Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionubiquitin conjugating enzyme binding

RNF19A RNF19B MARCHF7 ANKIB1

1.24e-04361434GO:0031624
GeneOntologyMolecularFunctionubiquitin-like protein conjugating enzyme binding

RNF19A RNF19B MARCHF7 ANKIB1

2.28e-04421434GO:0044390
GeneOntologyMolecularFunctiontranscription coactivator activity

DCAF6 TCF20 ZXDA MED24 KMT2C BRCA1 PER2 KAT6B MED13

3.42e-043031439GO:0003713
GeneOntologyBiologicalProcessmicrotubule cytoskeleton organization

STK36 GIT1 RNF19A EML4 KIF4A PARD3B CLASP2 C10orf90 CEP350 BRCA1 PARD6A TTLL4 NAV1 RACGAP1 DNAI4 KIF4B PHLDB2 PCNT

2.87e-0672014418GO:0000226
GeneOntologyBiologicalProcessmicrotubule-based process

STK36 GIT1 RNF19A EML4 KIF4A PARD3B CLASP2 C10orf90 CEP350 BORCS5 BRCA1 PARD6A TTLL4 NAV1 RACGAP1 DNAI4 KIF4B ATP2B4 PHLDB2 PCNT

4.73e-05105814420GO:0007017
GeneOntologyBiologicalProcessmitotic spindle midzone assembly

KIF4A RACGAP1 KIF4B

5.28e-05111443GO:0051256
GeneOntologyBiologicalProcessmitotic spindle elongation

KIF4A RACGAP1 KIF4B

7.00e-05121443GO:0000022
GeneOntologyBiologicalProcessspindle midzone assembly

KIF4A RACGAP1 KIF4B

1.15e-04141443GO:0051255
GeneOntologyBiologicalProcessspindle elongation

KIF4A RACGAP1 KIF4B

1.15e-04141443GO:0051231
GeneOntologyCellularComponenttransferase complex

DCAF6 ACACB RNF19A RNF19B FBXL4 KANSL3 MED24 KMT2C BRCA1 PIK3C2B PARD6A CDK13 MSL3 ANKIB1 DEPDC5 WDFY3 KAT6B MED13 USP47 MGRN1

1.26e-0596314620GO:1990234
GeneOntologyCellularComponentintracellular protein-containing complex

