Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	nicotinic acid receptor activity	HCAR3 HCAR2	1.63e-05	2	81	2	GO:0070553
HumanPheno	Adenocarcinoma of the colon	POLD1 RPL35 HEATR3 RPL18	4.51e-05	35	30	4	HP:0040276
HumanPheno	Gastrointestinal carcinoma	POLD1 RPL35 HEATR3 AXIN2 RPL18	6.47e-05	75	30	5	HP:0002672
HumanPheno	Malignant gastrointestinal tract tumors	POLD1 RPL35 HEATR3 AXIN2 RPL18	6.47e-05	75	30	5	HP:0006749
HumanPheno	Adenocarcinoma of the large intestine	POLD1 RPL35 HEATR3 RPL18	6.97e-05	39	30	4	HP:0040275
HumanPheno	Neoplasm of the colon	POLD1 RPL35 HEATR3 AXIN2 RPL18	9.37e-05	81	30	5	HP:0100273
HumanPheno	Adenocarcinoma of the intestines	POLD1 RPL35 HEATR3 RPL18	1.03e-04	43	30	4	HP:0040273
HumanPheno	Sarcoma	POLD1 ESR1 PIEZO1 RPL35 HEATR3 AXIN2 RPL18	1.66e-04	210	30	7	HP:0100242
HumanPheno	Eruptive vellus hair cyst	KRT6A KRT6B	2.00e-04	4	30	2	HP:0025248
HumanPheno	Steatocystoma multiplex	KRT6A KRT6B	2.00e-04	4	30	2	HP:0012035
HumanPheno	Steroid-responsive anemia	RPL35 RPL18	2.00e-04	4	30	2	HP:0033074
HumanPheno	Abnormal hemoglobin	PIEZO1 RPL35 CFI HEATR3 RPL18	2.21e-04	97	30	5	HP:0011902
HumanPheno	Increased mean corpuscular volume	PIEZO1 RPL35 HEATR3 RPL18	2.34e-04	53	30	4	HP:0005518
HumanPheno	Linear arrays of macular hyperkeratoses in flexural areas	KRT6A KRT6B	3.32e-04	5	30	2	HP:0007490
HumanPheno	Hyperplastic callus formation	KRT6A KRT6B	3.32e-04	5	30	2	HP:0030268
HumanPheno	Abnormal radial artery morphology	RPL35 HEATR3 RPL18	4.37e-04	26	30	3	HP:0031640
HumanPheno	Elevated red cell adenosine deaminase activity	RPL35 HEATR3 RPL18	4.37e-04	26	30	3	HP:0030270
HumanPheno	Radial artery aplasia	RPL35 HEATR3 RPL18	4.37e-04	26	30	3	HP:0020118
HumanPheno	Abnormal mean corpuscular volume	PIEZO1 RPL35 HEATR3 RPL18	4.58e-04	63	30	4	HP:0025065
HumanPheno	Neoplasm of the large intestine	POLD1 RPL35 HEATR3 AXIN2 RPL18	4.68e-04	114	30	5	HP:0100834
HumanPheno	Abnormal erythrocyte adenosine deaminase activity	RPL35 HEATR3 RPL18	4.90e-04	27	30	3	HP:4000209
HumanPheno	Nonimmune hydrops fetalis	PIEZO1 RPL35 HEATR3 RPL18	5.16e-04	65	30	4	HP:0001790
HumanPheno	Macrocytic dyserythropoietic anemia	RPL35 HEATR3 RPL18	5.47e-04	28	30	3	HP:0005532
HumanPheno	White lesion of the oral mucosa	KRT6A KRT6B KRT6C	5.47e-04	28	30	3	HP:0025125
HumanPheno	Oral leukoplakia	KRT6A KRT6B KRT6C	5.47e-04	28	30	3	HP:0002745
HumanPheno	Abnormality of the scalp hair	KIFBP SETD5 RPL35 KAT6B USP48 HEATR3 AXIN2 CHST3 RPL18	6.04e-04	433	30	9	HP:0100037
HumanPheno	Drusen	CTNNA1 PRPF8 CFI	6.08e-04	29	30	3	HP:0011510
HumanPheno	Pure red cell aplasia	RPL35 HEATR3 RPL18	6.72e-04	30	30	3	HP:0012410
HumanPheno	Webbed neck	PIEZO1 RPL35 HEATR3 CHST3 RPL18	6.89e-04	124	30	5	HP:0000465
HumanPheno	Onychogryposis of toenails	KRT6A KRT6B	6.91e-04	7	30	2	HP:0008401
HumanPheno	Onychogryposis	KRT6A KRT6B	6.91e-04	7	30	2	HP:0001819
HumanPheno	Erythroid hypoplasia	RPL35 HEATR3 RPL18	7.41e-04	31	30	3	HP:0012133
MousePheno	abnormal eye muscle morphology	KIFBP ZMYND11 SETD5 RUNDC1	4.67e-05	46	61	4	MP:0003686
MousePheno	dilated liver sinusoidal space	KIFBP ZMYND11 SETD5 RUNDC1	5.53e-05	48	61	4	MP:0000602
Domain	HCAR2/3_rcpt	HCAR3 HCAR2	1.77e-05	2	79	2	IPR028017
Domain	Keratin_2_head	KRT6A KRT6B KRT6C	1.38e-04	24	79	3	IPR032444
Domain	Keratin_2_head	KRT6A KRT6B KRT6C	1.38e-04	24	79	3	PF16208
Domain	Keratin_II	KRT6A KRT6B KRT6C	1.77e-04	26	79	3	IPR003054
Domain	WWE	DDHD2 TIPARP	1.13e-03	12	79	2	PS50918
Domain	WWE	DDHD2 TIPARP	1.13e-03	12	79	2	PF02825
Domain	WWE-dom	DDHD2 TIPARP	1.13e-03	12	79	2	IPR004170
Domain	RECEPTOR_TYR_KIN_V_2	EPHB2 EPHA6	1.56e-03	14	79	2	PS00791
Domain	RECEPTOR_TYR_KIN_V_1	EPHB2 EPHA6	1.56e-03	14	79	2	PS00790
Domain	Eph_TM	EPHB2 EPHA6	1.56e-03	14	79	2	IPR027936
Domain	Tyr_kinase_rcpt_V_CS	EPHB2 EPHA6	1.56e-03	14	79	2	IPR001426
Domain	EPH_lbd	EPHB2 EPHA6	1.56e-03	14	79	2	SM00615
Domain	Ephrin_lbd	EPHB2 EPHA6	1.56e-03	14	79	2	PF01404
Domain	EphA2_TM	EPHB2 EPHA6	1.56e-03	14	79	2	PF14575
Domain	Tyr_kinase_ephrin_rcpt	EPHB2 EPHA6	1.56e-03	14	79	2	IPR016257
Domain	Ephrin_rcpt_lig-bd_dom	EPHB2 EPHA6	1.56e-03	14	79	2	IPR001090
Domain	EPH_LBD	EPHB2 EPHA6	1.56e-03	14	79	2	PS51550
Domain	Intermediate_filament_CS	KRT6A KRT6B KRT6C	2.41e-03	63	79	3	IPR018039
Domain	SAM_1	EPHB2 EPHA6 DDHD2	3.00e-03	68	79	3	PF00536
Domain	PDZ	LMO7 MAST1 ARHGAP21 PDZRN3	3.02e-03	141	79	4	PF00595
Domain	Filament	KRT6A KRT6B KRT6C	3.39e-03	71	79	3	SM01391
Domain	zf-MYND	SMYD4 ZMYND11	3.52e-03	21	79	2	PF01753
Domain	IF	KRT6A KRT6B KRT6C	3.52e-03	72	79	3	PS00226
Domain	PDZ	LMO7 MAST1 ARHGAP21 PDZRN3	3.59e-03	148	79	4	SM00228
Domain	Filament	KRT6A KRT6B KRT6C	3.66e-03	73	79	3	PF00038
Domain	-	LMO7 MAST1 ARHGAP21 PDZRN3	3.77e-03	150	79	4	2.30.42.10
Domain	PDZ	LMO7 MAST1 ARHGAP21 PDZRN3	3.86e-03	151	79	4	PS50106
Domain	Znf_MYND	SMYD4 ZMYND11	3.86e-03	22	79	2	IPR002893
Domain	ZF_MYND_1	SMYD4 ZMYND11	3.86e-03	22	79	2	PS01360
Domain	ZF_MYND_2	SMYD4 ZMYND11	3.86e-03	22	79	2	PS50865
Domain	PDZ	LMO7 MAST1 ARHGAP21 PDZRN3	3.95e-03	152	79	4	IPR001478
Domain	IF	KRT6A KRT6B KRT6C	4.10e-03	76	79	3	IPR001664
Pubmed	Genetic variants in pachyonychia congenita-associated keratins increase susceptibility to tooth decay.	KRT6A KRT6B KRT6C	1.26e-08	3	82	3	29357356
Pubmed	Cloning and characterization of multiple human genes and cDNAs encoding highly related type II keratin 6 isoforms.	KRT6A KRT6B KRT6C	1.26e-08	3	82	3	7543104
Pubmed	Pachyonychia Congenita	KRT6A KRT6B KRT6C	1.26e-07	5	82	3	20301457
Pubmed	CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality.	DDX47 KRT6A KRT6B PAXBP1 KRT6C NAT10 MCM5 RPL35 PRPF8 RPL18 KPNA3	1.85e-07	605	82	11	28977666
Pubmed	Keratin 6 is not essential for mammary gland development.	KRT6A KRT6B ESR1	2.51e-07	6	82	3	16790075
Pubmed	Prediction of local recurrence, distant metastases, and death after breast-conserving therapy in early-stage invasive breast cancer using a five-biomarker panel.	KRT6A KRT6B ESR1	4.39e-07	7	82	3	19720911
Pubmed	The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation.	CDC37 KRT6A KRT6B KRT6C AMOT NAT10 MCM5 RPL35 PRPF8 HEATR3 LSM3 RPL18 KPNA3	2.92e-06	1153	82	13	29845934
Pubmed	Global mapping of herpesvirus-host protein complexes reveals a transcription strategy for late genes.	CDC37 TAOK3 LMO7 SEC62 EPB41L5 CTNNA1 HEATR3 LSM3 KPNA3	4.74e-06	533	82	9	25544563
Pubmed	Activated niacin receptor HCA2 inhibits chemoattractant-mediated macrophage migration via Gβγ/PKC/ERK1/2 pathway and heterologous receptor desensitization.	HCAR3 HCAR2	5.49e-06	2	82	2	28186140
