Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionprotein-L-isoaspartate (D-aspartate) O-methyltransferase activity

PCMTD2 PCMTD1 PCMT1

6.89e-093393GO:0004719
GeneOntologyMolecularFunctionsolute:sodium symporter activity

SLC6A5 SLC4A10 SLC5A10 SLC4A4 SLC6A20 SLC5A3

1.08e-0881396GO:0015370
GeneOntologyMolecularFunctionsymporter activity

SLC6A5 SLC4A10 SLC5A10 SLC4A4 SLC4A11 SLC6A20 SLC5A3

1.47e-08150397GO:0015293
GeneOntologyMolecularFunctionsodium ion transmembrane transporter activity

SLC6A5 SLC4A10 SLC5A10 SLC4A4 SLC4A11 SLC6A20 SLC5A3

3.65e-08171397GO:0015081
GeneOntologyMolecularFunctionsecondary active transmembrane transporter activity

SLC6A5 SLC4A10 SLC26A9 SLC5A10 SLC4A4 SLC4A11 SLC6A20 SLC5A3

8.76e-08296398GO:0015291
GeneOntologyMolecularFunctionsolute:monoatomic cation symporter activity

SLC6A5 SLC4A10 SLC5A10 SLC4A4 SLC6A20 SLC5A3

1.10e-07119396GO:0015294
GeneOntologyMolecularFunctioncarboxyl-O-methyltransferase activity

PCMTD2 PCMTD1 PCMT1

2.40e-077393GO:0010340
GeneOntologyMolecularFunctionprotein carboxyl O-methyltransferase activity

PCMTD2 PCMTD1 PCMT1

2.40e-077393GO:0051998
GeneOntologyMolecularFunctionbicarbonate transmembrane transporter activity

SLC4A10 SLC26A9 SLC4A4 SLC4A11

4.29e-0732394GO:0015106
GeneOntologyMolecularFunctionsolute:inorganic anion antiporter activity

SLC4A10 SLC26A9 SLC4A4 SLC4A11

4.29e-0732394GO:0005452
GeneOntologyMolecularFunctionactive monoatomic ion transmembrane transporter activity

SLC6A5 SLC4A10 SLC26A9 SLC5A10 SLC4A4 SLC6A20 SLC5A3

1.68e-06301397GO:0022853
GeneOntologyMolecularFunctionactive transmembrane transporter activity

SLC6A5 SLC4A10 SLC26A9 SLC5A10 SLC4A4 SLC4A11 SLC6A20 SLC5A3

3.21e-06477398GO:0022804
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

SLC6A5 TMEM63B SLC4A10 SLC26A9 SLC5A10 SLC4A4 SLC4A11 SLC6A20 SLC5A3

1.19e-05758399GO:0015318
GeneOntologyMolecularFunctionO-methyltransferase activity

PCMTD2 PCMTD1 PCMT1

1.54e-0525393GO:0008171
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

SLC6A5 TMEM63B SLC4A10 SLC26A9 SLC5A10 SLC4A4 SLC4A11 SLC6A20 SLC5A3

1.70e-05793399GO:0015075
GeneOntologyMolecularFunctionorganic anion transmembrane transporter activity

SLC6A5 SLC4A10 SLC26A9 SLC4A4 SLC4A11 SLC6A20

2.06e-05293396GO:0008514
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

SLC6A5 TMEM63B SLC4A10 SLC5A10 SLC4A4 SLC4A11 SLC6A20 SLC5A3

2.35e-05627398GO:0022890
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

SLC6A5 SLC4A10 SLC5A10 SLC4A4 SLC4A11 SLC6A20 SLC5A3

2.86e-05465397GO:0046873
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

SLC6A5 TMEM63B SLC4A10 SLC5A10 SLC4A4 SLC4A11 SLC6A20 SLC5A3

3.54e-05664398GO:0008324
GeneOntologyMolecularFunctionsodium:bicarbonate symporter activity

SLC4A10 SLC4A4

5.55e-056392GO:0008510
GeneOntologyMolecularFunctionD-glucose:sodium symporter activity

SLC5A10 SLC5A3

7.76e-057392GO:0005412
GeneOntologyMolecularFunctionantiporter activity

SLC4A10 SLC26A9 SLC4A4 SLC4A11

1.49e-04138394GO:0015297
GeneOntologyMolecularFunctionchloride:bicarbonate antiporter activity

SLC4A10 SLC26A9

2.86e-0413392GO:0140900
GeneOntologyMolecularFunctionbicarbonate:monoatomic anion antiporter activity

SLC4A10 SLC26A9

2.86e-0413392GO:0140829
GeneOntologyMolecularFunctionmonoatomic cation:bicarbonate symporter activity

SLC4A10 SLC4A4

2.86e-0413392GO:0140410
GeneOntologyMolecularFunctioninorganic anion transmembrane transporter activity

SLC4A10 SLC26A9 SLC4A4 SLC4A11

3.38e-04171394GO:0015103
GeneOntologyMolecularFunctiontransmembrane transporter activity

SLC6A5 TMEM63B SLC4A10 SLC26A9 SLC5A10 SLC4A4 SLC4A11 SLC6A20 SLC5A3

3.60e-041180399GO:0022857
GeneOntologyMolecularFunctioncarbohydrate:monoatomic cation symporter activity

SLC5A10 SLC5A3

4.96e-0417392GO:0005402
GeneOntologyMolecularFunctiontransporter activity

SLC6A5 TMEM63B SLC4A10 SLC26A9 SLC5A10 SLC4A4 SLC4A11 SLC6A20 SLC5A3

6.87e-041289399GO:0005215
GeneOntologyMolecularFunctionamino acid:sodium symporter activity

SLC6A5 SLC6A20

9.16e-0423392GO:0005283
GeneOntologyMolecularFunctionprotein methyltransferase activity

PCMTD2 PCMTD1 PCMT1

1.06e-03103393GO:0008276
GeneOntologyMolecularFunctionD-glucose transmembrane transporter activity

SLC5A10 SLC5A3

1.08e-0325392GO:0055056
GeneOntologyMolecularFunctionhexose transmembrane transporter activity

SLC5A10 SLC5A3

1.08e-0325392GO:0015149
GeneOntologyMolecularFunctionmonosaccharide transmembrane transporter activity

SLC5A10 SLC5A3

1.27e-0327392GO:0015145
GeneOntologyMolecularFunctionamino acid:monoatomic cation symporter activity

