Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionpoly(A) binding

KHDRBS1 HNRNPDL DDX3X

3.28e-0729103GO:0008143
GeneOntologyMolecularFunctionpoly-purine tract binding

KHDRBS1 HNRNPDL DDX3X

6.97e-0737103GO:0070717
GeneOntologyMolecularFunctionmRNA binding

KHDRBS1 DDX3X HNRNPR DDX3Y RBMXL3

1.09e-05694105GO:0003729
GeneOntologyMolecularFunctionsingle-stranded RNA binding

KHDRBS1 HNRNPDL DDX3X

1.95e-05111103GO:0003727
GeneOntologyMolecularFunctionRNA helicase activity

DDX3X DDX3Y

6.64e-0478102GO:0003724
GeneOntologyMolecularFunctionATP-dependent activity, acting on RNA

DDX3X DDX3Y

6.99e-0480102GO:0008186
GeneOntologyMolecularFunctionsignaling adaptor activity

KHDRBS1 DDX3X

1.80e-03129102GO:0035591
GeneOntologyMolecularFunctionhelicase activity

DDX3X DDX3Y

2.69e-03158102GO:0004386
GeneOntologyBiologicalProcessRNA splicing

KHDRBS1 FAM98A HNRNPR RBMXL3

6.48e-05502104GO:0008380
GeneOntologyBiologicalProcesspositive regulation of translational initiation

KHDRBS1 DDX3X

8.53e-0529102GO:0045948
GeneOntologyBiologicalProcessRNA processing

KHDRBS1 FAM98A DDX3X HNRNPR RBMXL3

3.73e-041500105GO:0006396
GeneOntologyBiologicalProcessmRNA splicing, via spliceosome

KHDRBS1 HNRNPR RBMXL3

5.68e-04358103GO:0000398
GeneOntologyBiologicalProcessRNA splicing, via transesterification reactions with bulged adenosine as nucleophile

KHDRBS1 HNRNPR RBMXL3

5.68e-04358103GO:0000377
GeneOntologyBiologicalProcessRNA splicing, via transesterification reactions

KHDRBS1 HNRNPR RBMXL3

5.87e-04362103GO:0000375
GeneOntologyBiologicalProcessmRNA metabolic process

KHDRBS1 HNRNPDL HNRNPR RBMXL3

6.57e-04917104GO:0016071
GeneOntologyBiologicalProcessregulation of translational initiation

KHDRBS1 DDX3X

8.47e-0491102GO:0006446
GeneOntologyBiologicalProcessregulation of mRNA metabolic process

KHDRBS1 HNRNPR RBMXL3

1.06e-03443103GO:1903311
GeneOntologyBiologicalProcesspositive regulation of plasma membrane bounded cell projection assembly

FAM98A FRMD7

1.54e-03123102GO:0120034
GeneOntologyBiologicalProcessregulation of mRNA splicing, via spliceosome

KHDRBS1 RBMXL3

1.69e-03129102GO:0048024
GeneOntologyBiologicalProcesstranslational initiation

KHDRBS1 DDX3X

1.77e-03132102GO:0006413
GeneOntologyBiologicalProcessmRNA processing

KHDRBS1 HNRNPR RBMXL3

1.98e-03551103GO:0006397
GeneOntologyBiologicalProcesspositive regulation of translation

KHDRBS1 DDX3X

2.31e-03151102GO:0045727
GeneOntologyBiologicalProcesspositive regulation of cellular component biogenesis

FAM98A FRMD7 DDX3X

2.31e-03582103GO:0044089
GeneOntologyBiologicalProcessregulation of mRNA processing

KHDRBS1 RBMXL3

2.52e-03158102GO:0050684
GeneOntologyCellularComponentpole plasm

DDX3X DDX3Y

8.30e-0529102GO:0045495
GeneOntologyCellularComponentgerm plasm

DDX3X DDX3Y

8.30e-0529102GO:0060293
GeneOntologyCellularComponentP granule

DDX3X DDX3Y

8.30e-0529102GO:0043186
GeneOntologyCellularComponentspliceosomal complex

HNRNPR RBMXL3

4.49e-03215102GO:0005681
GeneOntologyCellularComponentgrowth cone

FRMD7 HNRNPR

5.79e-03245102GO:0030426
GeneOntologyCellularComponentsite of polarized growth

FRMD7 HNRNPR

6.16e-03253102GO:0030427
GeneOntologyCellularComponentcytoplasmic ribonucleoprotein granule

DDX3X DDX3Y

6.94e-03269102GO:0036464
GeneOntologyCellularComponentribonucleoprotein granule

DDX3X DDX3Y

7.86e-03287102GO:0035770
GeneOntologyCellularComponentribonucleoprotein complex

DDX3X HNRNPR RBMXL3

1.65e-021194103GO:1990904
GeneOntologyCellularComponentdistal axon

FRMD7 HNRNPR

1.74e-02435102GO:0150034
MousePhenoabnormal bone mineral density of femur

KHDRBS1 IBSP

4.14e-046372MP:0020009
MousePhenoabnormal placental labyrinth vasculature morphology

DDX3X SS18

1.02e-039972MP:0008803
MousePhenoabnormal bone remodeling

KHDRBS1 IBSP

3.25e-0317872MP:0002998
MousePhenoabnormal placenta vasculature

DDX3X SS18

3.77e-0319272MP:0003231
MousePhenoabnormal placenta labyrinth morphology

DDX3X SS18

3.84e-0319472MP:0001716
DomainDEAD_ATP_HELICASE

DDX3X DDX3Y

1.19e-0431102PS00039
DomainRNA-helicase_DEAD-box_CS

DDX3X DDX3Y

1.35e-0433102IPR000629
DomainRRM_1

HNRNPDL HNRNPR RBMXL3

1.54e-04208103PF00076
DomainRNA_helicase_DEAD_Q_motif

DDX3X DDX3Y

1.70e-0437102IPR014014
DomainQ_MOTIF

DDX3X DDX3Y

1.70e-0437102PS51195
DomainRRM

HNRNPDL HNRNPR RBMXL3

1.75e-04217103SM00360
DomainRRM_dom

HNRNPDL HNRNPR RBMXL3

2.00e-04227103IPR000504
DomainRRM

HNRNPDL HNRNPR RBMXL3

2.08e-04230103PS50102
Domain-

HNRNPDL HNRNPR RBMXL3

2.47e-042441033.30.70.330
DomainNucleotide-bd_a/b_plait

HNRNPDL HNRNPR RBMXL3

2.91e-04258103IPR012677
DomainDEAD

DDX3X DDX3Y

6.64e-0473102PF00270
DomainDEAD/DEAH_box_helicase_dom

DDX3X DDX3Y

6.64e-0473102IPR011545
DomainHelicase_C

DDX3X DDX3Y

1.42e-03107102PF00271
DomainHELICc

DDX3X DDX3Y

1.42e-03107102SM00490
DomainHelicase_C

DDX3X DDX3Y

1.45e-03108102IPR001650
DomainDEXDc

DDX3X DDX3Y

1.47e-03109102SM00487
DomainHELICASE_CTER

DDX3X DDX3Y

1.47e-03109102PS51194
DomainHELICASE_ATP_BIND_1

DDX3X DDX3Y

1.47e-03109102PS51192
DomainHelicase_ATP-bd

DDX3X DDX3Y

1.50e-03110102IPR014001
PathwayWP_MRNA_PROCESSING

HNRNPDL DDX3X HNRNPR RBMXL3

6.53e-0545184MM15946
PathwayWP_NOVEL_INTRACELLULAR_COMPONENTS_OF_RIGILIKE_RECEPTOR_PATHWAY

DDX3X DDX3Y

4.91e-046082M39583
PathwayKEGG_RIG_I_LIKE_RECEPTOR_SIGNALING_PATHWAY

DDX3X DDX3Y

6.87e-047182M15913
Pubmed

Loss of TRIM31 promotes breast cancer progression through regulating K48- and K63-linked ubiquitination of p53.

KHDRBS1 HNRNPDL FAM98A DDX3X SS18 HNRNPR

6.12e-1042110634650049
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

KHDRBS1 HNRNPDL FAM98A DDX3X SS18 HNRNPR DDX3Y

1.28e-0995410736373674
Pubmed

Circular RNA circPVT1 promotes nasopharyngeal carcinoma metastasis via the β-TrCP/c-Myc/SRSF1 positive feedback loop.

KHDRBS1 HNRNPDL FAM98A DDX3X HNRNPR

5.49e-0926010536199071
Pubmed

Proteomic dissection of the von Hippel-Lindau (VHL) interactome.

HNRNPDL DDX3X HNRNPR DDX3Y

1.23e-089810421942715
Pubmed

SPOP attenuates migration and invasion of choriocarcinoma cells by promoting DHX9 degradation.

KHDRBS1 FAM98A DDX3X HNRNPR

3.85e-0813010432905556
Pubmed

Landscape of the SOX2 protein-protein interactome.

KHDRBS1 FAM98A DDX3X HNRNPR

4.61e-0813610421280222
Pubmed

TRIM28-mediated nucleocapsid protein SUMOylation enhances SARS-CoV-2 virulence.

KHDRBS1 HNRNPDL FAM98A DDX3X HNRNPR

6.76e-0843010538172120
Pubmed

Proteomic analysis of the cullin 4B interactome using proximity-dependent biotinylation in living cells.

KHDRBS1 HNRNPDL HNRNPR RBMXL3

7.41e-0815310428225217
Pubmed

An azoospermic factor gene, Ddx3y and its paralog, Ddx3x are dispensable in germ cells for male fertility.

DDX3X DDX3Y

7.44e-08210230613052
Pubmed

Sequential inverse dysregulation of the RNA helicases DDX3X and DDX3Y facilitates MYC-driven lymphomagenesis.

DDX3X DDX3Y

7.44e-08210234437837
Pubmed

Gene structure of the human DDX3 and chromosome mapping of its related sequences.

DDX3X DDX3Y

7.44e-08210211710523
Pubmed

Characterization of D1Pas1, a mouse autosomal homologue of the human AZFa region DBY, as a nuclear protein in spermatogenic cells.

DDX3X DDX3Y

7.44e-08210211591417
Pubmed

Structural characterization and expression studies of Dby and its homologs in the mouse.

DDX3X DDX3Y

7.44e-08210216728723
Pubmed

Sexually dimorphic RNA helicases DDX3X and DDX3Y differentially regulate RNA metabolism through phase separation.

