Mono-Mono_anti-infl-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

HK3 CD209 FCGRT ASAH1 SMPDL3A AKAP13

3.67e-051991386667b8b47a5b388506e3177b46747267fad8024f6
ToppCell5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SYNE1 FREM2 MTUS1 AKAP13 LSS PLA2G4F

3.67e-0519913862dc33804f6691d7c9682e6c9b885e945fb97fc36
ToppCellLPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

DYNC2H1 SYNE1 DST AKAP9 GTF3C1 COL14A1

3.78e-0520013869b0916d8d07ac2bf1739f7be5296bf77ffee6094
ToppCellLPS_IL1RA-Endothelial-Endothelial-Gen_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

USP34 FAT4 DST PINX1 AFDN NOTCH1

3.78e-052001386dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCellMild-Myeloid-Macrophages-FCN1-SPP1+|Mild / Condition, Lineage, Cell class and cell subclass

SWAP70 LIPA FCGRT ASAH1 SMPDL3A EEPD1

3.78e-052001386e5afd8e2cb2c63899d49fe17011f474d20bb06ea
ToppCellSevere_COVID-19-Myeloid-MoAM4|Severe_COVID-19 / Disease group,lineage and cell class (2021.01.30)

CD209 LIPA FCGRT SMPDL3A EEPD1 AGAP3

3.78e-05200138630448a41ca64d6f0fedaff0b7a6670dd33cdf2c5
ToppCellBAL-Severe-Myeloid-MoAM-MoAM4-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CD209 LIPA FCGRT SMPDL3A EEPD1 AGAP3

3.78e-0520013864f481d87e30195365900acb5d50641a9e7b2f462
ToppCellBAL-Severe-Myeloid-MoAM-MoAM4-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

CD209 LIPA FCGRT SMPDL3A EEPD1 AGAP3

3.78e-0520013865490393c5f54748f912676e19b58bd1320415a06
ToppCellBAL-Severe-Myeloid-MoAM-MoAM4|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CD209 LIPA FCGRT SMPDL3A EEPD1 AGAP3

3.78e-052001386cf720d3973e79ffd4c6e763a7284799ced22a274
ToppCellBAL-Severe-Myeloid-MoAM-MoAM4|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

CD209 LIPA FCGRT SMPDL3A EEPD1 AGAP3

3.78e-052001386df821ac12953e44fcfedbbefb35a4976e406ccd6
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW23-Neuronal-GABAergic_neurons|GW23 / Sample Type, Dataset, Time_group, and Cell type.

SOX11 RELN DST AKAP9 MTUS1 AFDN

3.78e-052001386c6bbd33bca86ac7a76a7ba704b3e141237d04549
ToppCellHippocampus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a6-Excitatory_Neuron.Slc17a6.Htr1a_(Neuron.Slc17a6.Htr1a)-|Hippocampus / BrainAtlas - Mouse McCarroll V32

GALR1 GABRQ PPL TGM3

5.59e-05671384be6853b5bf254063f02a4c478fd4c3fef68cb77a
ToppCellHippocampus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a6-Excitatory_Neuron.Slc17a6.Htr1a_(Neuron.Slc17a6.Htr1a)|Hippocampus / BrainAtlas - Mouse McCarroll V32

GALR1 GABRQ PPL TGM3

5.59e-056713847483b85423d9d07b01b60927d0fe1b7ccb241d7f
ToppCellTCGA-Peripheral_Nervous_System-Primary_Tumor-Paraganglioma-Paraganglioma-3|TCGA-Peripheral_Nervous_System / Sample_Type by Project: Shred V9

DYNC2H1 SYNE1 TECTA AFDN WDR17

6.36e-051351385ac20133d4a36f48338b45bffb13e842cb66f83ad
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GABRQ GPC6 TENM1 COL14A1 PSD4

8.35e-0514313857a7a9829ba63468c9745904d9e993590051207ab
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

GPLD1 ABHD4 LRIG3 MTUS1 DNAH5

1.37e-0415913858680b054622f573a82b1625fb93c2d5db81d1034
ToppCelldroplet-Lung-nan-3m-Myeloid-Proliferating_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KNTC1 TICRR NUP107 SLC7A6 AARS2