SLC6A5 SLC6A20

1.46e-0329392GO:0005416
GeneOntologyMolecularFunctionsugar transmembrane transporter activity

SLC5A10 SLC5A3

1.46e-0329392GO:0051119
GeneOntologyMolecularFunctionorganic acid:sodium symporter activity

SLC6A5 SLC6A20

2.12e-0335392GO:0005343
GeneOntologyMolecularFunctionneutral L-amino acid transmembrane transporter activity

SLC6A5 SLC6A20

2.90e-0341392GO:0015175
GeneOntologyMolecularFunctioncarbohydrate transmembrane transporter activity

SLC5A10 SLC5A3

3.05e-0342392GO:0015144
GeneOntologyMolecularFunctionmonoatomic anion transmembrane transporter activity

SLC4A10 SLC26A9 SLC4A4

3.17e-03151393GO:0008509
GeneOntologyMolecularFunctionS-adenosylmethionine-dependent methyltransferase activity

PCMTD2 PCMTD1 PCMT1

4.57e-03172393GO:0008757
GeneOntologyMolecularFunctioncarboxylic acid transmembrane transporter activity

SLC6A5 SLC26A9 SLC6A20

7.63e-03207393GO:0046943
GeneOntologyMolecularFunctionorganic acid transmembrane transporter activity

SLC6A5 SLC26A9 SLC6A20

7.73e-03208393GO:0005342
GeneOntologyMolecularFunctionmethyltransferase activity

PCMTD2 PCMTD1 PCMT1

8.25e-03213393GO:0008168
GeneOntologyMolecularFunctionL-amino acid transmembrane transporter activity

SLC6A5 SLC6A20

8.48e-0371392GO:0015179
GeneOntologyMolecularFunctiontransferase activity, transferring one-carbon groups

PCMTD2 PCMTD1 PCMT1

9.46e-03224393GO:0016741
GeneOntologyMolecularFunctiondouble-stranded RNA binding

A1CF STRBP

1.02e-0278392GO:0003725
GeneOntologyMolecularFunctionorganic cation transmembrane transporter activity

SLC6A5 SLC6A20

1.14e-0283392GO:0015101
GeneOntologyMolecularFunctionSMAD binding

GATA4 USP15

1.23e-0286392GO:0046332
GeneOntologyBiologicalProcesssodium ion transmembrane transport

SLC6A5 SLC4A10 SLC5A10 SLC4A4 SLC4A11 SLC6A20 SLC5A3

7.64e-08208377GO:0035725
GeneOntologyBiologicalProcesssodium ion transport

SLC6A5 SLC4A10 SLC5A10 SLC4A4 SLC4A11 SLC6A20 SLC5A3

5.07e-07275377GO:0006814
GeneOntologyBiologicalProcessbicarbonate transport

SLC4A10 SLC26A9 SLC4A4 SLC4A11

6.19e-0738374GO:0015701
GeneOntologyBiologicalProcesscellular response to osmotic stress

SERPINB6 DYSF USP15 SLC4A11

8.26e-0672374GO:0071470
GeneOntologyBiologicalProcessmonoatomic ion transmembrane transport

SLC6A5 TMEM63B SLC4A10 SLC26A9 SLC5A10 SLC4A4 DYSF SLC4A11 SLC6A20 SLC5A3

1.87e-0511153710GO:0034220
GeneOntologyBiologicalProcessmonoatomic cation transmembrane transport

SLC6A5 TMEM63B SLC4A10 SLC5A10 SLC4A4 DYSF SLC4A11 SLC6A20 SLC5A3

3.26e-05942379GO:0098655
GeneOntologyBiologicalProcessglycine import across plasma membrane

SLC6A5 SLC6A20

4.68e-056372GO:1903804
GeneOntologyBiologicalProcessresponse to osmotic stress

SERPINB6 DYSF USP15 SLC4A11

4.91e-05113374GO:0006970
GeneOntologyBiologicalProcessinorganic ion transmembrane transport

SLC6A5 SLC4A10 SLC26A9 SLC5A10 SLC4A4 DYSF SLC4A11 SLC6A20 SLC5A3

5.92e-051017379GO:0098660
GeneOntologyBiologicalProcessmonoatomic ion transport

SLC6A5 TMEM63B SLC4A10 SLC26A9 SLC5A10 SLC4A4 DYSF SLC4A11 SLC6A20 SLC5A3

1.10e-0413743710GO:0006811
GeneOntologyBiologicalProcessmonoatomic cation transport

SLC6A5 TMEM63B SLC4A10 SLC5A10 SLC4A4 DYSF SLC4A11 SLC6A20 SLC5A3

1.59e-041157379GO:0006812
GeneOntologyBiologicalProcessinorganic cation transmembrane transport

SLC6A5 SLC4A10 SLC5A10 SLC4A4 DYSF SLC4A11 SLC6A20 SLC5A3

1.88e-04922378GO:0098662
GeneOntologyBiologicalProcessorganic anion transport

SLC6A5 SLC4A10 SLC26A9 SLC4A4 SLC4A11 SLC6A20

2.83e-04515376GO:0015711
GeneOntologyBiologicalProcessinorganic anion transport

SLC4A10 SLC26A9 SLC4A4 SLC4A11

2.96e-04180374GO:0015698
GeneOntologyBiologicalProcessmonoatomic anion transport

SLC4A10 SLC26A9 SLC4A4 SLC4A11

3.15e-04183374GO:0006820
GeneOntologyBiologicalProcessglycine transport

SLC6A5 SLC6A20

3.24e-0415372GO:0015816
GeneOntologyBiologicalProcessmetal ion transport

SLC6A5 SLC4A10 SLC5A10 SLC4A4 DYSF SLC4A11 SLC6A20 SLC5A3

3.26e-041000378GO:0030001
GeneOntologyBiologicalProcesstransport across blood-brain barrier

SLC4A4 SLC6A20 SLC5A3

5.08e-0487373GO:0150104
GeneOntologyBiologicalProcessvascular transport

SLC4A4 SLC6A20 SLC5A3

5.25e-0488373GO:0010232
GeneOntologyCellularComponentapical plasma membrane

SLC4A10 SLC26A9 SLC5A10 FZD3 SLC4A11 SLC6A20 SLC5A3

3.42e-05487407GO:0016324
GeneOntologyCellularComponentapical part of cell

SLC4A10 SLC26A9 SLC5A10 FZD3 SLC4A11 SLC6A20 SLC5A3

1.17e-04592407GO:0045177
GeneOntologyCellularComponentbasolateral plasma membrane

