Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioninositol 1,4,5-trisphosphate-gated calcium channel activity

ITPR1 ITPR2

5.36e-053852GO:0005220
DomainARM-type_fold

DCAF1 RIF1 GBF1 RPTOR RTTN ARMC10 TRRAP VIRMA ITPR1 ITPR2

3.18e-063398510IPR016024
DomainInsP3_rcpt-bd

ITPR1 ITPR2

6.12e-053852IPR000493
DomainIMS

POLH REV1

1.22e-044852PF00817
DomainIMS_C

POLH REV1

1.22e-044852PF11799
DomainUMUC

POLH REV1

1.22e-044852PS50173
Domain-

POLH REV1

1.22e-0448523.30.1490.100
DomainDNA_pol_Y-fam_little_finger

POLH REV1

1.22e-044852IPR017961
DomainLaminin_aI

LAMA1 LAMA2

2.03e-045852IPR009254
DomainLaminin_I

LAMA1 LAMA2

2.03e-045852PF06008
DomainLaminin_II

LAMA1 LAMA2

2.03e-045852PF06009
DomainLaminin_domII

LAMA1 LAMA2

2.03e-045852IPR010307
DomainRIH_assoc

ITPR1 ITPR2

3.03e-046852PF08454
DomainRIH_assoc-dom

ITPR1 ITPR2

3.03e-046852IPR013662
DomainRIH_dom

ITPR1 ITPR2

3.03e-046852IPR000699
DomainIns145_P3_rcpt

ITPR1 ITPR2

3.03e-046852IPR014821
DomainRyanodine_recept-rel

ITPR1 ITPR2

3.03e-046852IPR015925
Domain-

ITPR1 ITPR2

3.03e-0468521.25.10.30
DomainRYDR_ITPR

ITPR1 ITPR2

3.03e-046852PF01365
DomainIns145_P3_rec

ITPR1 ITPR2

3.03e-046852PF08709
DomainUmuC

POLH REV1

3.03e-046852IPR001126
Domain-

DCAF1 RIF1 RPTOR RTTN ARMC10 TRRAP

5.28e-042228561.25.10.10
DomainLAMININ_IVA

LAMA1 LAMA2

5.63e-048852PS51115
DomainLaminin_B

LAMA1 LAMA2

5.63e-048852PF00052
DomainLamB

LAMA1 LAMA2

5.63e-048852SM00281
DomainLaminin_IV

LAMA1 LAMA2

5.63e-048852IPR000034
DomainMIR

ITPR1 ITPR2

9.00e-0410852PS50919
DomainMIR

ITPR1 ITPR2

9.00e-0410852PF02815
DomainMIR

ITPR1 ITPR2

9.00e-0410852SM00472
DomainMIR_motif

ITPR1 ITPR2

9.00e-0410852IPR016093
DomainLaminin_G_1

LAMA1 LAMA2

1.10e-0311852PF00054
DomainARM-like

DCAF1 RIF1 RPTOR RTTN ARMC10 TRRAP

1.45e-03270856IPR011989
DomainIon_trans_dom

TPTE TRPM7 ITPR1 ITPR2

1.82e-03114854IPR005821
DomainIon_trans

TPTE TRPM7 ITPR1 ITPR2

1.82e-03114854PF00520
DomainSTART

STARD9 CERT1

2.07e-0315852PF01852
DomainSTART_lipid-bd_dom

STARD9 CERT1

2.07e-0315852IPR002913
DomainSTART

STARD9 CERT1

2.07e-0315852PS50848
DomainLaminin_N

LAMA1 LAMA2

2.36e-0316852IPR008211
DomainLAMININ_NTER

LAMA1 LAMA2

2.36e-0316852PS51117
DomainLaminin_N

LAMA1 LAMA2

2.36e-0316852PF00055
DomainLamNT

LAMA1 LAMA2

2.36e-0316852SM00136
Domain-

DCAF1 DMXL2 DCAF13 ARHGEF10 RPTOR PLXND1

4.13e-033338562.130.10.10
DomainWD40/YVTN_repeat-like_dom

DCAF1 DMXL2 DCAF13 ARHGEF10 RPTOR PLXND1

4.25e-03335856IPR015943
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

GPHN TNK1 KIF23 GBF1 HIVEP2 CARMIL2 ACACA TRPM7 ARHGEF10 STARD9 RPTOR SYNE2 MAD1L1 CEP192 VIRMA

2.56e-09861851536931259
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

ZNF276 GBF1 HIVEP2 ACACA SETD5 RPTOR RTTN KAT6A MAD1L1 MICAL3 CEP192 PLXND1 IDUA MAPKAPK5 TRRAP ITPR2

9.74e-091105851635748872
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

RIF1 KIF23 GBF1 ACACA RPTOR MAD1L1 YLPM1 MICAL3 NIBAN2 TRRAP VIRMA BAG6 RAD50

5.03e-08774851315302935
Pubmed

C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.

GPHN DMXL2 GBF1 TRPM7 VPS13C RPTOR SYNE2 BAG6 ITPR1 ITPR2

4.43e-07504851034432599
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

NCOA2 GABRE HIVEP2 ACACA SETD5 VPS13C RPTOR SDCCAG8 KAT6A MAD1L1 MICAL3 CEP192 TRRAP CERT1 SAP130 ZNF461

5.67e-071489851628611215
Pubmed

BRCA1 promotes the ubiquitination of PCNA and recruitment of translesion polymerases in response to replication blockade.

POLH HLTF REV1

1.17e-06985323901102
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

TPTE RIF1 SYNE2 YLPM1 MICAL3 CEP192 CACHD1 NIBAN2 COLGALT1 MAPK9 TTC33 ITPR1 ITPR2

1.57e-061049851327880917
Pubmed

Genome-wide association study of selenium concentrations.

ARHGEF10 SDCCAG8 ZNF521 CMYA5

1.64e-063585425343990
Pubmed

Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro.

GPHN STARD9 VPS13C RPTOR MICAL3 VIRMA

2.16e-0615385610718198
Pubmed

Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.

PLSCR4 DCAF1 KANK1 SALL1 THRSP TRPM7 GUSB KAT6A GATB HNF4A GMPPA SAP130 ITPR2 REV1

2.90e-061293851415342556
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

DCAF1 DMXL2 DCAF13 TRPM7 ARHGEF10 GUSB SYNE2 GATB CEP192 NIBAN2 COLGALT1 BAG6 VCL ITPR1 ITPR2

2.92e-061487851533957083
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

RIF1 KIF23 DCAF13 ACACA SYNE2 YLPM1 TRRAP VIRMA VCL RAD50

4.49e-06653851022586326
Pubmed

Transgenic overexpression of laminin alpha1 chain in laminin alpha2 chain-deficient mice rescues the disease throughout the lifespan.

LAMA1 LAMA2

5.90e-06285220544910
Pubmed

Genetic and physical interactions between Polη and Rev1 in response to UV-induced DNA damage in mammalian cells.

POLH REV1

5.90e-06285234725419
Pubmed

Conserved neuron promoting activity in Drosophila and vertebrate laminin alpha1.

LAMA1 LAMA2

5.90e-0628528663504
Pubmed

Laminin α1 reduces muscular dystrophy in dy2J mice.

LAMA1 LAMA2

5.90e-06285229544677
Pubmed

Chlamydia trachomatis co-opts GBF1 and CERT to acquire host sphingomyelin for distinct roles during intracellular development.

GBF1 CERT1

5.90e-06285221909260
Pubmed

Expression of the MOZ-TIF2 oncoprotein in mice represses senescence.

