Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionprotein tyrosine phosphatase activity

DUSP4 PTPN18 PTPRT PTPRD PTPRS CDC25B CDC25C

5.42e-051031887GO:0004725
GeneOntologyMolecularFunctionhydrolase activity, acting on ester bonds

PLA2G7 INPP4A PPP1R3E DUSP4 OCRL PDE10A PTPN18 DICER1 PTPRT BPNT1 DFFB PTPRD PTPRS HELZ2 PLA2G4F PLCH1 CDC25B CDC25C DNASE1 PIWIL3

7.84e-0580718820GO:0016788
GeneOntologyMolecularFunctionphosphoric ester hydrolase activity

INPP4A PPP1R3E DUSP4 OCRL PDE10A PTPN18 PTPRT BPNT1 PTPRD PTPRS PLCH1 CDC25B CDC25C

7.86e-0538618813GO:0042578
GeneOntologyMolecularFunctionphosphatase activity

INPP4A PPP1R3E DUSP4 OCRL PTPN18 PTPRT BPNT1 PTPRD PTPRS CDC25B CDC25C

9.10e-0528718811GO:0016791
GeneOntologyMolecularFunctionintramolecular phosphotransferase activity

PGAM1 PGM5 PGAM4

1.28e-04111883GO:0016868
GeneOntologyMolecularFunctionphosphoprotein phosphatase activity

PPP1R3E DUSP4 PTPN18 PTPRT PTPRD PTPRS CDC25B CDC25C

4.34e-041891888GO:0004721
GeneOntologyMolecularFunctionbisphosphoglycerate mutase activity

PGAM1 PGAM4

5.23e-0441882GO:0004082
GeneOntologyMolecularFunction2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity

PGAM1 PGAM4

5.23e-0441882GO:0046538
GeneOntologyMolecularFunctionphosphoglycerate mutase activity

PGAM1 PGAM4

5.23e-0441882GO:0004619
GeneOntologyMolecularFunctionlamin binding

LBR SUN2 PKP1

7.12e-04191883GO:0005521
GeneOntologyMolecularFunctionATP-dependent activity

MCM8 DNAH10 ABCC11 MCM7 ATP9A DICER1 DHX30 DNAH17 HELZ2 ERCC6L2 ABCD4 UBA6 KIF13A TAP1 ATP4A

7.31e-0461418815GO:0140657
GeneOntologyMolecularFunctioninositol phosphate phosphatase activity

INPP4A OCRL BPNT1

8.32e-04201883GO:0052745
GeneOntologyMolecularFunctiondeoxyribonuclease I activity

DICER1 DNASE1

8.65e-0451882GO:0004530
GeneOntologyBiologicalProcesscell junction organization

UNC13B FNTA ADGRB2 DOCK10 CRTAC1 ACTN1 ITGA3 PIP5K1C PTPRT SVEP1 CACNG2 RHOG GRHL1 SLC9A1 HEG1 PTPRD PTPRS PAFAH1B1 PLEC RIMS2 PCDHGC3 PLXNB1 PHLDB2 CDH17 TPBG TJP3

1.08e-0697419026GO:0034330
GeneOntologyCellularComponentglutamatergic synapse

UNC13B VPS18 INPP4A ADGRB2 DOCK10 CRTAC1 ACTN1 ITGA3 PDE10A PIP5K1C DICER1 PTPRT CACNG2 RHOG PTPRD KCND2 PTPRS PAFAH1B1 ELAVL4 NR3C2 RIMS2

1.69e-0581718921GO:0098978
DomainC2

UNC13B INPP4A RASA4 ITSN2 RASA4B PLA2G4F PLCH1 RIMS2 SYT13

8.72e-061371849SM00239
DomainC2

UNC13B INPP4A RASA4 ITSN2 RASA4B PLA2G4F PLCH1 RIMS2 SYT13

1.17e-051421849PS50004
Domain-

UNC13B INPP4A RASA4 ITSN2 RASA4B PLA2G4F PLCH1 RIMS2 SYT13

1.63e-0514818492.60.40.150
DomainRasGAP_dom

GAPVD1 RASA4 RASA4B PLXNB1

2.50e-05181844IPR001936
DomainC2_dom

UNC13B INPP4A RASA4 ITSN2 RASA4B PLA2G4F PLCH1 RIMS2 SYT13

3.67e-051641849IPR000008
DomainC2

UNC13B RASA4 ITSN2 RASA4B PLA2G4F PLCH1 RIMS2 SYT13

4.70e-051311848PF00168
DomainBTK

ITK RASA4 RASA4B

7.56e-0591843SM00107
DomainZnf_Btk_motif

ITK RASA4 RASA4B

7.56e-0591843IPR001562
DomainBTK

ITK RASA4 RASA4B

7.56e-0591843PF00779
DomainZF_BTK

ITK RASA4 RASA4B

7.56e-0591843PS51113
DomainPTPc_motif

DUSP4 PTPN18 PTPRT PTPRD PTPRS

2.86e-04591845SM00404
DomainTyr_Pase_cat

DUSP4 PTPN18 PTPRT PTPRD PTPRS

2.86e-04591845IPR003595
DomainMPI_Phosphatase

CDC25B CDC25C

2.88e-0431842IPR000751
Domain-

RASA4 RASA4B

2.88e-04318424.10.1130.10
DomainM-inducer_phosp

CDC25B CDC25C

2.88e-0431842PF06617
DomainRasGAP

GAPVD1 RASA4 RASA4B

3.92e-04151843PF00616
DomainRAS_GTPASE_ACTIV_1

GAPVD1 RASA4 RASA4B

3.92e-04151843PS00509
DomainRAS_GTPASE_ACTIV_2

GAPVD1 RASA4 RASA4B

3.92e-04151843PS50018
DomainPTPc

PTPN18 PTPRT PTPRD PTPRS

4.20e-04361844SM00194
Domain-

GAPVD1 RASA4 RASA4B

4.79e-041618431.10.506.10
DomainAAA

MCM8 DNAH10 ABCC11 MCM7 HELZ2 ABCD4 TAP1

5.68e-041441847SM00382
DomainAAA+_ATPase

MCM8 DNAH10 ABCC11 MCM7 HELZ2 ABCD4 TAP1

5.68e-041441847IPR003593
DomainPhosphogly_mut1

PGAM1 PGAM4

5.72e-0441842IPR005952
DomainTYR_PHOSPHATASE_PTP

PTPN18 PTPRT PTPRD PTPRS

5.73e-04391844PS50055
DomainPTPase_domain

PTPN18 PTPRT PTPRD PTPRS

6.94e-04411844IPR000242
DomainY_phosphatase

PTPN18 PTPRT PTPRD PTPRS

6.94e-04411844PF00102
DomainTyr_Pase_AS

DUSP4 PTPN18 PTPRT PTPRD PTPRS

7.68e-04731845IPR016130
DomainNIDO_dom

TECTA NID1

9.47e-0451842IPR003886
DomainNIDO

TECTA NID1

9.47e-0451842SM00539
DomainNIDO

TECTA NID1

9.47e-0451842PF06119
DomainNIDO

TECTA NID1

9.47e-0451842PS51220
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

GAPVD1 PDGFRA PPP1R3E PAK5 TRIM68 LBR CARD8 ITK MADD POLR1F DCP1B RBM14 AKAP11 NR3C2 PLEC PLCH1 CDC25B CDC25C KIF13A PHLDB2 DYRK2

1.52e-088611922136931259
Pubmed

Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.

DNAH10 CDK12 DUSP4 POLR2B PIP5K1C PGAM1 SEMA4G ITK KCNH3 RHOG PAFAH1B1 DNAH17 PGAM4 UBA6 PLA2G4F CDC25B ATP4A

7.27e-077301921734857952
Pubmed

Large-scale mapping of human protein-protein interactions by mass spectrometry.

VPS18 GAPVD1 ERP44 FNTA POLR2B PAK5 UBR4 NIPSNAP2 MCM7 LBR TRRAP CCNH CACTIN DFFB FAF2 PTPRS CFAP20 SUN2 MTR FIBP MRPS34 AKAP11 CDC25B

7.66e-0712841922317353931
Pubmed

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.

USP34 VPS18 GAPVD1 ERP44 CDK12 PAK5 TTC14 FASTKD5 ACAD10 TRRAP DICER1 ITK CCNH DFFB CFAP20 FIBP AKAP11 PLEC DYRK2

8.12e-079101921936736316
Pubmed

The protein interaction landscape of the human CMGC kinase group.

FNTA PDGFRA CDK12 POLR2B FASTKD5 MCM7 LBR CACNG2 CCNH SETD2 RASA4 RBM14 MTR FIBP AKAP11 DYRK2

1.81e-066951921623602568
Pubmed

The IA-2 interactome.

PTPRT MADD PTPRS

3.27e-066192316273344
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

UNC13B USP34 CDK12 UBR4 ADGRB2 AMBRA1 ITGA3 PIP5K1C TRRAP MADD KCNH3 DHX30 HEG1 SLC12A4 PTPRS HELZ2 PLEC METTL27 IL4R TJP3

3.62e-0611051922035748872
Pubmed

A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.

USP34 GAPVD1 ERP44 FNTA DUSP4 UBR4 CD109 AMBRA1 PTPN18 DICER1 SNW1 PTPRD FAF2 PTPRS CIBAR1 NID1 CDC25B CDC25C

8.61e-069741921828675297
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

ENTPD7 USP34 ERP44 CD109 DNAJC18 MANEA PGAP4 LBR ITGA3 ATP9A MADD HEG1 PTPRS SUN2 FBXO28 LRRC8A NID1 TAP1 PLXNB1 ADGRA3

1.23e-0512011922035696571
Pubmed

Defining the human deubiquitinating enzyme interaction landscape.