SLC4A10 SLC4A4 PCMT1 SLC4A11 SLC5A3

3.45e-04320405GO:0016323
GeneOntologyCellularComponentbasal plasma membrane

SLC4A10 SLC4A4 PCMT1 SLC4A11 SLC5A3

5.47e-04354405GO:0009925
GeneOntologyCellularComponentbasal part of cell

SLC4A10 SLC4A4 PCMT1 SLC4A11 SLC5A3

7.36e-04378405GO:0045178
DomainPCMT

PCMTD2 PCMTD1 PCMT1

6.58e-093363IPR000682
DomainPCMT

PCMTD2 PCMTD1 PCMT1

6.58e-093363PS01279
DomainPTrfase/Anion_transptr

SLC4A10 SLC4A4 SLC4A11

7.82e-0710363IPR016152
DomainHCO3_cotransp

SLC4A10 SLC4A4 SLC4A11

7.82e-0710363PF00955
DomainHCO3_transpt_euk

SLC4A10 SLC4A4 SLC4A11

7.82e-0710363IPR003020
DomainHCO3_transpt_C

SLC4A10 SLC4A4 SLC4A11

7.82e-0710363IPR011531
DomainNa/HCO3_transpt

SLC4A10 SLC4A4

3.60e-055362IPR003024
DomainNa/solute_symporter_CS

SLC5A10 SLC5A3

1.00e-048362IPR018212
DomainBand3_cytoplasmic_dom

SLC4A10 SLC4A4

1.29e-049362IPR013769
DomainBand_3_cyto

SLC4A10 SLC4A4

1.29e-049362PF07565
Domain-

SLC4A10 SLC4A4

1.29e-0493623.40.1100.10
DomainNA_SOLUT_SYMP_2

SLC5A10 SLC5A3

2.36e-0412362PS00457
DomainSSF

SLC5A10 SLC5A3

2.36e-0412362PF00474
DomainNa/solute_symporter

SLC5A10 SLC5A3

2.36e-0412362IPR001734
DomainNA_SOLUT_SYMP_3

SLC5A10 SLC5A3

2.36e-0412362PS50283
DomainUbiquitin-rel_dom

RGL1 UBXN11 FRMPD3 USP15

4.20e-04184364IPR029071
DomainSH3_9

ARHGEF38 TNK2 ARHGAP26

4.53e-0478363PF14604
DomainNA_NEUROTRAN_SYMP_2

SLC6A5 SLC6A20

5.42e-0418362PS00754
DomainNA_NEUROTRAN_SYMP_3

SLC6A5 SLC6A20

6.05e-0419362PS50267
DomainSNF

SLC6A5 SLC6A20

6.05e-0419362PF00209
DomainNa/ntran_symport

SLC6A5 SLC6A20

6.05e-0419362IPR000175
DomainNA_NEUROTRAN_SYMP_1

SLC6A5 SLC6A20

6.05e-0419362PS00610
Domain-

A1CF STRBP

1.23e-03273623.30.160.20
DomaindsRBD_dom

A1CF STRBP

1.32e-0328362IPR014720
Domain-

PCMTD2 PCMTD1 PCMT1

1.58e-031203633.40.50.150
DomainSAM-dependent_MTases

PCMTD2 PCMTD1 PCMT1

1.66e-03122363IPR029063
DomainSH3

ARHGEF38 TNK2 ARHGAP26

8.22e-03216363PS50002
DomainSH3

ARHGEF38 TNK2 ARHGAP26

8.22e-03216363SM00326
DomainSH3_domain

ARHGEF38 TNK2 ARHGAP26

8.65e-03220363IPR001452
PathwayREACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

SLC6A5 SLC4A10 SLC26A9 SLC5A10 SLC4A4 SLC6A20 SLC5A3

1.79e-07238267MM15076
PathwayREACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

SLC6A5 SLC4A10 SLC26A9 SLC5A10 SLC4A4 SLC6A20 SLC5A3

2.44e-07249267M5988
PathwayREACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES

SLC4A10 SLC26A9 SLC4A4 SLC6A20

4.28e-05108264M823
PathwayREACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES

SLC4A10 SLC26A9 SLC4A4 SLC6A20

4.43e-05109264MM15074
PathwayWP_NRF2_PATHWAY

SLC6A5 SLC5A10 SLC6A20 SLC5A3

1.21e-04141264M39454
PathwayREACTOME_BICARBONATE_TRANSPORTERS

SLC4A10 SLC4A4

1.46e-0410262M27335
PathwayREACTOME_BICARBONATE_TRANSPORTERS

SLC4A10 SLC4A4

1.46e-0410262MM15073
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

SLC6A5 SLC4A10 SLC26A9 SLC5A10 SLC4A4 SLC6A20 SLC5A3

1.75e-04681267MM14985
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

SLC6A5 SLC4A10 SLC26A9 SLC5A10 SLC4A4 SLC6A20 SLC5A3

2.82e-04736267M27287
PathwayREACTOME_TRANSPORT_OF_BILE_SALTS_AND_ORGANIC_ACIDS_METAL_IONS_AND_AMINE_COMPOUNDS

SLC6A5 SLC6A20 SLC5A3

3.58e-0476263MM15072
PathwayREACTOME_TRANSPORT_OF_BILE_SALTS_AND_ORGANIC_ACIDS_METAL_IONS_AND_AMINE_COMPOUNDS

SLC6A5 SLC6A20 SLC5A3

4.81e-0484263M27334
PathwayREACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS

SLC6A5 SLC6A20

5.49e-0419262MM15107
PathwayREACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS

SLC6A5 SLC6A20

5.49e-0419262M27362
PathwayREACTOME_SLC_TRANSPORTER_DISORDERS

SLC6A5 SLC4A4 SLC6A20

7.77e-0499263M27474
PathwayWP_NUCLEAR_RECEPTORS_METAPATHWAY

SLC6A5 SLC5A10 SLC6A20 SLC5A3

2.45e-03314264M39428
Pubmed

Distinct expression and function of alternatively spliced Tbx5 isoforms in cell growth and differentiation.

GATA4 A1CF

3.87e-06340218391012
Pubmed

Human Protein-l-isoaspartate O-Methyltransferase Domain-Containing Protein 1 (PCMTD1) Associates with Cullin-RING Ligase Proteins.