NCOA2 KAT6A

5.90e-06285226854485
Pubmed

Laminin 2 attachment selects myofibroblasts from fetal mouse lung.

LAMA1 LAMA2

5.90e-0628529728058
Pubmed

Lack of zinc finger protein 521 upregulates dopamine β-hydroxylase expression in the mouse brain, leading to abnormal behavior.

ZNF521 DBH

5.90e-06285231200001
Pubmed

NMR structure and dynamics of the C-terminal domain from human Rev1 and its complex with Rev1 interacting region of DNA polymerase η.

POLH REV1

5.90e-06285222691049
Pubmed

An antidepressant behaviour in mice carrying a gene-specific InsP3R1, InsP3R2 and InsP3R3 protein knockdown.

ITPR1 ITPR2

5.90e-06285218708078
Pubmed

Immunolocalization of type 2 inositol 1,4,5-trisphosphate receptors in cardiac myocytes from newborn mice.

ITPR1 ITPR2

5.90e-06285215201137
Pubmed

Post-replication repair: Rad5/HLTF regulation, activity on undamaged templates, and relationship to cancer.

HLTF RAD50

5.90e-06285231429594
Pubmed

Analysis of mice deficient in both REV1 catalytic activity and POLH reveals an unexpected role for POLH in the generation of C to G and G to C transversions during Ig gene hypermutation.

POLH REV1

5.90e-06285222223762
Pubmed

Sulphide signalling potentiates apoptosis through the up-regulation of IP3 receptor types 1 and 2.

ITPR1 ITPR2

5.90e-06285223582047
Pubmed

MICAL3 Flavoprotein Monooxygenase Forms a Complex with Centralspindlin and Regulates Cytokinesis.

KIF23 MICAL3

5.90e-06285227528609
Pubmed

Interaction with DNA polymerase eta is required for nuclear accumulation of REV1 and suppression of spontaneous mutations in human cells.

POLH REV1

5.90e-06285219157994
Pubmed

A novel fusion between MOZ and the nuclear receptor coactivator TIF2 in acute myeloid leukemia.

NCOA2 KAT6A

5.90e-0628529558366
Pubmed

Distinct roles for laminin globular domains in laminin alpha1 chain mediated rescue of murine laminin alpha2 chain deficiency.

LAMA1 LAMA2

5.90e-06285220657839
Pubmed

Type 1 and 2 IP3 receptors respond differently to catecholamines and stress.

ITPR1 ITPR2

5.90e-06285219120126
Pubmed

Characterization of an MPS I-H knock-in mouse that carries a nonsense mutation analogous to the human IDUA-W402X mutation.

GUSB IDUA

5.90e-06285219751987
Pubmed

mTORC1 hyperactivation arrests bone growth in lysosomal storage disorders by suppressing autophagy.

GUSB RPTOR

5.90e-06285228872463
Pubmed

Defining the human deubiquitinating enzyme interaction landscape.

DCAF1 GPHN HIVEP2 ARHGEF10 YLPM1 HLTF CEP192 NIBAN2 TRRAP CERT1 BAG6 RAD50

6.01e-061005851219615732
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

NCOA2 GPHN KIF23 ACACA YLPM1 TRRAP SAP130 VCL RAD50

8.10e-0654985938280479
Pubmed

Human transcription factor protein interaction networks.

NCOA2 RIF1 KIF23 SALL1 POLH SYNE2 YLPM1 ZNF521 CEP192 HNF4A TRRAP SAP130 VCL RAD50

9.08e-061429851435140242
Pubmed

Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization.

NCOA2 GBF1 TRPM7 CCDC141

1.19e-055785424952745
Pubmed

Evidence that type I, II, and III inositol 1,4,5-trisphosphate receptors can occur as integral plasma membrane proteins.

ITPR1 ITPR2

1.77e-05385210874040
Pubmed

Expression of inositol 1,4,5-trisphosphate receptors in mouse oocytes and early embryos: the type I isoform is upregulated in oocytes and downregulated after fertilization.

ITPR1 ITPR2

1.77e-0538529808793
Pubmed

Molecular Pap smear: HPV genotype and DNA methylation of ADCY8, CDH8, and ZNF582 as an integrated biomarker for high-grade cervical cytology.

ZNF582 ADCY8

1.77e-05385227651839
Pubmed

Abnormal distribution of inositol 1,4,5-trisphosphate receptors in human muscle can be related to altered calcium signals and gene expression in Duchenne dystrophy-derived cells.

ITPR1 ITPR2

1.77e-05385220395455
Pubmed

Inositol 1,4,5-trisphosphate receptors are autoantibody target antigens in patients with Sjögren's syndrome and other systemic rheumatic diseases.

ITPR1 ITPR2

1.77e-05385217437169
Pubmed

Zn2+ is essential for Ca2+ oscillations in mouse eggs.

TRPM7 ITPR1

1.77e-05385238099643
Pubmed

Type 2 and type 3 inositol 1,4,5-trisphosphate (IP3) receptors promote the differentiation of granule cell precursors in the postnatal cerebellum.

ITPR1 ITPR2

1.77e-05385218194433
Pubmed

Decreased olfactory mucus secretion and nasal abnormality in mice lacking type 2 and type 3 IP3 receptors.

ITPR1 ITPR2

1.77e-05385218547250
Pubmed

Inositol 1,4,5-trisphosphate receptor gene variants are related to the risk of breast cancer in a Chinese population.

ITPR1 ITPR2

1.77e-05385236350267
Pubmed

Inositol 1,4,5-trisphosphate receptors are essential for fetal-maternal connection and embryo viability.

ITPR1 ITPR2

1.77e-05385232320395
Pubmed

IP3 receptors regulate vascular smooth muscle contractility and hypertension.

ITPR1 ITPR2

1.77e-05385227777977
Pubmed

The versatility and universality of calcium signalling.

ITPR1 ITPR2

1.77e-05385211413485
Pubmed

Stalled Polη at its cognate substrate initiates an alternative translesion synthesis pathway via interaction with REV1.

POLH REV1

1.77e-05385222244149
Pubmed

Using concatenated subunits to investigate the functional consequences of heterotetrameric inositol 1,4,5-trisphosphate receptors.

ITPR1 ITPR2

1.77e-05385226009177
Pubmed

Differential inositol 1,4,5-trisphosphate receptor signaling in a neuronal cell line.

ITPR1 ITPR2

1.77e-05385217581770
Pubmed

Predominant role of type 1 IP3 receptor in aortic vascular muscle contraction.

ITPR1 ITPR2

1.77e-05385218241669
Pubmed

Differential expression of laminin isoforms and alpha 6-beta 4 integrin subunits in the developing human and mouse intestine.

LAMA1 LAMA2

1.77e-0538527803849
Pubmed

Mechanism of shortened bones in mucopolysaccharidosis VII.

GUSB IDUA

1.77e-05385219375967
Pubmed

Receptor-activated single channels in intact human platelets.

ITPR1 ITPR2

1.77e-0538521693919
Pubmed

Granulosa cells express three inositol 1,4,5-trisphosphate receptor isoforms: cytoplasmic and nuclear Ca2+ mobilization.

ITPR1 ITPR2

1.77e-05385219068129
Pubmed

Functional inositol 1,4,5-trisphosphate receptors assembled from concatenated homo- and heteromeric subunits.

ITPR1 ITPR2

1.77e-05385223955339
Pubmed

Type 3 Inositol 1,4,5-Trisphosphate Receptor is a Crucial Regulator of Calcium Dynamics Mediated by Endoplasmic Reticulum in HEK Cells.

