Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionstructural constituent of postsynaptic actin cytoskeleton

POTEF POTEE POTEI

3.37e-05111203GO:0098973
GeneOntologyMolecularFunctioncorticotropin-releasing hormone receptor 1 binding

CRH GNAS

2.13e-0441202GO:0051430
GeneOntologyMolecularFunctionproteoglycan binding

FN1 PTPRF CHRD NID1

2.49e-04511204GO:0043394
GeneOntologyMolecularFunctioncytoskeleton-nuclear membrane anchor activity

SYNE1 SYNE2

3.54e-0451202GO:0140444
GeneOntologyMolecularFunctioncorticotropin-releasing hormone receptor binding

CRH GNAS

5.29e-0461202GO:0051429
GeneOntologyMolecularFunctionhistone H3K4me/H3K4me2/H3K4me3 demethylase activity

KDM5C KDM5D

5.29e-0461202GO:0034647
GeneOntologyMolecularFunctionstructural constituent of postsynapse

POTEF POTEE POTEI

9.24e-04321203GO:0099186
GeneOntologyMolecularFunctionhistone H3K4 demethylase activity

KDM5C KDM5D

9.79e-0481202GO:0032453
DomainNPIP

NPIPB3 NPIPB5 NPIPB2 NPIPB13

1.70e-06141234IPR009443
Domainfn3

CNTN4 SDK2 FN1 PTPRF IGSF9B TNXB SDK1

9.92e-051621237PF00041
DomainUAS

FAF2 UBXN7

1.29e-0431232SM00594
DomainUAS

FAF2 UBXN7

1.29e-0431232IPR006577
DomainActin_CS

POTEF POTEE POTEI

1.47e-04161233IPR004001
DomainACTINS_2

POTEF POTEE POTEI

1.77e-04171233PS00432
DomainActin/actin-like_CS

POTEF POTEE POTEI

2.12e-04181233IPR020902
DomainFN3

CNTN4 SDK2 FN1 PTPRF IGSF9B TNXB SDK1

2.26e-041851237SM00060
DomainACTINS_ACT_LIKE

POTEF POTEE POTEI

2.50e-04191233PS01132
DomainLys_sp_deMease-like_dom

KDM5C KDM5D

2.56e-0441232IPR013637
DomainDUF2476

PRR23A PRR23B

2.56e-0441232PF10630
DomainKASH

SYNE1 SYNE2

2.56e-0441232IPR012315
DomainG2F

HMCN2 NID1

2.56e-0441232PF07474
DomainKASH

SYNE1 SYNE2

2.56e-0441232PS51049
DomainKASH

SYNE1 SYNE2

2.56e-0441232SM01249
DomainPRR23

PRR23A PRR23B

2.56e-0441232IPR018903
DomainNIDOGEN_G2

HMCN2 NID1

2.56e-0441232PS50993
DomainKASH

SYNE1 SYNE2

2.56e-0441232PF10541
DomainGFP

HMCN2 NID1

2.56e-0441232IPR009017
DomainPLU-1

KDM5C KDM5D

2.56e-0441232PF08429
DomainG2_nidogen/fibulin_G2F

HMCN2 NID1

2.56e-0441232IPR006605
DomainIg_I-set

CNTN4 SDK2 HMCN2 PTPRF ALPK3 IGSF9B SDK1

2.65e-041901237IPR013098
DomainI-set

CNTN4 SDK2 HMCN2 PTPRF ALPK3 IGSF9B SDK1

2.65e-041901237PF07679
DomainFN3

CNTN4 SDK2 FN1 PTPRF IGSF9B TNXB SDK1

3.51e-041991237PS50853
Domainzf-C5HC2

KDM5C KDM5D

4.25e-0451232PF02928
DomainZnf_C5HC2

KDM5C KDM5D

4.25e-0451232IPR004198
DomainSpectrin

SYNE1 SPTBN1 SYNE2

4.48e-04231233PF00435
DomainACTININ_2

SYNE1 SPTBN1 SYNE2

4.48e-04231233PS00020
DomainACTININ_1

SYNE1 SPTBN1 SYNE2

4.48e-04231233PS00019
DomainActinin_actin-bd_CS

SYNE1 SPTBN1 SYNE2

4.48e-04231233IPR001589
DomainFN3_dom

CNTN4 SDK2 FN1 PTPRF IGSF9B TNXB SDK1

4.72e-042091237IPR003961
DomainZinc_finger_PHD-type_CS

NSD2 KDM5C KDM5D CHD5

8.89e-04651234IPR019786
DomainCH

SYNE1 SPTBN1 MICALL2 SYNE2

8.89e-04651234SM00033
DomainSpectrin_repeat

SYNE1 SPTBN1 SYNE2

8.99e-04291233IPR002017
DomainIGc2

CNTN4 SDK2 HMCN2 PTPRF ALPK3 IGSF9B SDK1

9.42e-042351237SM00408
DomainIg_sub2

CNTN4 SDK2 HMCN2 PTPRF ALPK3 IGSF9B SDK1

9.42e-042351237IPR003598
DomainActin

POTEF POTEE POTEI

1.09e-03311233IPR004000
DomainActin

POTEF POTEE POTEI

1.09e-03311233PF00022
DomainACTIN

POTEF POTEE POTEI

1.09e-03311233SM00268
DomainCH

SYNE1 SPTBN1 MICALL2 SYNE2

1.17e-03701234PF00307
DomainSPEC

SYNE1 SPTBN1 SYNE2

1.20e-03321233SM00150
DomainSpectrin/alpha-actinin

SYNE1 SPTBN1 SYNE2

1.20e-03321233IPR018159
Domain-

SYNE1 SPTBN1 MICALL2 SYNE2

1.24e-037112341.10.418.10
DomainCH

SYNE1 SPTBN1 MICALL2 SYNE2

1.37e-03731234PS50021
DomainPHD

NSD2 KDM5C KDM5D CHD5

1.52e-03751234PF00628
DomainCH-domain

SYNE1 SPTBN1 MICALL2 SYNE2

1.52e-03751234IPR001715
DomainZnf_PHD-finger

NSD2 KDM5C KDM5D CHD5

1.84e-03791234IPR019787
DomainJmjN

KDM5C KDM5D

1.87e-03101232SM00545
DomainJmjN

KDM5C KDM5D

1.87e-03101232PF02375
DomainJMJN

KDM5C KDM5D

1.87e-03101232PS51183
DomainJmjN

KDM5C KDM5D

1.87e-03101232IPR003349
DomainZF_CXXC

CXXC5 DNMT1

2.28e-03111232PS51058
DomainZnf_CXXC

CXXC5 DNMT1

2.28e-03111232IPR002857
Domainzf-CXXC

CXXC5 DNMT1

2.28e-03111232PF02008
DomainZnf_C2H2_matrin

RBM20 CIZ1

2.72e-03121232IPR000690
DomainPHD

NSD2 KDM5C KDM5D CHD5

2.84e-03891234SM00249
DomainZnf_PHD

NSD2 KDM5C KDM5D CHD5

3.08e-03911234IPR001965
DomainUBX_dom

FAF2 UBXN7

3.20e-03131232IPR001012
DomainUBX

FAF2 UBXN7

3.20e-03131232PF00789
DomainUBX

FAF2 UBXN7

3.20e-03131232PS50033
DomainZF_PHD_2

NSD2 KDM5C KDM5D CHD5

3.59e-03951234PS50016
DomainZF_PHD_1

NSD2 KDM5C KDM5D CHD5

3.73e-03961234PS01359
Domain-

KDM5C KDM5D

4.27e-031512321.10.150.60
DomainBRIGHT

KDM5C KDM5D

4.27e-03151232SM00501
DomainARID_dom

KDM5C KDM5D

4.27e-03151232IPR001606
DomainARID

KDM5C KDM5D

4.27e-03151232PS51011
DomainARID

KDM5C KDM5D

4.27e-03151232PF01388
DomainPost-SET_dom

SETD1A NSD2

4.86e-03161232IPR003616
DomainPostSET

SETD1A NSD2

4.86e-03161232SM00508
DomainPOST_SET

SETD1A NSD2

4.86e-03161232PS50868
Domain-

SETD1A PPRC1 R3HCC1 RBM20 RBM6 SNRNP70

5.58e-0324412363.30.70.330
DomainZF_MATRIN

RBM20 CIZ1

6.14e-03181232PS50171
DomainANK

ASPG POTEF ANKHD1 POTEE NFKBIL1 POTEI

6.38e-032511236SM00248
Pubmed

Human transcription factor protein interaction networks.

GTPBP4 IRF2BP2 SETD1A RBBP6 SPTBN1 FBRS RCN1 SMG5 ANKHD1 RBM20 GATAD2B ZNF512B CHD5 MDC1 SYNE2 UBXN7 YLPM1 NFRKB MKI67 RBM6 LSM14A SNRNP70 CABIN1 PRRC2A ZMYM3 TP53BP1

1.06e-1114291272635140242
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

GTPBP4 FN1 CENPF NSD2 SPTBN1 ANKHD1 THOC2 MDC1 SYNE2 YLPM1 MKI67 RBM6 BOP1 SNRNP70 PRRC2A ZMYM3 TP53BP1 DNMT1

3.25e-116531271822586326
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

IRF2BP2 RBBP6 C9orf78 SEPTIN9 KDM5C SPTBN1 THOC2 GATAD2B CBFA2T2 MDC1 YLPM1 NFRKB MKI67 RBM6 PRRC2A ZMYM3 TP53BP1 DNMT1

4.99e-107741271815302935
Pubmed

A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

CENPF RBBP6 SEPTIN9 KDM5C THOC2 GATAD2B MKI67 RBM6 BOP1 SNRNP70 PRRC2A EPB41L1 TP53BP1 SH3BP5

5.11e-095031271416964243
Pubmed

Nuclear actin interactome analysis links actin to KAT14 histone acetyl transferase and mRNA splicing.

GTPBP4 IRF2BP2 CENPF RBBP6 SEPTIN9 POTEF SPTBN1 GATAD2B MDC1 YLPM1 MKI67 POTEI SNRNP70 TP53BP1

5.51e-095061271430890647
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

GTPBP4 CNTN4 SGIP1 CENPF PATZ1 SYNE1 SPTBN1 SIPA1 GATAD2B SYNE2 YLPM1 CABIN1 PRRC2A EPB41L1 WNK2 TP53BP1 DNMT1 SH3BP5

1.50e-089631271828671696
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

GTPBP4 RBBP6 NSD2 PATZ1 KDM5C ZNF316 FBRS RCN1 C16orf96 SIPA1 ANKHD1 GATAD2B ZNF512B HMCN2 CHD5 NFKBIL1 NFRKB CIZ1 ZMYM3

2.54e-0811161271931753913
Pubmed

The in vivo Interaction Landscape of Histones H3.1 and H3.3.

