Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	translation elongation factor activity	GFM2 EEF1A1 EEF1A1P5 EEF1A2	6.77e-06	20	126	4	GO:0003746
GeneOntologyMolecularFunction	myosin binding	NPHS1 AXL ARFGEF2 ADGRV1 CXCR4 USH2A	1.63e-05	85	126	6	GO:0017022
GeneOntologyMolecularFunction	serine binding	SHMT1 THNSL2	1.18e-04	3	126	2	GO:0070905
GeneOntologyMolecularFunction	pancreatic polypeptide receptor activity	NPY4R2 NPY4R	2.35e-04	4	126	2	GO:0001602
GeneOntologyMolecularFunction	nuclear retinoid X receptor binding	NSD1 NCOR1 NCOR2	3.96e-04	23	126	3	GO:0046965
GeneOntologyCellularComponent	Golgi lumen	PCSK5 MUC19 DAG1 MUC16 MUC5B MUC12 MUC6	4.86e-06	109	128	7	GO:0005796
GeneOntologyCellularComponent	eukaryotic translation elongation factor 1 complex	EEF1A1 EEF1A2	2.21e-04	4	128	2	GO:0005853
GeneOntologyCellularComponent	USH2 complex	ADGRV1 USH2A	2.21e-04	4	128	2	GO:1990696
GeneOntologyCellularComponent	leading edge membrane	JCAD ADGRV1 EEF1A1 CDKL5 TLN1 USH2A GABRA4	3.16e-04	210	128	7	GO:0031256
GeneOntologyCellularComponent	stereocilia ankle link	ADGRV1 USH2A	5.49e-04	6	128	2	GO:0002141
GeneOntologyCellularComponent	stereocilia ankle link complex	ADGRV1 USH2A	5.49e-04	6	128	2	GO:0002142
GeneOntologyCellularComponent	stereocilium membrane	ADGRV1 USH2A	5.49e-04	6	128	2	GO:0060171
GeneOntologyCellularComponent	periciliary membrane compartment	ADGRV1 USH2A	5.49e-04	6	128	2	GO:1990075
GeneOntologyCellularComponent	stereocilia coupling link	ADGRV1 USH2A	1.02e-03	8	128	2	GO:0002139
GeneOntologyCellularComponent	cell leading edge	JCAD INPP5E DAG1 ADGRV1 EEF1A1 CDKL5 CXCR4 TLN1 USH2A GABRA4	1.03e-03	500	128	10	GO:0031252
Domain	VWF_type-D	MUC19 MUC5B FCGBP SUSD2 MUC6	4.90e-08	16	124	5	IPR001846
Domain	VWFD	MUC19 MUC5B FCGBP SUSD2 MUC6	4.90e-08	16	124	5	PS51233
Domain	VWD	MUC19 MUC5B FCGBP SUSD2 MUC6	4.90e-08	16	124	5	SM00216
Domain	VWD	MUC19 MUC5B FCGBP SUSD2 MUC6	4.90e-08	16	124	5	PF00094
Domain	C8	MUC19 MUC5B FCGBP MUC6	8.79e-07	12	124	4	PF08742
Domain	TIL	MUC19 MUC5B FCGBP MUC6	8.79e-07	12	124	4	PF01826
Domain	Unchr_dom_Cys-rich	MUC19 MUC5B FCGBP MUC6	1.26e-06	13	124	4	IPR014853
Domain	C8	MUC19 MUC5B FCGBP MUC6	1.26e-06	13	124	4	SM00832
Domain	TIL_dom	MUC19 MUC5B FCGBP MUC6	1.76e-06	14	124	4	IPR002919
Domain	VWC_out	MUC19 MUC5B FCGBP MUC6	6.64e-06	19	124	4	SM00215
Domain	G_TR_CS	GFM2 EEF1A1 EEF1A2	2.33e-05	9	124	3	IPR031157
Domain	Transl_elong_EF1A_euk/arc	EEF1A1 EEF1A2	4.37e-05	2	124	2	IPR004539
Domain	NPY4_rcpt	NPY4R2 NPY4R	4.37e-05	2	124	2	IPR001933
Domain	N-CoR_GPS2_interact	NCOR1 NCOR2	4.37e-05	2	124	2	IPR031557
Domain	GPS2_interact	NCOR1 NCOR2	4.37e-05	2	124	2	PF15784
Domain	G_TR_1	GFM2 EEF1A1 EEF1A2	7.78e-05	13	124	3	PS00301
Domain	VWF_dom	MUC19 MUC5B FCGBP MUC6	1.70e-04	42	124	4	IPR001007
Domain	EFTu-like_2	GFM2 EEF1A1 EEF1A2	2.17e-04	18	124	3	IPR004161
Domain	GTP_EFTU_D2	GFM2 EEF1A1 EEF1A2	2.17e-04	18	124	3	PF03144
Domain	G_TR_2	GFM2 EEF1A1 EEF1A2	2.17e-04	18	124	3	PS51722
Domain	TF_GTP-bd_dom	GFM2 EEF1A1 EEF1A2	2.56e-04	19	124	3	IPR000795
Domain	SANT	CHD7 NCOR1 NCOR2 CHD6	3.37e-04	50	124	4	SM00717
Domain	SANT/Myb	CHD7 NCOR1 NCOR2 CHD6	3.92e-04	52	124	4	IPR001005
Domain	CT	MUC19 MUC5B MUC6	4.01e-04	22	124	3	SM00041
Domain	FN3_dom	NPHS1 AXL KIAA0319L OBSCN IL22RA2 ROBO3 USH2A	4.95e-04	209	124	7	IPR003961
Domain	Cys_knot_C	MUC19 MUC5B MUC6	5.90e-04	25	124	3	IPR006207
Domain	CTCK_2	MUC19 MUC5B MUC6	5.90e-04	25	124	3	PS01225
Domain	BRK	CHD7 CHD6	6.45e-04	6	124	2	SM00592
Domain	BRK_domain	CHD7 CHD6	6.45e-04	6	124	2	IPR006576
Domain	BRK	CHD7 CHD6	6.45e-04	6	124	2	PF07533
Domain	Transl_B-barrel	GFM2 EEF1A1 EEF1A2	7.44e-04	27	124	3	IPR009000
Domain	Transl_elong_EFTu/EF1A_C	EEF1A1 EEF1A2	1.19e-03	8	124	2	IPR004160
Domain	-	TMEM131 HYDIN	1.19e-03	8	124	2	2.60.40.360
Domain	Calx_beta	ADGRV1 FREM2	1.19e-03	8	124	2	SM00237
Domain	GTP_EFTU_D3	EEF1A1 EEF1A2	1.19e-03	8	124	2	PF03143
Domain	FN3	NPHS1 AXL KIAA0319L OBSCN ROBO3 USH2A	1.48e-03	185	124	6	SM00060
Domain	Calx_beta	ADGRV1 FREM2	1.53e-03	9	124	2	IPR003644
Domain	PapD-like	TMEM131 HYDIN	1.53e-03	9	124	2	IPR008962
Domain	NPY_rcpt	NPY4R2 NPY4R	1.53e-03	9	124	2	IPR000611
Domain	Calx-beta	ADGRV1 FREM2	1.53e-03	9	124	2	PF03160
Domain	Transl_elong_EF1A/Init_IF2_C	EEF1A1 EEF1A2	1.90e-03	10	124	2	IPR009001
Domain	VWC	MUC19 MUC5B FCGBP	2.03e-03	38	124	3	SM00214
Domain	FN3	NPHS1 AXL OBSCN IL22RA2 ROBO3 USH2A	2.14e-03	199	124	6	PS50853
Domain	Dynein_heavy_chain_D4_dom	DNAH14 DNAH12	3.78e-03	14	124	2	IPR024317
Domain	PLAC	PCSK5 ADAMTSL3	3.78e-03	14	124	2	PF08686
Domain	AAA_8	DNAH14 DNAH12	3.78e-03	14	124	2	PF12780
Domain	DHC_fam	DNAH14 DNAH12	4.34e-03	15	124	2	IPR026983