Pubmed	A reporter transgene based on a human keratin 6 gene promoter is specifically expressed in the periderm of mouse embryos.	KRT6A KRT6B	5.49e-06	2	82	2	11118885
Pubmed	The Immunometabolomic Interface Receptor Hydroxycarboxylic Acid Receptor 2 Mediates the Therapeutic Effects of Dimethyl Fumarate in Autoantibody-Induced Skin Inflammation.	HCAR3 HCAR2	5.49e-06	2	82	2	30154797
Pubmed	The niacin/butyrate receptor GPR109A suppresses mammary tumorigenesis by inhibiting cell survival.	HCAR3 HCAR2	5.49e-06	2	82	2	24371223
Pubmed	High dietary niacin may increase prostaglandin formation but does not increase tumor formation in ApcMin/+ mice.	HCAR3 HCAR2	5.49e-06	2	82	2	21774590
Pubmed	The role of HCA2 (GPR109A) in regulating macrophage function.	HCAR3 HCAR2	5.49e-06	2	82	2	23882124
Pubmed	Crosstalk between microbiome, regulatory T cells and HCA2 orchestrates the inflammatory response in a murine psoriasis model.	HCAR3 HCAR2	5.49e-06	2	82	2	36891315
Pubmed	GPR109a Regulates Phenotypic and Functional Alterations in Macrophages and the Progression of Type 1 Diabetes.	HCAR3 HCAR2	5.49e-06	2	82	2	36208084
Pubmed	Expression of MK6a dominant-negative and C-terminal mutant transgenes in mice has distinct phenotypic consequences in the epidermis and hair follicle.	KRT6A KRT6B	5.49e-06	2	82	2	10550543
Pubmed	The mouse keratin 6 isoforms are differentially expressed in the hair follicle, footpad, tongue and activated epidermis.	KRT6A KRT6B	5.49e-06	2	82	2	10550545
Pubmed	Parabacteroides distasonis ameliorates insulin resistance via activation of intestinal GPR109a.	HCAR3 HCAR2	5.49e-06	2	82	2	38007572
Pubmed	The role of the C-terminus of the human hydroxycarboxylic acid receptors 2 and 3 in G protein activation using Gα-engineered yeast cells.	HCAR3 HCAR2	5.49e-06	2	82	2	26656756
Pubmed	Biased allosteric activation of ketone body receptor HCAR2 suppresses inflammation.	HCAR3 HCAR2	5.49e-06	2	82	2	37597514
Pubmed	The Role of GPR109a Signaling in Niacin Induced Effects on Fed and Fasted Hepatic Metabolism.	HCAR3 HCAR2	5.49e-06	2	82	2	33924461
Pubmed	Hydroxycarboxylic acid receptor 2 mediates dimethyl fumarate's protective effect in EAE.	HCAR3 HCAR2	5.49e-06	2	82	2	24691444
Pubmed	Ketone Body 3-Hydroxybutyrate Ameliorates Atherosclerosis via Receptor Gpr109a-Mediated Calcium Influx.	HCAR3 HCAR2	5.49e-06	2	82	2	33977048
Pubmed	Butyrate ameliorates caerulein-induced acute pancreatitis and associated intestinal injury by tissue-specific mechanisms.	HCAR3 HCAR2	5.49e-06	2	82	2	31347703
Pubmed	PUMA-G, an IFN-gamma-inducible gene in macrophages is a novel member of the seven transmembrane spanning receptor superfamily.	HCAR3 HCAR2	5.49e-06	2	82	2	11745392
Pubmed	Loss of GPR109A/HCAR2 induces aging-associated hepatic steatosis.	HCAR3 HCAR2	5.49e-06	2	82	2	30659164
Pubmed	Niacin-induced hyperglycemia is partially mediated via niacin receptor GPR109a in pancreatic islets.	HCAR3 HCAR2	5.49e-06	2	82	2	25622782
Pubmed	GPR109A mediates the effects of hippuric acid on regulating osteoclastogenesis and bone resorption in mice.	HCAR3 HCAR2	5.49e-06	2	82	2	33420329
Pubmed	Expression and localization of GPR109A (PUMA-G/HM74A) mRNA and protein in mammalian retinal pigment epithelium.	HCAR3 HCAR2	5.49e-06	2	82	2	19223991
Pubmed	Molecular identification of nicotinic acid receptor.	HCAR3 HCAR2	5.49e-06	2	82	2	12646212
Pubmed	PUMA-G and HM74 are receptors for nicotinic acid and mediate its anti-lipolytic effect.	HCAR3 HCAR2	5.49e-06	2	82	2	12563315
Pubmed	Niacin increases adiponectin and decreases adipose tissue inflammation in high fat diet-fed mice.	HCAR3 HCAR2	5.49e-06	2	82	2	23967184
Pubmed	The two functional keratin 6 genes of mouse are differentially regulated and evolved independently from their human orthologs.	KRT6A KRT6B	5.49e-06	2	82	2	9790766
Pubmed	Involvement of the Niacin Receptor GPR109a in the LocalControl of Glucose Uptake in Small Intestine of Type 2Diabetic Mice.	HCAR3 HCAR2	5.49e-06	2	82	2	26371038
Pubmed	Alloreactive T cells deficient of the short-chain fatty acid receptor GPR109A induce less graft-versus-host disease.	HCAR3 HCAR2	5.49e-06	2	82	2	34653248
Pubmed	Phenolic acids suppress adipocyte lipolysis via activation of the nicotinic acid receptor GPR109A (HM74a/PUMA-G).	HCAR3 HCAR2	5.49e-06	2	82	2	19136666
Pubmed	Meta-analysis of genome-wide studies identifies WNT16 and ESR1 SNPs associated with bone mineral density in premenopausal women.	ESR1 WNT16	5.49e-06	2	82	2	23074152
Pubmed	G Protein-Coupled Receptor 109A Maintains the Intestinal Integrity and Protects Against ETEC Mucosal Infection by Promoting IgA Secretion.	HCAR3 HCAR2	5.49e-06	2	82	2	33488584
Pubmed	Lactate-induced activation of HCA2 improves survival in mice with sepsis.	HCAR3 HCAR2	5.49e-06	2	82	2	30951370
Pubmed	Collapse of the keratin filament network through the expression of mutant keratin 6c observed in a case of focal plantar keratoderma.	KRT6A KRT6C	5.49e-06	2	82	2	23662636
Pubmed	Niacin Ameliorates Hepatic Steatosis by Inhibiting De Novo Lipogenesis Via a GPR109A-Mediated PKC-ERK1/2-AMPK Signaling Pathway in C57BL/6 Mice Fed a High-Fat Diet.	HCAR3 HCAR2	5.49e-06	2	82	2	31858105
Pubmed	Deficiency of metabolite sensing receptor HCA2 impairs the salutary effect of niacin in hemorrhagic shock.	HCAR3 HCAR2	5.49e-06	2	82	2	30625381
Pubmed	Exploring the role of the metabolite-sensing receptor GPR109a in diabetic nephropathy.	HCAR3 HCAR2	5.49e-06	2	82	2	32068460
Pubmed	The activation of retinal HCA2 receptors by systemic beta-hydroxybutyrate inhibits diabetic retinal damage through reduction of endoplasmic reticulum stress and the NLRP3 inflammasome.	HCAR3 HCAR2	5.49e-06	2	82	2	30657794
Pubmed	Ketones and pain: unexplored role of hydroxyl carboxylic acid receptor type 2 in the pathophysiology of neuropathic pain.	HCAR3 HCAR2	5.49e-06	2	82	2	30085883
Pubmed	Nicotinic acid receptor abnormalities in human skin cancer: implications for a role in epidermal differentiation.	HCAR3 HCAR2	5.49e-06	2	82	2	21655214
Pubmed	Melatonin alleviates titanium nanoparticles induced osteolysis via activation of butyrate/GPR109A signaling pathway.	HCAR3 HCAR2	5.49e-06	2	82	2	34092246
Pubmed	(D)-beta-Hydroxybutyrate inhibits adipocyte lipolysis via the nicotinic acid receptor PUMA-G.	HCAR3 HCAR2	5.49e-06	2	82	2	15929991
Pubmed	Discovery of a novel murine keratin 6 (K6) isoform explains the absence of hair and nail defects in mice deficient for K6a and K6b.	KRT6A KRT6B	5.49e-06	2	82	2	11489919