PCMTD1 PCMT1

3.87e-06340235486881
Pubmed

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.

GATA4 SMPD4 UTP20 RIF1 HUWE1 CAMSAP1 FOXR2 STRBP

5.03e-0685740825609649
Pubmed

A context-specific cardiac β-catenin and GATA4 interaction influences TCF7L2 occupancy and remodels chromatin driving disease progression in the adult heart.

GATA4 A1CF

7.73e-06440229394407
Pubmed

The E3 ligase Mule protects the heart against oxidative stress and mitochondrial dysfunction through Myc-dependent inactivation of Pgc-1α and Pink1.

A1CF HUWE1

1.29e-05540228148912
Pubmed

The variant Polycomb Repressor Complex 1 component PCGF1 interacts with a pluripotency sub-network that includes DPPA4, a regulator of embryogenesis.

PCMTD2 HUWE1 PCMTD1 USP15 PCMT1

8.85e-0539640526687479
Pubmed

Insulin receptor substrate-4 interacts with ubiquitin-specific protease 18 to activate the Jak/STAT signaling pathway.

EEF2 HUWE1

9.98e-051340229285303
Pubmed

Proteomic analysis identifies novel binding partners of BAP1.

EEF2 HUWE1 PCMT1

1.09e-048040334591877
Pubmed

Large-scale proteomics and phosphoproteomics of urinary exosomes.

DNHD1 EEF2 SERPINB6 SLC5A10 HUWE1 SLC4A4 DYSF

1.43e-04101640719056867
Pubmed

A cascading activity-based probe sequentially targets E1-E2-E3 ubiquitin enzymes.

EEF2 USP15 PCMT1

1.45e-048840327182664
Pubmed

Distinct roles for cell-autonomous Notch signaling in cardiomyocytes of the embryonic and adult heart.

GATA4 A1CF

1.53e-041640220007915
Pubmed

Interactome analyses revealed that the U1 snRNP machinery overlaps extensively with the RNAP II machinery and contains multiple ALS/SMA-causative proteins.

RIF1 PCMTD1 STRBP PCMT1

1.77e-0424440429884807
Pubmed

USP15 Enhances Re-epithelialization Through Deubiquitinating EIF4A1 During Cutaneous Wound Repair.

EEF2 USP15

1.95e-041840232671073
Pubmed

A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex.

SMPD4 RIF1 CRYBG3 CAMSAP1 PCMT1

2.00e-0447240538943005
Pubmed

Tissue-Specific Regulation of the Wnt/β-Catenin Pathway by PAGE4 Inhibition of Tankyrase.

RIF1 EEF2 HUWE1 USP15

2.13e-0425640432698014
Pubmed

A microRNA-Hippo pathway that promotes cardiomyocyte proliferation and cardiac regeneration in mice.

GATA4 A1CF

2.18e-041940225787764
Pubmed

An Interaction Landscape of Ubiquitin Signaling.

TNK2 PCMTD2 HUWE1 PCMTD1 USP15

2.19e-0448140528190767
Pubmed

Blood-Brain Barrier: From Physiology to Disease and Back.

SLC4A4 SLC6A20 SLC5A3

2.44e-0410540330280653
Pubmed

The repertoire of solute carriers of family 6: identification of new human and rodent genes.

SLC6A5 SLC6A20

2.67e-042140216125675
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

SLC4A10 SERPINB6 CRYBG3 HUWE1 SLC4A4 CAMSAP1 USP15

2.87e-04113940736417873
Pubmed

Virus-Host Interactome and Proteomic Survey Reveal Potential Virulence Factors Influencing SARS-CoV-2 Pathogenesis.

UTP20 SERPINB6 CAMSAP1 PCMT1

3.20e-0428540432838362
Pubmed

C16orf72/HAPSTR1 is a molecular rheostat in an integrated network of stress response pathways.

RIF1 HUWE1 USP15

3.52e-0411940335776542
Pubmed

A promiscuous biotin ligase fusion protein identifies proximal and interacting proteins in mammalian cells.

RIF1 USP15 PCMT1

3.69e-0412140322412018
Pubmed

Unconventional myosin VI in the heart: Involvement in cardiac dysfunction progressing with age.

GATA4 DYSF

4.45e-042740237169038
Pubmed

USP14 is a deubiquitinase for Ku70 and critical determinant of non-homologous end joining repair in autophagy and PTEN-deficient cells.

RIF1 USP15

5.50e-043040231740976
Pubmed

Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.

RIF1 EEF2 SERPINB6 HUWE1

5.68e-0433240432786267
Pubmed

Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.

GATA4 RIF1 HUWE1 USP15 ARHGAP26 PCMT1

5.87e-0491640632203420
Pubmed

Tagging genes with cassette-exchange sites.

RIF1 DYSF STRBP ARHGAP26

5.88e-0433540415741177
Pubmed

Splicing Regulator p54nrb /Non-POU Domain-Containing Octamer-Binding Protein Enhances Carcinogenesis Through Oncogenic Isoform Switch of MYC Box-Dependent Interacting Protein 1 in Hepatocellular Carcinoma.

SMPD4 EEF2

6.26e-043240231815296
Pubmed

Alterations in the brain interactome of the intrinsically disordered N-terminal domain of the cellular prion protein (PrPC) in Alzheimer's disease.

SLC4A10 EEF2 SERPINB6 SLC4A4

6.28e-0434140429791485
Pubmed

MYC multimers shield stalled replication forks from RNA polymerase.

UTP20 RIF1 EEF2 HUWE1 STRBP PCMT1

8.75e-0498940636424410
Pubmed

SARS-CoV-2 Nsp6 damages Drosophila heart and mouse cardiomyocytes through MGA/MAX complex-mediated increased glycolysis.

SMPD4 RIF1 EEF2 HUWE1 USP15

9.02e-0465740536180527
Pubmed

Quantitative Lys-ϵ-Gly-Gly (diGly) proteomics coupled with inducible RNAi reveals ubiquitin-mediated proteolysis of DNA damage-inducible transcript 4 (DDIT4) by the E3 ligase HUWE1.