Domain	Dynein_heavy	DNAH14 DNAH12	4.34e-03	15	124	2	PF03028
Domain	Dynein_heavy_dom	DNAH14 DNAH12	4.34e-03	15	124	2	IPR004273
Domain	fn3	NPHS1 AXL OBSCN ROBO3 USH2A	4.54e-03	162	124	5	PF00041
Domain	CTCK_1	MUC19 MUC5B	6.24e-03	18	124	2	PS01185
Pathway	REACTOME_DEFECTIVE_GALNT3_CAUSES_HFTC	MUC16 MUC5B MUC12 MUC6	3.31e-06	16	95	4	M27410
Pathway	REACTOME_DEFECTIVE_C1GALT1C1_CAUSES_TNPS	MUC16 MUC5B MUC12 MUC6	4.31e-06	17	95	4	M27412
Pathway	REACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS	DAG1 MUC16 MUC5B MUC12 ADAMTSL3 MUC6	6.24e-06	68	95	6	M27303
Pathway	REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS	MUC19 MUC16 MUC5B MUC6	1.06e-05	21	95	4	MM15706
Pathway	REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS	MUC16 MUC5B MUC12 MUC6	1.55e-05	23	95	4	M556
Pathway	WP_RETT_SYNDROME	IMPDH2 CDKL5 NCOR1 NCOR2 ACTL6B	1.70e-05	48	95	5	M39759
Pathway	REACTOME_DECTIN_2_FAMILY	MUC16 MUC5B MUC12 MUC6	2.58e-05	26	95	4	M27483
Pathway	REACTOME_DISEASES_OF_GLYCOSYLATION	DAG1 MUC16 MUC5B MUC12 ADAMTSL3 MUC6 ALG12	5.01e-05	143	95	7	M27275
Pathway	REACTOME_O_LINKED_GLYCOSYLATION	MUC19 DAG1 MUC16 MUC5B ADAMTSL3 MUC6	9.26e-05	109	95	6	MM15164
Pathway	REACTOME_O_LINKED_GLYCOSYLATION	DAG1 MUC16 MUC5B MUC12 ADAMTSL3 MUC6	1.02e-04	111	95	6	M27416
Pathway	REACTOME_DISEASES_OF_METABOLISM	DAG1 MUC16 MUC5B MUC12 ADAMTSL3 MTR MUC6 ALG12	2.81e-04	250	95	8	M27554
Pubmed	Expression of Muc19/Smgc gene products during murine sublingual gland development: cytodifferentiation and maturation of salivary mucous cells.	MUC19 MUC16 MUC5B MUC6	2.78e-09	6	130	4	19110483
Pubmed	Mucin gene expression in human laryngeal epithelia: effect of laryngopharyngeal reflux.	MUC19 MUC16 MUC5B MUC12 MUC6	5.56e-09	18	130	5	18834073
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	CKAP5 E2F6 CHD7 LUZP1 SPAG5 YEATS2 NCOR1 NCOR2 KIF14 CHD6 OBI1 TANGO6	6.25e-08	418	130	12	34709266
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	DOCK4 JCAD VPS45 KIAA0319L CKAP5 LUZP1 SPAG5 FAM83H CEP350 NCOR1 TLN1 KIF14 TMEM131 HSD17B4 EXOSC7	7.64e-07	853	130	15	28718761
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	RBM15 GATAD2A IMPDH2 RPP30 CKAP5 CHD7 EEF1A1 BLMH YEATS2 ZBTB34 NCOR1 NCOR2 CDK13 TLN1 NFRKB MKI67 HSD17B4	8.26e-07	1103	130	17	34189442
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	RBM15 GATAD2A RSF1 NSD1 CHD7 LUZP1 EEF1A1 EEF1A1P5 EEF1A2 YEATS2 NCOR1 NCOR2 NFRKB MKI67 PDCD11	3.02e-06	954	130	15	36373674
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	RBM15 GATAD2A IMPDH2 RPP30 RSF1 CKAP5 CHD7 LUZP1 FAM83H BLMH NCOR2 POLR3B UTP15 TLN1 MKI67 PDCD11 EXOC1 ALOX12B	3.08e-06	1353	130	18	29467282
Pubmed	Transcription factor protein interactomes reveal genetic determinants in heart disease.	RBM15 GATAD2A RSF1 CKAP5 CHD7 EEF1A1P5 YEATS2 NCOR1 NCOR2 HSD17B4	3.60e-06	411	130	10	35182466
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	DOCK4 JCAD RBM15 INPP5E CKAP5 LUZP1 FAM83H EEF1A1 EEF1A2 RUSC2 CEP350 FRMD6 KIF14 OBI1	4.50e-06	861	130	14	36931259
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	JCAD GATAD2A AXL RSF1 MUC16 CHD7 CEP350 YEATS2 NCOR1 NCOR2 DNAH12 CHD6	5.28e-06	638	130	12	31182584
Pubmed	Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer.	CEP350 YEATS2 NCOR1 NCOR2 NFRKB MKI67 KIF14	6.32e-06	184	130	7	32908313
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	GPD2 RBM15 GATAD2A IMPDH2 CKAP5 FAM83H EEF1A1 CEP350 BLMH CNNM3 TLN1 MKI67 PDCD11 KIF14 HSD17B4	7.07e-06	1024	130	15	24711643
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	GPD2 JCAD RBM15 LUZP1 IWS1 CEP350 BLMH PHKA1 CNNM3 NCOR1 NCOR2 STYX MKI67 KIF14 HSD17B4	9.40e-06	1049	130	15	27880917
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	IMPA2 VPS45 POLG OBSCN ADGRV1 DNAH14 EEF1A2 YEATS2 NCOR2 SIGIRR CDK13 SLC16A14 PRKD1 CHD6 HSD11B2 ALG12 VPS13B NSMAF	1.14e-05	1489	130	18	28611215
Pubmed	Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.	BTBD10 RPP30 ZFY IWS1 PHKA1 NCOR1 NCOR2 NFRKB CHD6 HSD17B4	1.27e-05	475	130	10	31040226
Pubmed	CREBBP Inactivation Promotes the Development of HDAC3-Dependent Lymphomas.	NCOR1 NCOR2	1.39e-05	2	130	2	27733359
Pubmed	Involvement of protein kinase D in expression and trafficking of ATP7B (copper ATPase).	ATP7B PRKD1	1.39e-05	2	130	2	21189263
Pubmed	eEF1A demonstrates paralog specific effects on HIV-1 reverse transcription efficiency.	EEF1A1 EEF1A2	1.39e-05	2	130	2	30782564
Pubmed	Corepressors (NCoR and SMRT) as well as coactivators are recruited to positively regulated 1α,25-dihydroxyvitamin D3-responsive genes.	NCOR1 NCOR2	1.39e-05	2	130	2	22944139