1.41e-0416013858a7a73b0ee1877fe02d47f745d36ae2858b529e1
ToppCellAdult-Mesenchymal-myofibroblast_cell-D175|Adult / Lineage, Cell type, age group and donor

GPC6 NALCN TENM1 PINX1 COL14A1

1.46e-041611385048b7dc00746987a24bf870d4d278c4183eb04a2
ToppCellfacs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TECTA TGM3 FREM2 TENM1 CES4A

1.50e-041621385bf886e22ff2a20353499004b53f25fb9e6574896
ToppCellfacs-Marrow-T-cells-24m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HK3 SYNE1 LRG1 IQGAP3 INPP5J

1.59e-0416413852a230ea066decb798a0e6f2b96c7608c8e608031
ToppCellfacs-Marrow-T-cells-24m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HK3 SYNE1 LRG1 IQGAP3 INPP5J

1.59e-041641385d02d39edd0bfef5a53b814ec6d5f026d41253218
ToppCellfacs-Large_Intestine-Distal-3m-Epithelial-enterocyte_of_epithelium_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HK2 TGM3 INF2 AKAP13 PLA2G4F

1.78e-04168138503896466698a79f7f1ad862cb7e05585260e2a5a
ToppCelldroplet-Marrow-BM-1m-Myeloid-monocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAN2B1 LIPA FCGRT ASAH1 SMPDL3A

1.83e-0416913858066b4c02c97d00034802cff2b39799ef44cc904
ToppCelldroplet-Marrow-nan-3m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IFIT2 GTF3C1 WDR11 LSS CACNA1G

1.83e-0416913855f5bec13208f4c3b6eacbba180c8a6402743b76e
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GPC6 GALNT16 FREM2 COL14A1 WDR17

1.93e-0417113854ede831aed364cb5271f49a8b09bb6d0452f9b35
ToppCellnormal_Lung-T/NK_cells-CD8+/CD4+_Mixed_Th|T/NK_cells / Location, Cell class and cell subclass

NUP107 TOM1 SLC7A6 MTUS1 INF2

1.98e-0417213850657c736f3c52d25cf7f652eac005ddcde9232ef
ToppCellfacs-Marrow-T_cells-18m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX11 HK3 SYNE1 LRG1 MTUS1

2.04e-0417313850f9784b30c81a4a4940e0623cec60d596e9985d2
ToppCellfacs-Marrow-T_cells-18m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX11 HK3 SYNE1 LRG1 MTUS1

2.04e-04173138560f79e0698a7cf7516690fb20f1b82ee46547699
ToppCellsaliva-Mild-Moderate_progression_d12-25-Myeloid-Macrophage-macrophage,_alveolar-Macro_c1-C1QC|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

MYO7A LIPA MDN1 PLA2G4F NOTCH1

2.09e-041741385d77fa525d5c87c190b4a10787b270eabd16c610f
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Myeloid-Monocytic-Nonclassical_Monocyte-Mono_c5-CD16|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

HK2 FCGRT ASAH1 CLEC3B AGAP3

2.15e-041751385dc7721794162dee96944f4b4b87b5681bb02ea8f
ToppCelldroplet-Liver-Npc-18m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HK2 MAN2B1 HK3 ASAH1 SMPDL3A

2.15e-0417513851973fff0d7e1a94b31f461a39b91cc7984ebd8f1
ToppCellPND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GCK GPC6 GALNT16 CSPG4 IQGAP3

2.20e-04176138575412d58438d71c49a6096bb2ef12b7f349653d8
ToppCelldroplet-Liver-Npc-18m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HK2 MAN2B1 HK3 ASAH1 SMPDL3A

2.20e-0417613851e430dffddd315d9a1cb4bd7fef5077656351c65
ToppCelldroplet-Tongue-nan-24m|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HK2 PPL TGM3 AFDN CLEC3B

2.20e-0417613859739b0653c511ab017507a0c7ee4f6d7082e87db
ToppCell356C-Myeloid-Macrophage-FABP4+_Macrophage_3|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

