Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionRNA polymerase II transcription regulatory region sequence-specific DNA binding

ZNF502 ZNF16 ZNF134 ZNF773 USF3 ZNF143 ZNF497 ZFP3 ZNF852 ZSCAN26 ZNF75D ZNF322 ZNF880 ZNF83 ZNF679 ZNF454 ZNF850 ZNF582 MNT ZFY MEOX2

2.48e-0814597221GO:0000977
GeneOntologyMolecularFunctionRNA polymerase II cis-regulatory region sequence-specific DNA binding

ZNF502 ZNF16 ZNF134 ZNF773 ZNF143 ZNF497 ZFP3 ZNF852 ZSCAN26 ZNF75D ZNF322 ZNF880 ZNF83 ZNF679 ZNF454 ZNF850 MNT ZFY MEOX2

5.38e-0812447219GO:0000978
GeneOntologyMolecularFunctioncis-regulatory region sequence-specific DNA binding

ZNF502 ZNF16 ZNF134 ZNF773 ZNF143 ZNF497 ZFP3 ZNF852 ZSCAN26 ZNF75D ZNF322 ZNF880 ZNF83 ZNF679 ZNF454 ZNF850 MNT ZFY MEOX2

7.56e-0812717219GO:0000987
GeneOntologyMolecularFunctionDNA-binding transcription factor activity, RNA polymerase II-specific

ZNF502 ZNF16 ZNF134 ZNF773 USF3 ZNF143 ZFP3 ZNF852 ZSCAN26 ZNF75D ZNF322 ZNF880 ZNF83 ZNF679 ZNF454 ZNF850 ZNF582 MNT ZFY MEOX2

7.62e-0814127220GO:0000981
GeneOntologyMolecularFunctionpeptidyltransferase activity

GGT2P GGT1

1.91e-046722GO:0000048
GeneOntologyMolecularFunctionleukotriene-C(4) hydrolase

GGT2P GGT1

1.91e-046722GO:0002951
GeneOntologyMolecularFunctionleukotriene C4 gamma-glutamyl transferase activity

GGT2P GGT1

3.54e-048722GO:0103068
GeneOntologyMolecularFunctionglutathione hydrolase activity

GGT2P GGT1

4.54e-049722GO:0036374
GeneOntologyMolecularFunctiondynactin binding

SPTBN5 HTT

8.27e-0412722GO:0034452
GeneOntologyMolecularFunctionomega peptidase activity

GGT2P GGT1

1.49e-0316722GO:0008242
GeneOntologyMolecularFunctionthreonine-type peptidase activity

GGT2P GGT1

2.34e-0320722GO:0070003
HumanPhenoAplasia/Hypoplasia of the distal phalanx of the 5th toe

ARID1B KCNN3

1.62e-052212HP:0100371
HumanPhenoAbnormality of the distal phalanx of the 5th toe

ARID1B KCNN3

1.62e-052212HP:0010392
MousePhenoabnormal circulating glutathione level

GGT2P GGT1

1.01e-045452MP:0030652
MousePhenoincreased circulating glutathione level

GGT2P GGT1

1.01e-045452MP:0030653
MousePhenoincreased glutathione level

GGT2P GGT1

1.01e-045452MP:0012606
MousePhenoglutathionuria

GGT2P GGT1

1.01e-045452MP:0013730
DomainZINC_FINGER_C2H2_2

ZNF502 ZNF16 ZNF134 ZNF773 ZNF143 ZNF497 ZFP3 ZNF852 ZNF804B ZSCAN26 ZNF75D ZNF322 ZNF880 ZNF83 GPATCH8 ZNF679 ZNF454 ZNF850 ZNF804A ZNF582 ZFY

2.99e-137756921PS50157
DomainZINC_FINGER_C2H2_1

ZNF502 ZNF16 ZNF134 ZNF773 ZNF143 ZNF497 ZFP3 ZNF852 ZNF804B ZSCAN26 ZNF75D ZNF322 ZNF880 ZNF83 GPATCH8 ZNF679 ZNF454 ZNF850 ZNF804A ZNF582 ZFY

3.14e-137776921PS00028
DomainZnf_C2H2-like

ZNF502 ZNF16 ZNF134 ZNF773 ZNF143 ZNF497 ZFP3 ZNF852 ZNF804B ZSCAN26 ZNF75D ZNF322 ZNF880 ZNF83 GPATCH8 ZNF679 ZNF454 ZNF850 ZNF804A ZNF582 ZFY

5.01e-137966921IPR015880
DomainZnf_C2H2

ZNF502 ZNF16 ZNF134 ZNF773 ZNF143 ZNF497 ZFP3 ZNF852 ZNF804B ZSCAN26 ZNF75D ZNF322 ZNF880 ZNF83 GPATCH8 ZNF679 ZNF454 ZNF850 ZNF804A ZNF582 ZFY

6.21e-138056921IPR007087
DomainZnF_C2H2

ZNF502 ZNF16 ZNF134 ZNF773 ZNF143 ZNF497 ZFP3 ZNF852 ZNF804B ZSCAN26 ZNF75D ZNF322 ZNF880 ZNF83 GPATCH8 ZNF679 ZNF454 ZNF850 ZNF804A ZNF582 ZFY