Pubmed	Role of polymorphic variants of MTR gene A2756G and SHMT1 gene C1420T in the development of prostatic cancer in residents of the Western Siberian Region of Russia.	SHMT1 MTR	1.39e-05	2	130	2	22803112
Pubmed	Aberrant corepressor interactions implicated in PML-RAR(alpha) and PLZF-RAR(alpha) leukemogenesis reflect an altered recruitment and release of specific NCoR and SMRT splice variants.	NCOR1 NCOR2	1.39e-05	2	130	2	21131350
Pubmed	Posttranslational removal of α-dystroglycan N terminus by PC5/6 cleavage is important for uterine preparation for embryo implantation in women.	PCSK5 DAG1	1.39e-05	2	130	2	26077903
Pubmed	Cooperative NCoR/SMRT interactions establish a corepressor-based strategy for integration of inflammatory and anti-inflammatory signaling pathways.	NCOR1 NCOR2	1.39e-05	2	130	2	19299558
Pubmed	Unique forms of human and mouse nuclear receptor corepressor SMRT.	NCOR1 NCOR2	1.39e-05	2	130	2	10077563
Pubmed	The mitotic spindle protein SPAG5/Astrin connects to the Usher protein network postmitotically.	SPAG5 USH2A	1.39e-05	2	130	2	23351521
Pubmed	Analysis of the Expression and Subcellular Distribution of eEF1A1 and eEF1A2 mRNAs during Neurodevelopment.	EEF1A1 EEF1A2	1.39e-05	2	130	2	35741005
Pubmed	Nuclear Receptor Corepressors NCOR1 and SMRT Regulate Metabolism via Intestinal Regulation of Carbohydrate Transport.	NCOR1 NCOR2	1.39e-05	2	130	2	39106294
Pubmed	The role of translation elongation factor eEF1 subunits in neurodevelopmental disorders.	EEF1A1 EEF1A2	1.39e-05	2	130	2	30370994
Pubmed	Evolution of NCoR-1 and NCoR-2 corepressor alternative mRNA splicing in placental mammals.	NCOR1 NCOR2	1.39e-05	2	130	2	31208445
Pubmed	Disease expression in Usher syndrome caused by VLGR1 gene mutation (USH2C) and comparison with USH2A phenotype.	ADGRV1 USH2A	1.39e-05	2	130	2	15671307
Pubmed	Characteristics of Retinitis Pigmentosa Associated with ADGRV1 and Comparison with USH2A in Patients from a Multicentric Usher Syndrome Study Treatrush.	ADGRV1 USH2A	1.39e-05	2	130	2	34638692
Pubmed	[Prognostic values of the clinical, morphological and molecular biological characteristics of colon adenocarcinoma].	CXCR4 MKI67	1.39e-05	2	130	2	26978017
Pubmed	New insights on the interaction between the isoforms 1 and 2 of human translation elongation factor 1A.	EEF1A1 EEF1A2	1.39e-05	2	130	2	26212729
Pubmed	NCoR/SMRT co-repressors cooperate with c-MYC to create an epigenetic barrier to somatic cell reprogramming.	NCOR1 NCOR2	1.39e-05	2	130	2	29531310
Pubmed	The expression levels of the translational factors eEF1A 1/2 correlate with cell growth but not apoptosis in hepatocellular carcinoma cell lines with different differentiation grade.	EEF1A1 EEF1A2	1.39e-05	2	130	2	17825975
Pubmed	Usher's Syndrome Type II: A Comparative Study of Genetic Mutations and Vestibular System Evaluation.	ADGRV1 USH2A	1.39e-05	2	130	2	28653555
Pubmed	Dissecting the expression of EEF1A1/2 genes in human prostate cancer cells: the potential of EEF1A2 as a hallmark for prostate transformation and progression.	EEF1A1 EEF1A2	1.39e-05	2	130	2	22095224
Pubmed	A targeted RNAi screen of the breast cancer genome identifies KIF14 and TLN1 as genes that modulate docetaxel chemosensitivity in triple-negative breast cancer.	TLN1 KIF14	1.39e-05	2	130	2	23479679
Pubmed	Understanding functions of eEF1 translation elongation factors beyond translation. A proteomic approach.	EEF1A1 EEF1A2	1.39e-05	2	130	2	38220433
Pubmed	Structural models of human eEF1A1 and eEF1A2 reveal two distinct surface clusters of sequence variation and potential differences in phosphorylation.	EEF1A1 EEF1A2	1.39e-05	2	130	2	19636410
Pubmed	Regulation of corepressor alternative mRNA splicing by hormonal and metabolic signaling.	NCOR1 NCOR2	1.39e-05	2	130	2	26166430
Pubmed	Cloning of human and mouse brain cDNAs coding for S1, the second member of the mammalian elongation factor-1 alpha gene family: analysis of a possible evolutionary pathway.	EEF1A1 EEF1A2	1.39e-05	2	130	2	7945283
Pubmed	Dimethylation of eEF1A at Lysine 55 Plays a Key Role in the Regulation of eEF1A2 on Malignant Cell Functions of Acute Myeloid Leukemia.	EEF1A1 EEF1A2	1.39e-05	2	130	2	32347192
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	PCSK5 INPP5E POLG KIAA0319L OBSCN NSD1 ARFGEF2 FAM83H GDPD5 NCOR1 NCOR2 DIP2A CDK13 TLN1 PDCD11	1.73e-05	1105	130	15	35748872
Pubmed	Identification and functional characterization of transcriptional activators in human cells.	JCAD GATAD2A SHMT1 CHD7 YEATS2 NCOR2 NFRKB ZNF518B TANGO6	2.00e-05	398	130	9	35016035
Pubmed	Assignment of human elongation factor 1alpha genes: EEF1A maps to chromosome 6q14 and EEF1A2 to 20q13.3.	EEF1A1 EEF1A1P5 EEF1A2	2.25e-05	15	130	3	8812466
