Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	cell adhesion molecule binding	CDH23 PFKP PTPRT CNTN6 MPRIP FASN EEF2 PTPN11 PTPRD PTPRF PKP3 DCHS1 SCRIB TNXB	1.40e-04	599	147	14	GO:0050839
GeneOntologyMolecularFunction	methenyltetrahydrofolate cyclohydrolase activity	MTHFD2 MTHFD2L	1.61e-04	3	147	2	GO:0004477
GeneOntologyMolecularFunction	methylenetetrahydrofolate dehydrogenase (NAD+) activity	MTHFD2 MTHFD2L	1.61e-04	3	147	2	GO:0004487
GeneOntologyMolecularFunction	cadherin binding	CDH23 PFKP PTPRT MPRIP FASN EEF2 PTPN11 PKP3 DCHS1 SCRIB	2.12e-04	339	147	10	GO:0045296
GeneOntologyMolecularFunction	transmembrane receptor protein tyrosine phosphatase activity	PTPRT PTPRD PTPRF	2.46e-04	17	147	3	GO:0005001
GeneOntologyMolecularFunction	transmembrane receptor protein phosphatase activity	PTPRT PTPRD PTPRF	2.46e-04	17	147	3	GO:0019198
GeneOntologyMolecularFunction	methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity	MTHFD2 MTHFD2L	3.20e-04	4	147	2	GO:0004486
GeneOntologyMolecularFunction	methylenetetrahydrofolate dehydrogenase (NADP+) activity	MTHFD2 MTHFD2L	3.20e-04	4	147	2	GO:0004488
GeneOntologyMolecularFunction	cyclohydrolase activity	MTHFD2 MTHFD2L	5.31e-04	5	147	2	GO:0019238
GeneOntologyMolecularFunction	signaling receptor complex adaptor activity	SORBS1 CRK PTPN11 G3BP2	6.70e-04	54	147	4	GO:0030159
GeneOntologyMolecularFunction	alkaline phosphatase activity	CILP ALPI	7.92e-04	6	147	2	GO:0004035
GeneOntologyMolecularFunction	protein tyrosine phosphatase activity	PTPRT PTPN11 PTPRD PTPRF PTPRS	9.91e-04	103	147	5	GO:0004725
GeneOntologyMolecularFunction	calcium ion binding	FLG FKBP10 NAALADL1 SYT12 PCDHGA3 CDH23 FLG2 RYR2 CELSR1 CADPS TCHHL1 DCHS1 PRRG3 PCDHGA8	1.29e-03	749	147	14	GO:0005509
GeneOntologyMolecularFunction	exopeptidase activity	TPP2 NAALADL1 NPEPL1 MINDY2 FOLH1B	1.33e-03	110	147	5	GO:0008238
GeneOntologyMolecularFunction	insulin receptor binding	SORBS1 PTPN11 PTPRF	1.37e-03	30	147	3	GO:0005158
GeneOntologyBiologicalProcess	cell-cell adhesion via plasma-membrane adhesion molecules	PCDHGA3 CDH23 WNK1 PTPRT CNTN6 CELSR1 PTPRD PTPRF PTPRS DCHS1 PCDHGA8	1.37e-05	313	145	11	GO:0098742
GeneOntologyCellularComponent	neuron to neuron synapse	TANC2 SYT12 RUSC1 MPDZ GRIA1 CAMK1 PTPRT SLC6A9 PTPRD PTPRF PTPRS ARC SCRIB KCNT1	2.01e-05	523	147	14	GO:0098984
GeneOntologyCellularComponent	postsynaptic density	TANC2 RUSC1 MPDZ GRIA1 CAMK1 PTPRT SLC6A9 PTPRF PTPRS ARC SCRIB KCNT1	8.52e-05	451	147	12	GO:0014069
GeneOntologyCellularComponent	excitatory synapse	GRIA1 CNTN6 SLC6A9 RAB3GAP1 PTPRF CADPS2	1.10e-04	107	147	6	GO:0060076
GeneOntologyCellularComponent	postsynaptic density membrane	GRIA1 PTPRT PTPRF PTPRS ARC SCRIB KCNT1	1.25e-04	157	147	7	GO:0098839
GeneOntologyCellularComponent	asymmetric synapse	TANC2 RUSC1 MPDZ GRIA1 CAMK1 PTPRT SLC6A9 PTPRF PTPRS ARC SCRIB KCNT1	1.44e-04	477	147	12	GO:0032279
GeneOntologyCellularComponent	postsynaptic specialization	TANC2 RUSC1 MPDZ GRIA1 CAMK1 PTPRT SLC6A9 PTPRF PTPRS ARC SCRIB KCNT1	2.35e-04	503	147	12	GO:0099572
GeneOntologyCellularComponent	keratohyalin granule	FLG FLG2	4.84e-04	5	147	2	GO:0036457
GeneOntologyCellularComponent	postsynaptic specialization membrane	GRIA1 PTPRT PTPRF PTPRS ARC SCRIB KCNT1	5.61e-04	201	147	7	GO:0099634
GeneOntologyCellularComponent	postsynaptic membrane	GRIA1 NBEA PTPRT SLC6A9 PTPRF PTPRS ARC SCRIB CADPS2 KCNT1	6.01e-04	405	147	10	GO:0045211
GeneOntologyCellularComponent	synaptic membrane	GRIA1 NBEA PTPRT CNTN6 SLC6A9 PTPRD PTPRF PTPRS ARC SCRIB CADPS2 KCNT1	8.71e-04	583	147	12	GO:0097060
GeneOntologyCellularComponent	contractile actin filament bundle	XIRP1 PPP1R12B SORBS1 MPRIP PTPN11	9.60e-04	107	147	5	GO:0097517
GeneOntologyCellularComponent	stress fiber	XIRP1 PPP1R12B SORBS1 MPRIP PTPN11	9.60e-04	107	147	5	GO:0001725
GeneOntologyCellularComponent	desmosome	CDSN XIRP1 PKP3	9.81e-04	28	147	3	GO:0030057
GeneOntologyCellularComponent	cornified envelope	FLG CDSN FLG2 PKP3	1.42e-03	69	147	4	GO:0001533
GeneOntologyCellularComponent	actomyosin	XIRP1 PPP1R12B SORBS1 MPRIP PTPN11	1.43e-03	117	147	5	GO:0042641
GeneOntologyCellularComponent	actin filament bundle	XIRP1 PPP1R12B SORBS1 MPRIP PTPN11	1.49e-03	118	147	5	GO:0032432
GeneOntologyCellularComponent	glutamatergic synapse	TANC2 CNTNAP1 MPDZ GRIA1 NBEA CAMK1 PTPRT EEF2 PTPRD CADPS PTPRS ARC SCRIB CADPS2	1.90e-03	817	147	14	GO:0098978
Domain	PTPc	PTPRT PTPN11 PTPRD PTPRF PTPRS	8.74e-06	36	147	5	SM00194
Domain	TYR_PHOSPHATASE_PTP	PTPRT PTPN11 PTPRD PTPRF PTPRS	1.31e-05	39	147	5	PS50055
Domain	PTPase_domain	PTPRT PTPN11 PTPRD PTPRF PTPRS	1.68e-05	41	147	5	IPR000242
Domain	Y_phosphatase	PTPRT PTPN11 PTPRD PTPRF PTPRS	1.68e-05	41	147	5	PF00102
Domain	CAPS	CADPS CADPS2	6.15e-05	2	147	2	IPR033227
Domain	Filaggrin	FLG FLG2	6.15e-05	2	147	2	IPR003303
Domain	PTPc_motif	PTPRT PTPN11 PTPRD PTPRF PTPRS	1.00e-04	59	147	5	SM00404
Domain	Tyr_Pase_cat	PTPRT PTPN11 PTPRD PTPRF PTPRS	1.00e-04	59	147	5	IPR003595
Domain	THF_DHG_CYH_1	MTHFD2 MTHFD2L	1.84e-04	3	147	2	PS00766
Domain	THF_DHG_CYH_2	MTHFD2 MTHFD2L	1.84e-04	3	147	2	PS00767
Domain	THF_DH/CycHdrlase_CS	MTHFD2 MTHFD2L	1.84e-04	3	147	2	IPR020867
Domain	Tyr_Pase_AS	PTPRT PTPN11 PTPRD PTPRF PTPRS	2.76e-04	73	147	5	IPR016130
Domain	THF_DHG_CYH_C	MTHFD2 MTHFD2L	3.65e-04	4	147	2	PF02882
Domain	THF_DH/CycHdrlase_cat_dom	MTHFD2 MTHFD2L	3.65e-04	4	147	2	IPR020630
Domain	THF_DH/CycHdrlase_NAD-bd_dom	MTHFD2 MTHFD2L	3.65e-04	4	147	2	IPR020631
Domain	THF_DHG_CYH	MTHFD2 MTHFD2L	3.65e-04	4	147	2	PF00763
Domain	THF_DH/CycHdrlase	MTHFD2 MTHFD2L	3.65e-04	4	147	2	IPR000672
Domain	TYR_PHOSPHATASE_1	PTPRT PTPN11 PTPRD PTPRF PTPRS	5.89e-04	86	147	5	PS00383
Domain	DUF1041	CADPS CADPS2	6.06e-04	5	147	2	SM01145
Domain	TYR_PHOSPHATASE_dom	PTPRT PTPN11 PTPRD PTPRF PTPRS	6.21e-04	87	147	5	IPR000387
Domain	TYR_PHOSPHATASE_2	PTPRT PTPN11 PTPRD PTPRF PTPRS	6.21e-04	87	147	5	PS50056
Domain	Ig_I-set	CILP IGFBPL1 CNTN6 PTPRD PTPRF LRIG1 PTPRS	7.76e-04	190	147	7	IPR013098
Domain	I-set	CILP IGFBPL1 CNTN6 PTPRD PTPRF LRIG1 PTPRS	7.76e-04	190	147	7	PF07679
Domain	-	PTPRT PTPN11 PTPRD PTPRF PTPRS	8.01e-04	92	147	5	3.90.190.10
Domain	TFR_dimer	NAALADL1 FOLH1B	9.04e-04	6	147	2	PF04253
Domain	-	NAALADL1 FOLH1B	9.04e-04	6	147	2	1.20.930.40
Domain	Prot-tyrosine_phosphatase-like	PTPRT PTPN11 PTPRD PTPRF PTPRS	1.11e-03	99	147	5	IPR029021
Domain	S100_CABP	FLG FLG2 TCHHL1	1.22e-03	27	147	3	PS00303
Domain	S_100	FLG FLG2 TCHHL1	1.22e-03	27	147	3	PF01023
Domain	Munc13_1	CADPS CADPS2	1.26e-03	7	147	2	IPR014770
Domain	MHD1	CADPS CADPS2	1.26e-03	7	147	2	PS51258
Domain	TFR-like_dimer_dom	NAALADL1 FOLH1B	1.26e-03	7	147	2	IPR007365
Domain	DUF1041	CADPS CADPS2	1.26e-03	7	147	2	PF06292
Domain	CAPS_dom	CADPS CADPS2	1.26e-03	7	147	2	IPR010439
Domain	S100_Ca-bd_sub	FLG FLG2 TCHHL1	1.35e-03	28	147	3	IPR013787
Domain	S_100	FLG FLG2 TCHHL1	1.35e-03	28	147	3	SM01394
Domain	FBG	CNTNAP1 CNTNAP3 TNXB	1.50e-03	29	147	3	SM00186