DCAF6 AIMP2 RNF19A RNF19B FBXL4 KANSL3 CEP170 MED24 BORCS5 BRCA1 MSL3 ANKIB1 TRAPPC10 RACGAP1 DEPDC5 KAT6B USP47 MGRN1

1.53e-0497214618GO:0140535
GeneOntologyCellularComponentubiquitin ligase complex

DCAF6 RNF19A RNF19B FBXL4 MED24 BRCA1 ANKIB1 DEPDC5 USP47 MGRN1

1.88e-0435214610GO:0000151
GeneOntologyCellularComponentdendritic spine membrane

SLC9A5 ATP6AP2 DAGLA

2.52e-04181463GO:0032591
HumanPhenoHypospadias

FRAS1 PEX6 NSUN2 GATAD2B RFWD3 FBXL4 FANCD2 FREM2 BRCA1 CDCA7 ATP6AP2 KAT6B PCNT

2.25e-053774713HP:0000047
HumanPhenoDisplacement of the urethral meatus

FRAS1 PEX6 NSUN2 GATAD2B RFWD3 FBXL4 FANCD2 FREM2 BRCA1 CDCA7 ATP6AP2 KAT6B PCNT

3.90e-053974713HP:0100627
HumanPhenoAbnormal male urethral meatus morphology

FRAS1 PEX6 NSUN2 GATAD2B RFWD3 FBXL4 FANCD2 FREM2 BRCA1 CDCA7 ATP6AP2 KAT6B PCNT

4.12e-053994713HP:0032076
HumanPhenoAbnormal size of the palpebral fissures

RBM10 NSUN2 GATAD2B RFWD3 FANCD2 BRCA1 CDK13 KAT6B MED13 ADAMTSL2 PCNT

5.97e-052984711HP:0200007
HumanPhenoHypertelorism

FRAS1 LEMD3 RBL2 RBM10 PEX6 NSUN2 NSRP1 GATAD2B RFWD3 FANCD2 FREM2 BRCA1 CDCA7 CDK13 DEPDC5 PLCB3 MBD5 KAT6B MED13

6.37e-058304719HP:0000316
HumanPhenoThick eyebrow

LEMD3 RBM10 NSUN2 FBXL4 KMT2C CDK13 DEPDC5 MBD5

6.71e-05154478HP:0000574
HumanPhenoBicornuate uterus

FRAS1 RFWD3 FANCD2 FREM2 BRCA1

1.01e-0452475HP:0000813
HumanPhenoTracheal stenosis

FRAS1 FREM2 ADAMTSL2 PCNT

1.28e-0429474HP:0002777
HumanPhenoAbnormal tracheal morphology

FRAS1 RFWD3 FANCD2 KMT2C FREM2 BRCA1 ADAMTSL2 PCNT

1.35e-04170478HP:0002778
HumanPhenoMeckel diverticulum

RBM10 RFWD3 FANCD2 BRCA1

1.67e-0431474HP:0002245
HumanPhenoAbnormality of the urethra

FRAS1 PEX6 NSUN2 GATAD2B RFWD3 FBXL4 FANCD2 FREM2 BRCA1 CDCA7 ATP6AP2 KAT6B PCNT

2.00e-044654713HP:0000795
HumanPhenoAnal stenosis

FRAS1 NSUN2 FREM2 KAT6B

2.41e-0434474HP:0002025
HumanPhenoMalformed lacrimal duct

FRAS1 FREM2

2.49e-043472HP:0007993
HumanPhenoSloping forehead

RBM10 NSUN2 RFWD3 FANCD2 BRCA1 TRAPPC10 KAT6B PCNT

2.71e-04188478HP:0000340
HumanPhenoAnal atresia

FRAS1 RFWD3 FANCD2 KMT2C FREM2 BRCA1 KAT6B

2.91e-04143477HP:0002023
DomainPKD/REJ-like

PKD1L1 PKD1L2 KIAA0319

9.01e-0661453IPR002859
DomainREJ

PKD1L1 PKD1L2 KIAA0319

9.01e-0661453PF02010
DomainE3_UB_ligase_RBR

RNF19A RNF19B ANKIB1

5.28e-05101453IPR031127
DomainARHGEF5_35

ARHGEF5 ARHGEF35

5.99e-0521452PF15441
DomainARHGEF5/35_N

ARHGEF5 ARHGEF35

5.99e-0521452IPR029212
DomainMBD

MBD6 SETDB1 MBD5

7.23e-05111453SM00391
DomainMBD

MBD6 SETDB1 MBD5

7.23e-05111453PS50982
DomainMethyl_CpG_DNA-bd

MBD6 SETDB1 MBD5

7.23e-05111453IPR001739
DomainMBD

MBD6 SETDB1 MBD5

7.23e-05111453PF01429
DomainDNA-bd_dom

MBD6 SETDB1 MBD5

7.23e-05111453IPR016177
DomainIBR

RNF19A RNF19B ANKIB1

1.57e-04141453PF01485
DomainIBR

RNF19A RNF19B ANKIB1

1.57e-04141453SM00647
DomainIBR_dom

RNF19A RNF19B ANKIB1

1.95e-04151453IPR002867
DomainLH2

PKD1L1 PKD1L2 ALOX15B

3.43e-04181453SM00308
DomainREJ

PKD1L1 PKD1L2

3.56e-0441452PS51111
DomainREJ_dom

PKD1L1 PKD1L2

3.56e-0441452IPR014010
Domain-

PKD1L1 PKD1L2 ALOX15B

5.50e-042114532.60.60.20
DomainPLAT

PKD1L1 PKD1L2 ALOX15B

5.50e-04211453PF01477
DomainPLAT/LH2_dom

PKD1L1 PKD1L2 ALOX15B

5.50e-04211453IPR001024
DomainPLAT

PKD1L1 PKD1L2 ALOX15B

5.50e-04211453PS50095
DomainLEM

LEMD3 TMPO

5.89e-0451452SM00540
Domain-

RNF19A RNF19B MYRIP MARCHF7 RFWD3 KMT2C BRCA1 ANKIB1 WDFY3 KAT6B MGRN1

7.74e-04449145113.30.40.10
DomainRudment_hybrid_motif

ACACB GART

8.80e-0461452IPR011054
DomainZnf_RING/FYVE/PHD

RNF19A RNF19B MYRIP MARCHF7 RFWD3 KMT2C BRCA1 ANKIB1 WDFY3 KAT6B MGRN1

9.25e-0445914511IPR013083
DomainZnf_FYVE_PHD

TCF20 MYRIP KMT2C ANKIB1 WDFY3 KAT6B

1.02e-031471456IPR011011
DomainLEM/LEM-like_dom

LEMD3 TMPO

1.23e-0371452IPR011015
DomainLEM_dom

LEMD3 TMPO

1.23e-0371452IPR003887
DomainSyndecan

NRXN3 NRXN2

1.23e-0371452PF01034
DomainLEM

LEMD3 TMPO

1.23e-0371452PF03020
DomainLEM

LEMD3 TMPO

1.23e-0371452PS50954
DomainSyndecan/Neurexin_dom

NRXN3 NRXN2

1.23e-0371452IPR027789
Domain-

LEMD3 TMPO

1.23e-03714521.10.720.40
DomainCalx_beta

FRAS1 FREM2

1.63e-0381452SM00237
DomainATP_grasp_subdomain_2

ACACB GART TTLL4

1.76e-03311453IPR013816
DomainPH_dom-like

DOK6 ARHGEF5 DOCK9 ARHGAP9 DGKD PTPN4 PLCB3 WDFY3 PHLDB2 ANKS1A

1.84e-0342614510IPR011993
DomainCalx_beta

FRAS1 FREM2

2.08e-0391452IPR003644
DomainPKD/Chitinase_dom

PKD1L1 KIAA0319

2.08e-0391452IPR022409
DomainPKD

PKD1L1 KIAA0319

2.08e-0391452SM00089
DomainCalx-beta

FRAS1 FREM2

2.08e-0391452PF03160
DomainAAA

VWA8 PEX6 ATAD2B

2.30e-03341453PS00674
DomainPTPc

PTPN4 PTPRJ PTPRZ1

2.71e-03361453SM00194
DomainBROMODOMAIN_1

ATAD2B BRD9 BRWD1

2.94e-03371453PS00633
DomainPKD

PKD1L1 KIAA0319

3.14e-03111452PS50093
DomainPKD_dom

PKD1L1 KIAA0319

3.14e-03111452IPR000601
DomainPKD_channel

PKD1L1 PKD1L2

3.14e-03111452PF08016
DomainPKD1_2_channel

PKD1L1 PKD1L2

3.14e-03111452IPR013122
Domain-

PKD1L1 KIAA0319

3.14e-031114522.60.40.670
DomainBromodomain

ATAD2B BRD9 BRWD1

3.17e-03381453PF00439
DomainTYR_PHOSPHATASE_PTP

PTPN4 PTPRJ PTPRZ1

3.41e-03391453PS50055
Domain-

DOK6 ARHGEF5 DOCK9 ARHGAP9 DGKD PTPN4 PLCB3 PHLDB2 ANKS1A

3.51e-0339114592.30.29.30
DomainPTPase_domain

PTPN4 PTPRJ PTPRZ1

3.94e-03411453IPR000242
DomainY_phosphatase

PTPN4 PTPRJ PTPRZ1

3.94e-03411453PF00102
DomainBROMODOMAIN_2

ATAD2B BRD9 BRWD1

3.94e-03411453PS50014
DomainZnf_RING

RNF19A RNF19B MARCHF7 RFWD3 KMT2C BRCA1 ANKIB1 MGRN1

3.99e-033261458IPR001841
DomainWD40

DCAF6 EML4 RFWD3 TBC1D31 DNAI4 WDFY3 BRWD1

4.15e-032591457PF00400
DomainBromodomain

ATAD2B BRD9 BRWD1

4.22e-03421453IPR001487
DomainBROMO

ATAD2B BRD9 BRWD1

4.22e-03421453SM00297
Domain-

ATAD2B BRD9 BRWD1

4.22e-034214531.20.920.10
Domain-

ACACB GART

4.41e-031314523.40.50.20
DomainWD40

DCAF6 EML4 RFWD3 TBC1D31 DNAI4 WDFY3 BRWD1

4.99e-032681457SM00320
DomainATP_GRASP

ACACB GART

5.12e-03141452PS50975
DomainSEA

MUC16 IMPG2

5.12e-03141452SM00200
DomainATP-grasp

ACACB GART

5.12e-03141452IPR011761
DomainPreATP-grasp_dom

ACACB GART

5.12e-03141452IPR016185
DomainNeurexin-like

NRXN3 NRXN2

5.12e-03141452IPR003585
Domain4.1m

NRXN3 NRXN2

5.12e-03141452SM00294
DomainWD40_repeat

DCAF6 EML4 RFWD3 TBC1D31 DNAI4 WDFY3 BRWD1

5.41e-032721457IPR001680
DomainSET

PRDM7 KMT2C SETDB1

5.45e-03461453SM00317
Domain-

MUC16 IMPG2

5.88e-031514523.30.70.960
Domain-

ACACB GART

5.88e-031514523.30.1490.20
DomainWD_REPEATS_1

DCAF6 EML4 RFWD3 TBC1D31 DNAI4 WDFY3 BRWD1

6.07e-032781457PS00678
DomainWD_REPEATS_2

DCAF6 EML4 RFWD3 TBC1D31 DNAI4 WDFY3 BRWD1

6.19e-032791457PS50082
DomainWD_REPEATS_REGION

DCAF6 EML4 RFWD3 TBC1D31 DNAI4 WDFY3 BRWD1

6.19e-032791457PS50294
DomainPost-SET_dom

KMT2C SETDB1

6.69e-03161452IPR003616
DomainPostSET

KMT2C SETDB1

6.69e-03161452SM00508
DomainPOST_SET

KMT2C SETDB1

6.69e-03161452PS50868
DomainSET_dom

PRDM7 KMT2C SETDB1

6.88e-03501453IPR001214
DomainSET

PRDM7 KMT2C SETDB1

6.88e-03501453PS50280
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

RAD52 DCAF6 AIMP2 SHB MYRIP PARD3B CLASP2 FRYL FOXJ3 NSRP1 KANSL3 CEP170 KMT2C PTPN4 PTPRJ MBNL2 CDK13 NT5C2 ANKIB1 NAV1 TNFRSF19 ABLIM2 MBD5 KAT6B SAP130 DAGLA IL6R CDH15 PCNT ANKS1A MGRN1

1.72e-1314891483128611215
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

LIMA1 TCF20 GIT1 EML4 RBM10 ZNF507 NSUN2 GATAD2B FANCD2 KANSL3 MED24 CDK13 MSL3 TRAPPC10 TMPO PLCB3 KAT6B MED13 PHLDB2 USP47 ANKS1A

1.77e-117741482115302935
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

STK36 FRAS1 VWA8 DOCK9 LAD1 PEX6 CLASP2 FRYL MBD6 ELAC2 KANSL3 KMT2C EIF4ENIF1 PER2 PIK3C2B CDK13 TTLL4 NAV1 CENPV DEPDC5 WDFY3 MBD5 MED13 PCNT

5.63e-1111051482435748872
Pubmed

Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.

STK36 VWA8 SORBS1 FOXJ3 KIAA0319 SETDB1 NRXN2 NAV1 MBD5 MED13

2.47e-101301481012421765
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

VWA8 ZNF507 FOXJ3 KANSL3 KMT2C NRXN3 NRXN2 TTLL4 ANKIB1 RACGAP1 DEPDC5 KAT6B DAGLA MED13 ANKS1A MGRN1

1.13e-095291481614621295
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

LIMA1 TCF20 GIT1 KIF4A CLASP2 SORBS1 GATAD2B KIAA0319 CEP170 CAMKV NUFIP2 NT5C2 NAV1 RACGAP1 KIF4B WDFY3 ATP2B4 PHLDB2 PCNT ANKS1A

5.57e-099631482028671696
Pubmed

Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.

GIT1 LEMD3 KIF4A ELAC2 CEP350 CEP170 MED24 TBC1D31 BRCA1 NUFIP2 MSL3 NAV1 RACGAP1 CENPV MED13 PCNT

1.85e-086451481625281560
Pubmed

The human cytoplasmic dynein interactome reveals novel activators of motility.

TTF2 ACACB GIT1 STXBP4 GOSR1 PKD1L1 SHB ZNF507 PARD3B SORBS1 CEP350 BORCS5 TBC1D31 EIF4ENIF1 USP47 PCNT ANKS1A BRWD1

2.70e-088531481828718761
Pubmed

Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.

TTF2 LIMA1 ACACB STXBP4 CLASP2 FRYL SORBS1 CEP170 EIF4ENIF1 TRAPPC10 NAV1 PHLDB2 ANKS1A

6.79e-084461481324255178
Pubmed

Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette.

LIMA1 RBM10 DGKD FRYL SORBS1 FOXJ3 NSRP1 PTPN4 MBNL2 TTLL4 WDFY3 MBD5 KAT6B MED13

8.04e-085361481415840001
Pubmed

Exchangeable gene trap using the Cre/mutated lox system.

LIMA1 RBM10 DGKD FRYL SORBS1 FOXJ3 NSRP1 PTPN4 MBNL2 TTLL4 WDFY3 MBD5 KAT6B MED13

8.42e-085381481410512203
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

TCF20 LEMD3 GOSR1 KIF4A CLASP2 GATAD2B CEP350 CEP170 SETDB1 TBC1D31 EIF4ENIF1 TTLL4 NUFIP2 NAV1 RACGAP1 ANKS1A

1.07e-077331481634672954
Pubmed

Phosphoproteomic analysis of the developing mouse brain.

CLASP2 NSUN2 GATAD2B EIF4ENIF1 CAMKV CDCA7 PARD6A NUFIP2 USP47 ANKS1A

1.13e-072461481015345747
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

LIMA1 TCF20 GIT1 ARHGEF5 STXBP4 PARD3B CLASP2 FRYL SORBS1 CEP350 CEP170 BORCS5 PIK3C2B NAV1 RACGAP1 PHLDB2 ANKS1A

1.73e-078611481736931259
Pubmed

The expanding role of MBD genes in autism: identification of a MECP2 duplication and novel alterations in MBD5, MBD6, and SETDB1.

MBD6 SETDB1 MBD5

3.01e-074148323055267
Pubmed

Comprehensive identification of phosphorylation sites in postsynaptic density preparations.

LEMD3 CLASP2 SORBS1 PTPRZ1 PRICKLE2 TMPO ABLIM2 DAGLA BRWD1

7.09e-07231148916452087
Pubmed

Prickle1 promotes focal adhesion disassembly in cooperation with the CLASP-LL5β complex in migrating cells.

CLASP2 PRICKLE2 PHLDB2

7.50e-075148327378169
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

FRAS1 C12orf56 EML4 ARHGEF5 PEX6 COLGALT1 NSUN2 RFWD3 FREM2 CDK13 ANKIB1 RACGAP1 PLCB3 MGRN1

8.16e-076501481438777146
Pubmed

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.

TTF2 AIMP2 TCF20 RBM10 ZNF507 KIF4A FOXJ3 NSUN2 GATAD2B KANSL3 CEP170 MED24 KMT2C BRCA1 CDK13 BRD9 TMPO SAP130

1.17e-0611031481834189442
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

DCAF6 ZBTB2 VWA8 PEX6 NSRP1 GATAD2B FANCD2 CEP170 SETDB1 EIF4ENIF1 BRCA1 BRD9 WDFY3 KAT6B SAP130 CDH15 PHLDB2 BRWD1

1.38e-0611161481831753913
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

FRAS1 TCF20 RBM10 DOCK9 SORBS1 KIAA0319 SETDB1 PER2 NUFIP2 NAV1 PCNT

1.50e-064071481112693553
Pubmed

Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization.

LIMA1 GIT1 PARD3B FRYL CEP170 NUFIP2 RACGAP1 PHLDB2 ANKS1A

1.61e-06255148915324660
Pubmed

Age of onset of amyotrophic lateral sclerosis is modulated by a locus on 1p34.1.

STK36 NRXN3 TTLL4 CENPV

1.78e-0621148422959728
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

TCF20 LEMD3 EML4 RBM10 KIF4A NSRP1 GATAD2B CEP170 BRCA1 MBNL2 ATAD2B NUFIP2 BRD9 RACGAP1 TMPO SAP130

3.38e-069541481636373674
Pubmed

Targeted proteomic analysis of 14-3-3 sigma, a p53 effector commonly silenced in cancer.

ARHGEF5 LAD1 PARD3B PIK3C2B RACGAP1 ANKS1A

5.16e-06102148615778465
Pubmed

Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

FRAS1 ZBTB2 DPP10 KMT2C RACGAP1 MBD5

5.46e-06103148610819331
Pubmed

SNX27-driven membrane localisation of OTULIN antagonises linear ubiquitination and NF-κB signalling activation.

DCAF6 GIT1 VWA8 LEMD3 RBM10 NT5C2 CENPV PLCB3 ATP2B4 ANKS1A

5.51e-063781481034315543
Pubmed

Human Immunodeficiency Virus Type 1 Vpr Mediates Degradation of APC1, a Scaffolding Component of the Anaphase-Promoting Complex/Cyclosome.

TCF20 ACACB LEMD3 CEP350 CEP170 MED24 EIF4ENIF1 RACGAP1

9.98e-06242148834011540
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

TTF2 AIMP2 TCF20 LEMD3 RBM10 GOSR1 KIF4A GATAD2B RFWD3 KANSL3 KMT2C BRCA1 CDK13 MSL3 RACGAP1 TMPO CENPV SAP130

1.06e-0512941481830804502
Pubmed

Defining the membrane proteome of NK cells.