DDX3X DDX3Y

7.44e-08210235588748
Pubmed

Comparative Proteomics and Interactome Analysis of the SARS-CoV-2 Nucleocapsid Protein in Human and Bat Cell Lines.

KHDRBS1 HNRNPDL DDX3X HNRNPR

1.08e-0716810439066279
Pubmed

Poly(ADP-ribosyl)ation of BRD7 by PARP1 confers resistance to DNA-damaging chemotherapeutic agents.

KHDRBS1 HNRNPDL FAM98A DDX3X HNRNPR

1.24e-0748610530940648
Pubmed

DNA damage shifts circadian clock time via Hausp-dependent Cry1 stabilization.

KHDRBS1 HNRNPDL DDX3X DDX3Y

1.27e-0717510425756610
Pubmed

Arginine methylation and ubiquitylation crosstalk controls DNA end-resection and homologous recombination repair.

KHDRBS1 HNRNPDL FAM98A DDX3X HNRNPR

2.31e-0755110534728620
Pubmed

Host cell interactome of HIV-1 Rev includes RNA helicases involved in multiple facets of virus production.

KHDRBS1 HNRNPDL DDX3X HNRNPR

2.44e-0720610422174317
Pubmed

The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation.

HNRNPDL FAM98A DDX3X HNRNPR DDX3Y RBMXL3

2.45e-07115310629845934
Pubmed

SARS-CoV-2 spike protein induces endothelial inflammation via ACE2 independently of viral replication.

KHDRBS1 HNRNPDL FAM98A HNRNPR

2.95e-0721610437640791
Pubmed

Global analysis of TDP-43 interacting proteins reveals strong association with RNA splicing and translation machinery.

HNRNPDL FAM98A DDX3X HNRNPR

3.35e-0722310420020773
Pubmed

CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality.

KHDRBS1 HNRNPDL FAM98A DDX3X HNRNPR

3.67e-0760510528977666
Pubmed

C9orf72 protein quality control by UBR5-mediated heterotypic ubiquitin chains.

KHDRBS1 HNRNPDL FAM98A DDX3X HNRNPR DDX3Y

4.08e-07125710637317656
Pubmed

Interactome analyses revealed that the U1 snRNP machinery overlaps extensively with the RNAP II machinery and contains multiple ALS/SMA-causative proteins.

KHDRBS1 HNRNPDL DDX3X HNRNPR

4.80e-0724410429884807
Pubmed

Heterozygous deletion of chromosome 17p renders prostate cancer vulnerable to inhibition of RNA polymerase II.

KHDRBS1 HNRNPDL DDX3X HNRNPR

4.80e-0724410430349055
Pubmed

Identification of proteins associated with ligand-activated estrogen receptor α in human breast cancer cell nuclei by tandem affinity purification and nano LC-MS/MS.

KHDRBS1 DDX3X HNRNPR DDX3Y

4.88e-0724510421182205
Pubmed

A Compendium of RNA-Binding Proteins that Regulate MicroRNA Biogenesis.

FAM98A DDX3X HNRNPR DDX3Y

5.64e-0725410428431233
Pubmed

Cell cycle-dependent phosphorylation regulates RECQL4 pathway choice and ubiquitination in DNA double-strand break repair.

KHDRBS1 HNRNPDL FAM98A DDX3X HNRNPR DDX3Y

5.82e-07133510629229926
Pubmed

PTPN14 regulates Roquin2 stability by tyrosine dephosphorylation.

KHDRBS1 HNRNPDL FAM98A DDX3X HNRNPR

6.45e-0767810530209976
Pubmed

Translational regulation of HIV-1 replication by HIV-1 Rev cellular cofactors Sam68, eIF5A, hRIP, and DDX3.

KHDRBS1 DDX3X

7.44e-07510221360055
Pubmed

Mouse erythroid cells express multiple putative RNA helicase genes exhibiting high sequence conservation from yeast to mammals.

DDX3X DDX3Y

7.44e-0751028144024
Pubmed

Mutual regulation between OGT and XIAP to control colon cancer cell growth and invasion.

KHDRBS1 HNRNPDL FAM98A DDX3X HNRNPR

7.76e-0770410532994395
Pubmed

RNA-binding proteins with basic-acidic dipeptide (BAD) domains self-assemble and aggregate in Alzheimer's disease.

KHDRBS1 HNRNPDL FAM98A DDX3X HNRNPR

8.26e-0771310529802200
Pubmed

Prohibitin 1 regulates tumor cell apoptosis via the interaction with X-linked inhibitor of apoptosis protein.

KHDRBS1 HNRNPDL FAM98A DDX3X HNRNPR

8.97e-0772510527025967
Pubmed

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.

KHDRBS1 HNRNPDL FAM98A DDX3X HNRNPR

1.52e-0680710522681889
Pubmed

USP9X controls translation efficiency via deubiquitination of eukaryotic translation initiation factor 4A1.

FAM98A DDX3X DDX3Y

1.67e-068510329228324
Pubmed

PRP19 transforms into a sensor of RPA-ssDNA after DNA damage and drives ATR activation via a ubiquitin-mediated circuitry.

KHDRBS1 HNRNPDL DDX3X HNRNPR

1.80e-0634010424332808
Pubmed

Quantitative Proteomics Reveals Dynamic Interactions of the Minichromosome Maintenance Complex (MCM) in the Cellular Response to Etoposide Induced DNA Damage.

FAM98A DDX3X HNRNPR DDX3Y RBMXL3

1.89e-0684410525963833
Pubmed

A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain.

KHDRBS1 HNRNPDL HNRNPR RBMXL3

1.95e-0634710416033648
Pubmed

Cleavage and polyadenylation specificity factor 1 (CPSF1) regulates alternative splicing of interleukin 7 receptor (IL7R) exon 6.

HNRNPDL DDX3X HNRNPR

1.98e-069010323151878
Pubmed

Blocking PPARγ interaction facilitates Nur77 interdiction of fatty acid uptake and suppresses breast cancer progression.

FAM98A DDX3X HNRNPR

1.98e-069010333087562
Pubmed

Deubiquitinating enzyme PSMD14 promotes tumor metastasis through stabilizing SNAIL in human esophageal squamous cell carcinoma.

KHDRBS1 FAM98A DDX3X HNRNPR

2.89e-0638310429331416
Pubmed

TNIP2 is a Hub Protein in the NF-κB Network with Both Protein and RNA Mediated Interactions.

KHDRBS1 HNRNPDL FAM98A DDX3X HNRNPR

2.92e-0692210527609421
Pubmed

Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme.

KHDRBS1 HNRNPDL HNRNPR DDX3Y

3.10e-0639010417643375
Pubmed

TDRD3, a novel Tudor domain-containing protein, localizes to cytoplasmic stress granules.

DDX3X DDX3Y

3.34e-061010218632687
Pubmed

Characterization of gene regulation and protein interaction networks for Matrin 3 encoding mutations linked to amyotrophic lateral sclerosis and myopathy.

KHDRBS1 DDX3X HNRNPR

3.54e-0610910329511296
Pubmed

In silico APC/C substrate discovery reveals cell cycle-dependent degradation of UHRF1 and other chromatin regulators.

KHDRBS1 HNRNPDL FAM98A DDX3X HNRNPR

3.76e-0697110533306668
Pubmed

Identification of FUBP1 as a Long Tail Cancer Driver and Widespread Regulator of Tumor Suppressor and Oncogene Alternative Splicing.

KHDRBS1 DDX3X HNRNPR

4.05e-0611410331553912
Pubmed

Maintenance of silent chromatin through replication requires SWI/SNF-like chromatin remodeler SMARCAD1.

KHDRBS1 DDX3X HNRNPR

4.26e-0611610321549307
Pubmed

RioK1, a new interactor of protein arginine methyltransferase 5 (PRMT5), competes with pICln for binding and modulates PRMT5 complex composition and substrate specificity.

HNRNPDL DDX3X HNRNPR DDX3Y

4.36e-0642510421081503
Pubmed

Arginine methylation of SARS-Cov-2 nucleocapsid protein regulates RNA binding, its ability to suppress stress granule formation, and viral replication.

HNRNPDL FAM98A HNRNPR

4.84e-0612110334029587
Pubmed

Cellular proteins and HIV-1 Rev function.

KHDRBS1 DDX3X

4.90e-061210219149558
Pubmed

Targeted and Interactome Proteomics Revealed the Role of PHD2 in Regulating BRD4 Proline Hydroxylation.

KHDRBS1 HNRNPDL DDX3X HNRNPR

5.04e-0644110431239290
Pubmed

ARHGAP24 represses β-catenin transactivation-induced invasiveness in hepatocellular carcinoma mainly by acting as a GTPase-independent scaffold.

KHDRBS1 DDX3X HNRNPR DDX3Y

5.51e-0645110436168627
Pubmed

Interactome Analysis Reveals a Novel Role for RAD6 in the Regulation of Proteasome Activity and Localization in Response to DNA Damage.

HNRNPDL FAM98A HNRNPR

6.15e-0613110328031328
Pubmed

High-sensitivity profiling of SARS-CoV-2 noncoding region-host protein interactome reveals the potential regulatory role of negative-sense viral RNA.

KHDRBS1 HNRNPDL DDX3X HNRNPR

6.43e-0646910437314180
Pubmed

Immunoprecipitation and mass spectrometry defines an extensive RBM45 protein-protein interaction network.

HNRNPDL HNRNPR DDX3Y

6.88e-0613610326979993
Pubmed

LINKIN, a new transmembrane protein necessary for cell adhesion.

KHDRBS1 HNRNPDL DDX3X HNRNPR

7.05e-0648010425437307
Pubmed

Inhibition of calpain 1 restores plasma membrane stability to pharmacologically rescued Phe508del-CFTR variant.

KHDRBS1 HNRNPDL DDX3X DDX3Y

7.52e-0648810431324722
Pubmed

UBE2O promotes lipid metabolic reprogramming and liver cancer progression by mediating HADHA ubiquitination.

KHDRBS1 HNRNPDL FAM98A DDX3Y

7.70e-0649110436273042
Pubmed

Zbtb7b engages the long noncoding RNA Blnc1 to drive brown and beige fat development and thermogenesis.

DDX3X HNRNPR

7.80e-061510228784777
Pubmed

CHK2-BRCA1 tumor-suppressor axis restrains oncogenic Aurora-A kinase to ensure proper mitotic microtubule assembly.

KHDRBS1 HNRNPDL FAM98A HNRNPR

7.89e-0649410426831064
Pubmed

The PRMT5/WDR77 complex regulates alternative splicing through ZNF326 in breast cancer.