Domain	-	CNTNAP1 CNTNAP3 TNXB	1.66e-03	30	147	3	3.90.215.10
Domain	Fibrinogen_a/b/g_C_1	CNTNAP1 CNTNAP3 TNXB	1.66e-03	30	147	3	IPR014716
Domain	Cadherin_CS	PCDHGA3 CDH23 CELSR1 DCHS1 PCDHGA8	1.71e-03	109	147	5	IPR020894
Domain	ConA-like_dom	CNTNAP1 CNTNAP3 NBEA HNRNPUL1 PTPRT RYR2 CELSR1	1.76e-03	219	147	7	IPR013320
Domain	fn3	PTPRT CNTN6 PTPRD PTPRF PTPRS TNXB	1.79e-03	162	147	6	PF00041
Domain	CADHERIN_1	PCDHGA3 CDH23 CELSR1 DCHS1 PCDHGA8	2.00e-03	113	147	5	PS00232
Domain	Cadherin	PCDHGA3 CDH23 CELSR1 DCHS1 PCDHGA8	2.00e-03	113	147	5	PF00028
Domain	FIBRINOGEN_C_1	CNTNAP1 CNTNAP3 TNXB	2.00e-03	32	147	3	PS00514
Domain	Fibrinogen_a/b/g_C_dom	CNTNAP1 CNTNAP3 TNXB	2.00e-03	32	147	3	IPR002181
Domain	FIBRINOGEN_C_2	CNTNAP1 CNTNAP3 TNXB	2.00e-03	32	147	3	PS51406
Domain	CADHERIN_2	PCDHGA3 CDH23 CELSR1 DCHS1 PCDHGA8	2.08e-03	114	147	5	PS50268
Domain	-	PCDHGA3 CDH23 CELSR1 DCHS1 PCDHGA8	2.08e-03	114	147	5	2.60.40.60
Domain	CA	PCDHGA3 CDH23 CELSR1 DCHS1 PCDHGA8	2.16e-03	115	147	5	SM00112
Domain	Cadherin-like	PCDHGA3 CDH23 CELSR1 DCHS1 PCDHGA8	2.25e-03	116	147	5	IPR015919
Domain	Cadherin	PCDHGA3 CDH23 CELSR1 DCHS1 PCDHGA8	2.42e-03	118	147	5	IPR002126
Domain	IGc2	CILP IGFBPL1 CNTN6 PTPRD PTPRF LRIG1 PTPRS	2.62e-03	235	147	7	SM00408
Domain	Ig_sub2	CILP IGFBPL1 CNTN6 PTPRD PTPRF LRIG1 PTPRS	2.62e-03	235	147	7	IPR003598
Pathway	REACTOME_SYNAPTIC_ADHESION_LIKE_MOLECULES	GRIA1 PTPRD PTPRF PTPRS	9.00e-06	20	96	4	MM15485
Pathway	REACTOME_SYNAPTIC_ADHESION_LIKE_MOLECULES	GRIA1 PTPRD PTPRF PTPRS	1.11e-05	21	96	4	M27736
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	TANC2 TPP2 NHSL2 CNTNAP1 MPDZ GRIA1 NBEA SORBS1 ARMCX4 SMC2 MPRIP EEF2 PTPRD AGO3 PTPRS G3BP2 SYNE2 ZNF516 DCHS1 ARC SCRIB PARD3 KCNT1	3.99e-11	963	152	23	28671696
Pubmed	LAR receptor phospho-tyrosine phosphatases regulate NMDA-receptor responses.	PTPRD PTPRF PTPRS	8.18e-08	3	152	3	31985401
Pubmed	Trans-synaptic adhesions between netrin-G ligand-3 (NGL-3) and receptor tyrosine phosphatases LAR, protein-tyrosine phosphatase delta (PTPdelta), and PTPsigma via specific domains regulate excitatory synapse formation.	PTPRD PTPRF PTPRS	8.18e-08	3	152	3	20139422
Pubmed	Intact synapse structure and function after combined knockout of PTPδ, PTPσ, and LAR.	PTPRD PTPRF PTPRS	8.18e-08	3	152	3	33656439
Pubmed	Developmental expression of the cell adhesion molecule-like protein tyrosine phosphatases LAR, RPTPdelta and RPTPsigma in the mouse.	PTPRD PTPRF PTPRS	8.18e-08	3	152	3	9784606
Pubmed	Dynamic changes in the expression of protein tyrosine phosphatases during preimplantation mouse development: semi-quantification by real-time PCR.	PTPN11 PTPRF PTPRS	3.26e-07	4	152	3	14967925
Pubmed	The LAR/PTP delta/PTP sigma subfamily of transmembrane protein-tyrosine-phosphatases: multiple human LAR, PTP delta, and PTP sigma isoforms are expressed in a tissue-specific manner and associate with the LAR-interacting protein LIP.1.	PTPRD PTPRF PTPRS	3.26e-07	4	152	3	8524829
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	TANC2 KIF26A PIEZO1 NLRX1 LMTK2 ATG2A PTCH1 WNK1 FAM83H MPRIP PCNX2 FASN CELSR1 TNRC18 PTPRF PTPRS ZNF516 ARC RIPOR1	3.98e-07	1105	152	19	35748872
Pubmed	Protein tyrosine phosphatases expression during development of mouse superior colliculus.	PTPN11 PTPRD PTPRF PTPRS	7.98e-07	17	152	4	19727691
Pubmed	Multiple interactions between receptor protein-tyrosine phosphatase (RPTP) alpha and membrane-distal protein-tyrosine phosphatase domains of various RPTPs.	PTPRD PTPRF PTPRS	8.13e-07	5	152	3	10777529
Pubmed	Interleukin-1 receptor accessory protein organizes neuronal synaptogenesis as a cell adhesion molecule.	PTPRD PTPRF PTPRS	8.13e-07	5	152	3	22357843
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	TANC2 TPP2 DENND2A PPP1R12B CNTNAP1 ACOT7 GRIA1 NBEA SORBS1 MAP7 PFKP SUCLA2 MPRIP FASN EEF2 LRIG1 CADPS PTPRS G3BP2 KNDC1 SCRIB	1.21e-06	1431	152	21	37142655
Pubmed	Comparative interactome analysis of α-arrestin families in human and Drosophila.	CAND2 PMPCB LMTK2 SMC2 PTPRF WDR11 PTPRS WDR6 SCRIB PARD3	1.31e-06	313	152	10	38270169
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	FLG FAM184B FAM114A1 PMPCB NHSL2 PCDHGA3 PPP1R12B GRIA1 ZBTB41 PFKP SMC2 MINDY2 RYR2 RFTN1 FASN EEF2 TNRC18 TCHHL1 SYNE2 CADPS2 PCDHGA8	1.37e-06	1442	152	21	35575683
Pubmed	Maturation of ureter-bladder connection in mice is controlled by LAR family receptor protein tyrosine phosphatases.	PTPRD PTPRF PTPRS	1.62e-06	6	152	3	19273906
Pubmed	Intra- and intermolecular interactions between intracellular domains of receptor protein-tyrosine phosphatases.	PTPRD PTPRF PTPRS	2.83e-06	7	152	3	12376545
Pubmed	Modulation of apoptotic response by LAR family phosphatases-cIAP1 signaling during urinary tract morphogenesis.	PTPRD PTPRF PTPRS	2.83e-06	7	152	3	29073098
Pubmed	mTORC1 activity regulates post-translational modifications of glycine decarboxylase to modulate glycine metabolism and tumorigenesis.	MPDZ HNRNPUL1 MAP7 MPRIP FASN EEF2 AGO3 G3BP2 SCRIB	3.60e-06	274	152	9	34244482
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	TPP2 PMPCB LEMD3 PPP1R12B LMTK2 NBEA SIX4 C2CD4C PTPRT RFTN1 PTPN11 PTPRD PTPRF WDR11 PTPRS SYNE2 SCRIB	3.75e-06	1049	152	17	27880917
Pubmed	Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.	DDX59 LEMD3 LMTK2 HNRNPUL1 MPRIP GTF2H4 WDR6 G3BP2 TBC1D12 SCRIB SLX4	4.11e-06	440	152	11	34244565
Pubmed	Combinatorial expression of neurexins and LAR-type phosphotyrosine phosphatase receptors instructs assembly of a cerebellar circuit.	PTPRD PTPRF PTPRS	4.51e-06	8	152	3	37591863
Pubmed	Protein Tyrosine Phosphatase δ Mediates the Sema3A-Induced Cortical Basal Dendritic Arborization through the Activation of Fyn Tyrosine Kinase.	PTPRD PTPRF PTPRS	4.51e-06	8	152	3	28637841
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	TANC2 USP22 LMTK2 MPDZ SORBS1 HNRNPUL1 MAP7 PFKP WNK1 FAM83H MPRIP SYNE2 PLEKHA2 SCRIB PARD3	6.15e-06	861	152	15	36931259
Pubmed	A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.	FKBP10 CAND2 PMPCB LEMD3 ACOT7 MPDZ SIX4 PFKP SMC2 FASN PTPN11 PTPRD PTPRF PTPRS WDR6 PKP3	6.22e-06	974	152	16	28675297
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	FKBP10 FAM184B CAND2 PMPCB LEMD3 PIEZO1 MPDZ HNRNPUL1 MAP7 PFKP SUCLA2 ARMC1 MPRIP RAB3GAP1 COCH WDR11 WDR6 SYNE2 SCRIB PARD3	8.15e-06	1487	152	20	33957083
Pubmed	High-throughput analyses of hnRNP H1 dissects its multi-functional aspect.	FKBP10 SYT12 INHBB WNK1 RFTN1 CLIP3 EEF2 RAB3GAP1 PTPN11 PTPRD WDR6 G3BP2 PLEKHA2 HEMK1 LRP5L RNASEH1	1.12e-05	1021	152	16	26760575
Pubmed	PTPσ functions as a presynaptic receptor for the glypican-4/LRRTM4 complex and is essential for excitatory synaptic transmission.	PTPRD PTPRF PTPRS	1.32e-05	11	152	3	25624497
Pubmed	A novel receptor-type protein tyrosine phosphatase with a single catalytic domain is specifically expressed in mouse brain.	PTPRD PTPRF PTPRS	1.32e-05	11	152	3	7832766