EEF2 HUWE1 USP15 PCMT1

9.12e-0437740425147182
GeneFamilySolute carriers

SLC6A5 SLC4A10 SLC26A9 SLC5A10 SLC4A4 SLC4A11 SLC6A20 SLC5A3

1.18e-08395228752
GeneFamilyPDZ domain containing

FRMPD3 MAST3

1.45e-021522221220
ToppCell5'-Adult-SmallIntestine-Epithelial-Tuft-related-Microfold_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GATA4 SLC26A9 SERPINB6 SLC4A4 SLC4A11

5.88e-071863956d8dd6d0403d149cb6edb346581fe6c248036785
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC26A9 A1CF SLC5A10 SLC6A20

1.91e-051823944a9c13932e7163fd37a3dcc4c6ca3bbea5372459
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

RGL1 A1CF SLC5A10 SLC6A20

2.08e-05186394a417e1e21313a7e05951038cdef5ac672a9f727c
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2-D231|Adult / Lineage, Cell type, age group and donor

ARHGEF38 SLC26A9 SLC4A4 SLC6A20

2.21e-05189394dab54a52358f66a8a9460cd6089a06c5fa7e7a5d
ToppCellCOVID-19-lung-AT2|lung / Disease (COVID-19 only), tissue and cell type

ARHGEF38 TMEM63B SLC26A9 SLC4A4

2.30e-05191394276455a64c2c3503d5048615762eb2ee37f0ac70
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SLC4A10 FZD3 STRBP ARHGAP26

2.50e-051953942e1df01bf6e4e98e6cd9fb50926e34c5077b8666
ToppCellTracheal-NucSeq-Epithelial-Epi_airway_neuro-secretory-Neuroendocrine|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SLC6A5 GATA4 SLC26A9 A1CF

2.55e-0519639495544097577f20ed7f4144bd940471cde0617554
ToppCell3'-GW_trimst-1.5-SmallIntestine-Epithelial-epithelial_progenitor_cell|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ARHGEF38 GATA4 A1CF SLC6A20

2.60e-05197394f097e729f515e7945b9482e9f9dbc9536b90f0bb
ToppCellBiopsy_Other_PF-Epithelial-AT2|Biopsy_Other_PF / Sample group, Lineage and Cell type

ARHGEF38 TMEM63B SLC26A9 SLC4A4

2.71e-051993949a65acfe9bf500db72142469cf17bf0973540001
ToppCell5'-GW_trimst-1.5-SmallIntestine-Epithelial-epithelial_progenitor_cell-TA|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ARHGEF38 GATA4 A1CF SLC6A20

2.71e-05199394c9bd712cf401aec256a2cfaec5b580209e52c265
ToppCell5'-GW_trimst-1.5-SmallIntestine-Epithelial-epithelial_progenitor_cell|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ARHGEF38 GATA4 A1CF SLC6A20

2.76e-05200394eef5f6bd9ff5d985def8befcf45786234317f144
ToppCellHippocampus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Sfrp2-Inhibitory_Neuron.Gad1Gad2_Id2.Sfrp2_(Interneuron,_Neurogliaform1)|Hippocampus / BrainAtlas - Mouse McCarroll V32

SLC26A9 CCDC168 DYSF

3.59e-0573393cc89c94a3768b02036757dea86989d9284b214b9
ToppCellHippocampus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Sfrp2|Hippocampus / BrainAtlas - Mouse McCarroll V32

SLC26A9 CCDC168 DYSF

3.59e-05733936f28d52700bab981c8a3664ba4762f3572f7e788
ToppCellHippocampus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Sfrp2-Inhibitory_Neuron.Gad1Gad2_Id2.Sfrp2_(Interneuron,_Neurogliaform1)-|Hippocampus / BrainAtlas - Mouse McCarroll V32

SLC26A9 CCDC168 DYSF

3.59e-0573393ae80fcf3544c18fe0318a8311e96f2448f7cb03c
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-1M-Neuronal-ventral_progenitors_and_neurons_3|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.

CCDC168 A1CF FRMPD3

2.70e-04144393ce5e219f2548b51440b8b3e1a9f011afd4510d19
ToppCellTCGA-Head_and_Esophagus-Primary_Tumor-Esophageal_Carcinoma-Adenocarcinoma-3|TCGA-Head_and_Esophagus / Sample_Type by Project: Shred V9

ARHGEF38 A1CF SLC6A20

2.81e-04146393e55b4acecf4e363b5afa287c747c2e58c4597f3a
ToppCellTCGA-Cervix-Primary_Tumor-Endocervical_Adenocarcinoma-Mucinous_Adenocarcinoma-7|TCGA-Cervix / Sample_Type by Project: Shred V9

ARHGEF38 ARHGAP26 SLC6A20

3.60e-0415939375a82bbabd97b168dbf1c3f43a9bdad48ce18c78
ToppCellHealthy_Control-Lymphoid-T-innate_T|Healthy_Control / Condition, Lineage, Cell class and cell subclass

SLC4A10 SLC4A4 SLC6A20

4.02e-041653931ade67229b50fe20eb392262a3e1ee4306b73290
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

A1CF SLC5A10 SLC4A4

4.23e-04168393fa0d251693935116adf633d02b7ec4a295100865
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Myeloid-Monocytic-Nonclassical_Monocyte-Mono_c5-CD16|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

RGL1 CAMSAP1 SLC5A3

4.46e-0417139387d652afbb375f8ee50e5faecf6085630cd2163c
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

A1CF SLC5A10 SLC4A4

4.61e-041733938888434641ea554a9b62c436e87920378eef29cd
ToppCell5'-GW_trimst-1.5-SmallIntestine-Epithelial-epithelial_progenitor_cell-Proximal_progenitor|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ARHGEF38 GATA4 SLC6A20

4.77e-041753936759d200a133034756de9cdf2d5daceca927aac9
ToppCellCaecum-Dendritic_cell-cDC1|Dendritic_cell / Region, Cell class and subclass

CHIC2 CRYBG3 DYSF

4.85e-0417639307cde50e1c18fcc2c5028efe1a087db4ef4d4783
ToppCellCOVID-19_Mild-Neu_3|COVID-19_Mild / 5 Neutrophil clusters in COVID-19 patients

RGL1 FRMPD3 MAST3

4.85e-041763932049767fd591045cfcf5b1071d80798e52843f27
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SLC26A9 A1CF SLC5A10

4.85e-041763931595dbeee336a81e581325d63208ec6262664ee9
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-nan|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC4A4 FZD3 STRBP

4.85e-041763931dd54bfaa58541de51e5a8328651d390833bd480
ToppCellPBMC-Mild-cDC_11|Mild / Compartment, Disease Groups and Clusters