UNC13B ERP44 NIPSNAP2 AMBRA1 SPATA2 TRRAP DICER1 FEM1B POLR1F ERCC8 FAF2 DCP1B SUN2 PKP1 MRPS34 DLST PLEC CDC25B

1.31e-0510051921819615732
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

GAPVD1 ERP44 DNAH10 POLR2B UBR4 POR FASTKD5 MCM7 LBR PGAM1 DICER1 DHX30 RIOX2 SNW1 FAF2 RBM14 UBA6 MTR PKP1 MRPS34 DLST ADGRA3

1.43e-0514251922230948266
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

USP34 MCM8 FAT3 POLR2B AMBRA1 FASTKD5 LBR ITGA3 TRIM27 TRRAP DICER1 SLC4A1 CACTIN SETD2 SUN2 CIBAR1 MTR FIBP PHLDB2

1.51e-0511161921931753913
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

MCM8 CDK12 DOCK10 AMBRA1 DICER1 MADD FREM2 RBM14 MTR PLCH1 CDC25B ZBTB11 PCDHGC3 PLXNB1

1.71e-056501921438777146
Pubmed

Identification of new ciliary signaling pathways in the brain and insights into neurological disorders.

DPP6 ADGRB2 DCC PDE10A ATP9A PIP5K1C SLC4A1 CACNG2 SLC9A1 KCND2 ASTN2

1.74e-054051921138187761
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

UNC13B DOCK10 ATP9A SPATA2 PIP5K1C MADD DHX30 FEM1B FAF2 FBXO28 ITSN2

1.82e-054071921112693553
Pubmed

Disorders of Intracellular Cobalamin Metabolism

MMADHC ABCD4 MTR

1.93e-0510192320301503
Pubmed

Congenic mapping of the diabetogenic locus Idd4 to a 5.2-cM region of chromosome 11 in NOD mice: identification of two potential candidate subloci.

CCL4L1 PAFAH1B1 CCL4

1.93e-0510192311756344
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

POLR2B UBR4 DOCK10 AMBRA1 MCM7 ACTN1 OCRL LBR TRRAP DHX30 RLF POLR1F RHOG SNW1 FAF2 PAFAH1B1 RBM14 PKP1 DLST PLEC PHLDB2

2.10e-0513531922129467282
Pubmed

Molecular genetics of successful smoking cessation: convergent genome-wide association study results.

DPP6 CD109 ATP9A PTPRT PTPRD PKP1

2.15e-05101192618519826
Pubmed

Targeting the p300/NONO axis sensitizes melanoma cells to BRAF inhibitors.

AMBRA1 MCM7 DICER1 RBM14

2.20e-0530192434017080
Pubmed

A transcript finishing initiative for closing gaps in the human transcriptome.

RIPOR3 ACAD10 CACTIN

2.65e-0511192315197164
Pubmed

Functional proteomics mapping of a human signaling pathway.

CDK12 INPP4A UBR4 SVEP1 DHX30 RLF SLC12A4 DCP1B UBA6 NID1 PLEC ZBTB11 KIF13A

2.77e-055911921315231748
Pubmed

The Biology of Cell-free DNA Fragmentation and the Roles of DNASE1, DNASE1L3, and DFFB.

DFFB DNASE1

3.03e-052192232004449
Pubmed

Blood group AB and factor V Leiden as risk factors for pre-eclampsia: a population-based nested case-control study.

ABO F5

3.03e-052192219110300
Pubmed

CDC25B and CDC25C overexpression in nonmelanoma skin cancer suppresses cell death.

CDC25B CDC25C

3.03e-052192231237025
Pubmed

Phospho-Cdc25 correlates with activating G2/M checkpoint in mouse zygotes fertilized with hydrogen peroxide-treated mouse sperm.

CDC25B CDC25C

3.03e-052192225012723
Pubmed

CAPRI regulates Ca(2+)-dependent inactivation of the Ras-MAPK pathway.

RASA4 RASA4B

3.03e-052192211448776
Pubmed

Differing impact of phosphoglycerate mutase 1-deficiency on brown and white adipose tissue.

PGAM1 PGAM4

3.03e-052192235521515
Pubmed

Platelet-activating factor acetylhydrolase gene polymorphism and its activity in Japanese patients with multiple sclerosis.

PLA2G7 PAFAH1B1

3.03e-052192215081260
Pubmed

Ca2+ promotes erythrocyte band 3 tyrosine phosphorylation via dissociation of phosphotyrosine phosphatase from band 3.

SLC4A1 CDC25C

3.03e-052192212175337
Pubmed

PGAM1 is Involved in Spermatogenic Dysfunction and Affects Cell Proliferation, Apoptosis, and Migration.

PGAM1 PGAM4

3.03e-052192225701843
Pubmed

The dual specificity phosphatase Cdc25B, but not the closely related Cdc25C, is capable of inhibiting cellular proliferation in a manner dependent upon its catalytic activity.

CDC25B CDC25C

3.03e-052192217591782
Pubmed

Normal cell cycle and checkpoint responses in mice and cells lacking Cdc25B and Cdc25C protein phosphatases.

CDC25B CDC25C

3.03e-052192215767688
Pubmed

Platelet activating factor-acetylhydrolase (PAF-AH) activity and HDL levels, but not PAF-AH gene polymorphisms, are associated with successful aging in Sicilian octogenarians.

PLA2G7 PAFAH1B1

3.03e-052192218431085
Pubmed

Adventitious arsenate reductase activity of the catalytic domain of the human Cdc25B and Cdc25C phosphatases.

CDC25B CDC25C

3.03e-052192220025242
Pubmed

PDGFRα signaling in the primary cilium regulates NHE1-dependent fibroblast migration via coordinated differential activity of MEK1/2-ERK1/2-p90RSK and AKT signaling pathways.

PDGFRA SLC9A1

3.03e-052192223264740
Pubmed

Colocalization of MCM8 and MCM7 with proteins involved in distinct aspects of DNA replication.

MCM8 MCM7

3.03e-052192218072282
Pubmed

Dual roles of endogenous platelet-activating factor acetylhydrolase in a murine model of necrotizing enterocolitis.

PLA2G7 PAFAH1B1

3.03e-052192220531249
Pubmed

Sequence and expression pattern of an evolutionarily conserved transcript identified by gene trapping.

CFAP20 PAX3

3.03e-05219228688464
Pubmed

[Analysis of 994(G--> T) mutation in the plasma platelet-activating factor acetylhydrolase gene in the patients with cerebral infarction].

PLA2G7 PAFAH1B1

3.03e-052192216086290
Pubmed

A single nucleotide polymorphism within the novel sex-linked testis-specific retrotransposed PGAM4 gene influences human male fertility.

PGAM1 PGAM4

3.03e-052192222590500
Pubmed

Cloning and expression of a lymphocyte activation gene (LAG-1).

CCL4L1 CCL4

3.03e-05219222247088
Pubmed

Encephalitis and antibodies to dipeptidyl-peptidase-like protein-6, a subunit of Kv4.2 potassium channels.

DPP6 KCND2

3.03e-052192223225603
Pubmed

The GOAL study: a prospective examination of the impact of factor V Leiden and ABO(H) blood groups on haemorrhagic and thrombotic pregnancy outcomes.

ABO F5

3.03e-052192218028481
Pubmed

Gene network of a phosphoglycerate mutase in muscle wasting in mice.

PGAM1 PGAM4

3.03e-052192225644094
Pubmed

Dipeptidyl peptidase-like protein 6 is required for normal electrophysiological properties of cerebellar granule cells.

DPP6 KCND2

3.03e-052192220573902
Pubmed

PGAM1 knockdown is associated with busulfan‑induced hypospermatogenesis and spermatogenic cell apoptosis.

PGAM1 PGAM4

3.03e-052192230720109
Pubmed

The second catalytic domain of protein tyrosine phosphatase delta (PTP delta) binds to and inhibits the first catalytic domain of PTP sigma.

PTPRD PTPRS

3.03e-05219229566880
Pubmed

Type I platelet-activating factor acetylhydrolase catalytic subunits over-expression induces pleiomorphic nuclei and centrosome amplification.

PLA2G7 PAFAH1B1

3.03e-052192217903175
Pubmed

The distinct and developmentally regulated patterns of expression of members of the mouse Cdc25 gene family suggest differential functions during gametogenesis.

CDC25B CDC25C

3.03e-05219227601309
Pubmed

Phosphoglycerate Mutase 1 Promotes Cell Proliferation and Neuroblast Differentiation in the Dentate Gyrus by Facilitating the Phosphorylation of cAMP Response Element-Binding Protein.

PGAM1 PGAM4

3.03e-052192230460638
Pubmed

I SA channel complexes include four subunits each of DPP6 and Kv4.2.

DPP6 KCND2

3.03e-052192218364354
Pubmed

T cell-specific deletion of Pgam1 reveals a critical role for glycolysis in T cell responses.

PGAM1 PGAM4

3.03e-052192232709928
Pubmed

An essential function for the calcium-promoted Ras inactivator in Fcgamma receptor-mediated phagocytosis.

RASA4 RASA4B

3.03e-052192216041389
Pubmed

Overexpression of CDC25B, CDC25C and phospho-CDC25C (Ser216) in vulvar squamous cell carcinomas are associated with malignant features and aggressive cancer phenotypes.

CDC25B CDC25C

3.03e-052192220500813
Pubmed

A precise localization of a mouse gene encoding increased phosphoglycerate mutase activity (Pgam1e1) on chromosome 19.

PGAM1 PGAM4

3.03e-05219228829551
Pubmed

DPP6 establishes the A-type K(+) current gradient critical for the regulation of dendritic excitability in CA1 hippocampal neurons.

DPP6 KCND2

3.03e-052192221943606
Pubmed

Patients with cobalamin G or J defect missed by the current newborn screening program: diagnosis and novel mutations.

ABCD4 MTR

3.03e-052192230651581
Pubmed

MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.

ERP44 CDK12 POLR2B UPF3A LBR TRRAP DHX30 SETD2 SNW1 CATSPER2 CFAP20 SUN2 HELZ2 RBM14 MRPS34 DLST PLEC PLXNB1

3.46e-0510821921838697112
Pubmed

Mindbomb 1, an E3 ubiquitin ligase, forms a complex with RYK to activate Wnt/β-catenin signaling.

FAT3 FREM2 PTPRS PCDH9 ADGRA3

3.56e-0567192521875946
Pubmed

Identification of transcripts with enriched expression in the developing and adult pancreas.

VIP EMILIN2 CPZ ITGA3 DCC DICER1 OLFML3 SLC4A1 ADAMTS16 NID1 PAX3 SYT13 TJP3

4.83e-056241921318554416
Pubmed

A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins.