Pubmed	Liprins, a family of LAR transmembrane protein-tyrosine phosphatase-interacting proteins.	PTPRD PTPRF PTPRS	1.75e-05	12	152	3	9624153
Pubmed	CAPS1 and CAPS2 regulate stability and recruitment of insulin granules in mouse pancreatic beta cells.	CADPS CADPS2	1.90e-05	2	152	2	18177725
Pubmed	Analysis of multigene families by DNA fingerprinting of conserved domains: directed cloning of tissue-specific protein tyrosine phosphatases.	PTPN11 PTPRS	1.90e-05	2	152	2	8479755
Pubmed	Src homology 2 domain-containing phosphotyrosine phosphatase 2 (Shp2) controls surface GluA1 protein in synaptic homeostasis.	GRIA1 PTPN11	1.90e-05	2	152	2	28768764
Pubmed	Derepression of the USP22-FASN axis by p53 loss under oxidative stress drives lipogenesis and tumorigenesis.	USP22 FASN	1.90e-05	2	152	2	36333288
Pubmed	CAPS-1 and CAPS-2 are essential synaptic vesicle priming proteins.	CADPS CADPS2	1.90e-05	2	152	2	18022372
Pubmed	Perturbed expression pattern of the immediate early gene Arc in the dentate gyrus of GluA1 C-terminal palmitoylation-deficient mice.	GRIA1 ARC	1.90e-05	2	152	2	30536651
Pubmed	The mouse gene Ptprf encoding the leukocyte common antigen-related molecule LAR: cloning, characterization, and chromosomal localization.	PTPRD PTPRF	1.90e-05	2	152	2	7665159
Pubmed	CAPS-1 requires its C2, PH, MHD1 and DCV domains for dense core vesicle exocytosis in mammalian CNS neurons.	CADPS CADPS2	1.90e-05	2	152	2	28883501
Pubmed	Uncommon variants in FLG2 and TCHHL1 are associated with remission of atopic dermatitis in a large longitudinal US cohort.	FLG2 TCHHL1	1.90e-05	2	152	2	34984527
Pubmed	Plakophilin 3 and Par3 facilitate desmosomes' association with the apical junctional complex.	PKP3 PARD3	1.90e-05	2	152	2	34260281
Pubmed	Two distinct secretory vesicle-priming steps in adrenal chromaffin cells.	CADPS CADPS2	1.90e-05	2	152	2	20855507
Pubmed	Global proteomic assessment of the classical protein-tyrosine phosphatome and "Redoxome".	PTPN11 PTPRD	1.90e-05	2	152	2	21884940
Pubmed	CAPS facilitates filling of the rapidly releasable pool of large dense-core vesicles.	CADPS CADPS2	1.90e-05	2	152	2	18495893
Pubmed	Mutations in the planar cell polarity genes CELSR1 and SCRIB are associated with the severe neural tube defect craniorachischisis.	CELSR1 SCRIB	1.90e-05	2	152	2	22095531
Pubmed	The armadillo family of structural proteins.	ARMCX4 ARMC1	1.90e-05	2	152	2	9770300
Pubmed	The second catalytic domain of protein tyrosine phosphatase delta (PTP delta) binds to and inhibits the first catalytic domain of PTP sigma.	PTPRD PTPRS	1.90e-05	2	152	2	9566880
Pubmed	CAPS-1 promotes fusion competence of stationary dense-core vesicles in presynaptic terminals of mammalian neurons.	CADPS CADPS2	1.90e-05	2	152	2	25719439
Pubmed	Post-transcriptional inhibition of luciferase reporter assays by the Nod-like receptor proteins NLRX1 and NLRC3.	NLRX1 NLRC3	1.90e-05	2	152	2	22718770
Pubmed	Expression of filaggrin-2 protein in the epidermis of human skin diseases: a comparative analysis with filaggrin.	FLG FLG2	1.90e-05	2	152	2	24813994
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	DENND2A BRPF3 CAND2 KIF26A PIEZO1 PHRF1 LMTK2 ATG2A NPEPL1 ZNF516 KCNT1	2.29e-05	529	152	11	14621295
Pubmed	Mutant p53 interactome identifies nardilysin as a p53R273H-specific binding partner that promotes invasion.	MPDZ HNRNPUL1 PARD3	2.88e-05	14	152	3	22653443
Pubmed	Pals1 is a major regulator of the epithelial-like polarization and the extension of the myelin sheath in peripheral nerves.	MPDZ SCRIB PARD3	3.58e-05	15	152	3	20237282
Pubmed	Inactivation of LAR family phosphatase genes Ptprs and Ptprf causes craniofacial malformations resembling Pierre-Robin sequence.	PTCH1 PTPRF PTPRS	3.58e-05	15	152	3	23863482
Pubmed	Distinct Roles for Rac1 in Sertoli Cell Function during Testicular Development and Spermatogenesis.	INHBB CDH23 SCRIB PARD3	3.79e-05	43	152	4	32294451
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	PMPCB HNRNPUL1 MAP7 PFKP FLG2 SMC2 FAM83H MPRIP FASN EEF2 GTF2H4 WDR11 WDR6 PKP3 G3BP2 SCRIB GAPDHS	3.82e-05	1257	152	17	36526897
Pubmed	E-cadherin interactome complexity and robustness resolved by quantitative proteomics.	SORBS1 PFKP CRK FAM83H MPRIP FASN EEF2 PKP3 PLEKHA2 SCRIB PARD3	4.16e-05	565	152	11	25468996
Pubmed	Conserved molecular signatures of neurogenesis in the hippocampal subgranular zone of rodents and primates.	IGFBPL1 PTPRT FASN MOXD1 PTPRD CADPS WDR6 DCHS1 CADPS2	4.42e-05	376	152	9	24154525
Pubmed	Hedgehog-Activated Fat4 and PCP Pathways Mediate Mesenchymal Cell Clustering and Villus Formation in Gut Development.	NKX3-2 PTCH1 DCHS1	5.32e-05	17	152	3	32155439
Pubmed	Evidence that the tandem-pleckstrin-homology-domain-containing protein TAPP1 interacts with Ptd(3,4)P2 and the multi-PDZ-domain-containing protein MUPP1 in vivo.	MPDZ PLEKHA2	5.68e-05	3	152	2	11802782
Pubmed	Shp2 promotes metastasis of prostate cancer by attenuating the PAR3/PAR6/aPKC polarity protein complex and enhancing epithelial-to-mesenchymal transition.	PTPN11 PARD3	5.68e-05	3	152	2	26050620
Pubmed	GATA3 regulates FLG and FLG2 expression in human primary keratinocytes.	FLG FLG2	5.68e-05	3	152	2	28928464
Pubmed	Identification of three novel non-classical cadherin genes through comprehensive analysis of large cDNAs.	CDH23 DCHS1	5.68e-05	3	152	2	11597768
Pubmed	Pathogenic variants of DYNC2H1, KIAA0556, and PTPN11 associated with hypothalamic hamartoma.	PTPN11 KATNIP	5.68e-05	3	152	2	31197031
Pubmed	Beyond the inflammasome: regulatory NOD-like receptor modulation of the host immune response following virus exposure.	NLRX1 NLRC3	5.68e-05	3	152	2	26763980
Pubmed	Secretory vesicle priming by CAPS is independent of its SNARE-binding MUN domain.	CADPS CADPS2	5.68e-05	3	152	2	25437547
Pubmed	Filaggrin and filaggrin 2 processing are linked together through skin aspartic acid protease activation.	FLG FLG2	5.68e-05	3	152	2	32437351
Pubmed	Cloning and characterization of human CADPS and CADPS2, new members of the Ca2+-dependent activator for secretion protein family.	CADPS CADPS2	5.68e-05	3	152	2	12659812
Pubmed	An Alternative Exon of CAPS2 Influences Catecholamine Loading into LDCVs of Chromaffin Cells.	CADPS CADPS2	5.68e-05	3	152	2	30389842
Pubmed	Chondroitin Sulfate Proteoglycans Negatively Modulate Spinal Cord Neural Precursor Cells by Signaling Through LAR and RPTPσ and Modulation of the Rho/ROCK Pathway.	PTPRD PTPRF	5.68e-05	3	152	2	25703008
Pubmed	Ca2+-dependent activator proteins of secretion promote vesicular monoamine uptake.	CADPS CADPS2	5.68e-05	3	152	2	19008227
Pubmed	Whole-genome methylation profiling of the retinal pigment epithelium of individuals with age-related macular degeneration reveals differential methylation of the SKI, GTF2H4, and TNXB genes.	GTF2H4 TNXB	5.68e-05	3	152	2	30642396
Pubmed	Structural basis for LAR-RPTP/Slitrk complex-mediated synaptic adhesion.	PTPRD PTPRS	5.68e-05	3	152	2	25394468
