Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	opsonin binding	CR1L MEGF10 CFHR4 CFHR3	2.83e-06	25	80	4	GO:0001846
GeneOntologyMolecularFunction	complement binding	CR1L MEGF10 CFHR4 CFHR3	7.89e-06	32	80	4	GO:0001848
GeneOntologyMolecularFunction	complement component C3b binding	CR1L CFHR4 CFHR3	1.33e-05	12	80	3	GO:0001851
GeneOntologyMolecularFunction	endopeptidase activity	ADAMTS10 ADAMTS4 PRSS53 ADAMTS7 ADAM21 PCSK7 TMPRSS2 ADAM33 CAPN15	5.50e-05	430	80	9	GO:0004175
GeneOntologyMolecularFunction	metalloendopeptidase activity	ADAMTS10 ADAMTS4 ADAMTS7 ADAM21 ADAM33	1.21e-04	120	80	5	GO:0004222
GeneOntologyMolecularFunction	peptidase activity	ADAMTS10 ADAMTS4 PRSS53 ADAMTS7 ADAM21 PCSK7 TMPRSS2 ADAM33 CAPN15	1.20e-03	654	80	9	GO:0008233
GeneOntologyMolecularFunction	metallopeptidase activity	ADAMTS10 ADAMTS4 ADAMTS7 ADAM21 ADAM33	1.25e-03	200	80	5	GO:0008237
GeneOntologyBiologicalProcess	cell-cell adhesion	BOC ERBB2 CELSR3 TENM3 EGFR PRICKLE1 PKD1L1 PKD1 TNFRSF21 SVEP1 MEGF10 NOTCH4 CRB2 PEAR1 CFHR4	1.23e-05	1077	79	15	GO:0098609
GeneOntologyBiologicalProcess	cellular component maintenance	PRICKLE1 CNTNAP1 ZMYND8 CSMD2 SHROOM2	4.31e-05	101	79	5	GO:0043954
GeneOntologyBiologicalProcess	postsynaptic density organization	PRICKLE1 CNTNAP1 ZMYND8 CSMD2	7.23e-05	58	79	4	GO:0097106
GeneOntologyBiologicalProcess	cell junction maintenance	PRICKLE1 CNTNAP1 CSMD2 SHROOM2	1.13e-04	65	79	4	GO:0034331
GeneOntologyBiologicalProcess	regulation of complement activation	CR1L SVEP1 CFHR4	1.48e-04	27	79	3	GO:0030449
GeneOntologyBiologicalProcess	complement activation	CR1L SVEP1 CFHR4 CFHR3	1.51e-04	70	79	4	GO:0006956
GeneOntologyBiologicalProcess	postsynaptic specialization organization	PRICKLE1 CNTNAP1 ZMYND8 CSMD2	1.59e-04	71	79	4	GO:0099084
Domain	EGF_3	FBLN7 CELSR3 TENM3 ADAM21 CNTNAP1 ADAM33 SSPOP SVEP1 MEGF10 NOTCH4 CRB2 PEAR1 LRP8	1.52e-11	235	78	13	PS50026
Domain	EGF_1	FBLN7 CELSR3 TENM3 ADAM21 CNTNAP1 ADAM33 SSPOP SVEP1 MEGF10 NOTCH4 CRB2 PEAR1 LRP8	4.23e-11	255	78	13	PS00022
Domain	EGF_2	FBLN7 CELSR3 TENM3 ADAM21 CNTNAP1 ADAM33 SSPOP SVEP1 MEGF10 NOTCH4 CRB2 PEAR1 LRP8	6.83e-11	265	78	13	PS01186
Domain	EGF-like_dom	FBLN7 CELSR3 TENM3 ADAM21 CNTNAP1 ADAM33 SVEP1 MEGF10 NOTCH4 CRB2 PEAR1 LRP8	4.82e-10	249	78	12	IPR000742
Domain	EGF-like_CS	FBLN7 CELSR3 TENM3 ADAM21 CNTNAP1 ADAM33 SVEP1 MEGF10 NOTCH4 CRB2 PEAR1 LRP8	8.26e-10	261	78	12	IPR013032
Domain	Sushi	FBLN7 CSMD2 CR1L CSMD3 SVEP1 CFHR4 CFHR3	1.94e-09	52	78	7	PF00084
Domain	CCP	FBLN7 CSMD2 CR1L CSMD3 SVEP1 CFHR4 CFHR3	2.55e-09	54	78	7	SM00032
Domain	SUSHI	FBLN7 CSMD2 CR1L CSMD3 SVEP1 CFHR4 CFHR3	3.31e-09	56	78	7	PS50923
Domain	EGF	FBLN7 CELSR3 TENM3 CNTNAP1 ADAM33 SVEP1 MEGF10 NOTCH4 CRB2 PEAR1 LRP8	3.67e-09	235	78	11	SM00181
Domain	Sushi_SCR_CCP_dom	FBLN7 CSMD2 CR1L CSMD3 SVEP1 CFHR4 CFHR3	3.76e-09	57	78	7	IPR000436
Domain	TSP_1	ADAMTS10 CCN4 ADAMTS4 ADAMTS7 ADAMTSL3 SSPOP	2.45e-07	63	78	6	PF00090
Domain	TSP1	ADAMTS10 CCN4 ADAMTS4 ADAMTS7 ADAMTSL3 SSPOP	2.96e-07	65	78	6	SM00209
Domain	TSP1_rpt	ADAMTS10 CCN4 ADAMTS4 ADAMTS7 ADAMTSL3 SSPOP	2.96e-07	65	78	6	IPR000884
Domain	TSP1	ADAMTS10 CCN4 ADAMTS4 ADAMTS7 ADAMTSL3 SSPOP	2.96e-07	65	78	6	PS50092
Domain	Peptidase_M12B_N	ADAMTS10 ADAMTS4 ADAMTS7 ADAM21 ADAM33	5.75e-07	39	78	5	IPR002870
Domain	Pep_M12B_propep	ADAMTS10 ADAMTS4 ADAMTS7 ADAM21 ADAM33	5.75e-07	39	78	5	PF01562
Domain	DISINTEGRIN_1	ADAMTS10 ADAMTS4 ADAMTS7 ADAM21 ADAM33	6.55e-07	40	78	5	PS00427
Domain	Reprolysin	ADAMTS10 ADAMTS4 ADAMTS7 ADAM21 ADAM33	6.55e-07	40	78	5	PF01421
Domain	ADAM_MEPRO	ADAMTS10 ADAMTS4 ADAMTS7 ADAM21 ADAM33	6.55e-07	40	78	5	PS50215
Domain	DISINTEGRIN_2	ADAMTS10 ADAMTS4 ADAMTS7 ADAM21 ADAM33	6.55e-07	40	78	5	PS50214
Domain	Peptidase_M12B	ADAMTS10 ADAMTS4 ADAMTS7 ADAM21 ADAM33	6.55e-07	40	78	5	IPR001590
Domain	Disintegrin_dom	ADAMTS10 ADAMTS4 ADAMTS7 ADAM21 ADAM33	7.43e-07	41	78	5	IPR001762
Domain	EGF	FBLN7 CELSR3 CNTNAP1 SVEP1 NOTCH4 CRB2 LRP8	9.55e-07	126	78	7	PF00008
Domain	Peptidase_M12B_ADAM-TS	ADAMTS10 ADAMTS4 ADAMTS7 ADAMTSL3	2.81e-06	24	78	4	IPR013273
Domain	ASX_HYDROXYL	FBLN7 CELSR3 SVEP1 NOTCH4 CRB2 LRP8	3.81e-06	100	78	6	PS00010
Domain	hEGF	SVEP1 MEGF10 NOTCH4 CRB2	5.34e-06	28	78	4	PF12661
Domain	EGF-type_Asp/Asn_hydroxyl_site	FBLN7 CELSR3 SVEP1 NOTCH4 CRB2 LRP8	5.34e-06	106	78	6	IPR000152
Domain	EGF_CA	FBLN7 CELSR3 SVEP1 NOTCH4 CRB2 LRP8	1.20e-05	122	78	6	SM00179
Domain	EGF-like_Ca-bd_dom	FBLN7 CELSR3 SVEP1 NOTCH4 CRB2 LRP8	1.32e-05	124	78	6	IPR001881
Domain	MetalloPept_cat_dom	ADAMTS10 ADAMTS4 ADAMTS7 ADAM21 ADAM33	2.23e-05	81	78	5	IPR024079
Domain	-	ADAMTS10 ADAMTS4 ADAMTS7 ADAM21 ADAM33	2.23e-05	81	78	5	3.40.390.10
Domain	EMI	SSPOP MEGF10 PEAR1	4.57e-05	17	78	3	PS51041
Domain	LDLRA_1	PKD1 TMPRSS2 SSPOP LRP8	4.76e-05	48	78	4	PS01209
Domain	Growth_fac_rcpt_	CCN4 ERBB2 EGFR SVEP1 NOTCH4 LRP8	4.82e-05	156	78	6	IPR009030
Domain	LDLRA_2	PKD1 TMPRSS2 SSPOP LRP8	5.17e-05	49	78	4	PS50068
Domain	EGF_Ca-bd_CS	FBLN7 SVEP1 NOTCH4 CRB2 LRP8	5.33e-05	97	78	5	IPR018097
Domain	ZINC_PROTEASE	ADAMTS10 ADAMTS4 ADAMTS7 ADAM21 ADAM33	5.60e-05	98	78	5	PS00142
Domain	EGF_CA	FBLN7 SVEP1 NOTCH4 CRB2 LRP8	5.87e-05	99	78	5	PS01187
Domain	PLAC	ADAMTS10 ADAMTS7 ADAMTSL3	6.47e-05	19	78	3	PS50900
Domain	PLAC	ADAMTS10 ADAMTS7 ADAMTSL3	6.47e-05	19	78	3	IPR010909
Domain	REJ	PKD1L1 PKD1	1.03e-04	4	78	2	PS51111
Domain	Tyr_kinase_EGF/ERB/XmrK_rcpt	ERBB2 EGFR	1.03e-04	4	78	2	IPR016245
Domain	REJ_dom	PKD1L1 PKD1	1.03e-04	4	78	2	IPR014010
Domain	EGF_extracell	TENM3 ADAM33 SVEP1 MEGF10	1.15e-04	60	78	4	IPR013111
Domain	EGF_2	TENM3 ADAM33 SVEP1 MEGF10	1.15e-04	60	78	4	PF07974
Domain	ADAM_spacer1	ADAMTS10 ADAMTS4 ADAMTS7	1.17e-04	23	78	3	IPR010294
Domain	ADAM_spacer1	ADAMTS10 ADAMTS4 ADAMTS7	1.17e-04	23	78	3	PF05986
Domain	ACR	ADAMTS4 ADAM21 ADAM33	1.91e-04	27	78	3	SM00608
Domain	ADAM_Cys-rich	ADAMTS4 ADAM21 ADAM33	1.91e-04	27	78	3	IPR006586
Domain	PKD/REJ-like	PKD1L1 PKD1	2.55e-04	6	78	2	IPR002859
Domain	GF_recep_IV	ERBB2 EGFR	2.55e-04	6	78	2	PF14843
Domain	GF_recep_IV	ERBB2 EGFR	2.55e-04	6	78	2	IPR032778
Domain	REJ	PKD1L1 PKD1	2.55e-04	6	78	2	PF02010
Domain	Furin-like	ERBB2 EGFR	3.57e-04	7	78	2	PF00757
Domain	Rcpt_L-dom	ERBB2 EGFR	3.57e-04	7	78	2	IPR000494
Domain	PKD	PKD1L1 PKD1	3.57e-04	7	78	2	PF00801
Domain	Furin-like_Cys-rich_dom	ERBB2 EGFR	3.57e-04	7	78	2	IPR006211
Domain	Recep_L_domain	ERBB2 EGFR	3.57e-04	7	78	2	PF01030
Domain	-	ERBB2 EGFR	3.57e-04	7	78	2	3.80.20.20
Domain	Laminin_EGF	CELSR3 MEGF10 PEAR1	4.17e-04	35	78	3	PF00053
Domain	EGF_Lam	CELSR3 MEGF10 PEAR1	4.17e-04	35	78	3	SM00180
Domain	GPS	CELSR3 PKD1L1 PKD1	4.53e-04	36	78	3	PS50221
Domain	EGF_CA	FBLN7 SVEP1 NOTCH4 LRP8	4.61e-04	86	78	4	PF07645
Domain	GPS	CELSR3 PKD1L1 PKD1	4.92e-04	37	78	3	IPR000203
Domain	LAM_G_DOMAIN	CELSR3 CNTNAP1 CRB2	5.32e-04	38	78	3	PS50025