DYSF FZD3 STRBP

4.93e-04177393974305e4c0eff90134c4e58cf11b955d1eee0501
ToppCelldroplet-Lung-30m-Epithelial-alveolar_epithelial|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ARHGEF38 SLC26A9 SLC4A4

5.01e-0417839376e71fff99cf64302e2e3c0d66dd8ba0ff13624e
ToppCelldroplet-Lung-30m-Epithelial|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ARHGEF38 SLC26A9 SLC4A4

5.01e-041783935442bc52b8e902da1383f44d97a9f95e471a8d4d
ToppCellCOVID-19-kidney-PCT-S1/S2|COVID-19 / Disease (COVID-19 only), tissue and cell type

A1CF SLC5A10 SLC4A4

5.01e-0417839323a12d3d971b857d5be8e907334d1f6b49eeeb32
ToppCelldroplet-Lung-30m-Epithelial-alveolar_epithelial-type_II_pneumocyte-type_2_alveolar_epithelial_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ARHGEF38 SLC26A9 SLC4A4

5.01e-0417839382f78ea1ea3ff3e2347cd8bc2f06e2a10e96f220
ToppCelldroplet-Lung-30m-Epithelial-alveolar_epithelial-type_II_pneumocyte|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ARHGEF38 SLC26A9 SLC4A4

5.01e-04178393523b286ebe0359c7f1902f28cbd71f452626fc0d
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

A1CF SLC5A10 ARHGAP26

5.09e-0417939358ae5a97fe2a14e1c6fdeb886397eb06fdaf0428
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

A1CF SLC5A10 SLC4A4

5.18e-041803931363b3254470f6ff98630d1df83a1bdbacc137e0
ToppCelldroplet-Lung-LUNG-30m-Epithelial-type_II_pneumocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGEF38 SLC26A9 SLC4A4

5.26e-04181393cadb18fc73031eb9f779599e15cd7861337fee78
ToppCelldroplet-Lung-LUNG-30m-Epithelial-Alveolar_Epithelial_Type_2|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGEF38 SLC26A9 SLC4A4

5.26e-0418139385bec4d3f255f4c61c790325eeb50ad38f709ef2
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

A1CF SLC5A10 SLC6A20

5.35e-04182393e1e58176f533092b6b974ca1ce8b02192a6e193d
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

A1CF SLC5A10 SLC6A20

5.35e-0418239357bb5a2da976464ba7c4460106bd9f692008ebd9
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC26A9 SLC5A10 SLC6A20

5.43e-04183393d73cac83cde82665f110baad7cf28db75f9ffe52
ToppCellCOVID-19-kidney-PCT-S1|COVID-19 / Disease (COVID-19 only), tissue and cell type

A1CF SLC5A10 SLC6A20

5.43e-041833936878d14026c3df6aa12e45dfad94b32fa9d9b0b7
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

A1CF SLC5A10 SLC4A4

5.43e-0418339384b64cf728629c3af9a8d2ed15b93adf562c54b8
ToppCelldroplet-Kidney-nan-18m-Epithelial-Epcam____kidney_proximal_convoluted_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

A1CF SLC4A4 SLC6A20

5.52e-04184393c86ed59fed687cdaaf7e9c4418d2e3e2c4111cca
ToppCellCOVID-19-kidney-PCT-S1/S2|kidney / Disease (COVID-19 only), tissue and cell type

A1CF SLC5A10 SLC4A4

5.52e-04184393dc71f22583fc54b89b242cbb602f4bbe86f576ec
ToppCelldroplet-Kidney-nan-18m-Epithelial-kidney_proximal_convoluted_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

A1CF SLC4A4 SLC6A20

5.52e-041843937c256bcfa07c5ff55aad0833e8712b0456b5832b
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)-Goblet_(bronchial)_L.0.4.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ARHGEF38 SLC4A4 SLC4A11

5.52e-0418439301c19a830348ab0b9c02c1546a439de70ee10f97
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.4.3|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TMEM63B SLC26A9 SLC6A20

5.61e-041853937460387f48f33674330bd53b759681b264228f5a
ToppCellpdx-Tumor_cells-T0|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

GATA4 A1CF ARHGAP26

5.61e-041853931d874608aa2062024323512f68889219471b2f00
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

A1CF SLC5A10 SLC4A4

5.69e-041863938287146f0ba415ea04475588117d4668ae00f75c
ToppCell10x3'2.3-week_14-16-Lymphocytic_NK-T_NK-CD56_bright_NK|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

SLC4A10 FRMPD3 SLC4A4

5.69e-04186393e0eeef2b9e06324354c5a11a4c6d4c98546f32af
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ARHGEF38 SLC26A9 SLC4A4

5.69e-04186393acfa68a2afb7d2b51c9b469a1965fe5cc5d5e64e
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

A1CF SLC5A10 SLC4A4

5.78e-0418739371eb26ebf60cb0848e5bf1cd01edccda621aecd8
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

A1CF SLC5A10 SLC4A4

5.97e-0418939313fd07cc408a9486f61a7b2c3a132c52d14b438d
ToppCellPBMC-Mild-cDC_12|Mild / Compartment, Disease Groups and Clusters

ARHGEF38 SLC4A10 UTP20

5.97e-04189393946c95d2ecc36b241f58e8c4ad6455fe47c762fa
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

A1CF SLC5A10 SLC4A4

5.97e-04189393204ab61ae606b2d9be0cb6bf6a83a011740693a8
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial-Lgr5-_amplifying_undifferentiated_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UTP20 SLC4A4 STRBP

6.06e-0419039336e83995021ba16690f84e2077a9e8baec547d05
ToppCellSmart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_monocytic|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

UBXN11 USP15 ARHGAP26

6.06e-0419039300ef6ec71353e42260c0d807d7da65b63154c288
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial-epithelial_cell_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UTP20 SLC4A4 STRBP

6.06e-04190393d26be9e1b676f750e716b91ebc3598fac3735612
ToppCellSmart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

UBXN11 USP15 ARHGAP26

6.06e-0419039318c020ca9a23399214133ec255ab870e0060f2e1
ToppCellCOVID-19-lung-AT2|COVID-19 / Disease (COVID-19 only), tissue and cell type

ARHGEF38 TMEM63B SLC26A9

6.06e-0419039327a1a86620fe9b5ee930d388b32352206485e6d0
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ARHGEF38 SLC4A4 SLC4A11