Pubmed	Defects of filaggrin-like proteins in both lesional and nonlesional atopic skin.	FLG FLG2	5.68e-05	3	152	2	23403047
Pubmed	FAM83H and SCRIB stabilize β-catenin and stimulate progression of gastric carcinoma.	FAM83H SCRIB	5.68e-05	3	152	2	32564009
Pubmed	Morphology, GluR1 and GRIP-C localization differ in octopus cells of C57BL6 and B6Cast mice.	CDH23 GRIA1	5.68e-05	3	152	2	12204345
Pubmed	A family of Ca2+-dependent activator proteins for secretion: comparative analysis of structure, expression, localization, and function.	CADPS CADPS2	5.68e-05	3	152	2	14530279
Pubmed	Protein-tyrosine phosphatase expression in pre-B cell NALM-6.	PTPN11 PTPRS	5.68e-05	3	152	2	1370651
Pubmed	Role of the polarity protein Scribble for podocyte differentiation and maintenance.	SCRIB PARD3	5.68e-05	3	152	2	22586490
Pubmed	Identification of new ciliary signaling pathways in the brain and insights into neurological disorders.	CNTNAP1 MPDZ C2CD4C ADCY3 MSRA SLC6A9 DENND4B RIPOR1 CADPS2	7.82e-05	405	152	9	38187761
Pubmed	Ubiquitin-assisted phase separation of dishevelled-2 promotes Wnt signalling.	LEMD3 PFKP SMC2 EEF2 PKP3 PARD3	7.96e-05	161	152	6	36398662
Pubmed	Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion.	PTPRT CNTN6 PTPRD PTPRF LRIG1 PTPRS	8.24e-05	162	152	6	25826454
Pubmed	Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	TANC2 PHRF1 NBEA AGO3 CADPS2	8.44e-05	101	152	5	10997877
Pubmed	Network organization of the huntingtin proteomic interactome in mammalian brain.	SYT12 CNTNAP1 PFKP SMC2 SUCLA2 FASN EEF2 G3BP2 PYGM GAPDHS PARD3	9.64e-05	621	152	11	22794259
Pubmed	Phosphatidylinositol 4,5-bisphosphate optical uncaging potentiates exocytosis.	CADPS CADPS2	1.13e-04	4	152	2	29068313
Pubmed	Positional cloning of a quantitative trait locus contributing to pain sensitivity: possible mediation by Tyrp1.	MPDZ PTPRD	1.13e-04	4	152	2	20633051
Pubmed	Interaction of the protein tyrosine phosphatase PTPL1 with the PtdIns(3,4)P2-binding adaptor protein TAPP1.	MPDZ PLEKHA2	1.13e-04	4	152	2	14516276
Pubmed	Protein Tyrosine Phosphatase PTPRS Is an Inhibitory Receptor on Human and Murine Plasmacytoid Dendritic Cells.	PTPRF PTPRS	1.13e-04	4	152	2	26231120
Pubmed	Developmentally regulated Ca2+-dependent activator protein for secretion 2 (CAPS2) is involved in BDNF secretion and is associated with autism susceptibility.	CADPS CADPS2	1.13e-04	4	152	2	19238500
Pubmed	RNAi-based analysis of CAP, Cbl, and CrkII function in the regulation of GLUT4 by insulin.	SORBS1 CRK	1.13e-04	4	152	2	15258163
Pubmed	Mitochondrial MTHFD2L is a dual redox cofactor-specific methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase expressed in both adult and embryonic tissues.	MTHFD2 MTHFD2L	1.13e-04	4	152	2	24733394
Pubmed	Oxidized Ca(2+)/calmodulin-dependent protein kinase II triggers atrial fibrillation.	RYR2 MSRA	1.13e-04	4	152	2	24030498
Pubmed	The Asymmetric Cell Division Regulators Par3, Scribble and Pins/Gpsm2 Are Not Essential for Erythroid Development or Enucleation.	SCRIB PARD3	1.13e-04	4	152	2	28095473
Pubmed	A SPRY1 domain cardiac ryanodine receptor variant associated with short-coupled torsade de pointes.	RYR2 TNNI3K	1.13e-04	4	152	2	33664309
Pubmed	Asymmetric localization of Vangl2 and Fz3 indicate novel mechanisms for planar cell polarity in mammals.	CELSR1 SCRIB	1.13e-04	4	152	2	16687519
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	TANC2 BRPF3 USP22 MTHFD2 PHRF1 MAP7 FAM83H ZNF469 SOWAHA AGO3 CADPS WDR6 SUPT7L SCRIB PARD3	1.19e-04	1116	152	15	31753913
Pubmed	Progesterone induced Warburg effect in HEK293 cells is associated with post-translational modifications and proteasomal degradation of progesterone receptor membrane component 1.	PFKP MPRIP PTPRS KNDC1	1.24e-04	58	152	4	31067491
Pubmed	Long-term potentiation modulates synaptic phosphorylation networks and reshapes the structure of the postsynaptic interactome.	CNTNAP1 MPDZ GRIA1 NBEA SORBS1 MPRIP ARC	1.25e-04	251	152	7	27507650
Pubmed	Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.	TPP2 FKBP10 DDX59 CNTNAP1 HNRNPUL1 MAP7 PFKP WNK1 NPEPL1 FASN EEF2 WDR6 PKP3 SYNE2 PLEKHA2 ALPI	1.88e-04	1297	152	16	33545068
Pubmed	Basal cell carcinomas acquire secondary mutations to overcome dormancy and progress from microscopic to macroscopic disease.	PTCH1 LRIG1	1.88e-04	5	152	2	35508126
Pubmed	Mechanosensitive brain tumor cells construct blood-tumor barrier to mask chemosensitivity.	PIEZO1 PTCH1	1.88e-04	5	152	2	36323321
Pubmed	Calcium-dependent activator protein for secretion 2 interacts with the class II ARF small GTPases and regulates dense-core vesicle trafficking.	CADPS CADPS2	1.88e-04	5	152	2	22111578
Cytoband	1p34	GJA9 AGO3 PTPRF	1.64e-04	32	152	3	1p34
GeneFamily	Protein tyrosine phosphatases, receptor type	PTPRT PTPRD PTPRF PTPRS	3.37e-06	21	91	4	813
GeneFamily	EF-hand domain containing\|S100 fused type protein family	FLG FLG2 TCHHL1	4.25e-06	7	91	3	1350
GeneFamily	Fibronectin type III domain containing	PTPRT CNTN6 PTPRD PTPRF PTPRS TNXB	1.57e-04	160	91	6	555
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	IGFBPL1 CNTN6 PTPRD PTPRF LRIG1 PTPRS	1.62e-04	161	91	6	593
GeneFamily	Armadillo repeat containing\|Protein phosphatase 1 regulatory subunits	ARMCX4 ARMC1 PKP3	1.32e-03	43	91	3	409
GeneFamily	Armadillo repeat containing\|Protein phosphatase 1 regulatory subunits	PPP1R12B PHRF1 LMTK2 WNK1 PARD3	2.21e-03	181	91	5	694
GeneFamily	Cadherin related	CDH23 DCHS1	3.24e-03	17	91	2	24
GeneFamily	Lysine acetyltransferases\|ATAC complex\|SAGA complex\|GCN5 related N-acetyltransferases	USP22 SUPT7L	3.24e-03	17	91	2	1059
ToppCell	BAL-Mild-Myeloid-cDC-cDC-cDC_12\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CRPPA MAP7 SMC2 RFTN1 MBLAC1 PYGM LRP5L USP27X	2.38e-07	184	152	8	b8ecf58b3bdb25bcba5efc2d764930bb84ab95c8
ToppCell	BAL-Mild-Myeloid-cDC-cDC-cDC_12\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	CRPPA MAP7 SMC2 RFTN1 MBLAC1 PYGM LRP5L USP27X	2.38e-07	184	152	8	b232a9cc1d14e1a134b037016d437b93921a4a0f
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	DENND2A NHSL2 CDH23 GRIA1 RYR2 PTPRS PARD3 TNXB	3.43e-07	193	152	8	b3ad5ff480d99217f36cc7471e5a96a519ddb409
ToppCell	Adult-Mesenchymal-matrix_fibroblast_1_cell-D231\|Adult / Lineage, Cell type, age group and donor	FKBP10 DENND2A NHSL2 GRIA1 RYR2 MOXD1 PTPRS TNXB	3.43e-07	193	152	8	ef2f456c094e6e3c6ee81e0668c953cb8d0e1c0a
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	TANC2 LMTK2 MAP7 RFTN1 FASN PTPRD PARD3 CADPS2	3.57e-07	194	152	8	97534c8bba895a7913665e03ae4e5c4a6ad71daf
ToppCell	COVID-19-Fibroblasts-Alveolar_FB\|COVID-19 / group, cell type (main and fine annotations)	DENND2A NHSL2 GRIA1 RYR2 MOXD1 PTPRS PARD3 TNXB	3.71e-07	195	152	8	603050beeb33c331d4b2e3fa46cae3f3e0e4bdc7
ToppCell	Children_(3_yrs)-Mesenchymal\|Children_(3_yrs) / Lineage, Cell type, age group and donor	FKBP10 DENND2A NHSL2 GRIA1 RYR2 MOXD1 PTPRS TNXB	3.86e-07	196	152	8	bc94909f9b2dc08a59eef1914148b69720569c8f