FAT4 COL27A1 GALNT16 PCSK6 COL14A1

2.26e-0417713853d955ea938a1d2fb1b6d68d4997fd454bd632dfc
ToppCellRV-11._Adipocyte|World / Chamber and Cluster_Paper

HK2 SLC7A6 ITPR2 EEPD1 TLN2

2.26e-041771385f0edf04930692418953e4f00a917257804ec0ffd
ToppCell10x3'2.3-week_17-19-Mesenchymal_osteo-stroma-chondrocyte|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

COL27A1 GPC6 LRIG3 CSPG4 COL14A1

2.26e-041771385915b848d789051a1c3bc6f6dc86955bb752276ab
ToppCelldroplet-Marrow-nan-21m-Myeloid-monocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAN2B1 LIPA FCGRT ASAH1 SMPDL3A

2.26e-041771385b860013f1fd397400a62d66ab521cfc81349ffe2
ToppCelldroplet-Tongue-nan-24m-Epithelial|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HK2 PPL TGM3 AFDN CLEC3B

2.32e-041781385a3176b2b335db22bb0fb71aafa5d7a287809396e
ToppCell10x5'v1-week_17-19-Myeloid_macrophage-stroma-monocytoid_macrophage|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

GALR1 CD209 FCGRT ASAH1 CACNA1G

2.45e-041801385ba4c1fb55e8f1095bea6968417fefcf5f700926b
ToppCellP28-Mesenchymal-mesenchymal_fibroblast-mesenchymal_alveolar_niche_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

GPLD1 HK2 GPC6 COL14A1 CLEC3B

2.45e-0418013859adebde5f4ca6dcb90e9113622862e14298465ac
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Epithelial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TICRR HK2 GPC6 MSX2 CLEC3B

2.57e-041821385904804813849b7f7f716ba1554d33b07bc0a701e
ToppCellwk_20-22-Mesenchymal-Chondrocyte-Resting_chondrocyte|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

COL27A1 MIER3 KCTD17 FAN1 CSPG4

2.57e-04182138503a5a02acd48f0eb210485348bfe0cd21f486215
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Epithelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TICRR HK2 GPC6 MSX2 CLEC3B

2.57e-0418213855d8b7fe18286e27f0f50c5d2d9be56850e2cb8f4
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Epithelial-Bergmann_glial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPLD1 HK2 GPC6 MSX2 CLEC3B

2.64e-04183138525c96df8ea0c7bbedbb7699ee84ad6234d19cba8
Druglofenal

HK2 HK3 GCK

8.30e-0741363CID000159256
DrugN-bromoacetylglucosamine

HK2 HK3 GCK

8.30e-0741363CID000152920
DrugAC1L5VHN

HK2 HK3 GCK

8.30e-0741363CID000235938
Drug2,3-anhydro-D-allose

HK2 HK3 GCK

8.30e-0741363CID000191595
Drug1,5-anhydroglucitol 6-phosphate

HK2 HK3 GCK

8.30e-0741363CID003081444
Drug1-deoxy-D-manno-heptulose

HK2 HK3 GCK

8.30e-0741363CID000193198
Drugtriethyltin bromide

HK2 HK3 GCK AKAP13

8.35e-07131364CID000017701
Drug3-chloromethylthiochromone-1,1-dioxide

HK2 HK3 GCK

2.07e-0651363CID000100620
Drug2-fluoro-2-deoxy-6-phosphogluconate

HK2 HK3 GCK

2.07e-0651363CID000127270
DrugTC-3

DSG1 SYNE1 GCK PPL PCSK6 CLEC3B

3.58e-06691366CID000398798
Drug8-thiocyano-ATP

HK2 HK3 GCK

4.12e-0661363CID000132196
DrugAC1L5A5F

HK2 HK3 GCK

7.17e-0671363CID000173497
Drugglucose 6-arsenate

HK2 HK3 GCK

7.17e-0671363CID000128033
DrugAFDG

HK2 HK3 GCK

1.14e-0581363CID000164297
Drugtetrahydropyran-2-methanol

HK2 HK3 GCK

1.14e-0581363CID000007524
DrugTetrandrine [518-34-3]; Up 200; 6.4uM; PC3; HT_HG-U133A