6.67e-138086921SM00355
Domain-

ZNF502 ZNF16 ZNF134 ZNF773 ZNF143 ZNF497 ZFP3 ZNF852 ZSCAN26 ZNF75D ZNF322 ZNF880 ZNF83 ZNF679 ZNF454 ZNF850 ZNF582 ZFY

2.99e-1167969183.30.160.60
Domainzf-C2H2

ZNF502 ZNF16 ZNF134 ZNF773 ZNF143 ZNF497 ZFP3 ZNF852 ZSCAN26 ZNF75D ZNF322 ZNF880 ZNF83 ZNF679 ZNF454 ZNF850 ZNF582 ZFY

4.18e-116936918PF00096
DomainZnf_C2H2/integrase_DNA-bd

ZNF502 ZNF16 ZNF134 ZNF773 ZNF143 ZNF497 ZFP3 ZNF852 ZSCAN26 ZNF75D ZNF322 ZNF880 ZNF83 ZNF679 ZNF454 ZNF850 ZNF582 ZFY

4.28e-116946918IPR013087
DomainTMEM176A/TMEM176B

TMEM176B TMEM176A

1.35e-052692IPR009281
Domainzf-C2H2_6

ZNF502 ZNF16 ZNF773 ZNF497 ZNF852 ZNF880 ZNF850 ZNF582

2.00e-05314698PF13912
DomainKRAB

ZNF773 ZNF852 ZNF75D ZNF880 ZNF679 ZNF454 ZNF850 ZNF582

5.09e-05358698PS50805
DomainKRAB

ZNF773 ZNF852 ZNF75D ZNF880 ZNF679 ZNF454 ZNF850 ZNF582

5.09e-05358698PF01352
DomainKRAB

ZNF773 ZNF852 ZNF75D ZNF880 ZNF679 ZNF454 ZNF850 ZNF582

6.29e-05369698SM00349
DomainKRAB

ZNF773 ZNF852 ZNF75D ZNF880 ZNF679 ZNF454 ZNF850 ZNF582

6.41e-05370698IPR001909
DomainZnf_C2H2_jaz

ZNF804B GPATCH8 ZNF804A

7.07e-0522693IPR022755
Domainzf-C2H2_jaz

ZNF804B GPATCH8 ZNF804A

7.07e-0522693PF12171
DomainCD20-like

TMEM176B TMEM176A

2.96e-0322692IPR007237
DomainCD20

TMEM176B TMEM176A

2.96e-0322692PF04103
DomainLRR_8

LRTM1 SLITRK3 LRRD1 LRCH3

3.69e-03171694PF13855
DomainLeu-rich_rpt_typical-subtyp

LRTM1 SLITRK3 LRRD1 LRCH3

4.17e-03177694IPR003591
DomainLRR_TYP

LRTM1 SLITRK3 LRRD1 LRCH3

4.17e-03177694SM00369
Domain-

PAPPA2 CELSR1 AGRN

5.24e-03956932.60.120.200
DomainEGF_LAM_2

CELSR1 AGRN

5.47e-0330692PS50027
DomainEGF_LAM_1

CELSR1 AGRN

5.47e-0330692PS01248
DomainLaminin_EGF

CELSR1 AGRN

7.40e-0335692PF00053
DomainEGF_Lam

CELSR1 AGRN

7.40e-0335692SM00180
DomainLAM_G_DOMAIN

CELSR1 AGRN

8.68e-0338692PS50025
DomainLaminin_EGF

CELSR1 AGRN

8.68e-0338692IPR002049
DomainLRR_1

LRTM1 SLITRK3 LRRD1 LRCH3

8.78e-03219694PF00560
PathwayREACTOME_RNA_POLYMERASE_II_TRANSCRIPTION

KMT2C ARID1B ZNF773 ZNF143 CAMK2G ZNF804B AUTS2 ZNF75D MAML2 ZNF679 ZNF454 ZNF582 HTT

2.85e-0513873713M734
Pubmed

The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.

ZNF502 USP34 ZNF16 ARID1B ZNF773 ZNF143 WASHC4 ATN1 ATXN2 RBM27 CAMK2G ZSCAN26 ATL3 AUTS2 ZNF322 GPATCH8 ZNF850 MNT AQR

5.33e-121203741929180619
Pubmed

Cloning of the gene for spinocerebellar ataxia 2 reveals a locus with high sensitivity to expanded CAG/glutamine repeats.

ARID1B ATXN2 KCNN3

1.84e-0767438896557
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

USP34 KMT2C ARID1B WASHC4 RBM27 AUTS2 CACHD1 MAML2 ADCY9

1.87e-0652974914621295
Pubmed

Tmem176B and Tmem176A are associated with the immature state of dendritic cells.

TMEM176B TMEM176A

4.47e-06274220501748
Pubmed

Abnormal accumulation of human transmembrane (TMEM)-176A and 176B proteins is associated with cancer pathology.

TMEM176B TMEM176A

4.47e-06274222244448
Pubmed

Clinical application value of hepatitis B virus basal core promoter 1762/1764 and GGTII and GGT in patients with HBV-DNA-positive primary liver cancer.

GGT2P GGT1

4.47e-06274237904480
Pubmed

Gamma glutamyl transferase activity is independently associated with oxidative stress rather than SYNTAX score.

GGT2P GGT1

4.47e-06274225180444
Pubmed

Distinct behavioral and neuropathological abnormalities in transgenic mouse models of HD and DRPLA.

ATN1 HTT

4.47e-06274211442350
Pubmed

Human GGT2 does not autocleave into a functional enzyme: A cautionary tale for interpretation of microarray data on redox signaling.

GGT2P GGT1

4.47e-06274223682772
Pubmed

TMEM176A and TMEM176B Are Candidate Regulators of Inhibition of Dendritic Cell Maturation and Function after Chronic Spinal Cord Injury.

TMEM176B TMEM176A

4.47e-06274231354034
Pubmed

Gene expression profile of renal proximal tubules regulated by proteinuria.

TMEM176B TMEM176A

4.47e-06274211967007
Pubmed

Generation of a Double KO Mouse by Simultaneous Targeting of the Neighboring Genes Tmem176a and Tmem176b Using CRISPR/Cas9: Key Steps from Design to Genotyping.

TMEM176B TMEM176A

4.47e-06274227234594
Pubmed

Association between serum γ-glutamyltranspeptidase and atherosclerosis: a population-based cross-sectional study.

GGT2P GGT1

4.47e-06274225280803
Pubmed

Comparative Application of BioID and TurboID for Protein-Proximity Biotinylation.

USP34 KMT2C ARID1B ATN1 ATXN2 RBM27 AUTS2 GPATCH8

5.90e-0645774832344865
Pubmed

Dendritic Cells Require TMEM176A/B Ion Channels for Optimal MHC Class II Antigen Presentation to Naive CD4+ T Cells.

TMEM176B TMEM176A

1.34e-05374234233909
Pubmed

Different gamma-glutamyl transpeptidase mRNAs are expressed in human liver and kidney.

GGT2P GGT1

1.34e-0537422573352
Pubmed

dAtaxin-2 mediates expanded Ataxin-1-induced neurodegeneration in a Drosophila model of SCA1.

ATXN2 HTT

1.34e-05374218166084
Pubmed

The Repeat Expansion Diseases: The dark side of DNA repair.

ATN1 ATXN2 HTT

1.59e-052374326002199
Pubmed

RORγt+ cells selectively express redundant cation channels linked to the Golgi apparatus.

TMEM176B TMEM176A

2.67e-05474227009467
Pubmed

Is the 31 CAG repeat allele of the spinocerebellar ataxia 1 (SCA1) gene locus non-specifically associated with trinucleotide expansion diseases?

ATN1 HTT

2.67e-05474211807410
Pubmed

Expanded CAG Repeats in ATXN1, ATXN2, ATXN3, and HTT in the 1000 Genomes Project.

ATXN2 HTT

2.67e-05474233159825
Pubmed

Searching for mutation in the JPH3, ATN1 and TBP genes in Polish patients suspected of Huntington's disease and without mutation in the IT15 gene.

ATN1 HTT

2.67e-05474218651325
Pubmed

Zfx controls the self-renewal of embryonic and hematopoietic stem cells.

ZFY MEOX2

2.67e-05474217448993
Pubmed

Lung lining fluid glutathione attenuates IL-13-induced asthma.

GGT2P GGT1

4.45e-05574218063838
Pubmed

Gamma-glutamyltranspeptidase knockout mice as a model for understanding the consequences of diminished glutathione on T cell-dependent immune responses.

GGT2P GGT1

4.45e-05574210940879
Pubmed

Liver-Specific Overexpression of Gamma-Glutamyltransferase Ameliorates Insulin Sensitivity of Male C57BL/6 Mice.

GGT2P GGT1

4.45e-05574228660214
Pubmed

Bleomycin-induced pulmonary fibrosis is attenuated in gamma-glutamyl transpeptidase-deficient mice.

GGT2P GGT1

4.45e-05574212468440
Pubmed

N-acetyl-cysteine prevents age-related hearing loss and the progressive loss of inner hair cells in γ-glutamyl transferase 1 deficient mice.

GGT2P GGT1

4.45e-05574226977590
Pubmed

Gamma-glutamyl transferase deficiency results in lung oxidant stress in normoxia.