6.06e-041903933c337374d89e69cc0a78e65a4a7e21db7b050fcd
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ARHGEF38 SLC4A4 SLC4A11

6.06e-0419039323f2ac4da431211084bb6ab0494c2e0b69547cb6
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

ARHGEF38 SLC26A9 SLC6A20

6.24e-04192393cc9911e182a289779a2612bc213daae5607689e7
ToppCellCOVID-19-kidney-Myeloid|kidney / Disease (COVID-19 only), tissue and cell type

DYSF USP15 ARHGAP26

6.24e-04192393441cd1ec171f643b28e1f6f9c04def629cc7391b
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ARHGEF38 SLC26A9 SLC4A4

6.24e-04192393fb2f0e897228f808d9ff734ad05e9b49dc38fa50
ToppCellEpithelial-alveolar_epithelial_cell_type_2|World / Lineage, Cell type, age group and donor

ARHGEF38 SLC26A9 SLC4A4

6.24e-0419239358c3737be7acce39fd2b91d70d6d7b2bbaa4f710
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SLC26A9 A1CF SLC5A10

6.24e-041923933e1a4cb0d83efd502c8613d41a1692bdda5860ed
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FZD3 ARHGAP26 MAST3

6.24e-041923935c7e8b80b44d9ce55c797cdf8267ac5382e26cac
ToppCellSmart-seq2-spleen_(Smart-seq2)-myeloid|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

UBXN11 USP15 ARHGAP26

6.34e-041933935f732598cdb6f3bd519f044a9cc553bd2e8b1052
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2|Adult / Lineage, Cell type, age group and donor

ARHGEF38 SLC26A9 SLC4A4

6.34e-04193393738f4f0a9ddde2432b429ab46838e353b1790589
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT2-AT2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ARHGEF38 SLC26A9 SLC4A4

6.34e-04193393fd4d3c0d7caf8a2fff5b3d901fc28d19a8163cdf
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

UBXN11 USP15 ARHGAP26

6.34e-041933931db487e5f81849740d57cc3e2b5739e8f7581efb
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ARHGEF38 SLC26A9 SLC4A4

6.34e-04193393f3cc7cfdbc164a4ed42f87647111522b7d393bcb
ToppCell10x_3'_v2v3-Neoplastic-Differentiated-like-AC-like-AC-like-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PCMTD2 SLC4A4 FZD3

6.43e-041943938b81f039f5b25d35a4d5a41b27d4d9360ba22f15
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

UBXN11 USP15 ARHGAP26

6.43e-04194393a94f9f7179a5733e3c378ff8b337e288785433a1
ToppCellmild-Myeloid-Neutrophils_1|mild / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

DYSF USP15 ARHGAP26

6.43e-04194393ccd911ce3251cd1c60f1fb2ce00650fbe7a379bb
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

ARHGEF38 SLC26A9 SLC4A4

6.43e-0419439397534c8bba895a7913665e03ae4e5c4a6ad71daf
ToppCell(0)_NK_cells-(0)_NK_CD160pos|(0)_NK_cells / Spleen cell shreds - cell class (v1) and cell subclass (v1)

SLC4A4 PCMTD1 STRBP

6.53e-041953936cbeceb52bb207f3c074e57b5b3f7cfb24fd5877
ToppCellCOVID-19-lung-Macrophage_CD163hi_MERTKhi|lung / Disease (COVID-19 only), tissue and cell type

RGL1 DYSF ARHGAP26

6.53e-04195393148fff8c3c9ba45ec36e98dff1be57e3f8294506
ToppCellfacs-Aorta-Heart-3m-Endothelial-aorta_endothelial_cell|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RGL1 DYSF ARHGAP26

6.53e-041953933969b8d5fcec8ef1831531a781f7bbcebab5a4ba
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.0.3|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TMEM63B SLC26A9 SLC6A20

6.53e-0419539337aa6e4123d37de4de42ca68d3020f2a7686ce02
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ARHGEF38 SLC26A9 SLC6A20

6.63e-041963937e5addaa844e66f8160e05858c341866a80aed23
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC26A9 A1CF SLC5A10

6.63e-041963934ebcaac758ed01d918de9c1cd383a84457b615f3
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SERPINB6 DYSF ARHGAP26

6.63e-04196393b8f89a50114932c08fc5daac4b549adfe9df8e66
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SERPINB6 DYSF ARHGAP26

6.63e-04196393145fcf73deba9638b391a1af6c39fa205dc9829f
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Endothelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SERPINB6 DYSF ARHGAP26

6.63e-041963934cd1e6b7a791e11a40b19f971b7011bd11fe6273
ToppCell3'-GW_trimst-1.5-SmallIntestine-Epithelial-epithelial_progenitor_cell-Stem_cells|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ARHGEF38 GATA4 A1CF

6.63e-041963934deaadb9796b907b7480fb7af5ed76ebad240850
ToppCellCOVID-19-Myeloid-Transitioning_MDM|COVID-19 / group, cell type (main and fine annotations)

RGL1 DYSF ARHGAP26

6.63e-041963934929cfed1f150c1fde4d79cb49895c2ea467a18f
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SERPINB6 DYSF ARHGAP26

6.63e-04196393d0ff1082898d2db47c88d2678466514e9e9193d3
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SERPINB6 DYSF ARHGAP26

6.63e-04196393d37f714d4fb57e958f3738fdda085560813e5bb5
ToppCellBL|World / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DYSF USP15 ARHGAP26

6.73e-041973931acf0191fa0a25cd20bfd9ea7bf727a1555986a1
ToppCellCOVID-19-lung-Macrophage_VCANhi_FCN1hi|lung / Disease (COVID-19 only), tissue and cell type

DYSF USP15 ARHGAP26

6.73e-04197393a0f8a992282a6d64890f5574c7c9741fcb38dadd
ToppCellAT2_cells-HP_01|World / lung cells shred on cell class, cell subclass, sample id

TMEM63B SLC26A9 SLC4A4

6.73e-041973938b5d4e1c33a57c899c51feb9a6f347232f8910a3
ToppCellLPS_anti-TNF-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

TMEM63B FRMPD3 SLC4A11

6.73e-041973933d13a4f2e86422900ee2194e8a1fd1cf9750d5d3
ToppCellCOVID-19-lung-Macrophage_VCANhi_FCN1hi|COVID-19 / Disease (COVID-19 only), tissue and cell type