AIMP2 GIT1 EML4 DOCK9 GOSR1 KIF4A TTPAL CLASP2 COLGALT1 CEP350 EIF4ENIF1 NUFIP2 TMPO ATP2B4 MED13 PCNT MGRN1

1.06e-0511681481719946888
Pubmed

Human transcription factor protein interaction networks.

LIMA1 TCF20 ACACB RBM10 ZNF507 MBD6 NSUN2 GATAD2B ZNF284 KANSL3 MED24 KMT2C SETDB1 EIF4ENIF1 BRCA1 BRD9 NT5C2 RACGAP1 SAP130

1.12e-0514291481935140242
Pubmed

The in vivo Interaction Landscape of Histones H3.1 and H3.3.

TCF20 ARHGEF5 KIF4A FOXJ3 GATAD2B BRCA1 ATAD2B BRD9 RACGAP1 TMPO CENPV BRWD1

1.23e-056081481236089195
Pubmed

An inducible CRISPR/Cas9 screen identifies DTX2 as a transcriptional regulator of human telomerase.

ZBTB2 TCF20 ACACB LEMD3 RBM10 SHB ATP2B4

1.28e-05180148735198878
Pubmed

Polycystin-1L2 is a novel G-protein-binding protein.

PKD1L1 PKD1L2

1.80e-052148215203210
Pubmed

Atp6ap2/(pro)renin receptor interacts with Par3 as a cell polarity determinant required for laminar formation during retinal development in mice.

PARD3B ATP6AP2

1.80e-052148224305829
Pubmed

KIF4 regulates neuronal morphology and seizure susceptibility via the PARP1 signaling pathway.

KIF4A KIF4B

1.80e-052148236482480
Pubmed

Identification of two novel CAKUT-causing genes by massively parallel exon resequencing of candidate genes in patients with unilateral renal agenesis.

FRAS1 FREM2

1.80e-052148221900877
Pubmed

The multiple functions of kinesin-4 family motor protein KIF4 and its clinical potential.

KIF4A KIF4B

1.80e-052148230081192
Pubmed

Chromokinesin Kif4 promotes proper anaphase in mouse oocyte meiosis.

KIF4A KIF4B

1.80e-052148231067151
Pubmed

Cellular motor protein KIF-4 associates with retroviral Gag.

KIF4A KIF4B

1.80e-052148210559369
Pubmed

KIF4 regulates midzone length during cytokinesis.

KIF4A KIF4B

1.80e-052148221565503
Pubmed

Molecular study of 33 families with Fraser syndrome new data and mutation review.

FRAS1 FREM2

1.80e-052148218671281
Pubmed

A novel microtubule-based motor protein (KIF4) for organelle transports, whose expression is regulated developmentally.

KIF4A KIF4B

1.80e-05214827929562
Pubmed

Loss of expression of FANCD2 protein in sporadic and hereditary breast cancer.

FANCD2 BRCA1

1.80e-052148217333336
Pubmed

Novel loss of function variants in FRAS1 AND FREM2 underlie renal agenesis in consanguineous families.

FRAS1 FREM2

1.80e-052148232643034
Pubmed

Whole genome expression microarray reveals novel roles for Kif4 in monocyte/macrophage cells.

KIF4A KIF4B

1.80e-052148231486502
Pubmed

Identification of novel loci for bipolar I disorder in a multi-stage genome-wide association study.

NRXN3 KAT6B

1.80e-052148224444492
Pubmed

Assignment of the kinesin family member 4 genes (KIF4A and KIF4B) to human chromosome bands Xq13.1 and 5q33.1 by in situ hybridization.

KIF4A KIF4B

1.80e-052148210773663
Pubmed

Identification of GIT1/Cat-1 as a substrate molecule of protein tyrosine phosphatase zeta /beta by the yeast substrate-trapping system.

GIT1 PTPRZ1

1.80e-052148211381105
Pubmed

Dynamic regulation of pol II transcription by the mammalian Mediator complex.

MED24 MED13

1.80e-052148215896744
Pubmed

MBD5 and MBD6 interact with the human PR-DUB complex through their methyl-CpG-binding domain.

MBD6 MBD5

1.80e-052148224634419
Pubmed

Missense Pathogenic variants in KIF4A Affect Dental Morphogenesis Resulting in X-linked Taurodontism, Microdontia and Dens-Invaginatus.

KIF4A KIF4B

1.80e-052148231616463
Pubmed

Kif4 regulates the expression of VEGFR1 through the PI3K/Akt signaling pathway in RAW264.7 monocytes/macrophages.

KIF4A KIF4B

1.80e-052148228350061
Pubmed

The human proteins MBD5 and MBD6 associate with heterochromatin but they do not bind methylated DNA.

MBD6 MBD5

1.80e-052148220700456
Pubmed

Mediator--a universal complex in transcriptional regulation.

MED24 MED13

1.80e-052148211454195
Pubmed

Kif4 interacts with EB1 and stabilizes microtubules downstream of Rho-mDia in migrating fibroblasts.

KIF4A KIF4B

1.80e-052148224658398
Pubmed

Interaction of the Fanconi anemia proteins and BRCA1 in a common pathway.

FANCD2 BRCA1

1.80e-052148211239454
Pubmed

Structural basis for the ATP-induced isomerization of kinesin.

KIF4A KIF4B

1.80e-052148223500491
Pubmed

Comparative study of methyl-CpG-binding domain proteins.

MBD6 MBD5

1.80e-052148212529184
Pubmed

Binding of murine leukemia virus Gag polyproteins to KIF4, a microtubule-based motor protein.

KIF4A KIF4B

1.80e-05214829658142
Pubmed

Alcohol metabolism in human cells causes DNA damage and activates the Fanconi anemia-breast cancer susceptibility (FA-BRCA) DNA damage response network.

FANCD2 BRCA1

1.80e-052148221919919
Pubmed

FOXN2, identified as a novel biomarker in serum, modulates the transforming growth factor-beta signaling pathway through its interaction with partitioning defective 6 homolog alpha, contributing to the pathogenesis of gastric cancer.

FOXN2 PARD6A

1.80e-052148238954805
Pubmed

Overlapping Activities of Two Neuronal Splicing Factors Switch the GABA Effect from Excitatory to Inhibitory by Regulating REST.

DOCK9 CLASP2 SORBS1 NRXN3 MBNL2 TMPO

1.90e-05128148630995482
Pubmed

Compartmentalization of the SUMO/RNF4 pathway by SLX4 drives DNA repair.

AIMP2 ACACB RBM10 GART KIF4A GATAD2B CEP350 BRCA1 NUFIP2

2.40e-05357148937059091
Pubmed

A CRISPR-based screen for Hedgehog signaling provides insights into ciliary function and ciliopathies.

STK36 GIT1 ARHGEF5 LAD1 SHB KIF4A KIF4B PCNT

3.15e-05284148829459677
Pubmed

Systematic analysis of human protein complexes identifies chromosome segregation proteins.

DCAF6 LEMD3 STXBP4 KIF4A CLASP2 NSUN2 CEP350 KANSL3 CEP170 PER2 PARD6A MSL3 RACGAP1 TMPO KIF4B USP47

3.56e-0511551481620360068
Pubmed

hPrimpol1/CCDC111 is a human DNA primase-polymerase required for the maintenance of genome integrity.

RAD52 RFWD3 HELB

4.06e-0516148324126761
Pubmed

The p300/YY1/miR-500a-5p/HDAC2 signalling axis regulates cell proliferation in human colorectal cancer.

LIMA1 GIT1 NSUN2 ELAC2 GATAD2B NUFIP2 RACGAP1 TMPO

4.42e-05298148830737378
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

TTF2 LIMA1 ACACB RBM10 STXBP4 GART KIF4A NSUN2 NSRP1 CEP170 NUFIP2 TMPO PCNT ANKS1A

4.87e-059341481433916271
Pubmed

Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.

LEMD3 RNF19A EML4 GOSR1 PEX6 CLASP2 RETREG3 KIAA0319 FANCD2 MED24 PTPRJ ANKIB1 WDFY3 ATP2B4 MGRN1

5.03e-0510611481533845483
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

DOCK9 KMT2C NRXN2 WDFY3 KAT6B DAGLA PCNT

5.33e-05225148712168954
Pubmed

The variant Polycomb Repressor Complex 1 component PCGF1 interacts with a pluripotency sub-network that includes DPPA4, a regulator of embryogenesis.

RAD52 ZBTB2 TCF20 ACACB LEMD3 MUC16 COLGALT1 FANCD2 SAP130

5.35e-05396148926687479
Pubmed

Conditional Knockout of Neurexins Alters the Contribution of Calcium Channel Subtypes to Presynaptic Ca2+ Influx.

NRXN3 NRXN2

5.38e-053148238891114
Pubmed

BRCA1/FANCD2/BRG1-Driven DNA Repair Stabilizes the Differentiation State of Human Mammary Epithelial Cells.

FANCD2 BRCA1

5.38e-053148227373334
Pubmed

CLASP2-dependent microtubule capture at the neuromuscular junction membrane requires LL5β and actin for focal delivery of acetylcholine receptor vesicles.

CLASP2 PHLDB2

5.38e-053148225589673
Pubmed

BRCA1 and RNAi factors promote repair mediated by small RNAs and PALB2-RAD52.

RAD52 BRCA1

5.38e-053148233536619
Pubmed

Tumor formation via loss of a molecular motor protein.

KIF4A KIF4B

5.38e-053148216890532
Pubmed

RNF19A-mediated ubiquitination of BARD1 prevents BRCA1/BARD1-dependent homologous recombination.

RNF19A BRCA1

5.38e-053148234789768
Pubmed

alpha-Neurexins are required for efficient transmitter release and synaptic homeostasis at the mouse neuromuscular junction.

NRXN3 NRXN2

5.38e-053148216406382
Pubmed

KIF4 mediates anterograde translocation and positioning of ribosomal constituents to axons.

KIF4A KIF4B

5.38e-053148219158085
Pubmed

Alternative Splicing of Presynaptic Neurexins Differentially Controls Postsynaptic NMDA and AMPA Receptor Responses.

NRXN3 NRXN2

5.38e-053148231005376
Pubmed

Identification of the human homologue of mouse KIF4, a kinesin superfamily motor protein.

KIF4A KIF4B

5.38e-053148210978527
Pubmed

Regulated Dynamic Trafficking of Neurexins Inside and Outside of Synaptic Terminals.

NRXN3 NRXN2

5.38e-053148226446217
Pubmed

Utility of DNA repair protein foci for the detection of putative BRCA1 pathway defects in breast cancer biopsies.

FANCD2 BRCA1

5.38e-053148219671671
Pubmed

Analysis of the human neurexin genes: alternative splicing and the generation of protein diversity.