ToppCell	Adult-Mesenchymal\|Adult / Lineage, Cell type, age group and donor	FKBP10 DENND2A NHSL2 GRIA1 RYR2 MOXD1 PTPRS TNXB	4.16e-07	198	152	8	26e55b409db2a1637c95fae7c54b0abea1ef550c
ToppCell	Fetal_29-31_weeks-Mesenchymal-vascular_smooth_muscle_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	DENND2A GPR20 PPP1R12B SORBS1 ADCY3 RYR2 MPRIP	2.31e-06	174	152	7	015d3742d3d79a57413a333f00ef2d380a9848dd
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CNTNAP1 CRPPA PTCH1 CLIP3 MOXD1 PTPRS TNXB	2.79e-06	179	152	7	02c90d8306016365ed811f0c63cfb3ac7b85464c
ToppCell	droplet-Lung-21m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TANC2 CENPT NOXA1 ARMCX4 DCHS1 ARC USP27X	3.60e-06	186	152	7	c116cc9f41971622264434ebe29d18e719b0ae19
ToppCell	Adult-Mesenchymal-matrix_fibroblast_1_cell-D175\|Adult / Lineage, Cell type, age group and donor	NHSL2 CDH23 GRIA1 RYR2 MOXD1 PTPRS TNXB	3.73e-06	187	152	7	e15d2967aac248da3517bc2c7d1beaa1d5a0aa7f
ToppCell	Fetal_29-31_weeks-Mesenchymal-vascular_smooth_muscle_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	DENND2A GPR20 PPP1R12B SORBS1 ADCY3 RYR2 MPRIP	4.14e-06	190	152	7	d6b3a92119b210974a32af3fe9875d60eb02761e
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FKBP10 GRIA1 CRPPA PTCH1 RYR2 CLIP3 PTPRS	4.28e-06	191	152	7	b133ee1c0e58d00ddd2e4e05b01fd04947524c18
ToppCell	nucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	DENND2A NHSL2 GRIA1 RYR2 MOXD1 PTPRS TNXB	4.28e-06	191	152	7	6688cee34beee4f151ac17fccbc9c26a9aad72e1
ToppCell	nucseq-Mesenchymal-Fibroblastic-Fibroblastic_2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	DENND2A NHSL2 GRIA1 RYR2 MOXD1 PTPRS TNXB	4.43e-06	192	152	7	99ce9e3c4c50cf64ebb62145f2b5420efa0db309
ToppCell	Mesenchymal-matrix_fibroblast_1_cell\|World / Lineage, Cell type, age group and donor	DENND2A NHSL2 GRIA1 RYR2 MOXD1 PTPRD PTPRS	4.59e-06	193	152	7	acad568621ed677031797b8c2e34dafea798d681
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	NHSL2 CDH23 GRIA1 RYR2 MOXD1 PTPRS TNXB	4.74e-06	194	152	7	e93de9428c986b8943fc169258847c650cfab0e5
ToppCell	IPF-Multiplet-Multiplet\|IPF / Disease state, Lineage and Cell class	MPDZ NBEA PTPRT LRIG1 SYNE2 PARD3 CADPS2	4.91e-06	195	152	7	fce0c29574bb7aab181b9c00feb42681e285d1f2
ToppCell	10x5'v1-week_17-19-Myeloid_neutrophil-granulo-eo/baso/mast\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	CDSN NAALADL1 PRSS57 CRPPA CLIP3 CADPS TTLL10	4.91e-06	195	152	7	f1f48e2e57b2282572959b152aad4bee05143f03
ToppCell	Adult-Mesenchymal-matrix_fibroblast_1_cell\|Adult / Lineage, Cell type, age group and donor	DENND2A NHSL2 GRIA1 RYR2 MOXD1 PTPRS TNXB	4.91e-06	195	152	7	61c9e09fc84d1012e472185d70ad0a06cee30d6e
ToppCell	IPF-Multiplet\|IPF / Disease state, Lineage and Cell class	MPDZ NBEA PTPRT LRIG1 SYNE2 PARD3 CADPS2	4.91e-06	195	152	7	eacc0449ae6f3ad8002268cd061467684c6fb9a7
ToppCell	COVID-19-lung-Fibroblast\|COVID-19 / Disease (COVID-19 only), tissue and cell type	FKBP10 NHSL2 CDH23 GRIA1 RYR2 MOXD1 PTPRS	5.42e-06	198	152	7	3ec01a55ade5e1627258cc3cfebb2c3207a4cb43
ToppCell	Control_saline-Epithelial_alveolar-AT_1-Differentiating_AT1\|Control_saline / Treatment groups by lineage, cell group, cell type	NOXA1 CNTN6 CELSR1 PTPRF SYNE2 ARC ALPI	5.42e-06	198	152	7	85f424cd9bb3117c9e322031024aabb87696ce47
ToppCell	LPS_IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	NOXA1 CNTN6 CELSR1 PTPRF PKP3 SYNE2 ALPI	5.42e-06	198	152	7	b598ab958e31f1e98bd06dc0097b58ac3a3f90a3
ToppCell	COVID-19-lung-Fibroblast\|lung / Disease (COVID-19 only), tissue and cell type	FKBP10 DENND2A NHSL2 RYR2 MOXD1 PTPRD PTPRS	5.42e-06	198	152	7	df3de77216f5c5d6141ec44d01c56b942f611838
ToppCell	facs-Brain_Non-Myeloid-Striatum-3m-Macroglial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACOT7 MAP7 SLC6A9 CLIP3 PTPRD KNDC1 PCBP4	5.42e-06	198	152	7	27f0654fb0857e93f030e1a4b1c307b31576bbcd
ToppCell	facs-Brain_Non-Myeloid-Striatum-3m-Macroglial-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACOT7 MAP7 SLC6A9 CLIP3 PTPRD KNDC1 PCBP4	5.42e-06	198	152	7	fef9a4c96450078527b94d25e681410e4ea01b13
ToppCell	LPS_IL1RA_TNF-Epithelial_alveolar-AT_1\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	NOXA1 CNTN6 CELSR1 PTPRF PKP3 SYNE2 ARC	5.61e-06	199	152	7	1c70e7d6bd25980e1b92aa1cac3f3c95d9651b4b
ToppCell	LPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	FKBP10 DENND2A PTCH1 RYR2 MOXD1 PTPRD TNXB	5.61e-06	199	152	7	a7dd94b172c973a131a6792f8ccd9bfe44d984ac
ToppCell	LPS_IL1RA-Epithelial_alveolar-AT_1\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	NOXA1 CNTN6 CELSR1 PTPRF PKP3 SYNE2 ALPI	5.61e-06	199	152	7	a270630626df614f8605abddb7dee7c4d74f6149
ToppCell	Tracheal-10x5prime-Stromal-Myofibroblastic-Muscle_smooth_systemic_arterial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	GPR20 MTHFD2 PPP1R12B SORBS1 RYR2 ARC KCNT1	5.61e-06	199	152	7	c2903b1a4b91e94bbdaa909bacefe901255cf248
ToppCell	Biopsy_Control_(H.)-Mesenchymal-Fibroblasts\|Biopsy_Control_(H.) / Sample group, Lineage and Cell type	FKBP10 CILP CLIP3 MOXD1 LOXL1 PRRG3 TNXB	5.79e-06	200	152	7	8d75ce89393df452defacf2ec9a5bd4b7708afbb
ToppCell	Bronchial-NucSeq-Stromal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DENND2A NHSL2 GRIA1 RYR2 MOXD1 PTPRS TNXB	5.79e-06	200	152	7	389cc775c8419d90fb77cd794376d2160a7bf44e
ToppCell	Bronchial-NucSeq-Stromal-Fibroblastic-Fibro_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DENND2A NHSL2 GRIA1 RYR2 MOXD1 PTPRS TNXB	5.79e-06	200	152	7	e8462395fee0a532d1e7ec7f1795f28c42af6541
ToppCell	LPS_IL1RA_TNF-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	NOXA1 CNTN6 CELSR1 PTPRF PKP3 SYNE2 ARC	5.79e-06	200	152	7	ddfb1f006365bf16203ee49f20200f68220cc288
ToppCell	LPS_anti-TNF-Epithelial_alveolar-AT_1\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	NOXA1 CNTN6 CELSR1 PTPRF PKP3 SYNE2 ALPI	5.79e-06	200	152	7	8683445ad5b70748c4a1f12eb77d47623085147e
ToppCell	Parenchymal-NucSeq-Stromal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DENND2A NHSL2 GRIA1 RYR2 MOXD1 PTPRS TNXB	5.79e-06	200	152	7	cf433f9b43d7db07acaf70e060f8f77c974e72f3
ToppCell	Bronchial-NucSeq-Stromal-Fibroblastic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DENND2A NHSL2 GRIA1 RYR2 MOXD1 PTPRS TNXB	5.79e-06	200	152	7	cae972324d1dfea6efeaf6013f265c7c6bb48db4
ToppCell	LPS_only-Epithelial_alveolar-AT_1\|LPS_only / Treatment groups by lineage, cell group, cell type	NOXA1 CNTN6 PTPRF PKP3 SYNE2 ARC CADPS2	5.79e-06	200	152	7	9a6ae40f3e17cd44ee5fd73260713b920aa2ea15
ToppCell	Parenchymal-NucSeq-Stromal-Fibroblastic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DENND2A NHSL2 GRIA1 RYR2 MOXD1 PTPRS TNXB	5.79e-06	200	152	7	311fab076f2ceb258e3970eb21e39344b894042a
ToppCell	Parenchymal-NucSeq-Stromal-Fibroblastic-Fibro_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DENND2A NHSL2 GRIA1 RYR2 MOXD1 PTPRS TNXB	5.79e-06	200	152	7	34f52003988ce6329d8deeee1ab875fa77e01e9d