Pubmed	HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.	JCAD RBM15 GATAD2A CENPL APOB EEF1A1 CASP12 NCOR2 MKI67 KIF14 CHD6 TANGO6	2.76e-05	754	130	12	35906200
Pubmed	A protein interaction landscape of breast cancer.	DOCK4 IMPDH2 DAG1 MUC5B SPAG5 EEF1A2 FRMD6 TLN1 MKI67 PDCD11 EXOSC7	2.78e-05	634	130	11	34591612
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	RBM15 GATAD2A CKAP5 NSD1 E2F6 CHD7 EEF1A1P5 IWS1 YEATS2 NCOR1 NCOR2 CDK13 NFRKB MKI67 PDCD11 CHD6	2.78e-05	1294	130	16	30804502
Pubmed	The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.	RBM15 GATAD2A IMPDH2 BTBD10 RPP30 CKAP5 POLR3B UTP15 CDK13 MKI67 PDCD11 EXOSC7	2.95e-05	759	130	12	35915203
Pubmed	Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.	RBM15 RSF1 CKAP5 LUZP1 SPAG5 IWS1 CEP350 TLN1 KIF14 EXOC1 CHD6	3.25e-05	645	130	11	25281560
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	RBM15 IMPDH2 RSF1 CKAP5 NSD1 CHD7 UTP15 TLN1 MKI67 PDCD11 KIF14	3.63e-05	653	130	11	22586326
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	VPS45 KIAA0319L ARFGEF2 MUC16 APOB CEP350 CDKL5 CNNM3 CASP12 NCOR1 FRMD6 MKI67	3.70e-05	777	130	12	35844135
Pubmed	A novel p53 regulator, C16ORF72/TAPR1, buffers against telomerase inhibition.	SHMT1 ADGRV1 RUSC2 FREM2 NALF1 MTR PDCD11 KIF14 ALG12	3.73e-05	431	130	9	33660365
Pubmed	Functional interactions with Pit-1 reorganize co-repressor complexes in the living cell nucleus.	NCOR1 NCOR2	4.15e-05	3	130	2	16030140
Pubmed	Predicting Lymph Node Metastasis in Endometrial Cancer Using Serum CA125 Combined with Immunohistochemical Markers PR and Ki67, and a Comparison with Other Prediction Models.	MUC16 MKI67	4.15e-05	3	130	2	27163153
Pubmed	Involvement of SMRT corepressor in transcriptional repression by the vitamin D receptor.	NCOR1 NCOR2	4.15e-05	3	130	2	19098224
Pubmed	The corepressors silencing mediator of retinoid and thyroid hormone receptor and nuclear receptor corepressor are involved in agonist- and antagonist-regulated transcription by androgen receptor.	NCOR1 NCOR2	4.15e-05	3	130	2	16373395
Pubmed	PDZD7 is a modifier of retinal disease and a contributor to digenic Usher syndrome.	ADGRV1 USH2A	4.15e-05	3	130	2	20440071
Pubmed	Nuclear corepressor SMRT is a strong regulator of body weight independently of its ability to regulate thyroid hormone action.	NCOR1 NCOR2	4.15e-05	3	130	2	31404087
Pubmed	Interaction of elongation factor 1-alpha with leucine-rich repeat kinase 2 impairs kinase activity and microtubule bundling in vitro.	EEF1A1 EEF1A2	4.15e-05	3	130	2	19559761
Pubmed	Nuclear receptor co-repressors are required for the histone-deacetylase activity of HDAC3 in vivo.	NCOR1 NCOR2	4.15e-05	3	130	2	23292142
Pubmed	Polymorphisms in methionine synthase, methionine synthase reductase and serine hydroxymethyltransferase, folate and alcohol intake, and colon cancer risk.	SHMT1 MTR	4.15e-05	3	130	2	19776626
Pubmed	Differential Expression of MUC12, MUC16, and MUC20 in Patients with Active and Remission Ulcerative Colitis.	MUC16 MUC12	4.15e-05	3	130	2	26770020
Pubmed	Deacetylase-independent function of HDAC3 in transcription and metabolism requires nuclear receptor corepressor.	NCOR1 NCOR2	4.15e-05	3	130	2	24268577
Pubmed	Risk of colorectal cancer associated with the C677T polymorphism in 5,10-methylenetetrahydrofolate reductase in Portuguese patients depends on the intake of methyl-donor nutrients.	SHMT1 MTR	4.15e-05	3	130	2	18996879
Pubmed	Oligomerization of ETO is obligatory for corepressor interaction.	NCOR1 NCOR2	4.15e-05	3	130	2	11113190
Pubmed	EBV nuclear antigen EBNALP dismisses transcription repressors NCoR and RBPJ from enhancers and EBNA2 increases NCoR-deficient RBPJ DNA binding.	NCOR1 NCOR2	4.15e-05	3	130	2	21518914
Pubmed	The ATP-dependent chromatin remodeling enzymes CHD6, CHD7, and CHD8 exhibit distinct nucleosome binding and remodeling activities.	CHD7 CHD6	4.15e-05	3	130	2	28533432
Pubmed	Cell cycle progression stimulated by tamoxifen-bound estrogen receptor-alpha and promoter-specific effects in breast cancer cells deficient in N-CoR and SMRT.	NCOR1 NCOR2	4.15e-05	3	130	2	15802375
Pubmed	SMRT and NCoR1 fine-tune inflammatory versus tolerogenic balance in dendritic cells by differentially regulating STAT3 signaling.	NCOR1 NCOR2	4.15e-05	3	130	2	36238311
Pubmed	Endogenous epitope tagging of eEF1A2 in mice reveals early embryonic expression of eEF1A2 and subcellular compartmentalisation of neuronal eEF1A1 and eEF1A2.	EEF1A1 EEF1A2	4.15e-05	3	130	2	37429391
Pubmed	Cloning and functional expression of cDNAs encoding human and rat pancreatic polypeptide receptors.	NPY4R2 NPY4R	4.15e-05	3	130	2	8643460