Pubmed	Activation of HCA2 regulates microglial responses to alleviate neurodegeneration in LPS-induced in vivo and in vitro models.	HCAR3 HCAR2	5.49e-06	2	82	2	36991440
Pubmed	Inflammation stimulates niacin receptor (GPR109A/HCA2) expression in adipose tissue and macrophages.	HCAR3 HCAR2	5.49e-06	2	82	2	25320346
Pubmed	Molecular identification of high and low affinity receptors for nicotinic acid.	HCAR3 HCAR2	5.49e-06	2	82	2	12522134
Pubmed	Delayed wound healing in keratin 6a knockout mice.	KRT6A KRT6B	5.49e-06	2	82	2	10866680
Pubmed	Introducing a null mutation in the mouse K6alpha and K6beta genes reveals their essential structural role in the oral mucosa.	KRT6A KRT6B	5.49e-06	2	82	2	10953016
Pubmed	The complete cDNA and deduced amino acid sequence of a type II mouse epidermal keratin of 60,000 Da: analysis of sequence differences between type I and type II keratins.	KRT6A KRT6B	5.49e-06	2	82	2	6207530
Pubmed	Nicotinic acid inhibits glucose-stimulated insulin secretion via the G protein-coupled receptor PUMA-G in murine islet β cells.	HCAR3 HCAR2	5.49e-06	2	82	2	21441844
Pubmed	G Protein-Coupled Receptor 109A and Host Microbiota Modulate Intestinal Epithelial Integrity During Sepsis.	HCAR3 HCAR2	5.49e-06	2	82	2	30271409
Pubmed	Niacin fine-tunes energy homeostasis through canonical GPR109A signaling.	HCAR3 HCAR2	5.49e-06	2	82	2	30596513
Pubmed	The niacin receptor HCAR2 modulates microglial response and limits disease progression in a mouse model of Alzheimer's disease.	HCAR3 HCAR2	5.49e-06	2	82	2	35320002
Pubmed	GPR109A (PUMA-G/HM74A) mediates nicotinic acid-induced flushing.	HCAR3 HCAR2	5.49e-06	2	82	2	16322797
Pubmed	BHBA treatment improves cognitive function by targeting pleiotropic mechanisms in transgenic mouse model of Alzheimer's disease.	HCAR3 HCAR2	5.49e-06	2	82	2	31914599
Pubmed	Cytokeratins mediate epithelial innate defense through their antimicrobial properties.	KRT6A KRT6B	5.49e-06	2	82	2	23006328
Pubmed	Nicotinic acid receptor agonists.	HCAR3 HCAR2	5.49e-06	2	82	2	18983141
Pubmed	Gut microbial metabolite butyrate protects against proteinuric kidney disease through epigenetic- and GPR109a-mediated mechanisms.	HCAR3 HCAR2	5.49e-06	2	82	2	31366236
Pubmed	Modulation of HDL metabolism by the niacin receptor GPR109A in mouse hepatocytes.	HCAR3 HCAR2	5.49e-06	2	82	2	20655299
Pubmed	Evidence for constitutive dimerization of niacin receptor subtypes.	HCAR3 HCAR2	5.49e-06	2	82	2	20380810
Pubmed	GPR109A Expression in the Murine Min6 Pancreatic Beta Cell Line, and Its Relation with Glucose Metabolism and Inflammation.	HCAR3 HCAR2	5.49e-06	2	82	2	26116596
Pubmed	Expression and activation of the ketone body receptor HCAR2/GPR109A promotes preservation of retinal endothelial cell barrier function.	HCAR3 HCAR2	5.49e-06	2	82	2	35649469
Pubmed	GPR109A expressed on medullary thymic epithelial cells affects thymic Treg development.	HCAR3 HCAR2	5.49e-06	2	82	2	37595951
Pubmed	The hypophagic response to heat stress is not mediated by GPR109A or peripheral β-OH butyrate.	HCAR3 HCAR2	5.49e-06	2	82	2	26936786
Pubmed	Hydroxycarboxylic Acid Receptor 2, a Pleiotropically Linked Receptor for the Multiple Sclerosis Drug, Monomethyl Fumarate. Possible Implications for the Inflammatory Response.	HCAR3 HCAR2	5.49e-06	2	82	2	34084164
Pubmed	PARP7 and Mono-ADP-Ribosylation Negatively Regulate Estrogen Receptor α Signaling in Human Breast Cancer Cells.	ESR1 TIPARP	5.49e-06	2	82	2	33799807
Pubmed	GPR109A gene deletion ameliorates gonadectomy-induced bone loss in mice.	HCAR3 HCAR2	5.49e-06	2	82	2	35489706
Pubmed	Deorphanization of GPR109B as a receptor for the beta-oxidation intermediate 3-OH-octanoic acid and its role in the regulation of lipolysis.	HCAR3 HCAR2	5.49e-06	2	82	2	19561068
Pubmed	A comprehensive resource of interacting protein regions for refining human transcription factor networks.	TAOK3 SEC62 SYTL2 APLP2 RPL35 ARHGAP21	6.28e-06	191	82	6	20195357
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	DDX47 CDC37 KIFBP LMO7 HLA-DPB1 POLD1 SEC62 NAT10 MCM5 SRPRA CTNNA1 PRPF8 HEATR3 KPNA3	6.43e-06	1440	82	14	30833792
Pubmed	Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.	CDC37 PAXBP1 LMO7 POLD1 MATN2 NAT10 MCM5 CTNNA1 RPL35 PRPF8 AXIN2 RPL18 KPNA3	6.82e-06	1247	82	13	27684187
Pubmed	TRIM28-mediated nucleocapsid protein SUMOylation enhances SARS-CoV-2 virulence.	DDX47 KRT6A KRT6B AMOT NAT10 MCM5 RPL35 RPL18	8.20e-06	430	82	8	38172120
Pubmed	LukS-PV inhibits hepatocellular carcinoma cells migration by downregulating HDAC6 expression.	KRT6A KRT6B LMO7 NAT10 MCM5 SRPRA RPL35 PLA2G4E RPL18	9.32e-06	580	82	9	35676659
Pubmed	Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.	DDX47 KIFBP LMO7 POLD1 NAT10 MCM5 CTNNA1 PRPF8 USP48	9.58e-06	582	82	9	20467437
Pubmed	Adenomatous polyposis coli (APC) is required for normal development of skin and thymus.	KRT6A KRT6B AXIN2	1.19e-05	19	82	3	17002498
Pubmed	BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.	DDX47 CDC37 KRT6B TAOK3 PAXBP1 POLD1 NAT10 MCM5 SRPRA RPL35 NKAP PRPF8 RPL18	1.23e-05	1318	82	13	30463901
Pubmed	Intrinsically Disordered Protein TEX264 Mediates ER-phagy.	LMO7 SEC62 HEATR3 RPL18 KPNA3	1.52e-05	131	82	5	31006538
Pubmed	Keratin expression provides novel insight into the morphogenesis and function of the companion layer in hair follicles.	KRT6A KRT6B	1.64e-05	3	82	2	17170733
Pubmed	Hyperhomocysteinemia is detrimental to pregnancy in mice and is associated with preterm birth.	HCAR3 HCAR2	1.64e-05	3	82	2	23579073
Pubmed	Short-chain fatty acids directly exert anti-inflammatory responses in podocytes and tubular epithelial cells exposed to high glucose.	HCAR3 HCAR2	1.64e-05	3	82	2	37215085
Pubmed	Colonic gene expression in conventional and germ-free mice with a focus on the butyrate receptor GPR109A and the butyrate transporter SLC5A8.	HCAR3 HCAR2	1.64e-05	3	82	2	20033346
Pubmed	Overcoming functional redundancy to elicit pachyonychia congenita-like nail lesions in transgenic mice.	KRT6A KRT6B	1.64e-05	3	82	2	15601842
Pubmed	Cytokeratin 5/6 expression in bladder cancer: association with clinicopathologic parameters and prognosis.	KRT6A KRT6B	1.64e-05	3	82	2	29587848
Pubmed	Niacin stimulates adiponectin secretion through the GPR109A receptor.	HCAR3 HCAR2	1.64e-05	3	82	2	19141678