GGT2P GGT1

4.45e-05574212225953
Pubmed

Identification of a sixth promoter that directs the transcription of gamma-glutamyl transpeptidase type III RNA in mouse.

GGT2P GGT1

4.45e-0557427775425
Pubmed

Cataract development in gamma-glutamyl transpeptidase-deficient mice.

GGT2P GGT1

4.45e-05574211095909
Pubmed

Expression of gamma-glutamyl transpeptidase in midgestation mouse yolk sac and mouse visceral yolk sac carcinoma cells.

GGT2P GGT1

4.45e-0557427641802
Pubmed

Phenotypic characterization of Ggt1(dwg/dwg) mice,a mouse model for hereditary γ-glutamyltransferase deficiency.

GGT2P GGT1

4.45e-05574223615310
Pubmed

Cloning of cDNA and genomic structure of the mouse gamma-glutamyl transpeptidase-encoding gene.

GGT2P GGT1

4.45e-0557428566783
Pubmed

Therapeutic Effect of GGsTop, Selective Gamma-glutamyl Transpeptidase Inhibitor, on a Mouse Model of 5-Fluorouracil-induced Oral Mucositis.

GGT2P GGT1

4.45e-05574230591459
Pubmed

Mice with genetic gamma-glutamyl transpeptidase deficiency exhibit glutathionuria, severe growth failure, reduced life spans, and infertility.

GGT2P GGT1

4.45e-0557429139708
Pubmed

Analysis of site-specific glycosylation of renal and hepatic γ-glutamyl transpeptidase from normal human tissue.

GGT2P GGT1

4.45e-05574220622017
Pubmed

The mouse skin carcinogenesis model.

GGT2P GGT1

4.45e-0557429627710
Pubmed

Accelerated methylmercury elimination in gamma-glutamyl transpeptidase-deficient mice.

GGT2P GGT1

4.45e-0557429546365
Pubmed

Gamma-glutamyl transpeptidase and its role in melanogenesis: redox reactions and regulation of tyrosinase.

GGT2P GGT1

4.45e-05574212453183
Pubmed

In vivo reversal of glutathione deficiency and susceptibility to in vivo dexamethasone-induced apoptosis by N-acetylcysteine and L-2-oxothiazolidine-4-carboxylic acid, but not ascorbic acid, in thymocytes from gamma-glutamyltranspeptidase-deficient knockout mice.

GGT2P GGT1

4.45e-05574211795900
Pubmed

gamma-Glutamyl transpeptidase. What does the organization and expression of a multipromoter gene tell us about its functions?

GGT2P GGT1

4.45e-0557427485380
Pubmed

gamma-glutamyltranspeptidase-deficient knockout mice as a model to study the relationship between glutathione status, mitochondrial function, and cellular function.

GGT2P GGT1

4.45e-05574211003618
Pubmed

Accumulation of DNA damage in the organs of mice deficient in gamma-glutamyltranspeptidase.

GGT2P GGT1

4.45e-05574210751614
Pubmed

Gamma-glutamyl transpeptidase gene organization and expression: a comparative analysis in rat, mouse, pig and human species.

GGT2P GGT1

4.45e-05574210392451
Pubmed

Type VI RNA is the major gamma-glutamyl transpeptidase RNA in the mouse small intestine.

GGT2P GGT1

4.45e-0557427523374
Pubmed

Immunocytochemical localization of gamma-glutamyltranspeptidase during fetal development of mouse kidney.

GGT2P GGT1

4.45e-0557422891746
Pubmed

Cardio-reno-hepatic interactions in acute heart failure: the role of γ-glutamyl transferase.

GGT2P GGT1

4.45e-05574224698228
Pubmed

Hyperoxia-induced lung injury in gamma-glutamyl transferase deficiency is associated with alterations in nitrosative and nitrative stress.

GGT2P GGT1

4.45e-05574219850887
Pubmed

Inhibiting lung lining fluid glutathione metabolism with GGsTop as a novel treatment for asthma.

GGT2P GGT1

4.45e-05574225132819
Pubmed

Characterization of the dwg mutations: dwg and dwg(Bayer) are new mutant alleles of the Ggt1 gene.

GGT2P GGT1

4.45e-05574219760322
Pubmed

gamma-Glutamyl transferase (GGT) deficiency in the GGTenu1 mouse results from a single point mutation that leads to a stop codon in the first coding exon of GGT mRNA.

GGT2P GGT1

4.45e-05574210474818
Pubmed

Reversible skeletal abnormalities in gamma-glutamyl transpeptidase-deficient mice.

GGT2P GGT1

4.45e-05574212810527
Pubmed

Growth retardation and cysteine deficiency in gamma-glutamyl transpeptidase-deficient mice.

GGT2P GGT1

4.45e-0557428755578
Pubmed

Reproductive defects in gamma-glutamyl transpeptidase-deficient mice.

GGT2P GGT1

4.45e-05574211089562
Pubmed

Molecular analysis of CAG repeats at five different spinocerebellar ataxia loci: correlation and alternative explanations for disease pathogenesis.

ATN1 ATXN2

4.45e-05574218182848
Pubmed

The PcG protein hPc2 interacts with the N-terminus of histone demethylase JARID1B and acts as a transcriptional co-repressor.

ARID1B SLITRK3 MEOX2

4.82e-053374319336002
Pubmed

Deletion mapping by immunoselection against the H-Y histocompatibility antigen further resolves the Sxra region of the mouse Y chromosome and reveals complexity of the Hya locus.

AMELY ZFY

6.66e-0567427896271
Pubmed

Gamma-glutamyl leukotrienase, a novel endothelial membrane protein, is specifically responsible for leukotriene D(4) formation in vivo.

GGT2P GGT1

6.66e-05674212163373
Pubmed

Gamma-glutamyltranspeptidase stimulates receptor activator of nuclear factor-kappaB ligand expression independent of its enzymatic activity and serves as a pathological bone-resorbing factor.

GGT2P GGT1

6.66e-05674214634009
Pubmed

Overexpression of gamma-glutamyltransferase in transgenic mice accelerates bone resorption and causes osteoporosis.

GGT2P GGT1

6.66e-05674217363454
Pubmed

Six mRNAs with different 5' ends are encoded by a single gamma-glutamyltransferase gene in mouse.

GGT2P GGT1

6.66e-0567428101000
Pubmed

Four distinct membrane-bound dipeptidase RNAs are differentially expressed and show discordant regulation with gamma-glutamyl transpeptidase.

GGT2P GGT1

6.66e-0567428663190
Pubmed

Polyglutamine tracts regulate beclin 1-dependent autophagy.

ATN1 HTT

6.66e-05674228445460
Pubmed

Mapping of human gamma-glutamyl transpeptidase genes on chromosome 22 and other human autosomes.

GGT2P GGT1

6.66e-0567428104871
Pubmed

Disruption of gamma-glutamyl leukotrienase results in disruption of leukotriene D(4) synthesis in vivo and attenuation of the acute inflammatory response.

GGT2P GGT1

6.66e-05674211463821
Pubmed

Ablation of Mrds1/Ofcc1 induces hyper-γ-glutamyl transpeptidasemia without abnormal head development and schizophrenia-relevant behaviors in mice.

GGT2P GGT1

6.66e-05674222242126
Pubmed

Effect of atorvastatin on the expression of gamma-glutamyl transferase in aortic atherosclerotic plaques of apolipoprotein E-knockout mice.