Pubmed	Structural basis for nuclear receptor corepressor recruitment by antagonist-liganded androgen receptor.	NCOR1 NCOR2	4.15e-05	3	130	2	18852122
Pubmed	Non-USH2A mutations in USH2 patients.	ADGRV1 USH2A	4.15e-05	3	130	2	22147658
Pubmed	DUSP28 links regulation of Mucin 5B and Mucin 16 to migration and survival of AsPC-1 human pancreatic cancer cells.	MUC16 MUC5B	4.15e-05	3	130	2	27230679
Pubmed	CXCR4/CXCL12 signaling impacts enamel progenitor cell proliferation and motility in the dental stem cell niche.	CXCR4 MKI67	4.15e-05	3	130	2	26246398
Pubmed	Regulated clearance of histone deacetylase 3 protects independent formation of nuclear receptor corepressor complexes.	NCOR1 NCOR2	4.15e-05	3	130	2	22337871
Pubmed	Equilibrium interactions of corepressors and coactivators with agonist and antagonist complexes of glucocorticoid receptors.	NCOR1 NCOR2	4.15e-05	3	130	2	15016838
Pubmed	Nuclear Receptor CoRepressors, NCOR1 and SMRT, are required for maintaining systemic metabolic homeostasis.	NCOR1 NCOR2	4.15e-05	3	130	2	34390859
Pubmed	Breast cancer risk associated with multigenotypic polymorphisms in folate-metabolizing genes: a nested case-control study in Taiwan.	SHMT1 MTR	4.15e-05	3	130	2	17595805
Pubmed	Targeted next generation sequencing in Italian patients with Usher syndrome: phenotype-genotype correlations.	ADGRV1 USH2A	4.15e-05	3	130	2	29142287
Pubmed	The nucleocapsid protein of severe acute respiratory syndrome coronavirus inhibits cell cytokinesis and proliferation by interacting with translation elongation factor 1alpha.	EEF1A1 EEF1A2	4.15e-05	3	130	2	18448518
Pubmed	RU486-induced glucocorticoid receptor agonism is controlled by the receptor N terminus and by corepressor binding.	NCOR1 NCOR2	4.15e-05	3	130	2	12011091
Pubmed	Proteinase-activated receptors 1 and 2 regulate invasive behavior of human melanoma cells via activation of protein kinase D1.	F2RL1 PRKD1	4.15e-05	3	130	2	21993564
Pubmed	The nuclear receptor corepressor N-CoR regulates differentiation: N-CoR directly interacts with MyoD.	NCOR1 NCOR2	4.15e-05	3	130	2	10406466
Pubmed	Nuclear corepressors NCOR1/NCOR2 regulate B cell development, maintain genomic integrity and prevent transformation.	NCOR1 NCOR2	4.15e-05	3	130	2	36316474
Pubmed	The functional relationship between co-repressor N-CoR and SMRT in mediating transcriptional repression by thyroid hormone receptor alpha.	NCOR1 NCOR2	4.15e-05	3	130	2	18052923
Pubmed	The DFNB31 gene product whirlin connects to the Usher protein network in the cochlea and retina by direct association with USH2A and VLGR1.	ADGRV1 USH2A	4.15e-05	3	130	2	16434480
Pubmed	The transcription factor B-Myb is maintained in an inhibited state in target cells through its interaction with the nuclear corepressors N-CoR and SMRT.	NCOR1 NCOR2	4.15e-05	3	130	2	11997503
Pubmed	Distinct genetic architectures for syndromic and nonsyndromic congenital heart defects identified by exome sequencing.	CDK13 PRKD1	4.15e-05	3	130	2	27479907
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	IMPDH2 VPS45 RPP30 CKAP5 NSD1 CHD7 LUZP1 EEF1A1P5 IWS1 UTP15 CDK13 TLN1 NFRKB PDCD11 KIF14 CHD6 EXOSC7	4.47e-05	1497	130	17	31527615
Pubmed	Elevation of hsa-miR-7-5p level mediated by CtBP1-p300-AP1 complex targets ATXN1 to trigger NF-κB-dependent inflammation response.	GPD2 IMPDH2 CKAP5 NSD1 DIP2A HSD11B2	4.66e-05	171	130	6	36629882
Pubmed	Identification of proximal SUMO-dependent interactors using SUMO-ID.	GATAD2A LUZP1 EEF1A1P5 BLMH YEATS2 NCOR1 NCOR2 TLN1 NFRKB	4.69e-05	444	130	9	34795231
Pubmed	Sox2 cooperates with Chd7 to regulate genes that are mutated in human syndromes.	GATAD2A CHD7 NCOR1 NCOR2	4.74e-05	53	130	4	21532573
Pubmed	Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.	GPD2 IMPDH2 CKAP5 DAG1 MUC5B EEF1A1 IWS1 BLMH NCOR2 FCGBP UTP15 TLN1 PDCD11 EXOC1 HSD17B4 EXOSC7	5.34e-05	1367	130	16	32687490
Pubmed	The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.	KIAA0319L ARFGEF2 DCBLD1 DAG1 APOB BLMH CDKL5 CNNM3 SIGIRR VPS13B	5.85e-05	569	130	10	30639242
Pubmed	Ubiquitin-Independent Disassembly by a p97 AAA-ATPase Complex Drives PP1 Holoenzyme Formation.	RBM15 SPAG5 RUSC2 CDKL5 MKI67 PDCD11 KIF14 TMEM131	6.75e-05	361	130	8	30344098
Pubmed	Genome-scale RNAi screen for host factors required for HIV replication.	GPD2 DCBLD1 MUC5B APOB GABPB2 CXCR4 ZNF552 THNSL2	6.75e-05	361	130	8	18976975
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	DOCK4 RBM15 CHD7 LUZP1 YEATS2 NCOR1 NCOR2 MTR KIF14 OBI1	7.68e-05	588	130	10	38580884
Interaction	FER1L6 interactions	EEF1A1 EEF1A1P5 EEF1A2	8.20e-06	7	126	3	int:FER1L6