PGAP4 OCRL TRIM27 TRRAP MADD FEM1B SLC9A1 SLC12A4 CFAP20 CIBAR1 ITSN2 ABCD4 KIF13A SYT13

5.12e-057191921435337019
Pubmed

Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.

USP34 ERP44 PDGFRA CD109 POR FASTKD5 MCM7 ACAD10 LBR OLFML3 RHOG HEG1 FAF2 CIBAR1 PKP1 MRPS34 NID1 DLST PLEC TAP1 TPBG

5.75e-0514511922130550785
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

GAPVD1 ERP44 POLR2B MCM7 ACTN1 LBR TRRAP F5 DICER1 DHX30 SNW1 RBM14 UBA6 PKP1 PLEC TAP1 PHLDB2

5.90e-0510241921724711643
Pubmed

Defining the Protein-Protein Interaction Network of the Human Protein Tyrosine Phosphatase Family.

UNC13B GAPVD1 ERP44 DUSP4 POLR2B AMBRA1 PGAP4 PTPN18 PGAM1 GTF2B TRIM11 FAF2 MRPS34 DLST CDC25B CDC25C

6.55e-059311921627432908
Pubmed

Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.

INPP4A UBR4 ACAD10 PIP5K1C F5 MADD DHX30 PKP1 LRRC8A NID1 ELAVL4

7.35e-054751921131040226
Pubmed

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.

POLR2B CD109 MCM7 ACTN1 TRIM27 F5 TASOR2 DHX30 SNW1 SUN2 HELZ2 RBM14 PKP1 LRRC8A MRPS34 DLST PLEC ATP4A PHLDB2

7.49e-0512571921936526897
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

USP34 GAPVD1 UBR4 ACTN1 PGAM1 TRRAP DICER1 TASOR2 DHX30 SNW1 HELZ2 PLEC ZBTB11

7.63e-056531921322586326
Pubmed

The variant Polycomb Repressor Complex 1 component PCGF1 interacts with a pluripotency sub-network that includes DPPA4, a regulator of embryogenesis.

USP34 CDK12 UBR4 MUC16 FASTKD5 PGAM1 ERCC8 TMTC1 CFAP20 MRPS34

7.72e-053961921026687479
Pubmed

Nuclear localization of cyclin B1 controls mitotic entry after DNA damage.

CDC25B CDC25C

9.06e-05319229585407
Pubmed

Cdc25A Is a Critical Mediator of Ischemic Neuronal Death In Vitro and In Vivo.

CDC25B CDC25C

9.06e-053192228607169
Pubmed

Molecular cloning and nucleotide sequence of murine 2,3-bisphosphoglycerate mutase cDNA.

PGAM1 PGAM4

9.06e-05319222847721
Pubmed

A Novel Resolution of Diabetes: C-C Chemokine Motif Ligand 4 Is a Common Target in Different Types of Diabetes by Protecting Pancreatic Islet Cell and Modulating Inflammation.

CCL4L1 CCL4

9.06e-053192233968046
Pubmed

Phosphoglycerate Mutase Cooperates with Chk1 Kinase to Regulate Glycolysis.

PGAM1 PGAM4

9.06e-053192232634742
Pubmed

LAR receptor phospho-tyrosine phosphatases regulate NMDA-receptor responses.

PTPRD PTPRS

9.06e-053192231985401
Pubmed

CD28 inhibits T cell adhesion by recruiting CAPRI to the plasma membrane.

RASA4 RASA4B

9.06e-053192225637021
Pubmed

A gene triplet in the mouse.

DPP6 PDGFRA

9.06e-05319225529676
Pubmed

Trans-synaptic adhesions between netrin-G ligand-3 (NGL-3) and receptor tyrosine phosphatases LAR, protein-tyrosine phosphatase delta (PTPdelta), and PTPsigma via specific domains regulate excitatory synapse formation.

PTPRD PTPRS

9.06e-053192220139422
Pubmed

Critical role of CCL4 in eosinophil recruitment into the airway.

CCL4L1 CCL4

9.06e-053192230854716
Pubmed

Dephosphorylation of human p34cdc2 kinase on both Thr-14 and Tyr-15 by human cdc25B phosphatase.

CDC25B CDC25C

9.06e-05319228440392
Pubmed

Multiple products derived from two CCL4 loci: high incidence of a new polymorphism in HIV+ patients.

CCL4L1 CCL4

9.06e-053192215843566
Pubmed

Intact synapse structure and function after combined knockout of PTPδ, PTPσ, and LAR.

PTPRD PTPRS

9.06e-053192233656439
Pubmed

Platelet-activating factor acetylhydrolases: broad substrate specificity and lipoprotein binding does not modulate the catalytic properties of the plasma enzyme.

PLA2G7 PAFAH1B1

9.06e-053192211294621
Pubmed

Identification, cloning, and characterization of an immune activation gene.

CCL4L1 CCL4

9.06e-05319222462251
Pubmed

HIV-1 Tat interacts with LIS1 protein.

CCNH PAFAH1B1

9.06e-053192215698475
Pubmed

An ATF/CREB-binding site is essential for cell-specific and inducible transcription of the murine MIP-1 beta cytokine gene.

CCL4L1 CCL4

9.06e-05319227835696
Pubmed

Isolation and characterization of a cDNA encoding a putative cytokine which is induced by stimulation via the CD2 structure on human T lymphocytes.

CCL4L1 CCL4

9.06e-05319222568930
Pubmed

Cell cycle regulation by the Cdc25 phosphatase family.

CDC25B CDC25C

9.06e-053192210740819
Pubmed

Dual phosphorylation controls Cdc25 phosphatases and mitotic entry.

CDC25B CDC25C

9.06e-053192212766774
Pubmed

Enhanced Reactive Oxygen Species Production, Acidic Cytosolic pH and Upregulated Na+/H+ Exchanger (NHE) in Dicer Deficient CD4+ T Cells.

DICER1 SLC9A1

9.06e-053192228704808
Pubmed

Bone marrow-derived monocyte lineage cells recruited by MIP-1β promote physiological revascularization in mouse model of oxygen-induced retinopathy.

CCL4L1 CCL4

9.06e-053192221912378
Pubmed

The Nexus of cfDNA and Nuclease Biology.

DFFB DNASE1

9.06e-053192234006390
Pubmed

DPP6 regulation of dendritic morphogenesis impacts hippocampal synaptic development.

DPP6 KCND2

9.06e-053192223912628
Pubmed

Characterization of genetically modified mice for phosphoglycerate mutase, a vitally-essential enzyme in glycolysis.

PGAM1 PGAM4

9.06e-053192233914812
Pubmed

Inhibition of macrophage inflammatory protein-1β improves endothelial progenitor cell function and ischemia-induced angiogenesis in diabetes.

CCL4L1 CCL4

9.06e-053192229987448
Pubmed

The gene encoding the Act-2 cytokine. Genomic structure, HTLV-I/Tax responsiveness of 5' upstream sequences, and chromosomal localization.

CCL4L1 CCL4

9.06e-05319221894635
Pubmed

A genome-wide association study of venous thromboembolism identifies risk variants in chromosomes 1q24.2 and 9q.

ABO F5

9.06e-053192222672568
Pubmed

Cdc25 protein phosphatases in cell proliferation.

CDC25B CDC25C

9.06e-05319229141461
Pubmed

High-resolution solution structure of the beta chemokine hMIP-1 beta by multidimensional NMR.

CCL4L1 CCL4

9.06e-05319228134838
Pubmed

Mouse phosphoglycerate mutase M and B isozymes: cDNA cloning, enzyme activity assay and mapping.

PGAM1 PGAM4

9.06e-053192211250083
GeneFamilyClass III Cys-based CDC25 phosphatases

CDC25B CDC25C

1.83e-0431422713
GeneFamilyBisphosphoglycerate phosphatases

PGAM1 PGAM4

3.64e-04414221082
GeneFamilyProtein tyrosine phosphatases, receptor type

PTPRT PTPRD PTPRS

5.69e-04211423813
CoexpressionMILI_PSEUDOPODIA_HAPTOTAXIS_DN

CD109 POR ITGA3 SPATA2 SLC9A1 HEG1 TRIM11 FAF2 SLC12A4 PTPRS HELZ2 NID1 PLEC PCDHGC3 IL4R ADGRA3 TPBG

1.05e-0568119017M5314
CoexpressionBENPORATH_PRC2_TARGETS

ILDR2 PDGFRA DUSP4 CYP24A1 CRTAC1 DCC GALR2 ALX4 PTPRT PGM5 KCNH3 ADRB3 PKP1 ASTN2 PAX3 PLEC

2.28e-0565019016M8448
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HDA2

DPP6 DUSP4 PAK5 PGAP4 DCC ATP9A ALX4 CACNG2 RASA4 ELAVL4 FRMPD3 RIMS2 SYT13 TPBG

2.46e-0551319014M39069
CoexpressionBENPORATH_EED_TARGETS

PLA2G7 ILDR2 PDGFRA INPP4A DUSP4 CYP24A1 CRTAC1 UPF3A DCC PDE10A GALR2 ALX4 PTPRT PGM5 KCNH3 ADRB3 PKP1 ASTN2 PAX3 PLEC TAP1

3.04e-05105919021M7617
CoexpressionKIM_WT1_TARGETS_8HR_UP

ACTN1 PDE10A ATP9A DICER1 RLF PLEC IL4R TPBG

3.12e-051671908M8857
CoexpressionMEISSNER_BRAIN_HCP_WITH_H3K4ME3_AND_H3K27ME3

UNC13B DPP6 TICRR PDGFRA DUSP4 ADGRB2 EMILIN2 CRTAC1 PDE10A PTPN18 SVEP1 PGM5 KCNH3 FREM2 SLC12A4 PAX3 TAP1 IL4R SYT13 PHLDB2 TPBG

3.73e-05107419021M1941
CoexpressionAtlasDevelopingGonad_e16.5_epididymis_emap-29702_k-means-cluster#4_top-relative-expression-ranked_1000

ILDR2 CDK12 PDE10A RLF HEG1 KCND2 CIBAR1 ADAMTS16 PLEC

1.59e-061271839gudmap_developingGonad_e16.5_epididymis_1000_k4
CoexpressionAtlasDevelopingGonad_e16.5_epididymis_emap-29702_top-relative-expression-ranked_1000