Pubmed	International Union of Basic and Clinical Pharmacology. LXXXII: Nomenclature and Classification of Hydroxy-carboxylic Acid Receptors (GPR81, GPR109A, and GPR109B).	HCAR3 HCAR2	1.64e-05	3	82	2	21454438
Pubmed	A role for keratins in supporting mitochondrial organization and function in skin keratinocytes.	KRT6A KRT6B	1.64e-05	3	82	2	32213122
Pubmed	Nicotinic acid- and monomethyl fumarate-induced flushing involves GPR109A expressed by keratinocytes and COX-2-dependent prostanoid formation in mice.	HCAR3 HCAR2	1.64e-05	3	82	2	20664170
Pubmed	Metabolites produced by commensal bacteria promote peripheral regulatory T-cell generation.	HCAR3 HCAR2	1.64e-05	3	82	2	24226773
Pubmed	Activation of microglial GPR109A alleviates thermal hyperalgesia in female lupus mice by suppressing IL-18 and glutamatergic synaptic activity.	HCAR3 HCAR2	1.64e-05	3	82	2	34919284
Pubmed	Induction of the cystine/glutamate exchanger SLC7A11 in retinal pigment epithelial cells by the antipsoriatic drug monomethylfumarate.	HCAR3 HCAR2	1.64e-05	3	82	2	23404113
Pubmed	Niacin receptor GPR109A inhibits insulin secretion and is down-regulated in type 2 diabetic islet beta-cells.	HCAR3 HCAR2	1.64e-05	3	82	2	27570060
Pubmed	The β-hydroxybutyrate receptor HCA2 activates a neuroprotective subset of macrophages.	HCAR3 HCAR2	1.64e-05	3	82	2	24845831
Pubmed	Dopamine D3 receptor inhibits the ubiquitin-specific peptidase 48 to promote NHE3 degradation.	SLC9A3 USP48	1.64e-05	3	82	2	24308971
Interaction	TOP2A interactions	CDC37 KIFBP ZMYND11 POLD1 ESR1 CAPN2 MCM5 RPL35 PRPF8 TIPARP RPL18 KPNA3	7.09e-07	520	78	12	int:TOP2A
Interaction	TFIP11 interactions	FAM50B KRT6A KRT6B ZMYND11 LIN37 PAXBP1 KRT6C ESR1 PRPF8 TIPARP LSM3	7.38e-07	427	78	11	int:TFIP11
Interaction	CHD3 interactions	DDX47 KRT6A KRT6B LIN37 CDK2AP2 PAXBP1 KRT6C NAT10 MCM5 RPL35 PRPF8 TIPARP RPL18 KPNA3	1.09e-06	757	78	14	int:CHD3
Interaction	CHMP4B interactions	DDX47 LMO7 POLD1 ESR1 NAT10 CC2D1B MCM5 SRPRA RPL35 PRPF8 ARHGAP21 TIPARP RPL18	3.99e-06	727	78	13	int:CHMP4B
Interaction	EFTUD2 interactions	DDX47 KRT6A KRT6B KIFBP ZMYND11 PAXBP1 KRT6C POLD1 ESR1 CAPN2 MCM5 SRPRA CTNNA1 RPL35 PRPF8 TIPARP LSM3 RPL18	7.94e-06	1449	78	18	int:EFTUD2
Interaction	CHD4 interactions	DDX47 KRT6A KRT6B LIN37 CDK2AP2 PAXBP1 KRT6C ESR1 CAPN2 NAT10 RPL35 PRPF8 TIPARP RPL18	1.29e-05	938	78	14	int:CHD4
Interaction	HNRNPA1 interactions	CDC37 KRT6A KRT6B KRT6C ESR1 CAPN2 NAT10 SYTL2 MAST1 MCM5 PRPF8 USP48 HEATR3 TIPARP	1.40e-05	945	78	14	int:HNRNPA1
Interaction	NAT10 interactions	ZMYND11 ESR1 NAT10 MAST1 MCM5 RPL35 GRAMD4 TIPARP	2.19e-05	302	78	8	int:NAT10
Interaction	CTNNB1 interactions	EPHB2 CDC37 LMO7 AMOT ESR1 SEC62 EPB41L5 MAST1 MCM5 CTNNA1 USP48 ARHGAP21 AXIN2 RPL18	2.90e-05	1009	78	14	int:CTNNB1
Interaction	CWC27 interactions	ESR1 EPB41L5 PRPF8 TIPARP LSM3	4.31e-05	100	78	5	int:CWC27
Interaction	EFNA1 interactions	EPHB2 KRT6A KRT6B EPHA6 KRT6C	4.97e-05	103	78	5	int:EFNA1
Interaction	KRT8 interactions	KRT6A KRT6B KIFBP DCDC1 KRT6C ESR1 PRPF8 ARHGAP21 PDZRN3	5.08e-05	441	78	9	int:KRT8
Interaction	PQBP1 interactions	PAXBP1 POLD1 ESR1 PRPF8 TIPARP	5.44e-05	105	78	5	int:PQBP1
Interaction	KIFC3 interactions	CDC37 KRT6A KRT6B LIN37 KRT6C CC2D1B AXIN2	5.46e-05	252	78	7	int:KIFC3
Interaction	NAP1L1 interactions	ESR1 EPB41L5 CTNNA1 RPL35 PRPF8 USP48 TIPARP RPL18	5.62e-05	345	78	8	int:NAP1L1
Interaction	PHTF1 interactions	KRT6A KRT6B KRT6C	6.06e-05	20	78	3	int:PHTF1
Interaction	KRT75 interactions	CDC37 KRT6A KRT6B KRT6C AMOT PRPF8	7.26e-05	181	78	6	int:KRT75
Interaction	SRRM2 interactions	ZMYND11 POLD1 ESR1 MATN2 MAST1 NKAP PRPF8 TIPARP LSM3	7.27e-05	462	78	9	int:SRRM2
Interaction	G3BP1 interactions	DDX47 CDC37 ZMYND11 ESR1 CC2D1B MCM5 SRPRA RPL35 PRPF8 TIPARP LSM3 RPL18	8.29e-05	835	78	12	int:G3BP1
Interaction	NT5C2 interactions	KIFBP ESR1 EPB41L5 PRPF8 KPNA3	9.11e-05	117	78	5	int:NT5C2
Interaction	PAXBP1 interactions	PAXBP1 GPATCH3 ESR1 PRPF8 LSM3	1.07e-04	121	78	5	int:PAXBP1
Interaction	GRAMD4 interactions	POLD1 SEC62 NAT10 GRAMD4	1.11e-04	64	78	4	int:GRAMD4
Interaction	CSK interactions	EPHB2 CDC37 SEMA3D AMOT CAPN2 MAST1 CTNNA1 DDHD2 ITPRID1 CFI PDZRN3 TIPARP	1.11e-04	861	78	12	int:CSK
Interaction	RPL5 interactions	FAM50B ESR1 NAT10 SRPRA RPL35 PRPF8 USP48 HEATR3 TIPARP RPL18	1.12e-04	606	78	10	int:RPL5
Interaction	USP42 interactions	AMOT POLD1 TIPARP KPNA3	1.25e-04	66	78	4	int:USP42
Interaction	SEPTIN3 interactions	EPHB2 CDC37 ESR1 SEPTIN14	1.25e-04	66	78	4	int:SEPTIN3
Interaction	TJP2 interactions	LMO7 AMOT EPB41L5 CTNNA1 ARHGAP21 TIPARP RPL18	1.26e-04	288	78	7	int:TJP2
Interaction	DCTN1 interactions	CDC37 KRT6A KRT6B DCDC1 KRT6C SEPTIN14 CC2D1B USP48 ARHGAP21	1.27e-04	497	78	9	int:DCTN1
Interaction	PARP1 interactions	CDC37 KIFBP ASRGL1 LMO7 POLD1 ESR1 CAPN2 NAT10 MCM5 CTNNA1 RPL35 PRPF8 USP48 TIPARP KPNA3	1.37e-04	1316	78	15	int:PARP1
Interaction	GPATCH3 interactions	PAXBP1 GPATCH3	1.47e-04	5	78	2	int:GPATCH3
Interaction	SART3 interactions	DDX47 AMOT ESR1 PRPF8 TIPARP LSM3 RPL18	1.49e-04	296	78	7	int:SART3
Interaction	SNRPE interactions	CDC37 PAXBP1 ESR1 CAPN2 PRPF8 TIPARP LSM3	1.79e-04	305	78	7	int:SNRPE
Interaction	PRPF8 interactions	CDC37 KRT6A KRT6B KIFBP ZMYND11 PAXBP1 ESR1 MCM5 PRPF8 TIPARP RPL18	1.90e-04	776	78	11	int:PRPF8
Interaction	KRT36 interactions	KRT6A KRT6B KRT6C AMOT	1.95e-04	74	78	4	int:KRT36
Interaction	RPL11 interactions	KIFBP ESR1 EPB41L5 RPL35 PRPF8 USP48 HEATR3 TIPARP RPL18 KPNA3	2.03e-04	652	78	10	int:RPL11
Interaction	NOP2 interactions	DDX47 ESR1 NAT10 MCM5 ZNF317 PRPF8 TIPARP RPL18	2.05e-04	416	78	8	int:NOP2
Interaction	KRT28 interactions	KRT6A KRT6B KRT6C	2.10e-04	30	78	3	int:KRT28
Interaction	KRT18 interactions	KRT6A KRT6B KRT6C ESR1 MCM5 CTNNA1 PRPF8 PDZRN3	2.15e-04	419	78	8	int:KRT18
Interaction	RBM19 interactions	ESR1 NAT10 MAST1 RPL35 TIPARP RPL18	2.16e-04	221	78	6	int:RBM19
Interaction	FBXO22 interactions	DDX47 TAOK3 LMO7 POLD1 ESR1 SRPRA CTNNA1 PRPF8 ARHGAP21	2.35e-04	540	78	9	int:FBXO22
Interaction	SRP9 interactions	ESR1 MAST1 SRPRA RPL35 PRPF8 HEATR3 TIPARP RPL18	2.44e-04	427	78	8	int:SRP9
Interaction	TRIM54 interactions	FAM50B EPHB2 CDC37 KRT6A KRT6B LIN37 KRT6C	2.45e-04	321	78	7	int:TRIM54
Interaction	PCBP1 interactions	CDC37 POLD1 ESR1 NAT10 MCM5 PRPF8 USP48 TIPARP RPL18 KPNA3	2.56e-04	671	78	10	int:PCBP1
Interaction	KRT7 interactions	KRT6A KRT6B KRT6C PRPF8	2.63e-04	80	78	4	int:KRT7
Interaction	TJP1 interactions	LMO7 AMOT BRSK2 GJC1 EPB41L5 CTNNA1 TIPARP	2.64e-04	325	78	7	int:TJP1