Domain	Laminin_EGF	CELSR3 MEGF10 PEAR1	5.32e-04	38	78	3	IPR002049
Domain	PKD/Chitinase_dom	PKD1L1 PKD1	6.08e-04	9	78	2	IPR022409
Domain	PKD	PKD1L1 PKD1	6.08e-04	9	78	2	SM00089
Domain	LDLR_class-A_CS	TMPRSS2 SSPOP LRP8	6.19e-04	40	78	3	IPR023415
Domain	Laminin_G_2	CELSR3 CNTNAP1 CRB2	6.19e-04	40	78	3	PF02210
Domain	CYSTEINE_SWITCH	ADAMTS7 ADAM21 ADAM33	6.66e-04	41	78	3	PS00546
Domain	-	CELSR3 CNTNAP1 SVEP1 CRB2	6.72e-04	95	78	4	2.60.120.200
Domain	Pept_M10_metallopeptidase	ADAMTS7 ADAM21 ADAM33	7.67e-04	43	78	3	IPR001818
Domain	LamG	CELSR3 CNTNAP1 CRB2	8.20e-04	44	78	3	SM00282
Domain	PKD	PKD1L1 PKD1	9.24e-04	11	78	2	PS50093
Domain	PKD_dom	PKD1L1 PKD1	9.24e-04	11	78	2	IPR000601
Domain	PKD_channel	PKD1L1 PKD1	9.24e-04	11	78	2	PF08016
Domain	PKD1_2_channel	PKD1L1 PKD1	9.24e-04	11	78	2	IPR013122
Domain	-	PKD1L1 PKD1	9.24e-04	11	78	2	2.60.40.670
Domain	-	TMPRSS2 SSPOP LRP8	9.35e-04	46	78	3	4.10.400.10
Domain	6-blade_b-propeller_TolB-like	TENM3 WDR6 LRP8	9.35e-04	46	78	3	IPR011042
Domain	LDrepeatLR_classA_rpt	TMPRSS2 SSPOP LRP8	1.12e-03	49	78	3	IPR002172
Domain	LDLa	TMPRSS2 SSPOP LRP8	1.12e-03	49	78	3	SM00192
Domain	PLAC	ADAMTS10 ADAMTSL3	1.52e-03	14	78	2	PF08686
Domain	Laminin_G	CELSR3 CNTNAP1 CRB2	1.83e-03	58	78	3	IPR001791
Domain	EMI_domain	MEGF10 PEAR1	1.99e-03	16	78	2	IPR011489
Domain	Disintegrin_CS	ADAM21 ADAM33	1.99e-03	16	78	2	IPR018358
Domain	LH2	PKD1L1 PKD1	2.52e-03	18	78	2	SM00308
Domain	Furin_repeat	ERBB2 EGFR	2.52e-03	18	78	2	IPR006212
Domain	CTCK_1	CCN4 SSPOP	2.52e-03	18	78	2	PS01185
Domain	ADAM_CR	ADAM21 ADAM33	2.52e-03	18	78	2	PF08516
Domain	FU	ERBB2 EGFR	2.52e-03	18	78	2	SM00261
Domain	-	ADAM21 ADAM33	3.12e-03	20	78	2	4.10.70.10
Domain	FA58C	CNTNAP1 SSPOP	3.43e-03	21	78	2	SM00231
Domain	PLAT	PKD1L1 PKD1	3.43e-03	21	78	2	PS50095
Domain	-	PKD1L1 PKD1	3.43e-03	21	78	2	2.60.60.20
Domain	Disintegrin	ADAM21 ADAM33	3.43e-03	21	78	2	PF00200
Domain	SRCR	SSC5D TMPRSS2	3.43e-03	21	78	2	PF00530
Domain	FA58C_3	CNTNAP1 SSPOP	3.43e-03	21	78	2	PS50022
Domain	PLAT	PKD1L1 PKD1	3.43e-03	21	78	2	PF01477
Pathway	REACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS	ADAMTS10 ADAMTS4 ADAMTS7 ADAMTSL3 SSPOP LFNG NOTCH4	6.55e-09	68	54	7	M27303
Pathway	REACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS	ADAMTS10 ADAMTS4 ADAMTS7 ADAMTSL3 SSPOP	3.56e-07	39	54	5	M27417
Pathway	REACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS	ADAMTS10 ADAMTS4 ADAMTS7 ADAMTSL3 SSPOP	3.56e-07	39	54	5	MM15165
Pathway	REACTOME_DISEASES_OF_GLYCOSYLATION	ADAMTS10 ADAMTS4 ADAMTS7 ADAMTSL3 SSPOP LFNG NOTCH4	1.13e-06	143	54	7	M27275
Pathway	REACTOME_DISEASES_OF_METABOLISM	ADAMTS10 ADAMTS4 ADAMTS7 ADAMTSL3 SSPOP LFNG NOTCH4	4.41e-05	250	54	7	M27554
Pathway	REACTOME_O_LINKED_GLYCOSYLATION	ADAMTS10 ADAMTS4 ADAMTS7 ADAMTSL3 SSPOP	5.90e-05	109	54	5	MM15164
Pathway	REACTOME_O_LINKED_GLYCOSYLATION	ADAMTS10 ADAMTS4 ADAMTS7 ADAMTSL3 SSPOP	6.43e-05	111	54	5	M27416
Pathway	REACTOME_DEFECTIVE_LFNG_CAUSES_SCDO3	LFNG NOTCH4	1.43e-04	5	54	2	M27411
Pathway	KEGG_MEDICUS_REFERENCE_REGULATION_OF_COMPLEMENT_CASCADE_CFHR	CFHR4 CFHR3	2.14e-04	6	54	2	M47880
Pathway	KEGG_MEDICUS_VARIANT_ERBB2_OVEREXPRESSION_TO_EGF_JAK_STAT_SIGNALING_PATHWAY	ERBB2 EGFR	2.99e-04	7	54	2	M47431
Pathway	WP_SOMITOGENESIS_IN_THE_CONTEXT_OF_SPONDYLOCOSTAL_DYSOSTOSIS	HES7 LFNG	5.10e-04	9	54	2	M39869
Pathway	WP_GENE_REGULATORY_NETWORK_MODELING_SOMITOGENESIS	HES7 LFNG	7.75e-04	11	54	2	M39647
Pathway	REACTOME_ERBB2_ACTIVATES_PTK6_SIGNALING	ERBB2 EGFR	7.75e-04	11	54	2	MM15478
Pathway	KEGG_MEDICUS_VARIANT_ERBB2_OVEREXPRESSION_TO_PI3K_SIGNALING_PATHWAY	ERBB2 EGFR	9.27e-04	12	54	2	M47393
Pathway	REACTOME_ERBB2_ACTIVATES_PTK6_SIGNALING	ERBB2 EGFR	1.09e-03	13	54	2	M27729
Pathway	REACTOME_ERBB2_REGULATES_CELL_MOTILITY	ERBB2 EGFR	1.09e-03	13	54	2	MM15320
Pathway	REACTOME_PI3K_EVENTS_IN_ERBB2_SIGNALING	ERBB2 EGFR	1.27e-03	14	54	2	MM14761
Pathway	REACTOME_SHC1_EVENTS_IN_ERBB2_SIGNALING	ERBB2 EGFR	1.27e-03	14	54	2	MM14531
Pathway	PID_ERBB_NETWORK_PATHWAY	ERBB2 EGFR	1.46e-03	15	54	2	M201
Pathway	REACTOME_ERBB2_REGULATES_CELL_MOTILITY	ERBB2 EGFR	1.46e-03	15	54	2	M27608
Pathway	REACTOME_TFAP2_AP_2_FAMILY_REGULATES_TRANSCRIPTION_OF_GROWTH_FACTORS_AND_THEIR_RECEPTORS	ERBB2 EGFR	1.46e-03	15	54	2	M27766
Pathway	REACTOME_GRB2_EVENTS_IN_ERBB2_SIGNALING	ERBB2 EGFR	1.67e-03	16	54	2	M562
Pathway	REACTOME_PI3K_EVENTS_IN_ERBB2_SIGNALING	ERBB2 EGFR	1.67e-03	16	54	2	M570
Pathway	REACTOME_SIGNALING_BY_ERBB2_ECD_MUTANTS	ERBB2 EGFR	1.67e-03	16	54	2	M29847
Pathway	KEGG_MEDICUS_REFERENCE_EGF_ERBB2_RAS_ERK_SIGNALING_PATHWAY	ERBB2 EGFR	1.67e-03	16	54	2	M47381
Pathway	KEGG_MEDICUS_VARIANT_NOTCH_OVEREXPRESSION_TO_NOTCH_SIGNALING_PATHWAY	ERBB2 NOTCH4	1.67e-03	16	54	2	M47424
Pubmed	O-fucosylation of thrombospondin type 1 repeats restricts epithelial to mesenchymal transition (EMT) and maintains epiblast pluripotency during mouse gastrulation.	ADAMTS10 CCN4 ADAMTS4 ADAMTS7 ADAMTSL3 SSPOP	2.92e-08	75	84	6	20637190
Pubmed	Hes7 3'UTR is required for somite segmentation function.	MYOG HES7 LFNG	5.43e-08	4	84	3	25248974
Pubmed	ADAMTS: a novel family of extracellular matrix proteases.	ADAMTS10 ADAMTS4 ADAMTS7	1.61e-06	10	84	3	11167130
Pubmed	Expression of Notch signaling pathway genes in mouse embryos lacking beta4galactosyltransferase-1.	MYOG HES7 LFNG	2.94e-06	12	84	3	16412699
Pubmed	Insights on ADAMTS proteases and ADAMTS-like proteins from mammalian genetics.	ADAMTS10 ADAMTS4 ADAMTS7	2.94e-06	12	84	3	25770910
Pubmed	Disruption of somitogenesis by a novel dominant allele of Lfng suggests important roles for protein processing and secretion.	MYOG HES7 LFNG	3.82e-06	13	84	3	26811377
Pubmed	Defining a link with autosomal-dominant polycystic kidney disease in mice with congenitally low expression of Pkd1.	ERBB2 EGFR PKD1	4.85e-06	14	84	3	16400024
Pubmed	Prognostic and predictive values of EGFR overexpression and EGFR copy number alteration in HER2-positive breast cancer.	ERBB2 EGFR	5.76e-06	2	84	2	25349977
Pubmed	Prognostic role of human epidermal growth factor receptor in gastric cancer: a systematic review and meta-analysis.	ERBB2 EGFR	5.76e-06	2	84	2	23871709
Pubmed	ADAMTS7B, the full-length product of the ADAMTS7 gene, is a chondroitin sulfate proteoglycan containing a mucin domain.	ADAMTS4 ADAMTS7	5.76e-06	2	84	2	15192113
Pubmed	HER1 R497K and HER2 I655V polymorphisms are linked to development of breast cancer.	ERBB2 EGFR	5.76e-06	2	84	2	23594562
Pubmed	Identification of autophosphorylation sites of HER2/neu.	ERBB2 EGFR	5.76e-06	2	84	2	1706616
Pubmed	Effects of the combined blockade of EGFR and ErbB-2 on signal transduction and regulation of cell cycle regulatory proteins in breast cancer cells.	ERBB2 EGFR	5.76e-06	2	84	2	19946741
Pubmed	EGFR and ERBB2 Exon 20 Insertion Mutations in Chinese Non-small Cell Lung Cancer Patients: Pathological and Molecular Characterization, and First-Line Systemic Treatment Evaluation.	ERBB2 EGFR	5.76e-06	2	84	2	38416376