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Crhr2_Efemp1\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	FAM114A1 CNTNAP3 SMC2 TNNI3K MOXD1 DCHS1	7.37e-06	136	152	6	e3a2425ba5ef538dbacab1479e682837ae42a888
ToppCell	facs-Marrow-B-cells-24m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CNTNAP3 FLG2 GOT1L1 PTPRF PTPRS TCHHL1	9.82e-06	143	152	6	6df16bf0324661cd9707df69cb39f4b5498d6d49
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Crhr2_Efemp1\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	FAM114A1 INHBB CNTNAP3 SMC2 TNNI3K MOXD1	1.50e-05	154	152	6	a2adaa4a6cd8708cd579b8efbeb4ff2131c5482e
ToppCell	10x5'v1-week_14-16-Hematopoietic-HSC/MPP_and_pro-LMPP\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	PRSS57 MAP7 TRBV20-1 PKP3 GAPDHS TTLL10	1.61e-05	156	152	6	96747447ba7dc2c10079cee44394b19ce60b2f41
ToppCell	Adult-Mesenchymal-chondrocyte-D231\|Adult / Lineage, Cell type, age group and donor	FKBP10 DENND2A CILP RYR2 LOXL1 PKP3	2.14e-05	164	152	6	2ba57dce5f69a88f0d1e450b9780425e2d9ca7d4
ToppCell	E16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NHSL2 ADCY3 COCH PTPRS LOXL1 TNXB	2.21e-05	165	152	6	4e13fccd32029e2879e85f8966e582a46c09e4aa
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c03-GZMK\|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)	RUSC1 ZNF213 ATG2A WNK1 SYNE2 PCDHGA8	2.29e-05	166	152	6	9e916fc1858573358e1eb5e3789b2c9f8ef74476
ToppCell	facs-Lung-EPCAM-24m-Endothelial-Lymphatic_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TANC2 FKBP10 DENND2A CNTNAP3 CELSR1 PRRG3	2.37e-05	167	152	6	961e722442d786ab15d1e490941d2be265a9057a
ToppCell	facs-Lung-EPCAM-24m-Endothelial-endothelial_cell_of_lymphatic_vessel\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TANC2 FKBP10 DENND2A CNTNAP3 CELSR1 PRRG3	2.37e-05	167	152	6	3760efc35d4e7e9c2da1a20f9795ddea397e2206
ToppCell	TCGA-Liver-Primary_Tumor-Hepatocellular_Carcinoma-Hepatocellular_Carcinoma-6\|TCGA-Liver / Sample_Type by Project: Shred V9	GPR20 KIF26A PPP1R12B ADCY3 CLIP3 TNXB	2.53e-05	169	152	6	e992530776cab922d0360b275fb9cb8bd0017b06
ToppCell	wk_08-11-Mesenchymal-Myofibro_&_SMC-Myofibro_2\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	NLRX1 MPDZ PTCH1 ADCY3 MSRA USP27X	2.62e-05	170	152	6	fefb07a7e308b620f946b9ff2b01e1796446fe38
ToppCell	facs-Heart-LV-24m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAM184B GPR20 PPP1R12B SORBS1 MBLAC1 SOWAHA	2.98e-05	174	152	6	197686570cec6d96a92e77e6409325d3bfe6f991
ToppCell	facs-Heart-LV-24m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAM184B GPR20 PPP1R12B SORBS1 MBLAC1 SOWAHA	2.98e-05	174	152	6	2eee7b5471672b439f95eba11494c2adf8cb7006
ToppCell	facs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l20-1\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NKX3-2 ADCY3 PTPRS DCHS1 GAPDHS TNXB	2.98e-05	174	152	6	1d157f7a919c8246e83d8060d2a0017c6c781ef3
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	GPR20 MTHFD2 SORBS1 ADCY3 RYR2 PYGM	3.08e-05	175	152	6	316f2ea930437bf1243b1c0f45e6bd864112c6f2
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	GPR20 MTHFD2 SORBS1 ADCY3 RYR2 PYGM	3.08e-05	175	152	6	a9f08e1e4c2997dcdd3e5d92daac480da19100b8
ToppCell	3'-Child09-12-SmallIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PPP1R12B CNTNAP3 NBEA SORBS1 ARMCX4 PARD3	3.18e-05	176	152	6	a8875b4ba4abf6625cdeb67bf544ce1573c59060
ToppCell	356C-Fibroblasts-Fibroblast-G\|356C / Donor, Lineage, Cell class and subclass (all cells)	PCDHGA3 GRIA1 RYR2 MOXD1 PTPRD PTPRS	3.28e-05	177	152	6	8220cc2fc0ee8764a67a3be51d75248be2453040
ToppCell	356C-Fibroblasts-Fibroblast-G-\|356C / Donor, Lineage, Cell class and subclass (all cells)	PCDHGA3 GRIA1 RYR2 MOXD1 PTPRD PTPRS	3.28e-05	177	152	6	7617270f49cd6b7ba66db72d20560cee985012b2
ToppCell	3'-Distal_airway-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DENND2A PCDHGA3 GRIA1 MOXD1 LOXL1 TNXB	3.39e-05	178	152	6	09475e522dc1b8cf9ff1c25de5d1e3082b162948
ToppCell	3'-Distal_airway-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts-Peribronchial_fibroblasts_L.2.1.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DENND2A PCDHGA3 GRIA1 MOXD1 LOXL1 TNXB	3.39e-05	178	152	6	35de8f791b0e78a6caf52ff095f05e204a59e828
ToppCell	3'-Distal_airway-Mesenchymal-Fibroblastic-fibroblastic_type_2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DENND2A PCDHGA3 GRIA1 MOXD1 LOXL1 TNXB	3.39e-05	178	152	6	000d25f3f13cc76cf39c46c312c6fafc2ea4f368
ToppCell	TCGA-Adrenal-Primary_Tumor-Pheochromocytoma-Pheochromocytoma-1\|TCGA-Adrenal / Sample_Type by Project: Shred V9	KIF26A NBEA SORBS1 RAB3GAP1 CADPS ARC	3.50e-05	179	152	6	431e1b29015ec817f778499106d24b19cfc825ae
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FKBP10 CRPPA PTCH1 RYR2 PTPRS TNXB	3.95e-05	183	152	6	7eae9b3b4d1c9b135fa7cff348393d4adec474b4
ToppCell	droplet-Limb_Muscle-Pre-Sort-18m-Mesenchymal\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	XIRP1 GPR20 CILP RYR2 LOXL1 TNXB	4.08e-05	184	152	6	c9d7ec17cc5b7ba1b1e721ca392746e8f4a3d41f
ToppCell	390C-Fibroblasts-Fibroblast-F\|390C / Donor, Lineage, Cell class and subclass (all cells)	FAM114A1 CILP CLIP3 MOXD1 LOXL1 TNXB	4.20e-05	185	152	6	2c1f14f77faeee2acb388d997c5a27a7fef79be1
ToppCell	COVID-19-Epithelial_cells-Airway_club\|COVID-19 / group, cell type (main and fine annotations)	MAP7 CELSR1 PTPRD LRIG1 PARD3 CADPS2	4.20e-05	185	152	6	cfe6fd73d817e173fe803bc1683c291d9bcb8608
ToppCell	390C-Fibroblasts-Fibroblast-F-\|390C / Donor, Lineage, Cell class and subclass (all cells)	FAM114A1 CILP CLIP3 MOXD1 LOXL1 TNXB	4.20e-05	185	152	6	37db8e0b1f59274227f6fc2362167eb44bd080ef
ToppCell	BAL-Mild-cDC_12\|Mild / Compartment, Disease Groups and Clusters	CRPPA MAP7 MBLAC1 PYGM LRP5L USP27X	4.20e-05	185	152	6	e867ed55ab0df018f14bca824da09d36d83e12f9
ToppCell	Children_(3_yrs)-Mesenchymal-pericyte_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	DENND2A GPR20 ADCY3 RYR2 PTPRD PARD3	4.46e-05	187	152	6	86250acf088ec0c4800a0dfa031b0d4f7e52c342
ToppCell	droplet-Lung-18m-Endothelial-arterial_endothelial\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CENPT KIF26A ARMCX4 COCH RIPOR1 HYAL2	4.46e-05	187	152	6	12129e02638c20d9b7c1c6e512d48bfd966e1029
ToppCell	Control-Fibroblasts-Alveolar_FB\|Control / group, cell type (main and fine annotations)	DENND2A NHSL2 GRIA1 RYR2 PTPRS TNXB	4.46e-05	187	152	6	92d468dde81125d51daf7abd4703741abe1ab91c
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT2\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	NOXA1 CNTN6 CELSR1 PTPRF SYNE2 CADPS2	4.46e-05	187	152	6	58d48128547ee3513d0bf7f78e61b76b1c472ca9
ToppCell	droplet-Lung-18m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CENPT KIF26A ARMCX4 COCH RIPOR1 HYAL2	4.46e-05	187	152	6	83930ef55191eff9006113feaeabb3c2fa21fd05