DYSF USP15 ARHGAP26

6.83e-04198393ea34096bee852a7e996f097fa279381afa8f86ff
ToppCellParenchymal-NucSeq-Epithelial-Epi_alveolar-AT2|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ARHGEF38 SLC26A9 SLC4A4

6.83e-041983932e2a4e1756bba6f4fbe529559a97d2993c890b4b
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SERPINB6 DYSF ARHGAP26

6.83e-041983930a172c6d997c7cfbad34b56e80121bd104dee67d
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SLC4A10 STRBP ARHGAP26

6.83e-041983938ab40fae14fe02e39bc8c8da187a5cd60c787643
ToppCellBronchial-NucSeq-Epithelial-Epi_alveolar-AT2|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ARHGEF38 SLC26A9 SLC4A4

6.83e-04198393f948391296c261c473d339069a6d0f20ccd6f38f
ToppCelldistal-1-Epithelial-Alveolar_Epithelial_Type_2|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

TMEM63B SLC26A9 SLC4A4

6.83e-04198393ce9d6b2a93c7b304414ce1b8b1a09562cf581278
ToppCell10x_3'_v2v3-Neoplastic-Differentiated-like-AC-like|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CHIC2 SLC4A4 FZD3

6.93e-041993936723287924750a2247a07ab6e561066a97b09771
Diseaseanemia (implicated_via_orthology)

SLC4A10 SLC4A4 SLC4A11

9.61e-0715393DOID:2355 (implicated_via_orthology)
Diseasehippocampal CA1 volume

SLC4A10 STRBP PCMT1

3.54e-0548393EFO_0009394
DiseaseMalignant neoplasm of breast

SLC6A5 ARHGEF38 RGL1 UTP20 RIF1 EEF2 DYSF STRBP

6.76e-051074398C0006142
DiseasePapillary Renal Cell Carcinoma

DNHD1 EEF2 SLC5A3

6.50e-04128393C1306837
DiseaseRenal Cell Carcinoma

DNHD1 EEF2 SLC5A3

6.50e-04128393C0007134
DiseaseSarcomatoid Renal Cell Carcinoma

DNHD1 EEF2 SLC5A3

6.50e-04128393C1266043
DiseaseChromophobe Renal Cell Carcinoma

DNHD1 EEF2 SLC5A3

6.50e-04128393C1266042
DiseaseCollecting Duct Carcinoma of the Kidney

DNHD1 EEF2 SLC5A3

6.50e-04128393C1266044
Diseaseheart function measurement

GATA4 SERPINB6

9.30e-0434392EFO_0004311
Diseasehippocampus molecular layer volume

SLC4A10 PCMT1

9.85e-0435392EFO_0009397
DiseaseConventional (Clear Cell) Renal Cell Carcinoma

DNHD1 EEF2 SLC5A3

9.90e-04148393C0279702
Diseasesubiculum volume

SLC4A10 PCMT1

1.49e-0343392EFO_0009399
Diseasevitamin D measurement, COVID-19

SLC4A4 SLC6A20

1.92e-0349392EFO_0004631, MONDO_0100096
DiseaseAdenocarcinoma of lung (disorder)

TNK2 SLC4A4 STRBP

2.55e-03206393C0152013

Protein segments in the cluster

PeptideGeneStartEntry
CVKPPYMLLVGNIIM

ERVK13-1

206

Q9NX77
LNILKYEAVPPMIEM

CRYBG3

1556

Q68DQ2
KLYDILPGMELTPMN

A1CF

421

Q9NQ94
LMIKPIQRVMKYPLL

ARHGEF38

236

Q9NXL2
QVLAEPMTYKLMKPL

DNHD1

1941

Q96M86
PMTYKLMKPLVVEEL

DNHD1

1946

Q96M86
EDMLYAPLVLKPNVM

CAMSAP1

306

Q5T5Y3
RLYGVVLTPPMKMVT

TNK2

191

Q07912
PAYILLMLPSLVVDM

CECR9

81

P0C854
PCLQKLLDYLTRMMP

RGL1

166

Q9NZL6
YMKILLKVGGILVMP

PCMTD1

176

Q96MG8
YMKNLLKVGGILVMP

PCMTD2

176

Q9NV79
RIPIPLMDYILNVMK

HUWE1

761

Q7Z6Z7
LDPGGPMMKLVYKLQ

SMPD4

126

Q9NXE4
GLYMKLHGVPRPLAM

GATA4

296

P43694
YSIPMKILPGMKLDE

FRMPD3

1551

Q5JV73
CPIIVPFGLMYMLLK

TMEM63B

641

Q5T3F8
MMEYVILIEFLPKTP

CHIC2

146

Q9UKJ5
LKNMGPLPVDMARLY

MAST3

456

O60307
LMKYLMALIVGIPSV

FZD3

481

Q9NPG1
LAKYRVGVMKPPEMP

FOXR2

46

Q6PJQ5
DLYLKPIQRTILMMG

EEF2

441

P13639
KIAAGMLLNVIYPPM

CCDC168

1131

Q8NDH2
LKYPMEKVPGARMPV

DYSF

836

O75923
MNLVGPMLNPLIYTL

OR10D3

276

Q8NH80
MDLGIDKVKPYLPMI

UTP20

2656

O75691
IFPLIMIAMIPIRYI

SLC4A11

841

Q8NBS3
GSIKMKPLMGVIYVP

PCMT1

201

P22061
MITMLVLGIYLYPLP

SLC26A9

416

Q7LBE3
IPYLMMLALAGLPIF

SLC6A5

231

Q9Y345
KVMMLVYPEELKPVL

RIF1

941

Q5UIP0
SALKTYLRMLPGPLM

ARHGAP26

451

Q9UNA1
MMGKLPLGVVSPYVK

PPP1R32

1

Q7Z5V6
LPYVGKELNMIIMLP

SERPINB6

221

P35237
KLLPMFIIVVPGMIS

SLC5A3

306

P53794
AYGLPKRMVLLPVMK

STRBP

646

Q96SI9
PYIIMLIVEGMPLLY

SLC6A20

46

Q9NP91
IAYPKLVMELMPIGL

SLC5A10

351

A0PJK1
MTSILKFIPMPVLYG

SLC4A10

926

Q6U841
LEVYLVRMDPLTKPM

USP15

476

Q9Y4E8
VFMAPILKFIPMPVL

SLC4A4

891

Q9Y6R1
EPIPLKLYRNGIMMF

UBXN11

231

Q5T124