Pubmed	Evolutionary analysis of the ErbB receptor and ligand families.	ERBB2 EGFR	5.76e-06	2	84	2	10824084
Pubmed	Genetic and expression analysis of HER-2 and EGFR genes in salivary duct carcinoma: empirical and therapeutic significance.	ERBB2 EGFR	5.76e-06	2	84	2	20371674
Pubmed	Epidermal growth factor receptor status in breast cancer metastases to the central nervous system. Comparison with HER-2/neu status.	ERBB2 EGFR	5.76e-06	2	84	2	15335267
Pubmed	Significance of epidermal growth factor receptor expression in breast cancer.	ERBB2 EGFR	5.76e-06	2	84	2	21104342
Pubmed	Synergistic Blockade of EGFR and HER2 by New-Generation EGFR Tyrosine Kinase Inhibitor Enhances Radiation Effect in Bladder Cancer Cells.	ERBB2 EGFR	5.76e-06	2	84	2	25589492
Pubmed	Protein overexpression and gene amplification of HER-2 and EGFR in colorectal cancers: an immunohistochemical and fluorescent in situ hybridization study.	ERBB2 EGFR	5.76e-06	2	84	2	15143334
Pubmed	An EGFR/HER2-Bispecific and enediyne-energized fusion protein shows high efficacy against esophageal cancer.	ERBB2 EGFR	5.76e-06	2	84	2	24664246
Pubmed	Impact of common epidermal growth factor receptor and HER2 variants on receptor activity and inhibition by lapatinib.	ERBB2 EGFR	5.76e-06	2	84	2	18199554
Pubmed	Status of HER1 and HER2 in peritoneal, ovarian and colorectal endometriosis and ovarian endometrioid adenocarcinoma.	ERBB2 EGFR	5.76e-06	2	84	2	19294416
Pubmed	Interferon Regulatory Factor-5 in Resident Macrophage Promotes Polycystic Kidney Disease.	PKD1 IRF5	5.76e-06	2	84	2	33490963
Pubmed	Expression of erbB-1 and erbB-2 genes in normal and pathological human endometrium.	ERBB2 EGFR	5.76e-06	2	84	2	17549377
Pubmed	Prognostic implications of EGFR and HER-2 alteration assessed by immunohistochemistry and silver in situ hybridization in gastric cancer patients following curative resection.	ERBB2 EGFR	5.76e-06	2	84	2	23955257
Pubmed	The efficient elimination of solid tumor cells by EGFR-specific and HER2-specific scFv-SNAP fusion proteins conjugated to benzylguanine-modified auristatin F.	ERBB2 EGFR	5.76e-06	2	84	2	27502168
Pubmed	Frequent genetic alterations in EGFR- and HER2-driven pathways in breast cancer brain metastases.	ERBB2 EGFR	5.76e-06	2	84	2	23665199
Pubmed	Epidermal growth factor receptor activity is necessary for mouse basal cell proliferation.	ERBB2 EGFR	5.76e-06	2	84	2	25217659
Pubmed	EGFR and HER2 expression in advanced biliary tract cancer.	ERBB2 EGFR	5.76e-06	2	84	2	19777609
Pubmed	Differential cytoskeletal association of ErbB1 and ErbB2 during keratinocyte differentiation.	ERBB2 EGFR	5.76e-06	2	84	2	12135609
Pubmed	Dual inhibition of ErbB1 and ErbB2 in cancer by recombinant human prolidase mutant hPEPD-G278D.	ERBB2 EGFR	5.76e-06	2	84	2	27286447
Pubmed	Increased concentrations of growth factors and activation of the EGFR system in breast cancer.	ERBB2 EGFR	5.76e-06	2	84	2	23089711
Pubmed	EGFR Expression in HER2-Driven Breast Cancer Cells.	ERBB2 EGFR	5.76e-06	2	84	2	33260837
Pubmed	Membrane-bound trafficking regulates nuclear transport of integral epidermal growth factor receptor (EGFR) and ErbB-2.	ERBB2 EGFR	5.76e-06	2	84	2	22451678
Pubmed	The immune microenvironment in EGFR- and ERBB2-mutated lung adenocarcinoma.	ERBB2 EGFR	5.76e-06	2	84	2	34487971
Pubmed	Screening and validation of dinucleotide repeats in intron 1 of the human EGFR gene and its paralog in the HER2 gene.	ERBB2 EGFR	5.76e-06	2	84	2	18946768
Pubmed	Dissecting the molecular recognition of dual lapatinib derivatives for EGFR/HER2.	ERBB2 EGFR	5.76e-06	2	84	2	31828486
Pubmed	Design, biological evaluation and 3D QSAR studies of novel dioxin-containing pyrazoline derivatives with thiourea skeleton as selective HER-2 inhibitors.	ERBB2 EGFR	5.76e-06	2	84	2	27273260
Pubmed	Association of EGFR and HER2 polymorphisms with risk and clinical features of thyroid cancer.	ERBB2 EGFR	5.76e-06	2	84	2	19860576
Pubmed	Androgen receptor controls EGFR and ERBB2 gene expression at different levels in prostate cancer cell lines.	ERBB2 EGFR	5.76e-06	2	84	2	19318561
Pubmed	Induction of cancer cell migration by epidermal growth factor is initiated by specific phosphorylation of tyrosine 1248 of c-erbB-2 receptor via EGFR.	ERBB2 EGFR	5.76e-06	2	84	2	12354693
Pubmed	Fluorescence-Raman dual modal endoscopic system for multiplexed molecular diagnostics.	ERBB2 EGFR	5.76e-06	2	84	2	25820115
Pubmed	HER2 induced EMT and tumorigenicity in breast epithelial progenitor cells is inhibited by coexpression of EGFR.	ERBB2 EGFR	5.76e-06	2	84	2	26686087
Pubmed	Expression of EGFR, Her2 predict lymph node metastasis (LNM)-associated metastasis in colorectal cancer.	ERBB2 EGFR	5.76e-06	2	84	2	23220854
Pubmed	Amplification and expression of EGFR and ERBB2 in Wilms tumor.	ERBB2 EGFR	5.76e-06	2	84	2	19781441
Pubmed	Cardiac ErbB-1/ErbB-2 mutant expression in young adult mice leads to cardiac dysfunction.	ERBB2 EGFR	5.76e-06	2	84	2	18599591
Pubmed	Therapeutic potential of the dual EGFR/HER2 inhibitor AZD8931 in circumventing endocrine resistance.	ERBB2 EGFR	5.76e-06	2	84	2	24554387
Pubmed	Targeting EGFR and HER-2 with cetuximab- and trastuzumab-mediated immunotherapy in oesophageal squamous cell carcinoma.	ERBB2 EGFR	5.76e-06	2	84	2	17622245
Pubmed	Epidermal growth factor receptor, c-erbB2 and c-erbB3 receptor interaction, and related cell cycle kinetics of SK-BR-3 and BT474 breast carcinoma cells.	ERBB2 EGFR	5.76e-06	2	84	2	11500850
Pubmed	Gangliosides influence EGFR/ErbB2 heterodimer stability but they do not modify EGF-dependent ErbB2 phosphorylation.	ERBB2 EGFR	5.76e-06	2	84	2	20156584
Pubmed	EGFR and HER-2 oncogenes expression in an experimental model of two-stage chemically induced carcinogenesis in mouse skin.	ERBB2 EGFR	5.76e-06	2	84	2	38443188
Pubmed	Differential spatial expression and activation pattern of EGFR and HER2 in human breast cancer.	ERBB2 EGFR	5.76e-06	2	84	2	17611648
Pubmed	The correlation between cytoplasmic overexpression of epidermal growth factor receptor and tumor aggressiveness: poor prognosis in patients with pancreatic ductal adenocarcinoma.	ERBB2 EGFR	5.76e-06	2	84	2	15211117
Pubmed	A novel dual EGFR/HER2 inhibitor KU004 induces cell cycle arrest and apoptosis in HER2-overexpressing cancer cells.	ERBB2 EGFR	5.76e-06	2	84	2	26437915
Pubmed	EGFR and HER2 receptor kinase signaling mediate epithelial cell invasion by Candida albicans during oropharyngeal infection.	ERBB2 EGFR	5.76e-06	2	84	2	22891338
Pubmed	Expression of epidermal growth factor receptor and HER-2 in pediatric embryonal brain tumors.	ERBB2 EGFR	5.76e-06	2	84	2	20962551