GTPBP4 NSD2 C9orf78 GATAD2B ZNF512B CHD5 MDC1 NFRKB CIZ1 MKI67 BOP1 CABIN1 ZMYM3 DNMT1

5.44e-086081271436089195
Pubmed

Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.

SETD1A RBBP6 KDM5D FAM186B FAF2 CBFA2T2 CHD5 MDC1 NFKBIL1 YLPM1 IGSF9B WNK2

6.54e-084301271235044719
Pubmed

Unbiased Identification of trans Regulators of ADAR and A-to-I RNA Editing.

SEPTIN9 POTEF SPTBN1 THOC2 POTEE CHD5 MDC1 MKI67 POTEI TP53BP1

6.57e-082711271032433965
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

TCEA2 RBBP6 NSD2 SEPTIN9 THOC2 GATAD2B ZNF512B MDC1 YLPM1 NFRKB CIZ1 MKI67 RBM6 SNRNP70 PRRC2A TP53BP1 DNMT1

7.74e-089541271736373674
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

SETD1A SDK2 SZT2 NSD2 KDM5C SMG5 ANKHD1 ZNF512B CHD5 MDC1 UBXN7 BOP1 WNK2

7.91e-085291271314621295
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

SETD1A GAK RBBP6 ANKHD1 THOC2 MDC1 YLPM1 NFRKB CIZ1 PEAK1 PRRC2A TP53BP1 DNMT1

1.21e-075491271338280479
Pubmed

MMSET regulates histone H4K20 methylation and 53BP1 accumulation at DNA damage sites.

NSD2 MDC1 TP53BP1

1.90e-074127321293379
Pubmed

Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.

FN1 SEPTIN9 SPTBN1 SMG5 NFRKB NID1 BOP1 LSM14A IGSF9B PRRC2A TP53BP1 DNMT1

1.91e-074751271231040226
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

GTPBP4 CENPF RBBP6 NSD2 PATZ1 CXXC5 THOC2 GATAD2B ZNF512B MDC1 NFKBIL1 YLPM1 NFRKB CIZ1 MKI67 SNRNP70 CABIN1 ZMYM3 DNMT1

2.52e-0712941271930804502
Pubmed

Spatiotemporal-resolved protein networks profiling with photoactivation dependent proximity labeling.

IRF2BP2 RBBP6 SEPTIN9 GATAD2B MDC1 UBXN7 YLPM1 MKI67 SNRNP70 PRRC2A TP53BP1

2.67e-073991271135987950
Pubmed

Defining the NSD2 interactome: PARP1 PARylation reduces NSD2 histone methyltransferase activity and impedes chromatin binding.

GTPBP4 NSD2 GATAD2B ZNF512B MDC1 MKI67

2.70e-0772127631248990
Pubmed

SMYD3 Impedes Small Cell Lung Cancer Sensitivity to Alkylation Damage through RNF113A Methylation-Phosphorylation Cross-talk.

GTPBP4 RBBP6 PATZ1 ANKHD1 GATAD2B YLPM1 MKI67 TSPYL5 BOP1 LSM14A GNAS SNRNP70 PRRC2A

8.90e-076551271335819319
Pubmed

PTEN Methylation by NSD2 Controls Cellular Sensitivity to DNA Damage.

NSD2 MDC1 TP53BP1

9.43e-076127331217297
Pubmed

The sequence and analysis of duplication-rich human chromosome 16.

TRIM72 NPIPB11 NPIPB3 C16orf96 NPIPB2 MARVELD3

1.02e-0690127615616553
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

GTPBP4 CENPF SEPTIN9 SYNE1 RCN1 THOC2 ZNF512B PTPRF MDC1 SYNE2 YLPM1 CIZ1 MKI67 BOP1 GNAS SNRNP70

1.09e-0610241271624711643
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

GTPBP4 IRF2BP2 GAK RBBP6 SEPTIN9 ANKHD1 THOC2 ZNF512B YLPM1 CIZ1 MKI67 LSM14A PRRC2A TP53BP1 DNMT1

1.74e-069341271533916271
Pubmed

Functional proteomics mapping of a human signaling pathway.

FN1 RBBP6 SPTBN1 CXXC5 GATAD2B ZNF512B PTPRF YLPM1 NID1 PAPPA SNRNP70 SDK1

1.89e-065911271215231748
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

RBBP6 NSD2 SYNE1 CXXC5 ANKHD1 GATAD2B POTEE MICALL2 MDC1 NFRKB CIZ1 RBM6 BOP1 LSM14A PRRC2A DDX28 ZMYM3 EPB41L1 MAN1B1

2.21e-0614971271931527615
Pubmed

NuRD subunit CHD4 regulates super-enhancer accessibility in rhabdomyosarcoma and represents a general tumor dependency.

RBBP6 GATAD2B ZNF512B CHD5 MKI67 ZMYM3

2.25e-06103127632744500
Pubmed

Proteins recruited by SH3 domains of Ruk/CIN85 adaptor identified by LC-MS/MS.

IRF2BP2 SEPTIN9 CIZ1 PRRC2A DDX28 DNMT1

2.97e-06108127619531213
Pubmed

The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.

IRF2BP2 CENPF USE1 NSD2 KDM5C SPTBN1 R3HCC1 PRRC2A DNMT1

3.90e-06332127937433992
Pubmed

Mice lacking the extracellular matrix adaptor protein matrilin-2 develop without obvious abnormalities.

FN1 MATN4 NID1

3.93e-069127315296947
Pubmed

The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.

GTPBP4 CENPF RBBP6 NSD2 THOC2 MKI67 RBM6 BOP1 LSM14A SNRNP70 PRRC2A DDX28 DNMT1

4.47e-067591271335915203
Pubmed

Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.

SETD1A RBBP6 GATAD2B MDC1 UBXN7 YLPM1 PARL MKI67 TP53BP1

4.84e-06341127932971831
Pubmed

Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.

GTPBP4 SETD1A FBRS MDC1 YLPM1 MKI67 RBM6 BOP1 SNRNP70 TP53BP1

5.32e-064401271034244565
Pubmed

The functional interactome of PYHIN immune regulators reveals IFIX is a sensor of viral DNA.

GTPBP4 NSD2 GATAD2B MDC1 MKI67 BOP1 SNRNP70 CABIN1 DNMT1

5.84e-06349127925665578
Pubmed

SR protein kinases promote splicing of nonconsensus introns.

GTPBP4 SDK2 RBBP6 PATZ1 HMCN2 OTOF MDC1 SNRNP70 PRRC2A

7.66e-06361127926167880
Pubmed

A collagen VI-dependent pathogenic mechanism for Hirschsprung's disease.

FN1 GDNF MKI67

1.02e-0512127326571399
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

GAK RBBP6 KDM5C FBRS RBM20 POTEE RBM6 GNAS POTEI ZMYM3 TP53BP1

1.12e-055881271138580884
Pubmed

The functional interactome landscape of the human histone deacetylase family.

RCN1 GATAD2B ZNF512B SYNE2 YLPM1 MKI67 SNRNP70 ZMYM3

1.18e-05289127823752268
Pubmed

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.

IRF2BP2 ORC6 C9orf78 SEPTIN9 ZNF316 THOC2 GATAD2B NFRKB MKI67 LSM14A SNRNP70 PRRC2A ZMYM3 TP53BP1 DNMT1

1.28e-0511031271534189442
Pubmed

DNA damage response mediators MDC1 and 53BP1: constitutive activation and aberrant loss in breast and lung cancer, but not in testicular germ cell tumours.

MDC1 TP53BP1

1.32e-052127217546051
Pubmed

Nesprins: a novel family of spectrin-repeat-containing proteins that localize to the nuclear membrane in multiple tissues.

SYNE1 SYNE2

1.32e-052127211792814
Pubmed

Differential mRNA expression of neurotrophic factors GDNF, BDNF, and NT-3 in experimental herpes simplex virus encephalitis.

NTF3 GDNF

1.32e-052127215950786
Pubmed

The in vivo dynamic interplay of MDC1 and 53BP1 at DNA damage-induced nuclear foci.

MDC1 TP53BP1

1.32e-052127222677490
Pubmed

Nesprin-1 and nesprin-2 regulate endothelial cell shape and migration.

SYNE1 SYNE2

1.32e-052127224931616
Pubmed

Mouse H-Y encoding Smcy gene and its X chromosomal homolog Smcx.

KDM5C KDM5D

1.32e-052127210441747
Pubmed

Inefficient purifying selection: the mammalian Y chromosome in the rodent genus Mus.

KDM5C KDM5D

1.32e-052127216416087
Pubmed

A primate-specific POTE-actin fusion protein plays a role in apoptosis.

POTEF POTEE

1.32e-052127219669888
Pubmed

Sidekick-1 is upregulated in glomeruli in HIV-associated nephropathy.

SDK2 SDK1

1.32e-052127215213259
Pubmed

Mutations of histone demethylase genes encoded by X and Y chromosomes, Kdm5c and Kdm5d, lead to noncompaction cardiomyopathy in mice.

KDM5C KDM5D

1.32e-052127232081420
Pubmed

The direct interaction between 53BP1 and MDC1 is required for the recruitment of 53BP1 to sites of damage.

MDC1 TP53BP1

1.32e-052127218986980
Pubmed

Definition of the critical domains required for homophilic targeting of mouse sidekick molecules.

SDK2 SDK1

1.32e-052127215703275
Pubmed

Architecture of cell-cell adhesion mediated by sidekicks.

SDK2 SDK1

1.32e-052127230150416
Pubmed

Dynamic assembly and sustained retention of 53BP1 at the sites of DNA damage are controlled by Mdc1/NFBD1.

MDC1 TP53BP1

1.32e-052127216009723
Pubmed

αv-Class integrin binding to fibronectin is solely mediated by RGD and unaffected by an RGE mutation.

FN1 NID1

1.32e-052127233141174
Pubmed

Downregulation of MDC1 and 53BP1 by short hairpin RNA enhances radiosensitivity in laryngeal carcinoma cells.

MDC1 TP53BP1

1.32e-052127225976740
Pubmed

A mouse Y chromosome gene encoded by a region essential for spermatogenesis and expression of male-specific minor histocompatibility antigens.

KDM5C KDM5D

1.32e-05212727524912
Pubmed

Multiple novel nesprin-1 and nesprin-2 variants act as versatile tissue-specific intracellular scaffolds.