ToppCell	Children_(3_yrs)-Mesenchymal-pericyte_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	DENND2A GPR20 ADCY3 RYR2 SLC6A9 RFTN1	4.60e-05	188	152	6	ee151792c7ac9afe820f1a281c6dab383799f358
ToppCell	wk_15-18-Endothelial-Lymph_endothelial-SCG3+_lymphatic_endothelial\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	PIEZO1 CNTNAP3 COCH RAB3IL1 TNXB HYAL2	4.73e-05	189	152	6	f0418851ad4042c4cd87c8729e4f0d43bdf8fccb
ToppCell	LPS_only-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DENND2A PTCH1 RYR2 MOXD1 PTPRD PTPRS	4.73e-05	189	152	6	2a22b9fae70afb3dab8476f9c00e48a4df756410
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FKBP10 CRPPA PTCH1 RYR2 CLIP3 PTPRS	4.73e-05	189	152	6	45e588b2a4ad9e3ff74e22d9d627ed3571f3b8b8
ToppCell	Control-Fibroblasts\|Control / group, cell type (main and fine annotations)	DENND2A NHSL2 GRIA1 RYR2 MOXD1 TNXB	4.87e-05	190	152	6	3a42a9b98d954685d38a741f44545898d0e3e9ce
ToppCell	Control-Stromal_mesenchymal\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FKBP10 CRPPA PTCH1 RYR2 PTPRS TNXB	5.02e-05	191	152	6	14057205ddb9b4bbc582d1358d13cf36d979a61b
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FKBP10 GPR20 SORBS1 ADCY3 RYR2 MOXD1	5.02e-05	191	152	6	04c4d454b57e29a8d1dcdeb4678ce71bdc29b77b
ToppCell	Mesenchymal-vascular_smooth_muscle_cell\|World / Lineage, Cell type, age group and donor	DENND2A GPR20 PPP1R12B SORBS1 RYR2 KCNT1	5.02e-05	191	152	6	fd89fbc62aa1c73e0f659991e3bd726a0c97bd68
ToppCell	droplet-Kidney-nan-3m-Mesenchymal-Stroma____fibroblast\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CILP CLIP3 MOXD1 KRTDAP LOXL1 TNXB	5.02e-05	191	152	6	d1205aab0937f2becfcd239610e9b78fb8a0c886
ToppCell	PND28-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TANC2 RBPJL ACOT7 FASN PTPRF PRRG3	5.17e-05	192	152	6	7ccdb977320d09f21e70e7718ead73eeb56d0c48
ToppCell	PND28-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TANC2 RBPJL ACOT7 FASN PTPRF PRRG3	5.17e-05	192	152	6	f206c015f091234e2c86dfa66926e97b2ea99690
ToppCell	Adult-Epithelial\|Adult / Lineage, Cell type, age group and donor	MAP7 CELSR1 PTPRF LRIG1 PARD3 CADPS2	5.17e-05	192	152	6	efb962a5fd3b9bdfd8cf8d13c435e29c8271713e
ToppCell	PND28-Epithelial-Epithelial_Alveolar\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TANC2 RBPJL ACOT7 FASN PTPRF PRRG3	5.17e-05	192	152	6	69963e8dc6d6368243e61da133484eb23225625a
ToppCell	PND28-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TANC2 RBPJL ACOT7 FASN PTPRF PRRG3	5.17e-05	192	152	6	bfc68af68fdb99ddfe4add49671e4b4c26e6f962
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT2-AT2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	TANC2 MAP7 FASN PTPRD PARD3 CADPS2	5.32e-05	193	152	6	fd4d3c0d7caf8a2fff5b3d901fc28d19a8163cdf
ToppCell	Epithelial-club_cell\|World / Lineage, Cell type, age group and donor	NBEA MAP7 CELSR1 PTPRD LRIG1 CADPS2	5.32e-05	193	152	6	2bdd09004fa433550958ec42ba4b06271a4aaf7c
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	NHSL2 GRIA1 RYR2 MOXD1 PTPRS TNXB	5.32e-05	193	152	6	99525545552b371c86b18b6ea6f4897dc6e9a9ec
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	TANC2 MAP7 FASN PTPRD PARD3 CADPS2	5.32e-05	193	152	6	f3cc7cfdbc164a4ed42f87647111522b7d393bcb
ToppCell	10x5'v1-week_14-16-Myeloid_neutrophil-granulo-eo/baso/mast-mast_cell\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	CDSN NAALADL1 PRSS57 MTHFD2 CADPS TTLL10	5.47e-05	194	152	6	d8f367beab16a3186821e42311947b6c9e99978c
ToppCell	facs-Bladder-nan-3m-Epithelial-nan\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACOT7 FAM83H EEF2 PTPRF KRTDAP PARD3	5.47e-05	194	152	6	e74cd8cf3763f6adbfd1c269a886a806049714cf
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SORBS1 PTCH1 RFTN1 MOXD1 LOXL1 TNXB	5.47e-05	194	152	6	cf0244a29934e515446ac917d3c30672b460fb04
ToppCell	10x_3'_v2v3-Neoplastic-Differentiated-like-AC-like-AC-like-B\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	DENND2A GRIA1 PTPRT LRIG1 PTPRS ARC	5.47e-05	194	152	6	68d15917ae222cba0ad9e716d29eebb6c5f00f69
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SORBS1 PTCH1 ADCY3 RFTN1 MOXD1 TNXB	5.47e-05	194	152	6	e03ba6caed59fa64d4d9b042593469d4a6a3dc10
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SORBS1 PTCH1 RFTN1 MOXD1 LOXL1 TNXB	5.47e-05	194	152	6	ba7f971fb9a19423602da60770f23d9fead4a451
Disease	NEURAL TUBE DEFECTS, SUSCEPTIBILITY TO	CELSR1 SCRIB PARD3	6.53e-06	8	146	3	C3891448
Disease	azoospermia (implicated_via_orthology)	PTPRD PTPRF PTPRS	3.18e-04	27	146	3	DOID:14227 (implicated_via_orthology)
Disease	Congenital muscular dystrophy (disorder)	CRPPA SYNE2	3.60e-04	6	146	2	C0699743
Disease	peeling skin syndrome (is_implicated_in)	CDSN FLG2	3.60e-04	6	146	2	DOID:0060283 (is_implicated_in)
Disease	severe acute respiratory syndrome, COVID-19	ZNF213 SUCLA2 CNTN6 MSRA PTPRD CADPS LRP5L PARD3 CADPS2	4.03e-04	447	146	9	EFO_0000694, MONDO_0100096
Disease	childhood trauma measurement, alcohol consumption measurement	TANC2 PCDHGA3 PTPRD PCDHGA8	4.32e-04	71	146	4	EFO_0007878, EFO_0007979
Disease	risk-taking behaviour	CDSN KIF26A CDH23 GRIA1 PTCH1 RYR2 MSRA TNNI3K PTPRF CADPS CADPS2 TNXB	4.35e-04	764	146	12	EFO_0008579
Disease	hereditary lymphedema (is_implicated_in)	PIEZO1 CELSR1	5.02e-04	7	146	2	DOID:0050580 (is_implicated_in)
Disease	joint hypermobility measurement	PIEZO1 MSRA LOXL1	5.81e-04	33	146	3	EFO_0007905
Disease	autosomal recessive intellectual developmental disorder (implicated_via_orthology)	CNTNAP1 CNTNAP3	6.68e-04	8	146	2	DOID:0060308 (implicated_via_orthology)
Disease	disease recurrence, malaria	PTPRT KNDC1	6.68e-04	8	146	2	EFO_0001068, EFO_0004952
Disease	glioblastoma (implicated_via_orthology)	USP22 USP27X	8.56e-04	9	146	2	DOID:3068 (implicated_via_orthology)
Disease	vital capacity	FAM184B DENND2A CAND2 PIEZO1 SIX4 PTCH1 ADCY3 MAGEF1 RYR2 PTPRD LOXL1 FOLH1B RIPOR1 PARD3 TNXB	1.24e-03	1236	146	15	EFO_0004312
Disease	BMI-adjusted waist-hip ratio, sex interaction measurement	LEMD3 CRPPA PTPRD	1.27e-03	43	146	3	EFO_0007788, EFO_0008343
Disease	Cognitive impairment	PTPRT RYR2	1.30e-03	11	146	2	HP_0100543
Disease	selective IgA deficiency disease	C22orf42 CDH23 FASN	1.54e-03	46	146	3	EFO_1001929
Disease	Emery-Dreifuss muscular dystrophy (implicated_via_orthology)	LEMD3 SYNE2	1.55e-03	12	146	2	DOID:11726 (implicated_via_orthology)
Disease	estradiol measurement	PPP1R12B C2CD4C CNTN6 CELSR1	2.21e-03	110	146	4	EFO_0004697
Disease	Drug habituation	FAM184B MSRA WDR11 CADPS2	2.60e-03	115	146	4	C0013170
Disease	Drug abuse	FAM184B MSRA WDR11 CADPS2	2.60e-03	115	146	4	C0013146
Disease	Prescription Drug Abuse	FAM184B MSRA WDR11 CADPS2	2.60e-03	115	146	4	C4316881
Disease	Substance-Related Disorders	FAM184B MSRA WDR11 CADPS2	2.60e-03	115	146	4	C0236969
Disease	Drug Use Disorders	FAM184B MSRA WDR11 CADPS2	2.60e-03	115	146	4	C0013222
Disease	Drug Dependence	FAM184B MSRA WDR11 CADPS2	2.60e-03	115	146	4	C1510472