ILDR2 GAPVD1 PDGFRA CDK12 FAT3 TTC14 OCRL PDE10A OLFML3 SVEP1 PGM5 KCNH3 RLF HEG1 KCND2 CIBAR1 PAFAH1B1 ADAMTS16 NID1 PLEC PCDH9

4.86e-0679018321gudmap_developingGonad_e16.5_epididymis_1000
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ILDR2 DNAH10 FAT3 PAK5 DCC TECTA ALX4 PTPRT SVEP1

3.36e-081601929c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ILDR2 DNAH10 FAT3 PAK5 DCC TECTA ALX4 PTPRT SVEP1

3.36e-08160192925c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell(2)_Fibroblasts-(22)_Fibro-3|(2)_Fibroblasts / Cell class and subclass of bone marrow stroma cells in homeostatis

PLA2G7 FAT3 ACTN1 OLFML3 PTPRT CLEC11A NID1 TMEM200C TPBG

2.00e-071971929d9021bab82403e566ec10f78acb227c0f80b88fe
ToppCellLPS_anti-TNF-Endothelial-Endothelial-Vein|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

CRTAC1 ACTN1 F5 PGM5 TMTC1 HEG1 RASA4 LRATD2 PLEC

2.17e-071991929cfb624c7728046fc7f3ef071f57e4d7b013f3fef
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ADGRB2 MUC16 CPZ KCNH3 FREM2 CLEC11A ELAVL4 SYT13

9.19e-0717419284da79da7a09ee1e345102c5331675ebcdbe56171
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAH10 FAT3 DCC FREM2 PTPRD ADAMTS16 ELAVL4 PLCH1

1.40e-0618419282cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAH10 FAT3 DCC FREM2 PTPRD ADAMTS16 ELAVL4 PLCH1

1.40e-0618419282b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAH10 FAT3 DCC FREM2 PTPRD ADAMTS16 ELAVL4 PLCH1

1.40e-061841928ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD8_c01-LEF1|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

INPP4A TTC14 DOCK10 ACTN1 ITK SUN2 ERCC6L2 DYRK2

1.71e-061891928e9df7ecd36bee1fedce23bb188c68a94fa60462c
ToppCellASK428-Epithelial-Transformed_epithelium|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq

ILDR2 PDGFRA RIPOR3 PDE10A F5 HEG1 PHLDB2 TPBG

1.71e-06189192887189275234b5d59484c58acbb14a09903f2b578
ToppCellAdult-Mesenchymal-matrix_fibroblast_2_cell-D175|Adult / Lineage, Cell type, age group and donor

RIPOR3 SVEP1 TMTC1 KCND2 PTPRS ADAMTS16 FRMPD3 PHLDB2

1.78e-0619019287dcca3469f3a3b70db0420cb94f7765f39492f06
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2|Children_(3_yrs) / Lineage, Cell type, age group and donor

UNC13B DPP6 CRTAC1 FREM2 PTPRD NR3C2 PLA2G4F PLCH1

1.85e-061911928a0332a4ef629510fb313ec119195c44a3f704a80
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

UNC13B CRTAC1 FREM2 PTPRD NR3C2 PLA2G4F PLCH1 PCDH9

2.00e-061931928f3cc7cfdbc164a4ed42f87647111522b7d393bcb
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT2-AT2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

UNC13B CRTAC1 FREM2 PTPRD NR3C2 PLA2G4F PLCH1 PCDH9

2.00e-061931928fd4d3c0d7caf8a2fff5b3d901fc28d19a8163cdf
ToppCelldroplet-Pancreas-Endocrine-18m-Epithelial-pancreatic_D_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DPP6 PAK5 OCRL F5 OLFML3 CACNG2 KCND2 PCDH9

2.00e-0619319286995ee29bf403a71247de92a37dfd851be5acf2e
ToppCelldroplet-Pancreas-Endocrine-18m-Epithelial-pancreatic_D_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DPP6 PAK5 OCRL F5 OLFML3 CACNG2 KCND2 PCDH9

2.00e-0619319287fcfb0f76789fa8d8caa18304cb43c8fd899a81b
ToppCell(1)_T_cells-(1)_T_CD4_naive|(1)_T_cells / Spleen cell shreds - cell class (v1) and cell subclass (v1)

PPP1R3E TTC14 ACTN1 PTPN18 ITK SETD2 CLEC11A ERCC6L2

2.16e-061951928d3fa551bc6f5ee5890af1040415e61ecd5d46201
ToppCellParenchymal-NucSeq-Epithelial-Epi_alveolar-AT2|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

UNC13B DPP6 CRTAC1 FREM2 PTPRD NR3C2 PLA2G4F PLCH1

2.42e-0619819282e2a4e1756bba6f4fbe529559a97d2993c890b4b
ToppCellCOVID-19-kidney-Technical/muscle_(PCT)|COVID-19 / Disease (COVID-19 only), tissue and cell type

DPP6 DCC PTPRT PTPRD ELAVL4 RIMS2 PIWIL3

2.45e-061391927a1945b07f177cde40e7eea03a19236ce76165857
ToppCellParenchyma_Control_(B.)-Stromal-TX-Fibroblasts-1|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

PDGFRA FAT3 OLFML3 SVEP1 PTPRD PTPRS NID1 PCDHGC3

2.60e-062001928aa1a35dcca3b799241eef4237f6eb94660e019f0
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-1|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

PDGFRA FAT3 OLFML3 SVEP1 PTPRD PTPRS NID1 PCDHGC3

2.60e-062001928a510deaada669e690329183e18df02870bd204b3
ToppCellLPS_IL1RA_TNF-Endothelial-Endothelial-Vein|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

CRTAC1 ACTN1 PGM5 TMTC1 HEG1 RASA4 LRATD2 PLEC

2.60e-0620019287eb366b2c5394af7c77650bde6261e7dac67154e
ToppCelldistal-mesenchymal-Adventitial_Fibroblast-1|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PDGFRA CPZ OLFML3 SVEP1 PTPRS CLEC11A ADAMTS16 TPBG

2.60e-06200192856e838787385dd282caadeac24fbb0a706bf7f2b
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-1-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PDGFRA FAT3 OLFML3 SVEP1 PTPRD PTPRS NID1 PCDHGC3

2.60e-062001928dd4228cbed8a4395166a6332e08d44d88bebe3b9
ToppCell368C-Fibroblasts-Fibroblast-E|368C / Donor, Lineage, Cell class and subclass (all cells)

TICRR PDGFRA OLFML3 SVEP1 PTPRS CLEC11A PLCH1

6.74e-061621927e17632778a57c71d6005d3abca3a0443a92040e7
ToppCell368C-Fibroblasts-Fibroblast-E-|368C / Donor, Lineage, Cell class and subclass (all cells)

TICRR PDGFRA OLFML3 SVEP1 PTPRS CLEC11A PLCH1

6.74e-061621927ac4a80fd72c9311ea2b3e574c6284bbce4f2756c
ToppCellE17.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

TMC3 OLFML3 SVEP1 PGM5 ADRB3 PTPRD ASTN2

9.23e-0617019277fa022471e14ac8a3bc147c793368a4d56a8e591
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FAT3 DCC PTPRT PTPRD ADAMTS16 PLCH1 PHLDB2

1.25e-0517819270e1bedf991189d0ef9b40dac9281bdf4739333a1
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FAT3 DCC PTPRT PTPRD ADAMTS16 PLCH1 PHLDB2

1.29e-0517919278766a5a066091879f521acfc612abf563ff78808
ToppCell3'-GW_trimst-2-LargeIntestine-Epithelial-epithelial_progenitor_cell-TA|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RNF183 LBR DFFB FRMPD3 PLCH1 CDC25C PLXNB1

1.34e-051801927271ee52ed8f21f78ddf68e52fc88fe582701675e
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

UNC13B ABO CRTAC1 ITGA3 FREM2 NR3C2 PCDH9

1.65e-0518619272ea5ff14861e5f91d0e6a5767c403a24045d715c
ToppCelldroplet-Lung-LUNG-30m-Mesenchymal-fibroblast_of_lung|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDGFRA FAT3 OLFML3 SVEP1 ADRB3 PTPRD ASTN2

1.65e-0518619271ed71b229f40a680071b14f5a7a19706e0fd14b1
ToppCell5'-Adult-Appendix-Mesenchymal-fibroblastic-mLN_Stroma_(FMO2+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PDGFRA RIPOR3 OLFML3 SVEP1 KCND2 PTPRS NID1

1.65e-0518619277582b5154d8e5a4434817b5ab77a10b789ea2288
ToppCelldroplet-Lung-LUNG-30m-Mesenchymal-Alveolar_Fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDGFRA FAT3 OLFML3 SVEP1 ADRB3 PTPRD ASTN2

1.65e-051861927ca5e9c6531cb5d199e27509bfab1d62e3937177e
ToppCellControl-Fibroblasts-Alveolar_FB|Control / group, cell type (main and fine annotations)

DPP6 PDGFRA FAT3 DCC SVEP1 PTPRS NID1

1.71e-05187192792d468dde81125d51daf7abd4703741abe1ab91c
ToppCellControl-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAT3 CPZ DCC ALX4 SVEP1 ASTN2

1.72e-051251926b162a5bfbb8ac5e65e13578fef9de442a9e4fd8b
ToppCelldroplet-Lung-3m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l1|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ILDR2 OLFML3 PTPRD CLEC11A NID1 ASTN2 GNAT2

1.77e-051881927b382d18fb09fb2869f3c151efa71540a7f5ed229
ToppCellE16.5-samps-Mesenchymal|E16.5-samps / Age Group, Lineage, Cell class and subclass

PDGFRA ACTN1 OLFML3 SVEP1 PTPRD PTPRS NID1

1.77e-0518819273f0f662be684e3a4c6652e636cc135a39a1d2790
ToppCelldroplet-Kidney-nan-3m-Mesenchymal|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDGFRA CPZ OLFML3 SVEP1 CLEC11A NID1 TMEM200C

1.90e-0519019272abeb013bb83c578e67dcb985ba44ca63134950b
ToppCellfacs-Aorta-Heart-3m-Mesenchymal-fibroblast|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ILDR2 ADGRB2 EMILIN2 POR OLFML3 HEG1 PTPRS