Interaction	NUP43 interactions	RBM15 GATAD2A RSF1 MUC19 NSD1 E2F6 SPAG5 IWS1 YEATS2 NCOR1 NCOR2 NFRKB MKI67 PDCD11 CHD6	8.55e-06	625	126	15	int:NUP43
Interaction	PHF21A interactions	CKAP5 E2F6 CHD7 LUZP1 SPAG5 YEATS2 KIF14 EXOC1 CHD6 OBI1 TANGO6	1.05e-05	343	126	11	int:PHF21A
Interaction	ASF1A interactions	GATAD2A NSD1 E2F6 CHD7 YEATS2 NCOR1 NCOR2 NFRKB CHD6	2.72e-05	249	126	9	int:ASF1A
Cytoband	5q13	ADGRV1 F2RL1 GFM2	3.28e-05	22	130	3	5q13
GeneFamily	CD molecules\|Mucins	MUC19 MUC16 MUC5B MUC12 MUC6	2.37e-08	21	77	5	648
GeneFamily	GATA zinc finger domain containing\|Myb/SANT domain containing	CHD7 NCOR1 NCOR2 CHD6	7.60e-05	53	77	4	532
GeneFamily	Fibronectin type III domain containing\|USH2 complex	ADGRV1 USH2A	1.07e-04	4	77	2	1244
GeneFamily	Fibronectin type III domain containing	NPHS1 AXL OBSCN ROBO3 USH2A	6.03e-04	160	77	5	555
GeneFamily	Immunoglobulin like domain containing	NPHS1 AXL ADAMTSL3 SIGIRR ROBO3	1.40e-03	193	77	5	594
GeneFamily	Dyneins, axonemal	DNAH14 DNAH12	2.34e-03	17	77	2	536
GeneFamily	Cyclin dependent kinases	CDKL5 CDK13	5.45e-03	26	77	2	496
Coexpression	GSE27241_WT_VS_RORGT_KO_TH17_POLARIZED_CD4_TCELL_TREATED_WITH_DIGOXIN_UP	ERN1 CKAP5 CHD7 IWS1 CEP350 YEATS2 NCOR1 TLN1 KIF14	2.63e-07	180	128	9	M8239
Coexpression	GSE3920_UNTREATED_VS_IFNB_TREATED_ENDOTHELIAL_CELL_UP	CENPL DCBLD1 ADGRV1 F2RL1 GABPB2 SIGIRR CXCR4 HYDIN	6.53e-06	200	128	8	M6686
ToppCell	E18.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1-AT1_prolif\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	F2RL1 FAM83H FRMD6 GABPB2 UTP15 SUSD2 THNSL2	8.01e-07	175	129	7	711ace94fa9a763c6ae48171a690953f25deebe4
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OBSCN MUC5B APOB ADGRV1 FREM2 USH2A HYDIN	1.12e-06	184	129	7	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OBSCN MUC5B APOB ADGRV1 FREM2 USH2A HYDIN	1.12e-06	184	129	7	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OBSCN MUC5B APOB ADGRV1 FREM2 USH2A HYDIN	1.12e-06	184	129	7	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	TCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Colon_Adenocarcinoma-7\|TCGA-Colorectal / Sample_Type by Project: Shred V9	WWC3 ARFGEF2 PMS2CL RUSC2 GDPD5 FAM217B CHD6	1.29e-06	188	129	7	14bc73cf79c79c9f208369fd8d498e5b26e0114d
ToppCell	Control-Control-Myeloid-immature_Neutrophil\|Control / Disease, condition lineage and cell class	GPD2 CKAP5 ARFGEF2 CHD7 SPAG5 MKI67 KIF14	1.95e-06	200	129	7	118321ac443feb42aee171baccfc4610f00a8822
ToppCell	facs-Pancreas-Exocrine-24m-Epithelial-pancreatic_D_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CENPL PHTF2 DNAAF11 SPAG5 WEE2 HYDIN	6.55e-06	157	129	6	370f44047ef438b8f1124c2c2761c150c0d8c57f
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)-Goblet_(bronchial)_L.0.4.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MUC16 MUC5B ADGRV1 FCGBP MUC6 SLC4A11	1.62e-05	184	129	6	01c19a830348ab0b9c02c1546a439de70ee10f97
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MUC16 MUC5B EEF1A2 FCGBP SLC16A14 SLC4A11	1.77e-05	187	129	6	71d99a1a95d3692a2891da49d4a243bae6e07fd0
ToppCell	cellseq-Epithelial-Epithelial_Glandular-SMG_Basal/Duct\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MUC16 MUC5B FCGBP SLC16A14 HSD11B2 SLC4A11	2.00e-05	191	129	6	30e7cc5f7eadf90ab0900a73fdfe48f9a1adcbfb
ToppCell	cellseq-Epithelial-Epithelial_Glandular-SMG_Basal/Duct-SMG_Basal/Duct\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MUC16 MUC5B FCGBP SLC16A14 HSD11B2 SLC4A11	2.00e-05	191	129	6	41d2f5278f6d5f52a5bdf4f3df70969481c00162
ToppCell	3'-Broncho-tracheal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_acinar_cell-SMG_duct\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MUC16 MUC5B FCGBP SLC16A14 HSD11B2 SLC4A11	2.06e-05	192	129	6	c227ab1914191e839fc39c9adc2080026d4b04fc
ToppCell	droplet-Lung-30m-Hematologic-myeloid-classical_monocyte_proliferating-classical_monocyte_proliferating_l12-14\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	IMPDH2 CENPL NGB SPAG5 MKI67 KIF14	2.06e-05	192	129	6	52d0aa51e3b6ab3608a5f40bdde9f8134b3afd94
ToppCell	3'-Broncho-tracheal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_acinar_cell-SMG_duct-SMG_duct_L.0.6.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MUC16 MUC5B FCGBP SLC16A14 HSD11B2 SLC4A11	2.06e-05	192	129	6	bf187a57a559ab732bb815892af45ca922966ac6
ToppCell	3'-Broncho-tracheal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_acinar_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MUC16 MUC5B FCGBP SLC16A14 HSD11B2 SLC4A11	2.06e-05	192	129	6	f573b2d205bd4d053a548af3fe3ff9de7be0cd2b