Pubmed	Structural and energetic basis for the molecular recognition of dual synthetic vs. natural inhibitors of EGFR/HER2.	ERBB2 EGFR	5.76e-06	2	84	2	29329808
Pubmed	Role of epidermal growth factor and ErbB2 receptors in 3T3-L1 adipogenesis.	ERBB2 EGFR	5.76e-06	2	84	2	17372305
Pubmed	Prognostic significance of the co-expression of EGFR and HER2 in adenocarcinoma of the uterine cervix.	ERBB2 EGFR	5.76e-06	2	84	2	28859123
Pubmed	Trastuzumab plus chemotherapy in gastric cancer overexpressing HER-2 and EGFR: a case report.	ERBB2 EGFR	5.76e-06	2	84	2	21346384
Pubmed	Activation of EGFR and ERBB2 by Helicobacter pylori results in survival of gastric epithelial cells with DNA damage.	ERBB2 EGFR	5.76e-06	2	84	2	24530706
Pubmed	Molecular dynamics simulations of asymmetric heterodimers of HER1/HER2 complexes.	ERBB2 EGFR	5.76e-06	2	84	2	29280017
Pubmed	A novel proteotoxic combination therapy for EGFR+ and HER2+ cancers.	ERBB2 EGFR	5.76e-06	2	84	2	30718919
Pubmed	Immunohistochemical correlation of epidermal growth factor receptor and c-erbB-2 with histopathologic grading of mucoepidermoid carcinoma.	ERBB2 EGFR	5.76e-06	2	84	2	23361279
Pubmed	Dual-Receptor-Targeted (DRT) Radiation Nanomedicine Labeled with 177Lu Is More Potent for Killing Human Breast Cancer Cells That Coexpress HER2 and EGFR Than Single-Receptor-Targeted (SRT) Radiation Nanomedicines.	ERBB2 EGFR	5.76e-06	2	84	2	32022567
Pubmed	Comparative analysis of fluorescence resonance energy transfer (FRET) and proximity ligation assay (PLA).	ERBB2 EGFR	5.76e-06	2	84	2	21480528
Pubmed	Targeting EGFR/HER2 pathways enhances the antiproliferative effect of gemcitabine in biliary tract and gallbladder carcinomas.	ERBB2 EGFR	5.76e-06	2	84	2	21087480
Pubmed	A Comparison of Immunohistochemical Expression of Epidermal Growth Factor Receptor and Human Epidermal Growth Factor Receptor 2 in Dental Follicles with Different Radiographic Sizes.	ERBB2 EGFR	5.76e-06	2	84	2	39205824
Pubmed	ErbB receptor-driven prolactinomas respond to targeted lapatinib treatment in female transgenic mice.	ERBB2 EGFR	5.76e-06	2	84	2	25375038
Pubmed	Lapatinib, a dual inhibitor of ErbB-1/-2 receptors, enhances effects of combination chemotherapy in bladder cancer cells.	ERBB2 EGFR	5.76e-06	2	84	2	19287975
Pubmed	The signaling and transformation potency of the overexpressed HER2 protein is dependent on the normally-expressed EGFR.	ERBB2 EGFR	5.76e-06	2	84	2	21911055
Pubmed	Pre-diagnostic serum levels of EGFR and ErbB2 and genetic glioma risk variants: a nested case-control study.	ERBB2 EGFR	5.76e-06	2	84	2	26906551
Pubmed	Cross-reactivity of EGFR mutation-specific immunohistochemistry assay in HER2-positive tumors.	ERBB2 EGFR	5.76e-06	2	84	2	25390349
Pubmed	Differential c-erbB-1 and c-erbB-2 mRNA expression in cancer of the pancreas compared with cancer of the papilla of Vater.	ERBB2 EGFR	5.76e-06	2	84	2	16489645
Pubmed	Elevated levels of epidermal growth factor receptor/c-erbB2 heterodimers mediate an autocrine growth regulatory pathway in tamoxifen-resistant MCF-7 cells.	ERBB2 EGFR	5.76e-06	2	84	2	12586780
Pubmed	Overexpression of Epidermal Growth Factor Receptor (EGFR) and HER-2 in Bladder Carcinoma and Its Association with Patients' Clinical Features.	ERBB2 EGFR	5.76e-06	2	84	2	30296252
Pubmed	EGFR and ERBB2 Germline Mutations in Chinese Lung Cancer Patients and Their Roles in Genetic Susceptibility to Cancer.	ERBB2 EGFR	5.76e-06	2	84	2	30610926
Pubmed	Multiple ErbB-2/Neu Phosphorylation Sites Mediate Transformation through Distinct Effector Proteins.	ERBB2 EGFR	5.76e-06	2	84	2	11500516
Pubmed	EGFR negates the proliferative effect of oncogenic HER2 in MDA-MB-231 cells.	ERBB2 EGFR	5.76e-06	2	84	2	25935365
Pubmed	Flow cytometric in situ proximity ligation analyses of protein interactions and post-translational modification of the epidermal growth factor receptor family.	ERBB2 EGFR	5.76e-06	2	84	2	19650109
Pubmed	[Relationship between HER2/neu gene amplification and protein expression and prognosis in patients with advanced gastric carcinoma].	ERBB2 EGFR	5.76e-06	2	84	2	20038314
Pubmed	The Dipole Potential Modifies the Clustering and Ligand Binding Affinity of ErbB Proteins and Their Signaling Efficiency.	ERBB2 EGFR	5.76e-06	2	84	2	27775011
Pubmed	Antitumor and antiangiogenic effect of the dual EGFR and HER-2 tyrosine kinase inhibitor lapatinib in a lung cancer model.	ERBB2 EGFR	5.76e-06	2	84	2	20459769
Pubmed	Serum levels of epidermal growth factor and HER-2 neu in non small-cell lung cancer: prognostic correlation.	ERBB2 EGFR	5.76e-06	2	84	2	19093231
Pubmed	Circular HER2 RNA positive triple negative breast cancer is sensitive to Pertuzumab.	ERBB2 EGFR	5.76e-06	2	84	2	32917240
Pubmed	Fibulin7 Mediated Pathological Cardiac Remodeling through EGFR Binding and EGFR-Dependent FAK/AKT Signaling Activation.	FBLN7 EGFR	5.76e-06	2	84	2	37344348
Pubmed	EGFR and erbB2 in malignant peripheral nerve sheath tumors and implications for targeted therapy.	ERBB2 EGFR	5.76e-06	2	84	2	18650488
Pubmed	Genomic activation of the EGFR and HER2-neu genes in a significant proportion of invasive epithelial ovarian cancers.	ERBB2 EGFR	5.76e-06	2	84	2	18182111
Pubmed	Expression of herstatin, an autoinhibitor of HER-2/neu, inhibits transactivation of HER-3 by HER-2 and blocks EGF activation of the EGF receptor.	ERBB2 EGFR	5.76e-06	2	84	2	11526509
Pubmed	A role of Rab7 in stabilizing EGFR-Her2 and in sustaining Akt survival signal.	ERBB2 EGFR	5.76e-06	2	84	2	21928319
Pubmed	Correlations of EGFR mutations and increases in EGFR and HER2 copy number to gefitinib response in a retrospective analysis of lung cancer patients.	ERBB2 EGFR	5.76e-06	2	84	2	17626639
Pubmed	Affinity-Tuned ErbB2 or EGFR Chimeric Antigen Receptor T Cells Exhibit an Increased Therapeutic Index against Tumors in Mice.	ERBB2 EGFR	5.76e-06	2	84	2	26330166
Pubmed	EGFR and HER2 signals play a salvage role in MEK1-mutated gastric cancer after MEK inhibition.	ERBB2 EGFR	5.76e-06	2	84	2	26081723
Pubmed	Overexpression of c-erbB-2 oncoprotein and associated pathobiological factors in invasive primary breast cancer.	ERBB2 EGFR	5.76e-06	2	84	2	15233293
Pubmed	Critical roles for EGFR and EGFR-HER2 clusters in EGF binding of SW620 human carcinoma cells.	ERBB2 EGFR	5.76e-06	2	84	2	35612280
Pubmed	The Transmodulation of HER2 and EGFR by Substance P in Breast Cancer Cells Requires c-Src and Metalloproteinase Activation.	ERBB2 EGFR	5.76e-06	2	84	2	26114632
Pubmed	Capsaicin causes cell-cycle arrest and apoptosis in ER-positive and -negative breast cancer cells by modulating the EGFR/HER-2 pathway.	ERBB2 EGFR	5.76e-06	2	84	2	19855437
Pubmed	Assessment of HER1 (rs11543848) and HER2 (rs1136201) polymorphism and their association with colorectal cancer susceptibility in Khyber Pakhtunkhwa, Pakistan.	ERBB2 EGFR	5.76e-06	2	84	2	38040921