KHDRBS1 HNRNPDL HNRNPR

8.69e-0614710328977470
Pubmed

Aberrant cortical development is driven by impaired cell cycle and translational control in a DDX3X syndrome model.

DDX3X DDX3Y

1.14e-051810235762573
Pubmed

Sex differences in sex chromosome gene expression in mouse brain.

DDX3X DDX3Y

1.14e-051810212023983
Pubmed

BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.

HNRNPDL FAM98A DDX3X HNRNPR DDX3Y

1.67e-05131810530463901
Pubmed

Interaction of antiproliferative protein Tob with the CCR4-NOT deadenylase complex.

KHDRBS1 DDX3X

1.71e-052210218377426
Pubmed

The midnolin-proteasome pathway catches proteins for ubiquitination-independent degradation.

KHDRBS1 HNRNPDL DDX3X HNRNPR

1.74e-0560410437616343
Pubmed

Proteomic identification of common SCF ubiquitin ligase FBXO6-interacting glycoproteins in three kinds of cells.

HNRNPDL DDX3X HNRNPR DDX3Y

1.84e-0561310422268729
Pubmed

WWP2 ubiquitylates RNA polymerase II for DNA-PK-dependent transcription arrest and repair at DNA breaks.

KHDRBS1 FAM98A DDX3X HNRNPR

1.87e-0561510431048545
Pubmed

Molecular Characterization of the Oncogene BTF3 and Its Targets in Colorectal Cancer.

KHDRBS1 FAM98A DDX3X HNRNPR

2.00e-0562610433644029
Pubmed

β-Actin mRNA interactome mapping by proximity biotinylation.

KHDRBS1 DDX3Y

2.05e-052410231189591
Pubmed

The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.

KHDRBS1 HNRNPDL DDX3X HNRNPR

2.16e-0563810433239621
Pubmed

Functional coherence of the human Y chromosome.

DDX3X DDX3Y

2.22e-05251029381176
Pubmed

Profiling of Parkin-binding partners using tandem affinity purification.

HNRNPDL DDX3X HNRNPR

2.28e-0520310324244333
Pubmed

Proteomic characterization of chromosomal common fragile site (CFS)-associated proteins uncovers ATRX as a regulator of CFS stability.

KHDRBS1 HNRNPDL DDX3X HNRNPR

2.35e-0565210431180492
Pubmed

MRNIP interacts with sex body chromatin to support meiotic progression, spermatogenesis, and male fertility in mice.

DDX3X DDX3Y

2.41e-052610235920200
Pubmed

The intracellular interactome of tetraspanin-enriched microdomains reveals their function as sorting machineries toward exosomes.

KHDRBS1 DDX3X DDX3Y

2.60e-0521210323463506
Pubmed

Role of the E3 ubiquitin-ligase Hakai in intestinal inflammation and cancer bowel disease.

KHDRBS1 DDX3X

2.60e-052710236266428
Pubmed

KAP1 facilitates reinstatement of heterochromatin after DNA replication.

KHDRBS1 HNRNPDL DDX3X DDX3Y

3.17e-0570410429955894
Pubmed

Mechanistic rationale for inhibition of poly(ADP-ribose) polymerase in ETS gene fusion-positive prostate cancer.

HNRNPDL DDX3X

3.22e-053010221575865
Pubmed

BPA modulates the WDR5/TET2 complex to regulate ERβ expression in eutopic endometrium and drives the development of endometriosis.

KHDRBS1 HNRNPDL DDX3X HNRNPR

3.30e-0571110433022573
Pubmed

A systems-wide screen identifies substrates of the SCFβTrCP ubiquitin ligase.

KHDRBS1 HNRNPDL DDX3X

3.40e-0523210325515538
Pubmed

USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.

KHDRBS1 DDX3X HNRNPR

3.48e-0523410336243803
Pubmed

SARS-CoV-2 N Protein Antagonizes Stress Granule Assembly and IFN Production by Interacting with G3BPs to Facilitate Viral Replication.

KHDRBS1 DDX3X HNRNPR

4.00e-0524510335652658
Pubmed

HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.

KHDRBS1 HNRNPDL FAM98A DDX3X

4.15e-0575410435906200
Pubmed

SLFN11 promotes CDT1 degradation by CUL4 in response to replicative DNA damage, while its absence leads to synthetic lethality with ATR/CHK1 inhibitors.

HNRNPDL DDX3X HNRNPR

4.24e-0525010333536335
Pubmed

SND1 binds SARS-CoV-2 negative-sense RNA and promotes viral RNA synthesis through NSP9.

HNRNPDL DDX3X HNRNPR

4.66e-0525810337794589
Pubmed

Ubiquilin 2 modulates ALS/FTD-linked FUS-RNA complex dynamics and stress granule formation.

KHDRBS1 DDX3X HNRNPR

5.27e-0526910330442662
Pubmed

EZH2 interacts with HP1BP3 to epigenetically activate WNT7B that promotes temozolomide resistance in glioblastoma.

HNRNPDL DDX3X HNRNPR DDX3Y

5.30e-0580310436517590
Pubmed

Unbiased Identification of trans Regulators of ADAR and A-to-I RNA Editing.

HNRNPDL HNRNPR DDX3Y

5.39e-0527110332433965
Pubmed

mTORC1 activity regulates post-translational modifications of glycine decarboxylase to modulate glycine metabolism and tumorigenesis.

KHDRBS1 DDX3X HNRNPR

5.57e-0527410334244482
Pubmed

Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.

KHDRBS1 FAM98A DDX3X HNRNPR

6.52e-0584710435850772
Pubmed

LOXL2 Upregulates Phosphorylation of Ezrin to Promote Cytoskeletal Reorganization and Tumor Cell Invasion.

KHDRBS1 DDX3X HNRNPR

9.41e-0532710331409639
Pubmed

Integrative genomics positions MKRN1 as a novel ribonucleoprotein within the embryonic stem cell gene regulatory network.

FAM98A DDX3X

9.79e-055210226265008
Pubmed

HDAC6 activity is not required for basal autophagic flux in metastatic prostate cancer cells.

DDX3X HNRNPR

9.79e-055210226643866
Pubmed

NudCL2 regulates cell migration by stabilizing both myosin-9 and LIS1 with Hsp90.

HNRNPDL DDX3X HNRNPR

9.93e-0533310332665550
Pubmed

TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.

KHDRBS1 DDX3X HNRNPR DDX3Y

1.01e-0494910436574265
Pubmed

ARIH2 Is a Vif-Dependent Regulator of CUL5-Mediated APOBEC3G Degradation in HIV Infection.