SYNE1 SYNE2

1.32e-052127222768332
Pubmed

The histone methyltransferase MMSET regulates class switch recombination.

NSD2 TP53BP1

1.32e-052127223241889
Pubmed

Distinct roles of chromatin-associated proteins MDC1 and 53BP1 in mammalian double-strand break repair.

MDC1 TP53BP1

1.32e-052127218158901
Pubmed

Syne-1 and Syne-2 play crucial roles in myonuclear anchorage and motor neuron innervation.

SYNE1 SYNE2

1.32e-052127217267447
Pubmed

Nesprins: tissue-specific expression of epsilon and other short isoforms.

SYNE1 SYNE2

1.32e-052127224718612
Pubmed

Targeted ablation of nesprin 1 and nesprin 2 from murine myocardium results in cardiomyopathy, altered nuclear morphology and inhibition of the biomechanical gene response.

SYNE1 SYNE2

1.32e-052127224586179
Pubmed

[Expression of DNA damage checkpoint mediator 1 and p53-binding protein 1 in human esophageal cancer cell lines TE-1, TE-13, and Eca109].

MDC1 TP53BP1

1.32e-052127217884766
Pubmed

Nesprin-1 and -2 are involved in the pathogenesis of Emery Dreifuss muscular dystrophy and are critical for nuclear envelope integrity.

SYNE1 SYNE2

1.32e-052127217761684
Pubmed

Nesprin-1-alpha2 associates with kinesin at myotube outer nuclear membranes, but is restricted to neuromuscular junction nuclei in adult muscle.

SYNE1 SYNE2

1.32e-052127231578382
Pubmed

The hypothalamic-pituitary-adrenal axis response to stress in mice lacking functional vasopressin V1b receptors.

AVPR1B CRH

1.32e-052127217122081
Pubmed

Analysis of mutation rates in the SMCY/SMCX genes shows that mammalian evolution is male driven.

KDM5C KDM5D

1.32e-05212729060413
Pubmed

Sidekicks: synaptic adhesion molecules that promote lamina-specific connectivity in the retina.

SDK2 SDK1

1.32e-052127212230981
Pubmed

Molecular basis of sidekick-mediated cell-cell adhesion and specificity.

SDK2 SDK1

1.32e-052127227644106
Pubmed

KASH protein Syne-2/Nesprin-2 and SUN proteins SUN1/2 mediate nuclear migration during mammalian retinal development.

SYNE1 SYNE2 MKI67

1.32e-0513127321177258
Pubmed

Dynamic patterns of histone H3 lysine 4 methyltransferases and demethylases during mouse preimplantation development.

SETD1A KDM5C KDM5D

1.32e-0513127324619213
Pubmed

Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.

GTPBP4 RBBP6 RCN1 THOC2 ZNF512B CBFA2T2 MDC1 MKI67 BOP1 LSM14A SNRNP70 PRRC2A ZMYM3

1.43e-058471271335850772
Pubmed

CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality.

GTPBP4 PATZ1 SPTBN1 GATAD2B ZNF512B CHD5 MDC1 YLPM1 MKI67 BOP1 SNRNP70

1.45e-056051271128977666
Pubmed

Mechanistic insights into COVID-19 by global analysis of the SARS-CoV-2 3CLpro substrate degradome.

SEPTIN9 SPTBN1 MDC1 PRRC2A

1.87e-0543127434672947
Pubmed

Comparative interactome analysis of α-arrestin families in human and Drosophila.

SETD1A RBBP6 KDM5C PTPRF NFKBIL1 NID1 GNAS DDX28

2.09e-05313127838270169
Pubmed

Identification of a novel actin isoform in hepatocellular carcinoma.

POTEF POTEE POTEI

2.10e-0515127316824795
Pubmed

Genetic Screens Reveal FEN1 and APEX2 as BRCA2 Synthetic Lethal Targets.

ORC6 NSD2 MDC1 MKI67 RHNO1 DNMT1

2.53e-05157127630686591
Pubmed

USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.

GTPBP4 SDK2 SYNE1 THOC2 OTOF MDC1 SNRNP70

2.57e-05234127736243803
Pubmed

Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains.

GTPBP4 NSD2 RCN1 THOC2 GATAD2B MDC1 NFRKB MKI67 BOP1 DNMT1

2.77e-055331271030554943
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

GTPBP4 GAK USE1 SYNE1 SPTBN1 RCN1 ZNF512B FAF2 SYNE2 PARL CIZ1 BOP1 GNAS PEAK1 EPB41L1 TP53BP1 DNMT1

3.03e-0514871271733957083
Pubmed

LINC00240 in the 6p22.1 risk locus promotes gastric cancer progression through USP10-mediated DDX21 stabilization.

MDC1 MKI67 PRRC2A

3.11e-0517127337072811
Pubmed

Examination of genetic polymorphisms in newborns for signatures of sex-specific prenatal selection.

LCT MDC1 NFKBIL1 PRRC2A TNXB

3.59e-05101127520587610
Pubmed

Integrin-linked kinase is an adaptor with essential functions during mouse development.

GDNF MKI67 NID1

3.73e-0518127319829382
Pubmed

Neonatal hyperoxia induces alterations in neurotrophin gene expression.

GDNF DNMT1

3.96e-053127226592967
Pubmed

Recruitment kinetics of DNA repair proteins Mdc1 and Rad52 but not 53BP1 depend on damage complexity.

MDC1 TP53BP1

3.96e-053127222860035
Pubmed

The inner nuclear membrane protein Sun1 mediates the anchorage of Nesprin-2 to the nuclear envelope.

SYNE1 SYNE2

3.96e-053127216079285
Pubmed

RNF168 ubiquitylates 53BP1 and controls its response to DNA double-strand breaks.

MDC1 TP53BP1

3.96e-053127224324146
Pubmed

An investigation of the neurotrophic factor genes GDNF, NGF, and NT3 in susceptibility to ADHD.

NTF3 GDNF

3.96e-053127217192954
Pubmed

Tyrosine kinase c-Abl couples RNA polymerase II transcription to DNA double-strand breaks.

MDC1 TP53BP1

3.96e-053127230668775
Pubmed

Role of ATM and the damage response mediator proteins 53BP1 and MDC1 in the maintenance of G(2)/M checkpoint arrest.

MDC1 TP53BP1

3.96e-053127220421415
Pubmed

NFBD1/MDC1, 53BP1 and BRCA1 have both redundant and unique roles in the ATM pathway.

MDC1 TP53BP1

3.96e-053127219001859
Pubmed

Expression of tenascin in developing and adult mouse lymphoid organs.

FN1 TNXB

3.96e-05312727687262
Pubmed

Mutations in the TP53 gene affected recruitment of 53BP1 protein to DNA lesions, but level of 53BP1 was stable after γ-irradiation that depleted MDC1 protein in specific TP53 mutants.

MDC1 TP53BP1

3.96e-053127228397142
Pubmed

DNA topoisomerase IIα and mitosin expression predict meningioma recurrence better than histopathological grade and MIB-1 after initial surgery.

CENPF MKI67

3.96e-053127228301542
Pubmed

Distinct versus overlapping functions of MDC1 and 53BP1 in DNA damage response and tumorigenesis.

MDC1 TP53BP1

3.96e-053127218504301
Pubmed

53BP1 and NFBD1/MDC1-Nbs1 function in parallel interacting pathways activating ataxia-telangiectasia mutated (ATM) in response to DNA damage.

MDC1 TP53BP1

3.96e-053127214695167
Pubmed

Syne-1, a dystrophin- and Klarsicht-related protein associated with synaptic nuclei at the neuromuscular junction.

SYNE1 SYNE2

3.96e-053127210878022
Pubmed

Identification of a mouse male-specific transplantation antigen, H-Y.

KDM5C KDM5D

3.96e-05312727544442
Pubmed

Altered expression of neurotrophic factors in patients with major depression.

NTF3 GDNF

3.96e-053127218313696
Pubmed

Ki-67 expression is superior to mitotic count and novel proliferation markers PHH3, MCM4 and mitosin as a prognostic factor in thick cutaneous melanoma.

CENPF MKI67

3.96e-053127220398247
Pubmed

The nesprins are giant actin-binding proteins, orthologous to Drosophila melanogaster muscle protein MSP-300.

SYNE1 SYNE2

3.96e-053127212408964
InteractionACTC1 interactions

GTPBP4 IRF2BP2 CENPF RBBP6 SEPTIN9 POTEF SYNE1 SPTBN1 NPHP4 GATAD2B POTEE MDC1 SYNE2 YLPM1 MKI67 POTEI SNRNP70 WNK2 TP53BP1

3.23e-0869412119int:ACTC1
InteractionCBX3 interactions

SETD1A FN1 RBBP6 NSD2 C9orf78 KDM5C ZNF316 FBRS ZNF512B CHD5 MDC1 UBXN7 NFRKB MKI67 ZMYM3 TP53BP1 DNMT1

3.21e-0764612117int:CBX3
InteractionSIRT7 interactions

GTPBP4 FN1 CENPF NSD2 SPTBN1 ANKHD1 THOC2 MDC1 SYNE2 YLPM1 MKI67 RBM6 BOP1 SNRNP70 PRRC2A ZMYM3 TP53BP1 DNMT1

4.79e-0774412118int:SIRT7
InteractionTERF2IP interactions

SETD1A RBBP6 NSD2 C9orf78 KDM5C THOC2 GATAD2B ZNF512B MDC1 UBXN7 NFRKB CIZ1 MKI67 ZMYM3 DNMT1

1.13e-0655212115int:TERF2IP
InteractionH3C3 interactions

GTPBP4 NSD2 C9orf78 GATAD2B ZNF512B CHD5 MDC1 NFRKB CIZ1 MKI67 BOP1 ZMYM3 DNMT1

8.88e-0649512113int:H3C3
InteractionADAR interactions

C9orf78 POTEF SPTBN1 THOC2 POTEE CHD5 MDC1 MKI67 POTEI SNRNP70

8.96e-0628612110int:ADAR
InteractionKIF20A interactions

GTPBP4 RBBP6 SYNE1 GDAP2 SPTBN1 SIPA1 THOC2 GDNF POTEE FAF2 MDC1 SYNE2 YLPM1 MKI67 BOP1 GNAS SNRNP70 PRRC2A DDX28

1.61e-05105212119int:KIF20A
InteractionTOP3B interactions

SETD1A SZT2 CENPF PPRC1 NSD2 ZNF316 FBRS RCN1 SMG5 ANKHD1 THOC2 NPHP4 PTPRF CHD5 MDC1 LSM14A MARVELD3 GNAS CABIN1 PRRC2A DDX28 WNK2 TP53BP1