Pubmed	HER2 and EGFR amplification and expression in urothelial carcinoma occurs in distinct biological and molecular contexts.	ERBB2 EGFR	5.76e-06	2	84	2	28388586
Cytoband	17p13.1	HES7 SLC35G6 KDM6B SPEM1	6.83e-05	118	84	4	17p13.1
Cytoband	8q24.22	CCN4 PHF20L1	4.42e-04	17	84	2	8q24.22
GeneFamily	Hyalectan proteoglycans\|V-set domain containing\|Sushi domain containing\|C-type lectin domain containing	FBLN7 CSMD2 CR1L CSMD3 SVEP1 CFHR4 CFHR3	6.35e-10	57	59	7	1179
GeneFamily	ADAM metallopeptidases with thrombospondin type 1 motif	ADAMTS10 ADAMTS4 ADAMTS7	3.08e-05	19	59	3	50
GeneFamily	Erb-b2 receptor tyrosine kinases	ERBB2 EGFR	6.26e-05	4	59	2	1096
GeneFamily	Complement system\|Sushi domain containing	CR1L CFHR4 CFHR3	2.18e-04	36	59	3	492
GeneFamily	C2-set domain containing\|Immunoglobulin like domain containing\|Scavenger receptors	SSC5D MEGF10	3.49e-03	27	59	2	1253
GeneFamily	ADAM metallopeptidase domain containing\|CD molecules	ADAM21 ADAM33	3.49e-03	27	59	2	47
GeneFamily	CD molecules\|Tumor necrosis factor receptor superfamily\|Death inducing signaling complex	RELT TNFRSF21	4.02e-03	29	59	2	782
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HRGL2B	BOC EGFR KLF9 CSMD2 CABIN1 CSMD3 LFNG INKA2 CRB2	1.16e-05	439	84	9	M39054
ToppCell	5'-Adult-LymphNode-Mesenchymal-fibroblastic-Transitional_Stromal_3_(C3+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	BOC TENM3 ADAMTS4 EGFR KDM6B ADAMTSL3 SVEP1 CFHR3	1.97e-09	181	84	8	ab66a89f316b935d9ba1277426d976b1e9e39757
ToppCell	356C-Myeloid-Macrophage-FABP4+_Macrophage_3\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	BOC ADAMTS4 EGFR NOTUM PRICKLE1 ADAM33 SVEP1	4.54e-08	177	84	7	3d955ea938a1d2fb1b6d68d4997fd454bd632dfc
ToppCell	Fetal_29-31_weeks-Mesenchymal-chondrocyte-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	BOC C1QTNF8 FBLN7 TENM3 NOTUM EXTL1 ADAMTSL3	6.15e-08	185	84	7	8ed10ba581849c9c4ac4397226be2b62b4b3b900
ToppCell	Fetal_29-31_weeks-Mesenchymal-chondrocyte\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	BOC C1QTNF8 FBLN7 TENM3 NOTUM EXTL1 ADAMTSL3	6.15e-08	185	84	7	b8052cebb73f41abe6faf0aa847be7c8ef23ae94
ToppCell	5'-Adult-Distal_Rectal-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	BOC SSC5D ADAMTS4 EGFR ADAM33 SHROOM2 SVEP1	7.12e-08	189	84	7	f7d57723b8fb0f1e1485f51e3eff93ec0f39761e
ToppCell	Bronchial-10x5prime-Stromal-Fibroblastic-Fibro_myofibroblast\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	BOC CCN4 SSC5D ADAM33 GRIP2 SVEP1 GASK1A	1.01e-07	199	84	7	21335475bbfbad8a6943b8076a6c1c67f3eec5d3
ToppCell	Bronchus_Control_(B.)-Stromal-TX-Fibroblasts-4\|Bronchus_Control_(B.) / Sample group, Lineage and Cell type	BOC CCN4 SSC5D NOTUM APCDD1L ADAM33 GASK1A	1.05e-07	200	84	7	54b18c92daaa3b3368c0c46134b0c27e10c8dbb0
ToppCell	droplet-Trachea-nan-3m-Mesenchymal-mesenchymal_cell\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1E FBLN7 NOTUM KLF9 ADAMTSL3 CSMD3	1.45e-07	126	84	6	c3261ea8726400de87f1c8a5a5134ba2b2884f66
ToppCell	E18.5-samps-Mesenchymal-Pericyte-pericyte_C\|E18.5-samps / Age Group, Lineage, Cell class and subclass	ADAM21 ADAM33 GRIP2 ADAMTSL3 TNFRSF21 PEAR1	4.24e-07	151	84	6	3f2abaa42876ce7a71d934ff16abe0cab0991a05
ToppCell	facs-Brain_Non-Myeloid-Hippocampus_-18m-Macroglial-astrocyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SSC5D TENM3 MYOG R3HDML LFNG SPEM1	4.76e-07	154	84	6	5ed64bbf603290e6dc34f81d145982690b89dd0d
ToppCell	wk_20-22-Mesenchymal-Chondrocyte\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	BOC C1QTNF8 TENM3 NOTUM EXTL1 GASK1A	8.78e-07	171	84	6	d2938639e9a7c349e5a6ec61724222f9d127c89f
ToppCell	356C-Myeloid-Macrophage-FABP4+_Macrophage_3\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	BOC ADAMTS4 NOTUM PRICKLE1 ADAM33 SVEP1	1.04e-06	176	84	6	bfa1633e1b7a8a2f04d37fa07284fe9bc0199f46
ToppCell	TCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-6\|TCGA-Ovary / Sample_Type by Project: Shred V9	ADAMTS10 CCN4 SSC5D ADAMTS4 SVEP1 MEGF10	1.11e-06	178	84	6	142879e9393e721f9b05a6bb46995c9d6d713c95
ToppCell	facs-Bladder-nan-24m-Epithelial-bladder_mesenchymal_cell_(Car3+)\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTS4 NOTUM PRICKLE1 KLF9 KDM6B SVEP1	1.18e-06	180	84	6	12537d8a569faa69f474284d2c201475722b8ca1
ToppCell	TCGA-Bladder-Primary_Tumor-Urothelial_Carcinoma-Non-Papillary_Muscle_Invasive_Urothelial_Carcinoma-4\|TCGA-Bladder / Sample_Type by Project: Shred V9	ADAMTS10 BOC SSC5D CNTNAP1 TMPRSS2 ADAM33	1.39e-06	185	84	6	e1f3f0e974eb3fe1c05018beb9e124c7fb0cbe50
ToppCell	Adult-Mesenchymal-matrix_fibroblast_2_cell-D231\|Adult / Lineage, Cell type, age group and donor	ADAMTS10 BOC SSC5D ADAM33 ADAMTSL3 SVEP1	1.39e-06	185	84	6	fb6bd7e849ecf4ed9cd9c4e2a946a2d12d62f804
ToppCell	Control-Fibroblasts-Adventitial_FB\|Control / group, cell type (main and fine annotations)	BOC KLF9 ADAM33 ADAMTSL3 SVEP1 GASK1A	1.52e-06	188	84	6	706a26c372add839d947749f0521a0e1f5c9b0ec
ToppCell	Mesenchymal-chondrocyte\|World / Lineage, Cell type, age group and donor	BOC FBLN7 TENM3 NOTUM EXTL1 ADAMTSL3	1.52e-06	188	84	6	7b1e3f8a941eaa68e89c562129a92314642eec66
ToppCell	Adult-Mesenchymal-matrix_fibroblast_2_cell\|Adult / Lineage, Cell type, age group and donor	ADAMTS10 BOC ADAM33 ADAMTSL3 SVEP1 GASK1A	1.72e-06	192	84	6	d21f0f577156f17c899b08871046a26b88aea011
ToppCell	Parenchymal-NucSeq-Stromal-Chondrocytic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SIGLEC12 BOC LINC01600 EXTL1 CSMD3 CFHR3	1.77e-06	193	84	6	df4afb4848eb9d7d8d39e5c612919663cbbb2514
ToppCell	Parenchymal-NucSeq-Stromal-Chondrocytic-Chondrocyte\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SIGLEC12 BOC LINC01600 EXTL1 CSMD3 CFHR3	1.77e-06	193	84	6	ab36d684bde8fe77d11a5188425135328052c58b
ToppCell	facs-Bladder-nan-18m-Epithelial-bladder_mesenchymal_cell_(Car3+)\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CCN4 ADAMTS4 NOTUM KLF9 KDM6B SVEP1	1.83e-06	194	84	6	f4c9fc53ae31d58096906d9305b0b4082512a7e9
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	BOC CCN4 PRICKLE1 ADAM33 ADAMTSL3 SVEP1	1.83e-06	194	84	6	c49f72441b3557e2c3a9c4239e68c0cf0652814b
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	BOC CCN4 PRICKLE1 ADAM33 ADAMTSL3 SVEP1	1.88e-06	195	84	6	3c3703f092b6fc1b7333426fb5e2823bfb74bb57
ToppCell	droplet-Limb_Muscle-nan-18m-Mesenchymal-chondrocyte-like\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BOC CCN4 SSC5D FBLN7 EGFR SVEP1	1.94e-06	196	84	6	fcb275746bf51269ed8ba4cf93edb054a45f1ccd
ToppCell	5'-Adult-Appendix-Mesenchymal-fibroblastic\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	BOC ADAMTS4 EGFR ADAM33 KDM6B SVEP1	2.00e-06	197	84	6	ab5d3ebc73bd7cfc64381d14b92878b370205186
ToppCell	distal-mesenchymal-Adventitial_Fibroblast-2\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	BOC SSC5D TENM3 ADAM33 SVEP1 CFHR3	2.06e-06	198	84	6	bfd720e2dae3b6b3dc2bf8b2096c554fd456e756