ITPR1 ITPR2

1.77e-05385231979185
Pubmed

Mutational analysis of the C8-guanine adduct of the environmental carcinogen 3-nitrobenzanthrone in human cells: critical roles of DNA polymerases η and κ and Rev1 in error-prone translesion synthesis.

POLH REV1

1.77e-05385225080294
Pubmed

Translesion synthesis mechanisms depend on the nature of DNA damage in UV-irradiated human cells.

POLH REV1

1.77e-05385227095204
Pubmed

Tsg101 regulates PI(4,5)P2/Ca(2+) signaling for HIV-1 Gag assembly.

ITPR1 ITPR2

1.77e-05385224904548
Pubmed

Molecular basis of the isoform-specific ligand-binding affinity of inositol 1,4,5-trisphosphate receptors.

ITPR1 ITPR2

1.77e-05385217327232
Pubmed

The HNF4A-CHPF pathway promotes proliferation and invasion through interactions with MAD1L1 in glioma.

MAD1L1 HNF4A

1.77e-05385237851364
Pubmed

Type 1 inositol (1,4,5)-trisphosphate receptor activates ryanodine receptor 1 to mediate calcium spark signaling in adult mammalian skeletal muscle.

ITPR1 ITPR2

1.77e-05385223223241
Pubmed

Nuclear inositol 1,4,5-trisphosphate receptors regulate local Ca2+ transients and modulate cAMP response element binding protein phosphorylation.

ITPR1 ITPR2

1.77e-05385216014380
Pubmed

Expression of laminin chains during myogenic differentiation.

LAMA1 LAMA2

1.77e-0538527510707
Pubmed

Dystroglycan is a binding protein of laminin and merosin in peripheral nerve.

LAMA1 LAMA2

1.77e-0538527925941
Pubmed

Laminin alpha1 chain mediated reduction of laminin alpha2 chain deficient muscular dystrophy involves integrin alpha7beta1 and dystroglycan.

LAMA1 LAMA2

1.77e-05385216504180
Pubmed

Knockdown of the type 2 and 3 inositol 1,4,5-trisphosphate receptors suppresses muscarinic antinociception in mice.

ITPR1 ITPR2

1.77e-05385217890015
Pubmed

Inositol 1, 4, 5-trisphosphate receptors and human left ventricular myocytes.

ITPR1 ITPR2

1.77e-05385223983250
Pubmed

Differential distribution of inositol trisphosphate receptor isoforms in mouse oocytes.

ITPR1 ITPR2

1.77e-0538529858485
Pubmed

MOZ-TIF2-induced acute myeloid leukemia requires the MOZ nucleosome binding motif and TIF2-mediated recruitment of CBP.

NCOA2 KAT6A

1.77e-05385212676584
Pubmed

Differential roles for DNA polymerases eta, zeta, and REV1 in lesion bypass of intrastrand versus interstrand DNA cross-links.

POLH REV1

1.77e-05385220028736
Pubmed

Activation of the inositol (1,4,5)-triphosphate calcium gate receptor is required for HIV-1 Gag release.

ITPR1 ITPR2

1.77e-05385220427533
Pubmed

DNA-damage tolerance mediated by PCNA*Ub fusions in human cells is dependent on Rev1 but not Polη.

POLH REV1

1.77e-05385223761444
Pubmed

HAT cofactor Trrap regulates the mitotic checkpoint by modulation of Mad1 and Mad2 expression.

MAD1L1 TRRAP

1.77e-05385215549134
Pubmed

Brain alpha-dystroglycan displays unique glycoepitopes and preferential binding to laminin-10/11.

LAMA1 LAMA2

1.77e-05385216709410
Pubmed

Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.

RIF1 DCAF13 MAD1L1 YLPM1 TRRAP SAP130 ITPR2

2.10e-0534185732971831
Pubmed

Systematic analysis of human protein complexes identifies chromosome segregation proteins.

DCAF1 GPHN KANK1 KIF23 MAD1L1 YLPM1 MICAL3 CEP192 NIBAN2 VCL TTC33 ITPR1

2.40e-051155851220360068
Pubmed

siRNA screening identifies differences in the Fanconi anemia pathway in BALB/c-Trp53+/- with susceptibility versus C57BL/6-Trp53+/- mice with resistance to mammary tumors.

ACACA POLH REV1

3.52e-052685323435420
Pubmed

Vinculin: a novel marker for quiescent and activated hepatic stellate cells in human and rat livers.

RPTOR VCL

3.53e-05485212719976
Pubmed

Loss of IP3R-dependent Ca2+ signalling in thymocytes leads to aberrant development and acute lymphoblastic leukemia.

ITPR1 ITPR2

3.53e-05485225215520
Pubmed

MOZ-TIF2 alters cofactor recruitment and histone modification at the RARbeta2 promoter: differential effects of MOZ fusion proteins on CBP- and MOZ-dependent activators.

NCOA2 KAT6A

3.53e-05485216613851
Pubmed

Inositol 1, 4, 5-trisphosphate receptor interacts with the SNARE domain of syntaxin 1B.

ITPR1 ITPR2

3.53e-05485221424589
Pubmed

Bromodomain-PHD finger protein 1 is critical for leukemogenesis associated with MOZ-TIF2 fusion.

NCOA2 KAT6A

3.53e-05485224258712
Pubmed

Rev1 plays central roles in mammalian DNA-damage tolerance in response to UV irradiation.

POLH REV1

3.53e-05485230963698
Pubmed

Selective regulation of IP3-receptor-mediated Ca2+ signaling and apoptosis by the BH4 domain of Bcl-2 versus Bcl-Xl.

ITPR1 ITPR2

3.53e-05485221818117
Pubmed

Cleft palate and minor metabolic disturbances in a mouse global Arl15 gene knockout.

TRPM7 VCL

3.53e-05485237773757
Pubmed

Loss of IP3 Receptor-Mediated Ca2+ Release in Mouse B Cells Results in Abnormal B Cell Development and Function.

ITPR1 ITPR2

3.53e-05485228615414
Pubmed

Identification of a novel REV1-interacting motif necessary for DNA polymerase kappa function.

POLH REV1

3.53e-05485219170759
Pubmed

Laminin alpha 1, alpha 2, alpha 4 and beta 1 chain mRNA expression in mouse embryonic, neonatal, and adult hearts.

LAMA1 LAMA2

3.53e-0548529201115
Pubmed

Distinct localization and function of (1,4,5)IP(3) receptor subtypes and the (1,3,4,5)IP(4) receptor GAP1(IP4BP) in highly purified human platelet membranes.

ITPR1 ITPR2

3.53e-05485210828023
Pubmed

HIV-1 Vpr protein directly loads helicase-like transcription factor (HLTF) onto the CRL4-DCAF1 E3 ubiquitin ligase.

DCAF1 HLTF

3.53e-05485229079575
Pubmed

Requirement of JNK2 for scavenger receptor A-mediated foam cell formation in atherogenesis.

MSR1 MAPK9

3.53e-05485215567863
Pubmed

Organisation of extracellular matrix proteins laminin and agrin in pericapillary basal laminae in mouse brain.

LAMA1 LAMA2

3.53e-05485232072250
Pubmed

The C-terminal domain of human Rev1 contains independent binding sites for DNA polymerase η and Rev7 subunit of polymerase ζ.

POLH REV1

3.53e-05485222828282
Pubmed

Distribution and isolation of four laminin variants; tissue restricted distribution of heterotrimers assembled from five different subunits.

LAMA1 LAMA2

3.53e-0548522099832
Pubmed

IP3R-mediated Ca2+ signals govern hematopoietic and cardiac divergence of Flk1+ cells via the calcineurin-NFATc3-Etv2 pathway.