1.90e-05147012123int:TOP3B
InteractionCWC22 interactions

USE1 C9orf78 THOC2 NFKBIL1 MKI67 SNRNP70 EPB41L1

2.30e-051411217int:CWC22
InteractionNUP43 interactions

SETD1A SZT2 RBBP6 NSD2 KDM5C ZNF316 MDC1 SYNE2 UBXN7 NFRKB CIZ1 MKI67 BOP1 ZMYM3

2.35e-0562512114int:NUP43
InteractionSIRT6 interactions

GTPBP4 IRF2BP2 SETD1A PATZ1 FBRS GATAD2B HPS3 MDC1 YLPM1 MKI67 RBM6 BOP1 SNRNP70 TP53BP1

2.48e-0562812114int:SIRT6
InteractionACER3 interactions

CENPF YLPM1 RBM6

3.36e-05111213int:ACER3
InteractionTERF2 interactions

CENPF ORC6 SYNE1 POTEE MDC1 SYNE2 NFRKB MKI67 SNRNP70 TP53BP1

3.95e-0534012110int:TERF2
InteractionMEN1 interactions

GTPBP4 SETD1A BATF RBBP6 THOC2 GATAD2B ZNF512B CBFA2T2 MDC1 UBXN7 YLPM1 PARL MKI67 BOP1 SNRNP70 PRRC2A ZMYM3 TP53BP1

4.20e-05102912118int:MEN1
InteractionH2BC8 interactions

NSD2 C9orf78 GATAD2B ZNF512B POTEE MDC1 UBXN7 NFRKB CIZ1 MKI67 BOP1 ZMYM3 DNMT1

4.33e-0557612113int:H2BC8
InteractionDUXA interactions

ZNF512B MDC1 MKI67

4.46e-05121213int:DUXA
InteractionCHD4 interactions

GTPBP4 SETD1A RBBP6 NSD2 PATZ1 ANKHD1 NPHP4 GATAD2B ZNF512B CHD5 MDC1 YLPM1 MKI67 BOP1 SNRNP70 ZMYM3 DNMT1

4.52e-0593812117int:CHD4
InteractionFUBP3 interactions

FN1 SMG5 RBM20 YLPM1 MKI67 RBM6 LSM14A SNRNP70 PRRC2A

7.76e-052971219int:FUBP3
InteractionSKIL interactions

FN1 CXXC5 PTPRF NID1 PAPPA SNRNP70

8.26e-051191216int:SKIL
InteractionSLFN11 interactions

CENPF RBBP6 C9orf78 POTEF KDM5C CASP9 POTEE MKI67 SNRNP70 TP53BP1

9.14e-0537612110int:SLFN11
InteractionSMC5 interactions

TCEA2 RBBP6 NSD2 SEPTIN9 THOC2 GATAD2B ZNF512B MDC1 YLPM1 NFRKB CIZ1 MKI67 RBM6 SNRNP70 PRRC2A TP53BP1 DNMT1

9.93e-05100012117int:SMC5
InteractionSIN3A interactions

IRF2BP2 NSD2 C9orf78 GATAD2B ZNF512B CBFA2T2 MDC1 CABIN1 ZMYM3 TP53BP1

9.97e-0538012110int:SIN3A
InteractionMEX3A interactions

IRF2BP2 CENPF USE1 NSD2 KDM5C SPTBN1 R3HCC1 LSM14A PRRC2A DNMT1

1.09e-0438412110int:MEX3A
InteractionLINC00240 interactions

MDC1 MKI67 PRRC2A

1.12e-04161213int:LINC00240
InteractionSNRNP40 interactions

RBBP6 NSD2 C9orf78 ZNF316 RBM20 MDC1 UBXN7 NFRKB CIZ1 MKI67 RBM6 BOP1 SNRNP70

1.20e-0463712113int:SNRNP40
InteractionASF1A interactions

IRF2BP2 CENPF THOC2 GATAD2B ZNF512B MDC1 NFRKB CABIN1

1.31e-042491218int:ASF1A
InteractionKLF10 interactions

IRF2BP2 ANKHD1 ZNF512B BOP1

1.52e-04451214int:KLF10
InteractionH3-3A interactions

SETD1A NSD2 C9orf78 KDM5C GATAD2B ZNF512B CHD5 MDC1 NFRKB MKI67 TSPYL5 CABIN1 ZMYM3 DNMT1

1.63e-0474912114int:H3-3A
InteractionADARB1 interactions

GTPBP4 NSD2 SEPTIN9 POTEF THOC2 CHD5 MDC1 MKI67 POTEI SNRNP70 TP53BP1

1.78e-0448912111int:ADARB1
InteractionACTG2 interactions

POTEF POTEE FAF2 POTEI

2.13e-04491214int:ACTG2
InteractionFXR1 interactions

TCEA2 GTPBP4 CENPF C9orf78 CAPN3 SMG5 ANKHD1 THOC2 CHRD LSM14A SNRNP70 PRRC2A TP53BP1

2.24e-0467912113int:FXR1
Cytoband16p12.2

NPIPB4 RBBP6 NPIPB3 NPIPB5

3.44e-0637127416p12.2
Cytoband16p11.2

TRIM72 SETD1A NPIPB12 NPIPB11 FBRS NPIPB13

1.63e-05191127616p11.2
CytobandEnsembl 112 genes in cytogenetic band chr16p11

TRIM72 SETD1A NPIPB12 NPIPB11 FBRS NPIPB13

1.31e-042781276chr16p11
Cytoband2q21.1

POTEF POTEE POTEI

5.71e-045812732q21.1
CytobandEnsembl 112 genes in cytogenetic band chr2q21

POTEF LCT POTEE POTEI

8.49e-041511274chr2q21
CytobandEnsembl 112 genes in cytogenetic band chr16p12

NPIPB4 RBBP6 NPIPB3 NPIPB5

1.37e-031721274chr16p12
GeneFamilyFibronectin type III domain containing

CNTN4 SDK2 FN1 PTPRF IGSF9B TNXB SDK1

4.08e-06160747555
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

CNTN4 SDK2 HMCN2 PTPRF ALPK3 IGSF9B SDK1

4.25e-06161747593
GeneFamilyAnkyrin repeat domain containing|POTE ankyrin domain containing

POTEF POTEE POTEI

1.83e-0513743685
GeneFamilySpectrin repeat containing nuclear envelope family

SYNE1 SYNE2

9.86e-0547421252
GeneFamilyImmunoglobulin like domain containing

CNTN4 SDK2 HMCN2 ALPK3 IGSF9B SDK1

1.39e-04193746594
GeneFamilyPHD finger proteins

NSD2 KDM5C KDM5D CHD5

5.06e-049074488
GeneFamilyZinc fingers CXXC-type

CXXC5 DNMT1

1.06e-0312742136
GeneFamilyUBX domain containing

FAF2 UBXN7

1.25e-0313742364
GeneFamilyAT-rich interaction domain containing

KDM5C KDM5D

1.68e-0315742418
GeneFamilyRNA binding motif containing

SETD1A PPRC1 RBM20 RBM6 SNRNP70

1.80e-03213745725
GeneFamilyAnkyrin repeat domain containing

ASPG POTEF ANKHD1 POTEE POTEI

3.14e-03242745403
GeneFamilyPHD finger proteins|Lysine demethylases

KDM5C KDM5D

4.30e-0324742485
GeneFamilyZinc fingers C2H2-type|Lysine methyltransferases|PR/SET domain family

SETD1A NSD2

8.52e-0334742487
CoexpressionGINESTIER_BREAST_CANCER_ZNF217_AMPLIFIED_DN

SETD1A SZT2 RBBP6 PPRC1 ZNF316 NPIPB3 SMG5 THOC2 NFKBIL1 SNRNP70 PRRC2A

8.19e-0733812711M17094
CoexpressionGSE3982_EOSINOPHIL_VS_MAST_CELL_UP

C9orf78 KDM5C SLA SYNE2 PITPNM3 CHRD NID1 DDX28

5.94e-061991278M5397
CoexpressionLIAO_METASTASIS

NSD2 SEPTIN9 SPTBN1 PIDD1 SMG5 HPS3 ZFP41 ALPK3 BOP1 GNAS PRRC2A ZMYM3

1.30e-0554012712M13809
CoexpressionBROWNE_HCMV_INFECTION_6HR_DN

CENPF NTF3 THOC2 AJAP1 MDC1 YLPM1 TSPYL5

1.57e-051641277M10311
ToppCellBronchial-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_pulmonary|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CNTN4 SGIP1 FN1 NTF3 RBM20 HMCN2 NID1 IGSF9B

1.01e-071971278bf0520a94ebb1d2f94de9f526d17e0b0e8fe7052
ToppCellLPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

CNTN4 FN1 SYNE1 SPTBN1 MICALL2 NID1 TNXB SDK1

1.13e-0720012789b0916d8d07ac2bf1739f7be5296bf77ffee6094
ToppCell(2)_Fibroblasts-(21)_Fibro-2|(2)_Fibroblasts / Cell class and subclass of bone marrow stroma cells in homeostatis

FN1 MATN4 JSRP1 NID1 DLX4 SDK1 EPB41L1

1.25e-061901277d2afa08ad868acc6fce308ec21b0bf93591d4010
ToppCell(2)_Fibroblasts-(21)_Fibro-2|World / Cell class and subclass of bone marrow stroma cells in homeostatis

FN1 MATN4 JSRP1 DLX4 TNXB SDK1 EPB41L1

1.29e-0619112775ee353c79055c08e8a3e2b43a0345bceb09f3890
ToppCellLPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

CNTN4 SDK2 SYNE1 MICALL2 PAPPA TNXB SDK1

1.70e-0619912778b86c69aaf60feff53aa782559cfece7342a23de
ToppCellBronchial-NucSeq-Stromal-Myofibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CNTN4 SGIP1 NTF3 RBM20 HMCN2 NID1 IGSF9B

1.76e-062001277a66449b22b39dd6987fc2c3ed160d24564234ced
ToppCellTracheal-10x5prime-Stromal-Fibroblastic-Fibro_peribronchial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

SGIP1 FN1 APCDD1 NID1 PAPPA PEAK1 TNXB

1.76e-0620012778ab0051544ea32eb8b3f7f8ba7582deaf8bf26c0
ToppCellAdult-Mesenchymal-chondrocyte|Adult / Lineage, Cell type, age group and donor

SDK2 SGIP1 FN1 NTF3 C20orf144 TNXB

6.44e-0615912763f7305ee76447064b5c846c4f576360a2f7e0b7c
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NTF3 RBM20 CHD5 IGSF9B SDK1 WNK2