NRXN3 NRXN2

5.38e-053148211944992
Pubmed

Alternative splicing of neurexins 1-3 is modulated by neuroinflammation in the prefrontal cortex of a murine model of multiple sclerosis.

NRXN3 NRXN2

5.38e-053148233058888
Pubmed

Important contribution of alpha-neurexins to Ca2+-triggered exocytosis of secretory granules.

NRXN3 NRXN2

5.38e-053148217035546
Pubmed

Neurexins: three genes and 1001 products.

NRXN3 NRXN2

5.38e-05314829448462
Pubmed

Deletion of α-neurexin II results in autism-related behaviors in mice.

NRXN3 NRXN2

5.38e-053148225423136
Pubmed

BRCA1-independent ubiquitination of FANCD2.

FANCD2 BRCA1

5.38e-053148212887909
Pubmed

Direct recording and molecular identification of the calcium channel of primary cilia.

PKD1L1 PKD1L2

5.38e-053148224336289
Pubmed

Endogenous β-neurexins on axons and within synapses show regulated dynamic behavior.

NRXN3 NRXN2

5.38e-053148234133920
Pubmed

The within-subject application of diffusion tensor MRI and CLARITY reveals brain structural changes in Nrxn2 deletion mice.

NRXN3 NRXN2

5.38e-053148230858964
Pubmed

CLASPs attach microtubule plus ends to the cell cortex through a complex with LL5beta.

CLASP2 PHLDB2

5.38e-053148216824950
Pubmed

Neurexins 1-3 Each Have a Distinct Pattern of Expression in the Early Developing Human Cerebral Cortex.

NRXN3 NRXN2

5.38e-053148228013231
Pubmed

Ketamine Restores Thalamic-Prefrontal Cortex Functional Connectivity in a Mouse Model of Neurodevelopmental Disorder-Associated 2p16.3 Deletion.

NRXN3 NRXN2

5.38e-053148231812984
Pubmed

Structure and evolution of neurexin genes: insight into the mechanism of alternative splicing.

NRXN3 NRXN2

5.38e-053148212036300
Pubmed

β-Neurexins Control Neural Circuits by Regulating Synaptic Endocannabinoid Signaling.

NRXN3 NRXN2

5.38e-053148226213384
Pubmed

Neurexin gene family variants as risk factors for autism spectrum disorder.

NRXN3 NRXN2

5.38e-053148229045040
Pubmed

Structural and functional characterization of the IgSF21-neurexin2α complex and its related signaling pathways in the regulation of inhibitory synapse organization.

NRXN3 NRXN2

5.38e-053148238571813
InteractionYWHAE interactions

RAD52 LIMA1 AIMP2 GIT1 ARHGEF5 RBM10 DOCK9 PARD3B CLASP2 FRYL SORBS1 MBD6 FANCD2 CEP170 PTPN4 BORCS5 BRCA1 PER2 PIK3C2B CDK13 NT5C2 NAV1 RACGAP1 TMPO DEPDC5 SAP130 ATP2B4 PHLDB2 ANKS1A

1.93e-08125614529int:YWHAE
InteractionYWHAZ interactions

RAD52 LIMA1 AIMP2 GIT1 ARHGEF5 DOCK9 PARD3B CLASP2 FRYL SORBS1 FANCD2 CEP170 PTPN4 BORCS5 BRCA1 PER2 CAMKV CDCA7 PIK3C2B PARD6A NAV1 RACGAP1 DEPDC5 WDFY3 PHLDB2 USP47 PCNT ANKS1A

2.05e-07131914528int:YWHAZ
InteractionSFN interactions

LIMA1 ARHGEF5 STXBP4 LAD1 PARD3B CLASP2 FRYL SORBS1 CEP350 FANCD2 CEP170 CDCA7 PIK3C2B NAV1 RACGAP1 SAP130 PHLDB2 USP47 ANKS1A

5.75e-0769214519int:SFN
InteractionYWHAH interactions

LIMA1 TCF20 GIT1 ARHGEF5 STXBP4 DOCK9 PARD3B CLASP2 FRYL SORBS1 CEP350 FANCD2 CEP170 PTPN4 BORCS5 CDCA7 PIK3C2B PARD6A TRAPPC10 NAV1 RACGAP1 PHLDB2 PCNT ANKS1A

1.11e-06110214524int:YWHAH
InteractionTOP3B interactions

STK36 FRAS1 LIMA1 VWA8 DOCK9 LAD1 PEX6 CLASP2 FRYL MBD6 ELAC2 KANSL3 KMT2C EIF4ENIF1 PER2 PIK3C2B CDK13 ATP6AP2 TTLL4 NUFIP2 NAV1 RACGAP1 CENPV DEPDC5 WDFY3 MBD5 MED13 PCNT

1.79e-06147014528int:TOP3B
InteractionYWHAQ interactions

LIMA1 ZBTB2 AIMP2 ARHGEF5 PARD3B CLASP2 FRYL SORBS1 CEP350 FANCD2 CEP170 PTPN4 BORCS5 BRCA1 CDCA7 PIK3C2B NAV1 RACGAP1 TMPO PHLDB2 USP47 ANKS1A

1.63e-05111814522int:YWHAQ
InteractionYWHAG interactions

LIMA1 GIT1 ARHGEF5 STXBP4 DOCK9 SHB PARD3B CLASP2 FRYL SORBS1 CEP350 FANCD2 CEP170 PTPN4 BORCS5 CDCA7 PIK3C2B NUFIP2 TRAPPC10 NAV1 RACGAP1 PHLDB2 ANKS1A

2.90e-05124814523int:YWHAG
InteractionLGALS1 interactions

FRAS1 LIMA1 DCAF6 CDHR2 MUC16 FANCD2 FREM2 PTPRJ PTPRZ1 ATP6AP2 MGRN1

2.92e-0533214511int:LGALS1
InteractionYWHAB interactions

LIMA1 ARHGEF5 DOCK9 PARD3B CLASP2 FRYL SORBS1 CEP350 FANCD2 CEP170 PTPN4 BORCS5 PIK3C2B TRAPPC10 NAV1 RACGAP1 SAP130 PHLDB2 USP47 ANKS1A

3.99e-05101414520int:YWHAB
InteractionNANOG interactions

RAD52 ZBTB2 TCF20 ACACB LEMD3 MUC16 COLGALT1 NSUN2 GATAD2B KMT2C BRCA1 NUFIP2 SAP130

4.58e-0548114513int:NANOG
InteractionPRKY interactions

TTF2 STXBP4 ZNF507 PEX6 NAV1 CENPV ANKS1A

6.98e-051401457int:PRKY
InteractionFASN interactions

ZBTB2 AIMP2 CLASP2 C10orf90 COLGALT1 MBD6 NSUN2 FBXL4 FANCD2 KMT2C BRCA1 PER2 PIK3C2B CDK13 TMPO DEPDC5 MBD5 MED13 PCNT ANKS1A

7.57e-05106214520int:FASN
InteractionPOU5F1 interactions

TTF2 ZBTB2 TCF20 ACACB LEMD3 MUC16 KIF4A COLGALT1 GATAD2B FANCD2 SETDB1 TMPO SAP130 BRWD1

8.44e-0558414514int:POU5F1
InteractionFAM9C interactions

GOSR1 KIF4A CEP170 SETDB1 BORCS5

9.04e-05631455int:FAM9C
InteractionH3-3A interactions

TCF20 EML4 ARHGEF5 KIF4A FOXJ3 GATAD2B FANCD2 KMT2C BRCA1 ATAD2B BRD9 RACGAP1 TMPO CENPV SAP130 BRWD1

1.01e-0474914516int:H3-3A
GeneFamilyZinc fingers CXXC-type|Methyl-CpG binding domain containing

MBD6 SETDB1 MBD5

2.04e-05119231025
GeneFamilyWD repeat domain containing

DCAF6 EML4 RFWD3 TBC1D31 DNAI4 WDFY3 BRWD1

3.80e-04262927362
GeneFamilyLEM domain containing

LEMD3 TMPO

5.29e-0479221087
GeneFamilyRing finger proteins

RNF19A RNF19B MARCHF7 RFWD3 BRCA1 MGRN1

2.80e-0327592658
GeneFamilyLIM domain containing

LIMA1 PRICKLE2 ABLIM2

3.37e-03599231218
GeneFamilyWD repeat domain containing|DDB1 and CUL4 associated factors

DCAF6 BRWD1

3.72e-0318922498
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

DOK6 DOCK9 ARHGAP9 DGKD PHLDB2

4.04e-03206925682
GeneFamilyRing finger proteins|Fanconi anemia complementation groups|Protein phosphatase 1 regulatory subunits|BRCA1 A complex|BRCA1 B complex|BRCA1 C complex

FANCD2 BRCA1

4.58e-0320922548
GeneFamilyProtein tyrosine phosphatases, receptor type

PTPRJ PTPRZ1

5.05e-0321922813
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

DOCK9 SHB MARCHF7 CLASP2 FRYL FOXJ3 CEP350 CEP170 SETDB1 PTPN4 TBC1D31 BRCA1 CDK13 ATAD2B NT5C2 WDFY3 KAT6B ATP2B4 MED13 PCNT ANKS1A

1.62e-0885614821M4500
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN

SHB MARCHF7 CLASP2 FRYL FOXJ3 CEP350 CEP170 BRCA1 CDK13 ATAD2B KAT6B MED13 ANKS1A

2.60e-0646614813M13522
CoexpressionGSE27241_WT_VS_RORGT_KO_TH17_POLARIZED_CD4_TCELL_TREATED_WITH_DIGOXIN_UP

FRYL CEP350 KMT2C BRCA1 TTLL4 ATAD2B DEPDC5 MED13

8.80e-061801488M8239
CoexpressionBUSSLINGER_GASTRIC_IMMUNE_CELLS

FOXN2 RNF19A EML4 RBL2 DOCK9 MARCHF7 ARHGAP9 FRYL FOXJ3 GATAD2B CEP350 KMT2C PTPN4 PTPRJ CDK13 ATP6AP2 NUFIP2 TRAPPC10 KAT6B ATP2B4 MED13 USP47 BRWD1

1.09e-05149214823M40023
CoexpressionSCHAEFFER_PROSTATE_DEVELOPMENT_6HR_DN

FRAS1 LIMA1 TCF20 MARCHF7 FRYL RFWD3 KMT2C PTPRJ ATAD2B NUFIP2 NAV1 PHLDB2

1.46e-0546714812M1347
CoexpressionSCHAEFFER_PROSTATE_DEVELOPMENT_6HR_DN

FRAS1 LIMA1 TCF20 MARCHF7 FRYL RFWD3 KMT2C PTPRJ ATAD2B NUFIP2 NAV1 PHLDB2

2.07e-0548414812MM999
CoexpressionHE_LIM_SUN_FETAL_LUNG_C0_ACTC_POS_SMC_CELL

FRAS1 DPP10 DOCK9 TMTC2 RIOX1 SORBS1 ELAC2 FREM2 PIK3C2B PRICKLE2 PLCB3 PHLDB2 ANKS1A

3.13e-0558914813M45662
CoexpressionGSE27241_WT_VS_RORGT_KO_TH17_POLARIZED_CD4_TCELL_UP