ToppCell	Tracheal-NucSeq-Stromal-Peri/Epineurial_\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PRICKLE1 ADAM33 ADAMTSL3 CSMD3 SVEP1 PEAR1	2.12e-06	199	84	6	3835452e4848d7f7dd8651c17b746b271ef39688
ToppCell	Bronchus_Control_(B.)-Stromal-TX-Mesothelial-2\|Bronchus_Control_(B.) / Sample group, Lineage and Cell type	CCN4 ADAMTS7 EXTL1 SVEP1 SPEM1 GASK1A	2.12e-06	199	84	6	60a653100aff31f7f96796ff2ec634798bfb4b0d
ToppCell	distal-2-mesenchymal-Adventitial_Fibroblast\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	BOC SSC5D TENM3 ADAM33 SVEP1 CFHR3	2.12e-06	199	84	6	97b475f9110ef7bb29d9cf2109b7e43177830f05
ToppCell	Bronchial-NucSeq-Stromal-Fibroblastic-Fibro_perichondrial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	BOC C1QTNF8 TENM3 KLF9 ADAMTSL3 SVEP1	2.12e-06	199	84	6	abd6117f8a3d7e798d8471c16d97b34aaf50fc9c
ToppCell	Parenchymal-10x5prime-Stromal-Fibroblastic-Fibro_myofibroblast\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	BOC CCN4 SSC5D TENM3 SVEP1 GASK1A	2.18e-06	200	84	6	54806080b5e97859ee6a4a9b4f19e22021c218f5
ToppCell	Parenchymal-NucSeq-Stromal-Fibroblastic-Fibro_adventitial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	BOC ADAMTS4 KLF9 ADAM33 ADAMTSL3 SVEP1	2.18e-06	200	84	6	74e74123ea7bf38d337a3a0248a6a51437c6ab42
ToppCell	343B-Epithelial_cells-Epithelial-E_(AT2)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	HOXB2 SSC5D ADAM33 ADAMTSL3 GASK1A	1.06e-05	153	84	5	d5f5399ebbbff508c96ce7f01272716b61597ab5
ToppCell	343B-Epithelial_cells-Epithelial-E_(AT2)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	HOXB2 SSC5D ADAM33 ADAMTSL3 GASK1A	1.06e-05	153	84	5	32cf4ca828d228f23366480305592f9813fed7ff
ToppCell	Adult-Endothelial-endothelial_cell_of_artery-D122\|Adult / Lineage, Cell type, age group and donor	C1QTNF8 GRIP2 CCDC188 NOTCH4 PEAR1	1.66e-05	168	84	5	8c3e1e45b422813bcdfa4273b1167db649a312f5
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-proliferative_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CCN4 TENM3 LINC00304 SVEP1 PEAR1	1.71e-05	169	84	5	a84490724a206c9bbb145f7ce08613f91d100ac4
ToppCell	P15-Mesenchymal-mesenchymal_fibroblast-mesenchymal_progenitor_cell\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	FBLN7 ADAMTS7 ZNF575 SVEP1 MEGF10	1.76e-05	170	84	5	ba4ba66b624089ed50a9083176386c7941b4c7a3
ToppCell	wk_08-11-Mesenchymal-Chondrocyte-intermediate_chondrocyte\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	BOC TENM3 NOTUM EXTL1 LRP8	1.86e-05	172	84	5	415d57aa6278b8c12e7a2cf9c3fa5283389fb9b0
ToppCell	E16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_G2M\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CCN4 HOXB2 ADAMTSL3 CSMD3 TNFRSF21	2.02e-05	175	84	5	fa16c6ba08dc0cc22e8cf049db0577811d080df6
ToppCell	wk_15-18-Mesenchymal-Chondrocyte-intermediate_chondrocyte\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	BOC C1QTNF8 TENM3 PRICKLE1 MEGF10	2.02e-05	175	84	5	a84965d28438a4228d841b357c2cd75cf4b59a63
ToppCell	droplet-Pancreas-Exocrine-24m-Epithelial-pancreatic_ductal_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ERBB2 PLEKHS1 ADAM33 C11orf16 GASK1A	2.02e-05	175	84	5	6bb8fc2959583644f16b22e906af91af62a3a633
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CCN4 IL17REL ADAM33 ADAMTSL3 SVEP1	2.02e-05	175	84	5	795a6564d5a75ffd35d39f5274b9e8d28708bbc8
ToppCell	droplet-Pancreas-Exocrine-24m-Epithelial-pancreatic_ductal_cel\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ERBB2 PLEKHS1 ADAM33 C11orf16 GASK1A	2.02e-05	175	84	5	8902c38067f025b094ca9c28c449c32a66eded1c
ToppCell	droplet-Lung-nan-3m-Mesenchymal-pericyte_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CCN4 HOXB2 ADAMTSL3 SSPOP INKA2	2.14e-05	177	84	5	65709bd546cb1ec6aa2ddd8b2adb46e174eb9a9a
ToppCell	3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ADAMTS4 CNTNAP1 ADAMTSL3 INKA2 PEAR1	2.14e-05	177	84	5	452ec2df36c6d656a7cdadc55be545ccdb146a29
ToppCell	droplet-Lung-nan-3m-Mesenchymal-Pericyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CCN4 HOXB2 ADAMTSL3 SSPOP INKA2	2.14e-05	177	84	5	8684d47a547e2a06496f15e8da0200ecddc431e0
ToppCell	TCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Mucinous_Colon_Adenocarcinoma-10\|TCGA-Colorectal / Sample_Type by Project: Shred V9	FBLN7 TENM3 CSMD2 SVEP1 NOTCH4	2.26e-05	179	84	5	cc079ba015326dccde955c5eafa3e4a2e40de192
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_GGT8P\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	EGFR ESPNL GRIP2 ADAMTSL3 SSPOP	2.38e-05	181	84	5	9842537f9a607d8557c43790008d175edab1f32c
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CCN4 TENM3 ADAM33 ADAMTSL3 SVEP1	2.44e-05	182	84	5	44764676ed3f51ba171ce63f669390392fa50a43
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CCN4 TENM3 ADAM33 ADAMTSL3 SVEP1	2.44e-05	182	84	5	d82f59a3f930a840dde27dc6ab024f227a26d446
ToppCell	droplet-Liver-Npc-21m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CCN4 HOXB2 PRICKLE1 NOTCH4 PEAR1	2.44e-05	182	84	5	b1ec2015aad1181eac1bbf8d48ad6f2f7ed24a01
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ADAMTS10 BOC SSC5D ADAM33 GASK1A	2.51e-05	183	84	5	7eae9b3b4d1c9b135fa7cff348393d4adec474b4
ToppCell	Frontal_cortex-Neuronal-Excitatory\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	CACNA1E KLF9 EXTL1 CSMD2 INKA2	2.57e-05	184	84	5	6e17c8151d6dc543de16d804db956c63c3fda414
ToppCell	Adult-Mesenchymal-matrix_fibroblast_2_cell-D122\|Adult / Lineage, Cell type, age group and donor	BOC ADAM33 ADAMTSL3 SVEP1 GASK1A	2.57e-05	184	84	5	2b7e6f91e11c228f0521e099886867d9e998e78d
ToppCell	P28-Mesenchymal-developing_mesenchymal_cell-mesenchymal_myogenic_precursor_(Axin2+)\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	CCN4 HOXB2 ADAMTSL3 TNFRSF21 PEAR1	2.57e-05	184	84	5	23c24ab5786af33d605bc445d06117b9da6c6331
ToppCell	COVID-19-Fibroblasts-Adventitial_FB\|COVID-19 / group, cell type (main and fine annotations)	BOC ADAM33 ADAMTSL3 SVEP1 GASK1A	2.64e-05	185	84	5	a5aebf2b9b05b550d021272731d68af9a6b1229d
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	CACNA1E TENM3 KLF9 EXTL1 INKA2	2.71e-05	186	84	5	56c139e679d640ea901ead657a8e8887e0fca098
ToppCell	droplet-Lung-1m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	BOC CCN4 SSC5D FBLN7 GASK1A	2.78e-05	187	84	5	ed7ab4cf4629d96dad5c74d536fc428d0a8d4eb9
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	BOC PRICKLE1 ADAM33 ADAMTSL3 SVEP1	2.85e-05	188	84	5	ce85a56ac27a6432421dde93a1bafa8b943244b9
ToppCell	TCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Lobular_Carcinoma-6\|TCGA-Breast / Sample_Type by Project: Shred V9	ADAMTS10 SSC5D ADAM33 NOTCH4 PEAR1	2.85e-05	188	84	5	c90669b51e1902fe7726555290c91c92a911df83