1.11e-051751276d52794426f2703a80e91ae0a8ff2d8e0ce4aa4a8
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NTF3 RBM20 CHD5 IGSF9B SDK1 WNK2

1.11e-051751276454f03e6109d65f5db08dbb41ecc19ffb6bbc4e0
ToppCell5'-Adult-SmallIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FN1 HMCN2 NID1 PAPPA TNXB SDK1

1.31e-051801276f2f6e83127a4a415e65c76a35efa8175fbd5b5d9
ToppCellfacs-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l25-31|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SDK2 R3HCC1 AJAP1 MICALL2 TSPYL5 PAPPA

1.39e-051821276a1c0e4090a9e7aa4941a40c817d178de144888b6
ToppCelldroplet-Limb_Muscle-Pre-Sort-18m-Macroglial-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF316 MATN4 AJAP1 PTPRF IGSF9B WNK2

1.39e-051821276c00e503f442d44fbae73c5e2dc85be69e294e67a
ToppCelldroplet-Pancreas-Exocrine-18m-Endothelial-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FN1 CENPF MICALL2 MKI67 NID1 TNXB

1.88e-051921276a42aed9e563f5f4af029b8804c104f11ad227a8f
ToppCellhuman_hepatoblastoma-Tumor_cells-T1|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

CENPF ORC6 NSD2 MDC1 OTUD7A MKI67

1.94e-0519312764b9fa2a4424f8abe63fa7bee78db93dda04ab15f
ToppCellLV-02._Fibroblast_II|LV / Chamber and Cluster_Paper

SGIP1 FN1 APCDD1 NID1 PAPPA TNXB

1.99e-051941276014d2feb5db2a6a35ef759761a41e466e108c3c1
ToppCelldroplet-Thymus-nan-3m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CENPF ORC6 NSD2 MKI67 RHNO1 DNMT1

2.05e-0519512767ae732f100e9a3c6062be5b877efa1ec9d5b3958
ToppCellLPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

SDK2 SYNE1 MICALL2 CBFA2T2 PAPPA TNXB

2.17e-051971276fdb92985f7df0c280b87d3e43c2394e70786a2c7
ToppCellsaliva-Severe-critical_progression_d28-40-Epithelial-Epithelial,_Airway-secretory_cell|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PPRC1 RCN1 PTPRF SDK1 EPB41L1 WNK2

2.17e-051971276d6c9da7a3a6d2bcb13e2fc6605c8a59e7fb121c5
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SGIP1 APCDD1 NTF3 MICALL2 NID1 TNXB

2.17e-051971276ae0435f4b4a9cdedb1c201fc56921048390097bf
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SGIP1 APCDD1 NTF3 MICALL2 NID1 TNXB

2.17e-05197127637f6b6f2809b952382eaebb642b0aad6371f4251
ToppCellsaliva-Severe-critical_progression_d28-40-Epithelial-Epithelial,_Airway-secretory_cell-Epi-Secretory|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PPRC1 RCN1 PTPRF SDK1 EPB41L1 WNK2

2.17e-05197127680b05c8ad9c1edc5dea3236079372475431343fe
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SGIP1 FN1 NTF3 SYNE1 NID1 PEAK1

2.17e-0519712769b480f9c799a244bfee64487abd8a1bf07c9a3a2
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW13-Stem_cells|GW13 / Sample Type, Dataset, Time_group, and Cell type.

CENPF RBBP6 ANKHD1 MDC1 NFRKB NID1

2.30e-051991276fd1d1b95e01719e3d0a17d9d1f29717a47209d32
ToppCellLPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

CNTN4 SDK2 FN1 SYNE1 NID1 TNXB

2.30e-051991276a7dd94b172c973a131a6792f8ccd9bfe44d984ac
ToppCellILEUM-inflamed-(8)_Fibroblasts|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

FN1 APCDD1 NTF3 NID1 PAPPA TNXB

2.30e-0519912763a3e2bb21cd0293622b1a975263e918d9ba24265
ToppCellLPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

SDK2 FN1 SYNE1 NID1 PEAK1 TNXB

2.30e-05199127630d3e8c0681ec11f86dd38c5f48d21187a1b4f90
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW13-Stem_cells-Stem_cells|GW13 / Sample Type, Dataset, Time_group, and Cell type.

CENPF RBBP6 ANKHD1 MDC1 NFRKB NID1

2.30e-05199127691882af9dc7265c9b419f4415cbcf656087a2ab3
ToppCellBronchial-NucSeq-Stromal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SGIP1 FN1 NID1 PAPPA TNXB SDK1

2.37e-052001276389cc775c8419d90fb77cd794376d2160a7bf44e
ToppCell3'-GW_trimst-1-SmallIntestine-Mesenchymal-immature_mesenchymal_cell-cycling_stromal|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CENPF ORC6 SYNE2 MKI67 NID1 DNMT1

2.37e-052001276dd5b753bb1333fa502b9d3a6d65a53a9882b2451
ToppCellSkin-Fibroblasts|Skin / Skin and Kidney Cells in Lupus Nephritis Patients.

FN1 CHRD NID1 TNXB CCDC116 SH3BP5

2.37e-052001276f777eadf571a1a6d246da87346a9cb9d511c2e81
ToppCellBronchial-NucSeq-Stromal-Fibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SGIP1 FN1 NID1 PAPPA TNXB SDK1

2.37e-052001276cae972324d1dfea6efeaf6013f265c7c6bb48db4
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW12-OPC_related-Oligodendrocyte/OPC|GW12 / Sample Type, Dataset, Time_group, and Cell type.

PPRC1 ORC6 CBFA2T2 DCLK3 PITPNM3 NID1

2.37e-0520012764db894cfb80fd1f9e01133f345eefd78edd4bc43
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW12-OPC_related|GW12 / Sample Type, Dataset, Time_group, and Cell type.

PPRC1 ORC6 CBFA2T2 DCLK3 PITPNM3 NID1

2.37e-052001276d46a19274c2836ce7494790ce513764dedcadc79
ToppCellTracheal-NucSeq-Stromal-Fibroblastic-Fibro_peribronchial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SGIP1 APCDD1 SYNE1 NID1 PAPPA TNXB

2.37e-05200127658b38f9a484ee94191091a0659ed62ebed2d4a14
ToppCellE18.5-samps-Mesenchymal-Matrix_fibroblast-matrix_-_immature_4|E18.5-samps / Age Group, Lineage, Cell class and subclass

CENPF PIDD1 RBM20 MKI67 TNXB

3.57e-051301275169d88bffd7cd813a484d809defa638ceaca4bcb
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma-4|TCGA-Brain / Sample_Type by Project: Shred V9

TRIM72 CRH OTOF CHD5 PITPNM3

4.13e-05134127504ee54e788f6659af0349be8c0ff991fcac2b2aa
ToppCell3'_v3-blood-Lymphocytic_T_CD4-T_CD4/CD8|blood / Manually curated celltypes from each tissue

NPIPB4 SYNE1 FAM186B SYNE2 CCDC116

4.28e-051351275ae2d3a42e567b5bade304c0caa497eb725be3565
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L2/3_IT-L2/3_IT_VISp_Adamts2|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

NTF3 CAPN3 AJAP1 OTOF DCLK3

8.50e-0515612752cd007b423c2395c5ce331902e7f27c805755eb3
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L2/3_IT|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

NTF3 CAPN3 JSRP1 OTOF DCLK3

9.86e-051611275e3327c296d48e821004e61a573abb75624a6f040
ToppCellRV-13._Vascular_Smooth_Muscle|RV / Chamber and Cluster_Paper

CNTN4 SGIP1 FN1 HMCN2 MARVELD3

9.86e-05161127547b3b7662cbb671ccc086dc0a0cabd65f63eb5a1
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_T-CytoT_GZMK+-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

SYNE1 KDM5D ZFP41 SYNE2 PAPPA

1.02e-04162127519395bdb282b4a2d88cd33191af12c24a88c3d16
ToppCellAdult-Mesenchymal-chondrocyte-D231|Adult / Lineage, Cell type, age group and donor

SDK2 SGIP1 FN1 NTF3 C20orf144

1.08e-0416412752ba57dce5f69a88f0d1e450b9780425e2d9ca7d4
ToppCellfacs-Brain_Non-Myeloid-Cortex_-18m-Epithelial-neuronal_stem_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RCN1 MATN4 SSC4D IGSF9B CCDC40

1.08e-0416412750853e75b60b2a78257b660910c3ee15b09c5f5b0
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CENPF ORC6 NSD2 MKI67 DCLK3

1.14e-0416612752642544070564debe2deb2938d2c33997bf5ef02
ToppCellfacs-Large_Intestine-Distal-18m-Epithelial-epithelial_cell_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CENPF MATN4 NPHP4 MKI67 DNMT1

1.38e-041731275a5172dee859bf6c2eed46c48bd64dfef0ff9f28f
ToppCellfacs-Large_Intestine-Distal-18m-Epithelial-Lgr5-_amplifying_undifferentiated_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CENPF MATN4 NPHP4 MKI67 DNMT1

1.38e-041731275639b5b0b33ce5aa0bc26363c059717012ddc14c0
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_prolif|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ORC6 NSD2 LCT MKI67 DNMT1

1.42e-041741275c988471207ba06195bc3e41056435e8c31c20bbe
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SDK2 GPR61 YLPM1 PITPNM3 IGSF9B

1.42e-041741275f1fe1f4216748a9562dd03bd48c70b23c7ff4d1d
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_G2M|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

APCDD1 CENPF NTF3 NPHP4 CRH

1.42e-0417412757fb7bdf62563f2102fb38618b503eb2817b6594f
ToppCell5'-Adult-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HMCN2 NID1 PAPPA SH3BP5 CCDC40

1.54e-041771275bd602db857f37869ef76d14c05ef522c509f08ee
ToppCellPND03-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CENPF ORC6 NSD2 MKI67 DNMT1

1.54e-0417712758a74f5e72de605774111057bd87a7e7e4a6385cd
ToppCell368C-Myeloid-Macrophage-SPP1+_Macrophage_3|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

NPIPB11 NPHP4 MICALL2 UBXN7 DDX28

1.58e-0417812759d575902d3dbe33437c9d4200df093a741269803
ToppCell368C-Myeloid-Macrophage-SPP1+_Macrophage_3|368C / Donor, Lineage, Cell class and subclass (all cells)

NPIPB11 NPHP4 SLA UBXN7 DDX28

1.58e-041781275536a601abcc60867949ea06e9aafb6c7b799b56b
ToppCellPND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_G2M|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