Interaction	BRCA1 interactions	CDC37 POLD1 ESR1 NAT10 MCM5 APLP2 CTNNA1 RPL35 USP48 ARHGAP21 FAM83A TIPARP RPL18 KPNA3	2.80e-04	1249	78	14	int:BRCA1
Interaction	DDRGK1 interactions	DDX47 KRT6B PAXBP1 ESR1 SEC62 NAT10 MCM5 SRPRA RPL35 NKAP PRPF8 HEATR3 LSM3 RPL18	2.80e-04	1249	78	14	int:DDRGK1
Interaction	BOD1L1 interactions	KIFBP EPB41L5 PRPF8 TIPARP KPNA3	2.83e-04	149	78	5	int:BOD1L1
Interaction	AFDN interactions	EPHB2 ESR1 SEC62 EPB41L5 CTNNA1 ARHGAP21 TIPARP	3.05e-04	333	78	7	int:AFDN
Interaction	DDX18 interactions	DDX47 ESR1 NAT10 MAST1 RPL35 TIPARP RPL18	3.11e-04	334	78	7	int:DDX18
Interaction	SFN interactions	LMO7 AMOT POLD1 ESR1 EPB41L5 APLP2 RPL35 PRPF8 ARHGAP21 RPL18	3.27e-04	692	78	10	int:SFN
Interaction	EFNA4 interactions	KRT6A KRT6B EPHA6 KRT6C RUNDC1 HEATR3	3.29e-04	239	78	6	int:EFNA4
Interaction	KRT26 interactions	KRT6A KRT6B KRT6C	3.34e-04	35	78	3	int:KRT26
Interaction	KRT25 interactions	KRT6A KRT6B KRT6C	3.34e-04	35	78	3	int:KRT25
Interaction	DDX39B interactions	CDC37 KRT6A KRT6B KRT6C LMO7 PRPF8 USP48 TIPARP RPL18	3.50e-04	570	78	9	int:DDX39B
Interaction	KRT31 interactions	FAM50B KRT6A KRT6B LIN37 KRT6C AMOT TCEAL8 PRPF8	3.63e-04	453	78	8	int:KRT31
Interaction	CALM3 interactions	EPHB2 EPHA6 LMO7 AMOT ESR1 USP48 ARHGAP21	3.65e-04	343	78	7	int:CALM3
Interaction	RPL10 interactions	DDX47 ZMYND11 ESR1 MATN2 NAT10 SRPRA RPL35 PRPF8 TIPARP RPL18	3.66e-04	702	78	10	int:RPL10
Interaction	OFD1 interactions	CDC37 KIFBP AMOT CAPN2 PDZRN3 DRC3 CHST3	3.91e-04	347	78	7	int:OFD1
Interaction	CT45A10 interactions	POLD1 ESR1	4.08e-04	8	78	2	int:CT45A10
Interaction	NOL10 interactions	DDX47 ESR1 NAT10 RPL35 TIPARP	4.15e-04	162	78	5	int:NOL10
Interaction	CDC5L interactions	DDX47 PAXBP1 LMO7 POLD1 ESR1 NAT10 MAST1 MCM5 CTNNA1 PRPF8 TIPARP	4.35e-04	855	78	11	int:CDC5L
Interaction	GNL1 interactions	KIFBP PRPF8 TIPARP KPNA3	4.48e-04	92	78	4	int:GNL1
Interaction	RPL3 interactions	ESR1 MATN2 NAT10 EPB41L5 RPL35 ZNF317 PRPF8 USP48 TIPARP RPL18	4.57e-04	722	78	10	int:RPL3
Interaction	RBM8A interactions	DDX47 ESR1 CAPN2 SRPRA RPL35 PRPF8 LSM3 RPL18	4.83e-04	473	78	8	int:RBM8A
Interaction	FNTA interactions	HEYL CAPN2 EPB41L5 RPL18	4.86e-04	94	78	4	int:FNTA
Interaction	PPP6R3 interactions	CDC37 KIFBP ESR1 BRSK2 EPB41L5 TIPARP	4.94e-04	258	78	6	int:PPP6R3
Cytoband	12q13.13	KRT6A KRT6B KRT6C	2.42e-04	67	82	3	12q13.13
GeneFamily	Hydroxy-carboxylic acid receptors	HCAR3 HCAR2	2.43e-05	3	52	2	200
GeneFamily	Keratins, type II	KRT6A KRT6B KRT6C	6.25e-05	27	52	3	609
GeneFamily	Fibronectin type III domain containing\|Sterile alpha motif domain containing\|EPH receptors	EPHB2 EPHA6	7.22e-04	14	52	2	1095
GeneFamily	PDZ domain containing	LMO7 MAST1 ARHGAP21 PDZRN3	9.50e-04	152	52	4	1220
GeneFamily	Zinc fingers MYND-type	SMYD4 ZMYND11	1.65e-03	21	52	2	87
GeneFamily	Sterile alpha motif domain containing	EPHB2 EPHA6 DDHD2	2.07e-03	88	52	3	760
ToppCell	Tracheal-NucSeq-Stromal-Schwann-Schwann_Myelinating\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	HEYL SLC9A3 CDK2AP2 GPATCH3 BRSK2 CC2D1B CHST3	8.56e-08	199	82	7	4e4bdcd2e8b518156d5ebd294804180acaa3566b
ToppCell	TCGA-Head_and_Esophagus\|World / Sample_Type by Project: Shred V9	KRT6A KRT6B HCAR2 KRT6C PLA2G4E FAM83A	7.87e-07	172	82	6	eb18aa179db1818f408c38e442ecfed8582d7dbc
ToppCell	facs-GAT-Fat-3m\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT6A MATN2 CAPN2 APLP2 CTNNA1 TIPARP	1.41e-06	190	82	6	1d92be1b41cff59e834a9d28868f554bd1f3e471
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_2_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	EPHB2 SEMA3D ESR1 MATN2 ARHGAP21 PDZRN3	1.49e-06	192	82	6	8d56e360ebc624ca4cd7f0af4f3cc599c244f134
ToppCell	(01)_IL1RL1+-(1)_GFP\|(01)_IL1RL1+ / shred by cell type by condition	KRT6A KRT6B CAPN2 APLP2 FAM83A B4GALT1	1.68e-06	196	82	6	b598b1112242534e139318012b257ed3cb09da83
ToppCell	facs-Skin-Telogen-3m-Epithelial-outer_bulge\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT6A ENOX1 LMO7 CAPN2 APLP2 PDZRN3	1.68e-06	196	82	6	c936014125b2ed5f796221b74acb77b8f8359875
ToppCell	facs-Lung-Endomucin-24m-Lymphocytic-CD8-positive,_alpha-beta_T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SMYD4 CDK2AP2 RPL35 GRAMD4 RPL18	1.52e-05	169	82	5	2ad6ab74788c8738c9087811688a6128e5fa882a
ToppCell	facs-Lung-Endomucin-24m-Lymphocytic-CD8+_T\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SMYD4 CDK2AP2 RPL35 GRAMD4 RPL18	1.52e-05	169	82	5	3e608377b57e7f309d243467668c50abb499fcfe
ToppCell	368C-Myeloid-Macrophage-SPP1+_Macrophage_2\|368C / Donor, Lineage, Cell class and subclass (all cells)	KIFBP ZMYND11 LIN37 PIEZO1 CC2D1B	1.61e-05	171	82	5	26b34dc069cc15b75a0c13cb8c5d81e074788160
ToppCell	TCGA-Bladder-Primary_Tumor-Urothelial_Carcinoma-Non-Papillary_Muscle_Invasive_Urothelial_Carcinoma-6\|TCGA-Bladder / Sample_Type by Project: Shred V9	KRT6A KRT6B KRT6C PLA2G4E FAM83A	1.61e-05	171	82	5	0e78389f8f3d54570a6deb3dd307b865b46307e9
ToppCell	NS-critical-d_16-33-Epithelial-Basal\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	KRT6A ASRGL1 KRT6C RPL35 RPL18	1.70e-05	173	82	5	3d3afc9ab234eaabf5b9bff455406231cd54ded6
ToppCell	Children_(3_yrs)-Mesenchymal-vascular_smooth_muscle_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	HEYL ENOX1 SYTL2 GJC1 PDZRN3	1.70e-05	173	82	5	5416b092321c7d9b63f0418c60f2402a138355bf
ToppCell	Fetal_29-31_weeks-Mesenchymal-vascular_smooth_muscle_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	HEYL ENOX1 SYTL2 GJC1 THSD7B	1.95e-05	178	82	5	066dbc4cc2083c549d98122ed44707127f34d582
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Degenerative_Cortical_Thick_Ascending_Limb_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FAM50B CDK2AP2 APLP2 RPL35 RPL18	2.06e-05	180	82	5	58653238780cd5ce6d086c444f4afa897d9db10b
ToppCell	TCGA-Skin-Primary_Tumor-Melanoma-Skin_Cutaneous_Melanoma-6\|TCGA-Skin / Sample_Type by Project: Shred V9	KRT6A KRT6B KRT6C PLA2G4E FAM83A	2.48e-05	187	82	5	2ca7928baf0c5e61f7294ed05e6e6f0e0adf9d3f
ToppCell	TCGA-Cervix-Primary_Tumor-Cervical_Carcinoma\|TCGA-Cervix / Sample_Type by Project: Shred V9	HCAR3 KRT6A KRT6B HCAR2 KRT6C	2.60e-05	189	82	5	533c302df467d13ab639232daf4f8cafb808260b
ToppCell	TCGA-Skin-Primary_Tumor-Melanoma-Skin_Cutaneous_Melanoma\|TCGA-Skin / Sample_Type by Project: Shred V9	KRT6A KRT6B KRT6C PLA2G4E FAM83A	2.67e-05	190	82	5	3188c7bd225cbcf46a21e2fb784336cdd9665995
ToppCell	TCGA-Skin-Primary_Tumor\|TCGA-Skin / Sample_Type by Project: Shred V9	KRT6A KRT6B KRT6C PLA2G4E FAM83A	2.67e-05	190	82	5	e2b26a03c6ab24d9b0f4150c47597be37767d86e