ToppCell	E18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CCN4 HOXB2 ADAMTSL3 TNFRSF21 PEAR1	2.85e-05	188	84	5	a906c29e3fda22eecfec3e5cac706c417bf2b7a4
ToppCell	P28-Mesenchymal-developing_mesenchymal_cell\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	CCN4 HOXB2 ADAMTSL3 TNFRSF21 PEAR1	2.85e-05	188	84	5	e7681efb4d2de7f1d8a89552fff76a829376bf1b
ToppCell	E17.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_myogenic_precursor_(Axin2+)\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	CCN4 HOXB2 ADAMTSL3 TNFRSF21 PEAR1	2.93e-05	189	84	5	26cfe5b7e7f477f225f4e9f25f983f432f01e183
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	BOC SSC5D ADAM33 SVEP1 GASK1A	2.93e-05	189	84	5	d531399749409d614adca13d181830c6e3287508
ToppCell	10x5'v1-week_14-16-Mesenchymal_fibro-stroma\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	BOC SSC5D APCDD1L ADAM33 ADAMTSL3	2.93e-05	189	84	5	eccf3d49354a67c94f1ed7c15a98a48a5e8e2ed0
ToppCell	10x5'v1-week_14-16-Mesenchymal_fibro\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	BOC SSC5D APCDD1L ADAM33 ADAMTSL3	2.93e-05	189	84	5	40764f461b8aa1d3a2c5a30590b7fb9307d47d09
ToppCell	PND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CCN4 HOXB2 ADAMTSL3 INKA2 PEAR1	2.93e-05	189	84	5	ca3a04c202afc32aa11d17154066ef7dc6d01405
ToppCell	(2)_Fibroblasts-(22)_Fibro-3\|World / Cell class and subclass of bone marrow stroma cells in homeostatis	CCN4 SSC5D FBLN7 TENM3 ADAM33	3.00e-05	190	84	5	3aed03b87ba2c8d479048c3ceef3ff5e38746c28
ToppCell	facs-SCAT-Fat-24m-Mesenchymal-mesenchymal_progenitor\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BOC EGFR KLF9 ADAM33 SVEP1	3.00e-05	190	84	5	dc7e92f1b18d0f5efec11d09d56ba954d4f8b3bd
ToppCell	E17.5-Mesenchymal-developing_mesenchymal_cell\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	CCN4 HOXB2 ADAMTSL3 TNFRSF21 PEAR1	3.00e-05	190	84	5	2ab604d35456beba71c25511e0f819000e6642d2
ToppCell	facs-SCAT-Fat-24m-Mesenchymal-mesenchymal_stem_cell_of_adipose\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BOC EGFR KLF9 ADAM33 SVEP1	3.00e-05	190	84	5	0bb06df3d5a50416854370f234718c6cec3d773b
ToppCell	PND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CCN4 ADAMTSL3 TNFRSF21 INKA2 PEAR1	3.00e-05	190	84	5	7e4d80a3a7f83b6a50f1d0fe82fb6c242c39d5b0
ToppCell	Adult-Mesenchymal-matrix_fibroblast_2_cell-D175\|Adult / Lineage, Cell type, age group and donor	BOC ADAM33 ADAMTSL3 SVEP1 GASK1A	3.00e-05	190	84	5	7dcca3469f3a3b70db0420cb94f7765f39492f06
ToppCell	PND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CCN4 ADAMTSL3 TNFRSF21 INKA2 PEAR1	3.00e-05	190	84	5	1004e89d99c9d46c78b7d3532d8d4aadb81a96fd
ToppCell	droplet-Kidney-nan-3m-Mesenchymal-fibroblast\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SSC5D ADAMTS4 ADAMTSL3 SVEP1 GASK1A	3.00e-05	190	84	5	f61e21d53f2f7804ac6e40ab6c7f69838aa94d6a
ToppCell	droplet-Kidney-nan-3m-Mesenchymal\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SSC5D FBLN7 ADAMTSL3 SVEP1 GASK1A	3.00e-05	190	84	5	2abeb013bb83c578e67dcb985ba44ca63134950b
ToppCell	facs-SCAT-Fat-24m-Mesenchymal\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BOC EGFR KLF9 ADAM33 SVEP1	3.00e-05	190	84	5	008290bb5c79446681dd6bf354336c57ad0d6f13
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	BOC PRICKLE1 ADAM33 ADAMTSL3 SVEP1	3.00e-05	190	84	5	efb757f11c2809e66ddb48a5c84f5433f111cb7c
ToppCell	E18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CCN4 HOXB2 ADAMTSL3 TNFRSF21 PEAR1	3.00e-05	190	84	5	951e067d14412db67dc3babcdf61e41717d7b429
ToppCell	P03-Mesenchymal-developing_mesenchymal_cell-mesenchymal_myogenic_precursor_(Axin2+)\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	CCN4 HOXB2 ADAMTSL3 TNFRSF21 PEAR1	3.00e-05	190	84	5	979b1476fd2692fde977ce56257315fcfc8a01d5
ToppCell	PND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CCN4 ADAMTSL3 TNFRSF21 INKA2 PEAR1	3.00e-05	190	84	5	7fec459cd2ad12c2923a03d098289337c0a4c1d3
ToppCell	PND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CCN4 ADAMTSL3 TNFRSF21 INKA2 PEAR1	3.00e-05	190	84	5	10b02c62e72bfea9767e3e751011436925da823e
ToppCell	E15.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_myogenic_precursor_(Axin2+)\|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	CCN4 HOXB2 EGFR TNFRSF21 PEAR1	3.00e-05	190	84	5	84fbd5664ec886120963d4f50dfa1fd1851d36c1
ToppCell	P07-Mesenchymal-developing_mesenchymal_cell\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	CCN4 HOXB2 ADAMTSL3 TNFRSF21 PEAR1	3.08e-05	191	84	5	ddbc5f97f2aef19be4ad93db4139876c939b848e
ToppCell	10x5'v1-week_14-16-Mesenchymal_fibro-stroma-arteriolar_fibroblast\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	BOC SSC5D APCDD1L ADAM33 ADAMTSL3	3.08e-05	191	84	5	5271198116343c07202649889057e5774d7fdde3
ToppCell	Control-Stromal_mesenchymal\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	BOC SSC5D ADAM33 SVEP1 GASK1A	3.08e-05	191	84	5	14057205ddb9b4bbc582d1358d13cf36d979a61b
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_chondroblast_(18)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	BOC TENM3 EXTL1 MEGF10 GASK1A	3.08e-05	191	84	5	273c4a757292a9301de0eaeacdec91c9866be229
ToppCell	5'-Adult-LymphNode-Mesenchymal\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	BOC ADAMTS4 EGFR ADAMTSL3 SVEP1	3.08e-05	191	84	5	054e9a79bd1486fd812bc7418fb091664fe3a646
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	BOC SSC5D TENM3 ADAM33 GASK1A	3.08e-05	191	84	5	b133ee1c0e58d00ddd2e4e05b01fd04947524c18
ToppCell	5'-Adult-LymphNode-Mesenchymal-fibroblastic-mLN_Stroma_(FMO2+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	BOC ADAMTS4 EGFR ADAMTSL3 SVEP1	3.16e-05	192	84	5	9479e9859140ba98abfe88414de0b28fc2bf43b7
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_2_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	BOC ADAM33 GRIP2 ADAMTSL3 SVEP1	3.16e-05	192	84	5	8d56e360ebc624ca4cd7f0af4f3cc599c244f134
ToppCell	facs-BAT-Fat-24m-Mesenchymal-mesenchymal_progenitor\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBLN7 EGFR KLF9 ADAMTSL3 SVEP1	3.16e-05	192	84	5	0b3161ce3add9f7457f4cfa5749dbb6501e3ad36
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	BOC CCN4 TENM3 ADAMTSL3 SVEP1	3.16e-05	192	84	5	5105e4b577408b4e1a62d0a44c23c2b830ccad88
ToppCell	facs-BAT-Fat-24m-Mesenchymal-mesenchymal_stem_cell_of_adipose\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBLN7 EGFR KLF9 ADAMTSL3 SVEP1	3.16e-05	192	84	5	61c7ec6171c519b2f3e9ce623669162c0c6ba9f5
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_chondroblast_(18)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	BOC TENM3 NOTUM PRICKLE1 ADAMTSL3	3.16e-05	192	84	5	d0649410cf5eacdb0c1dce70e37c7473ef5fddfa
ToppCell	Fibroblast-D_(Pericyte)\|World / shred on cell class and cell subclass (v4)	CCN4 HOXB2 ADAM33 GRIP2 ADAMTSL3	3.16e-05	192	84	5	8c13c351fcc3d88e8c2ffa017e71ff6272cc6fac