ITPR1 ITPR2

3.53e-05485228419336
Pubmed

Crystal structure of Spot 14, a modulator of fatty acid synthesis.

THRSP ACACA

3.53e-05485220952656
InteractionYWHAG interactions

GPHN TNK1 KANK1 KIF23 GBF1 HIVEP2 CARMIL2 TRPM7 STARD9 RPTOR SYNE2 MAD1L1 CEP192 MAPKAPK5 TRRAP VIRMA VCL

1.27e-0512488417int:YWHAG
InteractionYWHAZ interactions

TNK1 DMXL2 KANK1 KIF23 GBF1 HIVEP2 CARMIL2 TRPM7 STARD9 RPTOR SYNE2 KAT6A CEP192 MAPKAPK5 VIRMA VCL ITPR1

2.59e-0513198417int:YWHAZ
InteractionYWHAH interactions

NCOA2 TNK1 KANK1 KIF23 GBF1 HIVEP2 CARMIL2 TRPM7 STARD9 RPTOR SYNE2 MAD1L1 CEP192 VIRMA VCL

4.50e-0511028415int:YWHAH
InteractionNDC80 interactions

KANK1 DCAF13 TRPM7 SYNE2 MAD1L1 CEP192 VCL RAD50

4.74e-05312848int:NDC80
InteractionNR1I2 interactions

NCOA2 HNF4A TRRAP TFAP2C

4.75e-0548844int:NR1I2
InteractionUGT2A1 interactions

UGT2B15 TRRAP

5.14e-053842int:UGT2A1
InteractionSHPRH interactions

KAT6A HLTF TRRAP VIRMA SAP130

5.32e-0597845int:SHPRH
InteractionSIRT7 interactions

DCAF1 RIF1 KIF23 DCAF13 ACACA POLH SYNE2 YLPM1 TRRAP VIRMA VCL RAD50

5.79e-057448412int:SIRT7
InteractionH3-3A interactions

DCAF1 ZNF12 RIF1 KIF23 POLH KAT6A HLTF NIBAN2 HNF4A TRRAP SAP130 RAD50

6.17e-057498412int:H3-3A
InteractionRTTN interactions

KIF23 RTTN VIRMA

6.45e-0519843int:RTTN
InteractionZNF12 interactions

ZNF12 TRRAP VIRMA

7.57e-0520843int:ZNF12
GeneFamilyInositol 1,4,5-triphosphate receptors|Protein phosphatase 1 regulatory subunits

ITPR1 ITPR2

3.24e-053602297
GeneFamilyLaminin subunits

LAMA1 LAMA2

7.00e-0412602626
GeneFamilyStAR related lipid transfer domain containing

STARD9 CERT1

1.11e-0315602759
GeneFamilyZinc fingers ZZ-type|Lysine acetyltransferases

NCOA2 KAT6A

1.43e-0317602486
GeneFamilyWD repeat domain containing|DDB1 and CUL4 associated factors

DCAF1 DCAF13

1.60e-0318602498
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

NCOA2 RIF1 DMXL2 KIF23 GBF1 HIVEP2 ARHGEF10 SYNE2 KAT6A MAD1L1 HLTF MICAL3 TRRAP VCL ITPR1

9.71e-088568515M4500
CoexpressionPARENT_MTOR_SIGNALING_UP

GPHN GBF1 VPS13C SYNE2 KAT6A GATB LAMA2 CLSTN1 TBC1D8B ADCY8 RAD50

2.21e-065678511M16909
CoexpressionGSE37563_WT_VS_CTLA4_KO_CD4_TCELL_D4_POST_IMMUNIZATION_UP

RIF1 VPS13C GRAP2 KAT6A HLTF AK9

1.70e-05166856M9015
CoexpressionGSE38696_LIGHT_ZONE_VS_DARK_ZONE_BCELL_UP

RIF1 SDCCAG8 HLTF TBC1D8B ALS2CL CERT1

3.05e-05184856M9005
CoexpressionGSE39556_CD8A_DC_VS_NK_CELL_UP

DMXL2 KIF23 HIVEP2 HLTF PLXND1 VCL

4.85e-05200856M9406
CoexpressionGSE46606_DAY1_VS_DAY3_CD40L_IL2_IL5_STIMULATED_IRF4MID_BCELL_DN

ARHGEF10 HLTF CEP192 MAPK9 TBC1D8B TTC33

4.85e-05200856M9842
CoexpressionHAMAI_APOPTOSIS_VIA_TRAIL_UP

ZNF12 RIF1 KIF23 VPS13C SYNE2 HLTF CEP192 ITPR1 ITPR2 RAD50

5.21e-056568510M18979
ToppCell10x5'-Lung-Lymphocytic_Invariant-Inducer-like-ILC3|Lung / Manually curated celltypes from each tissue

PLSCR4 STARD9 POLH GATB MICAL3 AK9 TTC33

7.19e-081878570e7aa481effdd8c2fbdf8b65852821dec2d92cde
ToppCellCV-Moderate-7|CV / Virus stimulation, Condition and Cluster

DMXL2 GBF1 SUGCT TRPM7 VPS13C ITPR2

1.54e-061868568571956890fc9894d766ba294a28e376b4aba428
ToppCellRV-06._Ventricular_Cardiomyocyte_II|World / Chamber and Cluster_Paper

KANK1 TRPM7 LAMA2 MICAL3 CMYA5 CCDC141

1.69e-061898565e80c47f63980904c4c1ff02c201b67b456a0974
ToppCellRV-06._Ventricular_Cardiomyocyte_II|RV / Chamber and Cluster_Paper

KANK1 TRPM7 LAMA2 MICAL3 CMYA5 CCDC141

1.74e-06190856fe8e78922c8ae928ef9a80bffd67868d5a87a091
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2|Children_(3_yrs) / Lineage, Cell type, age group and donor

GPHN KANK1 ACACA CACHD1 CCDC141 ADCY8

1.79e-06191856a0332a4ef629510fb313ec119195c44a3f704a80
ToppCellEpithelial-alveolar_epithelial_cell_type_2|World / Lineage, Cell type, age group and donor

GPHN KANK1 ACACA CACHD1 CCDC141 ADCY8

1.85e-0619285658c3737be7acce39fd2b91d70d6d7b2bbaa4f710
ToppCellParenchymal-10x3prime_v2-Immune_Myeloid-Myeloid-Megakaryocyte|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

KAT6A YLPM1 AK9 TRRAP SAP130 ITPR1

2.34e-062008560d76b006d8e8b32174e65e400acd0674354b962c
ToppCellParenchymal-10x3prime_v2-Immune_Myeloid-Myeloid|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

KAT6A YLPM1 AK9 TRRAP SAP130 ITPR1

2.34e-06200856cc8368665bc6bb7c4f39632ccff07ceaa98a7b65
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SUGCT SYNE2 SLC13A2 HNF4A ADCY8

2.20e-051768551595dbeee336a81e581325d63208ec6262664ee9
ToppCellControl-Epithelial_cells-AT2|Control / group, cell type (main and fine annotations)

GPHN KANK1 ACACA CACHD1 CCDC141

2.45e-05180855198b19e7910b4a8cc7e820c525ab357c7f99f578
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KANK1 TRPM7 CACHD1 ABCA9 ITPR1

2.52e-05181855e0abf2707d9e0aa942c657eef7d2cbcd02f060dd
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1_FGFR3_MT1G|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PLSCR4 KANK1 LAMA1 CACHD1 TFAP2C

2.52e-051818550c3f469bed108994ed696230e3c30343f7a301d3
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MSR1 KANK1 TRPM7 CACHD1 ITPR1