ToppCell	TCGA-Skin-Primary_Tumor-Melanoma\|TCGA-Skin / Sample_Type by Project: Shred V9	KRT6A KRT6B KRT6C PLA2G4E FAM83A	2.67e-05	190	82	5	01fb45add4661bc86cd0a34fac35177907152dbb
ToppCell	Mesenchymal-vascular_smooth_muscle_cell\|World / Lineage, Cell type, age group and donor	HEYL ENOX1 SYTL2 GJC1 PDZRN3	2.74e-05	191	82	5	fd89fbc62aa1c73e0f659991e3bd726a0c97bd68
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_2_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	EPHB2 SEMA3D ESR1 ARHGAP21 PDZRN3	2.95e-05	194	82	5	439d3f17c1f4736122b330e98add9292c7036a8e
ToppCell	facs-Skin-Anagen-3m-Epithelial-outer_bulge\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT6A MATN2 CAPN2 APLP2 PDZRN3	2.95e-05	194	82	5	5d30d3d41d5f19cdf3077cc609aa2738762cb8c5
ToppCell	facs-Skin-Telogen-3m-Epithelial-bulge_keratinocyte\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT6A LMO7 CAPN2 APLP2 PDZRN3	3.10e-05	196	82	5	90edf61116ffcb4f8b6be3d0a05732d59b0a87d5
ToppCell	Epithelial-Epithelial-A_(AT1)\|Epithelial / shred on cell class and cell subclass (v4)	DDX47 LMO7 CAPN2 CTNNA1 PDZRN3	3.10e-05	196	82	5	41b21a18125cc95bc8adde3369e4abd029cf137d
ToppCell	5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ASRGL1 LMO7 SYTL2 CTNNA1 FAM83A	3.18e-05	197	82	5	adb4e27d73ae2e6a39d212c0ead3ac0ad62d9131
ToppCell	(02)_MMP9/10+-(1)_GFP\|(02)_MMP9/10+ / shred by cell type by condition	EPHB2 KRT6A KRT6B PIEZO1 B4GALT1	3.33e-05	199	82	5	448ba982be804007f991d469eca9d885b21ae499
ToppCell	10x5'v1-week_14-16-Myeloid_monocytic-monocyte-promonocyte\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	ASRGL1 PIEZO1 CAPN2 APLP2 RPL35	3.33e-05	199	82	5	f7661a386224682e1d79cc9949204d05c0dfe324
ToppCell	Lung_Parenchyma-Severe-Epithelial-Epithelial-Basal_2\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	KRT6A KRT6B KRT6C LMO7 FAM83A	3.41e-05	200	82	5	c7668e26c6b8cfa6d174b0634e43c230425faba9
ToppCell	Parenchyma_COVID-19-Epithelial-TX-Basal_2\|Parenchyma_COVID-19 / Sample group, Lineage and Cell type	KRT6A KRT6B KRT6C LMO7 FAM83A	3.41e-05	200	82	5	bce9bce9eb622bc6514708d49ca4a6604043c22a
ToppCell	5'-Airway_Nasal\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	KRT6A ASRGL1 LMO7 SYTL2 CTNNA1	3.41e-05	200	82	5	f6e967738b4f7b173d6e9977e305f77380dd6c8a
ToppCell	Lung_Parenchyma-Severe-Epithelial-Epithelial-Basal_2-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	KRT6A KRT6B KRT6C LMO7 FAM83A	3.41e-05	200	82	5	621dd6438ef6e71811d3644b75209535b7c0f8f7
ToppCell	mLN-B_cell-Follicular_B_cell\|B_cell / Region, Cell class and subclass	HLA-DPB1 SEC62 APLP2 RPL35 RPL18	3.41e-05	200	82	5	8fbd27ffcfd0702ad3c340d32455e36a01617139
ToppCell	5'-Airway_Nasal-Epithelial\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	KRT6A ASRGL1 LMO7 SYTL2 CTNNA1	3.41e-05	200	82	5	358d71329921451c7f5a56f1db0f9989af2299dc
ToppCell	droplet-Skin-nan-18m\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT6A KRT6B CAPN2 PLA2G4E	8.40e-05	125	82	4	5a309ce803d2b8efd791eb21808121bf5fc3ea8e
ToppCell	droplet-Skin-nan-18m-Epithelial-epidermal_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT6A KRT6B HCAR2 PLA2G4E	9.78e-05	130	82	4	4c8b931987432e8bcd39029d4fa124dc383ea355
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c02-GPR183\|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)	SYTL2 EPB41L5 PLA2G4E C2orf81	1.20e-04	137	82	4	0c82f815c014d01213d23b466043d6e57186dceb
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FAM50B ENOX1 EPHA6 MAST1	1.49e-04	145	82	4	b961b69befb15ff6f58635e0d4bda88ea732a346
ToppCell	10x_3'_v3-tissue-resident_(10x_3'_v3)-myeloid-myeloid_dendritic-liver_dendritic_cell\|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	ENOX1 DCDC1 HLA-DPB1 CFI	1.97e-04	156	82	4	411c170a7dd65269ae442b8069caf5231bddb116
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Outer_Medullary_Collecting_Duct_Intercalated_Cell_Type_A\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	HCAR3 HCAR2 ESR1 THSD7B	2.17e-04	160	82	4	174a4ab27114efcc63be36929b80680be3c35c9b
ToppCell	10x5'-bone_marrow-Myeloid_Dendritic-DC1\|bone_marrow / Manually curated celltypes from each tissue	ENOX1 HLA-DPB1 SEPTIN14 CFI	2.22e-04	161	82	4	2f068ee643de2f647c289779a6624265ab9a749b
ToppCell	facs-Mammary_Gland-Mammary_Gland-18m-Epithelial-nan\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT6A KRT6B HCAR2 ESR1	2.22e-04	161	82	4	b9a63fc9becc44d305fc7c221283bf59ec06b10f
ToppCell	ILEUM-non-inflamed-(2)_B_cell-(2)_Naive_B_cells\|(2)_B_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	SEC62 APLP2 RPL35 RPL18	2.33e-04	163	82	4	9add806d706f7170a49b2c2dcc14343e9befd26c
ToppCell	Children_(3_yrs)-Mesenchymal-vascular_smooth_muscle_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	HEYL SYTL2 GJC1 CHST3	2.44e-04	165	82	4	8a82e20c9b1156bb4bbc16f7785abb04458d671b
ToppCell	NS-critical-d_0-4-Myeloid-Monocyte-derived_DC\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	HLA-DPB1 ESR1 RPL35 LSM3	2.67e-04	169	82	4	6fe82db874eff0f86e5c0d1cc81322eb9d7874eb
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-mesothelial_cell\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SEMA3D HCAR2 CFI AXIN2	2.67e-04	169	82	4	0cece9b2bb1f58e465c20ec8735a4fc3c1021f03
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-mesothelial_cell-Mesothelium\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SEMA3D HCAR2 CFI AXIN2	2.67e-04	169	82	4	6937c46b119d4ce382fc8c2fa5925ede5ae89c81
ToppCell	droplet-Skin-nan-18m-Epithelial-keratinocyte_stem_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT6A KRT6B GJC1 PDZRN3	2.74e-04	170	82	4	10e0912dd0beab5d0bbe2bd49e477b5962687925
ToppCell	droplet-Lung-21m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l48\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GPATCH3 NAT10 USP48 CHST3	2.74e-04	170	82	4	070d8683d1a5cc7d594ff0453c961a9bf982c2d0
ToppCell	TCGA-Cervix\|World / Sample_Type by Project: Shred V9	KRT6A POLD1 MCM5 FAM83A	2.74e-04	170	82	4	a6cbe253bc60f5d5cb361c7e85ed9928a3155ec8
ToppCell	facs\|World / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HEYL MAST1 DDHD2 B4GALT1	2.86e-04	172	82	4	a2d0a64ebf09d219a07d6bbad1056bad6d46b9be
ToppCell	Adult-Mesenchymal-pericyte_cell-D231\|Adult / Lineage, Cell type, age group and donor	HEYL ENOX1 GJC1 PDZRN3	2.86e-04	172	82	4	858cee96c1c06160863b4adcd7023c0d678bd50f
ToppCell	(00)_Basal-(1)_24hpi\|(00)_Basal / shred by cell type and Timepoint	KRT6A KRT6B MCM5 TIPARP	2.92e-04	173	82	4	a8e62e7d8baf6af691acd5c50deedbadc119ceba