GGT2P GGT1

6.66e-05674225326709
Pubmed

Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

USP34 GPATCH8 ADCY9 AQR

7.67e-051057449628581
Pubmed

γ-Glutamyltranspeptidase is an endogenous activator of Toll-like receptor 4-mediated osteoclastogenesis.

GGT2P GGT1

9.31e-05774227775020
Pubmed

Genetic testing in spinocerebellar ataxia in Taiwan: expansions of trinucleotide repeats in SCA8 and SCA17 are associated with typical Parkinson's disease.

ATN1 ATXN2

9.31e-05774214756671
Pubmed

Defective epidermal growth factor gene expression in mice with polycystic kidney disease.

GGT2P GGT1

9.31e-0577421968405
Pubmed

The ins and outs of a polyglutamine neurodegenerative disease: spinocerebellar ataxia type 1 (SCA1).

ATXN2 HTT

9.31e-05774210860780
Pubmed

Comparison of the number of triplets in SCA1, MJD/SCA3, HD, SBMA, DRPLA, MD, FRAXA and FRDA genes in schizophrenic patients and a healthy population.

ATN1 HTT

9.31e-05774211121205
Pubmed

Transcriptional profiling and therapeutic targeting of oxidative stress in neuroinflammation.

GGT2P GGT1

9.31e-05774232284594
Pubmed

m6A eraser FTO modulates autophagy by targeting SQSTM1/P62 in the prevention of canagliflozin against renal fibrosis.

GGT2P GGT1

9.31e-05774236685533
Pubmed

Ataxin-2 and huntingtin interact with endophilin-A complexes to function in plastin-associated pathways.

ATXN2 HTT

1.24e-04874216115810
Pubmed

Caspase cleavage of gene products associated with triplet expansion disorders generates truncated fragments containing the polyglutamine tract.

ATN1 HTT

1.59e-0497429535906
Pubmed

Genome-wide interrogation of germline genetic variation associated with treatment response in childhood acute lymphoblastic leukemia.

ARID1B MAML2

1.59e-04974219176441
Pubmed

Dlx and other homeobox genes in the morphological development of the dentition.

AMELY MEOX2

1.99e-04107427554933
Pubmed

Distal-less and other homeobox genes in the development of the dentition.

AMELY MEOX2

1.99e-04107427964557
Pubmed

Screening for premutation in the FMR1 gene in male patients suspected of spinocerebellar ataxia.

ATN1 ATXN2

1.99e-041074219235102
Pubmed

Renalase regulates renal dopamine and phosphate metabolism.

GGT2P GGT1

1.99e-041074223863468
Pubmed

Apocrine glands are bystanders in hidradenitis suppurativa and their involvement is gender specific.

TMEM41A RBM27 ZNF804B

2.76e-045974332031713
Pubmed

Zinc finger protein genes in the mouse genome.

ZFP3 ZFY

2.91e-04127421797234
Pubmed

Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.

USF3 ATN1 ATXN2 XIRP2 MAML2 ZNF804A

3.14e-0443074635044719
Pubmed

The human gamma-glutamyltransferase gene family.

GGT2P GGT1

4.00e-041474218357469
Pubmed

Molecular genetics of hereditary spinocerebellar ataxia: mutation analysis of spinocerebellar ataxia genes and CAG/CTG repeat expansion detection in 225 Italian families.

ATN1 ATXN2

5.95e-041774215148151
Pubmed

Isolation and fine mapping of 16 novel human zinc finger-encoding cDNAs identify putative candidate genes for developmental and malignant disorders.

ZNF134 ZNF143

5.95e-04177427557990
Pubmed

Transcriptome-based systematic identification of extracellular matrix proteins.

AMELY AGRN EMILIN1

6.51e-047974318757743
Pubmed

Gene dosage in the developing and adult brain in a mouse model of 22q11 deletion syndrome.

GGT2P GGT1

6.68e-041874217097888
Pubmed

Fraction of exhaled nitric oxide values in childhood are associated with 17q11.2-q12 and 17q12-q21 variants.

PAPPA2 LRTM1

7.46e-041974224315451
Pubmed

Activation of the c-H-ras proto-oncogene by retrovirus insertion and chromosomal rearrangement in a Moloney leukemia virus-induced T-cell leukemia.

ZNF143 ZNF850

8.28e-04207422542606
Pubmed

Emergence of the ZNF91 Krüppel-associated box-containing zinc finger gene family in the last common ancestor of anthropoidea.

ZNF143 ZNF850

8.28e-04207427479878
Pubmed

Human transcription factor protein interaction networks.

KMT2C ARID1B ZNF143 ATN1 ATXN2 RBM27 AUTS2 GPATCH8 ZNF850 MNT

8.73e-041429741035140242
Pubmed

High-throughput screen for genes predominantly expressed in the ICM of mouse blastocysts by whole mount in situ hybridization.

KMT2C ZNF143 ZNF322

1.08e-039474316325481
Pubmed

Cloning and enzymatic analysis of 22 novel human ubiquitin-specific proteases.

USP34 USP45

1.10e-032374214715245
Pubmed

The planar cell polarity gene Vangl2 is required for mammalian kidney-branching morphogenesis and glomerular maturation.

CELSR1 GGT2P GGT1

1.11e-039574320843830
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

USP34 KMT2C AUTS2 ADCY9

1.38e-0322574412168954
Pubmed

Positioning of five genes (CASK, ARX, SAT, IMAGE cDNAs 248928 and 253949) from the human X chromosome short arm with respect to evolutionary breakpoints on the mouse X chromosome.

AMELY ZFY

1.40e-032674210920247
InteractionRNF4 interactions

ZNF502 USP34 ZNF16 ARID1B ZNF773 ZNF143 WASHC4 ATN1 ATXN2 RBM27 CAMK2G ZSCAN26 ATL3 AUTS2 ZNF322 GPATCH8 ZNF850 MNT AQR HTT

3.89e-0814127020int:RNF4
Cytoband7q36.1

KMT2C TMEM176B TMEM176A

2.40e-04747437q36.1
Cytoband19q13.43

ZNF773 ZNF497 ZNF582

3.87e-048774319q13.43
CytobandEnsembl 112 genes in cytogenetic band chr19q13

ZNF134 ZNF773 ZNF497 ZNF818P ZNF880 ZNF83 ZNF850 ZNF582

6.68e-041192748chr19q13
Cytoband2q32.1

FSIP2 ZNF804A

1.08e-03307422q32.1
CytobandEnsembl 112 genes in cytogenetic band chr7q36

KMT2C TMEM176B TMEM176A

2.21e-03159743chr7q36
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZNF502 ZNF16 ZNF134 ZNF773 ZNF143 ZNF497 ZFP3 ZNF852 ZSCAN26 ZNF75D ZNF322 ZNF880 ZNF83 ZNF679 ZNF454 ZNF850 ZNF582 ZFY

1.17e-13718481828
GeneFamilyCD molecules|Gamma-glutamyltransferases

GGT2P GGT1

5.28e-0413482564
GeneFamilyCD molecules|Membrane spanning 4-domains

TMEM176B TMEM176A

1.03e-0318482958
GeneFamilyUbiquitin specific peptidases

USP34 USP45

9.70e-0356482366
ToppCelldroplet-Heart-4Chambers-18m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CELSR1 TMEM176B TMEM176A DEGS2 AGRN