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6\|TCGA-Prostate / Sample_Type by Project: Shred V9	RSF1 CKAP5 DAG1 ADGRV1 CEP350 VPS13B	2.12e-05	193	129	6	abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c13-MKI67-CCL5_l\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	CENPL CKAP5 SHMT1 SPAG5 MKI67 KIF14	2.44e-05	198	129	6	6981cd5b1585c8ae6febdf0c4fb83067127f106c
ToppCell	TCGA-Stomach-Primary_Tumor\|TCGA-Stomach / Sample_Type by Project: Shred V9	CENPL CKAP5 SPAG5 MKI67 PDCD11 KIF14	2.51e-05	199	129	6	38f1f612b29feb868322999ceeda78e52447ec4f
ToppCell	TCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma\|TCGA-Stomach / Sample_Type by Project: Shred V9	CENPL CKAP5 SPAG5 MKI67 PDCD11 KIF14	2.51e-05	199	129	6	b10698aee2e6c17bc559eb4f723024141f914b90
ToppCell	LPS_only-Endothelial-Epi-like\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	LDHD SUSD2 MKI67 SLC4A11 GABRA4	3.32e-05	126	129	5	4c598f7bae09aca7a4ecce63dfd6890b26468c73
ToppCell	ileum-Epithelial_Stem_Cells\|ileum / shred on tissue and cell subclass	SHMT1 FREM2 FCGBP MKI67 PDCD11	3.32e-05	126	129	5	a8ed48cbd1e207fd1aaad454fda9f329eb22aa83
ToppCell	LPS_only-Endothelial-Epi-like-Gen_Cap\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	LDHD SUSD2 MKI67 SLC4A11 GABRA4	3.32e-05	126	129	5	e065304f480a5e38532b66508b0ee87cc48bba9b
ToppCell	LPS-antiTNF-Unknown-Endothelial-Pericyte_2\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	AXL ADAMTSL3 SPAG5 MKI67 KIF14	4.14e-05	132	129	5	02491930097b75aaeedab9e8200711b0dc610944
ToppCell	PND01-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_G2M\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CKAP5 ABCA9 SLC16A14 MKI67 KIF14	5.87e-05	142	129	5	be63c48794a227ea55978524c0f5935342fc455e
Disease	developmental and epileptic encephalopathy 33 (implicated_via_orthology)	EEF1A1 EEF1A1P5 EEF1A2	7.42e-08	3	125	3	DOID:0080463 (implicated_via_orthology)
Disease	Idiopathic hypogonadotropic hypogonadism	AXL CHD7 POLR3B	5.78e-05	18	125	3	C0342384
Disease	cholangiocarcinoma (is_marker_for)	MUC16 MUC5B MKI67 MUC6	1.60e-04	64	125	4	DOID:4947 (is_marker_for)
Disease	Muscle Spasticity	ACTL6B CNR1	1.77e-04	5	125	2	C0026838
Disease	CHARGE syndrome (implicated_via_orthology)	CHD7 CHD6	3.69e-04	7	125	2	DOID:0050834 (implicated_via_orthology)
Disease	dilated cardiomyopathy (implicated_via_orthology)	DAG1 EEF1A1 EEF1A1P5 EEF1A2	3.78e-04	80	125	4	DOID:12930 (implicated_via_orthology)
Disease	Epilepsy, Cryptogenic	ERN1 POLG EEF1A2 CDKL5	4.16e-04	82	125	4	C0086237
Disease	Awakening Epilepsy	ERN1 POLG EEF1A2 CDKL5	4.16e-04	82	125	4	C0751111
Disease	Aura	ERN1 POLG EEF1A2 CDKL5	4.16e-04	82	125	4	C0236018
Disease	level of Triacylglycerol (51:3) in blood serum	GATAD2A APOB	7.84e-04	10	125	2	OBA_2045163
Disease	hearing impairment	CHD7 ADGRV1 HSD17B4 USH2A	8.15e-04	98	125	4	C1384666
Disease	type 2 diabetes mellitus (is_implicated_in)	GPD2 KLF11 AXL APOB CNR1	8.26e-04	171	125	5	DOID:9352 (is_implicated_in)
Disease	Gastric Adenocarcinoma	ERN1 AXL WEE2	9.25e-04	45	125	3	C0278701
Disease	Primary Ciliary Dyskinesia	INPP5E DNAAF11 HYDIN	1.05e-03	47	125	3	C4551720
Disease	Congenital neutropenia	VPS45 CXCR4	1.14e-03	12	125	2	C0340970
Disease	Epilepsy	ERN1 POLG EEF1A2 CDKL5	1.21e-03	109	125	4	C0014544
Disease	R-6-hydroxywarfarin measurement	RBM15 NCOR2 NALF1 MTR	1.43e-03	114	125	4	EFO_0803327
Disease	calcium measurement	KLF11 BTBD10 PHTF2 F2RL1 ABCA9 EEF1A1P5 CNNM3 KIF14 TMEM131	1.45e-03	628	125	9	EFO_0004838
Disease	glycoprotein measurement	DAG1 APOB ADGRV1 HYDIN	1.67e-03	119	125	4	EFO_0004555
Disease	ovarian cancer (is_implicated_in)	MUC16 APOB EEF1A2	1.75e-03	56	125	3	DOID:2394 (is_implicated_in)
Disease	smoking behavior, BMI-adjusted waist circumference	PCSK5 NSD1 ARFGEF2 ADAMTSL3	1.83e-03	122	125	4	EFO_0004318, EFO_0007789
Disease	electrocardiography	JCAD PILRB AXL OBSCN E2F6 LUZP1 EEF1A2 NALF1	1.93e-03	530	125	8	EFO_0004327
Disease	Malignant neoplasm of breast	ATP7B OBSCN ARFGEF2 SHMT1 NCOR1 CXCR4 MKI67 FAM217B MTR VPS13B GABRA4 ZNF646	2.06e-03	1074	125	12	C0006142
Disease	Seizures	POLG CDKL5 MTR ACTL6B CNR1	2.41e-03	218	125	5	C0036572
Disease	ovarian neoplasm	ATP7B MUC16 MKI67 ALOX12B	2.58e-03	134	125	4	C0919267
Disease	Malignant neoplasm of ovary	ATP7B MUC16 MKI67 ALOX12B	2.79e-03	137	125	4	C1140680
Disease	type 2 diabetes mellitus (biomarker_via_orthology)	DAG1 CASP12 MKI67 MTR	3.60e-03	147	125	4	DOID:9352 (biomarker_via_orthology)
Disease	sex interaction measurement, bilirubin measurement	F2RL1 FRMD6	3.89e-03	22	125	2	EFO_0004570, EFO_0008343

Protein segments in the cluster

Peptide	Gene	Start	Entry
KHSSTSSRIAKGGVD	BTBD10	31	Q9BSF8
KGKRGGHSSVSTESE	CXCR4	331	P61073
GSVLIKATHVGNDTT	ATP7B	881	P35670
LSSFHETRKTISGVA	ABCA9	826	Q8IUA7