TTF2 KIF4A RFWD3 FANCD2 BRCA1 RACGAP1 TMPO

4.05e-051631487M8235
CoexpressionDAZARD_RESPONSE_TO_UV_NHEK_DN

DOCK9 FRYL FOXJ3 CEP350 CEP170 PER2 ZNF264 WDFY3 KAT6B

5.46e-053001489M8702
CoexpressionAtlasFacebaseRNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_top-relative-expression-ranked_2500_k-means-cluster#4

DCAF6 VWA8 LEMD3 RBL2 RNF19B RAD9B TMTC2 CEP350 KMT2C NRXN3 NRXN2 PTPRZ1 NT5C2 TRAPPC10 CENPV DNAI4 KAT6B ADAMTSL2

2.39e-0672114618Facebase_RNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_2500_K4
CoexpressionAtlasFacebaseRNAseq_e8.5_Paraxial Mesoderm_top-relative-expression-ranked_2500_k-means-cluster#3

DCAF6 VWA8 LEMD3 RBL2 RNF19B RAD9B TMTC2 CEP350 KMT2C NRXN2 PTPRZ1 NT5C2 TRAPPC10 SERPING1 CENPV DNAI4 KAT6B ADAMTSL2

2.84e-0673014618Facebase_RNAseq_e8.5_Paraxial Mesoderm_2500_K3
ToppCellpdx|World / Sample and Cell Type and Tumor Cluster (all cells)

DOK6 FRAS1 TCF20 PARD3B DGKD NRXN3 BRCA1 PRICKLE2 HS3ST4 MED13

7.59e-1018614910de8e538c8767d41b8a52f5e58ba1affd4e7244c4
ToppCellpdx-Tumor_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

DOK6 FRAS1 TCF20 PARD3B DGKD NRXN3 BRCA1 PRICKLE2 HS3ST4 MED13

7.59e-10186149100b88a87158a9ca8de3bf40a4ff1687150707a5f0
ToppCellTCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6|TCGA-Prostate / Sample_Type by Project: Shred V9

FOXN2 LEMD3 GOSR1 FRYL ZXDA CEP350 TRAPPC10 WDFY3 MED13

1.90e-081931499abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCellpdx-Tumor_cells-T5|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

TCF20 DGKD FREM2 NRXN3 PTPRJ PRICKLE2 WDFY3 HS3ST4

2.31e-0718714987e376831a11ee72ed87abcdac631ca46ae29c250
ToppCellhuman_hepatoblastoma-Tumor_cells-T5|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

FRAS1 TCF20 DGKD FREM2 NRXN3 PRICKLE2 TNFRSF19 HS3ST4

2.41e-071881498b070a0667f1ee9b825b267b6c389b7c42fc436f9
ToppCellControl-Endothelial-Endothelial-FOXM1|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TTF2 KIF4A RFWD3 FANCD2 TBC1D31 BRCA1 RACGAP1 TMPO

2.51e-0718914981e1499b062d9c647c8f38b0c4e0d871d159be5dd
ToppCellCOVID-19-T_cells-Cycling_NK/T_cells|COVID-19 / group, cell type (main and fine annotations)

TTF2 KIF4A RFWD3 FANCD2 BRCA1 RACGAP1 TMPO PCNT

3.18e-071951498764ed100c28d9bc93ee5ecabc5291c8f184d78da
ToppCellTCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-5|TCGA-Ovary / Sample_Type by Project: Shred V9

STK36 DCAF6 FOXJ3 PTPN4 MBD5 IMPG2 ANKS1A

1.48e-06166149732d2eaf8a5d03881bf74d680825af2d5110b082d
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

DOK6 RNF19A EML4 DOCK9 ZNF507 PTPN4 ATP2B4

1.54e-06167149783969c36ac44b96afc9aa09400a99fa2b487f7ff
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

KIF4A RFWD3 KIAA0319 FANCD2 BRCA1 RACGAP1 TMPO

2.45e-06179149788d44b04eb5c079531db663ed98ddb20b60feb9a
ToppCelldroplet-Liver-LIVER_HEP-30m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGEF5 STXBP4 KANSL3 RUNDC3A SLC9A5 PIK3C2B NAV1

3.04e-061851497bdd2e6cb20294b39a9d856004bf57ba69cf877e2
ToppCellhuman_hepatoblastoma-Tumor_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

FRAS1 EML4 PARD3B TNFRSF19 HS3ST4 MBD5 MED13

3.89e-061921497916fbec1c7ab7969bda711886ac88e877e30c280
ToppCellhuman_hepatoblastoma|World / Sample and Cell Type and Tumor Cluster (all cells)

FRAS1 EML4 PARD3B TNFRSF19 HS3ST4 MBD5 MED13

4.02e-061931497e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCellsevere-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

FRAS1 RNF19A EML4 FRYL HELB KMT2C CDK13

4.60e-06197149757ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCellTracheal-NucSeq|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations

VWA8 PARD3B CLASP2 KMT2C PTPRJ WDFY3 MBD5

4.92e-06199149794b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCellmild|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

FRYL CEP350 KMT2C CDK13 ATAD2B NUFIP2 SERPING1

5.08e-06200149712f1685ce8f218433068e090c9d839cd5a1910bf
ToppCellCOVID-19-kidney-Technical/muscle_(EC)|kidney / Disease (COVID-19 only), tissue and cell type

DPP10 MUC16 C10orf90 NRXN3 HS3ST4 KIAA2012

7.45e-06139149664c35411bbe67acb5010dadc4b0b1be0f8b17737
ToppCell10x5'-bone_marrow-Lymphocytic_T_CD4-T_CD4/CD8|bone_marrow / Manually curated celltypes from each tissue

RNF19A EML4 DOCK9 HELB KMT2C KIF4B

1.44e-0515614961545169694f686d28648a68b552c2ae606599d66
ToppCellLPS-antiTNF-Endothelial-Endothelial-FOXM1|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TTF2 KIF4A FANCD2 TBC1D31 BRCA1 RACGAP1

1.85e-0516314965285318c52aa31c9b22dc2ffff078e32e408604d
ToppCell3'-GW_trimst-1.5-LargeIntestine-Neuronal-neuron_precursor|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CLASP2 RUNDC3A CAMKV PTPRZ1 TNFRSF19 CTRL

1.85e-05163149699cf60dc87f7ce288553091bffcd85109a02bd8f
ToppCell3'-GW_trimst-1.5-LargeIntestine-Neuronal-neuron_precursor-Neuroblast|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CLASP2 RUNDC3A CAMKV PTPRZ1 TNFRSF19 CTRL

1.85e-051631496510c0af66e82c5a8cf8edd0547dae4018a87dbbf
ToppCell3'-GW_trimst-2-LargeIntestine-Neuronal-Glial_immature-Glia_3_(BCAN+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

C10orf90 NRXN3 NRXN2 PTPRZ1 TNFRSF19 DAGLA

2.26e-0516914962456b3e7776e8a2214972be1b4d66a3ca5480ae0
ToppCelldroplet-Lung-21m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l48|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TTPAL GATAD2B PTPN4 CDCA7 SAP130 GASK1A

2.34e-051701496070d8683d1a5cc7d594ff0453c961a9bf982c2d0
ToppCell367C-Lymphocytic-NK_cells-Proliferating_NK_cell|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

GIT1 KIF4A RAD9B CRACDL RACGAP1 DNAI4

2.75e-0517514960b1aaa028ba844d4bcb4509fdab8bee648373935
ToppCell3'-GW_trimst-2-SmallIntestine-Neuronal-neuron_precursor-Neuroblast|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RUNDC3A CAMKV PTPRZ1 TNFRSF19 ABLIM2 CDH15

3.03e-05178149613dfd28a80889c2dacdc65b94a41bb9762dc409d
ToppCell3'-GW_trimst-2-SmallIntestine-Neuronal-neuron_precursor|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RUNDC3A CAMKV PTPRZ1 TNFRSF19 ABLIM2 CDH15

3.03e-051781496a9ba4089413b1c55d667ce836b6972ca572ee2b8
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_G2M|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KIF4A FANCD2 BRCA1 TTLL4 RACGAP1 TMPO

3.22e-0518014965e1680088065be14447d5d5465f91f7edd071a1e
ToppCellChildren_(3_yrs)-Epithelial-club_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

FRAS1 DPP10 C12orf56 GDF15 NRXN3 HS3ST4

3.22e-051801496b509c7d6bdfba672065fb722874bdc68de72ba1c
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-DN4_thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GIT1 SHB PEX6 MBD6 PTPRJ TTLL4

3.22e-051801496be10fe5bf7c3a671c42704ce7dd8226ab6896794
ToppCellLPS-IL1RA-Endothelial-Endothelial-FOXM1|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TTF2 KIF4A FANCD2 TBC1D31 BRCA1 RACGAP1

3.22e-051801496334e2b1f6eb7d4ece20b1c7b02107863f913237f
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-DN4_thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GIT1 SHB PEX6 MBD6 PTPRJ TTLL4

3.22e-0518014963b747a517ce75ef2ff09011c037dad7b01ed3e03
ToppCellP28-Endothelial-proliferative_endothelial_cell-proliferative_endothelial_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

KIF4A FANCD2 TBC1D31 BRCA1 RACGAP1 TMPO

3.33e-051811496e482fd116c00ff4d8db7be3c06b1bd1ffa2d479d
ToppCellP28-Endothelial-proliferative_endothelial_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

KIF4A FANCD2 TBC1D31 BRCA1 RACGAP1 TMPO

3.33e-0518114962be3d44619adb25d339e7a27b500a56e07e8de01
ToppCellfacs-Skin-Anagen-3m-Epithelial-Basal_IFE|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NSUN2 FCGBP PTPRZ1 TNFRSF19 IL6R PHLDB2

3.43e-05182149622d6f4790950508e8aa27e02a8133af5f53f13c8
ToppCell10x5'-Liver-Lymphocytic_T_CD4/8-lo-Cycling_T|Liver / Manually curated celltypes from each tissue

KIF4A BRCA1 CDCA7 RACGAP1 TMPO KIF4B

3.43e-05182149681557cdc88777f3bd4e1dd18a760b08fc29122ef
ToppCellControl-T_cells-Cycling_NK/T_cells|Control / group, cell type (main and fine annotations)

KIF4A FANCD2 BRCA1 CDCA7 RACGAP1 TMPO

3.76e-0518514969766216b41ee62bbac4caa25cb98ec5627a24075
ToppCellwk_15-18-Epithelial-Distal_epithelial_progenitor-epi-tip_intermediate|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

FRAS1 SHB C10orf90 ZXDA RETREG3 FREM2

3.76e-051851496636505a3d96f75d951ab42bcf8af6ae07abc732d
ToppCell3'-GW_trimst-1-LargeIntestine-Neuronal-neuron_precursor-Neuroblast|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CLASP2 RUNDC3A CAMKV PTPRZ1 CENPV TNFRSF19