1.35e-051837456c4a09c02e30e1f24dde39f8cb8c5b453826ee2e
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(CH25H+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TMEM176B CCDC68 TMEM176A ZNF804A EMILIN1

1.46e-05186745360c3e9e5c3a943e68e6939b4a47821bfc75b553
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PAPPA2 MACC1 MAML2 ZNF83 PHACTR1

1.79e-05194745e577d9e88390b36b5a09b97fe1026089892275a3
ToppCellBL-critical-LOC-Epithelial-unknown_epithelial|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

EPB41L4B CCDC78 KCNN3 RUSC1 CCDC148

1.79e-051947456140ff8e776429c9593607da418b2d9c4f399d41
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TMEM176B CCDC68 TMEM176A ZNF804A EMILIN1

1.93e-05197745236a40eb6c08e1d179cf0fb5450b032975c5f6b6
ToppCell3'-GW_trimst-1-SmallIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TMEM176B CCDC68 TMEM176A ZNF804A EMILIN1

2.02e-05199745a697b3f0760e66bad8ea8d83cf6fea5934692c56
ToppCellTracheal-NucSeq|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations

USP34 KMT2C ARID1B AUTS2 MAML2

2.02e-0519974594b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCelldistal-2-mesenchymal-Alveolar_Fibroblast|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

TMEM176B LRTM1 TMEM176A EMILIN1 MEOX2

2.07e-0520074512b705dabec1b3752a488a891eda1a5123fcdc41
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Krt73|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

TMEM176B TMEM176A CACHD1 MAML2

6.74e-051317449ca209a8652aae603c4a867ea06b06ac51e7d189
ToppCell5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(KCNN3+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KCNN3 ZNF75D AGRN MEOX2

1.36e-04157744beab0ac47202266b04543c02cfcdda012375e879
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-nan|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM176B TMEM176A SLITRK3 GGT1

1.43e-04159744c34a7d227dbda2d7c76f937e1a58552b14bd40b5
ToppCellPCW_05-06-Epithelial-Epithelial_alveolar-distal-epi_SFTPC^high_distal_(9)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

SFTA2 MACC1 CELSR1 EPB41L4B

1.72e-0416774425af48c640e67848594f5902867ba325fc105da4
ToppCellwk_20-22-Mesenchymal-Myofibro_&_SMC-Early_airway_SMC_1|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

ZNF16 USP45 CACHD1 ZNF850

1.76e-0416874453a982869dbf14f6a948589be9f2f3df3b9a7e97
ToppCell3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TMEM176B LRTM1 CCDC68 TMEM176A

1.84e-04170744b5b47fe42617a4c2ebb49c8ed55db3926213a75a
ToppCell356C-Myeloid-Dendritic-cDC_activated|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

TMEM176B ZFP3 TMEM176A LRCH3

1.84e-04170744513d9036aa41d4d902da8baa66a66206abb6f3b0
ToppCellnormal-na-Lymphocytic_B-B_plasma-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

MACC1 CELSR1 KCNN3 ZNF850

1.84e-04170744c5b87974dfddf9780051f7f5693eeeb0c606a3fe
ToppCellNS-critical-d_0-4-Epithelial-FOXN4+|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

TMEM41A QTRT1 ZNF804A CCDC148

1.93e-04172744a00bb44d33658cb3a98accd6b60f3ce964c425b4
ToppCell5'-Adult-LymphNode-Hematopoietic-T_cells-gdT|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RBM27 CCDC78 GPATCH8 LYST

2.01e-04174744ccc79febfcf588d8294ffc712338be96de8a5033
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1-AT2_Progenitor|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SFTA2 MACC1 CELSR1 TMEM176B

2.01e-04174744d0e3d15731de6c19c232e3aa492c39d8151cf4ed
ToppCelldroplet-Thymus-nan-18m-Lymphocytic-Double_negative_thymocyte,_DN3_(Cd8-,_Cd4-),_some_express_pre_TCR_alpha|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM176B EPB41L4B CAMK2G DEGS2

2.01e-041747449eab43885496b8586f8ec5b4bcb1fd5b209218e5
ToppCellfacs-Marrow-T_cells-18m-Hematologic-hematopoietic_stem_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MACC1 TMEM176B CCDC68 TMEM176A

2.06e-041757444be01bf30331162f1998216fb2871a4e626dc440
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_IT_L5/L6_Car3_THEMIS-Exc_L5-6_THEMIS_GPR21|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SPTBN5 ZNF804B CACHD1 ZNF804A

2.10e-04176744ed7ba2a3af3b060dec98b60f09f96000a67f7e63
ToppCellPCW_13-14-Neuronal-Neuronal_postreplicative-neuro_NA|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

TMEM176B ZNF804B TMEM176A ZNF804A

2.15e-041777448c78f7de091f16e86e326a73c9f1429e0232821f
ToppCellPCW_13-14-Neuronal-Neuronal_SCP|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

TMEM176B EPB41L4B TMEM176A ZNF804A

2.15e-04177744621dd82f1393c961d4dd7a615aa52c9df9e36336
ToppCell390C-Lymphocytic-ILC-ILC-1|390C / Donor, Lineage, Cell class and subclass (all cells)

INTS6L ZNF16 ZSCAN26 ZNF75D

2.24e-04179744e7045e27f0eb88f552b31c04b56d78e5ccd7a36c
ToppCellE15.5-Mesenchymal-mesenchymal_fibroblast-alveolar_fibroblast_Wnt2-pa|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

TMEM176B TMEM176A EMILIN1 MEOX2

2.24e-04179744b559f5a72cc9e3e35d05cb539b5c2e006e56e652
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_IT_L5/L6_Car3_THEMIS|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SPTBN5 ZNF804B CACHD1 ZNF804A

2.29e-041807447a9aa96fb8035020640cc7d3df0c41c730516c6f
ToppCellPCW_10-12-Neuronal-Neuronal_postreplicative|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

TMEM176B ZNF804B TMEM176A ZNF804A

2.34e-041817441aebb62ed4439db444ee9d30688212b86ee3d9ef
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_IT_L5/L6_Car3_THEMIS|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SPTBN5 ZNF804B CACHD1 ZNF804A

2.34e-0418174413270b6ba6a9c8e5681c6f40000c643ce1d9344a
ToppCellPCW_10-12-Neuronal-Neuronal_postreplicative-neuro_NA|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

TMEM176B ZNF804B TMEM176A ZNF804A

2.34e-041817446aee2ddee4790250ef3b2ef0038bd9839925c995
ToppCellPCW_10-12-Neuronal|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

TMEM176B ZNF804B TMEM176A ZNF804A

2.34e-04181744381b553e2cae65ce6be100662a5f9f963353840c
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_IT_L5/L6_Car3_THEMIS-Exc_L5-6_THEMIS_IL7R|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SPTBN5 ZNF804B CACHD1 ZNF804A

2.34e-041817443e3c903b522dced6bec5dc447cc3f8bf9a9749e3
ToppCellMesenchymal_cells-Adipo-CAR|Mesenchymal_cells / Lineage and Cell class

TMEM176B EPB41L4B TMEM176A PHACTR1

2.34e-041817441cfb03eb03a37b036b4eeacec69c9b8163af1ee4
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.6.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TMEM176B TMEM176A ZNF804A PHACTR1