1.96e-0519119279214655dca96d766737c9f30b624d7fe7050342e
ToppCellEpithelial-alveolar_epithelial_cell_type_2|World / Lineage, Cell type, age group and donor

UNC13B DPP6 CRTAC1 FREM2 NR3C2 PLA2G4F PLCH1

2.03e-05192192758c3737be7acce39fd2b91d70d6d7b2bbaa4f710
ToppCelldroplet-Lung-30m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l49|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PDGFRA FAT3 OLFML3 SVEP1 ADRB3 PTPRD ASTN2

2.03e-051921927ff4b728a55c2550c806c47e9ae3d057c35df8464
ToppCelldroplet-Lung-30m-Mesenchymal-fibroblast-alveolar_fibroblast|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PDGFRA FAT3 OLFML3 SVEP1 ADRB3 PTPRD ASTN2

2.03e-0519219272d3790bd80a7f214b37094121a2a86ff16362569
ToppCellAdult-Mesenchymal-matrix_fibroblast_2_cell|Adult / Lineage, Cell type, age group and donor

RIPOR3 SVEP1 TMTC1 KCND2 PTPRS NID1 PHLDB2

2.03e-051921927d21f0f577156f17c899b08871046a26b88aea011
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

PDGFRA FAT3 SVEP1 HEG1 PTPRS NID1 PHLDB2

2.10e-051931927b3ad5ff480d99217f36cc7471e5a96a519ddb409
ToppCellLPS-antiTNF-Stromal_mesenchymal|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAT3 DCC SVEP1 PGM5 PTPRD PTPRS NID1

2.17e-0519419276e13549f697f7478b34fe71f7dd9d63c5d3db22e
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

UNC13B DPP6 FREM2 PTPRD NR3C2 PLA2G4F PLCH1

2.17e-05194192797534c8bba895a7913665e03ae4e5c4a6ad71daf
ToppCellSmart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

FAT3 MUC16 ACTN1 PDE10A F5 PTPRT PTPRD

2.24e-05195192719853c654ac64b3ae3bc99841c6cb29c8aaba85c
ToppCellSmart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

FAT3 MUC16 ACTN1 PDE10A F5 PTPRT PTPRD

2.24e-051951927d3755929ebbbf5e3afde44281e9056ddb614a291
ToppCell5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_pulmonary-EC_venous_pulmonary_L.2.2.2.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CD109 ACTN1 PGM5 TMTC1 HEG1 RASA4 RASA4B

2.24e-05195192781a98ebb0d43f416f9a8bba580531dc0cfea8f74
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PDGFRA FAT3 OLFML3 SVEP1 PTPRD PTPRS NID1

2.32e-0519619279737a5f006d37b549f281e1863aca558e1e4dc99
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PDGFRA FAT3 OLFML3 SVEP1 PTPRD PTPRS NID1

2.32e-051961927cecf82cd5e0a3835d655f5e7478578674a63ce25
ToppCellCD8+_Memory_T_cell-CV-3|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster

DUSP4 MCM7 ACTN1 LBR SUN2 PLEC PHLDB2

2.39e-0519719279fe3d53346a95c1bbb0fc6a2f2e974889873424b
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PDGFRA FAT3 OLFML3 SVEP1 PTPRD PTPRS NID1

2.39e-05197192713896ec65ccda0b928c91d41112dc01b480036b7
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PDGFRA OLFML3 SVEP1 PTPRD PTPRS NID1 PCDHGC3

2.39e-05197192794a9603cbd3516fbcce871909693b88f20d41713
ToppCellCV-Moderate-3|CV / Virus stimulation, Condition and Cluster

DUSP4 MCM7 ACTN1 LBR SUN2 PLEC PHLDB2

2.39e-0519719277031286e300eaccf73b927939f8de3a9d2d5fc74
ToppCellBronchial-NucSeq-Epithelial-Epi_alveolar-AT2|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

UNC13B DPP6 CRTAC1 DCC FREM2 PLA2G4F PLCH1

2.47e-051981927f948391296c261c473d339069a6d0f20ccd6f38f
ToppCell10x5'v1-week_12-13-Mesenchymal_osteo|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

PDGFRA FAT3 CHST6 CPZ OLFML3 SVEP1 TPBG

2.55e-051991927bf138cc692df727e087d140c014149ee5da00d9d
ToppCell10x5'v1-week_12-13-Mesenchymal_osteo-stroma|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

PDGFRA FAT3 CHST6 CPZ OLFML3 SVEP1 TPBG

2.55e-051991927d65ee89d5c7e8ed693d58e6a6de09565840e11c5
ToppCell3'-GW_trimst-1-SmallIntestine-Mesenchymal|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PDGFRA ACTN1 OLFML3 SVEP1 CLEC11A NID1 TPBG

2.55e-05199192736c1deac7ef0f9ebde6b2f7a63f7daa03d8c139a
ToppCell5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-immature_mesenchymal_cell|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

OLFML3 SVEP1 HEG1 CLEC11A CIBAR1 NID1 TPBG

2.55e-0519919273cf62666ffd000427fdbb7cf940793f98c3ed29c
ToppCellControl_saline-Endothelial-Endothelial-Vein|Control_saline / Treatment groups by lineage, cell group, cell type

CRTAC1 ACTN1 PGM5 HEG1 RASA4 LRATD2 PLEC

2.64e-052001927e5f876910bc8cb390d9b46a48d9b6d4d57235551
ToppCelldistal-mesenchymal-Adventitial_Fibroblast|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PDGFRA CPZ OLFML3 SVEP1 PTPRS CLEC11A ADAMTS16

2.64e-052001927687cfada2d0977e8985e0a73a5804f84f2ca9c52
ToppCelldistal-1-mesenchymal-Adventitial_Fibroblast|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PDGFRA CPZ OLFML3 SVEP1 PTPRS CLEC11A TPBG

2.64e-052001927738060ed65fa5473fdb39e686f7cdecc059ed92c
ToppCell(01)_IL1RL1+|World / shred by cell type by condition

CD109 ACTN1 ITGA3 PGAM1 PTPRS PGAM4 PLEC

2.64e-052001927501420901bf3ec1b050e0d14596a9f9f3fdfc928
ToppCellprimary_visual_cortex-Non-neuronal-leptomeningeal_cell-VLMC-VLMC_Spp1_Col15a1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PDGFRA RIPOR3 CPZ OLFML3 SVEP1 NID1

3.53e-051421926f4e4cde228149d5a536fbf0517ed71d81e296faf
ToppCellfrontal_cortex-Non-neuronal-leptomeningeal_cell-VLMC-VLMC_Spp1_Col15a1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PDGFRA RIPOR3 CPZ OLFML3 SVEP1 NID1

6.63e-05159192634c90711c5857cf6ada7b3acff99f1d48c7caf29
ToppCellVE-CD8-CD4_Treg|VE / Condition, Cell_class and T cell subcluster

ENTPD7 ATP9A F5 ERCC8 ROPN1L TJP3

7.11e-051611926a114f4f75859d9ef900e5146686438d051241429
ToppCellfacs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DNAH10 FAT3 TECTA F5 FREM2 RIMS2

7.35e-051621926bf886e22ff2a20353499004b53f25fb9e6574896
ToppCellBrain_organoid-organoid_Velasco_nature-3_mon-Neuronal-Cajal-Retzius|3_mon / Sample Type, Dataset, Time_group, and Cell type.

CRTAC1 DCC KLHDC9 SVEP1 CLEC11A TPBG

7.35e-0516219261f589a763f3fd4e1e612809ef3903879d47dc1d8
ToppCellwk_15-18-Mesenchymal-Myofibro_&_SMC-Myofibro_3|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

ENTPD7 TICRR PDGFRA FAT3 ADGRB2 ADGRA3

7.87e-051641926583dda853cee9491dbdcb228c23d8deadc20eb08
ToppCellfacs-Liver-Liver_non-hepato/SCs-18m-Myeloid-neutrophil|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLA2G7 EMILIN2 CRTAC1 ACTN1 TMC3 FRMPD3

8.14e-0516519264fe7c3c9370a556cf4e308a2e723b4b907a6cc25
ToppCellmetastatic_Lymph_Node-Myeloid_cells-CD141+_DCs|metastatic_Lymph_Node / Location, Cell class and cell subclass

ILDR2 DUSP4 ACTN1 ADRB3 APOL3 TAP1

8.41e-0516619269f14e3ef19d5903278c040be1c477501237173fa
ToppCell368C-Myeloid-Monocyte-CD16+_Monocyte|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

INPP4A CRTAC1 ITGA3 SPATA2 KLHDC9 PCDH9

8.70e-051671926dbd2b9f2f4ba7be5fdf8318094e6b078cb1d1c43
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ILDR2 DPP6 ITGA3 F5 PTPRD TMEM200C

8.99e-051681926fc80e4fecfc92458eb627013a983041d8ca025a9
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-5_RORB_CMAHP|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DCC PTPRT ADAMTS16 PKP1 PLCH1 PHLDB2

8.99e-0516819261d58731a481ecac84c15affa84f8041dd67d944c
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ILDR2 DPP6 ITGA3 F5 PTPRD TMEM200C

8.99e-051681926315ca578c945aeeb77acda2727f3e6db8b43f43e
ToppCellChildren_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

ILDR2 DUSP4 RNF183 PDE10A NPC1L1 RIMS2

9.29e-05169192696a2aec9acf8a6f966973c035e5ade456cf47772
ToppCellfacs-Diaphragm-Limb_Muscle-24m|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAH10 FAT3 DCC PTPRT PLCH1 RIMS2

9.29e-05169192612bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCell368C-Myeloid-Monocyte-CD16+_Monocyte|Monocyte / Donor, Lineage, Cell class and subclass (all cells)

INPP4A CRTAC1 ITGA3 SPATA2 KLHDC9 PCDH9

9.59e-0517019264a19c7e3bb0f9c2601a10debe7000066789b4150
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-5_RORB_CMAHP|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DCC PTPRT PTPRD PKP1 PLCH1 PHLDB2

9.59e-05170192649fc45d8a5c3ad89d1649fa46d7a285891379392
ToppCelldroplet-Skin-nan-18m-Epithelial-keratinocyte_stem_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDGFRA F5 GALR2 ALX4 SVEP1 PTPRD