2.59e-051828555f513bbb7125956eb528e3120de3fd776770a7c3
ToppCell3'_v3-lymph-node_spleen-Myeloid_Mac-Cycling_Myeloid-Mac|lymph-node_spleen / Manually curated celltypes from each tissue

MSR1 KIF23 GATB IDUA GMPPA

2.59e-0518285584018a84e1aa52fa52ccfc26db9cd1fb6d535b31
ToppCellCOVID-19_Mild-Lymphoid_T/NK-CD4+_T_activated|COVID-19_Mild / Disease group, lineage and cell class

HIVEP2 CARMIL2 SYNE2 ALS2CL VIRMA

2.66e-051838557717fce227b4e02ed41baad8ae7dd2e22bd7c13e
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

KANK1 ACACA CACHD1 CCDC141 ADCY8

2.66e-051838556847c1252d6bb105524f812658112517fd351eab
ToppCell10x_5'_v1-Non-neoplastic-Myeloid-Mono-Mono_anti-infl-Z|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MSR1 DMXL2 PLXND1 COLGALT1 TBC1D8B

2.87e-05186855f73cb91e74a806858650ae97f543fc779ba4cff8
ToppCell10x_5'_v1-Non-neoplastic-Myeloid-Mono-Mono_anti-infl|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MSR1 DMXL2 PLXND1 COLGALT1 TBC1D8B

2.87e-051868558694ca16c9780729f4fba67ba20e35745f1eb4e9
ToppCellControl-Fibroblasts-Other_FB|Control / group, cell type (main and fine annotations)

PLSCR4 SUGCT LAMA2 ZNF521 ABCA9

2.95e-05187855bd3739c4a52aa1ba5deffd778e113a9800f7e158
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KANK1 TRPM7 LAMA1 CACHD1 ITPR1

3.02e-05188855bc089cd73d283ed7d2ecbb3936673b4edc89f666
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KANK1 TRPM7 LAMA1 CACHD1 ITPR1

3.02e-05188855eec3d353e51358db4c7621265ee0fdd4298e5b0e
ToppCellRV-04._Ventricular_Cardiomyocyte_I|RV / Chamber and Cluster_Paper

TRPM7 MICAL3 CMYA5 CCDC141 VCL

3.10e-051898559c1debd65c13d63fd4f3158917d621b44b714c26
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

KANK1 TRPM7 LAMA1 CACHD1 ITPR1

3.10e-05189855975c0f079903ae36b0ffa54e86294d42ec7697de
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

KANK1 TRPM7 LAMA1 CACHD1 ITPR1

3.10e-051898557eb8f5a951e80f1cfac4d7c9eb169f4eb100c917
ToppCelldroplet-Heart-nan-24m-Endothelial-endocardial_endothelial_cells|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KANK1 SALL1 ZNF521 PLPPR5 PLXND1

3.10e-051898551137583e21d874c201c20581ba1995e2bfa3de59
ToppCellLV-06._Ventricular_Cardiomyocyte_II|World / Chamber and Cluster_Paper

KANK1 TRPM7 LAMA2 CMYA5 CCDC141

3.18e-05190855de5ef606a002f85c2e0e3a36c1f259d0b85a76ff
ToppCelldroplet-Heart-nan-24m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KANK1 SALL1 ZNF521 PLPPR5 PLXND1

3.18e-051908557068754c29f63a331e2b6c54715f3b26f37ad32b
ToppCellLV-06._Ventricular_Cardiomyocyte_II|LV / Chamber and Cluster_Paper

KANK1 TRPM7 LAMA2 CMYA5 CCDC141

3.26e-0519185525f3eb34f4e70761e81e84c8a5829f216108cbc6
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT2-AT2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

GPHN KANK1 ACACA CACHD1 CCDC141

3.42e-05193855fd4d3c0d7caf8a2fff5b3d901fc28d19a8163cdf
ToppCellCOVID-19-Fibroblasts-Other_FB|COVID-19 / group, cell type (main and fine annotations)

PLSCR4 SUGCT LAMA2 ZNF521 ABCA9

3.42e-05193855e6b75be08e33c1de079fb5c02f0b4468128b369c
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2|Adult / Lineage, Cell type, age group and donor

GPHN KANK1 ACACA CACHD1 CCDC141

3.42e-05193855738f4f0a9ddde2432b429ab46838e353b1790589
ToppCellhuman_hepatoblastoma-Tumor_cells|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)

KANK1 SUGCT RPTOR HNF4A ITPR2

3.42e-05193855503a979328c68b096680b71359a26f02fafdff35
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

GPHN KANK1 ACACA CACHD1 CCDC141

3.42e-05193855f3cc7cfdbc164a4ed42f87647111522b7d393bcb
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

GPHN KANK1 SYNE2 MICAL3 CMYA5

3.51e-051948557002937e8903e037332a215d00fbc7c7843b33f2
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

GPHN KANK1 ACACA NIBAN2 CCDC141

3.51e-0519485597534c8bba895a7913665e03ae4e5c4a6ad71daf
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KANK1 TRPM7 CACHD1 ABCA9 ITPR1

3.60e-05195855a38d9dc6192aea673d96fda6b25e81223fda3abf
ToppCellT_cells-Treg_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

GPHN HIVEP2 FCRL3 SYNE2 CCDC141

3.78e-05197855de5448fcdf4e433fc167496413abe5d0c8a5c6d8
ToppCell5'-Adult-Appendix-Endothelial-lymphatic_endothelial-LEC1_(ACKR4+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DCAF1 STARD9 HLTF PLXND1 BAG6

3.78e-05197855789c97ca9d1e28df3353140046047f11fbccc1d0
ToppCellParenchymal-NucSeq-Epithelial-Epi_alveolar-AT2|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

KANK1 ACACA SDCCAG8 CACHD1 CCDC141

3.87e-051988552e2a4e1756bba6f4fbe529559a97d2993c890b4b
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW08-Stem_cells|GW08 / Sample Type, Dataset, Time_group, and Cell type.

RIF1 SALL1 POLH TRRAP VCL

4.06e-05200855691b3edf7d8449556e8bf611662eb85772959f0f
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW08-Stem_cells-Stem_cells|GW08 / Sample Type, Dataset, Time_group, and Cell type.

RIF1 SALL1 POLH TRRAP VCL

4.06e-0520085536a110aa91a791fdf1142e7869e8aa0d342402d0
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW08-Stem_cells-Neuroepithelial_cell|GW08 / Sample Type, Dataset, Time_group, and Cell type.

RIF1 SALL1 POLH TRRAP VCL

4.06e-052008554e077aa7faddcebdfc54667f8b3990704441005b
ToppCellCOVID-19-Myeloid-MoAM2,_CCL18|COVID-19 / Condition, Lineage and Cell class

DMXL2 NIBAN2 PLXND1 COLGALT1 ITPR2

4.06e-05200855b0a50622d00335843efad86bc56a1e910019984b
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW08-Stem_cells|GW08 / Sample Type, Dataset, Time_group, and Cell type.