ToppCell	wk_15-18-Epithelial-Proximal_epithelial-SMG_basal_1\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	KRT6A KRT6B KRT6C FAM83A	2.99e-04	174	82	4	aceca0a22bb1e380835e792681cfc9b752fb5496
ToppCell	Tracheal-10x3prime_v2-Stromal-Pericyte-Muscle_pericyte_systemic\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	HEYL BRSK2 GJC1	3.05e-04	71	82	3	5d63a582229520b2a037f3c27f772e34cdee092b
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m-Epithelial-nan\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT6A KRT6B HCAR2 ESR1	3.05e-04	175	82	4	9a96794df049d8228fea57c1584c160191d36b56
ToppCell	TCGA-Cervix-Primary_Tumor-Cervical_Carcinoma-Non-keratinizing_Cervical_Squamous_Cell_Carcinoma\|TCGA-Cervix / Sample_Type by Project: Shred V9	HCAR3 KRT6A HCAR2 FAM83A	3.12e-04	176	82	4	8513c2a05a34453a16bbcf1c11cb34c580133e47
ToppCell	TCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Squamous_Cell_Carcinoma-5\|TCGA-Lung / Sample_Type by Project: Shred V9	HCAR3 KRT6A KRT6B KRT6C	3.19e-04	177	82	4	a0c7d08469c513cecf87777c19876884f1511570
ToppCell	COVID-19_Severe-MAIT\|COVID-19_Severe / Disease condition and Cell class	MATN2 SYTL2 TIPARP B4GALT1	3.19e-04	177	82	4	8eb69041f482b58325e3539f607923f7b1fa5977
ToppCell	Children_(3_yrs)\|World / Lineage, Cell type, age group and donor	HCAR2 TAOK3 HLA-DPB1 TIPARP	3.26e-04	178	82	4	df2ecd3214590b914f2762db57efe780ba038db3
ToppCell	10x5'v1-week_12-13-Mesenchymal_osteo-stroma-osteochondral_precursor\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	HEYL ENOX1 THSD7B PDZRN3	3.33e-04	179	82	4	98c0c5c8034ae8a4b3ceea7fd1d0386ee5f89d09
ToppCell	human_hepatoblastoma-Tumor_cells-T6\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	ENOX1 AMOT ESR1 SYTL2	3.33e-04	179	82	4	14fc8ccb6b215063d747643f47d780d2b237eb67
ToppCell	critical-Epithelial-Basal\|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	HEYL ASRGL1 RPL35 RPL18	3.40e-04	180	82	4	af6251d550b8a80c104bcbb104478b314a45366e
ToppCell	Children_(3_yrs)-Mesenchymal-pericyte_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	HEYL ENOX1 SYTL2 GJC1	3.47e-04	181	82	4	451b87ac95154bb80018b8dd245b4a6389d81411
ToppCell	RA-07._Pericyte\|RA / Chamber and Cluster_Paper	HEYL SYTL2 GJC1 THSD7B	3.47e-04	181	82	4	8dfb42d096db6c2df9b41303a7199d134d4bff07
ToppCell	RA-07._Pericyte\|World / Chamber and Cluster_Paper	HEYL SYTL2 GJC1 THSD7B	3.54e-04	182	82	4	2075efeae633550fb2eb026d0dfd741c8252482e
ToppCell	LA-07._Pericyte\|World / Chamber and Cluster_Paper	HEYL SYTL2 GJC1 THSD7B	3.62e-04	183	82	4	e3835db4795362b0442d5893baf2a78efcc20428
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	HEYL ENOX1 SYTL2 GJC1	3.62e-04	183	82	4	8a799807fbf24456a9811e0c64068187940a2f71
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	HEYL ENOX1 SYTL2 GJC1	3.69e-04	184	82	4	689a8af81a79a4bb3123cfa01958c953eab5de98
ToppCell	Bac-SEP-Lymphocyte-B-B_naive\|Bac-SEP / Disease, Lineage and Cell Type	HLA-DPB1 SEC62 RPL35 RPL18	3.77e-04	185	82	4	4d9e1eeb353c0b1f82f557856e99c8bf04aa2a7f
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.3\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	KRT6A KRT6B LMO7 FAM83A	3.77e-04	185	82	4	f3fbc3096f85397a959cee17c3c4fcf2d511f3d5
ToppCell	LA-07._Pericyte\|LA / Chamber and Cluster_Paper	HEYL GJC1 THSD7B ITPRID1	3.77e-04	185	82	4	ba5baa4d7f097108622674de5b7f4fd279843d24
ToppCell	droplet-Limb_Muscle-nan-21m-Mesenchymal-skeletal_muscle_satellite_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HEYL SYTL2 RPL35 RPL18	3.85e-04	186	82	4	1cbb1a1c4f0f6078e9c7b4e0dc93d6b6de7e57db
ToppCell	5'-GW_trimst-2-LymphNode-Mesenchymal-Pericytes-angiogenic_pericyte\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HEYL SYTL2 GJC1 THSD7B	3.92e-04	187	82	4	b8f88599e22b9b345c7ec3bbecd87a8b2a033f9f
ToppCell	TCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Ductal_Carcinoma-1\|TCGA-Breast / Sample_Type by Project: Shred V9	KIFBP ESR1 KAT6B RUNDC1	3.92e-04	187	82	4	a716b64ca03d9b61da765bf87f065ac9393303f1
ToppCell	Fetal_29-31_weeks-Mesenchymal-pericyte_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	HEYL SYTL2 GJC1 THSD7B	3.92e-04	187	82	4	fa01a61bfd13feb033ba1e35cf513707b1bff8c8
ToppCell	facs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l20-23\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	HEYL SYTL2 RPL35 RPL18	3.92e-04	187	82	4	69b47f00598d647e2a99427ebddf42c339428e47
ToppCell	5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(nasal)-Club_(nasal)_L.0.2.3.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	KRT6A KRT6B KRT6C RUNDC1	3.92e-04	187	82	4	a6a112689d1c9049f57935ad9d2f4955538427de
ToppCell	wk_08-11-Epithelial-Proximal_epithelial-Proximal_secretory_2\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	KRT6A KRT6B HCAR2 KRT6C	4.00e-04	188	82	4	07705bed928683470a52c8ccfa40ffb9a0971318
ToppCell	facs-MAT-Fat-3m\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA3D MATN2 APLP2 PRPF8	4.00e-04	188	82	4	7da9750255efbc5cf9aed7e3105a337fac63b9f0
ToppCell	Control-Fibroblasts-Adventitial_FB\|Control / group, cell type (main and fine annotations)	SEMA3D EPHA6 ESR1 PDZRN3	4.00e-04	188	82	4	706a26c372add839d947749f0521a0e1f5c9b0ec
ToppCell	COPD-Stromal-SMC\|Stromal / Disease state, Lineage and Cell class	HEYL SYTL2 BRSK2 GJC1	4.00e-04	188	82	4	9ffef4b01d0ddd6913c9ed6be79aeaaabd5e41ed
ToppCell	Fibroblast-C\|World / shred on cell class and cell subclass (v4)	HEYL SEMA3D MATN2 PDZRN3	4.09e-04	189	82	4	58e0400fbab5a0755504275aef5cf7986149abab
ToppCell	facs-Trachea-24m-Epithelial-airway_epithelial-respiratory_basal_cell-basal_epithelial_cell_of_trachea\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	KRT6A HCAR2 LMO7 ITPRID1	4.09e-04	189	82	4	ee15b4fb3a1cfda80bcf210a23f04f242594015e
ToppCell	facs-Trachea-24m-Epithelial-airway_epithelial-respiratory_basal_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	KRT6A HCAR2 LMO7 ITPRID1	4.09e-04	189	82	4	dc6f6fae84347d145bea71b49eaeeb3028e9c4ae
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	HEYL MATN2 SYTL2 PDZRN3	4.09e-04	189	82	4	7ab1cfc1657277858339f7258a0c4ae9cb42fdf8
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_myocytic-mes_pericyte_(14)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	HEYL ENOX1 SYTL2 PDZRN3	4.09e-04	189	82	4	9c2492c38f27e4c699b40680652e4c64911cce52
ToppCell	E16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	HEYL MATN2 GJC1 TIPARP	4.17e-04	190	82	4	106862ef44fcaa0971c3ba0147d13eb08015ca77