NDUFAF5 MINK1 PARP6 MTUS1 ETAA1 TENM1 COL14A1 AFDN

1.85e-0518913685821_UP
DrugATP-EDC

HK2 HK3 GCK

2.43e-05101363CID000195647
DrugRaloxifene hydrochloride [82640-04-8]; Down 200; 7.8uM; HL60; HT_HG-U133A

ZNF473 DYNC2H1 ITPR2 MTUS1 INF2 SLC35F6 AKAP13 TADA2A

2.49e-0519713682738_DN
Drug4,4'-thiodiphenol

GJA3 GJA8 LIPA DNAH5

3.85e-05321364CID000017570
Druglonidamine

HK2 HK3 TOM1 GCK

4.36e-05331364CID000039562
Diseasehyperinsulinemic hypoglycemia (implicated_via_orthology)

HK2 HK3 GCK

9.10e-0751343DOID:13317 (implicated_via_orthology)
DiseaseGalloway Mowat syndrome

WDR4 NUP107 OSGEP

5.04e-0681343C0795949
Diseasematurity-onset diabetes of the young (implicated_via_orthology)

HK2 HK3 GCK

1.07e-05101343DOID:0050524 (implicated_via_orthology)
Diseasehyperglycemia (implicated_via_orthology)

HK2 HK3 GCK

5.94e-05171343DOID:4195 (implicated_via_orthology)
DiseaseGalloway-Mowat syndrome (is_implicated_in)

WDR4 NUP107

2.03e-0451342DOID:0080694 (is_implicated_in)
Diseaseglucose metabolism disease (implicated_via_orthology)

HK2 HK3 GCK

2.76e-04281343DOID:4194 (implicated_via_orthology)
DiseaseChanarin-Dorfman syndrome (implicated_via_orthology)

PNPLA5 ABHD4

3.03e-0461342DOID:0050729 (implicated_via_orthology)
Diseaseobesity (implicated_via_orthology)

FAT4 GCK PNPLA5 ITPR2 ABHD4 NOTCH1

4.62e-042151346DOID:9970 (implicated_via_orthology)
Diseasecataract (implicated_via_orthology)

GJA3 GJA8 LSS

6.88e-04381343DOID:83 (implicated_via_orthology)
DiseaseCATARACT, COPPOCK-LIKE

GJA3 GJA8

7.22e-0491342C1852438
DiseaseCataract, Pulverulent

GJA3 GJA8

7.22e-0491342C1833118
Diseasecomplement C1q subcomponent subunit C measurement

IFIT2 LIPA

8.99e-04101342EFO_0801492
Diseasemyeloid white cell count

USP34 SWAP70 GALNT16 LIPA ARFRP1 GTF3C1 TADA2B PKD1 PINX1 CES4A TLN2 TADA2A

1.19e-0393713412EFO_0007988
DiseaseConnective Tissue Diseases

PKD1 NOTCH1

1.55e-03131342C0009782
Diseasepulse pressure measurement

USP34 SWAP70 DYNC2H1 COL27A1 FRYL GCK DENND4C LRIG3 ASAH1 EEPD1 PKD1 TNRC6A PINX1 TLN2 AKAP13

1.68e-03139213415EFO_0005763
DiseaseAlzheimer disease

RELN CDHR3 GPC6 NDUFA12 TNRC6A TLN2 CACNA1G CLEC3B

1.73e-034851348MONDO_0004975
Diseasealkaline phosphatase measurement

GPLD1 USP34 MINK1 GCK IFIT2 PPL LIPA FCGRT PKD1 PINX1 AKAP13 NOTCH1

2.33e-03101513412EFO_0004533
DiseaseCongenital total cataract

GJA8 LSS

2.36e-03161342C0266539
DiseaseNuclear non-senile cataract

GJA3 GJA8

2.99e-03181342C1112705
DiseaseNuclear cataract

GJA3 GJA8

2.99e-03181342C0392557
Diseasetuberculosis

DYNC2H1 GPC6 LIPA NALCN PCSK6

3.12e-032161345MONDO_0018076
Diseasesusceptibility to vaginal yeast infection measurement