APCDD1 CENPF MKI67 TNXB SDK1

1.58e-041781275c77a1d1a9aef0ab51b4408b9e84f201219788ca2
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Rectal_Adenocarcinoma|TCGA-Colorectal / Sample_Type by Project: Shred V9

TCEA2 IRF2BP2 ZNF316 SMG5 ZFP41

1.66e-041801275c3d1521ac90f2e3fc31158e6e61907e05c37af39
ToppCelldroplet-Heart-nan-3m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SGIP1 PATZ1 MATN4 HPS3 PAPPA

1.66e-041801275da723df348d7b8449bb1124f23fe6fa706412adb
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MATN4 GDNF AJAP1 CHD5 PAPPA

1.66e-041801275d9c9399df3e2d9f23dbbfffb6cbe8404bf01e2b7
ToppCell5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_pulmonary-EC_venous_pulmonary_L.2.2.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CENPF PIDD1 MKI67 NID1 TNXB

1.66e-04180127540d4838a0ccb10d5e49266bc8a0037d27b75ccc2
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Neuronal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MATN4 GDNF AJAP1 CHD5 PAPPA

1.66e-041801275dad458398683ff80a6e207bdc08e257d1bb757d6
ToppCellControl-Fibroblasts-Airway_smooth_muscle|Control / group, cell type (main and fine annotations)

SGIP1 FN1 NTF3 RBM20 IGSF9B

1.66e-041801275d0de12749ef0f51f0931c6e7b9b99966bdbc3ec1
ToppCelldroplet-Heart-nan-3m-Neuronal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SGIP1 PATZ1 MATN4 HPS3 PAPPA

1.66e-0418012755b146a94708b3c3610542a4d0925f3f7a2b19185
ToppCelldroplet-Heart-nan-3m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SGIP1 PATZ1 MATN4 HPS3 PAPPA

1.66e-04180127550758b1e7be2e43f83c10ab106900c067e61f5f7
ToppCell368C-Lymphocytic-CD4_T-cell-Treg_cell_3|368C / Donor, Lineage, Cell class and subclass (all cells)

LMF1 BATF ZNF512B SYNE2 DDX28

1.70e-041811275b193f3606554adc55c5906219d114288bb1f978a
ToppCelldroplet-Thymus-nan-24m-Lymphocytic-DN3_thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LMF1 RCN1 MON1A KDM5D CCDC40

1.70e-041811275e2d03115a87f45a7ddd3ade6b9ac3843639bd41a
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c11-GNLY|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SYNE1 R3HCC1 SIPA1 NPIPB13 SYNE2

1.70e-0418112755cecbafc29cc95896e6ccb2c74d9237b9aaece69
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SDK2 SGIP1 FN1 CHRD TNXB

1.70e-041811275b116c68393d8836bac080f81a8fcbeb52e0403e7
ToppCelldroplet-Thymus-nan-24m-Lymphocytic-Double_negative_thymocyte,_DN3_(Cd8-,_Cd4-),_some_express_pre_TCR_alpha|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LMF1 RCN1 MON1A KDM5D CCDC40

1.70e-041811275d8d11ef83c4b8b6a6f5c8728e03059e45a8ad264
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MATN4 GDNF AJAP1 CHD5 PAPPA

1.75e-041821275812ff2a50a510b18d865e89465dba1754a08ef61
ToppCelldroplet-Heart-4Chambers-18m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MATN4 PTPRF CHD5 MKI67 PAPPA

1.75e-0418212756fdaf3c8c3952a8f14dd7288e523ed58eb1d3517
ToppCellRA-13._Vascular_Smooth_Muscle|RA / Chamber and Cluster_Paper

CNTN4 FN1 NTF3 HMCN2 SDK1

1.79e-041831275818fd886e0188091310825f9145fa53328f2c979
ToppCellRA-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

CNTN4 FN1 NTF3 HMCN2 SDK1

1.79e-041831275cae2ee08f985a6f005b4b8e959e465350315156a
ToppCellControl-immature_Neutrophil-|Control / Disease condition and Cell class

SETD1A CENPF NSD2 MKI67 RHNO1

1.84e-041841275c4e8ba82a6aa76c46f05a71d5f1c7926555318cf
ToppCellControl-immature_Neutrophil|Control / Disease condition and Cell class

SETD1A CENPF NSD2 MKI67 RHNO1

1.84e-0418412752fdae5c6b3eb2232881d933a8c1061fda3623016
ToppCell3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_T/NK-T_cell-T_cells_proliferating-T_cells_proliferating_L.1.1.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CENPF ORC6 NSD2 MKI67 DNMT1

1.84e-0418412758260e688ec42a1374727bc85dceb7edd19a8b662
ToppCellCOVID-19-Heart-Fib_2|COVID-19 / Disease (COVID-19 only), tissue and cell type

FN1 APCDD1 HMCN2 NID1 TNXB

1.89e-0418512758f95d8e591bf7379d13f5a0545b0cb49e2b1ab5d
ToppCelldroplet-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l20-1|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SPTBN1 CHRD NID1 TNXB SDK1

1.89e-041851275d5f5866924648a3c14e2596218fd548a31777aa3
ToppCell3'-GW_trimst-1-LargeIntestine-Mesenchymal-Pericytes-Immature_pericyte|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

APCDD1 SEPTIN9 DCLK3 NID1 PEAK1

1.93e-041861275db4d9ac89cc1e55062ba888b3410b773340595dd
ToppCellLA-01._Fibroblast_I|World / Chamber and Cluster_Paper

FN1 APCDD1 HMCN2 NID1 TNXB

1.98e-0418712754ea486991f66c29728d127171a07b81404ec0b78
ToppCellControl-Fibroblasts-Alveolar_FB|Control / group, cell type (main and fine annotations)

SGIP1 FN1 NID1 TNXB SDK1

1.98e-04187127592d468dde81125d51daf7abd4703741abe1ab91c
ToppCellfacs-Heart-LA-18m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GDAP2 GDNF ZNF512B PTPRF EPB41L1

1.98e-041871275f1e9877d859369b862d4a559ec9ab9be74a67a96
ToppCellfacs-Heart-LA-18m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GDAP2 GDNF ZNF512B PTPRF EPB41L1

1.98e-0418712753ffbd50b49059dcd3e23c5ac01901e4352142446
ToppCelldroplet-Marrow-nan-3m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SYNE1 SPTBN1 SYNE2 MKI67 DNMT1

1.98e-04187127514c239af77116d28d511dea754b6150d20488080
ToppCellfacs-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l20-1|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FN1 CHRD NID1 TNXB SDK1

2.03e-041881275aa516273cdde53c8c0295f06830972388f890c97
ToppCellLA-13._Vascular_Smooth_Muscle|LA / Chamber and Cluster_Paper

CNTN4 FN1 NTF3 HMCN2 SDK1

2.03e-04188127534e1b074a3995aa46ab194eb45115d76d1a5514d
ToppCellSmart-seq2-bone_marrow_(Smart-seq2)|Smart-seq2 / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

CENPF SYNE1 KDM5D JSRP1 MKI67

2.03e-041881275557a0ac069a6ff4e687cac032f64170b9b247165
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NTF3 GDNF CHD5 SDK1 WNK2

2.08e-0418912757fbe855bfdb47d35e040b04a80fe4b729a3764e8
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NTF3 GDNF CHD5 SDK1 WNK2

2.08e-04189127506b35abecd29f902cf251fcc1f6ad33db7ab08a2
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NTF3 RBM20 IGSF9B SDK1 WNK2

2.08e-041891275127ad2ba3e794df8cce2eee3e4171bccb5aad51b
ToppCellLA-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

CNTN4 FN1 NTF3 HMCN2 SDK1

2.08e-0418912756b3e88751b95fc2173f2c3d5061ed632d0c5f01c
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NTF3 RBM20 IGSF9B SDK1 WNK2

2.08e-0418912752cfb4d12f75678d1619f4743838a0e954bd57761
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SGIP1 SYNE1 FAM186B NID1 PEAK1

2.14e-0419012751121eb607a984c59fbffe7220837fc178745aa55
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SGIP1 SYNE1 FAM186B NID1 PEAK1

2.14e-041901275048b581e3f7ea9fc2f87c0532974bba85c7292c2
ToppCelldroplet-Spleen-nan-18m-Lymphocytic-immature_NKT_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CENPF NSD2 RBM20 MKI67 DNMT1

2.14e-041901275b99271d139c8d01e20feb95d99f79c9b2756b4cb
ToppCellkidney_cells-Adult_normal_reference-Immune-Lymphocytic_T/NK-Cycling_Natural_Killer_Cell_/_Natural_Killer_T_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CENPF BATF ORC6 MKI67 DNMT1

2.14e-041901275b65383e256b04122500b742caeed0b807793851e
ToppCellControl-Fibroblasts|Control / group, cell type (main and fine annotations)

SGIP1 FN1 NID1 TNXB SDK1

2.14e-0419012753a42a9b98d954685d38a741f44545898d0e3e9ce
ToppCellkidney_cells-Adult_normal_reference-Immune-Lymphocytic_T/NK-Cycling_Natural_Killer_Cell_/_Natural_Killer_T_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CENPF BATF ORC6 MKI67 DNMT1

2.14e-04190127589095d3e023269d89c82e3a73550f869e3f34201
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SDK2 SGIP1 FN1 PAPPA SDK1

2.19e-04191127508720998aa55131d7377c4c67c4c935865bd7d79
ToppCell(11)_FOXN4+-(0)_Reference|(11)_FOXN4+ / shred by cell type by condition

TRIM72 USE1 POTEF MDC1 MAN1B1

2.24e-041921275ef06f96b934dd05b40025f8215b6d919d3a17045
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_myocytic-mes_pericyte_(14)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

CNTN4 RBM20 DCLK3 CHRD PAPPA

2.24e-04192127555f95454399fd533df75db06584eaa48d6ee3830
DrugPentylenetetrazole [54-95-5]; Down 200; 29uM; HL60; HG-U133A

GAK RBBP6 PATZ1 R3HCC1 ZNF512B FAF2 NFRKB CIZ1 PRRC2A

1.20e-0619412491408_DN
Drug0175029-0000 [211245-78-2]; Down 200; 1uM; PC3; HT_HG-U133A