2.39e-041827444234d0cc57b5266a5e03133c75c7918abe48465e
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_IT_L5/L6_Car3_THEMIS-Exc_L5-6_THEMIS_GPR21|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SPTBN5 ZNF804B CACHD1 ZNF804A

2.39e-041827441647367b75b4b107af06bb934394168230cfd7c2
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PAPPA2 LRTM1 LYST CCDC148

2.39e-04182744a8cc56f32efe180e8fb5d69dbe606a794b3db700
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Endothelial-endocardial_endothelial_cells|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CELSR1 TMEM176B CACHD1 DEGS2

2.44e-04183744b0b5a41f1a40f9c946d0dc8b67eaccdd9f9b73a5
ToppCellCOVID-19-Epithelial_cells-AT2|COVID-19 / group, cell type (main and fine annotations)

SFTA2 AUTS2 CACHD1 PHACTR1

2.49e-04184744369b82f793deab672204558ae4e112cfa5aa9ccc
ToppCell343B-Epithelial_cells-Epithelial-I_(AT1)|343B / Donor, Lineage, Cell class and subclass (all cells)

SFTA2 LRTM1 AGRN GGT1

2.49e-04184744cb15d6bae52c5ec251c2235859dc7e65f630ae23
ToppCellPCW_13-14-Neuronal|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

TMEM176B ZNF804B TMEM176A ZNF804A

2.49e-0418474465cf3460125e3dbc34978957bc138a449f71f7df
ToppCell343B-Epithelial_cells-Epithelial-I_(AT1)-|343B / Donor, Lineage, Cell class and subclass (all cells)

SFTA2 LRTM1 AGRN GGT1

2.49e-04184744bde4eaabd3e9bdaed23867d23a919b9d84b52d4b
ToppCellControl-Endothelial-Endothelial-Vein|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CCDC68 LYST PHACTR1 MEOX2

2.60e-0418674492092f11ecce22c14f244e42c499af0822977e6f
ToppCellPCW_13-14-Neuronal-Neuronal_postreplicative|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

TMEM176B ZNF804B TMEM176A ZNF804A

2.60e-04186744cf96f880e6e22189593ce1357c55e65c34644559
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CELSR1 CAMK2G ZNF804B ADCY9

2.60e-041867445784d255e9ca449d375d81938d0fbbd8a7eb44f6
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SFTA2 MACC1 CELSR1 AUTS2

2.60e-04186744e83718fabb057100835d3357df407f283d23fe16
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PAPPA2 MACC1 ZNF83 CCDC148

2.65e-0418774487b3d0478693d4c54ff06b74e5903036b9c1ee6a
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PAPPA2 MACC1 ZNF83 CCDC148

2.65e-0418774442a1267bfc27b4460b8409ada580a87c4385841c
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PAPPA2 MACC1 ZNF83 CCDC148

2.65e-0418774464afdea159f5e67a1e5cea35ce898aae6e80aea5
ToppCellfacs-Heart-LA-24m-Endothelial-endothelial_cell_of_endocardium|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CELSR1 TMEM176B TMEM176A DEGS2

2.65e-04187744d9943e65eedab73d141eae524e2411653a751705
ToppCellfacs-Heart-LA-24m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CELSR1 TMEM176B TMEM176A DEGS2

2.65e-041877447b13c3b67d66f3afb410141d5471c9e78a4d8623
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PAPPA2 ZNF83 LYST CCDC148

2.65e-0418774477886f99c229610abd28c4c370d2c7d1536c9782
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

MACC1 CELSR1 AGRN PHACTR1

2.70e-04188744eea652bab161f19148a883e7e3fe2523b36b3cea
ToppCell343B-Lymphocytic-ILC-ILC-1|343B / Donor, Lineage, Cell class and subclass (all cells)

INTS6L USF3 ZNF322 HTT

2.70e-041887448f6b45ad82bde65e044d17f0edbc3db90d457915
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KCNN3 CACHD1 MAML2 CCDC148

2.70e-04188744bc089cd73d283ed7d2ecbb3936673b4edc89f666
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KCNN3 CACHD1 MAML2 CCDC148

2.70e-04188744eec3d353e51358db4c7621265ee0fdd4298e5b0e
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SFTA2 MACC1 CELSR1 AUTS2

2.70e-041887444bdf8d49af0e9da349b16e3f012e1b0eec04cc4f
ToppCellPCW_13-14-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

MACC1 CELSR1 EPB41L4B PHACTR1

2.70e-041887440d86044bc340e3efb90d0022dd299873639d831c
ToppCellkidney_cells-Hypertensive_with+without-CKD|kidney_cells / Celltypes from Cells and Nuclei per compartment and clinical group

PAPPA2 MACC1 ARID1B TMEM176B

2.70e-0418874490188b60ff893754f7938fe8edab79758827168e
ToppCell343B-Lymphocytic-ILC|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

INTS6L ZNF773 USF3 ZNF322

2.76e-04189744c26428871dc3261327d89cacaba6e21e004ff1f3
ToppCellnormal_Lung-Fibroblasts-Undetermined|normal_Lung / Location, Cell class and cell subclass

TMEM176B TMEM176A EMILIN1 MEOX2

2.81e-0419074430d4658bcc6796f0cdf54cc029f4bb904b13ef66
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PAPPA2 MACC1 CCDC148 PHACTR1

2.81e-041907443fc9e18c7441c0ae8cda65753cc42d0520f4e116
ToppCelldroplet-Heart-4Chambers-18m-Endothelial-endocardial_endothelial_cells|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CELSR1 TMEM176B TMEM176A DEGS2

2.81e-041907446f71a9f74af7cd9a674753cfc9833ebe5bba0fa2
ToppCelldroplet-Lung-3m-Mesenchymal-fibroblast-alveolar_fibroblast|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TMEM176B TMEM176A EMILIN1 MEOX2

2.87e-04191744509230f50568e5a8ecf08edc4d58f9e2aa96efe9
ToppCelldroplet-Lung-3m-Mesenchymal-fibroblast|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TMEM176B TMEM176A EMILIN1 MEOX2

2.87e-0419174444a9a6768084dafc641ad455b65862bfd4cc0cb9
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PAPPA2 MACC1 CCDC148 PHACTR1

2.87e-041917445a67ff17fb4b9eff641176dff07830c9cd73754e
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PAPPA2 MACC1 CCDC148 PHACTR1

2.87e-0419174455ab2854a02cdcfc395e49870ccb7290b5e5471d
ToppCellChildren_(3_yrs)-Epithelial|Children_(3_yrs) / Lineage, Cell type, age group and donor

CELSR1 AUTS2 CACHD1 PHACTR1

2.87e-04191744e432c6e1ae82dddf84314ce73d2b7a991630d905
ToppCelldroplet-Lung-3m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l49|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TMEM176B TMEM176A EMILIN1 MEOX2

2.87e-041917440b3dbbc35d9970d3c749aef16dda59886b960e3d
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Epithelial-Epithelial,_Airway-ciliated_cell-Epi-Ciliated|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

SFTA2 MACC1 ZNF852 DEGS2

2.93e-04192744a22952b885c8a7704a4a9602fa03e4f2c786bf75
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TMEM176B TMEM176A DEGS2 AGRN