HNRNPDL DDX3X HNRNPR

1.02e-0433610331253590
InteractionTRIM31 interactions

KHDRBS1 HNRNPDL FAM98A DDX3X SS18 HNRNPR

2.46e-08454106int:TRIM31
InteractionMIR20A interactions

FAM98A DDX3X HNRNPR DDX3Y

3.46e-0874104int:MIR20A
InteractionMIR98 interactions

FAM98A DDX3X HNRNPR DDX3Y

4.28e-0878104int:MIR98
InteractionMIR143 interactions

FAM98A DDX3X HNRNPR DDX3Y

4.75e-0880104int:MIR143
InteractionMIR106A interactions

FAM98A DDX3X HNRNPR DDX3Y

5.51e-0883104int:MIR106A
InteractionMIR7-2 interactions

FAM98A DDX3X HNRNPR DDX3Y

5.79e-0884104int:MIR7-2
InteractionMIR31 interactions

FAM98A DDX3X HNRNPR DDX3Y

5.79e-0884104int:MIR31
InteractionMIR107 interactions

FAM98A DDX3X HNRNPR DDX3Y

6.07e-0885104int:MIR107
InteractionMIR18B interactions

FAM98A DDX3X HNRNPR DDX3Y

6.07e-0885104int:MIR18B
InteractionSMC5 interactions

KHDRBS1 HNRNPDL FAM98A DDX3X SS18 HNRNPR DDX3Y

7.63e-081000107int:SMC5
InteractionMIR19B2 interactions

FAM98A DDX3X HNRNPR DDX3Y

9.12e-0894104int:MIR19B2
InteractionMIRLET7F1 interactions

FAM98A DDX3X HNRNPR DDX3Y

9.12e-0894104int:MIRLET7F1
InteractionMIR363 interactions

FAM98A DDX3X HNRNPR DDX3Y

1.04e-0797104int:MIR363
InteractionMIR128-2 interactions

FAM98A DDX3X HNRNPR DDX3Y

1.12e-0799104int:MIR128-2
InteractionMIRLET7B interactions

FAM98A DDX3X HNRNPR DDX3Y

1.22e-07101104int:MIRLET7B
InteractionMIRLET7D interactions

FAM98A DDX3X HNRNPR DDX3Y

1.22e-07101104int:MIRLET7D
InteractionMIR25 interactions

FAM98A DDX3X HNRNPR DDX3Y

1.22e-07101104int:MIR25
InteractionMIR7-1 interactions

FAM98A DDX3X HNRNPR DDX3Y

1.32e-07103104int:MIR7-1
InteractionMIR15B interactions

FAM98A DDX3X HNRNPR DDX3Y

1.32e-07103104int:MIR15B
InteractionMIR34A interactions

FAM98A DDX3X HNRNPR DDX3Y

1.37e-07104104int:MIR34A
InteractionBRD7 interactions

KHDRBS1 HNRNPDL FAM98A DDX3X SS18 HNRNPR

1.84e-07637106int:BRD7
InteractionMIRLET7G interactions

FAM98A DDX3X HNRNPR DDX3Y

2.21e-07117104int:MIRLET7G
InteractionFUS interactions

KHDRBS1 HNRNPDL FAM98A DDX3X SS18 HNRNPR

5.08e-07757106int:FUS
InteractionCRY2 interactions

KHDRBS1 HNRNPDL DDX3X DDX3Y

1.67e-06194104int:CRY2
InteractionRBM14 interactions

KHDRBS1 HNRNPDL DDX3X SS18 HNRNPR

3.44e-06553105int:RBM14
InteractionMIR138-1 interactions

FAM98A DDX3X HNRNPR

4.34e-0668103int:MIR138-1
InteractionMIR9-3 interactions

FAM98A DDX3X HNRNPR

4.73e-0670103int:MIR9-3
InteractionLARP7 interactions

KHDRBS1 HNRNPDL DDX3X HNRNPR DDX3Y RBMXL3

4.85e-061113106int:LARP7
InteractionMIR140 interactions

FAM98A DDX3X HNRNPR

4.94e-0671103int:MIR140
InteractionMIR29B1 interactions

FAM98A DDX3X HNRNPR

5.37e-0673103int:MIR29B1
InteractionMIR18A interactions

FAM98A DDX3X HNRNPR

5.37e-0673103int:MIR18A
InteractionMIR15A interactions

FAM98A DDX3X HNRNPR

5.83e-0675103int:MIR15A
InteractionMIR16-1 interactions

FAM98A DDX3X HNRNPR

6.07e-0676103int:MIR16-1
InteractionMIR7-3 interactions

FAM98A DDX3X HNRNPR

6.07e-0676103int:MIR7-3
InteractionMIR199A2 interactions

FAM98A DDX3X HNRNPR

6.07e-0676103int:MIR199A2
InteractionMIR9-2 interactions

FAM98A DDX3X HNRNPR

6.31e-0677103int:MIR9-2
InteractionMIR200A interactions

FAM98A DDX3X HNRNPR

6.31e-0677103int:MIR200A
InteractionMIR222 interactions

FAM98A DDX3X HNRNPR

6.82e-0679103int:MIR222
InteractionMIR34C interactions

FAM98A DDX3X HNRNPR

6.82e-0679103int:MIR34C
InteractionMIR1-2 interactions

FAM98A DDX3X HNRNPR

6.82e-0679103int:MIR1-2
InteractionMIR145 interactions

FAM98A DDX3X HNRNPR

7.36e-0681103int:MIR145
InteractionMIR10B interactions

FAM98A DDX3X HNRNPR

7.63e-0682103int:MIR10B
InteractionMIR200B interactions

FAM98A DDX3X HNRNPR

8.21e-0684103int:MIR200B
InteractionMIR199A1 interactions

FAM98A DDX3X HNRNPR

8.21e-0684103int:MIR199A1
InteractionMIR16-2 interactions

FAM98A DDX3X HNRNPR

8.51e-0685103int:MIR16-2
InteractionMIR93 interactions

FAM98A DDX3X HNRNPR

8.51e-0685103int:MIR93
InteractionMIR9-1 interactions

FAM98A DDX3X HNRNPR

8.51e-0685103int:MIR9-1
InteractionMIR17 interactions

FAM98A DDX3X HNRNPR

8.51e-0685103int:MIR17
InteractionRC3H2 interactions

KHDRBS1 HNRNPDL FAM98A DDX3X HNRNPR

8.59e-06667105int:RC3H2
InteractionMIR20B interactions

FAM98A DDX3X HNRNPR

8.81e-0686103int:MIR20B
InteractionMIR29A interactions

FAM98A DDX3X HNRNPR

9.12e-0687103int:MIR29A
InteractionMIR141 interactions

FAM98A DDX3X HNRNPR

9.44e-0688103int:MIR141
InteractionMIR29C interactions

FAM98A DDX3X HNRNPR

9.77e-0689103int:MIR29C
InteractionMIR221 interactions

FAM98A DDX3X HNRNPR

1.01e-0590103int:MIR221
InteractionMIR92A2 interactions

FAM98A DDX3X HNRNPR

1.01e-0590103int:MIR92A2
InteractionMIR200C interactions

FAM98A DDX3X HNRNPR

1.04e-0591103int:MIR200C
InteractionMIR128-1 interactions

FAM98A DDX3X HNRNPR

1.08e-0592103int:MIR128-1
InteractionMIR155 interactions

FAM98A DDX3X HNRNPR

1.08e-0592103int:MIR155
InteractionATXN2 interactions

KHDRBS1 FAM98A DDX3X HNRNPR

1.10e-05312104int:ATXN2
InteractionMIR214 interactions

FAM98A DDX3X HNRNPR

1.12e-0593103int:MIR214
InteractionMIR205 interactions

FAM98A DDX3X HNRNPR

1.12e-0593103int:MIR205
InteractionMIRLET7A2 interactions

FAM98A DDX3X HNRNPR

1.23e-0596103int:MIRLET7A2
InteractionSYNCRIP interactions

KHDRBS1 HNRNPDL DDX3X SS18 HNRNPR

1.25e-05721105int:SYNCRIP
InteractionMIRLET7C interactions

FAM98A DDX3X HNRNPR

1.27e-0597103int:MIRLET7C
InteractionMIR21 interactions

FAM98A DDX3X HNRNPR

1.27e-0597103int:MIR21
InteractionMIRLET7F2 interactions

FAM98A DDX3X HNRNPR

1.27e-0597103int:MIRLET7F2
InteractionC9orf72 interactions

KHDRBS1 HNRNPDL FAM98A DDX3X HNRNPR DDX3Y

1.30e-051319106int:C9orf72
InteractionMIR106B interactions

DDX3X HNRNPR DDX3Y

1.31e-0598103int:MIR106B
InteractionCUL4B interactions

KHDRBS1 HNRNPDL DDX3X HNRNPR RBMXL3

1.31e-05728105int:CUL4B
InteractionMIR19A interactions

FAM98A DDX3X HNRNPR

1.39e-05100103int:MIR19A
InteractionMIRLET7A3 interactions

FAM98A DDX3X HNRNPR

1.47e-05102103int:MIRLET7A3
InteractionMIR19B1 interactions

FAM98A DDX3X HNRNPR

1.56e-05104103int:MIR19B1
InteractionCHD3 interactions

KHDRBS1 HNRNPDL FAM98A DDX3X HNRNPR

1.59e-05757105int:CHD3
InteractionMYCN interactions

KHDRBS1 HNRNPDL FAM98A DDX3X SS18 HNRNPR

1.64e-051373106int:MYCN
InteractionMIRLET7E interactions

FAM98A DDX3X HNRNPR

1.65e-05106103int:MIRLET7E
InteractionMIRLET7A1 interactions

FAM98A DDX3X HNRNPR

1.75e-05108103int:MIRLET7A1
InteractionBTRC interactions

KHDRBS1 HNRNPDL FAM98A DDX3X HNRNPR

1.78e-05775105int:BTRC
InteractionMIR34B interactions

FAM98A DDX3X HNRNPR

1.85e-05110103int:MIR34B
InteractionRALY interactions

KHDRBS1 HNRNPDL DDX3X HNRNPR

1.85e-05356104int:RALY
InteractionRECQL4 interactions

KHDRBS1 HNRNPDL FAM98A DDX3X HNRNPR DDX3Y

1.92e-051412106int:RECQL4
InteractionMIRLET7I interactions

FAM98A DDX3X HNRNPR

2.06e-05114103int:MIRLET7I
InteractionCIT interactions

KHDRBS1 HNRNPDL FAM98A HNRNPR DDX3Y RBMXL3

2.24e-051450106int:CIT
InteractionMKRN2 interactions

KHDRBS1 HNRNPDL DDX3X HNRNPR

2.51e-05385104int:MKRN2
InteractionKHDRBS2 interactions

KHDRBS1 HNRNPDL HNRNPR

2.98e-05129103int:KHDRBS2
InteractionEIF4B interactions

HNRNPDL FAM98A DDX3X DDX3Y

2.98e-05402104int:EIF4B
InteractionCAND1 interactions

KHDRBS1 HNRNPDL FAM98A DDX3X HNRNPR

3.55e-05894105int:CAND1
InteractionNUDCD2 interactions

HNRNPDL DDX3X HNRNPR DDX3Y

3.67e-05424104int:NUDCD2
InteractionMALAT1 interactions

KHDRBS1 DDX3X HNRNPR

3.72e-05139103int:MALAT1
InteractionDDX17 interactions

KHDRBS1 HNRNPDL DDX3X HNRNPR

3.74e-05426104int:DDX17
InteractionFXR2 interactions

KHDRBS1 FAM98A DDX3X HNRNPR

3.88e-05430104int:FXR2
InteractionIL7R interactions

HNRNPDL DDX3X HNRNPR

3.88e-05141103int:IL7R
InteractionHEXIM1 interactions

HNRNPDL FAM98A DDX3X HNRNPR DDX3Y

3.93e-05913105int:HEXIM1
InteractionDAZL interactions

HNRNPDL FAM98A HNRNPR

4.22e-05145103int:DAZL
InteractionSNRPC interactions

KHDRBS1 HNRNPDL DDX3X HNRNPR

4.24e-05440104int:SNRPC
InteractionPRMT1 interactions

KHDRBS1 HNRNPDL FAM98A DDX3X HNRNPR

4.27e-05929105int:PRMT1
InteractionOGT interactions

KHDRBS1 HNRNPDL FAM98A DDX3X HNRNPR

4.76e-05950105int:OGT
InteractionTNIP2 interactions

KHDRBS1 HNRNPDL FAM98A DDX3X HNRNPR

4.81e-05952105int:TNIP2
InteractionRBMX interactions

KHDRBS1 HNRNPDL DDX3X HNRNPR

5.09e-05461104int:RBMX
InteractionFBXW11 interactions

KHDRBS1 HNRNPDL DDX3X HNRNPR

5.62e-05473104int:FBXW11
InteractionSNRNP70 interactions

KHDRBS1 HNRNPDL FAM98A DDX3X HNRNPR

5.64e-05984105int:SNRNP70
GeneFamilyRNA binding motif containing

HNRNPDL HNRNPR RBMXL3

8.64e-0521383725
GeneFamilyDEAD-box helicases

DDX3X DDX3Y

1.46e-044282499
CoexpressionBIDUS_METASTASIS_UP

KHDRBS1 HNRNPDL HNRNPR

6.79e-05221103M15866
CoexpressionHAY_BONE_MARROW_PRO_B

KHDRBS1 HNRNPDL HNRNPR

1.75e-04304103M39208
CoexpressionIKEDA_MIR1_TARGETS_UP

DDX3X HNRNPR

1.85e-0454102MM927
CoexpressionIKEDA_MIR1_TARGETS_UP

DDX3X HNRNPR

1.85e-0454102M2372
CoexpressionFISCHER_DREAM_TARGETS

KHDRBS1 HNRNPDL SS18 HNRNPR

3.26e-04969104M149
CoexpressionSAKAI_CHRONIC_HEPATITIS_VS_LIVER_CANCER_UP

HNRNPDL HNRNPR

4.28e-0482102M9224
CoexpressionENK_UV_RESPONSE_KERATINOCYTE_DN

HNRNPDL HNRNPR DDX3Y

6.69e-04481103M3898
CoexpressionONKEN_UVEAL_MELANOMA_DN

HNRNPDL DDX3X SS18

9.02e-04533103M2605
CoexpressionKINSEY_TARGETS_OF_EWSR1_FLII_FUSION_UP

HNRNPDL DDX3X SS18 HNRNPR

9.66e-041290104M80
CoexpressionIWANAGA_CARCINOGENESIS_BY_KRAS_DN

HNRNPR DDX3Y

1.01e-03126102M9362
CoexpressionFLECHNER_BIOPSY_KIDNEY_TRANSPLANT_OK_VS_DONOR_UP

HNRNPDL DDX3X HNRNPR

1.08e-03568103M4023
CoexpressionIWANAGA_CARCINOGENESIS_BY_KRAS_DN

HNRNPR DDX3Y

1.15e-03135102MM753
CoexpressionFOURATI_BLOOD_TWINRIX_AGE_25_83YO_RESPONDERS_VS_POOR_RESPONDERS_0DY_UP

KHDRBS1 DDX3X HNRNPR

1.19e-03587103M40869
CoexpressionBROWNE_HCMV_INFECTION_14HR_UP

DDX3X DDX3Y

1.53e-03156102M17225
CoexpressionGSE5589_WT_VS_IL10_KO_LPS_STIM_MACROPHAGE_180MIN_UP