3.99e-051871496dfc2b95d70daf533bc0cc4ce78af9f65dd75a25b
ToppCellControl-Endothelial_cells-Endothelial_cells_(general)|Control / group, cell type (main and fine annotations)

DOCK9 SORBS1 NRXN3 PRICKLE2 NAV1 ANKS1A

3.99e-051871496fb5bcbc8effdbf0e57fcb71aca990a4aa0d65ce8
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Epithelial-neuronal_stem_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF4A GDPD4 BRCA1 CDCA7 PTPRZ1 RACGAP1

3.99e-051871496a2076599b33ae6750961b573bfebcb9036fa4ee8
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Epithelial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF4A GDPD4 BRCA1 CDCA7 PTPRZ1 RACGAP1

3.99e-05187149638ee33295a21db4aae5ba085df033db9693e41c6
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Epithelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF4A GDPD4 BRCA1 CDCA7 PTPRZ1 RACGAP1

3.99e-051871496dbcec24d2c852964736c78e9d81650bff5c455ae
ToppCellrenal_medulla_nuclei|World / Celltypes from Cells and Nuclei per compartment and clinical group

ACACB TMTC2 PARD3B PTPN4 WDFY3 MBD5

4.23e-051891496830d9cd0dd706bce22eb2416f07b2c31c870a05a
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK9 KIF4A RFWD3 BRCA1 CDCA7 NAV1

4.36e-05190149631de1727822e9818652946dfb962daee77ffad68
ToppCellnormal_Pleural_Fluid-T/NK_cells-Undetermined|normal_Pleural_Fluid / Location, Cell class and cell subclass

KIF4A BRCA1 CDCA7 RACGAP1 TMPO KIF4B

4.36e-051901496165c61443ff0c8efbdad3b052bb00f46d81c5203
ToppCellpdx-Tumor_cells-T1|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

KIF4A RFWD3 FANCD2 BRCA1 RACGAP1 TMPO

4.36e-051901496d06ee5f89f1cec8db6897fe3b2a890a07cd3697b
ToppCell3'-GW_trimst-1-LargeIntestine-Neuronal-neuron_precursor|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CLASP2 RUNDC3A CAMKV PTPRZ1 CENPV TNFRSF19

4.49e-051911496a53616c84178eb6c29b48662358765b082df3f97
ToppCellControl-Myeloid-Macrophage_Alveolar|Myeloid / Disease state, Lineage and Cell class

LIMA1 ACACB VWA8 EML4 SERPING1 ANKS1A

4.49e-051911496a7bb8aba9c59c037d995a77928cc7b4d5cbb82b9
ToppCellfacs-Marrow-T-cells-3m-Lymphocytic-immature_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TTPAL DGKD PTPRJ PIK3C2B MED13 BRWD1

4.62e-0519214962de242d81dc085ae734eb7d1f091af9a542e0866
ToppCell10x5'-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8|lymph-node_spleen / Manually curated celltypes from each tissue

RNF19A EML4 DOCK9 CLASP2 HELB KMT2C

4.62e-05192149647646d7e4990be85072987f92bf18d52f8da752e
ToppCellfacs-Skin-Anagen-3m-Epithelial-basal_cell_of_epidermis|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NSUN2 FCGBP PTPRZ1 TMPO TNFRSF19 IL6R

4.62e-051921496ec1fd2fb6e71f87189d66261909a84e2be63cacb
ToppCellfacs-Marrow-T-cells-3m-Lymphocytic-immature_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TTPAL DGKD PTPRJ PIK3C2B MED13 BRWD1

4.62e-051921496ba2a683472a8b785dbf666dc6e94356d879486c3
ToppCell343B-Lymphocytic-ILC-ILC-1|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

CLASP2 NSUN2 ELAC2 YIPF2 TBC1D31 MGRN1

4.62e-051921496445985fe1bcd33e4f0a1704b27988fbfc9334538
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DPP10 NRXN3 NRXN2 CAMKV CRACDL ATP2B4

4.76e-051931496be28070c049e7cb68bcd54f582226eb2f5e4bc1c
ToppCellsevere-low-quality_cells|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

FRAS1 EML4 FRYL CDK13 ATAD2B BRWD1

4.76e-0519314969337bc93e3904c7fc7c93c328518bcd6453b1e8c
ToppCellhuman_hepatoblastoma-Tumor_cells-T1|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

KIF4A RFWD3 FANCD2 TBC1D31 BRCA1 RACGAP1

4.76e-0519314964b9fa2a4424f8abe63fa7bee78db93dda04ab15f
ToppCellhuman_hepatoblastoma-Tumor_cells|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)

FRAS1 PARD3B NRXN3 TNFRSF19 HS3ST4 MED13

4.76e-051931496503a979328c68b096680b71359a26f02fafdff35
ToppCellwk_20-22-Hematologic_Lymphocytic-T_&_ILC-Cycling_T|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

KIF4A FANCD2 CAMKV CDCA7 RACGAP1 TMPO

4.76e-05193149681e6240cffb094b2aa3684fd0889b6497f47c4f0
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DPP10 NRXN3 NRXN2 CAMKV CRACDL ATP2B4

4.76e-0519314960c652ebe22ce5d2927599dd97ef1920547858395
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DPP10 NRXN3 NRXN2 CAMKV CRACDL ATP2B4

4.76e-0519314968689a70a33a7c3823dc647d41ac0160e7c3ae396
ToppCell3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_T/NK-T_cell-T_cells_proliferating-T_cells_proliferating_L.1.1.3.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TTF2 KIF4A FANCD2 BRCA1 CDCA7 TMPO

4.76e-051931496b835d28de9daeec5213172c96f62b332cda53bb5
ToppCellfacs-Marrow-KLS-18m-Hematologic-MPP_Fraction_B_+_C|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STXBP4 GART NSUN2 CDCA7 CENPV ATP2B4

4.90e-051941496c9ebdcc2ea600975dade68a41fa65d1f8a5a5926
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_myocytic-mes_proliferating_SM_(20)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

TTF2 KIF4A FANCD2 BRCA1 CDCA7 ADAMTSL2

4.90e-051941496590a9d4f054e6a3685daf752c9354650fcc7d18a
ToppCell3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_T/NK-T_cell-T_cells_proliferating|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TTF2 KIF4A FANCD2 BRCA1 CDCA7 TMPO

5.04e-05195149667670d16ddd5d5ab7bc2254df329f5a7b2581556
ToppCellfacs-Thymus-nan-3m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF4A RFWD3 BRCA1 CDCA7 RACGAP1 TMPO

5.04e-05195149693c345e70d6c8ff5d12fd63d73228c1700b804a0
ToppCell3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_T/NK-T_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TTF2 KIF4A FANCD2 BRCA1 CDCA7 TMPO

5.04e-05195149623dc2f8a3a038195a31feee7e3a51094a7a7c23e
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

RNF19A EML4 ZNF507 PTPN4 BORCS5 MBNL2

5.04e-051951496ed5f772c82d4dfd1c8735224446ec9feae3fb8c2
ToppCell10x_3'_v2v3-Neoplastic-Stem-like-NPC-like-NPC-like_Prolif-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

DOK6 LIMA1 DPP10 KIF4A RACGAP1 CENPV

5.33e-051971496196eaecef7003ed83f323c1f157c6a3594650097
ToppCellTransverse-T_cell-cycling_gd_T|Transverse / Region, Cell class and subclass

FANCD2 SLC9A5 BRCA1 CDCA7 RACGAP1 TMPO

5.48e-0519814965131b0b7d6c4dd8872cef9f2e233f59f751b4690
ToppCellTransverse-(1)_T_cell-(18)_cycling_gd_T|Transverse / shred on region, Cell_type, and subtype

FANCD2 SLC9A5 BRCA1 CDCA7 RACGAP1 TMPO

5.48e-051981496396dddf7ebad41c3a91329b6a280623c0dfdcd2f
ToppCellcycling_basal_cell|World / shred by cell class for turbinate

KIF4A FANCD2 BRCA1 CDCA7 RACGAP1 TMPO

5.48e-051981496e86c1224f5b0890a50a25257628e90c790aae7cd
ToppCellremission-T/NK_proliferative|remission / disease stage, cell group and cell class

KIF4A FANCD2 BRCA1 CDCA7 RACGAP1 TMPO

5.64e-051991496303a5fc43a48b05b6f2060d99eef4adc36f8d4e3
ToppCelltumor_Lung-T/NK_cells-Undetermined|tumor_Lung / Location, Cell class and cell subclass

KIF4A FANCD2 BRCA1 CDCA7 RACGAP1 TMPO

5.64e-0519914962e222e2e080bc2be63d0fdf285e1790676b911ef
ToppCellremission-T/NK_proliferative|World / disease stage, cell group and cell class

KIF4A FANCD2 BRCA1 CDCA7 RACGAP1 TMPO

5.64e-051991496f305f3a454b7d2170429bad087480ccccca19acd
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-3.5_mon-Proliferating-Cycling_IN_Progenitors|3.5_mon / Sample Type, Dataset, Time_group, and Cell type.

KIF4A FANCD2 BRCA1 CDCA7 RACGAP1 TMPO

5.64e-051991496f315ec3fb6c0799668c9195f836a77fc0db2b615
ToppCellLung_Parenchyma-Severe-Epithelial-Epithelial-Basal_3-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

LIMA1 ARHGEF5 SHB ARHGEF35 PER2 PTPRZ1

5.80e-05200149641705bbba40eb5ddca0b223191aac1bce00163b8
ToppCellBrain_organoid-organoid_Tanaka_cellReport-3m-Stem_cells-Neuroepithelial_cell|3m / Sample Type, Dataset, Time_group, and Cell type.

KIF4A FANCD2 BRCA1 CDCA7 RACGAP1 TMPO

5.80e-0520014962938a029fa0478be561574ace91f95c4a528b2d4
ToppCellParenchymal-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Duct|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FRAS1 MUC16 NRXN3 FCGBP PER2 PTPRZ1

5.80e-052001496b992eeddee38e6fe3564e9b1850f6b20b89bf47d
ToppCellhealthy_donor-Lymphocytic-Proliferative_Lymphocyte|healthy_donor / Disease condition, Lineage, Cell class and subclass

KIF4A FANCD2 BRCA1 CDCA7 RACGAP1 KIF4B

5.80e-052001496e4eb915c29909cf8535a3603c68976545c05e54b
ToppCellTracheal-NucSeq-Epithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MYRIP MUC16 TMTC2 PTPRJ CRACDL TNFRSF19

5.80e-052001496d3af0a706baf66e3f32e67b17dcfc31e5b32ce0e
ToppCellBrain_organoid-organoid_Tanaka_cellReport-5w-Neuronal-Intermediate|5w / Sample Type, Dataset, Time_group, and Cell type.