DSG1 MTUS1 TLN2

3.26e-03651343EFO_0008412
DiseaseLipoidosis

ASAH1 LSS

3.33e-03191342C0023794
DiseaseHydrops Fetalis

LIPA ASAH1

3.33e-03191342C0020305
Diseaseprimary ciliary dyskinesia (implicated_via_orthology)

DPCD DNAH5

3.33e-03191342DOID:9562 (implicated_via_orthology)
Diseaseneuroimaging measurement

SOX11 RELN FRYL YWHAE DENND4C KCTD17 MSX2 RAB3GAP2 PKD1 TNRC6A TLN2 AGAP3

3.54e-03106913412EFO_0004346
Diseaseamino acid measurement

IPO5 SOX11 FAT4 SYNE1 MMP20 PCSK6 COL14A1 NOTCH1 MGAM2

3.88e-036781349EFO_0005134
Diseaseneutrophil count

DYNC2H1 YWHAE GALNT16 ITPR2 GJA8 LIPA ARFRP1 GTF3C1 DCUN1D2 TADA2B PKD1 TNRC6A TLN2 AKAP13

4.16e-03138213414EFO_0004833
DiseaseIntellectual Disability

WDR4 SYNE1 OSGEP ASAH1 LSS CACNA1G EIF2A

4.42e-034471347C3714756
Diseaseblood pressure

SYNE1 GPC6

4.46e-03221342EFO_0004325

Protein segments in the cluster

PeptideGeneStartEntry
DNLTLWTSDMQGDGE

YWHAE

226

P62258
GALAFWMANASELLN

AFDN

686

P55196
AMGNALANSVWEGAL

AGAP3

696

Q96P47
WGQQTDGMKLEFGEE

AKAP9

1281

Q99996
ASLGQPNWDMRDGFD

LRG1

281

P02750
MSSIGNDLANSIWEG

AGAP11

396

Q8TF27
FVATRQGESSGDMAW

CSPG4

986

Q6UVK1
REMLDQSNQWGGTAL

B4GAT1

241

O43505
DAQTAGFDGCIASMW

FAT4

4356

Q6V0I7
TGVGNDENMSNTWKF

AKAP13

1911

Q12802
MADDLEQQSQGWLSS

ABHD4

1

Q8TB40
NRFTWMGLSDLNQEG

CD209

311

Q9NNX6
MDFGVFLGWNINNDT

ASAH1

161

Q13510
WDAAAGMELRDAGSQ

EEPD1

356

Q7L9B9
DAQMDIWGGENFELS

GALNT16

311

Q8N428
FGNLSMVTNLDDSNW

NUP107

96

P57740
MCVNTEWGAFGDSGE

GCK

251

P35557
AMRVSLDAAGNEGSW

ITPR2

146

Q14571
TEMNGKNTFWDVDGS

NDUFA12

66

Q9UI09
KEEMQFAVGWSGSLN

RAB3GAP2

111

Q9H2M9
WDMAADGQQFGEIKA

FBXW9

251

Q5XUX1
EQMSALGESGWQEDI

MDN1

2831

Q9NU22
SDGALMDDNQNEWGD

NOTCH1

1801

P46531
FMNGNRASEAVLWEA

MAGED1

571

Q9Y5V3
AGLEFWSEDTMNDKA

MAGEE2

301

Q8TD90
GLWIDMNEPSNFVDG

MGAM2

1371

Q2M2H8
GSSFGLTWDANDMVI

MTUS1

406

Q9ULD2
DGAFWGLSNMEILQL

LRIG3

256

Q6UXM1
SVQDGLDEMLDWMGN

DST

4161

Q03001
STWGLNDDELMAHGQ

GABRQ

556

Q9UN88
KNSGQEASFMIWTGD