RSTGLVLDSGATHTT	ACTL6B	161	O94805
SSHGERESKLGSATI	ADGRV1	861	Q8WXG9
TNGEHARSDSGKVST	ARFGEF2	251	Q9Y6D5
SRVLEFTKAHTTSTG	HSD11B2	146	P80365
TTDSGKASADTHGRL	CASP12	231	Q6UXS9
HTITIESEGKGSTFA	CHD7	1496	Q9P2D1
SHSGEERAEVAKSGS	CDK13	236	Q14004
DTHRVLASVVGTTGV	ALG12	446	Q9BV10
GTAHTTKVLTTTTTG	MUC5B	2601	Q9HC84
RFGDVSVKISHLSGS	RBM15	196	Q96T37
GVSKVLVSGGSTHNS	NSD1	951	Q96L73
SVSQETLKHSGIGRA	IWS1	646	Q96ST2
RKTNGSIHETATSGG	GOLGA8S	36	H3BPF8
RHSERTVSAGKGSAT	GATAD2A	566	Q86YP4
GGRRKAISTCTSHIT	OR4D11	231	Q8NGI4
NTAVTKVGTSSSGHE	MUC16	7476	Q8WXI7
KSGVSHSETSLVAVV	MUC6	441	Q6W4X9
TGASTTGSKKHDVRS	NCOR2	1461	Q9Y618
RVHLGSVEKSGSTFS	NPHS1	496	O60500
STAHTNGDRLKEGVS	KIF14	611	Q15058
TLSKSTAIISHGTTG	FAM86B2	121	P0C5J1
KGSSVGTGTNLHRDI	PRKD1	546	Q15139
GTSSRSTKLIHGGVR	GPD2	106	P43304
TTGKGISATLHVTSN	NFRKB	1001	Q6P4R8
TVATHAKQGASVASG	NFRKB	1106	Q6P4R8
ITSHFTSGDGKVAER	INPP5E	421	Q9NRR6
TVHTEVSKGSLRLSG	NPY4R	356	P50391
TTSGSAEVHKAITIS	KIAA0319L	216	Q8IZA0
IHEIGAVGATKTERT	PHKA1	986	P46020
EKRTSSAQVEGGVHS	IMPDH2	491	P12268
AGKGHVSDSESRRST	JCAD	61	Q9P266
SIVRVHTKDGSATSG	FREM2	2286	Q5SZK8
KATSITVTGSGSCRH	DAG1	701	Q14118
KRSVISSRGTHSFIS	PCSK5	81	Q92824
VKESGTTESSAVRSG	MUC19	3211	Q7Z5P9
TTEGKTLAAGSAHTE	MUC19	7496	Q7Z5P9
EATTSTGVHRTTVVG	MUC19	7856	Q7Z5P9
SGSSSKVETSGHIRV	FAM217B	311	Q9NTX9
RESSVVQAGGSKKHS	OBI1	406	Q5W0B1
RKGTLSTTGHSTNFV	DNAH12	3051	Q6ZR08
SRGTDLHSKTATTVG	POLG	926	P54098
RKASVGSASTRHVFG	GABRA4	466	P48169
TSGSKEAVASLRRGH	GDPD5	411	Q8WTR4
LTGVAGTQSTHESLK	IL22RA2	16	Q969J5
ISLSGTVTFGAKSHE	AP5M1	401	Q9H0R1
VGKFTRTSGETTHTH	MKI67	1041	P46013
TSGKTTQTHRETAGD	MKI67	2021	P46013
SETSGHTQESLTAGK	MKI67	2686	P46013
LAVGKLTQTSGETTH	MKI67	2856	P46013
VVSNTSGSARVKLGH	EXOSC7	41	Q15024
AKAHGVRVIGSSTLA	IMPA2	196	O14732
STGTRTCTVTEGKHA	OBSCN	241	Q5VST9
TGPVHFTVGKSRSSA	OBSCN	2446	Q5VST9
RSLIGKVDGTSHVTG	F2RL1	36	P55085
VNTDSGKLHVGTSTG	NT5DC4	271	Q86YG4
HSGLIVKEIGSSTSS	FRMD6	496	Q96NE9
HKATLRIGQDGISTS	APOB	1641	P04114
TRGISKHSTSGTDEG	CKAP5	821	Q14008
VITKSKADSHGSGSQ	HYDIN	2151	Q4G0P3
KRSEGVGTSSSESTH	E2F6	246	O75461
SSVFSHGVSITRKLG	DOCK4	376	Q8N1I0
RVSTSVASAHTDGKI	CENPL	306	Q8N0S6
TATGAVAGVALHSSV	ERVK-25	481	P61570
STLDGSLHAVSKRTG	ERN1	36	O75460
RTHTITIQSEGKGST	CHD6	986	Q8TD26
AHLSGADVVVTTTSG	FCGBP	3371	Q9Y6R7
KIDSEGGVSANHTSR	HSD17B4	301	P51659
VVIGHVDSGKSTTTG	EEF1A2	11	Q05639
VVIGHVDSGKSTTTG	EEF1A1	11	P68104
KAVVGGSHVSTAAVV	LDHD	36	Q86WU2
NHSTRSVSAVTKGLE	GLB1L	276	Q6UWU2
LSGHSVSVSSDKGRS	CEP350	1236	Q5VT06
SVSKQESSKGSHRTG	CEP350	2001	Q5VT06
RGTQKSIIIHTSEDG	CNR1	311	P21554
VHSGATKGEISATQD	BLMH	196	Q13867
DSSSAKRSQTTGHLV	DNAAF11	361	Q86X45
IVRRAFKGSASSHTG	DNAH14	3381	Q0VDD8
SDTSSETVFGKRGHV	LUZP1	531	Q86V48
SISLTIVGTQGESHK	ALOX12B	21	O75342
VVIGHVDSGKSTTTG	EEF1A1P5	11	Q5VTE0
RKSRGTSTQGTSTHA	FZD3	546	Q9NPG1
AKISERIQGHTGAVT	NSMAF	876	Q92636
KGTSVIRHTGESPAA	KLF11	171	O14901
SAVKQETESLHGSSG	EXOC1	451	Q9NV70
TSKEGSTVGVTVSHA	DIP2A	516	Q14689
SEVTVRFESGSHISG	DCBLD1	126	Q8N8Z6
GAGAITVASHSKAVV	FAM83H	751	Q6ZRV2
GTSSFHTRQKSEGGV	CDKL5	671	O76039
DISTITGHRGKDIST	RSF1	1051	Q96T23
HRAVGVKLSSFSTVG	NGB	96	Q9NPG2
VTTTTHKTLRGCRAG	SHMT1	251	P34896
HGETRKTAFGIISTV	RPP30	231	P78346
TKVTGSAGTTEPHTR	GABPB2	426	Q8TAK5
HSTPGGTARSIDSTK	RUSC2	71	Q8N2Y8
TVIRGSHNSTGKASI	USH2A	3426	O75445
RKEGTSVLEHTSDGF	UTP15	496	Q8TED0
HTKRTSSLVSLSGLG	SLC4A11	511	Q8NBS3
TGSLSTGTATRVAHQ	SUSD2	696	Q9UGT4
GTSTSHSVGTVFRDL	PHTF2	236	Q8N3S3
VGLKHTATGDTIVSS	GFM2	436	Q969S9
SQTGLVGTKHSTSET	SPAG5	401	Q96R06
AHSTESVKSTGQQGR	SLC16A14	231	Q7RTX9
GETVRSRHTSVVSSG	NCOR1	1441	O75376
LLIGGATTSKTHTAV	MTR	856	Q99707
HTSGVSLGESRSSEV	SIGIRR	371	Q6IA17
REKHVTVVVGTSGDT	THNSL2	131	Q86YJ6
HSAKESTALVVSTGA	MROH2B	486	Q7Z745
SLSVHSGTTGSLKRT	STYX	191	Q8WUJ0
SGTTGSLKRTHEEED	STYX	196	Q8WUJ0
RLLGEKTTTAAGSSH	CNNM3	676	Q8NE01
KTTTAAGSSHSRPGV	CNNM3	681	Q8NE01
GVVSLSVGHSEVSTA	PDCD11	251	Q14690
SVLAGHSRTVSDSIK	TLN1	1631	Q9Y490
SVGRAEASGSLSVHV	ROBO3	331	Q96MS0
DSNTVTQGHTAGRKS	TMEM131	1266	Q92545
THGAGEKENSRTETT	ZNF646	596	O15015
EAHNAKGVTTSRTAT	AXL	206	P30530
GGSGSSSLQVTKHDV	TANGO6	31	Q9C0B7
TVHTEVSKGSLRLSG	NPY4R2	356	P0DQD5
GTVSKHVTVVGELSR	VPS45	326	Q9NRW7
KGAVGASVTSSTHEK	POLR3B	196	Q9NW08
KTRTFIGLEVTSGHA	USB1	166	Q9BQ65
TIAGLRVTESKGHSE	PILRB	166	Q9UKJ0
KLHVSGESSVFSESG	ZNF552	161	Q9H707
SGVSRGTTSFVKHIS	VPS13B	3691	Q7Z7G8
RAEVEKDSGHGSTSV	PMS2CL	101	Q68D20
DTGVSGTHTGSRSTK	WEE2	531	P0C1S8
AHTISISGKTDAVTV	WWC3	751	Q9ULE0
NTGRDTSRITGSHKT	YEATS2	176	Q9ULM3
HSKISVGDVDSVTVG	ZBTB34	126	Q8NCN2
STTDASGFKRHVISI	ZFY	751	P08048
SAHRRSVGQASKGTS	ZNF518B	686	Q9C0D4
LRGETGSVSQSSHAK	ADAMTSL3	1151	P82987
RKTNGSIHETATSGG	GOLGA8CP	36	A6NN73
GVSVTFITGSTATKH	MUC12	196	Q9UKN1
GIVEASTRVHSSTGS	MUC12	1101	Q9UKN1
GIVEASTRVHSSTGS	MUC12	3741	Q9UKN1
GTVEKSGSCHRTSLT	NALF1	391	B1AL88