SS18 HNRNPR

1.65e-03162102M6673
CoexpressionBUSSLINGER_GASTRIC_IMMUNE_CELLS

KHDRBS1 HNRNPDL DDX3X DDX3Y

1.66e-031492104M40023
CoexpressionGSE25146_UNSTIM_VS_HELIOBACTER_PYLORI_LPS_STIM_AGS_CELL_DN

DDX3X HNRNPR

1.74e-03166102M8129
CoexpressionGSE3920_IFNA_VS_IFNG_TREATED_ENDOTHELIAL_CELL_UP

HNRNPDL DDX3Y

1.82e-03170102M6697
CoexpressionSNF5_DN.V1_UP

DDX3X DDX3Y

1.88e-03173102M2718
CoexpressionGSE32034_UNTREATED_VS_ROSIGLIZATONE_TREATED_LY6C_LOW_MONOCYTE_UP

IBSP FRMD7

2.33e-03193102M9056
CoexpressionGSE11864_UNTREATED_VS_CSF1_IFNG_IN_MAC_UP

HNRNPDL DDX3Y

2.38e-03195102M3124
CoexpressionGSE22611_UNSTIM_VS_2H_MDP_STIM_NOD2_TRANSDUCED_HEK293T_CELL_DN

HNRNPDL FAM98A

2.46e-03198102M8152
CoexpressionGSE37301_COMMON_LYMPHOID_PROGENITOR_VS_PRO_BCELL_UP

IBSP DDX3X

2.46e-03198102M8866
CoexpressionGSE3982_NEUTROPHIL_VS_BCELL_DN

KHDRBS1 SS18

2.46e-03198102M5521
CoexpressionGSE12366_PLASMA_CELL_VS_NAIVE_BCELL_DN

HNRNPDL HNRNPR

2.48e-03199102M3175
CoexpressionGSE41867_NAIVE_VS_DAY15_LCMV_ARMSTRONG_EFFECTOR_CD8_TCELL_DN

HNRNPDL DDX3X

2.48e-03199102M9501
CoexpressionGSE17721_LPS_VS_GARDIQUIMOD_6H_BMDC_DN

HNRNPDL SS18

2.48e-03199102M4055
CoexpressionGSE27786_NKTCELL_VS_ERYTHROBLAST_UP

KHDRBS1 DDX3X

2.48e-03199102M4865
CoexpressionGSE26156_DOUBLE_POSITIVE_VS_CD4_SINGLE_POSITIVE_THYMOCYTE_UP

HNRNPDL DDX3X

2.48e-03199102M8298
CoexpressionGSE16386_IL4_VS_IL4_AND_ROSIGLITAZONE_STIM_MACROPHAGE_6H_UP

FAM98A DDX3X

2.48e-03199102M8000
CoexpressionGSE17721_CTRL_VS_POLYIC_1H_BMDC_UP

HNRNPDL FAM98A

2.50e-03200102M3707
CoexpressionGSE14769_UNSTIM_VS_240MIN_LPS_BMDM_UP

SS18 HNRNPR

2.50e-03200102M3507
CoexpressionGSE24574_BCL6_HIGH_TFH_VS_TFH_CD4_TCELL_DN

HNRNPDL DDX3X

2.50e-03200102M8331
CoexpressionGSE43955_1H_VS_42H_ACT_CD4_TCELL_UP

DDX3X DDX3Y

2.50e-03200102M9663
CoexpressionGSE27859_DC_VS_CD11C_INT_F480_HI_MACROPHAGE_UP

KHDRBS1 HNRNPDL

2.50e-03200102M8597
CoexpressionGSE41176_WT_VS_TAK1_KO_ANTI_IGM_STIM_BCELL_6H_UP

SS18 HNRNPR

2.50e-03200102M9942
CoexpressionGSE22103_UNSTIM_VS_GMCSF_AND_IFNG_STIM_NEUTROPHIL_UP

KHDRBS1 SS18

2.50e-03200102M7789
CoexpressionGSE17721_CTRL_VS_GARDIQUIMOD_0.5H_BMDC_UP

HNRNPDL DDX3X

2.50e-03200102M3774
CoexpressionGSE411_WT_VS_SOCS3_KO_MACROPHAGE_DN

KHDRBS1 SS18

2.50e-03200102M5991
CoexpressionGSE5589_UNSTIM_VS_45MIN_LPS_AND_IL10_STIM_MACROPHAGE_DN

KHDRBS1 HNRNPR

2.50e-03200102M6603
CoexpressionGSE9006_TYPE_1_DIABETES_AT_DX_VS_1MONTH_POST_DX_PBMC_UP

DDX3X HNRNPR

2.50e-03200102M5783
CoexpressionGSE9006_HEALTHY_VS_TYPE_1_DIABETES_PBMC_1MONTH_POST_DX_UP

DDX3X HNRNPR

2.50e-03200102M5777
CoexpressionGSE17721_POLYIC_VS_PAM3CSK4_12H_BMDC_DN

HNRNPDL HNRNPR

2.50e-03200102M3841
CoexpressionGSE29164_UNTREATED_VS_CD8_TCELL_TREATED_MELANOMA_DAY3_UP

DDX3X DDX3Y

2.50e-03200102M8489
CoexpressionGSE21360_NAIVE_VS_QUATERNARY_MEMORY_CD8_TCELL_DN

HNRNPDL FAM98A

2.50e-03200102M7618
CoexpressionGSE27434_WT_VS_DNMT1_KO_TREG_DN

HNRNPR DDX3Y

2.50e-03200102M9621
CoexpressionGSE46606_UNSTIM_VS_CD40L_IL2_IL5_DAY1_STIMULATED_BCELL_DN

HNRNPDL FAM98A

2.50e-03200102M9864
CoexpressionGSE5099_MONOCYTE_VS_CLASSICAL_M1_MACROPHAGE_DN

KHDRBS1 HNRNPDL

2.50e-03200102M6587
CoexpressionGSE34515_CD16_POS_MONOCYTE_VS_DC_UP

KHDRBS1 HNRNPDL

2.50e-03200102M8765
CoexpressionGSE17721_CTRL_VS_LPS_1H_BMDC_UP

HNRNPDL DDX3Y

2.50e-03200102M3683
CoexpressionGSE22589_HEALTHY_VS_HIV_INFECTED_DC_UP

FAM98A HNRNPR

2.50e-03200102M7805
CoexpressionDESCARTES_ORGANOGENESIS_STROMAL_CELLS

KHDRBS1 DDX3X

2.53e-03201102MM3652
CoexpressionHOLLMANN_APOPTOSIS_VIA_CD40_UP

SS18 DDX3Y

2.58e-03203102M9695
CoexpressionOSWALD_HEMATOPOIETIC_STEM_CELL_IN_COLLAGEN_GEL_UP

HNRNPDL DDX3Y

3.13e-03224102M12383
CoexpressionAtlasDevelopingGonad_e16.5_epididymis_emap-29702_k-means-cluster#5_top-relative-expression-ranked_200

HNRNPR DDX3Y

8.05e-0529102gudmap_developingGonad_e16.5_epididymis_200_k5
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_M-vs-F_top274_274

KHDRBS1 HNRNPDL DDX3Y

1.95e-04256103gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_250_M-vs-F
CoexpressionAtlasDevelopingGonad_P2_epididymis_emap-30199_k-means-cluster#4_top-relative-expression-ranked_500

HNRNPR DDX3Y

2.72e-0453102gudmap_developingGonad_P2_epididymis_500_k4
CoexpressionAtlasDevelopingGonad_e18.5_epididymis_emap-13166_k-means-cluster#2_top-relative-expression-ranked_500

HNRNPR DDX3Y

3.96e-0464102gudmap_developingGonad_e18.5_epididymis_500_k2
CoexpressionAtlasDevelopingGonad_P2_testes_emap-30171_k-means-cluster#2_top-relative-expression-ranked_1000

DDX3X HNRNPR DDX3Y

4.85e-04349103gudmap_developingGonad_P2_testes_1000_k2
CoexpressionAtlasDevelopingGonad_e16.5_testes_emap-8444_k-means-cluster#3_top-relative-expression-ranked_1000

DDX3X HNRNPR DDX3Y

6.12e-04378103gudmap_developingGonad_e16.5_testes_1000_k3
CoexpressionAtlasDevelopingGonad_e16.5_epididymis_emap-29702_k-means-cluster#4_top-relative-expression-ranked_500

HNRNPR DDX3Y

7.99e-0491102gudmap_developingGonad_e16.5_epididymis_500_k4
ToppCellmegakaryocytic-CD34+_Megakaryoblast|megakaryocytic / Lineage and Cell class

KHDRBS1 HNRNPDL HNRNPR

1.00e-0519910399a65887d3c8a2cde26693dd74404b101bba9d58
ToppCellStriatum-Macroglia-POLYDENDROCYTE-P5-P5_1-Sox4-POLYDENDROCYTE_(Rostral-�migratory_stream-�(RMS)_(Stmn2))|Striatum / BrainAtlas - Mouse McCarroll V32

KHDRBS1 IBSP

1.76e-04901027efc3437489c8587b9805547da1095f50d20cf6d
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sncg-Sncg_Slc17a8|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

IBSP FRMD7

1.92e-04941020dc7e645149fa4255cbe1d288524a1ca7ab66376
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Krt73|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