SMPDL3A

96

Q92484
LWLSDGSMGFGQESD

FREM2

2871

Q5SZK8
DTWNLLLDFGNMIAD

DCUN1D2

211

Q6PH85
CINMEWGAFGDDGSL

HK2

256

P52789
NGEEFMNFDLKQGTW

FCGRT

136

P55899
LDLSNEGFTNWEFMT

PCSK6

576

P29122
QKNNGESWELMDSAG

PPL

426

O60437
AWSNDDSKFGQRMLE

PINX1

21

Q96BK5
GDSLNSDEGDVSWME

KAT14

56

Q9H8E8
DDSHARGNWGLLDQM

CES4A

181

Q5XG92
EDAEGESMDNFNWGV

FRYL

2436

O94915
SRQMADGGWGEDFES

LSS

621

P48449
ALGQGAWDMIDSQVF

NELFB

346

Q8WX92
MWNDIELLTNDDTGS

KNTC1

1

P50748
LGQDADEGILWQMFG

ELAVL1

251

Q15717
NGKASQEGMTAWTEE

MIER3

271

Q7Z3K6
ADFAAGAMENWDLVT

NPEPPSL1

311

A6NEC2
MSDDDGWEFVNLGDQ

IPO5

651

O00410
LQGMWGSAFATSLDE

PLA2G4F

556

Q68DD2
FCIDNGAMIAQAGWE

OSGEP

291

Q9NPF4
INMEWGAFGDDGSLA

HK3

711

P52790
MSDGWRFEQLVNIGS

KCTD17

161

Q8N5Z5
SGNEGNWFEIEMNER

DSG1

311

Q02413
DGGWMVQFLEQSGLD

INF2

61

Q27J81
GMGEDFLSWNDLQAT

IQGAP3

496

Q86VI3
RGGTEQSLWDSQMEF

LRRC66

606

Q68CR7
SAQWALDDVLIGMND

RELN

1586

P78509
DDWENLLGSEPFAMQ

ETAA1

381

Q9NY74
MELAVGNLSEGNASW

GALR1

1

P47211
FQGDWGSDILDNMSD

DYNC2H1

2556

Q8NCM8
LMFWDLGGQEELQSL

ARFRP1

71

Q13795
LGMDDFTASNGWLDR

CENPB

111

P07199
DIFHWQIMDGNLTGN

HYI

186

Q5T013
TGGNVNLEEMLNDFW

GPC6

151

Q9Y625
FRVSTGDNWNGIMKD

CACNA1G

1796

O43497
WMQGAGILDASTAAQ

EBF4

31

Q9BQW3
GQAAQSGVWNDDSML

FBXO7

126

Q9Y3I1
AGEGMGSLRSANWEE

CDHR3

826

Q6ZTQ4
MVDGSWSIGDENFNK

COL14A1

1036

Q05707
MGDWSFLGNILEEVN

GJA8

1

P48165
SALGAMGQWQLEVGD

DPCD

56

Q9BVM2
EIMAGWTADDSNLNT

DENND4C

1506

Q5VZ89
QDDLGAAFQTWMDTS

COL27A1

1626

Q8IZC6
AFWQALDENMDLLEG

EIF3K

116

Q9UBQ5
GRLEFANGGWVMNDE

MAN2B1

146

O00754
TWNLMEGENSLDDFE

IFIT2

21

P09913
WSLDPASQDMFDNGS

FOXD4L1

181

Q9NU39
GLQAKGWNFMLEDST

GLB1L2

46

Q8IW92
LAGFGNLRGQMEVWD

EIF2A

331

Q9BY44
MGDWSFLGRLLENAQ

GJA3

1

Q9Y6H8
ADFAAGAMENWGLVT

NPEPPS

311

P55786
MFGRLDVATNDWTDG

DNAH5

2301

Q8TE73
MSPSAFGLNDWDDDE

OTUD5

526

Q96G74
QTGDNITWTFDMGDG

PKD1

1236

P98161
GQMGENDSFPAWAIV

MUCL3

436

Q3MIW9
MDIKGQFWNDDDSEG

PARP6

1