2.93e-04192744967122c53af25b8f19a8411b4553d764c8d51c4d
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Epithelial-Epithelial,_Airway-ciliated_cell|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

SFTA2 MACC1 ZNF852 DEGS2

2.93e-04192744dcf2d0c2e8868104c4dba410456207f0d947029a
ToppCell(1)_Control_(PBS)-(3)_LEPR+_perivascular_cells|(1)_Control_(PBS) / Stress and Cell class

TMEM176B EPB41L4B TMEM176A PHACTR1

2.93e-0419274440f380f5f0bed63a7404be050838ebd01ef08987
ToppCellAdult-Epithelial|Adult / Lineage, Cell type, age group and donor

CELSR1 AUTS2 CACHD1 PHACTR1

2.93e-04192744efb962a5fd3b9bdfd8cf8d13c435e29c8271713e
ToppCelldroplet-Lung-3m-Mesenchymal|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TMEM176B TMEM176A EMILIN1 MEOX2

2.93e-04192744086b47f87283cd41139cd56686011f8b5821b0da
ToppCell343B-Lymphocytic-ILC-ILC-1|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

INTS6L USF3 ZNF322 HTT

2.93e-04192744445985fe1bcd33e4f0a1704b27988fbfc9334538
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts-Peribronchial_fibroblasts_L.2.1.3.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TMEM176B TMEM176A EMILIN1 MEOX2

2.99e-04193744b05361ffe111a38cfa26eb86e4ae62c15ac99b7b
ToppCellE15.5-Mesenchymal|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

TMEM176B TMEM176A EMILIN1 MEOX2

2.99e-0419374422a9f5b61f197757f72840b9cb849cdb20430e72
ToppCellnucseq|World / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

USP34 KMT2C ARID1B MAML2

2.99e-04193744779276e775cb2492e8dd36436295a536084a6415
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PAPPA2 MACC1 ZNF83 PHACTR1

2.99e-04193744f42a0f02ed00fe1bb833ff0a0640d9131bca89bd
ToppCellE15.5-Mesenchymal-mesenchymal_fibroblast|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

TMEM176B TMEM176A EMILIN1 MEOX2

2.99e-04193744b637e1c47a98009e7d19a6daac78f888fd12748f
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PAPPA2 MACC1 ZNF83 PHACTR1

2.99e-0419374442df7ed37d11fb542b4d1d714b6f87ae8e1396a6
ToppCellwk_20-22-Epithelial-Proximal_epithelial-MUC16+_ciliated|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

CELSR1 EPB41L4B CCDC78 DEGS2

3.05e-04194744756082a0f5953b52229bb60d40b84701cb6cb23d
ToppCell10x_3'_v2v3-Non-neoplastic-Lymphoid-CD4/CD8-CD8_NK_sig-C|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ZFP3 RBM27 AUTS2 ZFY

3.05e-041947446be74e4ba631b0c46cef2c580553f4c1ed29579e
ToppCellE17.5-Mesenchymal-mesenchymal_fibroblast|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

TMEM176B TMEM176A EMILIN1 MEOX2

3.05e-04194744f15e81ff12525523c62d13105cf264ea72205e2e
ToppCellE15.5-Mesenchymal-mesenchymal_fibroblast-mesenchymal_progenitor_cell|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

TMEM176B TMEM176A EMILIN1 MEOX2

3.05e-04194744f2f7b9aad7588c8020a4850ff9333e1db8eafac7
ToppCellIPF-Endothelial-VE_Venous|Endothelial / Disease state, Lineage and Cell class

TMEM176B CCDC68 TMEM176A LYST

3.05e-04194744e8a9005963704286bcc50785bda8d7d63ec001b1
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PAPPA2 MACC1 ZNF83 PHACTR1

3.11e-04195744938b31dbf1674ee6fd0123bc88391ddcaf151217
ToppCell15-Airway-Epithelial|Airway / Age, Tissue, Lineage and Cell class

SFTA2 CELSR1 TMEM176A DEGS2

3.11e-04195744cd0af7e260e4f0c5a9ecdfa93619f37b2a9308a5
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PAPPA2 MACC1 ZNF83 PHACTR1

3.11e-04195744d39e9e6544f49e677ebe528c6fe60b99a3630e30
ToppCell3'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TMEM176B CCDC68 TMEM176A EMILIN1

3.11e-04195744bad7f2162000f29488b3c4b903dcac9a818621f7
ToppCellBronchial-NucSeq|Bronchial / Cell types per location group and 10X technology with lineage, and cell group designations

ARID1B AUTS2 MAML2 ADCY9

3.17e-04196744ab53c742866945545a92e2e61850d63c80d9a2a6
ToppCell367C-Fibroblasts-Fibroblast-C_(Myofibroblast)-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

TMEM176B TMEM176A EMILIN1 MEOX2

3.17e-041967446730743cf088c419ccc2d28765769fc09d3ba6a7
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-Stromal_2_(CH25H+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TMEM176B CCDC68 TMEM176A EMILIN1

3.17e-041967441f47916c2663bd88c1e7c19c6a7688f4c7173ad2
ToppCellE17.5-Mesenchymal-mesenchymal_fibroblast-mesenchymal_progenitor_cell|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

TMEM176B TMEM176A EMILIN1 MEOX2

3.17e-04196744028a06ed92f1c058dcbeacd335625bf529e87a7b
ToppCell367C-Fibroblasts-Fibroblast-C_(Myofibroblast)|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

TMEM176B TMEM176A EMILIN1 MEOX2

3.17e-0419674421dab89f3699037138a9c7a0e4dc98739a9fad9c
ToppCell11.5-Distal-Epithelial-Bud_tip_adjacent|Distal / Age, Tissue, Lineage and Cell class

SFTA2 MACC1 CELSR1 DEGS2

3.17e-04196744a6a242868df0d2ff30825624a8d7c0367527594d
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TMEM176B CCDC68 TMEM176A EMILIN1

3.23e-04197744ea746772adb9df4ddb0508d4ef35f2027bf09c35
ToppCelldistal-Endothelial-Vein-1|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

TMEM176B TMEM176A CACHD1 LYST

3.23e-041977443d71c93da4b88ebbd58e68ed3dbf610d4bcfc4f5
ToppCell3'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TMEM176B CCDC68 TMEM176A EMILIN1

3.23e-04197744eb07545bef5ad506fbbe3a1f99131f26c1447a31
ToppCell3'-GW_trimst-1-SmallIntestine-Mesenchymal-fibroblastic-Stromal_2_(CH25H+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TMEM176B CCDC68 TMEM176A ZNF804A

3.23e-04197744467e7cbf511d3bcc701923603032aaf0bba2736d
Diseaseaflatoxins-related hepatocellular carcinoma (biomarker_via_orthology)

GGT2P GGT1

1.12e-047692DOID:5022 (biomarker_via_orthology)
Diseasealcohol dependence (biomarker_via_orthology)

GGT2P GGT1

1.50e-048692DOID:0050741 (biomarker_via_orthology)
Diseasesevere acute respiratory syndrome, COVID-19

LRTM1 AUTS2 MAML2 ZNF83 LYST CCDC148

6.26e-04447696EFO_0000694, MONDO_0100096
Diseasecervical artery dissection

ZNF804A PHACTR1

7.16e-0417692EFO_1000059
Diseasebirth weight, parental genotype effect measurement