IBSP FRMD7

2.31e-04103102780a94c27ac3eb138a9f284251ae094d3e97ce71
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sncg-Sncg_Vip_Itih5|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

IBSP FRMD7

2.83e-041141029f0c8dfd740d50448a6c91a00e7bae4dfc9b3302
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sncg-Sncg_Vip_Itih5|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

IBSP FRMD7

2.93e-04116102605bd4fdf547cc41783e99cd78425760ef6461ef
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sncg|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

IBSP FRMD7

3.84e-04133102840e8240db29cd21ed9830843c0fa6d65b8f300a
ToppCellHippocampus-Macroglia-POLYDENDROCYTE-P5-P5_2-Sox4|Hippocampus / BrainAtlas - Mouse McCarroll V32

KHDRBS1 HNRNPR

4.02e-041361020185486c39700dd2f72d79be6d283494dd8379c9
ToppCellHippocampus-Macroglia-POLYDENDROCYTE-P5-P5_2|Hippocampus / BrainAtlas - Mouse McCarroll V32

KHDRBS1 HNRNPR

4.02e-041361023e13dc0634f3b05e9f9e6c3193f843f62e603b78
ToppCellEntopeduncular-Endothelial-MURAL-M1(Rgs5Acta2)-M1_1-MURAL_Mural.Rgs5Acta2.Junb_(Mural,_IEG+)-|Entopeduncular / BrainAtlas - Mouse McCarroll V32

HNRNPR DDX3Y

5.28e-041561025df19a235843829f5a1a90ca21b0964ef8b4e115
ToppCellEntopeduncular-Endothelial-MURAL-M1(Rgs5Acta2)-M1_1-MURAL_Mural.Rgs5Acta2.Junb_(Mural,_IEG+)|Entopeduncular / BrainAtlas - Mouse McCarroll V32

HNRNPR DDX3Y

5.28e-04156102029ba0832ee9c4a2c85620e4df2260e02d86b45c
ToppCellTCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Adenocarcinoma_Mixed_Subtype-2|TCGA-Lung / Sample_Type by Project: Shred V9

KHDRBS1 HNRNPR

5.41e-041581029dea15b28f64206bac0e785df6f36a2cc9010ac7
ToppCellIIF|World / Disease, Lineage and Cell Type

HNRNPDL DDX3Y

6.19e-04169102ebf726f725079317ad67c2f754748b4112607277
ToppCell3'_v3-lymph-node_spleen|World / Manually curated celltypes from each tissue

DDX3X DDX3Y

6.33e-041711027aae88da5b37c20f10118325a048f08906be994c
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L1-2_PVALB_TAC1|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

IBSP FRMD7

6.86e-041781021985271984e6747941c8d2097d9c58f0260f021a
ToppCellHippocampus-Macroglia-POLYDENDROCYTE-P5|Hippocampus / BrainAtlas - Mouse McCarroll V32

KHDRBS1 HNRNPR

7.01e-0418010244988c34861df359a68376500c42a64fbcc4b431
ToppCelldroplet-Marrow-BM|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HNRNPDL DDX3Y

7.09e-041811024169a1527b9c8f5783b8cc44e3a3924f8ed9a5e2
ToppCelldroplet-Spleen-nan-18m|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HNRNPDL DDX3X

7.17e-04182102eeb5dfa4539e9ca5220f26bc2b65717ddcf13b6c
ToppCell10x5'v1-week_12-13-Mesenchymal_osteo-stroma-osteoblast|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

IBSP FRMD7

7.17e-04182102ba066ff9029cc052b76e2330ec168cb2e9b7e498
ToppCell10x3'2.3-week_17-19-Mesenchymal_osteo-stroma-early_osteoblast|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

IBSP FRMD7

7.25e-0418310227a57cd8ea924420e182f3d72f5b29b00dea8fa0
ToppCellHippocampus-Macroglia-POLYDENDROCYTE|Hippocampus / BrainAtlas - Mouse McCarroll V32

KHDRBS1 HNRNPR

7.65e-041881028bd6f2cd1aadbd6f9ed31b160f59c1eff144e1dc
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51|PBMC_fresh-frozen / Compartment, severity and other cell annotations on 10x 3' data (130k)

HNRNPDL DDX3X

7.73e-041891020e8d1be3c406d1a393e18faccfe89116a8f82bcf
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-PMP-PMP_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HNRNPDL IBSP

7.73e-041891023169476f98b7385706cb618c9ad64ae83a290ef0
ToppCellH1299-infected-SARSCoV1|infected / Cell line, Condition and Strain

KHDRBS1 HNRNPR

7.81e-04190102f7bfeefc0f30f81710a5ddd979f19b0c910c4a42
ToppCellCOVID-19_Severe-CD8+_T_activated|World / disease group, cell group and cell class

HNRNPDL DDX3Y

8.05e-04193102ddc1db516568e03be8e82b2ca770c67756418185
ToppCellfacs-Thymus-nan-3m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DDX3X DDX3Y

8.14e-0419410266c056232ac216780acf4cc8ea325bd8ed1909c9
ToppCellfacs-Thymus-nan|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DDX3X DDX3Y

8.14e-04194102cda1b197efb199330ea7ab25a7cee22cae22589d
ToppCellfacs-Thymus-nan-3m|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DDX3X DDX3Y

8.14e-04194102f1661f9f2439fca5c1012c693b0744c4e3b90a9b
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_anti-infl-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

DDX3X DDX3Y

8.14e-041941025022c85ad3b137dae4b9ff11f9c23bb3bf4c0f5a
ToppCellfacs-Thymus-nan-3m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DDX3X DDX3Y

8.22e-0419510279114b3c78cc15c413bb58f0673e7215b784a9b6
ToppCellControl-Classical_Monocyte-cMono_2|Control / Disease condition and Cell class

DDX3X DDX3Y

8.22e-041951020fea64ee3eedf3929abb0dd9c5f5fc72f181eed9
ToppCelldroplet-Marrow-BM-1m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HNRNPDL DDX3Y

8.22e-04195102637b06ef3967b03f7165d102d316e8b7161a817d
ToppCell3'_v3-GI_small-bowel-Lymphocytic_T_CD8-Trm_gut_CD8|GI_small-bowel / Manually curated celltypes from each tissue

HNRNPDL DDX3X

8.30e-04196102528622874692d7d65c905738b078ab53acef5846
ToppCellMegakaryocytic-erythropoietic-MEP-MEP|Megakaryocytic-erythropoietic / Lineage, cell class and subclass

KHDRBS1 HNRNPDL

8.30e-041961024e97010185fa9392da8f69e7b2a7395bf063f8ff
ToppCellCOVID-19_Severe|World / Disease condition and Cell class

HNRNPR DDX3Y

8.30e-04196102450ac2aff89c5ca73b8bfbc80663e03be066931f
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-lymphocytic-T_lymphocytic-CD4-positive,_alpha-beta_T_cell|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

HNRNPDL DDX3Y

8.30e-04196102c647ce58de4c5bb4ceb1123690e637eae4ae1b82
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-3m|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KHDRBS1 DDX3X

8.30e-04196102151f1a29a91f8b234e9b6ed062666357a2f69128
ToppCellMegakaryocytic-erythropoietic-MEP|Megakaryocytic-erythropoietic / Lineage, cell class and subclass

KHDRBS1 HNRNPDL

8.30e-04196102f90e7fe3a7b2fff30d01a25cc500876861c2e4f1
ToppCellControl-Classical_Monocyte-cMono_2|Classical_Monocyte / Disease condition and Cell class

DDX3X DDX3Y

8.39e-04197102eb7610c9496a95a5fd866e16abcbc39b83abe617
ToppCell10x5'v1-week_14-16-Lymphocytic_B-B_lineage|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

HNRNPDL HNRNPR

8.39e-041971027290f05d0b8465637420119941bcbf2fae44a7e4
ToppCell10x3'2.3-week_17-19|World / cell types per 3 fetal stages;per 3',per 5'

DDX3X DDX3Y

8.39e-04197102f5cfad0b42d0f817e22cc78b9bfb2b4b7e4330ed
ToppCell10x3'2.3-week_12-13-Lymphocytic_B-B_lineage-pre_B_progenitor|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

HNRNPDL HNRNPR

8.39e-04197102106b0f9a0425facc634feb7498c9ba2c55edfbf8
ToppCell10x5'v1-week_14-16-Lymphocytic_B|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

HNRNPDL HNRNPR

8.39e-0419710231dfd9842410b5c629f39b5130233995dceb0aef
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-PMP|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HNRNPDL IBSP

8.47e-04198102148f5fee19ea8dff7f2de4ca69c3b03e5221985d
ToppCell356C-Lymphocytic-NK_cells-NK_cell_A|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

HNRNPDL DDX3X

8.47e-04198102ec115c4a5dbc54206c72140aa0c8d6a7c29c5563
ToppCell(05)_Secretory-(2)_GFP_FOXI1|(05)_Secretory / shred by cell type by condition

KHDRBS1 DDX3Y

8.56e-04199102d72d87e1e530ed894c0ad5e7b5b2b1d6b59fa098
ToppCellwk_08-11-Mesenchymal-Fibroblast-Early_fibro|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

KHDRBS1 HNRNPDL

8.56e-04199102d67f5ae05daf942fb79f5b962021f37f4e275f4d
ToppCell10x3'2.3-week_12-13-Lymphocytic_B|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

HNRNPDL HNRNPR

8.56e-04199102cdee798e3586e4e7a15de598239090a85752ea1e
ToppCell10x5'v1-week_12-13-Lymphocytic_B|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

HNRNPDL HNRNPR

8.56e-04199102713dfd8552635645db5e0b5721c64e5c9b4aa06c
ToppCell10x5'v1-week_12-13-Lymphocytic_B-B_lineage|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

HNRNPDL HNRNPR

8.56e-04199102ea75804c34989c99aab542e6d72617ed144819b6
ToppCell10x5'v1-week_12-13-Lymphocytic_B-B_lineage-pre_pro_B_progenitor|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

HNRNPDL HNRNPR

8.56e-041991025478b78349b5d8d57f30bb650dcbd5fdb84283d6
ToppCellLPS_only|World / Treatment groups by lineage, cell group, cell type

HNRNPDL DDX3X

8.56e-04199102852cf595c2255983cff9045f2bb746d4391cf5ba
ToppCell3'-GW_trimst-1|3' / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KHDRBS1 HNRNPDL

8.56e-04199102ecfb6381e2971a3e355e661a6df0021914485e74
ToppCell10x3'2.3-week_12-13-Lymphocytic_B-B_lineage|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