RIF1 SALL1 POLH TRRAP VCL

4.06e-05200855d17ba4239e1fd702a3d757687110f0f2c6f91ef7
ToppCellmetastatic_Lymph_Node-T/NK_cells-CD8_low_T|T/NK_cells / Location, Cell class and cell subclass

MAD1L1 LAMA1 LAMA2 PLXND1

1.85e-04148854db046a02a00829910bf9d7dbda068e730aa78f00
ToppCellSubstantia_nigra-Macroglia-POLYDENDROCYTE|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

TNK1 KANK1 ARHGEF10 ITPR2

1.95e-0415085470ac8ae4b1683fb17278a8e4606f2fa0b94988c0
ToppCellprimary_visual_cortex-Non-neuronal-astrocyte|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

KANK1 LAMA2 CCDC141 ITPR2

2.10e-0415385495b28c5bd10ffb74c0993ebd565038b9818e4bd2
ToppCellprimary_visual_cortex-Non-neuronal-astrocyte-Astro|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

KANK1 LAMA2 CCDC141 ITPR2

2.10e-04153854b09f8def40a1ea56722f3398f61a036667b61cd9
ToppCellPBMC-Control-Lymphocyte-T/NK-CD4+_T-Treg-Treg_3|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

HIVEP2 FCRL3 SYNE2 CCDC141

2.10e-041538547480522a47e367f8facc4f5d599fbaf0b5ad4007
ToppCellprimary_visual_cortex-Non-neuronal-astrocyte-Astro-Astro_Aqp4|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

KANK1 LAMA2 CCDC141 ITPR2

2.10e-041538543ab9d55b3db51715c1d61eca142384195ce4b54f
ToppCellPBMC-Control-Lymphocyte-T/NK-CD4+_T-Treg-Treg_3|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

HIVEP2 FCRL3 SYNE2 CCDC141

2.26e-0415685453ded973358e3e48054130131e959f0d1f4ef60f
ToppCellCOVID-CD4-CD4_Treg|COVID / Condition, Cell_class and T cell subcluster

ZNF12 MSANTD3 VIRMA ZNF582

2.43e-04159854037cd97c41eb2f91fd3f69bbb3ffdfd6c0158410
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM7 CACHD1 ABCA9 ITPR1

2.49e-041608548bcdbcfdf1e0ace6053e8de82762f6e2f86bba7a
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM7 CACHD1 ABCA9 ITPR1

2.49e-041608542d391ba6f7adb55dfa89feecc10cc9ce97e5fe74
ToppCellVE-CD8-CD4_Treg|VE / Condition, Cell_class and T cell subcluster

FCRL3 ARHGEF10 PLXND1 CCDC141

2.55e-04161854a114f4f75859d9ef900e5146686438d051241429
ToppCell343B-Myeloid-Dendritic-cDC1|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

ZNF12 CARMIL2 GRAP2 DHTKD1

2.55e-04161854537a1d86de99a493b0345ca0f760994260e97049
ToppCell10x5'-lymph-node_spleen-Myeloid_Mac-Intermediate_macrophages|lymph-node_spleen / Manually curated celltypes from each tissue

MSR1 DMXL2 THRSP NIBAN2

2.80e-04165854c3fa9225d2f9c9e821d4fbd2315fcc98ce1f1c55
ToppCell343B-Myeloid-Macrophage-FABP4+_Macrophage|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

MSR1 GPHN CARMIL2 RTTN

2.87e-04166854f62db9d9b6c9dd8f2afcaea0fc5f8c69f50205b2
ToppCellmoderate-Myeloid-Mast_cell|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

GRAP2 HLTF ZNF521 CCDC141

2.87e-04166854c3835b424c63bf11a4e2c47635dc3787fc4a637a
ToppCellE18.5-Immune-Immune_Myeloid-DC-cDC2|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GUSB GRAP2 CEP192 TTC33

3.00e-0416885493b7138f17aa14a6398c9b4ea7237781a0e19a66
ToppCellE18.5-Immune-Immune_Myeloid-DC-cDC2-cDC2_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GUSB GRAP2 CEP192 TTC33

3.00e-04168854e393553208617a023f1646169c892a87c95db3f5
ToppCelldroplet-Marrow-nan-3m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MSR1 KAT6A MAPK9 ABCA9

3.07e-041698545f5bec13208f4c3b6eacbba180c8a6402743b76e
ToppCellRA-01._Fibroblast_I|RA / Chamber and Cluster_Paper

CARMIL2 LAMA2 CACHD1 ABCA9

3.07e-041698546373562ab3b1765060212a6a53d6543e7e942e80
ToppCellCOVID-19-Heart-CM_+_Macrophage|Heart / Disease (COVID-19 only), tissue and cell type

MSR1 DMXL2 CMYA5 CCDC141

3.14e-041708544232fe937909f93d3736988c707b8f95ce993398
ToppCellfacs-Marrow-T-cells-3m-Myeloid-promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MSR1 VPS13C PLXND1 ABCA9

3.14e-04170854a78d9789c3e7c84a36e1bd380192d7aba4a4d443
ToppCellfacs-Marrow-T-cells-3m-Myeloid-monocyte_+_promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MSR1 VPS13C PLXND1 ABCA9

3.14e-04170854ff68600b945b3a5437b14e5411b3db800d0ccbe5
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KANK1 TRPM7 ABCA9 ITPR1

3.35e-041738540c74bdb40e635d906fd180412c23bf7fed61621e
ToppCellBrain_organoid-organoid_Tanaka_cellReport-5w-Mesenchymal-Cilia-bearing_cell|5w / Sample Type, Dataset, Time_group, and Cell type.

SALL1 MAD1L1 ZNF521 CACHD1

3.35e-04173854d4cbeae262abfa30d8c5452285d3261a96875610
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KANK1 TRPM7 CACHD1 ABCA9

3.35e-041738544bc6d93716f093b460c8b047199db8cab5fea720
ToppCelldroplet-Mammary_Gland-nan-3m-Endothelial-nan|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MSR1 THRSP MICAL3 CLSTN1

3.35e-04173854fbc8ed566ea36c39c258dd6b3823c82f5d6eb17f
ToppCellPND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KIF23 POLH MAD1L1 ZNF521

3.43e-041748546c36d607c48267a75ab4da6fb2fe3f931d1b3b52
ToppCellfacs-Marrow-Granulocytes-3m-Myeloid-monocyte_+_promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MSR1 NIBAN2 PLXND1 ABCA9

3.50e-0417585469b59ec58e64644deb7e07f31ef495ef4a6f6276
ToppCellfacs-Marrow-Granulocytes-3m-Myeloid-promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MSR1 NIBAN2 PLXND1 ABCA9

3.50e-041758544f7498b5a0ed52c348a5f94bcd41d830ba7954ea
ToppCelldroplet-Heart-nan-3m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPM7 VPS13C CMYA5 ABCA9

3.58e-04176854749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCellprimary_visual_cortex-Non-neuronal|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

KANK1 LAMA2 CCDC141 ITPR2

3.58e-041768542c92f3f55d668cfe80051b5128160a6dc3aec4e8
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage-Monocyte-derived_macrophage_L.1.2.3.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DMXL2 PLXND1 COLGALT1 ITPR2

3.66e-04177854f28243b51be104cb3adcde63f03fc2206ed3121e
ToppCellfacs-Marrow-Granulocytes-18m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MSANTD3 KIF23 SYNE2 VCL

3.74e-0417885415a99080e9f669572ab6d82934f324e6714846c1
ToppCellfacs-Marrow-Granulocytes-18m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MSANTD3 KIF23 SYNE2 VCL

3.74e-04178854200308e109abb7e6f8816a6f8cce6d56862d4098
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

KANK1 TRPM7 CACHD1 ITPR1

3.82e-04179854666072c0e8448dbaec1683d18368ec2502453f90
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SUGCT SYNE2 HNF4A DHTKD1

3.90e-04180854f8bdfd7bf7b3d52c659a29d8f5f80858e79da83e
ToppCellCOPD-Lymphoid-T_Regulatory|World / Disease state, Lineage and Cell class