Disease	Substance Dependence	FAM184B MSRA WDR11 CADPS2	2.60e-03	115	146	4	C0038580
Disease	Substance Use Disorders	FAM184B MSRA WDR11 CADPS2	2.60e-03	115	146	4	C0038586
Disease	Organic Mental Disorders, Substance-Induced	FAM184B MSRA WDR11 CADPS2	2.60e-03	115	146	4	C0029231
Disease	Substance abuse problem	FAM184B MSRA WDR11 CADPS2	2.68e-03	116	146	4	C0740858
Disease	attention deficit hyperactivity disorder, Cannabis use	SLC6A9 PTPRF	3.53e-03	18	146	2	EFO_0003888, EFO_0007585
Disease	optic disc size measurement	TANC2 DENND2A PTCH1 RFTN1 CADPS	3.61e-03	205	146	5	EFO_0004832
Disease	lysophosphatidylcholine 20:5 measurement	MTHFD2L RAB3IL1	3.93e-03	19	146	2	EFO_0010364
Disease	glaucoma (is_marker_for)	RFTN1 PTPN11	4.36e-03	20	146	2	DOID:1686 (is_marker_for)
Disease	exercise test	RYR2 PTPRD	4.36e-03	20	146	2	EFO_0004328
Disease	response to COVID-19 vaccine, SARS-CoV-2 neutralizing antibody measurement	LMTK2 PTPRD	4.36e-03	20	146	2	EFO_0803359, EFO_0803362
Disease	selenium measurement, response to dietary selenium supplementation	CNTN6 MSRA	4.36e-03	20	146	2	EFO_0006331, EFO_0600021
Disease	eye morphology measurement	CDH23 PFKP PTPRT MPRIP TTLL10	4.67e-03	218	146	5	EFO_0007858
Disease	disease of metabolism (implicated_via_orthology)	PFKP PTPN11	4.80e-03	21	146	2	DOID:0014667 (implicated_via_orthology)
Disease	breast size	CCDC117 INHBB CADPS	4.90e-03	69	146	3	EFO_0004884

Protein segments in the cluster

Peptide	Gene	Start	Entry
TNGGAEPRLGFSDIH	TBC1D12	256	O60347
RPDDANVAGNVHGGT	ACOT7	61	O00154
HAAAGPDGQLGTVEQ	BARGIN	31	Q6ZT62
QDVEGHGVNPSVSGL	CCDC117	106	Q8IWD4
TVVQHGGPDAVTLRG	CNTNAP3	631	Q9BZ76
RPGHTTVSAGGVLND	CNTNAP1	246	P78357
VENRVGGVHTVGDSG	GOT1L1	96	Q8NHS2
SESARHTVSVGVGGP	ARC	141	Q7LC44
LFGQHGEREPSSGDV	GPR20	311	Q99678
QDKAVSRVGSHPEGG	ARMC1	251	Q9NVT9
RVLENGEDHGVAGSP	BRPF3	946	Q9ULD4
VSSGLVRGSHGEPDA	CELSR1	2776	Q9NYQ6
ASQDGQDTIRGHPGS	FLG	1481	P20930
ASQEGQDTIRGHPGS	FLG	3426	P20930
AEGSHVSGQSNGRDP	AGO3	826	Q9H9G7
VVDQHGSGAPGVVQG	CDSN	256	Q15517
NIGPTEDVQASAHGG	C22orf42	101	Q6IC83
ESGQARGEHTVHVGP	C2CD4C	291	Q8TF44
EAIDNGPVGKRHTGT	CDH23	1071	Q9H251
GAGTRHSAQPQIVAG	ARMCX4	1021	Q5H9R4
VRVEHSPGDGERGVA	ATG2A	176	Q2TAZ0
SVSALIGGNQEGSHP	CRK	196	P46108
GHRESPGALVETSAG	RAB3IL1	31	Q8TBN0
GQDQAHQAGETGPTV	RBPJL	106	Q9UBG7
EQPEVLVTGAGRGHA	RAB3GAP1	876	Q15042
RAGTHQGPLDAETEV	NOXA1	241	Q86UR1
VEGEAVQNGPASHSR	RFTN1	531	Q14699
QDSGGRLVGVPASHF	PCDHGA8	726	Q9Y5G5
AGTEPGRHPQAVAAV	CRPPA	36	A4D126
HGFGPITTDIREGQT	MSRA	186	Q9UJ68
NHIGGGAFSVDSPRI	LEMD3	391	Q9Y2U8
TQFPSEEAREGGGVH	MON1B	21	Q7L1V2
HGNRPDGIGTVTVEE	CADPS	761	Q9ULU8
GPRIVLAAAGGVSHD	PMPCB	236	O75439
AEGAGERHVTITGSP	PCBP4	281	P57723
VVQARDGGAHPELGS	DCHS1	331	Q96JQ0
PIVSPRAVHAGGTNG	DCHS1	2086	Q96JQ0
SIVPERHGTTHGQTG	FLG2	1686	Q5D862
SAGRSVHGGVPQNVS	HYAL2	91	Q12891
AQERVGGVGPADTHE	MPRIP	556	Q6WCQ1
GGHDGETRAPTASQE	MAGEF1	21	Q9HAY2
HRGGDGAVRSETAPD	MAP7	11	Q14244
VVRTEGGPQANGHIE	LRIG1	856	Q96JA1
FTQVEATRGGGHPAR	NLRC3	106	Q7RTR2
EEVAQRSHAVGSPGS	HEMK1	146	Q9Y5R4
DVHGEQETEGRSSPG	KATNIP	241	O60303
LDGHASPGADGQERV	INHBB	126	P09529
SVEGPLTGHGESIQD	KIAA1109	1436	Q2LD37
DHIIATEERGGPGQA	FAM184B	776	Q9ULE4
DLQGTEHRPTQSGGG	KCNT1	656	Q5JUK3
VGSDTVRGQARHPFG	LOXL1	106	Q08397
GGQLAEVHSVSPEQG	DDX59	66	Q5T1V6
GGTASLEEGPQHVTV	KIF27	461	Q86VH2
ESSAEQPRKGGAQHG	PCNX2	1906	A6NKB5
VLHSAQGATLGGPEE	KRTDAP	16	P60985
AAPVHAGERATGFGV	NPEPL1	466	Q8NDH3
GHVQRGGTPSAFDRI	PFKP	306	Q01813
GGIDPQSGAAVVHET	FOLH1B	76	Q9HBA9
RETDFGVGVRDHPGQ	NPIPB8	51	E9PQR5
GDHVNIAVQVRGGPS	IGFBPL1	206	Q8WX77
GGRRDAAPAHGQSIE	PHRF1	691	Q9P1Y6
KVVGTNPHADRNGGA	LRP5L	216	A4QPB2
GHDSGVNVGEERPPT	KIF26A	1591	Q9ULI4
PVIVISDAGDGHRGT	LMTK2	1071	Q8IWU2
GHRGTEVTPETFTAG	LMTK2	1081	Q8IWU2
DAGPVVVHCSAGIGR	PTPN11	451	Q06124
GGSGVSATPAQRDHL	NLRX1	336	Q86UT6
HVEVGSQAGADGTRP	OXLD1	61	Q5BKU9
DAGPIVVHCSAGVGR	PTPRS	1581	Q13332
EAGPIVVHCSAGAGR	PTPRT	1076	O14522
EGQGQTASHGELLTP	CAMK1	326	Q14012
HGGEDVAVFARGPQA	ALPI	451	P09923
VLVASDGGDPVHSGN	PCDHGA3	211	Q9Y5H0
RTEDDGVGPRGAHVS	NKX3-2	161	P78367
AHGESGARGVPGSAV	FKBP10	461	Q96AY3
GGGSGSEVSQRVHPS	DENND2A	206	Q9ULE3
GHRSIPGVAIDGENN	GJA9	386	P57773
VHGGVDASGKPQEAV	G3BP2	41	Q9UN86
GAQGPSRVEEAEGHT	CENPT	351	Q96BT3
EAGGIPGRVHISQST	ADCY3	446	O60266
HGNRPDGIGTVSVEE	CADPS2	726	Q86UW7
VVAPVNIHGGGGSRS	CNTN6	701	Q9UQ52
GVAPGDVTLVVGTHG	MBLAC1	101	A4D2B0
TPGHGGQRDVSVVVA	MBLAC1	166	A4D2B0
SARGAQPTVEAGVAH	DENND4B	966	O75064
PVRNGESHSREGLAG	KNDC1	266	Q76NI1
ADAIHRGGGQIIPTA	EEF2	711	P13639
APSGQEREDHGLETG	C9orf40	81	Q8IXQ3
DQPTGKHDGSVFGVR	CLIP3	451	Q96DZ5
RDPGGGAGAITVASH	FAM83H	746	Q6ZRV2
GSGENGRVVSHDFPK	GRIA1	871	P42261
VDGGINPDSLRGTHT	FASN	91	P49327
GRGAHQNIIPASTGA	GAPDHS	271	O14556
SLAEVGQVAGPGHQR	CAND2	846	O75155
AAVHRGVISNSGGPV	COCH	76	O43405
GIGTEGPHVGLVQAS	COCH	196	O43405
EGSLHARDPVGGTTE	RYR2	1801	Q92736
RETDFGVGVRDHPGQ	NPIPB6	51	E9PJ23
DGVAGEHSQIPNGSR	PRDM4	216	Q9UKN5
DPAVASRGGQLHAAG	SCRIB	96	C0HLS1
RIHGVNSGSSEGAQP	FAM114A1	161	Q8IWE2
QDGPITVHCSAGVGR	PTPRF	1831	P10586
DNSRVEPVGHADTGL	PARD3	246	Q8TEW0
QDGPISVHCSAGVGR	PTPRD	1836	P23468
RPGHINEEVETEGGS	HNRNPUL1	56	Q9BUJ2
SPETAVAGVGHELGT	MINDY2	111	Q8NBR6
GRHGTAAEEGAQERP	RUSC1	756	Q9BVN2
DGQEGSEPGSHTILR	PLEKHA2	166	Q9HB19
SSDGRGDNVGHVIIG	SYT12	376	Q8IV01
GDNVGHVIIGPSASG	SYT12	381	Q8IV01
PEGQDVTSGFSRIGH	TRMT5	191	Q32P41
EGTITTSENRGGDPH	SYNE2	1051	Q8WXH0
VPEGVHGRVAVGQDA	NHSL2	321	Q5HYW2
DGAHERPGGDATVTI	MTHFD2	216	P13995
DILGNSDRPGSGVHV	NBEA	1036	Q8NFP9
GAQIIGGHEVTPHSR	PRSS57	31	Q6UWY2
GAGGPAHQVIVEATE	PTCH1	1246	Q13635
AHREVAGGAAVGLSP	SIX4	31	Q9UIU6
GASGDGVRTETAPHI	SLC5A9	11	Q2M3M2
GIVGDGRPVQHVQAS	TANC2	1666	Q9HCD6
PQESEEGNVSGHGVL	SUPT7L	346	O94864
TPANFLDVGGGATVH	SUCLA2	341	Q9P2R7
SEPAHSVNGEGGVLA	SLX4	131	Q8IY92
PAGSTGQVVHGSPRE	CILP	101	O75339
GAGGTVHQPGFIVVE	GTF2H4	296	Q92759
VPGHSGFIGNEEADR	RNASEH1	261	O60930
PVSFHERGGVGSRAD	PKP3	161	Q9Y446
REGSGAQGEAEVRHP	TNRC18	666	O15417
TGTLIQGHEPEAGEA	ZNF516	86	Q92618
GTNVVSEPREEGSAH	UBXN6	101	Q9BZV1
GRESSVNGESHIPGI	USP27X	246	A6NNY8
LSPGSEGNVVNGESH	USP22	341	Q9UPT9
AGGDVSVVTGHQQEP	MPDZ	1946	O75970
ASADIVVGGVAHGRP	MOXD1	71	Q6UVY6
AIGDVVNHDPAVGDR	PYGM	626	P11217
RSGAPVDVNARSHGG	SOWAHA	371	Q2M3V2
EAGDSVGNVHEGLTP	ZBTB41	336	Q5SVQ8
PGSEAEQTERHRGGE	SORBS1	1186	Q9BX66
HGGQRVGPVSAVGLT	TNXB	2266	P22105
AVRVPGHEDGVTISG	TNXB	2671	P22105
GLHEGQRVGPVSTVG	TNXB	3236	P22105
RDPVQVAAPSDHGVG	TPP2	536	P29144
GVDVSRVADHGPGLA	SLC6A9	426	P48067
PGLTAHVVSAGGRAE	WDR6	796	Q9NNW5
VFDPHGTLSGGARSQ	SMC2	656	O95347
GEHERPGGDATVTIA	MTHFD2L	231	Q9H903
ENGVSPGGTDNHASV	ZNF469	1976	Q96JG9
REQHPGSGEEAVALV	ZNF213	106	O14771
EGPEEAAAGRSHVVQ	PIEZO1	1491	Q92508
EEVNTGRQEGSEAPH	ZNF142	661	P52746
GGDQTHPELEGTAVS	TCHHL1	451	Q5QJ38
DGNENVPSSSGRHEG	WNK1	1081	Q9H4A3
IGQSAIAGEEHPRGS	WDR11	431	Q9BZH6
QSFAGVLGSHERGPS	RIPOR1	21	Q6ZS17
ADVNVSGEVGDRPLH	TNNI3K	191	Q59H18
NGAGGTTLAVLHPER	PVRIG	81	Q6DKI7
GTEQSGTGNRHPAQE	TTLL10	641	Q6ZVT0
RGTVHSQGEPSGHRE	PRRG3	136	Q9BZD7
DSIGQGEVLAHGSPS	XIRP1	451	Q702N8
GEVLAHGSPSREEGT	XIRP1	456	Q702N8
GSGLGAVVSQHPSRV	TRBV20-1	11	A0A075B6N2
HRTEENVTGEQGGPD	NAALADL1	131	Q9UQQ1
HGASVGIVNSEGEVP	PPP1R12B	146	O60237