GATAD2B CEP170 RUNDC3A NRXN3 NRXN2 NAV1

5.80e-052001496c92e4fc0442404481fcac623d691dae6215b852d
ToppCellParenchyma_COVID-19-Epithelial-TX-Basal_3|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

LIMA1 ARHGEF5 SHB ARHGEF35 PER2 PTPRZ1

5.80e-05200149653e04399d0308b40ae99fbfaa4ff62bf061822d8
ToppCellBrain_organoid-organoid_Tanaka_cellReport-3m-Stem_cells|3m / Sample Type, Dataset, Time_group, and Cell type.

KIF4A FANCD2 BRCA1 CDCA7 RACGAP1 TMPO

5.80e-052001496cfe017b4a4d604a553d0a3df9659687f38e9a7af
ToppCellNon-neuronal-Dividing-IPC-IPC-div2|World / Primary Cells by Cluster

TTF2 KIF4A SLCO4C1 BRCA1 CDCA7 TMPO

5.80e-0520014964923d7a4f00853c4d76fc1cc0fa82d522a2302e7
ToppCellhealthy_donor-Lymphocytic-Proliferative_Lymphocyte-|healthy_donor / Disease condition, Lineage, Cell class and subclass

KIF4A FANCD2 BRCA1 CDCA7 RACGAP1 KIF4B

5.80e-052001496415e7556b5ac45688e2c6c30a52bd40e0eb27c7d
ToppCellCOVID_non-vent-Lymphocytic-Proliferative_Lymphocyte-|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

KIF4A FANCD2 BRCA1 CDCA7 RACGAP1 TMPO

5.80e-05200149604bf9e6a0fbd792b49eed63dabba5d6fafed8c07
ToppCell3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-immature_mesenchymal_cell-cycling_stromal|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KIF4A FANCD2 BRCA1 CDCA7 RACGAP1 TMPO

5.80e-05200149643571c9284d4e41402a2d1eefc1efe2ce8476d4a
ToppCellNon-neuronal-Dividing-IPC-IPC-div2-5|World / Primary Cells by Cluster

TTF2 KIF4A SLCO4C1 BRCA1 CDCA7 TMPO

5.80e-052001496dc1c1506823eaa105f1532c6b5d4efa14e788314
ToppCellCOVID-19-COVID-19_Convalescent-Lymphocyte-T/NK-T/NK_proliferative|COVID-19_Convalescent / Disease, condition lineage and cell class

KIF4A FANCD2 BRCA1 CDCA7 RACGAP1 TMPO

5.80e-05200149600538c4cbab5da00b3a366717d38a3ba5cfe3f65
ToppCellNon-neuronal-Dividing-Radial_Glia-vRG|World / Primary Cells by Cluster

KIF4A FANCD2 BRCA1 CDCA7 RACGAP1 TMPO

5.80e-0520014967596143925cd403ec7baceef87d19d570e48586a
ToppCellLung_Parenchyma-Severe-Epithelial-Epithelial-Basal_3|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

LIMA1 ARHGEF5 SHB ARHGEF35 PER2 PTPRZ1

5.80e-052001496cc8df398532c9324fd3e171000b1ea5c208cd691
ToppCellCOVID_vent-Lymphocytic-Proliferative_Lymphocyte-|COVID_vent / Disease condition, Lineage, Cell class and subclass

KIF4A FANCD2 BRCA1 CDCA7 RACGAP1 TMPO

5.80e-0520014967e4c0db43a03ca11380a54f44a3cf1991e055b80
ToppCellNon-neuronal-Dividing-Radial_Glia-vRG-17|World / Primary Cells by Cluster

KIF4A FANCD2 BRCA1 CDCA7 RACGAP1 TMPO

5.80e-0520014964417f14d45ce683c1a45ec989ae63ee6c047353e
ToppCellCOVID_non-vent-Lymphocytic-Proliferative_Lymphocyte|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

KIF4A FANCD2 BRCA1 CDCA7 RACGAP1 TMPO

5.80e-052001496f6b5320cdfe640a71e6e2df26f30d42e64b1c921
ToppCellBrain_organoid-organoid_Tanaka_cellReport-2m-Neuronal-Intermediate|2m / Sample Type, Dataset, Time_group, and Cell type.

GART RUNDC3A PTPRZ1 CENPV KAT6B ANKS1A

5.80e-0520014962a635694844ddabcd98462c5636a6f41a3f08a46
ToppCell3'-GW_trimst-1-LargeIntestine-Neuronal|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RUNDC3A NRXN2 CAMKV PTPRZ1 CENPV TNFRSF19

5.80e-052001496553e9612874480f4d2a45671462e266cd0a09321
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-3.5_mon-Proliferating|3.5_mon / Sample Type, Dataset, Time_group, and Cell type.

KIF4A FANCD2 BRCA1 CDCA7 RACGAP1 TMPO

5.80e-0520014962154c976f96489d0fa7bfe6ac1cd21edcbefe735
ToppCellBrain_organoid-organoid_Tanaka_cellReport-6m-Stem_cells-Neuroepithelial_cell|6m / Sample Type, Dataset, Time_group, and Cell type.

KIF4A FANCD2 BRCA1 CDCA7 RACGAP1 TMPO

5.80e-05200149655501f83409e0174c756a13ad8077f5b59975e27
ToppCellBrain_organoid-organoid_Tanaka_cellReport-6m-Stem_cells|6m / Sample Type, Dataset, Time_group, and Cell type.

KIF4A FANCD2 BRCA1 CDCA7 RACGAP1 TMPO

5.80e-052001496b9aad527d3ad5bc701e93fa2afdebf695b2a74bb
ToppCellCOVID_vent-Lymphocytic-Proliferative_Lymphocyte|COVID_vent / Disease condition, Lineage, Cell class and subclass

KIF4A FANCD2 BRCA1 CDCA7 RACGAP1 TMPO

5.80e-0520014969775ca7dedb76fcbb74f80f86b33c94e394c320a
DiseaseFanconi anemia (is_implicated_in)

RFWD3 FANCD2 BRCA1

1.33e-05101443DOID:13636 (is_implicated_in)
DiseaseCryptophthalmos syndrome

FRAS1 FREM2

7.07e-0531442C0265233
DiseaseFRASER SYNDROME 1

FRAS1 FREM2

7.07e-0531442C4551480
DiseaseIntellectual Disability

TCF20 PEX6 KIF4A NSUN2 KMT2C BRCA1 NRXN2 MSL3 NT5C2 MED13

7.27e-0544714410C3714756
DiseaseFraser syndrome (implicated_via_orthology)

FRAS1 FREM2

1.41e-0441442DOID:0090001 (implicated_via_orthology)
Diseaseurate measurement, bone density

RAD52 FRAS1 TRPC6 MARCHF7 DGKD CLASP2 FBXL4 BORCS5 NAV1 KAT6B ATP2B4

2.39e-0461914411EFO_0003923, EFO_0004531
DiseaseFanconi Anemia

RFWD3 FANCD2 BRCA1

2.42e-04251443C0015625
Diseaseprimary ciliary dyskinesia (is_implicated_in)

STK36 BRWD1

3.50e-0461442DOID:9562 (is_implicated_in)
Diseaselung cancer (is_implicated_in)

RAD52 RBM10 SETDB1 DAGLA

4.80e-04741444DOID:1324 (is_implicated_in)
DiseaseUnilateral agenesis of kidney

FRAS1 FREM2

6.50e-0481442C0266294
Diseasebreast cancer, ovarian carcinoma

ARHGEF5 STXBP4 CDCA7

7.83e-04371443EFO_0001075, MONDO_0007254
Diseasecolorectal cancer

LIMA1 DPP10 TRPC6 KIAA0319 CCDC195 EIF4ENIF1 PRICKLE2 HS3ST4 CDH15 PCNT

7.93e-0460414410MONDO_0005575
DiseaseAutism Spectrum Disorders

DPP10 NSUN2 NRXN3 NRXN2

8.11e-04851444C1510586
Diseaseattention deficit hyperactivity disorder, conduct disorder

ARHGAP9 PKD1L2 KIAA2012

9.85e-04401443EFO_0003888, EFO_0004216
DiseaseFacies

MSL3 ADAMTSL2

1.04e-03101442C0282631
DiseaseCongenital small ears

FRAS1 LEMD3 FREM2

1.06e-03411443C0152423
DiseasePancreatic Ductal Adenocarcinoma

ACACB ABLIM2

1.26e-03111442C1335302
DiseaseBipolar I disorder

NRXN3 KAT6B

1.26e-03111442C0853193
DiseaseMouth Diseases

GDF15 BRCA1

1.51e-03121442C0026636
Diseasesevere acute respiratory syndrome, COVID-19

GDF15 MYRIP C10orf90 PTPN4 BORCS5 MBNL2 PRICKLE2 HS3ST4

1.63e-034471448EFO_0000694, MONDO_0100096
Diseasecardiac troponin I measurement

DPP10 TMTC2 PARD3B ELAC2 MBNL2

1.76e-031761445EFO_0010071
Diseaselung adenocarcinoma (is_implicated_in)

RBM10 KMT2C PTPRJ

1.78e-03491443DOID:3910 (is_implicated_in)
Diseasenausea and vomiting of pregnancy severity measurement

GDF15 TRPC6

2.07e-03141442EFO_0009265
Diseaseautism spectrum disorder (is_implicated_in)

MBD6 MBD5

2.71e-03161442DOID:0060041 (is_implicated_in)
Diseasecolorectal cancer (is_implicated_in)