NCOA2 FCRL3 SYNE2 CCDC141

3.90e-0418085451a12fbad5fa7bb12e6d616a02ff9b5141e2b063
ToppCellRA-11._Adipocyte|RA / Chamber and Cluster_Paper

GABRE THRSP ACACA ITPR2

3.90e-04180854d48a3d27357f7d184132a6805950f93080146b59
ToppCellfacs-Lung-EPCAM-3m-Myeloid-Dendritic_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KANK1 MICAL3 DHTKD1 GMPPA

3.90e-04180854710526abedc8e0f9ba19ad69220df4c9468ada8f
ToppCell3'-GW_trimst-2-SmallIntestine-Hematopoietic-Red_blood_cells|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CARMIL2 POLH RTTN GRAP2

3.98e-04181854fe2f8b4bd8b09be8ba933529a16e1dca08740dab
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

KANK1 ACACA CACHD1 NIBAN2

3.98e-04181854576da14ab3107f89e1f44a4a439d1bef5bb42370
ToppCellfacs-Marrow-Granulocytes-3m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MSANTD3 KIF23 SYNE2 VCL

3.98e-04181854566249e04dd491e6287ad2101b7b1ab11031ed8b
ToppCellRV|World / Chamber and Cluster_Paper

TRPM7 MICAL3 CMYA5 CCDC141

3.98e-04181854bbe1e6e59d8889bd37d6e8303116cbdcafca7236
ToppCellfacs-Marrow-Granulocytes-3m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MSANTD3 KIF23 SYNE2 VCL

3.98e-04181854db9528dc7cb0230e4c36cb27da69102c588c7ee9
ToppCell3'-GW_trimst-2-SmallIntestine-Hematopoietic-Red_blood_cells-RBC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CARMIL2 POLH RTTN GRAP2

3.98e-04181854a16079b1c832456b974d9d06dd1a3eda63ac1bce
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SUGCT SLC13A2 HNF4A ADCY8

4.06e-04182854e1e58176f533092b6b974ca1ce8b02192a6e193d
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

HIVEP2 CARMIL2 SYNE2 VIRMA

4.06e-041828541aea96ee211f7b9caef7fd385233f51be6021a73
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SUGCT SLC13A2 HNF4A ADCY8

4.06e-041828544a9c13932e7163fd37a3dcc4c6ca3bbea5372459
ToppCelldroplet-Marrow-nan-3m-Myeloid-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MSR1 VPS13C KAT6A ABCA9

4.06e-04182854f8c73baaaca145e2efc48f10f636feb79c8fc779
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

HIVEP2 CARMIL2 SYNE2 VIRMA

4.06e-04182854b427e43ee523a3ea9eca3207f3d82042f10f022a
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

HIVEP2 CARMIL2 SYNE2 VIRMA

4.06e-04182854c0f63cfc67d61c0877b7acb2946dfb35aae8a8f5
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SUGCT SLC13A2 HNF4A ADCY8

4.06e-0418285457bb5a2da976464ba7c4460106bd9f692008ebd9
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

HIVEP2 CARMIL2 SYNE2 VIRMA

4.06e-041828544cb182ef39be2044a6ad7266f332d4177591e550
ToppCellURO-Lymphocyte-T_NK-dnT|URO / Disease, Lineage and Cell Type

RPTOR SYNE2 MICAL3 ZNF461

4.06e-04182854f2b1c524301d0f2d1b69c46f3653fd53c21c3aa0
ToppCell343B-Lymphocytic-CD4_T-cell-Treg_cell_1|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

GPHN YLPM1 CLSTN1 TRRAP

4.15e-04183854807d64deaf4e50dccf6f831f88578a6d903c1421
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KANK1 TRPM7 CACHD1 ITPR1

4.15e-041838542f0ee40e69ad1259e56e8ee4b352736900eb8901
DiseaseAnoxic Encephalopathy

ITPR1 ITPR2

7.44e-062812C0003132
DiseaseBrain Hypoxia

ITPR1 ITPR2

7.44e-062812C1527348
DiseaseAnoxia of brain

ITPR1 ITPR2

7.44e-062812C0995195
DiseaseHypoxic Brain Damage

ITPR1 ITPR2

7.44e-062812C1140716
Diseaseselenium measurement

SDCCAG8 ZNF521 CMYA5

6.92e-0529813EFO_0006331
DiseaseCongenital muscular dystrophy (disorder)

SYNE2 LAMA2

1.11e-046812C0699743
Diseasebipolar disorder, schizophrenia, schizoaffective disorder

SDCCAG8 MAD1L1

1.11e-046812EFO_0005411, MONDO_0004985, MONDO_0005090
Diseasevanillylmandelate (VMA) measurement

UGT2B15 DBH

1.55e-047812EFO_0800119
DiseaseIGF-1 measurement

MSR1 ZNF12 SALL1 STARD9 VPS13C SYNE2 UGT2B15

3.93e-04488817EFO_0004627
Diseasehematocrit

PLSCR4 ZNF12 HIVEP2 SALL1 ACACA SUGCT HNF4A TTC33 ITPR1 ITPR2

4.43e-0410118110EFO_0004348
DiseaseC-reactive protein measurement

DMXL2 ZNF276 SALL1 SETD5 VPS13C MICAL3 CEP192 CACHD1 HNF4A ADCY8 ITPR1

4.48e-0412068111EFO_0004458
Diseaseautosomal dominant cerebellar ataxia (implicated_via_orthology)

ITPR1 ITPR2

4.83e-0412812DOID:1441 (implicated_via_orthology)
Diseasecognitive function measurement

NCOA2 DMXL2 GBF1 ARHGEF10 SDCCAG8 MAD1L1 GATB ZNF521 UGT2B15 CEP192 GMPPA REV1

5.24e-0414348112EFO_0008354
Diseaseattention function measurement

MSR1 NCOA2 ADCY8 ITPR1

7.49e-04148814EFO_0007636
DiseaseProstate cancer, familial

MSR1 SUGCT MAD1L1

9.16e-0469813C2931456
DiseaseTesticular Germ Cell Tumor

SUGCT MAD1L1 CLSTN1

1.08e-0373813EFO_1000566
DiseaseDiGeorge syndrome (implicated_via_orthology)

KAT6A PLXND1

1.23e-0319812DOID:11198 (implicated_via_orthology)
Diseaseage at onset, smoking initiation