9.59e-05170192610e0912dd0beab5d0bbe2bd49e477b5962687925
ToppCellfrontal_cortex-Non-neuronal-leptomeningeal_cell|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PDGFRA RIPOR3 OLFML3 ALX4 SVEP1 NID1

9.91e-0517119262e43fb129ee9bdc3b31febc43c10f959bf0f4a7d
ToppCellCOVID-19-Heart-T_cell|COVID-19 / Disease (COVID-19 only), tissue and cell type

DCC PTPRT ITK SLC4A1 PAX3 RIMS2

9.91e-051711926b2e753e811a7639956994609f73efcdb62d04f82
ToppCellfrontal_cortex-Non-neuronal-leptomeningeal_cell-VLMC|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PDGFRA RIPOR3 OLFML3 ALX4 SVEP1 NID1

9.91e-051711926e219a1aa59a96e4bc3e2eacf985679174a51de41
ToppCellCOVID-19_Convalescent-cDC|COVID-19_Convalescent / Disease condition and Cell class

ENTPD7 ILDR2 DNAH10 MAGEF1 DLST METTL27

9.91e-0517119269ccaa9f1629818b0f63a5d930ee78c01e04cd98d
ToppCellCOVID-19_Convalescent-cDC-|COVID-19_Convalescent / Disease condition and Cell class

ENTPD7 ILDR2 DNAH10 MAGEF1 DLST METTL27

9.91e-051711926fb5fae8b3adafcbb7c5618d887966b418355ed4d
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-5_RORB_CMAHP|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DCC PTPRT ADAMTS16 PKP1 PLCH1 PHLDB2

9.91e-0517119269d5cabd71a901a00eb16c4d151189296f1b3bf6f
ToppCell3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PDGFRA TECTA OLFML3 SVEP1 NID1 PCDHGC3

1.02e-041721926e37c0b5b547a7345179ab258dd2141fec7064c17
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ILDR2 DPP6 ITGA3 F5 PTPRD TMEM200C

1.02e-0417219266c17a1e586a72d1bd80c20c06370429c61dc9f85
ToppCellMS-CD8-proli_CD4|MS / Condition, Cell_class and T cell subcluster

PPP1R3E TRIM68 SPATA2 TASOR2 ABCD4 DNASE1

1.02e-0417219260b6dd257110b3f17fa71ab18a165b091a9d5ae9a
ToppCellPND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ILDR2 MUC16 CPZ FREM2 PTPRD KCND2

1.09e-041741926a9c6edf5c3fc119c24425f921c5566a8356c30fe
ToppCellprimary_visual_cortex-Non-neuronal-leptomeningeal_cell-VLMC|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PDGFRA RIPOR3 CPZ OLFML3 SVEP1 NID1

1.09e-041741926eade55f86ef1f7a5355ad65cec3aa6bfc5d3c62d
ToppCellPND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TICRR CD109 CPZ KLHDC9 SUN2 CIBAR1

1.09e-0417419261779e67382cb2644534ffb5b9b8f28d32935f4ea
ToppCellprimary_visual_cortex-Non-neuronal-leptomeningeal_cell|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PDGFRA RIPOR3 CPZ OLFML3 SVEP1 NID1

1.09e-0417419262891ab2fd05eb4bbd239d1a2865f21ef7f2df39e
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-5_RORB_CMAHP|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DCC PTPRT ADAMTS16 PKP1 PLCH1 PHLDB2

1.09e-041741926df5664da3b93c233509781429a9c6d7edf1b8944
ToppCellfacs-SCAT-Fat-24m-Lymphocytic-CD8-positive,_alpha-beta_T_cell|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VIP PTPN18 ITK SUN2 PKP1 CCL4

1.09e-04174192687fa5deff5c1aabb342d674f05ad17c4c0e50d01
ToppCellPND03-Epithelial-Epithelial_Airway-Neurosecretory-PNEC-PNEC_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DPP6 PAK5 F5 SLC4A1 ELAVL4 RIMS2

1.12e-0417519268362a46f5804333baa84cd56d450bc147f372a7e
ToppCellAdult-Epithelial-lung_neuroendocrine_cell_(PNEC)-D231|Adult / Lineage, Cell type, age group and donor

RNF183 F5 CACNG2 KCND2 RIMS2 PCDH9

1.12e-0417519268d9f44a2633b71fb4d2b4a7d9530f954e07c4a18
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-5_RORB_CMAHP|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DCC PTPRT ADAMTS16 PKP1 PLCH1 PHLDB2

1.12e-041751926d4827b4dfad07f11cbdd47fbed287af1afb9b1b8
DiseaseDisorders of Intracellular Cobalamin Metabolism

MMADHC ABCD4 MTR

2.68e-05101823cv:CN043592
Diseasehypereosinophilic syndrome (is_implicated_in)

PDGFRA F5

3.78e-0521822DOID:999 (is_implicated_in)
Diseasecolorectal cancer (is_implicated_in)

CYP24A1 DCC DICER1 ALX4 PTPRT SETD2

1.08e-041211826DOID:9256 (is_implicated_in)
Diseasevulva squamous cell carcinoma (is_marker_for)

CDC25B CDC25C

1.13e-0431822DOID:2101 (is_marker_for)
DiseaseCD109 antigen measurement

ABO CD109

1.13e-0431822EFO_0008076
Diseasetotal campesterol measurement

ABO NPC1L1

1.13e-0431822EFO_0020962
Diseaseresponse to anti-tuberculosis drug, drug-induced liver injury

PTPRD ASTN2

1.13e-0431822EFO_0004228, EFO_0007918
DiseaseSushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 measurement

ABO SVEP1

2.25e-0441822EFO_0803113
DiseaseMethylmalonic aciduria and homocystinuria

MMADHC ABCD4

3.74e-0451822cv:CN293516
DiseaseIgE RESPONSIVENESS, ATOPIC

PLA2G7 IL4R

3.74e-0451822C1840253
DiseaseColorectal Carcinoma

UNC13B VPS18 ZNF155 CD109 DCC F5 PTPRT GTF2B PTPRD PTPRS ABCD4 NID1 NR3C2

4.43e-0470218213C0009402
DiseaseProstatic Neoplasms

VIP ABO ERP44 CDK12 DHX30 CCNH SETD2 FAF2 ITSN2 TAP1 TPBG TJP3

4.71e-0461618212C0033578
DiseaseMalignant neoplasm of prostate

VIP ABO ERP44 CDK12 DHX30 CCNH SETD2 FAF2 ITSN2 TAP1 TPBG TJP3

4.71e-0461618212C0376358
Diseasebreast carcinoma (is_marker_for)

PDGFRA CYP24A1 SNW1 CDC25B

7.49e-04661824DOID:3459 (is_marker_for)
Diseaseperipheral vascular disease

ABO F5

7.79e-0471822EFO_0003875
Diseasetoll-like receptor 4:Lymphocyte antigen 96 complex measurement

ABO ASTN2

7.79e-0471822EFO_0008301
DiseaseHematological Disease

SLC4A1 MTR

1.03e-0381822C0018939
Diseasemean arterial pressure

DUSP4 DOCK10 UPF3A PDE10A SVEP1 POLR1F ROPN1L SLC9A1 PTPRD DLST

1.13e-0349918210EFO_0006340
Diseaseanemia (phenotype), response to ribavirin

CYP24A1 DNAH17

1.32e-0391822EFO_0004272, GO_1901559
Diseasepulmonary sarcoidosis (is_implicated_in)

VIP ABO

1.32e-0391822DOID:13406 (is_implicated_in)
Diseaseendometrial hyperplasia (is_marker_for)

CDC25B CDC25C

1.65e-03101822DOID:0080365 (is_marker_for)
Diseasedry eye syndrome (is_marker_for)

MUC16 CCL4

1.65e-03101822DOID:10140 (is_marker_for)
Diseaseneuroimaging measurement, brain volume measurement

USP34 EEF1AKMT4-ECE2 FAT3 DCC ALX4 POLR1F PLEC

2.07e-032861827EFO_0004346, EFO_0006930
Diseaseliver fat measurement

RIOX2 PLEC DNASE1

2.38e-03431823EFO_0010821
DiseaseOligospermia

DICER1 PIWIL3

2.40e-03121822C0028960
DiseaseSpina Bifida

PDGFRA PAX3

2.40e-03121822C0080178
DiseaseStatus Dysraphicus

PDGFRA PAX3

2.40e-03121822C0038219
DiseaseRachischisis

PDGFRA PAX3

2.40e-03121822C0266508
Diseaseeye morphology measurement

ATP9A ALX4 PTPRT CFAP20 ASTN2 NR3C2

2.40e-032181826EFO_0007858
Diseasenasopharyngeal neoplasm

DPP6 CDK12 CRTAC1 MANEA ADGRA3

2.50e-031511825EFO_0004252
Diseasehippocampal volume

DPP6 CRTAC1 MADD PTPRD ASTN2 NR3C2 PLEC

2.55e-032971827EFO_0005035
Diseaseplatelet component distribution width

VPS18 GAPVD1 ABO DOCK10 RIPOR3 CRTAC1 ACTN1 SVEP1 VPS9D1 SETD2 NR3C2 PLEC

2.64e-0375518212EFO_0007984
Diseaseesophagus squamous cell carcinoma (is_implicated_in)

CYP24A1 DCC PTPRT

2.71e-03451823DOID:3748 (is_implicated_in)
Diseaseleukemia (is_implicated_in)

ABO PDGFRA

2.82e-03131822DOID:1240 (is_implicated_in)
Diseasehomocysteine measurement

OLFML3 POLR1F MTR

2.88e-03461823EFO_0004578
DiseaseAdenocarcinoma of large intestine

CDK12 PAK5 DCC TRRAP

2.99e-03961824C1319315
DiseaseGastrointestinal Stromal Sarcoma

PDGFRA ZBTB11 DYRK2

3.07e-03471823C3179349
Diseasebone mineral accretion measurement, response to corticosteroid

DPP6 PTPRT

3.28e-03141822EFO_0007591, GO_0031960
DiseaseSchizophrenia

VIP AMBRA1 FASTKD5 DCC TRRAP DICER1 CACNG2 PAFAH1B1 MTR ASTN2 CDC25C RIMS2 TAP1

3.42e-0388318213C0036341
Diseaselung adenocarcinoma (is_implicated_in)