PAPPA2 USF3 ATXN2 KCNN3

1.08e-03192694EFO_0004344, EFO_0005939
Diseasegrip strength measurement

CELSR1 AUTS2 ZNF322 ADCY9 PHACTR1

1.38e-03350695EFO_0006941
Diseaseattention deficit hyperactivity disorder, unipolar depression, bipolar disorder, autism spectrum disorder, schizophrenia

SFTA2 CCDC68 ZNF804A

1.73e-03101693EFO_0003756, EFO_0003761, EFO_0003888, MONDO_0004985, MONDO_0005090
Diseaselongevity, healthspan, parental longevity

ATXN2 HTT

2.10e-0329692EFO_0004300, EFO_0007796, EFO_0009762
Diseasecoronary artery disease, factor VII measurement

ATXN2 ZSCAN26 PHACTR1

2.27e-03111693EFO_0001645, EFO_0004619
Diseasefactor XI measurement, coronary artery disease

ATXN2 ZSCAN26 PHACTR1

2.51e-03115693EFO_0001645, EFO_0004694
Diseasevon Willebrand factor measurement, coronary artery disease

ATXN2 ZSCAN26 PHACTR1

2.70e-03118693EFO_0001645, EFO_0004629
Diseasecardiovascular disease

SPTBN5 USP34 ATXN2 ADCY9 CCDC148

4.35e-03457695EFO_0000319

Protein segments in the cluster

PeptideGeneStartEntry
QQHPLTHTLQSHHHI

AMELY

86

Q99218
QHHTLQHSHPHIEFN

CCDC148

141

Q8NFR7
VSTHHHHHQQQQQQQ

ATN1

476

P54259
HVHACTHQISLHVAS

AGRN

581

O00468
HHSHHLQAAVTVHTV

CACHD1

1256

Q5VU97
HHLHHHHALQQQLNQ

ARID1B

181

Q8NFD5
HLIQTTHHYHQTLLQ

AQR

1371

O60306
HTAHVLINVTDANTH

CELSR1

771

Q9NYQ6
EQISHLQFVIHSQHQ

CCDC68

241

Q9H2F9
QQQTLSHLSQQHHHL

RBM27

691

Q9P2N5
HHLHNNISHINSRSS

INTS6L

846

Q5JSJ4
HNLRILNVSHNHISH

LRRD1

211

A4D1F6
ASHNQLSHTDLELHQ

LRCH3

456

Q96II8
QTRTLHLQDNQIHHL

LRTM1

51

Q9HBL6
LQHQQHTTVISGHTS

KMT2C

3311

Q8NEZ4
VQHHQHQAAQALHLA

ATXN2

1171

Q99700
SVHQISLHNSDTEHI

FSIP2

1196

Q5CZC0
SITTVQHAILQHHAA

GPATCH8

1371

Q9UKJ3
DNHAHQTLLHHPNAT

KCNN3

226

Q9UGI6
QTLLHHPNATHNHQH

KCNN3

231

Q9UGI6
RTEFHQHQHQHQHTH

AUTS2

521

Q8WXX7
AVSHIAHTLSHQQVN

MNT

516

Q99583
HHHHHQQQQHQALQT

MEOX2

76

P50222
VAQHHHTVLPSQIQH

PHACTR1

271

Q9C0D0
HHHHQQHLLNSSNNG

MAML2

131

Q8IZL2
NVTHHQNVLFHHTTS

PAPPA2

1326

Q9BXP8
TLHHTQHQDHNVVTG

HTT

361

P42858
NHSLTLAIHDISHNA

DEGS2

81

Q6QHC5
HQQLLHHHSTEVSCD

ADCY9

6

O60503
VDIQITTHHLHEQHE

CCDC78

66

A2IDD5
HQHEEIQNVRNHIHS

ATL3

241

Q6DD88
AHHCQHLSVTSAQSH

LYST

746

Q99698
AHAHQSIHNSDQILL

MACC1

151

Q6ZN28
VSTHDQELGHLNNHH

EMILIN1

251

Q9Y6C2
QHQHQHHSNYSLSLT

EPB41L4B

511

Q9H329
CIHQILESVNHIHQH

CAMK2G

116

Q13555
HHHTQIASTFIAVVQ

GGT2P

531

P36268
NLNHIHLQHVSLGLH

RUSC1

11

Q9BVN2
HLQLNETSTANHIHS

TMEM41A

246

Q96HV5
SDNTAALHHLTVHNI

QTRT1

336

Q9BXR0
HTHIDVHIHQESALA

TMEM176A

16

Q96HP8
QLNTIVTVNHHHPHH

SLITRK3

826

O94933
QHQDSHHITIHTHRT

REELD1

46

A0A1B0GV85
THVNVHIHQESALTQ

TMEM176B

21

Q3YBM2
QVSAHGAHVSHLAQQ

SPTBN5

581

Q9NRC6
QHQVAAHHEATVRSH

XIRP2

2906

A4UGR9
VFTQNSHLANHHRIH

ZNF880

276

Q6PDB4
FRAHSQLIHHQETHS

ZNF497

171

Q6ZNH5
GHQQHSHHLVTTETR

ZNF143

581

P52747
HQHTSITTIHHTFLQ

ZNF804B

1201

A4D1E1
LTCQHVSHAISVNHV

USP45

36

Q70EL2
EHHSPQSHQQSLLGH

SPEM2

341

Q0P670
VSQLHQHQIIHTREN

ZNF679

196

Q8IYX0
HQSSALLQHQTVHIG

ZNF322

361

Q6U7Q0
HQHHSLHTCLNDQNS

USF3

266

Q68DE3
AFSHCSQLIHHQVIH

ZNF582

431

Q96NG8
HNSTLVQHHRIHTGV

ZNF773

286

Q6PK81
SQALLLTHHQRIHSH

ZSCAN26

376

Q16670
SHNTNLHTHQRIHTG

ZNF75D

431

P51815
HSSHLIQHQRLHNGE

ZNF852

226

Q6ZMS4
FNQNTHLIHHQRIHT

ZNF502

276

Q8TBZ5
VVADSVSHITQHLQH

WASHC4

496

Q2M389
VSHITQHLQHQALHS

WASHC4

501

Q2M389
SQNSHLVNHQRIHTG

ZNF818P

71

Q6ZRF7
SQSSHLIQHQIIHTG

ZNF16

611

P17020
HQSTHLIHHQRIHTG

ZNF454

226

Q8N9F8
TSVTLHHARSQHHVV

SFTA2

61

Q6UW10
INSHAELTSHLQQHL

USP34

806

Q70CQ2
QSVSQHNHHVILSEA

TRAV8-1

21

A0A0A6YYK1
FTSHSTLIQHQQIHT

ZNF850

766

A8MQ14
HHSNLIVHQRVHNGA

ZNF134

271

P52741
HHISHLAQHQRIHTG

ZNF83

271

P51522
AFSQNSHLVQHHRIH

ZNF83

381

P51522
VQQHTLVHQESKTHQ

ZFY

616

P08048
FIQSSHLIHHHRIHT

ZFP3

206

Q96NJ6
TTIHHTVLQQHAAAA

ZNF804A

1096

Q7Z570
HHHTQIASTFIAVVQ

GGT1

531

P19440