Q2NL67
GNDDQLWLVMEFCGA

MINK1

96

Q8N4C8
DNAEKWTMGTNGFNL

MMP20

206

O60882
SENSEDGAAWMQEPG

MSX2

106

P35548
SSAMANGNWEEAKEL

FAN1

616

Q9Y2M0
QGNLWEEMKDEGFSL

FOXN4

431

Q96NZ1
LSEMIAGDWLEANFS

SOX11

421

P35716
SEGEMVTFINWGNLN

EPRS1

561

P07814
SGGDEMNLSTSQWED

TNRC6C

881

Q9HCJ0
FSGWMDSMEANLNES

SYNE1

3401

Q8NF91
AVMDCGFGNWQDVAN

TADA2A

86

O75478
AIEQFGFGNWEDMAA

TADA2B

81

Q86TJ2
GINAALGNMEEDNWR

SDHA

106

P31040
WQANMILDDGGDLTH

AHCYL1

221

O43865
MGFLEEEGRWNLSFS

PNPLA5

1

Q7Z6Z6
GAWFLEELCSMSGNV

SMG1

2801

Q96Q15
ADGQTEQRGINLWEM

NAGPA

256

Q9UK23
QWGAEEESMFFSNPL

PSD4

236

Q8NDX1
FMILASDGLWDAFSN

PPM1L

296

Q5SGD2
FEMDASNLGGWSLNK

TENM1

1126

Q9UKZ4
GSEMAGNEAWLESES

SPATA31E1

991

Q6ZUB1
GCDWSQNNKDMIATG

WDR17

526

Q8IZU2
DNQMAQGSLFWDDGE

SI

1716

P14410
EDLQGMGESNCAWNR

NDUFAF5

256

Q5TEU4
LSFGPQENFWEMGDT

AARS2

201

Q5JTZ9
MGNPLDKGSDSVWNF

TGM3

316

Q08188
DSQASGDAFWGARML

ANHX

356

E9PGG2
DQWSELFMDALGPFN

INPP5J

481

Q15735
MGLLASSVNEFGQSW

TECTA

1256

O75443
DALGMEGDFNASSGW

TIGD2

111

Q4W5G0
MDDLATLDGQNWLND

SENP5

571

Q96HI0
LWFVMEFCEGGDLNQ

STK35

311

Q8TDR2
ESFSWDFAQAGEMLL

TICRR

246

Q7Z2Z1
AMGNGLRADVWETFQ

SLC27A5

406

Q9Y2P5
GNEAEIWLGLNDMAA

CLEC3B

126

P05452
TDGSLQSEDWALNME

TOM1

21

O60784
LGWAMTSADLNQDGH

GPLD1

381

P80108
NIFNGDADLSGMTWS

SERPINB4

306

P48594
NTLSAKWADNFMAEG

SLC35F6

21

Q8N357
FEGSSWDMGNLSLAL

SLC7A6

226

Q92536
DDGQWSQGLISAARM

TLN2

2386

Q9Y4G6
LTEAMGGGWQQEQFE

SWAP70

146

Q9UH65
RGNWAMLEGSAGADA

WDR4

341

P57081
SNSELCGMDQFWGIA

USP34

1091

Q70CQ2
DTLVLGDMDGNLNFW

WDR11

721

Q9BZH6
GDMDGNLNFWDLKGR

WDR11

726

Q9BZH6
WASENGETDAEGTQM

GTF3C1

1866

Q12789
GDRTMLDSLWAAGQE

TKFC

491

Q3LXA3
SGASDNSIIMWDIGG

WDFY1

216

Q8IWB7
DDSAATGMVKSNQWG

TNRC6A

806

Q8NDV7
MLSKDGFWNSNFGEA

ZNF473

101

Q8WTR7
AALGTGWESMNVQLD

ZNF641

21

Q96N77
PQEGNTGDWEMAAAL

ZNF641

86

Q96N77
FILADAGFDVWMGNS

LIPA

106

P38571
ATTQMFHEDAAGGWQ

NALCN

346

Q8IZF0
DHDTGEQVMNSGWAN

MYO7A

1636

Q13402