LMF1 CENPF USE1 SYNE1 PIDD1 SMG5 CIZ1 SH3BP5

9.42e-0618912487392_DN
DrugLY 294002; Down 200; 0.1uM; HL60; HT_HG-U133A

KDM5C CAPN3 FBRS SMG5 SIPA1 CBFA2T2 NFRKB LSM14A

1.27e-0519712481157_DN
Drug2f3r

PPRC1 LCT PRRC2A

1.29e-0591243CID006852180
DrugDropropizine (R,S) [17692-31-8]; Down 200; 17uM; HL60; HT_HG-U133A

CENPF PATZ1 CAPN3 SMG5 DLX4 PRRC2A MAN1B1 SH3BP5

1.32e-0519812482398_DN
DrugXamoterol hemifumarate [73210-73-8]; Down 200; 5uM; MCF7; HT_HG-U133A

SETD1A LMF1 SPTBN1 FBRS SMG5 MICALL2 CBFA2T2 CABIN1

1.37e-0519912485363_DN
DrugNorcyclobenzaprine [303-50-4]; Down 200; 15.4uM; MCF7; HT_HG-U133A

GAK CENPF NSD2 PATZ1 SPTBN1 NPHP4 CIZ1 EPB41L1

1.37e-0519912482830_DN
Diseasesyndromic X-linked intellectual disability Claes-Jensen type (implicated_via_orthology)

KDM5C KDM5D

8.99e-0541152DOID:0060809 (implicated_via_orthology)
DiseaseAutosomal dominant Emery-Dreifuss muscular dystrophy

SYNE1 SYNE2

8.99e-0541152cv:CN293514
DiseaseAutosomal Recessive Emery-Dreifuss Muscular Dystrophy

SYNE1 SYNE2

1.49e-0451152C1450051
DiseaseAutosomal Dominant Emery-Dreifuss Muscular Dystrophy (disorder)

SYNE1 SYNE2

1.49e-0451152C0410190
Diseaseage at menopause

SGIP1 APCDD1 NPIPB2 FAF2 NFKBIL1 PARL PRRC2A

1.87e-043021157EFO_0004704
Diseaseintellectual disability (implicated_via_orthology)

KDM5C CAPN3 KDM5D GATAD2B

2.15e-04751154DOID:1059 (implicated_via_orthology)
DiseaseEmery-Dreifuss muscular dystrophy

SYNE1 SYNE2

2.24e-0461152cv:C0410189
DiseaseMuscular Dystrophy, Emery-Dreifuss

SYNE1 SYNE2

2.24e-0461152C0410189
Diseasepsoriatic arthritis, psoriasis

CNTN4 APCDD1

2.24e-0461152EFO_0000676, EFO_0003778
Diseaseelectrocardiography

LMF1 SGIP1 POTEF SPTBN1 JSRP1 RBM20 HMCN2 RBM6 PROB1

2.37e-045301159EFO_0004327
DiseaseX-Linked Emery-Dreifuss Muscular Dystrophy

SYNE1 SYNE2

3.12e-0471152C0751337
Diseasemetabolite measurement

SETD1A ASPG CASP9 AJAP1 SYNE2 YLPM1 MARVELD3 CABIN1 DHTKD1

3.55e-045601159EFO_0004725
DiseaseMitral valve prolapse

SPTBN1 RBM20 ALPK3

3.75e-04361153HP_0001634
Diseasetriglyceride measurement, low density lipoprotein cholesterol measurement

TCEA2 LMF1 CAPN3 SYNE2 TP53BP1

4.95e-041661155EFO_0004530, EFO_0004611
DiseaseIGF-1 measurement

TRIM72 TCEA2 LMF1 CAPN3 ZNF316 SYNE2 GNAS DNMT1

6.67e-044881158EFO_0004627
Diseasegastroesophageal reflux disease

MON1A YLPM1 RBM6 SDK1

6.68e-041011154EFO_0003948
Diseasemean arterial pressure

SGIP1 SZT2 SEPTIN9 SIPA1 GDNF GNAS SNRNP70 DNMT1

7.71e-044991158EFO_0006340
Diseasetriglyceride measurement, intermediate density lipoprotein measurement

LMF1 CAPN3 SYNE2 TP53BP1

9.51e-041111154EFO_0004530, EFO_0008595
DiseaseEmery-Dreifuss muscular dystrophy (implicated_via_orthology)

SYNE1 SYNE2

9.69e-04121152DOID:11726 (implicated_via_orthology)
Diseasehyperinsulinism (is_implicated_in)

PTPRF PARL

9.69e-04121152DOID:2018 (is_implicated_in)
Diseasesugar consumption measurement

CNTN4 GDNF PTPRF IGSF9B

1.27e-031201154EFO_0010158
Diseasesexual dimorphism measurement

R3HCC1 CXXC5 MON1A SIPA1 GDNF CBFA2T2 ZFP41 ALPK3 RBM6 PAPPA EPB41L1 TP53BP1

1.29e-03110611512EFO_0021796
Disease1-methylurate measurement

CNTN4 PTPRF

1.33e-03141152EFO_0021173
DiseaseColorectal Carcinoma

CNTN4 FN1 SYNE1 RCN1 HPS3 CHD5 MKI67 NID1 GNAS

1.74e-037021159C0009402
Diseasesyndromic intellectual disability (implicated_via_orthology)

KDM5C KDM5D

1.74e-03161152DOID:0050888 (implicated_via_orthology)
Diseaseautism spectrum disorder, schizophrenia

CNTN4 PTPRF ALPK3 IGSF9B PRRC2A TNXB

1.81e-033271156EFO_0003756, MONDO_0005090
Diseasetriglyceride measurement, very low density lipoprotein cholesterol measurement

TCEA2 LMF1 CAPN3 SYNE2 TP53BP1

1.88e-032241155EFO_0004530, EFO_0008317
DiseaseIntellectual Disability

SETD1A NSD2 SYNE1 KDM5C GNAS EPB41L1 MAN1B1

1.88e-034471157C3714756
Diseasemuscular dystrophy (is_implicated_in)

SYNE1 CAPN3

1.97e-03171152DOID:9884 (is_implicated_in)
Diseasesphingomyelin 14:0 measurement

SYNE2 NID1

1.97e-03171152EFO_0010390
DiseaseGrand Mal Status Epilepticus

NTF3 GDNF CRH

2.30e-03671153C0311335
DiseaseStatus Epilepticus, Subclinical

NTF3 GDNF CRH

2.30e-03671153C0751522
DiseaseSimple Partial Status Epilepticus

NTF3 GDNF CRH

2.30e-03671153C0751524
DiseaseNon-Convulsive Status Epilepticus

NTF3 GDNF CRH

2.30e-03671153C0751523
DiseasePetit mal status

NTF3 GDNF CRH

2.30e-03671153C0270823
DiseaseComplex Partial Status Epilepticus

NTF3 GDNF CRH

2.30e-03671153C0393734
DiseaseMHC class I polypeptide-related sequence A measurement

NFKBIL1 PRRC2A TNXB

2.40e-03681153EFO_0008233
DiseaseStatus Epilepticus

NTF3 GDNF CRH

2.40e-03681153C0038220
DiseaseChronic myeloproliferative disorder

CENPF ORC6

2.47e-03191152C1292778
Diseasereticulocyte count

USE1 PATZ1 SEPTIN9 POTEF SIPA1 NPIPB2 SYNE2 NFKBIL1 NFRKB LSM14A DNMT1

2.60e-03104511511EFO_0007986
DiseaseConventional (Clear Cell) Renal Cell Carcinoma

KDM5C PIDD1 SYNE2 DCLK3

2.73e-031481154C0279702
Diseasereticulocyte measurement

USE1 PATZ1 SEPTIN9 POTEF SIPA1 NPIPB2 SYNE2 NFKBIL1 RBM6 LSM14A DNMT1

2.75e-03105311511EFO_0010700
Diseasekidney disease (biomarker_via_orthology)

CASP9 MKI67

3.01e-03211152DOID:557 (biomarker_via_orthology)
DiseaseMalignant neoplasm of breast

FN1 CENPF NSD2 SYNE1 OTOF CHD5 SYNE2 MKI67 PRRC2A TP53BP1 DNMT1

3.20e-03107411511C0006142
DiseaseSeckel syndrome

CENPF ORC6

3.31e-03221152C0265202
DiseaseAlzheimer's disease (is_marker_for)

CASP9 GDNF CRH GNAS SNRNP70

3.40e-032571155DOID:10652 (is_marker_for)
DiseaseGlioblastoma

FN1 GDNF TP53BP1

3.68e-03791153C0017636
Diseasealcohol consumption measurement, high density lipoprotein cholesterol measurement