HNRNPDL HNRNPR

8.56e-04199102fe3b7d540a644dfc6beea171c809b4d1ba4e188f
ToppCellMegakaryocytic-erythropoietic-Erythro-cells-Basophilic_Erythroblast|Megakaryocytic-erythropoietic / Lineage, cell class and subclass

KHDRBS1 HNRNPR

8.56e-041991026f159c1215439ec22374903124085746fa8da333
ToppCellEnterocyte_Progenitors|World / shred on cell type and cluster

KHDRBS1 HNRNPDL

8.56e-04199102776bcc887927dea9ebd76ec4338ce2225c319c2c
ToppCell10x5'v1-week_14-16-Lymphocytic_B-B_lineage-pre_pro_B_progenitor|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

HNRNPDL HNRNPR

8.56e-041991028daf945fc93169b0a4fa3ef9f4a87eedd52e314a
ToppCell(10)_Ciliated-(2)_GFP_FOXI1|(10)_Ciliated / shred by cell type by condition

KHDRBS1 DDX3Y

8.56e-0419910261b1ed2db71b96157b92b7535d1955a4033098da
ToppCell10x3'2.3-week_14-16-Lymphocytic_B-B_lineage|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

HNRNPDL HNRNPR

8.64e-042001020fd9a8730b7dc461ddf4586899d363541e72d8ba
ToppCellVE|World / Condition, Cell_class and T cell subcluster

KHDRBS1 HNRNPDL

8.64e-042001028ae7cb81de3ffac5acdf3466d4b516d80cac95d3
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SS18 DDX3Y

8.64e-04200102f0c338877e39226a90c4effe12f6501d33542a73
ToppCell10x5'v1-week_17-19-Lymphocytic_B|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

HNRNPDL HNRNPR

8.64e-04200102364f09eb9ae4913f5c80a29e943e1c0b2ffd5f93
ToppCellMS-IIF|MS / Disease, condition lineage and cell class

HNRNPDL DDX3Y

8.64e-04200102221f59edcfc18baece13184c2552d26022228146
ToppCellwk_08-11|World / Celltypes from embryonic and fetal-stage human lung

KHDRBS1 HNRNPDL

8.64e-04200102aa35c33762880a5e030a7e691c425524f7dbff8a
ToppCell10x3'2.3-week_14-16-Lymphocytic_B|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

HNRNPDL HNRNPR

8.64e-0420010219a4213f180ac2d29625d140b602a93a74ab3fdd
ToppCell10x_5'_v1-Non-neoplastic-Lymphoid-CD4/CD8-CD8_cytotoxic-Z|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

KHDRBS1 HNRNPDL

8.64e-0420010248d79c7a9a2d3c10b41e152baf28fb00a4729e48
ToppCell10x5'v1-week_17-19-Lymphocytic_B-B_lineage|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

HNRNPDL HNRNPR

8.64e-04200102c28d4ca51d2e2a3a22784ee251975f16a55b0297
ToppCellfacs-Brain_Non-Myeloid-Hippocampus|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SS18 DDX3Y

8.64e-04200102fc28f71ca1cd0fdae66009ae5afe175d22f2bd8c
ComputationalRNA splicing.

KHDRBS1 HNRNPDL HNRNPR

1.16e-056583MODULE_183
ComputationalNeighborhood of HDAC1

KHDRBS1 HNRNPDL HNRNPR

5.63e-0511083GNF2_HDAC1
ComputationalNeighborhood of CBFB

KHDRBS1 HNRNPDL

2.09e-043082GNF2_CBFB
ComputationalGenes in the cancer module 32.

KHDRBS1 HNRNPR DDX3Y

5.74e-0424183MODULE_32
ComputationalNeighborhood of DENR

KHDRBS1 HNRNPR

6.07e-045182GNF2_DENR
ComputationalNeighborhood of SMC1L1

KHDRBS1 HNRNPR

8.96e-046282MORF_SMC1L1
ComputationalNeighborhood of DDX5

HNRNPDL DDX3X

9.25e-046382GNF2_DDX5
ComputationalNeighborhood of TERF1

KHDRBS1 HNRNPR

1.05e-036782MORF_TERF1
ComputationalNeighborhood of KPNB1

KHDRBS1 HNRNPR

1.24e-037382GNF2_KPNB1
ComputationalGenes in the cancer module 83.

KHDRBS1 HNRNPR DDX3Y

1.31e-0332083MODULE_83
ComputationalNeighborhood of APEX1

KHDRBS1 HNRNPR

1.96e-039282GNF2_APEX1
ComputationalNeighborhood of UBE2N

KHDRBS1 HNRNPR

2.09e-039582MORF_UBE2N
ComputationalTranscription.

KHDRBS1 HNRNPDL

2.13e-039682MODULE_124
ComputationalNeighborhood of RRM1

KHDRBS1 HNRNPR

2.41e-0310282MORF_RRM1
ComputationalNeighborhood of DNMT1

KHDRBS1 HNRNPR

3.20e-0311882MORF_DNMT1
ComputationalNeighborhood of DAP3

KHDRBS1 HNRNPR

3.26e-0311982GNF2_DAP3
ComputationalNeighborhood of FBL

KHDRBS1 HNRNPR

4.86e-0314682GNF2_FBL
ComputationalNeighborhood of CDC10

KHDRBS1 HNRNPR

4.86e-0314682MORF_CDC10
ComputationalNeighborhood of RFC4

KHDRBS1 HNRNPR

5.19e-0315182MORF_RFC4
ComputationalNeighborhood of PPP1CC

KHDRBS1 HNRNPR

6.24e-0316682MORF_PPP1CC
ComputationalNeighborhood of HAT1

KHDRBS1 HNRNPR

6.92e-0317582MORF_HAT1
Drugbromovanin

HNRNPDL DDX3X HNRNPR DDX3Y

1.89e-07127104ctd:C515564
DrugAmoxicillin [26787-78-0]; Down 200; 11uM; MCF7; HT_HG-U133A

HNRNPDL DDX3X SS18

6.07e-051851032620_DN
DrugN6-methyladenosine [1867-73-8]; Down 200; 14.2uM; HL60; HT_HG-U133A

HNRNPDL DDX3X SS18

6.78e-051921031271_DN
DrugPaclitaxel [33069-62-4]; Down 200; 4.6uM; HL60; HG-U133A

HNRNPDL DDX3X HNRNPR

7.21e-051961032043_DN
DrugPNU-0293363 [326823-19-2]; Down 200; 10uM; PC3; HT_HG-U133A

HNRNPDL DDX3X SS18

7.21e-051961036563_DN
DrugAcetopromazine maleate salt [3598-37-6]; Down 200; 9uM; HL60; HG-U133A

HNRNPDL DDX3X HNRNPR

7.32e-051971031777_DN
DrugTrifluoperazine dihydrochloride [440-17-5]; Up 200; 8.4uM; PC3; HT_HG-U133A

KHDRBS1 DDX3X SS18

7.32e-051971036341_UP
DrugNiflumic acid [4394-00-7]; Up 200; 14.2uM; HL60; HT_HG-U133A

IBSP DDX3X SS18

7.54e-051991032399_UP
DrugAdana

DDX3X DDX3Y

1.09e-0436102CID000117765
DrugAC1NRA8H

DDX3X DDX3Y

7.59e-0495102CID005287756
DrugNitroprusside

HNRNPDL IBSP

1.03e-03111102ctd:D009599
Drugcarbonyl sulfide

DDX3X DDX3Y

1.13e-03116102CID000010039
Drugheparin pentasaccharide

DDX3X DDX3Y

1.73e-03144102CID000444410
DrugDB04649

FRMD7 SS18

1.83e-03148102CID005287847
DrugBuspirone

KHDRBS1 FAM98A HNRNPR

2.11e-03622103ctd:D002065
DrugPolychlorinated Biphenyls

HNRNPDL FAM98A DDX3Y

2.22e-03633103ctd:D011078
DrugProscillaridin A [466-06-8]; Up 200; 7.6uM; HL60; HT_HG-U133A

KHDRBS1 DDX3X

2.23e-031641022920_UP
DrugEmetine dihydrochloride [316-42-7]; Down 200; 7.2uM; HL60; HT_HG-U133A

DDX3X HNRNPR

2.26e-031651022145_DN
DrugHelveticoside [630-64-8]; Up 200; 7.4uM; PC3; HT_HG-U133A

DDX3X SS18

2.29e-031661024327_UP
DrugAC1NRA5C

KHDRBS1 HNRNPR

2.51e-03174102CID005287709
DrugCiclopirox ethanolamine [41621-49-2]; Up 200; 15uM; HL60; HT_HG-U133A

DDX3X SS18

2.51e-031741022456_UP
Drugtrichostatin A, Streptomyces sp.; Up 200; 1uM; PC3; HT_HG-U133A

KHDRBS1 SS18

2.57e-031761026886_UP
DrugPyrogallol

HNRNPDL DDX3X

2.62e-03178102ctd:D011748
Drugfisetin; Down 200; 50uM; PC3; HG-U133A

HNRNPDL DDX3X

2.62e-03178102579_DN
DrugCrotamiton [483-63-6]; Down 200; 19.6uM; MCF7; HT_HG-U133A

DDX3X SS18

2.65e-031791023388_DN
DrugTriamterene [396-01-0]; Up 200; 15.8uM; PC3; HT_HG-U133A

DDX3X SS18

2.65e-031791021819_UP
DrugQuercetine dihydrate [6151-25-3]; Down 200; 11.8uM; MCF7; HT_HG-U133A

HNRNPDL DDX3X

2.68e-031801022859_DN
DrugParthenolide [20554-84-1]; Down 200; 16.2uM; MCF7; HT_HG-U133A

HNRNPDL DDX3X

2.77e-031831025530_DN
DrugHarmine hydrochloride [343-27-1]; Down 200; 16uM; MCF7; HT_HG-U133A

HNRNPDL SS18

2.77e-031831022750_DN
DrugZuclopenthixol hydrochloride [633-59-0]; Up 200; 9.2uM; MCF7; HT_HG-U133A

DDX3X SS18

2.77e-031831024843_UP
DrugDilazep dihydrochloride [20153-98-4]; Down 200; 6uM; MCF7; HT_HG-U133A

HNRNPDL DDX3X

2.83e-031851024688_DN
DrugProchlorperazine dimaleate [84-02-6]; Down 200; 6.6uM; MCF7; HT_HG-U133A

DDX3X SS18

2.86e-031861025010_DN
DrugCefadroxil [50370-12-2]; Down 200; 11uM; HL60; HT_HG-U133A