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial-intestinal_crypt_stem_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ASRGL1 MCM5 RPL35 AXIN2	4.17e-04	190	82	4	52c59001a079c76249abbaa3141e9e661b83d9a0
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	EPHB2 DCDC1 LMO7 SYTL2	4.17e-04	190	82	4	3fc9e18c7441c0ae8cda65753cc42d0520f4e116
ToppCell	10x_3'_v3-lymph_node_(10x_3'_v3)-lymphocytic-B_lymphocytic-naive_B_cell\|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	HLA-DPB1 SEC62 APLP2 RPL35	4.17e-04	190	82	4	441770ce7b3c81f36f5b15b8e51794f736462457
ToppCell	Fetal_29-31_weeks-Mesenchymal-vascular_smooth_muscle_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	HEYL ENOX1 SYTL2 GJC1	4.17e-04	190	82	4	d6b3a92119b210974a32af3fe9875d60eb02761e
ToppCell	BLOOD--(2)_B_cell-(2)_Naive_B_cells\|(2)_B_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	SEC62 APLP2 RPL35 RPL18	4.17e-04	190	82	4	bde288cea27bbdc3ca05737a00fe30a0103a4c74
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	EPHB2 DCDC1 LMO7 SYTL2	4.25e-04	191	82	4	5a67ff17fb4b9eff641176dff07830c9cd73754e
ToppCell	ICU-NoSEP-Lymphocyte-B-B_naive\|ICU-NoSEP / Disease, Lineage and Cell Type	HLA-DPB1 SEC62 RPL35 RPL18	4.25e-04	191	82	4	f430961a94890fe8755d22e53836be39cb08e153
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	EPHB2 DCDC1 LMO7 SYTL2	4.25e-04	191	82	4	55ab2854a02cdcfc395e49870ccb7290b5e5471d
ToppCell	droplet-Limb_Muscle-nan-3m-Mesenchymal-skeletal_muscle_satellite_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HEYL SYTL2 RPL35 RPL18	4.25e-04	191	82	4	4fcbc214853e115608b3be7b35639247ae41c9dc
ToppCell	droplet-Bladder-Unstain-18m-Epithelial-basal_bladder_epithelial_cell_(Krt5+)\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT6A LMO7 RPL35 RPL18	4.25e-04	191	82	4	49068e3b7d265d4767d7b3c79d455dbc2fd8c6cd
ToppCell	PND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	EPHB2 HEYL SEMA3D MATN2	4.34e-04	192	82	4	ad48c941a3ddfd9a5146bafc2209da577bb50531
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	EPHB2 LMO7 SYTL2 CTNNA1	4.34e-04	192	82	4	f7e7491426bbd6ed29a465b58bf67acb93dbb90a
ToppCell	Severe-B_naive-12\|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)	HLA-DPB1 APLP2 RPL35 RPL18	4.34e-04	192	82	4	c482240645220d1753d76c0aa3a8ca14edb94a75
Computational	Genes in the cancer module 285.	LIN37 CDK2AP2 B4GALT1 RPL18	7.52e-05	49	50	4	MODULE_285
Drug	SC-791	KRT6A KRT6B KRT6C	8.61e-07	6	81	3	CID010291510
Disease	Pachyonychia Congenita, Jadassohn Lewandowsky Type	KRT6A KRT6B	3.81e-05	4	75	2	C1706595
Disease	pachyonychia congenita (is_implicated_in)	KRT6A KRT6B	3.81e-05	4	75	2	DOID:0050449 (is_implicated_in)
Disease	Pachyonychia congenita syndrome	KRT6A KRT6B	3.81e-05	4	75	2	cv:C0265334
Disease	Pachyonychia Congenita, Type 2 (disorder)	KRT6A KRT6B	3.81e-05	4	75	2	C1721007
Disease	Pachyonychia Congenita	KRT6A KRT6B	6.34e-05	5	75	2	C0265334
Disease	velocity of sound measurement	ESR1 WNT16	4.88e-04	13	75	2	EFO_0005654
Disease	Aase Smith syndrome 2	RPL35 RPL18	6.55e-04	15	75	2	C2931850
Disease	hippocampal volume	BRSK2 MCM5 ITPRID1 ATP8B2 AXIN2	9.70e-04	297	75	5	EFO_0005035
Disease	Diamond-Blackfan anemia	RPL35 RPL18	1.06e-03	19	75	2	cv:C1260899
Disease	3-hydroxypropylmercapturic acid measurement	ASRGL1 THSD7B PLA2G4E USP48 CHST3	2.05e-03	352	75	5	EFO_0007014
Disease	obsessive-compulsive disorder	HCAR3 HCAR2 LMO7	2.14e-03	100	75	3	EFO_0004242
Disease	macular degeneration (is_implicated_in)	ESR1 CFI	2.15e-03	27	75	2	DOID:4448 (is_implicated_in)

Protein segments in the cluster

Peptide	Gene	Start	Entry
RMELREHGEKKKRSR	DDX47	411	Q9H0S4
GRCRMIRHSRDKKNE	B4GALT1	336	P15291
KAMRNKLEGEIRRMH	AMOT	491	Q4VCS5
SCGVKNRMHIRRKRI	CFI	326	P05156
NRMHIRRKRIVGGKR	CFI	331	P05156
SKDRKERVHQGMVRA	ASRGL1	16	Q7L266
MLRRLDKIRFRGHKR	GRAMD4	1	Q6IC98
GVGIFMHRRSKKVQR	HLA-DPB1	241	P04440
RVGSKKQLQREMHRS	AXIN2	326	Q9Y2T1
KKQKAQHRCMRRVGR	ATP8B2	1126	P98198
HLVKAKEQRRRREFM	PDZRN3	981	Q9UPQ7
RKMFGRDRIINERHL	TIPARP	516	Q7Z3E1
HMIDKRDGRFVIIRR	KAT6B	946	Q8WYB5
QLEIRHRNRMDRVKK	APLP2	396	Q06481
TMRHKMRQLKGRRVA	DCDC1	1576	M0R2J8
KNKGRDVETMRRHRN	KPNA3	16	O00505
RMIQRLRSEIDHVKK	KRT6C	386	P48668
HQRRKKRREMDDGLA	LIN37	71	Q96GY3
RKSEVERAVKRMRHL	MATN2	116	O00339
LRRGEIQHRMQRKVL	MCM5	716	P33992
AKEHRRRMGKLLRRA	ITPRID1	246	Q6ZRS4
RMIQRLRSEIDHVKK	KRT6A	386	P02538
RQRQMDRHAKIKRAI	HCAR2	216	Q8TDS4
NRHGKRRPERKSMEV	BRSK2	371	Q8IWQ3
KFIRRRGAHRIHVEM	EPHB2	76	P29323
FERHTKGIGRKVMER	GPATCH3	406	Q96I76
RKDRRGGRMLKHKRQ	ESR1	256	P03372
RMIQRLRSEIDHVKK	KRT6B	386	P04259
IHGAIVRMLLEKRRR	OR51J1	301	Q9H342
VKMRNDRELRGRLHA	LSM3	31	P62310
KGRKRMHLELREGLT	DDHD2	566	O94830
REASRLRHKKRLMVE	LMO7	676	Q8WWI1
MQARKKHRGIIEKRR	HEYL	41	Q9NQ87
MSRSRHLGKIRKRLE	FAM83A	1	Q86UY5
HAARKKRQMARELGD	PAXBP1	226	Q9Y5B6
MHRKKVDNRIRILIE	NAT10	1	Q9H0A0
VRHRDTRQRFAMKKI	MAST1	391	Q9Y2H9
EVHAQSRRRRKREKM	PLA2G4E	211	Q3MJ16
KSAMERLKRGIIHAR	CDK2AP2	96	O75956
RRSMRKHAEKERLRE	EPB41L5	11	Q9HCM4
EMEGISHKRRVRRKT	HEATR3	326	Q7Z4Q2
MSKKGRPQRQRREVH	GABRR1	36	P24046
RDLRRQLRKAVMDHV	CTNNA1	376	P35221
ERVRGRAKLRIEKAM	CDC37	261	Q16543
KHDGRRRIREDGLMK	GJC1	161	P36383
GDERKARMHERIAKQ	CC2D1B	406	Q5T0F9
HHRMRRKAAVKRLDP	C2orf81	331	A6NN90
RIHKDEIMRNRKRVK	DRC3	486	Q9H069
LIQKHRRRQRKMGED	CAPN2	411	P17655
GKQAHVELAERMRKR	POLD1	896	P28340
KQRMRAREERHRRKL	ENOX1	231	Q8TC92
ERRCKMHKRRIAMLE	KIFBP	441	Q96EK5
GSRHRRMEAVRLRKE	NKAP	356	Q8N5F7
AIKTLKGGHMDRQRR	EPHA6	661	Q9UF33
VRMKRRVGVKSAPRH	HSFX1	206	Q9UBD0
VKKVRETGLHLMRRA	RUNDC1	331	Q96C34
IHGADIIRASMRKKR	SYTL2	66	Q9HCH5
KKTRAMRRRLNKHEE	RPL35	86	P42766
HKSRMGVAERQQKLR	SMYD4	576	Q8IYR2
TDEVKVGKRMVRGRH	SEPTIN14	251	Q6ZU15
REEIRRVRNKFVMMH	TCEAL8	86	Q8IYN2
HMREAVRRLKSKGQI	TAF11	186	Q15544
RQRQMDRHAKIKRAI	HCAR3	216	P49019
EKQDREIFHRTMRKR	SLC9A3	646	P48764
GMSRGKVIRLHRRKQ	SETD5	111	Q9C0A6
KRRERELHRKHVMEL	TAOK3	691	Q9H2K8
MKKKRNRRHHRDLDE	SEMA3D	756	O95025
RKEHMALKAVRIRQL	CHST3	266	Q7LGC8
VRKIIRDHGDMTNRK	PRPF8	66	Q6P2Q9
MGVDIRHNKDRKVRR	RPL18	1	Q07020
MAERRRHKKRIQEVG	SEC62	1	Q99442
RRKREEFIQKHGRGM	SRPRA	211	P08240
KMRRREKDQRKIPIH	WNT16	266	Q9UBV4
KNQGRKLRSHMVERL	ZNF709	56	Q8N972
RMKSDHKRETERVVR	ZMYND11	481	Q15326
KRQMERIRAKQEKHR	PIEZO1	1351	Q92508
GKKGFRTRQRHVLME	THSD7B	506	Q9C0I4
DARREVHIKRMEERK	ARHGAP21	776	Q5T5U3
VIRRSMRHRKVRGEK	USP48	931	Q86UV5
MRHRKVRGEKALLVS	USP48	936	Q86UV5
DLVSRRKHMRIHIVK	ZNF317	401	Q96PQ6
AGRAMHLLKKRERQR	FAM50B	11	Q9Y247
IHGVSREKIHRMKER	N4BP2L1	161	Q5TBK1
IKRVHKFMEREGRRP	MMUT	601	P22033