ToppCell	facs-BAT-Fat-24m-Mesenchymal\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBLN7 EGFR KLF9 ADAMTSL3 SVEP1	3.16e-05	192	84	5	24d682e3247a73d349e7776b9e564b6b57f4cb13
ToppCell	5'-Adult-LymphNode-Mesenchymal-fibroblastic\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	BOC ADAMTS4 EGFR ADAMTSL3 SVEP1	3.16e-05	192	84	5	d7faa993f68e530ad55185505384ae155d36c222
ToppCell	P03-Mesenchymal-developing_mesenchymal_cell\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	CCN4 HOXB2 ADAMTSL3 TNFRSF21 PEAR1	3.16e-05	192	84	5	063e119c4b58957643908f667e6cfd6f7517fd03
Disease	NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial measurement	CFHR4 CFHR3	4.67e-05	4	83	2	EFO_0803292
Disease	Autosomal recessive spondylocostal dysostosis	HES7 LFNG	4.67e-05	4	83	2	cv:CN043670
Disease	Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 measurement	SVEP1 PEAR1	4.67e-05	4	83	2	EFO_0803113
Disease	SPONDYLOCOSTAL DYSOSTOSIS, AUTOSOMAL RECESSIVE 3	HES7 LFNG	7.77e-05	5	83	2	C1853296
Disease	Cetuximab response	ERBB2 EGFR	7.77e-05	5	83	2	cv:CN077967
Disease	SPONDYLOCOSTAL DYSOSTOSIS, AUTOSOMAL RECESSIVE 2	HES7 LFNG	7.77e-05	5	83	2	C1837549
Disease	Spondylocostal dysostosis	HES7 LFNG	7.77e-05	5	83	2	cv:C0265343
Disease	Panitumumab response	ERBB2 EGFR	7.77e-05	5	83	2	cv:CN077999
Disease	Head and Neck Neoplasms	ERBB2 EGFR PRAME	1.10e-04	33	83	3	C0018671
Disease	Jarcho-Levin syndrome	HES7 LFNG	1.16e-04	6	83	2	C0265343
Disease	Malignant Head and Neck Neoplasm	ERBB2 EGFR PRAME	2.62e-04	44	83	3	C0278996
Disease	Hemolytic-uremic syndrome	CFHR4 CFHR3	2.78e-04	9	83	2	cv:C0019061
Disease	Atypical hemolytic-uremic syndrome	CFHR4 CFHR3	2.78e-04	9	83	2	cv:C2931788
Disease	Head and Neck Carcinoma	ERBB2 EGFR	3.47e-04	10	83	2	C3887461
Disease	gallbladder neoplasm	ERBB2 EGFR	4.23e-04	11	83	2	C0016978
Disease	Malignant neoplasm of gallbladder	ERBB2 EGFR	4.23e-04	11	83	2	C0153452
Disease	Papilloma	ERBB2 EGFR	5.07e-04	12	83	2	C0030354
Disease	Papillomatosis	ERBB2 EGFR	5.07e-04	12	83	2	C0205875
Disease	Papilloma, Squamous Cell	ERBB2 EGFR	5.07e-04	12	83	2	C0205874
Disease	dementia (is_implicated_in)	NOTCH4 LRP8	5.07e-04	12	83	2	DOID:1307 (is_implicated_in)
Disease	Lung cancer	ERBB2 EGFR	6.96e-04	14	83	2	cv:C0242379
Disease	LUNG CANCER	ERBB2 EGFR	6.96e-04	14	83	2	211980
Disease	Neoplasm of lung	ERBB2 EGFR	6.96e-04	14	83	2	cv:C0024121
Disease	median neuropathy (biomarker_via_orthology)	ERBB2 EGFR	6.96e-04	14	83	2	DOID:571 (biomarker_via_orthology)
Disease	laryngeal squamous cell carcinoma (is_marker_for)	ERBB2 EGFR	1.30e-03	19	83	2	DOID:2876 (is_marker_for)
Disease	Carcinoma of lung	ERBB2 EGFR	1.90e-03	23	83	2	C0684249
Disease	Intrahepatic Cholangiocarcinoma	ERBB2 EGFR	2.07e-03	24	83	2	C0345905
Disease	Head Neoplasms	EGFR PRAME	2.07e-03	24	83	2	C0018675
Disease	Upper Aerodigestive Tract Neoplasms	EGFR PRAME	2.07e-03	24	83	2	C0887900
Disease	Extrahepatic Cholangiocarcinoma	ERBB2 EGFR	2.07e-03	24	83	2	C3805278
Disease	Cancer of Head	EGFR PRAME	2.07e-03	24	83	2	C0751177
Disease	Neck Neoplasms	EGFR PRAME	2.25e-03	25	83	2	C0027533
Disease	Cancer of Neck	EGFR PRAME	2.25e-03	25	83	2	C0746787
Disease	alcohol use disorder (implicated_via_orthology)	ERBB2 EGFR ZNF683 KDM6B	2.26e-03	195	83	4	DOID:1574 (implicated_via_orthology)
Disease	Cholangiocarcinoma	ERBB2 EGFR	2.43e-03	26	83	2	C0206698

Protein segments in the cluster

Peptide	Gene	Start	Entry
GACWLHPHCSFTPRP	CCDC185	56	Q8N715
ARGHCWGPGPTQCVN	ERBB2	516	P04626
GCPKPASRWDCHSNQ	CNTNAP1	486	P78357
LTWSGTPPDCVPHHC	CSMD2	3176	Q7Z408
WNRALPSCHAPCGSR	CSMD3	1751	Q7Z407
PPWLARPCHGNCDPT	CACNA1E	881	Q15878
CDLPEWCNGTSHQCP	ADAM21	471	Q9UKJ8
GCTECRHPNWPNQPD	FBXO10	51	Q9UK96
AGGSCLRWEPHCQQP	APCDD1L	26	Q8NCL9
NHNCHCAPGWAPPFC	ADAM33	666	Q9BZ11
WCPHPRRVSIPGHCC	CCN4	166	O95388
SVPAPSPHCGCCQAW	LINC01600	71	Q96MT4
LEACHGPTCPPEWAA	ADAMTS10	936	Q9H324
CNRHVPCPATWAVGN	ADAMTS7	936	Q9UKP4
PAHRPCGAQPCLSWY	ADAMTS7	1511	Q9UKP4
CPCPALPHFWQLRSH	C9orf152	6	Q5JTZ5
PHWAARNAALPTCCP	RAVER1	566	Q8IY67
VHTGERPFPCTWPDC	KLF9	166	Q13886
AEPRGGWACPRCTLH	CAPN15	141	O75808
GWACPRCTLHNTPVA	CAPN15	146	O75808
GSDCSQPCPPAHWGP	MEGF10	696	Q96KG7
CLPNGTWTGEQPHCR	FBLN7	121	Q53RD9
PGAQHRQCLSGCWPA	ESPNL	676	Q6ZVH7
SIHCHLYPDTPWCPR	LFNG	361	Q8NES3
ACPVSGHVSLCWRPG	IL17REL	226	Q6ZVW7
SPEGPRTQCEHPCWE	INKA2	66	Q9NTI7
WHEGCPARLCVASGP	CRB2	536	Q5IJ48
RCPGCGDHIAPSQIW	LIMK2	11	P53671
GLSCAGAWSSCPPHP	KDM6B	21	O15054
NQVCRSGPCHWPHRS	PCSK7	696	Q16549
CTPGWHGAHCQLPCP	PEAR1	511	Q5VY43
PCPPGHWGENCAQTC	PEAR1	651	Q5VY43
WSGPCASAHDSCPNP	IRF5	346	Q13568
AWEACCHPPEVVPGA	HOXB2	241	P14652
GCPVHLVDSCPWPHC	NOTUM	431	Q6P988
LVDSCPWPHCNPSCP	NOTUM	436	Q6P988
FASRAGPGVCWHPSC	PRICKLE1	141	Q96MT3
HSCNWPGQAPCPGIH	GASK1A	401	Q9UFP1
CHALCSPEGCWGPEP	EGFR	506	P00533
HSPWADGTPCGPAQA	ADAMTS4	486	O75173
HCTQNGWSPAVPCLR	CFHR3	71	Q02985
SCQVSGGDWCPQHPV	BOC	1071	Q9BWV1
PAEPHCWPAEAALGT	CABIN1	2046	Q9Y6J0
WAPHSPCGSPAATEA	LINC00304	41	Q8N9R0
WARGPCCPVHPQSLT	C18orf15	111	Q96N68
PLCPEHSSCTALAWP	CCDC188	196	H7C350
HSSCTALAWPPDPAG	CCDC188	201	H7C350
HCTPQGDWSPAAPRC	CR1L	331	Q2VPA4
DACGQPVPWEHCCPW	FAM120C	836	Q9NX05
GAWPGLPRRPCVHCC	C1QTNF8	16	P60827
CSNGEWSEPPRCIHP	CFHR4	501	Q92496
TCPCGVPACSHVPTW	CRIPAK	171	Q8N1N5
ASGPCPPHADCRDLW	CELSR3	1951	Q9NYQ7
QLHRWDPCVPSCHSP	GRIP2	351	Q9C0E4
SCHSPRPGHCRMPTW	GRIP2	361	Q9C0E4
QGHPSPRCAWSPSLC	HES7	166	Q9BYE0
FWTCPHCGLHAPLTP	DHX34	1066	Q14147
RDNWFCEPCSNPHPL	ZMYND8	266	Q9ULU4
WECATAGSPAHPCFD	PKD1L1	821	Q8TDX9
GHQCLSPPLPSWDSD	CCDC159	261	P0C7I6
RDCNPHCPWRCDGPT	R3HDML	151	Q9H3Y0
PTSHKCVPASWRCDG	LRP8	136	Q14114
SCQNWLPGEPHPATA	PKD1	491	P98161
SQHPLSWCCPIDPAG	PHF20L1	146	A8MW92
PPDLCPCRHSGQWYL	SSPOP	971	A2VEC9
CTAQPCPPPTHCAWS	SSPOP	4151	A2VEC9
PPEECNCWHTSAAGA	SSPOP	4476	A2VEC9
PPTACPCTQHSLPWG	SSPOP	4871	A2VEC9
NATCAPHTVCPVGWG	TNFRSF21	141	O75509
WLSANPCPHCGDRTF	PRAME	481	P78395
GCPQEAHADGSWPPS	SHROOM2	386	Q13796
DCPRSPWGRSNCDHS	SSC5D	276	A1L4H1
QWSSPIPTCHPVSCG	SVEP1	2191	Q4LDE5
GVPDPWKGCPSHSRC	NOTCH4	1206	Q99466
RCGPDHPASRCPWDP	NOTCH4	1391	Q99466
GHPRNLTCSVPWACE	SIGLEC12	286	Q96PQ1
PPQAPHGGSCNWESC	EXTL1	71	Q92935
GSPTRCAHCPVAWAP	SPEM1	116	Q8N4L4
CPCLHVADPAWQGPG	C11orf16	61	Q9NQ32
SQWEGPPRLGCIFCH	PLEKHS1	346	Q5SXH7
PQPAHRFPFGASCWA	PRSS53	146	Q2L4Q9
CINPSNWCDGVSHCP	TMPRSS2	126	O15393
GSCDPSDQCPPQARW	TMEM52	36	Q8NDY8
PPTAPGSQATAWHRC	ZNF575	201	Q86XF7
ECSLGSWCQSPCPHA	SCART1	106	Q4G0T1
GWTGPACNQRACHPR	TENM3	701	Q9P273
APASPACWSDSPGQH	SH2B2	531	O14492
CWPVSPEFGHRCALG	WDR6	1096	Q9NNW5
APPSLRWHQCCQPSD	SLC35G6	21	P0C7Q6
PSRGWDHPVRVCFNC	ZFYVE1	756	Q9HBF4
GSSPCQPHARCSLWR	RELT	61	Q969Z4
VPCQPCSWAPLGTHG	RELT	106	Q969Z4
DAHGPSCASWLCPLP	ZNF683	51	Q8IZ20
IAHWCRCHGYTPPDP	YEATS2	1226	Q9ULM3
CARPAWSPHPAGASE	nan	31	Q8NAQ8
QACNTEPCPPRWHVG	ADAMTSL3	696	P82987
GHPCVQWEPGNRCPG	ADAMTSL3	1541	P82987
GTPEHCPGQCLPWAC	MYOG	56	P15173