CYP24A1 ALX4 SETD2

3.45e-03491823DOID:3910 (is_implicated_in)
Diseaseepilepsy (implicated_via_orthology)

UNC13B ITGA3 RHOG SLC12A4 ATP4A

3.48e-031631825DOID:1826 (implicated_via_orthology)
Diseaseplatelet measurement

ABO DOCK10 ACAD10 ACTN1 SVEP1 ERCC8 PLEC

3.53e-033151827EFO_0005036
Diseasegastroesophageal reflux disease

MON1A DCC PTPRT PCDH9

3.59e-031011824EFO_0003948
DiseaseGastrointestinal Stromal Tumors

PDGFRA ZBTB11 DYRK2

3.66e-03501823C0238198
Diseaselysophosphatidylethanolamine 18:0 measurement

TMTC1 ADAMTS16

3.77e-03151822EFO_0010367
Diseasecholesteryl esters:total lipids ratio, high density lipoprotein cholesterol measurement

ABO DNAH10 INHBC CRTAC1 MADD ATP4A

4.09e-032431826EFO_0004612, EFO_0020944
Diseaseinterferon gamma measurement, platelet-derived growth factor BB measurement, interleukin 4 measurement, interleukin 10 measurement, stromal cell-derived factor 1 alpha measurement, interleukin-6 measurement, interleukin 12 measurement, interleukin 17 measurement, vascular endothelial growth factor measurement, fibroblast growth factor basic measurement, granulocyte colony-stimulating factor measurement

ABO F5

4.29e-03161822EFO_0004750, EFO_0004753, EFO_0004762, EFO_0004810, EFO_0008130, EFO_0008142, EFO_0008165, EFO_0008174, EFO_0008184, EFO_0008264, EFO_0008293
Diseasenervousness

MADD DLST

4.29e-03161822NCIT_C74532
Diseaselevel of Sterol ester (27:1/18:0) in blood serum

ABO NPC1L1

4.29e-03161822OBA_2045196
Diseasemean platelet volume

ABO CDK12 CYP24A1 DOCK10 ACTN1 SVEP1 SETD2 FBXO28 PAFAH1B1 LRRC8A NID1 NR3C2 PLEC PCDHGC3

4.48e-03102018214EFO_0004584
DiseaseAcute Cerebrovascular Accidents

PLA2G7 ABO F5

4.54e-03541823C0751956
DiseaseMetastatic melanoma

PDGFRA PAK5 ITK

4.54e-03541823C0278883
DiseaseInborn Errors of Metabolism

PLA2G7 ABCD4

4.84e-03171822C0025521
Disease1-Methylhistidine measurement

CDK12 KCND2

4.84e-03171822EFO_0021543
Diseasesphingomyelin 14:0 measurement

PAK5 NID1

4.84e-03171822EFO_0010390
DiseaseIschemic stroke, venous thromboembolism, stroke, Abnormal thrombosis, deep vein thrombosis, pulmonary embolism

ABO F5

4.84e-03171822EFO_0000712, EFO_0003827, EFO_0003907, EFO_0004286, HP_0001977, HP_0002140
DiseaseFetal Alcohol Syndrome

VIP PDGFRA

4.84e-03171822C0015923
DiseaseCongestive heart failure

PDGFRA SLC9A1 ADRB3 NR3C2

4.86e-031101824C0018802
DiseaseHeart failure

PDGFRA SLC9A1 ADRB3 NR3C2

4.86e-031101824C0018801
DiseaseLeft-Sided Heart Failure

PDGFRA SLC9A1 ADRB3 NR3C2

4.86e-031101824C0023212
DiseaseHeart Failure, Right-Sided

PDGFRA SLC9A1 ADRB3 NR3C2

4.86e-031101824C0235527
DiseaseHeart Decompensation

PDGFRA SLC9A1 ADRB3 NR3C2

4.86e-031101824C1961112
DiseaseMyocardial Failure

PDGFRA SLC9A1 ADRB3 NR3C2

4.86e-031101824C1959583
Diseasepancreatic cancer (is_implicated_in)

ABO PDGFRA SNW1 MTR

5.18e-031121824DOID:1793 (is_implicated_in)
Diseasesmoking behavior

GAPVD1 ADGRB2 DOCK10 ACTN1 DCC ELAVL4 PCDH9

5.42e-033411827EFO_0004318
Diseaseandrostenedione measurement, estrone measurement

OR4D1 PTPRD

5.42e-03181822EFO_0007970, EFO_0007972
DiseaseUterine leiomyoma, estrogen-receptor positive breast cancer

MCM8 ASTN2

5.42e-03181822EFO_1000649, HP_0000131
Diseaseparahippocampal gyrus volume measurement

MAGEF1 FREM2

5.42e-03181822EFO_0010318
Diseaseheel bone mineral density, urate measurement

PDGFRA PDE10A ASTN2 PLCH1 PHLDB2

5.53e-031821825EFO_0004531, EFO_0009270
Diseaseresponse to efavirenz, virologic response measurement

MANEA ALX4 CIBAR1

5.55e-03581823EFO_0006904, EFO_0006906
Diseaseheart failure

ABO DNAJC18 ACAD10 OCRL TMTC1

5.92e-031851825EFO_0003144
Diseasecigarettes per day measurement

FNTA AMBRA1 CRTAC1 DCC VPS9D1 PTPRD ELAVL4 PCDH9

6.03e-034381828EFO_0006525
Diseasebody mass index, high density lipoprotein cholesterol measurement

DNAH10 INHBC

6.04e-03191822EFO_0004340, EFO_0004612
Diseaseinsulin sensitivity measurement, body mass index

ARHGAP40 CYP24A1

6.04e-03191822EFO_0004340, EFO_0004471
Diseasetriglyceride measurement, body mass index

DNAH10 INHBC

6.04e-03191822EFO_0004340, EFO_0004530
DiseasePolydactyly

LBR ALX4 BBS10 FREM2

6.04e-031171824C0152427
Diseasecreatinine measurement, glomerular filtration rate