NCOA2 ITPR2

1.23e-0319812EFO_0004847, EFO_0005670
Diseasemultiple sclerosis

NCOA2 FCRL3 ARHGEF10 GRAP2 ADCY8 TTC33 ITPR1

1.24e-03594817MONDO_0005301
DiseaseIntellectual Disability

HIVEP2 SDCCAG8 RTTN LAMA1 TRRAP CERT1

1.46e-03447816C3714756
DiseaseHeadache, HbA1c measurement

MAD1L1 PLXND1

1.51e-0321812EFO_0004541, HP_0002315
Diseasemental or behavioural disorder

VPS13C MAD1L1 CMYA5 TTC33

1.51e-03179814EFO_0000677
Diseaseunipolar depression

NCOA2 GPHN HIVEP2 ARHGEF10 SYNE2 MAD1L1 YLPM1 C16orf78 AK9 ITPR2

1.69e-0312068110EFO_0003761
DiseaseOvarian Serous Adenocarcinoma

TRPM7 TRRAP

1.81e-0323812C1335177
DiseaseFEV/FEC ratio

KANK1 HIVEP2 VPS13C SYNE2 YLPM1 MICAL3 DBH TFAP2C ADCY8 ITPR1

1.93e-0312288110EFO_0004713
Diseasesuicidal ideation, suicide behaviour

MAD1L1 GATB

1.98e-0324812EFO_0004320, EFO_0007623
DiseaseUterine leiomyoma

KANK1 ITPR1 REV1

2.03e-0391813HP_0000131
Diseaselymphocyte count

PLSCR4 MSR1 NCOA2 GBF1 CARMIL2 ACACA MICAL3 PLXND1 CLSTN1 ITPR1 ITPR2

2.15e-0314648111EFO_0004587
DiseaseNeurodevelopmental Disorders

SETD5 CERT1 ITPR1

2.16e-0393813C1535926
Diseaseuterine fibroid

NCOA2 KANK1 ITPR1 REV1

2.23e-03199814EFO_0000731
Diseasediet measurement, bilirubin measurement

LAMA2 CACHD1

2.32e-0326812EFO_0004570, EFO_0008111
Diseasestimulant use measurement

NCOA2 ADCY8

2.69e-0328812EFO_0600076
Diseasegastroesophageal reflux disease

HIVEP2 MAD1L1 YLPM1

2.74e-03101813EFO_0003948

Protein segments in the cluster

PeptideGeneStartEntry
VLHNGLVMEMEHPTV

SUGCT

371

Q9HAC7
AEIHLIRDMMDPNHT

ALS2CL

901

Q60I27
MINDMTNVEDEHLQH

ADCY8

386

P40145
QLEAHQEEGMVISHM

ARHGEF10

1101

O15013
GLHDMPHQMDEVQNV

TFAP2C

166

Q92754
ISHQSVEPVVMMHMN

BAG6

446

P46379
LHQVHDTPQMSSMDL

ABCA9

51

Q8IUA7
QILHMMSQSSHLEEL

CARMIL2

236

Q6F5E8
HQHMSPLAAQEMSVR

CACHD1

1126

Q5VU97
AGMNVDIHPHMVEED

C16orf78

236

Q8WTQ4
NPEVAMDSIIHMTQH

ACACA

2311

Q13085
HSVMEAHPQVVMDVK

GATB

506

O75879
HAELMPDQTAMHEVQ

DMXL2

331

Q8TDJ6
NVIHTANPMEHANHM

CLSTN1

811

O94985
MKSVEVPRELQMHSH

DHTKD1

536

Q96HY7
LDTPVMVHMDHVSAV

DCAF13

271

Q9NV06
TLLTNMTVTNDHQHM

ARMC10

201

Q8N2F6
EQLNHHTTTRTQMEM

RAD50

526

Q92878
MATEGMILTNHDHQI

GPHN

1

Q9NQX3
LMLHMHVDRDPQESV

ITPR2

781

Q14571
RDSMVMHNSDPNLHL

NIBAN2

566

Q96TA1
HRFSSQVEEMVQNHM

CERT1

391

Q9Y5P4
MDANLCQVIHMELDH

MAPK9

111

P45984
AMERVCMHPHNVLSD

DCAF1

426

Q9Y4B6
MEERKHETMNPAHVL

MICAL3

1

Q7RTP6
MVQKVHSHSAEMEAQ

MAD1L1

441

Q9Y6D9
NEVRLHMMCATHPNI

MAPKAPK5

61

Q8IW41
HMMCATHPNIVQIIE

MAPKAPK5

66

Q8IW41
MLHMHVDRDPQEQVT

ITPR1

786

Q14643
PHLMQEHMGTNVIVA

HNF4A

391

P41235
NEHIHMDNLAQMPMI

PLPPR5

281

Q32ZL2
NIHVLQHFEPLEMMT

PLSCR4

121

Q9NRQ2
MVQNVSMAVHHIGRE

PLXND1

1096

Q9Y4D7
SPMHLQHIREQMAIA

KANK1

256

Q14678
KRTHEHEITMPNQMV

GABRE

161

P78334
VFQHPEIVAHMDLMR

LAMA2

1211

P24043
MHEEEHHQQMSILQL

MSANTD3

196

Q96H12
QHILDMEANLMDTEH

MSR1

126

P21757
PQMSMVEDCHASEHN

KAT6A

1466

Q92794
MIQHHIEACAQVPGM

GMPPA

36

Q96IJ6
ESMMSEVHERALQQH

CCDC141

1321

Q6ZP82
VSLHHHMQVMEEVVR

GUSB

421

P08236
LHEQMVHFLQSMDTA

CMYA5

3621

Q8N3K9
VHHMEVFQCAPEMDS

DBH

261

P09172
NEPDHHDFDNVSMTM

IDUA

181

P35475
ANCPMMHQEHEELTV

FCRL3

676

Q96P31
SVADMQNMPAAVHAL

CEP192

1236

Q8TEP8
NPHDRHNSEVMIHMG

GBF1

416

Q92538
SMPVHAAVQMTTEQL

HLTF

196

Q14527
ESFMHVQLEVMVKHP

COLGALT1

306

Q8NBJ5
EMNAALMHRRHTDPV

GRAP2

251

O75791
AMMVPIAHAVLDQLH

SLC13A2

146

Q13183
TNAVVLQQHIRMHMG

SALL1

776

Q9NSC2
SNMQTETVMQPHVPH

KIF23

826

Q02241
QPEVMLVHHRMAFIS

RTTN

461

Q86VV8
MQMVAEILHHLVQRP

AK9

216

Q5TCS8
MMLQEKHSEDQHPTI

SYNE2

4331

Q8WXH0
NQMVMESDILQEDHH

RIF1

2101

Q5UIP0
EHEETNMPTMHDLVH

SDCCAG8

106

Q86SQ7
NMPTMHDLVHTINDQ

SDCCAG8

111

Q86SQ7
HIDDLVMHMSQRNAV

LAMA1

1851

P25391
PNAEVRHMIADGMIH

SETD5

356

Q9C0A6
TPAEMDLAHNSQSMH

POLH

591

Q9Y253
QMCMAPEHQHHSLRD

STARD9

4121

Q9P2P6
HSTTIDHNVAMMLAQ

RPTOR

636

Q8N122
EQVTVHVPMMHQKEQ

SERPINA9

231

Q86WD7
HMLHREQNVCVMNPD

NCOA2

371

Q15596
RIMIDDHNVPTLHQM

TPTE

301

P56180
NSPRHQSCIMHVDMD

REV1

411

Q9UBZ9
RDHLPQLTEHMTDMT

TBC1D8B

626

Q0IIM8
VEETSLMNHMEQVHS

ZNF521

291

Q96K83
HLNPMQLMTVDASHA

SAP130

541

Q9H0E3
ELTHQEHRVMLVNSM

VCL

181

P18206
VHMSMVHPLTQTQDK

ZNF276

571

Q8N554
STMHILQPMDIHVEL

VPS13C

776

Q709C8
PPHIQTMSVDMQLRH

YLPM1

426

P49750
QMIIRHEEMPTFDQH

ZNF582

141

Q96NG8
LREVSVMMNLEHPHV

TNK1

166

Q13470
LQMSDLTVHQTSHME

ZNF12

251

P17014
ENVMKLSRIHHDQPM

UGT2B15

441

P54855
LHLAQPQIMHMDSQE

HIVEP2

1151

P31629
AAEVHNMEQVVMIPS

THRSP

21

Q92748
HLMETAPHTMIQQPV

VIRMA

636

Q69YN4
PVRHHLVQHMVSAMQ

TRRAP

1976

Q9Y4A5
EMSHIPQSQDAHQMT

TRPM7

781

Q96QT4
MINHENMPIFSQHTL

ZNF461

166

Q8TAF7
QVLMSLHEMFPAVHA

TTC33

101

Q6PID6
LHEMFPAVHAAEMAV

TTC33

106

Q6PID6