CAPN3 ZFP41 RBM6 TP53BP1

3.77e-031621154EFO_0004612, EFO_0007878

Protein segments in the cluster

PeptideGeneStartEntry
AAPSVRPEKRRSEPE

BOP1

11

Q14137
RPEKRRSEPELEPEP

BOP1

16

Q14137
SEPRPGEQEPIFRKR

CCDC116

256

Q8IYX3
RAREERPEETEKAPP

CHD5

1616

Q8TDI0
PLPAEEPERAKSGTR

DNMT1

216

P26358
KRSRSEEPAEILPPA

SH3BP5

6

O60239
HLAIPTRRDDKERPP

GTPBP4

361

Q9BZE4
TRRDDKERPPFIPEG

GTPBP4

366

Q9BZE4
KERPPFIPEGVVARR

GTPBP4

371

Q9BZE4
EERESPTVSPRGPRK

ALPK3

1386

Q96L96
DPRRRIPGGVSTTEP

AJAP1

241

Q9UKB5
GIGEPSRPSEKRRTE

CNTN4

681

Q8IWV2
VDSPGPSERETLPRK

FAM186B

336

Q8IYM0
RKPESREPQGALERP

DHTKD1

36

Q96HY7
SEKPRLSPEPSERRP

DLX4

96

Q92988
PKRRRAADVEPSSPE

NPIPB3

971

Q92617
AADVEPSSPEPKRRR

NPIPB3

976

Q92617
PSSPEPKRRRVGDVE

NPIPB3

981

Q92617
KRRRAADVEPSSPEP

NPIPB3

1001

Q92617
ADVEPSSPEPKRRRV

NPIPB3

1006

Q92617
SSPEPKRRRVGDVEP

NPIPB3

1011

Q92617
RRRAADVEPSLPEPK

NPIPB3

1031

Q92617
VLKREAPAGRDPEEP

R3HCC1

156

Q9Y3T6
ERVVRPDSELGERPP

RCN1

36

Q15293
PRPEDSGIVPRFERK

RBM20

1211

Q5T481
RRRAADVEPSSPEPK

NPIPB12

851

F8W0I5
DVEPSSPEPKRRRVG

NPIPB12

856

F8W0I5
SPEPKRRRVGDVEPS

NPIPB12

861

F8W0I5
RRAADVEPSSPEPKR

NPIPB12

881

F8W0I5
VEPSSPEPKRRRVGD

NPIPB12

886

F8W0I5
PEPKRRRVGDVEPSR

NPIPB12

891

F8W0I5
RAADVEPSLPEPKRR

NPIPB12

911

F8W0I5
PERQIRISEKPGAPE

GDAP2

251

Q9NXN4
DDGLIPPRKSRTPES

POTEF

566

A5A3E0
REGSEEKVKPPRPRA

EPB41L1

561

Q9H4G0
KPAPEEELRLPSREG

GPR61

361

Q9BZJ8
SVAEGARPPEERVPR

MATN4

126

O95460
IPKETAERVGPERGP

MDC1

816

Q14676
PRAEAEVRPKIPGSR

JSRP1

191

Q96MG2
RQKRPSPSRTPEERE

NFRKB

171

Q6P4R8
LRGEMTPPSVEERRP

ASPG

356

Q86U10
KDRVPLDPRSPRFEI

HMCN2

3721

Q8NDA2
RRAKRLQPDPEPTEE

KDM5D

211

Q9BY66
KTRPEENKPERPSGR

DCLK3

326

Q9C098
RLAPTPTEGKVRPRV

MICALL2

326

Q8IY33
FDRDTIAPEPPAKRV

CBFA2T2

246

O43439
DSLERPLRKERPVPS

PEAK1

1216

Q9H792
RAATERPLGPPTERT

NID1

336

P14543
PDVSSEEEGPAPRRR

FAM214B

251

Q7L5A3
REARETQESERKPPP

NSD2

976

O96028
RRGLTVRSPDEPLPV

DDX28

21

Q9NUL7
PKSPGVPRDVEAADR

LCT

1131

P09848
TEDRPTDRPIPPRDE

LSM14A

46

Q8ND56
RRRAADVEPSSPEPK

NPIPB5

1056

A8MRT5
DVEPSSPEPKRRRVG

NPIPB5

1061

A8MRT5
SPEPKRRRVGDVEPS

NPIPB5

1066

A8MRT5
RRAADVEPSSPEPKR

NPIPB5

1086

A8MRT5
VEPSSPEPKRRRVGD

NPIPB5

1091

A8MRT5
PEPKRRRVGDVEPSR

NPIPB5

1096

A8MRT5
RAADVEPSLPEPKRR

NPIPB5

1116

A8MRT5
KRPPEAPAEDRSLGR

GDNF

26

P39905
PVEEEPSRRRPRAPK

MKI67

2656

P46013
RSEPERGRLTPSPDI

GATAD2B

111

Q8WXI9
RRPETEGVPVPERAS

OTUD7A

696

Q8TE49
DREPKPTRAGPREEH

NFKBIL1

271

Q9UBC1
REARGATEEPSPPSR

PAPPA

81

Q13219
EAPERERRSEEPPIS

CRH

146

P06850
RRRAADVEPSSPEPK

NPIPB4

1061

C9JG80
DVEPSSPEPKRRRVG

NPIPB4

1066

C9JG80
SPEPKRRRVGDVEPS

NPIPB4

1071

C9JG80
RRAADVEPSSPEPKR

NPIPB4

1091

C9JG80
VEPSSPEPKRRRVGD

NPIPB4

1096

C9JG80
PEPKRRRVGDVEPSR

NPIPB4

1101

C9JG80
RAADVEPSLPEPKRR

NPIPB4

1121

C9JG80
STLPKAEAPREPERG

NTF3

61

P20783
DDTPPPERRNKSGII

CXXC5

51

Q7LFL8
TKRQEAPVDPRPEGD

MAN1B1

186

Q9UKM7
DAPTEPVSGPKVERR

NPHP4

456

O75161
DGERERSPRSEPPIK

RBBP6

1046

Q7Z6E9
PKRRRAADVEPSSPE

NPIPB11

1111

E5RHQ5
AADVEPSSPEPKRRR

NPIPB11

1116

E5RHQ5
PSSPEPKRRRVGDVE

NPIPB11

1121

E5RHQ5
KRRRAADVEPSSPEP

NPIPB11

1141

E5RHQ5
ADVEPSSPEPKRRRL

NPIPB11

1146

E5RHQ5
LPISEDPDGPRKRSR

PATZ1

336

Q9HBE1
DDGLIPPRKSRTPES

POTEE

566

Q6S8J3
REAVPSGRPRPDTLT

MON1A

56

Q86VX9
EVEVEPRDRPSREAP

GAK

706

O14976
PEAARTPGSDKERPV

FBRS

241

Q9HAH7
TPGSDKERPVERREP

FBRS

246

Q9HAH7
ERKDKESPRAGPTEP

CABIN1

1746

Q9Y6J0
PERSPTDSPREGLRV

CENPF

3076

P49454
IESRVGRKPPEEPAN

C16orf96

1126

A6NNT2
REVVPRPRPGVTEAT

FN1

2036

P02751
PPPGKQDSSDDVRRV

BATF

16

Q16520
RKPEVLRPETPRPVD

CASP9

116

P55211
TGPPESRERRVTSPE

CCDC40

146

Q4G0X9
QRPSDGSSPDRPEKR

APCDD1

441

Q8J025
APREAGPAEEQPRKR

C20orf144

131

Q9BQM9
ERYLPSTPRPGREEV

MARVELD3

161

Q96A59
PRGSDERPTRTIIPV

CAPN3

306

P20807
ERTKDDAPGPPVRLV

SDK1

1371

Q7Z5N4
VVTTEKRDRPQPPSR

SDK2

1391

Q58EX2
ARTARKRKPSPEPEG

IRF2BP2

351

Q7Z5L9
RSAKPVRSEPELPVE

PPP4R1L

321

Q9P1A2
VDPVLVKSRPTDPRR

PPRC1

681

Q5VV67
QRPRPRKEPGDEEEV

OTOF

651

Q9HC10
VKVIFPPGATEEPRR

PIDD1

476

Q9HB75
DVEPSSPKPKRRRVG

NPIPB13

1066

A6NJU9
SPKPKRRRVGDVEPS

NPIPB13

1071

A6NJU9
RRAADVEPSSPEPKR

NPIPB13

1091

A6NJU9
VEPSSPEPKRRRVGD

NPIPB13

1096

A6NJU9
PEPKRRRVGDVEPSR

NPIPB13

1101

A6NJU9
RAADVEPSSPEPKRR

NPIPB13

1121

A6NJU9
VRTDEDVPSGPPRKV

PTPRF

701

P10586
APRKVEPRRSDPGTS

PARL

56

Q9H300
PDISPPIFRRGEKLR

SLA

36

Q13239
PRDAPPPTRAETREE

SNRNP70

51

P08621
PPSSRREDEGPRDTV

SZT2

1461

Q5T011
RPADKEPEPRKREEG

RBM6

596

P78332
PSESEKDVSRRPLVP

RHNO1

116

Q9BSD3
AKRLRLEEPAGPEPR

PRR23A

26

A6NEV1
EEGTRSPTLEPPRGR

SMG5

531

Q9UPR3
VKLPVRDPVRDTPGT

SYNE1

1086

Q8NF91
GGLEPRVEKTRPEPT

SYNE2

4221

Q8WXH0
AEPEAIPERRQSPKR

HPS3

451

Q969F9
GAPDKRERAERPPVE

GNAS

341

Q5JWF2
SPRVSQGRKPRDPES

PRORY

11

Q9H606
AKRLRLEEPAGPEPR

PRR23B

26

Q6ZRT6
IRPDPRSRVTDPVGD

FAF2

121

Q96CS3
TSERRGDKEAPPPVL

PRRC2A

1331

P48634
EVLGHKTPEPAPRRT

SEPTIN9

136

Q9UHD8
VTVLPPDESGRPRRS

SIPA1

756

Q96FS4
VDREPGDVATPPRKR

ORC6

186

Q9Y5N6
DDGLIPPRKSRTPES

POTEI

566

P0CG38
RAIRRDKPAPGTEPL

PROB1

321

E7EW31
PEREEVRTSPRPASP

SETD1A

451

O15047
QEEEERKRRPPSPEP

SPTBN1

2091

Q01082
DRKIPPPIGTERLAR

ANKHD1

2361

Q8IWZ3
RRPAPETRTDPELEK

CHRD

936

Q9H2X0
RLRSSEEPTEKEPPG

CIZ1

261

Q9ULV3
ASGAREKRPEEPRPL

ZNF837

21

Q96EG3
EPRPLEEDRAGSRPT

ZNF837

31

Q96EG3
APGRVPTTARERVPA

USE1

91

Q9NZ43
TLSGRPRPEESPRDL

AVPR1B

396

P47901
REEKVSGDRKPPERP

ZFP41

26

Q8N8Y5
PRSDIPEPEREQKRR

THOC2

1396

Q8NI27
SPRRTGEELLRPETP

IGSF9B

1306

Q9UPX0
DGSETTRVPTPRPRD

SSC4D

456

Q8WTU2
EEVARPRRSTPTPEL

SGIP1

171

Q9BQI5
ADGTTAPERKEEPPR

TNXB

1241

P22105
PDDKSFSRVVPRVPD

TP53BP1

1431

Q12888
EAKEPRALRSPERRP

TRIM72

396

Q6ZMU5
EPKRRRAAEVESPPE

NPIPB2

351

A6NJ64
RAAEVESPPEPKRRR

NPIPB2

356

A6NJ64
ESPPEPKRRRAAEVE

NPIPB2

361

A6NJ64
PKRRRAAEVEPSSPE

NPIPB2

366

A6NJ64
AAEVEPSSPEPKRRR

NPIPB2

371

A6NJ64
SSGLEDEEPKRPLPR

PITPNM3

326

Q9BZ71
DILKPPGRESRPERI

YLPM1

1821

P49750
RTPEEPVAKLPPRRD

ZNF512B

851

Q96KM6
PSGKVDPAPERRFLE

ZNF316

566

A6NFI3
GHRKEENRRPLTEPP

UBXN7

356

O94888
RDASEAPDPSRKRPE

TCEA2

101

Q15560
RPLRVGDTEKPEPER

C9orf78

246

Q9NZ63
AKPEPGRTRRDEPEE

WNK2

161

Q9Y3S1
ERVRRAEPPKPEVVD

ZMYM3

241

Q14202
AKARVRPAPDDAPRD

TSPYL5

21

Q86VY4
RRAKRLQPDPEPTEE

KDM5C

211

P41229
RRRKTGYSDPEPESP

LMF1

16

Q96S06