INHBC CDK12 CYP24A1 ASTN2

6.04e-031171824EFO_0004518, EFO_0005208

Protein segments in the cluster

PeptideGeneStartEntry
RPAAVQTEEQYRFLY

PTPN18

271

Q99952
APEVINYADYSLRST

SYT13

91

Q7L8C5
STAYELPLLTRAENY

ALX4

286

Q9H161
SLQELLARRTYYSGD

ADGRB2

621

O60241
ARLYNSEESRPYTNK

CDK12

881

Q9NYV4
LNELDYYDSPSVNAR

ACTN1

461

P12814
NRIALTDAYLLYTPS

CCNH

196

P51946
REAFTYERRPQSQAY

ABO

241

P16442
YVFSEYTRSPRQDLE

CATSPER2

261

Q96P56
IRRRYPYYLSDITDA

SLC4A1

386

P02730
ASRLTVLREYAYDVP

ADGRA3

1181

Q8IWK6
SNPTYYIRLANRDLV

ACAD10

296

Q6JQN1
ERTLDPYRNEVSQLY

AKAP11

1441

Q9UKA4
YARPSSASIRDANLY

ELAVL4

126

P26378
RDTALLARLLYHTYP

ANKRD61

326

A6NGH8
ESRIRSYLREVSSYP

DFFB

161

O76075
GRAYYTLNVLRDDID

ABCD4

126

O14678
LAVDRYLAVTNPLRY

ADRB3

131

P13945
AYIRLRQRVSYPTAE

AMBRA1

286

Q9C0C7
RFDLPTEYRSYVQSK

DICER1

536

Q9UPY3
SSRENYLEENLLYAP

DHX30

956

Q7L2E3
ATLRNYDYYASRVPE

BPNT1

286

O95861
LSLERNRLTDYYEPL

BBS10

526

Q8TAM1
LRSAYIQSRVETVPY

ASTN2

1281

O75129
FDYRRSYNEPENLIA

ADAMTS16

816

Q8TE57
VRLRDETVLPSSYYQ

RASA4

256

O43374
YERTRLSPPRASYDD

RBM14

576

Q96PK6
RSGPNIYELRSYQLR

NIPSNAP2

181

O75323
VRLRDETVLPSSYYQ

RASA4B

256

C9J798
ASVLVNYRALYPFEA

ITSN2

756

Q9NZM3
LNRAIADYLRSNGYE

PAFAH1B1

11

P43034
LYVVYNTRPASRARI

OLFML3

331

Q9NRN5
APTIATYLSLQYRRD

INPP4A

661

Q96PE3
YIATQYSLRPRREEV

LBR

161

Q14739
LPRLDRYSQYSAVVL

KCNH3

346

Q9ULD8
ELRYFADTQPAYRIL

LRRC8A

6

Q8IWT6
RATLRLYAESYERDP

PGM5

516

Q15124
DYLQASAITRIPSYR

CACNG2

216

Q9Y698
LDDYDRRPKSSYLNQ

PAK5

261

Q9P286
DRYAAIRNPLLYTVA

OR9I1

121

Q8NGQ6
VSKYSDIQRSLYDRP

PDGFRA

751

P16234
PYTNNTLFETDERYR

MMADHC

236

Q9H3L0
ELGPYTLDRDSLYVN

MUC16

13891

Q8WXI7
SPYAETVRVDSKQRY

DCC

766

P43146
LSSRRSDGYPVLEYI

NR3C2

566

P08235
PIRTSEDVSQRVYLY

MADD

1271

Q8WXG6
EDFVQQRYLSYRRVP

MAGEF1

216

Q9HAY2
ELLPRLQARYYSIAS

POR

446

P16435
YVYPRLSTEAARVLQ

MCM8

676

Q9UJA3
DYPNLRTAQLVYDRE

ENTPD7

496

Q9NQZ7
DLARYPSYSQAQALR

JMJD7

246

P0C870
ARRPLSLLYYDRDSN

INHBC

321

P55103
LLDFTRRAYGTNYIE

CFAP20

136

Q9Y6A4
LRYTGPEDADYTNLI

FREM2

2526

Q5SZK8
ASIAEDYRKRAPYIA

GAPVD1

1201

Q14C86
NRSESDIRYLLGYVS

FEM1B

26

Q9UK73
NNGLYSPVYLLDRER

CCNYL2

306

Q5T2Q4
RKLPRNFVVDYYETS

CCL4

41

P13236
RYYADIRQTVPASDQ

PLXNB1

2051

O43157
PNYRRNITLAYTLEA

ITGA3

506

P26006
DRYVAICDPLRYATV

OR51I2

121

Q9H344
DTAGNASYIYDLIRR

PCDH9

776

Q9HC56
AYADPRFNREVDLYT

PDE10A

346

Q9Y233
YADSRPPRSTARELY

PERCC1

116

A0A1W2PR82
YYREDLSPSITQRAA

NID1

121

P14543
RAVYSDRQIYLLDDP

ABCC11

646

Q96J66
DLSVYFLPVARYIRA

DUSP13

111

Q9UII6
TVEYLLRLAAAPSRY

KCND2

241

Q9NZV8
IRERDRAVNDYPSLY

CDC25B

501

P30305
VVNDLYRYKPLSSSA

LRATD2

166

Q96KN1
PFYSNISKDRRYADL

PGAM4

131

Q8N0Y7
PTAADLLQIRSYVYA

ATP9A

211

O75110
YNPSFISDESRRRDY

HEG1

1366

Q9ULI3
APAARRTLTYLSQVY

PGAP4

341

Q9BRR3
KQSRDLYRAPVSSLY

PCDHGC3

721

Q9UN70
TYEPQDFYRLVALSR

PLA2G4F

806

Q68DD2
PRYDYILATASADSR

ERCC8

196

Q13216
YSKERATYALDRQLP

MANEA

446

Q5SRI9
LSYIDRLAPRSQYTT

MCM7

391

P33993
LREEDRSLNQYPALY

CDC25C

391

P30307
LRLYYPSQDNDRLDT

PLA2G7

81

Q13093
ETLHYFRDLYLPASR

RDH8

211

Q9NYR8
APDYDQDVATLLYRA

METTL27

36

Q8N6F8
YSSPANLYVRELREV

PTPRS

226

Q13332
FRSLYYNISRLDPQT

PTPRT

1156

O14522
THYPDIYTREELAQR

PAX3

241

P23760
REEEYQSRYRSDPNL

RIMS2

356

Q9UQ26
QSRYRSDPNLARYPV

RIMS2

361

Q9UQ26
ILTAPNRSSYRYDSL

NPC1L1

411

Q9UHC9
YRDYIDISVAVATPR

DLST

311

P36957
LALREALRTPYYSVA

MON1A

521

Q86VX9
QDPFLLYRNARLSIY

DCP1B

96

Q8IZD4
LAAVSLDRYLAIRYP

GALR2

116

O43603
LPSRDYYLNRTANEK

EEF1AKMT4-ECE2

376

P0DPD8
DASVSIVDYYEPRRQ

CD109

1376

Q6YHK3
LRPEYRVHSYNASET

FASTKD5

121

Q7L8L6
DFRIYNVTYLEPSLR

IL4R

171

P24394
NEALYPQRRSYTSED

GRHL1

16

Q9NZI5
RKLPRNFVVDYYETS

CCL4L1

41

Q8NHW4
LNRNFPDLTSEYYRL

CPZ

321

Q66K79
YSLANSYASTPELRR

DOCK10

1686

Q96BY6
FRNSLYAPDYSSRLD

CIBAR1

221

A1XBS5
YAPDYSSRLDIVRAN

CIBAR1

226

A1XBS5
EALYRTESAYPQRLE

CYP24A1

116

Q07973
YRPAAERASLLYFIL

DNAH17

3651

Q9UFH2
RYLFVYRPDQVSAVD

DNASE1

101

P24855
RDPAAFEYLYIQSRN

FRMPD3

276

Q5JV73
EIYRVLRYVNSTRAP

FBXO28

176

Q9NVF7
SYVERRRAPLYFQTL

FAT3

3936

Q8TDW7
ISERDPYLVSYLRQQ

CARD8

521

Q9Y2G2
YYADARLEVGSTQLR

APOL3

46

O95236
APSEYRYTLLRDRDE

ERP44

391

Q9BS26
AVLSNPDKRLRYDEY

DNAJC18

131

Q9H819
TQRRYGSIYTLRLDP

KLHDC9

156

Q8NEP7
LDDYDAGRYSPRLLT

CACTIN

551

Q8WUQ7
RLVNIAVDERSSPYY

CRTAC1

91

Q9NQ79
AVDERSSPYYALRDR

CRTAC1

96

Q9NQ79
RYLITATLTPERDAY

EMILIN2

951

Q9BXX0
DNGDSIPYTINRYLR

ERCC6L2

121

Q5T890
SLRAIRYEISPDREY

DPP6

186

P42658
YFLSTEDLPRRRQLY

DPP6

501

P42658
PYQERLLAEYQRSSS

HELZ2

136

Q9BYK8
GLLYYNRALDRETRS

CDH17

76

Q12864
LYSAVIVYDERSPRA

DUSP4

101

Q13115
LRRSNYVTPKNYLDF

DNAH10

3011

Q8IVF4
PKDLRLYDAYVNRNS

EFCAB3

391

Q8N7B9
DANSYIDTLRKYTRP

PIWIL3

551

Q7Z3Z3
TYIQSRFYRAPEVIL

DYRK2

381

Q92630
KRDRLVNEPLAAYSY

ATP4A

851

P20648
PFYSNISKDRRYADL

PGAM1

131

P18669
DRYIAISQPLRYVTI

OR4D1

121

Q15615
RYSAPANLYVRELRE

PTPRD

216

P23468
NYLLYVFAPDRESRQ

ITK

86

Q08881
YTYLRPRNLRSPAED

OR2L13

256

Q8N349
PSRQALLIERYYAFD

FIBP

86

O43427
PAADNYEETLSTLRY

KIF13A

331

Q9H1H9
NLSYRLDAEVPTRYR

PKP1

481

Q13835
NRPRDSQLYAVDYET

MRPS34

26

P82930
YPSLILSDNLRQVRY

TRIM27

326

P14373
DIVELYPRNVRQYAS

TMC3

916

Q7Z5M5
SRYFLRQPQVYTLDL

RNF183

106

Q96D59
PSLAEAVYSVYRERS

TMEM200C

316

A6NKL6
IVARYIRISPTRAYN

F5

2036

P12259
QEEYDRLRTLSYPQT

RHOG

61

P84095
YSRAYINFRNPDDIL

UPF3A

111

Q9H1J1
EAQYDLRGARSYPTL

PIP5K1C

486

O60331
LTERAYYRSQRPSLE

PPP1R3E

21

Q9H7J1
VSLDSPSYVLYRDRA

FNTA

56

P49354
PEGYRVSQALRENTY

FAF2

216

Q96CS3
SASYYLNQLERITDP

GNAT2

151

P19087
YESLKERRYLPLSQA

MTR

921

Q99707
NEARLRNLTYSAPLY

POLR2B

111

P30876
APQRLLYYDVSTARD

TRGV3

61

P03979
VEQLLYESPERYSRS

TAP1

681

Q03518
AYSRSLPRLYRATEN

PHLDB2

251

Q86SQ0
NYVVPRVDYISTRRA

SVEP1

131

Q4LDE5
ELYQRCLDSAYDPRI

OCRL

806

Q01968
SPLEASRGIDYYDRN

SLC12A4

51

Q9UP95
LGYRPVYSEDEQRNL

CHST6

356

Q9GZX3
EALTRYLRAALAPYN

CLEC11A

221

Q9Y240
YATPTRDSNDKLRYF

TECTA

1981

O75443
DALYSRQRYVLGDTA

UBA6

41

A0AVT1
DLYTDSEPRATYRRQ

SPATA2

336

Q9UM82
SYRAILRYLTNEREP

ZBTB11

6

O95625
TDATLNRLLYNSPEY

TICRR

281

Q7Z2Z1
YYNSSERALAPLRDP

TRIM11

386

Q96F44
YAADVRLDPDTAYSR

TRIM68

301

Q6AZZ1
SARAYYERALQLVPD

TMTC1

841

Q8IUR5
RLDPDAYLLDLYRAN

ARHGAP40

596

Q5TG30
YTATRYEFRSIPDIR

SEMA4G

181

Q9NTN9
LQRYSEDRIGLADYA

SUN2

536

Q9UH99
YRLAIQSFASARPYL

RLF

101

Q13129
SFRERYYLSVLQQPT

RIPOR3

351

Q96MK2
VYRYLARLDSDVSPL

ROPN1L

171

Q96C74
ADVTIRQSYRLIYPR

GTF2B

281

Q00403
EYYGQRSRSREPLTD

ILDR2

476

Q71H61
YARGRPDSLLAYLEQ

VPS18

671

Q9P253
LRSYNRHTLVADPYE

SLC9A1

646

P19634
SEELPLYYRRSVELN

TTC14

226

Q96N46
QSYDLDYPERRAISP

UNC13B

241

O14795
RAADKLAPAQYIRYT

SNW1

166

Q13573
RYSESLLGVPIAYDN

POLR1F

81

Q3B726
QLGRQLRYYRESADP

PLEC

1341

Q15149
EPRKRFTYSQDYLSA

nan

441

Q6ZUG5
IQRDDPALATYYGSL

RIOX2

66

Q8IUF8
QLTRIYPSAYRIDSS

PLCH1

651

Q4KWH8
YSRPYTDNRARESSD

SETD2

446

Q9BYW2
QRSELPRESSYDIYR

TJP3

351

O95049
RTYRKDQPRDYSGEN

ZNF155

496

Q12901
APQRLLYYDSYNSRV

TRGV8

61

A0A0C4DH27
YRYEINADPRLTNLS

TPBG

401

Q13641
PRLDLEDSYTLRGSY

TASOR2

1841

Q5VWN6
NYPRVRTSAAYLLVS

USP34

2676

Q70CQ2
LDTGNRPREAYTEYL

VPS9D1

26

Q9Y2B5
TAKRYNLDDYRTPVF

UBR4

4316

Q5T4S7
PISRYYDRLATVQAR

TRRAP

3611

Q9Y4A5
AENDTPYYDVSRNAR

VIP

66

P01282
PAQRALYREVTLENY

ZNF337

31

Q9Y3M9