DDX3X SS18

2.86e-031861021323_DN
DrugQuinacrine dihydrochloride dihydrate [6151-30-0]; Down 200; 7.8uM; HL60; HG-U133A

FAM98A HNRNPR

2.86e-031861021563_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A

DDX3X HNRNPR

2.89e-031871024302_DN
DrugSulfaphenazole [526-08-9]; Up 200; 12.8uM; PC3; HT_HG-U133A

HNRNPDL SS18

2.89e-031871021794_UP
DrugC768-0445; Down 200; 10uM; MCF7; HT_HG-U133A_EA

DDX3X SS18

2.89e-03187102973_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; HL60; HG-U133A

DDX3X HNRNPR

2.92e-031881021421_DN
DrugPicrotoxinin [17617-45-7]; Down 200; 13.6uM; HL60; HT_HG-U133A

DDX3X SS18

2.92e-031881022161_DN
DrugIsoflupredone acetate [338-98-7]; Up 200; 9.6uM; PC3; HT_HG-U133A

HNRNPDL SS18

2.92e-031881021832_UP
DrugNifuroxazide [965-52-6]; Down 200; 14.6uM; MCF7; HT_HG-U133A

DDX3X SS18

2.92e-031881024835_DN
DrugRescinnamin [24815-24-5]; Up 200; 6.4uM; MCF7; HT_HG-U133A

KHDRBS1 IBSP

2.92e-031881024386_UP
DrugNocodazole [31430-18-9]; Down 200; 13.2uM; MCF7; HT_HG-U133A

DDX3X SS18

2.95e-031891026793_DN
Drug17-AAG; Up 200; 1uM; PC3; HT_HG-U133A

DDX3X DDX3Y

2.95e-031891024430_UP
DrugHesperetin [520-33-2]; Down 200; 13.2uM; PC3; HT_HG-U133A

DDX3X SS18

2.95e-031891026750_DN
DrugGinkgolide A [15291-75-5]; Down 200; 9.8uM; MCF7; HT_HG-U133A

DDX3X SS18

2.95e-031891024121_DN
DrugCloperastine hydrochloride [14984-68-0]; Down 200; 11uM; PC3; HT_HG-U133A

DDX3X SS18

2.95e-031891024271_DN
DrugBenzbromarone [3562-84-3]; Up 200; 9.4uM; HL60; HT_HG-U133A

DDX3X SS18

2.95e-031891021291_UP
Drug0173570-0000 [211245-44-2]; Down 200; 10uM; PC3; HT_HG-U133A

HNRNPDL SS18

2.95e-031891023690_DN
DrugAlprostadil [745-65-3]; Up 200; 11.2uM; PC3; HT_HG-U133A

DDX3X SS18

2.95e-031891024099_UP
DrugDisopyramide [3737-09-5]; Down 200; 11.8uM; MCF7; HT_HG-U133A

DDX3X SS18

2.98e-031901027439_DN
DrugDeptropine citrate [2169-75-7]; Down 200; 7.6uM; HL60; HT_HG-U133A

DDX3X SS18

2.98e-031901023144_DN
DrugSelegiline hydrochloride [14611-52-0]; Down 200; 17.8uM; HL60; HT_HG-U133A

DDX3X SS18

2.98e-031901022465_DN
DrugLuteolin [491-70-3]; Down 200; 14uM; MCF7; HT_HG-U133A

HNRNPDL DDX3X

2.98e-031901023379_DN
Drugretinoic acid; Down 200; 1uM; MCF7; HT_HG-U133A

DDX3X SS18

2.98e-031901021636_DN
Drugresveratrol; Down 200; 50uM; MCF7; HG-U133A

HNRNPDL DDX3X

2.98e-03190102622_DN
DrugEstradiol-17 beta [50-28-2]; Down 200; 14.6uM; PC3; HT_HG-U133A

DDX3X SS18

2.98e-031901026718_DN
DrugMuramic acid, N-acetyl [10597-89-4]; Down 200; 13.6uM; PC3; HT_HG-U133A

DDX3X SS18

2.98e-031901024582_DN
DrugEthopropazine hydrochloride [1094-08-2]; Up 200; 11.4uM; PC3; HT_HG-U133A

KHDRBS1 IBSP

2.98e-031901026697_UP
DrugNilutamide [63612-50-0]; Down 200; 12.6uM; MCF7; HT_HG-U133A

DDX3X SS18

2.98e-031901025362_DN
DrugRoxithromycin [80214-83-1]; Down 200; 4.8uM; MCF7; HT_HG-U133A

DDX3X SS18

2.98e-031901023331_DN
DrugAzacytidine-5 [320-67-2]; Down 200; 16.4uM; PC3; HT_HG-U133A

DDX3X SS18

2.98e-031901024010_DN
Drugirinotecan

KHDRBS1 HNRNPDL DDX3X

2.99e-03703103ctd:C051890
DrugDiphenylpyraline hydrochloride [132-18-3]; Down 200; 12.6uM; PC3; HT_HG-U133A

DDX3X SS18

3.01e-031911024299_DN
DrugNitrofural [59-87-0]; Down 200; 20.2uM; PC3; HT_HG-U133A

DDX3X SS18

3.01e-031911026721_DN
Drugmonastrol; Up 200; 20uM; MCF7; HG-U133A

KHDRBS1 HNRNPR

3.01e-03191102614_UP
DrugPargyline hydrochloride [306-07-0]; Down 200; 20.4uM; HL60; HG-U133A

DDX3X HNRNPR

3.01e-031911021418_DN
DrugFludrocortisone acetate [514-36-3]; Up 200; 9.4uM; HL60; HT_HG-U133A

KHDRBS1 SS18

3.01e-031911022368_UP
DrugTriflupromazine hydrochloride [1098-60-8]; Up 200; 10.2uM; PC3; HT_HG-U133A

DDX3X SS18

3.01e-031911021813_UP
DrugPNU-0230031 [267429-39-0]; Down 200; 10uM; PC3; HT_HG-U133A

HNRNPDL DDX3X

3.04e-031921024288_DN
Drug0317956-0000 [391210-11-0]; Down 200; 1uM; PC3; HT_HG-U133A

DDX3X SS18

3.04e-031921024334_DN
DrugClomiphene citrate (Z,E) [50-41-9]; Down 200; 6.6uM; MCF7; HT_HG-U133A

DDX3X SS18

3.04e-031921022624_DN
DrugFusaric acid [536-69-6]; Down 200; 22.4uM; MCF7; HT_HG-U133A

DDX3X SS18

3.04e-031921023245_DN
DrugNorethindrone [68-22-4]; Up 200; 13.4uM; HL60; HT_HG-U133A

KHDRBS1 SS18

3.04e-031921022383_UP
DrugMonobenzone [103-16-2]; Down 200; 20uM; PC3; HT_HG-U133A

DDX3X SS18

3.04e-031921026713_DN
DrugBenfluorex hydrochloride [23642-66-2]; Down 200; 10.4uM; HL60; HT_HG-U133A

DDX3X SS18

3.04e-031921021266_DN
DrugTranylcypromine hydrochloride [1986-47-6]; Down 200; 23.6uM; PC3; HT_HG-U133A

DDX3X SS18

3.04e-031921022101_DN
DrugLY 294002; Down 200; 10uM; MCF7; HT_HG-U133A

HNRNPDL DDX3X

3.04e-031921021661_DN
Drug2-propylpentanoic acid; Down 200; 50uM; MCF7; HT_HG-U133A

DDX3X SS18

3.04e-031921021647_DN
DrugSalsolinol hydrobromide [38221-21-5]; Down 200; 15.4uM; MCF7; HT_HG-U133A

DDX3X SS18

3.04e-031921024816_DN
DrugTolbutamide [64-77-7]; Down 200; 14.8uM; PC3; HT_HG-U133A

KHDRBS1 SS18

3.04e-031921023804_DN
Drugaspirin, USP; Down 200; 100uM; HL60; HT_HG-U133A

DDX3X SS18

3.04e-031921026164_DN
DrugPipemidic acid [51940-44-4]; Down 200; 13.2uM; PC3; HT_HG-U133A

DDX3X SS18

3.04e-031921026752_DN
DrugGramine [87-52-5]; Up 200; 23uM; MCF7; HT_HG-U133A

KHDRBS1 DDX3X

3.08e-031931024118_UP
DrugSpironolactone [52-01-7]; Down 200; 9.6uM; HL60; HG-U133A

HNRNPDL HNRNPR

3.08e-031931021380_DN
DrugMethylergometrine maleate [113-42-8]; Down 200; 8.8uM; PC3; HT_HG-U133A

DDX3X SS18

3.08e-031931026704_DN
Diseasechildhood medulloblastoma (implicated_via_orthology)

DDX3X DDX3Y

8.27e-08292DOID:3869 (implicated_via_orthology)
DiseaseSertoli cell-only syndrome (implicated_via_orthology)

DDX3X DDX3Y

4.96e-07492DOID:0050457 (implicated_via_orthology)
DiseaseMalignant neoplasm of breast

IBSP DDX3X HNRNPR

3.43e-03107493C0006142
DiseaseIntellectual Disability

DDX3X HNRNPR

7.68e-0344792C3714756
DiseaseMammary Neoplasms, Human

IBSP HNRNPR

1.05e-0252592C1257931
DiseaseMammary Carcinoma, Human

IBSP HNRNPR

1.05e-0252592C4704874
DiseaseMammary Neoplasms

IBSP HNRNPR

1.05e-0252792C1458155
DiseaseBreast Carcinoma

IBSP HNRNPR

1.10e-0253892C0678222

Protein segments in the cluster

PeptideGeneStartEntry
NYGYGQGYADYSGQQ

HNRNPDL

386

O14979
GFYNSDGYGGNYNSQ

DDX3X

641

O00571
LAYGGGYYQNVNGVH

FRMD7

356

Q6ZUT3
QGGDYSGNYGYNNDN

HNRNPR

606

O43390
QGDSEYYDYGHGEVQ

KHDRBS1

391

Q07666
YNSDGYGGNYNSQGV

DDX3Y

641

O15523
GYQGGGYQQDNRYQD

FAM98A

436

Q8NCA5
KGQGYDGYDGQNYYH

IBSP

301

P21815
YGQSHHYGGEGRYEE

RBMXL3

411

Q8N7X1
GQEDYYGDQYSHGGQ

SS18

266

Q15532
DSSQHYYEGGNSQYG

SS18

316

Q15532