RAD52 RBM10 BRCA1 PTPRJ

2.97e-031211444DOID:9256 (is_implicated_in)
Diseasecolorectal health

VWA8 EML4 PKD1L1 NRXN3 ANKS1A

3.13e-032011445EFO_0008460
Diseasemigraine disorder, type 2 diabetes mellitus

FRYL DNAI4 KIAA2012

3.18e-03601443MONDO_0005148, MONDO_0005277
Diseasecystathionine measurement

DOK6 PARD3B

3.83e-03191442EFO_0010474
DiseaseProstate cancer, familial

ELAC2 BRCA1 CDCA7

4.71e-03691443C2931456

Protein segments in the cluster

PeptideGeneStartEntry
RQPSVDLTDDDQTSS

CEP170

1016

Q5SW79
DRSSNAEPLQVLSVS

CTRL

91

P40313
LDSSSNERPDISSIQ

NT5C2

406

P49902
PSSNLSSLSNASERD

BRD9

546

Q9H8M2
QTESRAEELSPAALS

ARHGEF5

436

Q12774
QDSQESISNLERPSS

ARHGEF5

671

Q12774
SQLDLEDTQIPTSRS

SPATA5

236

Q8NB90
QTESRAEELSPAALS

ARHGEF35

436

A5YM69
ILRRSSSESPSDNQA

C1orf216

56

Q8TAB5
RNTDSPRAALSSSEL

ANKIB1

901

Q9P2G1
SSPTDNLELSLRSQS

GIT1

361

Q9Y2X7
DTRTNSPDLDTQSLS

ABLIM2

471

Q6H8Q1
DLLSQTSSPLSQNDS

ANKS1A

851

Q92625
LLSSPDSEQRQSVEA

DCAF6

436

Q58WW2
EVLLNTPGSRSSEQS

C2orf73

191

Q8N5S3
DLSLGLDDSRTNTPQ

CDK13

1046

Q14004
LTPDELTNSSETRLS

DPP10

56

Q8N608
QLPQSDSSLQSLETS

ATP2B4

1226

P23634
SEPSSENANDTIILR

RBM10

291

P98175
SSERNQDRKESSPNS

NSRP1

446

Q9H0G5
SSRADPAQTSDTLAL

RAD52

346

P43351
RNPVSEELQVSSSSD

RFWD3

201

Q6PCD5
NSISDDRLETQSLPS

PTPN4

376

P29074
TRADQSPQIATTLDD

KAT6B

1576

Q8WYB5
PLAASEVTNSNSAER

LEMD3

176

Q9Y2U8
SAETRESTQLSPADL

NSUN2

446

Q08J23
NSPTELNKDRTSRDS

RBL2

951

Q08999
ATLADEQSRASSPQS

RAD9B

271

Q6WBX8
EATDTNGLSSSARPQ

ACACB

126

O00763
LPTEEVRSQASDDSS

DEPDC5

511

O75140
NELPSDSSSSSDLIN

MUC16

2361

Q8WXI7
TDSPETDASASLQQN

PARD3B

336

Q8TEW8
RNSNSSRQDITLEPS

MBD6

961

Q96DN6
ETDSSNLNVSEPRAV

PTPRJ

406

Q12913
NLSSTTDDEAPRLSQ

LAD1

36

O00515
ISNSSLSLQDLDTPD

FRAS1

1976

Q86XX4
SSDTTPLLNGSSQDR

GOSR1

51

O95249
PTLQRSVSEESANSL

KMT2C

106

Q8NEZ4
QQDSIDPSSRIDSEL

KMT2C

1721

Q8NEZ4
DISQAAQILSSDPSR

TMPO

596

P42166
SANENSLAVRSTPAE

LIMA1

326

Q9UHB6
ESLLVNSSSSLNPEQ

ATAD2B

1241

Q9ULI0
GSPSALSDQTTERQL

ASPDH

96

A6ND91
TRAASIENVLQDSSP

MGRN1

511

O60291
TDLLSTSDLNSPDEN

FREM2

1441

Q5SZK8
DSLTSNRTSQRASPE

CCDC195

141

A0A1B0GUA6
LTRDEPSDTQNSDAL

PER2

1036

O15055
ATTSRAQDLPADVQT

PEX6

571

Q13608
ETPTLEASLDNANSR

FRYL

2546

O94915
EASLDNANSRLPEDT

FRYL

2551

O94915
ESATSTNRSQEELSP

MSL3

296

Q8N5Y2
RSPTLRDSTTQNTDD

NRXN2

1381

Q9P2S2
NRSTASIQPTSDDLV

NRXN3

1301

Q9Y4C0
AQESQVSLDGRSSPS

KIAA2012

936

Q0VF49
ELSSDRVANSSSEAP

ADAMTSL2

516

Q86TH1
ELTQAPTRQATSEAT

GDPD4

586

Q6W3E5
SDQLLAESSSARPQL

GDF15

166

Q99988
IVLSDNEASSPRSSS

GATAD2B

126

Q8WXI9
SLVSTRQEENPSTSL

PTPRZ1

2281

P23471
NSRLERSLTASQDPE

PCNT

3286

O95613
DSTVSARISDNSLAP

CRACDL

191

Q6NV74
SLSNRPEEPAEASSS

PKD1L2

1016

Q7Z442
LARTVNDDQSPSTLN

PIK3C2B

471

O00750
TRSSLPSLDDQEQAS

PARD6A

316

Q9NPB6
SPTLRDSTTQNTDDL

NRXN2

336

P58401
SSNRLSADVDPLSLQ

PRICKLE2

361

Q7Z3G6
PLEQSNSALSESSAA

PLCB3

486

Q01970
SSLPLNSLSRNNEVD

ATP6AP2

166

O75787
SSALEDLRNPEQSTS

BRCA1

1436

P38398
TEAALQDLSSPRLSQ

GASK1A

296

Q9UFP1
SPSNDLDSVSVNSLD

CDHR2

1236

Q9BYE9
RDSANATSLPVQDSS

IL6R

346

P08887
LRAPEQSSTAAAQSA

CAMKV

326

Q8NCB2
LISTDSGNSLPERNS

DOCK9

1256

Q9BZ29
EQSEEAQQPLSRSSS

DOK6

306

Q6PKX4
RAIESNSQTSPLNAE

FBXL4

36

Q9UKA2
SESPASVSILSQADN

FCGBP

61

Q9Y6R7
TDQDGSDSPRSSLNN

FOXJ3

216

Q9UPW0
SDSPRSSLNNSLSDQ

FOXJ3

221

Q9UPW0
SSEAESRPNDLNSSV

BORCS5

6

Q969J3
TPTSSASNLDLGEQR

CENPV

101

Q7Z7K6
LTDLNPAASRTTTEN

CEP350

1296

Q5VT06
SLPSVNDIEASVNRS

CEP350

2616

Q5VT06
LPQEASNRSLNATET

HTR1D

11

P28221
QTNDNDERSPESSIL

BRWD1

641

Q9NSI6
ATSSSSQDPESLQDR

SERPING1

26

P05155
SSPRVLSNNSDANLE

SERPING1

246

P05155
TPATSIDNSEIISRN

MBNL2

326

Q5VZF2
LTASQSRSNVPSASE

MARCHF7

321

Q9H992
DLVLEEQSPSSSNSL

MBD5

1311

Q9P267
EQSPSSSNSLENSLV

MBD5

1316

Q9P267
KTLDDESQASSSLPN

DGKD

551

Q16760
NPSLSSRTELLAADS

DAGLA

831

Q9Y4D2
VRSNSNVPVLDSSES

DNAI4

566

Q5VTH9
PSAVRLQESDSLATS

FOXN2

281

P32314
AQVETSPETSRSSDA

KIF4A

496

O95239
AQVETSPETSRSSDA

KIF4B

496

Q2VIQ3
EESSSQVLPSSSQRL

KANSL3

886

Q9P2N6
LNETAEEESRISSSP

EML4

906

Q9HC35
NSDVLQSPLDSAARD

COLGALT1

606

Q8NBJ5
QDDASQPRTATGTLS

CDH15

456

P55291
DRESQSPSSSASRQK

PKD1L1

81

Q8TDX9
RLPEEDASSQSSKTN

HELB

701

Q8NG08
TAQSALPEREAQESS

HS3ST4

151

Q9Y661
ESPSLTQERANLSDE

FANCD2

591

Q9BXW9
LNQESSGIPSSLETR

ALOX15B

521

O15296
SDDANPRSVSSLSNR

NAV1

296

Q8NEY1
EPLSAEASLSSDSQR

RUNDC3A

371

Q59EK9
SLAQPESIRSDLESS

RNF19B

656

Q6ZMZ0
QSVDSDSESTVSPRL

SHB

306

Q15464
DSSCLPRTSQLNDSS

TBC1D31

1001

Q96DN5
NSQEDPADTASVRSL

LINC00869

26

P0C866
NRSTASIQPTSDDLV

NRXN3

296

Q9HDB5
LSSNEDDANILSSPT

MED24

861

O75448
RELSGTPNLLNTSDS

PRDM7

131

Q9NQW5
SRSESSADLPQQQEL

SLC9A5

851

Q14940
DSASQRLVISAPDSQ

MED13

491

Q9UHV7
ASESSLERPEESISN

IMPG2

211

Q9BZV3
SGSSRQPDSLSSIEN

IMPG2

1141

Q9BZV3
PDNISSASTSNIARI

PHLDB2

1021

Q86SQ0
FSDNSTPLSNLSERR

STXBP4

441

Q6ZWJ1
NSDSTLNSRQLEPRT

RACGAP1

256

Q9H0H5
AALRTQTLPSENSEE

RIOX1

51

Q9H6W3
LANQLTEDSSQLRPS

STK36

686

Q9NRP7
SAQSNPDDVLTLSSS

SETDB1

1091

Q15047
ENLLSSSSVPSADRD

EIF4ENIF1

736

Q9NRA8
DEPTTLTTNALDLNS

AIMP2

96

Q13155
SRQPSENSVTDSNSD

CDCA7

91

Q9BWT1
SLKESPLRDQQESST

C12orf56

156

Q8IXR9
DRSSSSSQESLNRPF

CLASP2

321

O75122
SEDCSESQQTPARSL

C10orf90

556

Q96M02
DSLRTSPSVASLSEN

TTPAL

6

Q9BTX7
DQSELSQLDPASSRS

RETREG3

451

Q86VR2
SLTDSSESVSGQRPN

WDFY3

2661

Q8IZQ1
RLSPERSSDSESNEN

ELAC2

206

Q9BQ52
LSSDEATNPISRVLN

NUFIP2

111

Q7Z417
DRDLQSSASSVSLPS

RNF19A

41

Q9NV58
EVSALSSDPQRENSQ

SLCO4C1

31

Q6ZQN7
SDNPAADSDSLLTRT

TMTC2

256

Q8N394
STEQRLSDLNTPEES

SORBS1

1161

Q9BX66
SSSSSLQSREEKQEP

SAP130

81

Q9H0E3
ENIESPLNERDSSAS

USP47

906

Q96K76
ELSQALPSRAQASSE

ARHGAP9

116

Q9BRR9
SPNIRRSASSNSAEA

TCF20

1361

Q9UGU0
LQALIDSTREPNSSA

GART

821

P22102
SRSNTEDLPLTLESA

TRBV10-1

86

A0A0K0K1A3
SPEELSSLSAAQRNL

ZIM2

186

Q9NZV7
ANILPEETSSSASDQ

ZNF264

601

O43296
QLSSSSPLEQSAERG

ZNF507

331

Q8TCN5
PSSELTSQRQNDLSD

ZXDA

586

P98168
SLNPELESSTSLDSN

TNFRSF19

336

Q9NS68
NLEASSSDEQPASLT

ZBTB2

221

Q8N680
RLATSPSQSELQQDD

TRPC6

191

Q9Y210
ERSPSDNSLNTTGII

TRAPPC10

681

P48553
TNLLADTPDAATTSR

YIPF2

16

Q9BWQ6
DTPDAATTSRSDQLT

YIPF2

21

Q9BWQ6
QDPTAQSLAASLSTR

VWA8

646

A3KMH1
SDRDISSATDLQPDQ

TTLL4

491

Q14679
QTASELTRPQDSISS

ZNF284

106

Q2VY69
SELRDSEPSSTVSLN

TTF2

961

Q9UNY4
LPNNSITLDGSRSTD

KIAA0319

731

Q5VV43
SETDISNEARDPQTL

MYRIP

561

Q8NFW9